Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1I16 chain A sc2

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
33
A
VAL
0.79
0.56
0.36
10
37
A
LYS
0.87
0.25
0.66
10
38
A
MET
0.79
0.66
0.76
10
39
A
SER
0.60
0.36
0.74
10
40
A
ALA
0.72
0.38
0.74
10
41
A
GLY
0.94
0.41
0.58
10
42
A
LEU
0.93
0.70
0.46
10
43
A
GLY
1.00
0.41
0.60
10
47
A
GLU
0.75
0.33
0.55
3
48
A
GLY
0.94
0.41
0.56
1
49
A
GLY
0.90
0.41
0.62
1
51
A
GLY
0.75
0.41
0.71
1
52
A
SER
0.79
0.36
0.77
1
53
A
LEU
0.53
0.70
0.73
1
54
A
HIS
0.49
0.60
0.79
1
55
A
GLY
0.80
0.41
0.70
1
62
A
ASN
0.81
0.39
0.56
8
63
A
ARG
0.79
0.51
0.71
10
64
A
ILE
0.78
0.64
0.54
10
65
A
PHE
0.73
1.00
0.69
10
66
A
LYS
0.75
0.25
0.78
10
67
A
GLY
0.82
0.41
0.75
10
68
A
ALA
0.92
0.38
0.67
10
69
A
ALA
0.82
0.38
0.60
2
70
A
SER
0.92
0.36
0.75
10
71
A
GLU
0.69
0.33
0.73
10
72
A
GLN
0.64
0.43
0.64
10
73
A
SER
0.80
0.36
0.68
10
74
A
GLU
0.91
0.33
0.61
10
78
A
PRO
0.64
0.47
0.54
8
93
A
LEU
0.74
0.70
0.53
1
95
A
ARG
0.84
0.51
0.62
3
96
A
PHE
0.73
1.00
0.71
1
97
A
GLU
0.76
0.33
0.67
1
99
A
TRP
0.87
0.99
0.49
10
100
A
ASN
0.70
0.39
0.65
6
101
A
ILE
0.64
0.64
0.57
6
103
A
LYS
0.86
0.25
0.67
6
104
A
ALA
0.52
0.38
0.70
10
105
A
LEU
0.72
0.70
0.58
10
106
A
PRO
0.72
0.47
0.69
10
107
A
ASP
0.67
0.32
0.76
10
108
A
GLY
0.85
0.41
0.68
10
109
A
PRO
0.71
0.47
0.63
10
31
A
CYS
0.52
0.64
0.35
1
32
A
THR
0.62
0.33
0.38
2
33
A
VAL
0.79
0.56
0.37
10
34
A
THR
0.67
0.33
0.50
1
36
A
GLU
0.67
0.33
0.66
3
37
A
LYS
0.87
0.25
0.67
10
38
A
MET
0.79
0.66
0.79
10
39
A
SER
0.60
0.36
0.77
10
40
A
ALA
0.72
0.38
0.72
10
45
A
SER
0.89
0.36
0.51
5
47
A
GLU
0.75
0.33
0.53
7
48
A
GLY
0.94
0.41
0.53
1
49
A
GLY
0.90
0.41
0.60
3
50
A
LYS
0.67
0.25
0.70
4
51
A
GLY
0.75
0.41
0.67
3
62
A
ASN
0.81
0.39
0.54
9
63
A
ARG
0.79
0.51
0.69
10
64
A
ILE
0.78
0.64
0.52
10
65
A
PHE
0.73
1.00
0.68
10
66
A
LYS
0.75
0.25
0.69
10
67
A
GLY
0.82
0.41
0.73
10
68
A
ALA
0.92
0.38
0.69
10
69
A
ALA
0.82
0.38
0.64
10
70
A
SER
0.92
0.36
0.67
10
71
A
GLU
0.69
0.33
0.60
10
72
A
GLN
0.64
0.43
0.67
10
73
A
SER
0.80
0.36
0.70
10
74
A
GLU
0.91
0.33
0.59
10
76
A
VAL
0.82
0.56
0.42
8
78
A
PRO
0.64
0.47
0.49
9
79
A
GLY
0.94
0.41
0.39
1
84
A
GLN
0.73
0.43
0.29
8
86
A
GLY
0.88
0.41
0.42
7
87
A
GLY
0.85
0.41
0.52
10
89
A
ALA
0.51
0.38
0.44
9
93
A
LEU
0.74
0.70
0.59
3
94
A
THR
0.72
0.33
0.65
3
95
A
ARG
0.84
0.51
0.61
7
96
A
PHE
0.73
1.00
0.71
3
97
A
GLU
0.76
0.33
0.67
3
99
A
TRP
0.87
0.99
0.51
10
100
A
ASN
0.70
0.39
0.68
10
101
A
ILE
0.64
0.64
0.61
10
103
A
LYS
0.86
0.25
0.67
10
104
A
ALA
0.52
0.38
0.72
10
105
A
LEU
0.72
0.70
0.61
10
106
A
PRO
0.72
0.47
0.70
10
107
A
ASP
0.67
0.32
0.77
10
108
A
GLY
0.85
0.41
0.69
10
109
A
PRO
0.71
0.47
0.63
10
113
A
VAL
0.71
0.56
0.19
1
33
A
VAL
0.79
0.56
0.44
10
35
A
LEU
0.85
0.70
0.43
9
36
A
GLU
0.67
0.33
0.69
4
37
A
LYS
0.87
0.25
0.63
10
38
A
MET
0.79
0.66
0.74
10
39
A
SER
0.60
0.36
0.73
10
40
A
ALA
0.72
0.38
0.71
10
41
A
GLY
0.94
0.41
0.57
10
42
A
LEU
0.93
0.70
0.45
10
43
A
GLY
1.00
0.41
0.50
10
45
A
SER
0.89
0.36
0.37
10
47
A
GLU
0.75
0.33
0.35
7
48
A
GLY
0.94
0.41
0.41
7
49
A
GLY
0.90
0.41
0.51
5
51
A
GLY
0.75
0.41
0.67
5
62
A
ASN
0.81
0.39
0.33
10
63
A
ARG
0.79
0.51
0.54
10
64
A
ILE
0.78
0.64
0.36
10
65
A
PHE
0.73
1.00
0.57
10
66
A
LYS
0.75
0.25
0.63
10
67
A
GLY
0.82
0.41
0.53
10
68
A
ALA
0.92
0.38
0.60
10
69
A
ALA
0.82
0.38
0.59
9
70
A
SER
0.92
0.36
0.72
10
71
A
GLU
0.69
0.33
0.79
10
72
A
GLN
0.64
0.43
0.70
10
73
A
SER
0.80
0.36
0.65
10
74
A
GLU
0.91
0.33
0.53
10
84
A
GLN
0.73
0.43
0.47
4
86
A
GLY
0.88
0.41
0.54
4
87
A
GLY
0.85
0.41
0.62
9
89
A
ALA
0.51
0.38
0.56
3
93
A
LEU
0.74
0.70
0.62
3
94
A
THR
0.72
0.33
0.63
5
95
A
ARG
0.84
0.51
0.52
7
96
A
PHE
0.73
1.00
0.65
6
97
A
GLU
0.76
0.33
0.67
6
99
A
TRP
0.87
0.99
0.46
10
100
A
ASN
0.70
0.39
0.67
10
101
A
ILE
0.64
0.64
0.68
10
103
A
LYS
0.86
0.25
0.67
6
104
A
ALA
0.52
0.38
0.77
10
105
A
LEU
0.72
0.70
0.74
10
106
A
PRO
0.72
0.47
0.81
10
107
A
ASP
0.67
0.32
0.80
10
108
A
GLY
0.85
0.41
0.76
10
109
A
PRO
0.71
0.47
0.74
10
113
A
VAL
0.71
0.56
0.39
4
31
A
CYS
0.52
0.64
0.32
2
32
A
THR
0.62
0.33
0.47
4
33
A
VAL
0.79
0.56
0.36
6
34
A
THR
0.67
0.33
0.53
2
36
A
GLU
0.67
0.33
0.65
9
37
A
LYS
0.87
0.25
0.64
10
38
A
MET
0.79
0.66
0.77
10
39
A
SER
0.60
0.36
0.74
10
40
A
ALA
0.72
0.38
0.67
10
41
A
GLY
0.94
0.41
0.58
10
49
A
GLY
0.90
0.41
0.59
1
51
A
GLY
0.75
0.41
0.73
1
63
A
ARG
0.79
0.51
0.54
10
64
A
ILE
0.78
0.64
0.36
10
65
A
PHE
0.73
1.00
0.57
10
66
A
LYS
0.75
0.25
0.57
10
67
A
GLY
0.82
0.41
0.65
10
68
A
ALA
0.92
0.38
0.63
10
69
A
ALA
0.82
0.38
0.58
10
70
A
SER
0.92
0.36
0.61
10
71
A
GLU
0.69
0.33
0.71
10
72
A
GLN
0.64
0.43
0.58
10
73
A
SER
0.80
0.36
0.59
10
74
A
GLU
0.91
0.33
0.47
10
76
A
VAL
0.82
0.56
0.28
8
84
A
GLN
0.73
0.43
0.49
4
86
A
GLY
0.88
0.41
0.53
6
87
A
GLY
0.85
0.41
0.63
7
89
A
ALA
0.51
0.38
0.59
7
93
A
LEU
0.74
0.70
0.68
3
94
A
THR
0.72
0.33
0.71
6
95
A
ARG
0.84
0.51
0.57
2
96
A
PHE
0.73
1.00
0.71
7
97
A
GLU
0.76
0.33
0.74
7
99
A
TRP
0.87
0.99
0.49
10
100
A
ASN
0.70
0.39
0.71
10
101
A
ILE
0.64
0.64
0.70
10
103
A
LYS
0.86
0.25
0.67
10
104
A
ALA
0.52
0.38
0.78
10
105
A
LEU
0.72
0.70
0.73
10
106
A
PRO
0.72
0.47
0.80
10
107
A
ASP
0.67
0.32
0.79
10
108
A
GLY
0.85
0.41
0.73
10
109
A
PRO
0.71
0.47
0.70
10
111
A
THR
0.69
0.33
0.53
2
113
A
VAL
0.71
0.56
0.38
4
32
A
THR
0.62
0.33
0.47
10
33
A
VAL
0.79
0.56
0.44
5
37
A
LYS
0.87
0.25
0.65
9
38
A
MET
0.79
0.66
0.80
10
39
A
SER
0.60
0.36
0.77
10
40
A
ALA
0.72
0.38
0.79
10
41
A
GLY
0.94
0.41
0.66
10
45
A
SER
0.89
0.36
0.49
1
47
A
GLU
0.75
0.33
0.45
2
48
A
GLY
0.94
0.41
0.43
2
49
A
GLY
0.90
0.41
0.51
1
62
A
ASN
0.81
0.39
0.50
10
63
A
ARG
0.79
0.51
0.68
10
64
A
ILE
0.78
0.64
0.53
10
65
A
PHE
0.73
1.00
0.69
10
66
A
LYS
0.75
0.25
0.72
10
67
A
GLY
0.82
0.41
0.74
10
69
A
ALA
0.82
0.38
0.70
10
70
A
SER
0.92
0.36
0.75
10
71
A
GLU
0.69
0.33
0.79
10
72
A
GLN
0.64
0.43
0.68
10
73
A
SER
0.80
0.36
0.67
10
74
A
GLU
0.91
0.33
0.61
10
78
A
PRO
0.64
0.47
0.48
10
79
A
GLY
0.94
0.41
0.34
9
86
A
GLY
0.88
0.41
0.54
6
87
A
GLY
0.85
0.41
0.57
10
89
A
ALA
0.51
0.38
0.43
1
93
A
LEU
0.74
0.70
0.55
1
94
A
THR
0.72
0.33
0.62
1
95
A
ARG
0.84
0.51
0.55
4
96
A
PHE
0.73
1.00
0.67
2
97
A
GLU
0.76
0.33
0.67
2
99
A
TRP
0.87
0.99
0.51
10
100
A
ASN
0.70
0.39
0.67
10
101
A
ILE
0.64
0.64
0.64
10
103
A
LYS
0.86
0.25
0.72
10
104
A
ALA
0.52
0.38
0.76
10
105
A
LEU
0.72
0.70
0.69
10
106
A
PRO
0.72
0.47
0.78
10
107
A
ASP
0.67
0.32
0.81
10
108
A
GLY
0.85
0.41
0.75
10
109
A
PRO
0.71
0.47
0.72
10
32
A
THR
0.62
0.33
0.39
10
33
A
VAL
0.79
0.56
0.36
10
36
A
GLU
0.67
0.33
0.62
1
37
A
LYS
0.87
0.25
0.60
10
38
A
MET
0.79
0.66
0.75
10
39
A
SER
0.60
0.36
0.76
10
40
A
ALA
0.72
0.38
0.69
10
43
A
GLY
1.00
0.41
0.54
10
45
A
SER
0.89
0.36
0.47
7
47
A
GLU
0.75
0.33
0.54
3
52
A
SER
0.79
0.36
0.63
3
62
A
ASN
0.81
0.39
0.54
10
63
A
ARG
0.79
0.51
0.67
10
64
A
ILE
0.78
0.64
0.50
10
65
A
PHE
0.73
1.00
0.64
10
66
A
LYS
0.75
0.25
0.71
10
67
A
GLY
0.82
0.41
0.71
10
68
A
ALA
0.92
0.38
0.71
10
69
A
ALA
0.82
0.38
0.62
10
70
A
SER
0.92
0.36
0.65
10
71
A
GLU
0.69
0.33
0.74
10
72
A
GLN
0.64
0.43
0.62
10
73
A
SER
0.80
0.36
0.66
10
74
A
GLU
0.91
0.33
0.60
10
76
A
VAL
0.82
0.56
0.42
10
84
A
GLN
0.73
0.43
0.24
2
87
A
GLY
0.85
0.41
0.43
5
89
A
ALA
0.51
0.38
0.37
2
95
A
ARG
0.84
0.51
0.59
3
99
A
TRP
0.87
0.99
0.47
10
100
A
ASN
0.70
0.39
0.63
7
101
A
ILE
0.64
0.64
0.55
7
103
A
LYS
0.86
0.25
0.63
10
104
A
ALA
0.52
0.38
0.66
10
105
A
LEU
0.72
0.70
0.56
10
106
A
PRO
0.72
0.47
0.65
10
107
A
ASP
0.67
0.32
0.71
10
108
A
GLY
0.85
0.41
0.63
10
109
A
PRO
0.71
0.47
0.59
10
33
A
VAL
0.79
0.56
0.23
10
37
A
LYS
0.87
0.25
0.64
10
38
A
MET
0.79
0.66
0.76
10
39
A
SER
0.60
0.36
0.77
10
40
A
ALA
0.72
0.38
0.69
10
41
A
GLY
0.94
0.41
0.58
10
43
A
GLY
1.00
0.41
0.51
10
45
A
SER
0.89
0.36
0.47
2
62
A
ASN
0.81
0.39
0.52
10
63
A
ARG
0.79
0.51
0.64
10
64
A
ILE
0.78
0.64
0.42
10
65
A
PHE
0.73
1.00
0.61
10
66
A
LYS
0.75
0.25
0.69
10
67
A
GLY
0.82
0.41
0.64
10
68
A
ALA
0.92
0.38
0.61
10
69
A
ALA
0.82
0.38
0.55
5
70
A
SER
0.92
0.36
0.55
10
71
A
GLU
0.69
0.33
0.64
10
73
A
SER
0.80
0.36
0.49
2
76
A
VAL
0.82
0.56
0.26
10
78
A
PRO
0.64
0.47
0.35
10
79
A
GLY
0.94
0.41
0.35
7
87
A
GLY
0.85
0.41
0.58
10
89
A
ALA
0.51
0.38
0.55
5
99
A
TRP
0.87
0.99
0.53
10
100
A
ASN
0.70
0.39
0.72
9
101
A
ILE
0.64
0.64
0.69
10
103
A
LYS
0.86
0.25
0.69
10
104
A
ALA
0.52
0.38
0.77
10
105
A
LEU
0.72
0.70
0.69
10
106
A
PRO
0.72
0.47
0.76
10
107
A
ASP
0.67
0.32
0.78
10
108
A
GLY
0.85
0.41
0.69
10
109
A
PRO
0.71
0.47
0.64
10
116
A
ARG
0.73
0.51
0.32
7
33
A
VAL
0.79
0.56
0.44
10
37
A
LYS
0.87
0.25
0.72
10
38
A
MET
0.79
0.66
0.81
10
39
A
SER
0.60
0.36
0.84
10
40
A
ALA
0.72
0.38
0.75
10
41
A
GLY
0.94
0.41
0.65
10
45
A
SER
0.89
0.36
0.50
8
47
A
GLU
0.75
0.33
0.45
5
48
A
GLY
0.94
0.41
0.46
1
49
A
GLY
0.90
0.41
0.53
3
51
A
GLY
0.75
0.41
0.61
3
62
A
ASN
0.81
0.39
0.46
10
63
A
ARG
0.79
0.51
0.66
10
64
A
ILE
0.78
0.64
0.51
10
65
A
PHE
0.73
1.00
0.68
10
66
A
LYS
0.75
0.25
0.74
10
67
A
GLY
0.82
0.41
0.66
10
68
A
ALA
0.92
0.38
0.73
10
69
A
ALA
0.82
0.38
0.70
10
70
A
SER
0.92
0.36
0.72
10
71
A
GLU
0.69
0.33
0.74
10
72
A
GLN
0.64
0.43
0.66
10
73
A
SER
0.80
0.36
0.70
10
74
A
GLU
0.91
0.33
0.60
10
76
A
VAL
0.82
0.56
0.43
10
78
A
PRO
0.64
0.47
0.43
10
79
A
GLY
0.94
0.41
0.29
5
87
A
GLY
0.85
0.41
0.61
10
89
A
ALA
0.51
0.38
0.51
10
93
A
LEU
0.74
0.70
0.59
1
94
A
THR
0.72
0.33
0.64
4
95
A
ARG
0.84
0.51
0.57
5
96
A
PHE
0.73
1.00
0.69
4
97
A
GLU
0.76
0.33
0.69
1
99
A
TRP
0.87
0.99
0.53
10
100
A
ASN
0.70
0.39
0.70
7
101
A
ILE
0.64
0.64
0.68
10
103
A
LYS
0.86
0.25
0.72
6
104
A
ALA
0.52
0.38
0.79
10
105
A
LEU
0.72
0.70
0.70
10
106
A
PRO
0.72
0.47
0.80
10
107
A
ASP
0.67
0.32
0.83
10
108
A
GLY
0.85
0.41
0.76
10
109
A
PRO
0.71
0.47
0.73
10
32
A
THR
0.62
0.33
0.29
10
33
A
VAL
0.79
0.56
0.31
10
36
A
GLU
0.67
0.33
0.63
1
37
A
LYS
0.87
0.25
0.65
10
38
A
MET
0.79
0.66
0.75
10
39
A
SER
0.60
0.36
0.80
10
40
A
ALA
0.72
0.38
0.75
10
41
A
GLY
0.94
0.41
0.63
10
43
A
GLY
1.00
0.41
0.60
10
45
A
SER
0.89
0.36
0.52
5
47
A
GLU
0.75
0.33
0.57
6
48
A
GLY
0.94
0.41
0.58
4
50
A
LYS
0.67
0.25
0.74
3
62
A
ASN
0.81
0.39
0.57
10
63
A
ARG
0.79
0.51
0.72
10
64
A
ILE
0.78
0.64
0.56
10
65
A
PHE
0.73
1.00
0.70
10
66
A
LYS
0.75
0.25
0.74
10
67
A
GLY
0.82
0.41
0.62
10
68
A
ALA
0.92
0.38
0.66
10
69
A
ALA
0.82
0.38
0.59
10
70
A
SER
0.92
0.36
0.70
10
71
A
GLU
0.69
0.33
0.74
10
72
A
GLN
0.64
0.43
0.60
10
73
A
SER
0.80
0.36
0.67
10
74
A
GLU
0.91
0.33
0.61
10
76
A
VAL
0.82
0.56
0.44
10
78
A
PRO
0.64
0.47
0.56
10
79
A
GLY
0.94
0.41
0.46
9
86
A
GLY
0.88
0.41
0.38
1
87
A
GLY
0.85
0.41
0.48
10
89
A
ALA
0.51
0.38
0.41
7
93
A
LEU
0.74
0.70
0.59
1
94
A
THR
0.72
0.33
0.65
1
95
A
ARG
0.84
0.51
0.55
6
96
A
PHE
0.73
1.00
0.72
1
97
A
GLU
0.76
0.33
0.69
1
99
A
TRP
0.87
0.99
0.52
10
100
A
ASN
0.70
0.39
0.68
10
101
A
ILE
0.64
0.64
0.62
10
103
A
LYS
0.86
0.25
0.69
10
104
A
ALA
0.52
0.38
0.73
10
105
A
LEU
0.72
0.70
0.63
10
106
A
PRO
0.72
0.47
0.71
10
107
A
ASP
0.67
0.32
0.76
10
108
A
GLY
0.85
0.41
0.67
10
109
A
PRO
0.71
0.47
0.61
10
116
A
ARG
0.73
0.51
0.45
9
31
A
CYS
0.52
0.64
0.37
10
36
A
GLU
0.67
0.33
0.73
5
37
A
LYS
0.87
0.25
0.72
10
38
A
MET
0.79
0.66
0.83
10
39
A
SER
0.60
0.36
0.85
10
40
A
ALA
0.72
0.38
0.78
10
43
A
GLY
1.00
0.41
0.63
10
45
A
SER
0.89
0.36
0.52
8
62
A
ASN
0.81
0.39
0.51
1
63
A
ARG
0.79
0.51
0.66
10
64
A
ILE
0.78
0.64
0.53
10
65
A
PHE
0.73
1.00
0.69
10
66
A
LYS
0.75
0.25
0.79
10
67
A
GLY
0.82
0.41
0.73
10
68
A
ALA
0.92
0.38
0.78
10
69
A
ALA
0.82
0.38
0.70
10
70
A
SER
0.92
0.36
0.71
10
71
A
GLU
0.69
0.33
0.73
10
72
A
GLN
0.64
0.43
0.62
10
73
A
SER
0.80
0.36
0.70
10
74
A
GLU
0.91
0.33
0.63
10
76
A
VAL
0.82
0.56
0.46
10
78
A
PRO
0.64
0.47
0.49
9
79
A
GLY
0.94
0.41
0.36
6
93
A
LEU
0.74
0.70
0.54
1
94
A
THR
0.72
0.33
0.59
1
95
A
ARG
0.84
0.51
0.59
2
96
A
PHE
0.73
1.00
0.69
10
97
A
GLU
0.76
0.33
0.66
2
99
A
TRP
0.87
0.99
0.53
10
100
A
ASN
0.70
0.39
0.68
10
101
A
ILE
0.64
0.64
0.63
10
103
A
LYS
0.86
0.25
0.72
10
104
A
ALA
0.52
0.38
0.76
10
105
A
LEU
0.72
0.70
0.68
10
106
A
PRO
0.72
0.47
0.75
10
107
A
ASP
0.67
0.32
0.81
10
108
A
GLY
0.85
0.41
0.75
10
109
A
PRO
0.71
0.47
0.71
10
32
A
THR
0.62
0.33
0.30
9
33
A
VAL
0.79
0.56
0.22
8
36
A
GLU
0.67
0.33
0.57
1
37
A
LYS
0.87
0.25
0.65
10
38
A
MET
0.79
0.66
0.72
10
39
A
SER
0.60
0.36
0.74
10
40
A
ALA
0.72
0.38
0.72
10
41
A
GLY
0.94
0.41
0.59
10
62
A
ASN
0.81
0.39
0.49
1
63
A
ARG
0.79
0.51
0.65
10
64
A
ILE
0.78
0.64
0.41
10
65
A
PHE
0.73
1.00
0.60
10
66
A
LYS
0.75
0.25
0.66
10
67
A
GLY
0.82
0.41
0.67
10
68
A
ALA
0.92
0.38
0.60
10
69
A
ALA
0.82
0.38
0.53
9
70
A
SER
0.92
0.36
0.53
10
71
A
GLU
0.69
0.33
0.62
10
72
A
GLN
0.64
0.43
0.46
10
73
A
SER
0.80
0.36
0.48
10
74
A
GLU
0.91
0.33
0.42
10
84
A
GLN
0.73
0.43
0.35
6
86
A
GLY
0.88
0.41
0.47
8
87
A
GLY
0.85
0.41
0.56
10
89
A
ALA
0.51
0.38
0.52
9
93
A
LEU
0.74
0.70
0.66
1
94
A
THR
0.72
0.33
0.71
2
95
A
ARG
0.84
0.51
0.62
3
96
A
PHE
0.73
1.00
0.72
4
97
A
GLU
0.76
0.33
0.73
4
99
A
TRP
0.87
0.99
0.51
10
100
A
ASN
0.70
0.39
0.70
10
101
A
ILE
0.64
0.64
0.67
10
103
A
LYS
0.86
0.25
0.68
10
104
A
ALA
0.52
0.38
0.75
10
105
A
LEU
0.72
0.70
0.63
10
106
A
PRO
0.72
0.47
0.73
10
107
A
ASP
0.67
0.32
0.75
10
108
A
GLY
0.85
0.41
0.66
10
109
A
PRO
0.71
0.47
0.61
10
32
A
THR
0.62
0.33
0.47
10
34
A
THR
0.67
0.33
0.56
1
36
A
GLU
0.67
0.33
0.67
5
37
A
LYS
0.87
0.25
0.67
10
38
A
MET
0.79
0.66
0.80
10
39
A
SER
0.60
0.36
0.76
10
40
A
ALA
0.72
0.38
0.75
10
43
A
GLY
1.00
0.41
0.55
10
63
A
ARG
0.79
0.51
0.55
10
64
A
ILE
0.78
0.64
0.39
10
65
A
PHE
0.73
1.00
0.59
10
66
A
LYS
0.75
0.25
0.62
10
67
A
GLY
0.82
0.41
0.69
10
68
A
ALA
0.92
0.38
0.65
10
69
A
ALA
0.82
0.38
0.61
10
70
A
SER
0.92
0.36
0.73
10
71
A
GLU
0.69
0.33
0.70
10
72
A
GLN
0.64
0.43
0.63
10
73
A
SER
0.80
0.36
0.65
10
74
A
GLU
0.91
0.33
0.53
10
76
A
VAL
0.82
0.56
0.33
8
84
A
GLN
0.73
0.43
0.44
9
86
A
GLY
0.88
0.41
0.50
8
87
A
GLY
0.85
0.41
0.62
10
89
A
ALA
0.51
0.38
0.54
10
93
A
LEU
0.74
0.70
0.65
1
94
A
THR
0.72
0.33
0.64
1
95
A
ARG
0.84
0.51
0.53
8
96
A
PHE
0.73
1.00
0.66
8
97
A
GLU
0.76
0.33
0.69
8
99
A
TRP
0.87
0.99
0.48
10
100
A
ASN
0.70
0.39
0.68
10
101
A
ILE
0.64
0.64
0.68
10
103
A
LYS
0.86
0.25
0.68
10
104
A
ALA
0.52
0.38
0.78
10
105
A
LEU
0.72
0.70
0.71
10
106
A
PRO
0.72
0.47
0.79
10
107
A
ASP
0.67
0.32
0.80
10
108
A
GLY
0.85
0.41
0.74
10
109
A
PRO
0.71
0.47
0.72
10
32
A
THR
0.62
0.33
0.48
10
33
A
VAL
0.79
0.56
0.47
10
37
A
LYS
0.87
0.25
0.65
10
38
A
MET
0.79
0.66
0.78
10
39
A
SER
0.60
0.36
0.79
10
40
A
ALA
0.72
0.38
0.71
10
41
A
GLY
0.94
0.41
0.57
10
43
A
GLY
1.00
0.41
0.59
10
45
A
SER
0.89
0.36
0.44
9
47
A
GLU
0.75
0.33
0.40
3
48
A
GLY
0.94
0.41
0.36
1
49
A
GLY
0.90
0.41
0.45
3
50
A
LYS
0.67
0.25
0.58
1
51
A
GLY
0.75
0.41
0.57
4
52
A
SER
0.79
0.36
0.62
1
62
A
ASN
0.81
0.39
0.49
10
63
A
ARG
0.79
0.51
0.64
10
64
A
ILE
0.78
0.64
0.54
10
65
A
PHE
0.73
1.00
0.67
10
66
A
LYS
0.75
0.25
0.77
10
67
A
GLY
0.82
0.41
0.67
10
68
A
ALA
0.92
0.38
0.68
10
69
A
ALA
0.82
0.38
0.72
10
70
A
SER
0.92
0.36
0.75
10
71
A
GLU
0.69
0.33
0.78
10
72
A
GLN
0.64
0.43
0.70
10
73
A
SER
0.80
0.36
0.76
10
74
A
GLU
0.91
0.33
0.70
10
76
A
VAL
0.82
0.56
0.49
7
78
A
PRO
0.64
0.47
0.55
10
79
A
GLY
0.94
0.41
0.40
10
86
A
GLY
0.88
0.41
0.40
2
87
A
GLY
0.85
0.41
0.43
7
93
A
LEU
0.74
0.70
0.38
8
94
A
THR
0.72
0.33
0.48
5
95
A
ARG
0.84
0.51
0.47
10
96
A
PHE
0.73
1.00
0.60
8
97
A
GLU
0.76
0.33
0.54
8
99
A
TRP
0.87
0.99
0.42
10
100
A
ASN
0.70
0.39
0.56
10
101
A
ILE
0.64
0.64
0.49
10
103
A
LYS
0.86
0.25
0.60
10
104
A
ALA
0.52
0.38
0.64
10
105
A
LEU
0.72
0.70
0.57
10
106
A
PRO
0.72
0.47
0.69
10
107
A
ASP
0.67
0.32
0.75
10
108
A
GLY
0.85
0.41
0.69
10
109
A
PRO
0.71
0.47
0.67
10
32
A
THR
0.62
0.33
0.57
10
36
A
GLU
0.67
0.33
0.72
3
37
A
LYS
0.87
0.25
0.70
10
38
A
MET
0.79
0.66
0.80
10
39
A
SER
0.60
0.36
0.81
10
40
A
ALA
0.72
0.38
0.71
10
43
A
GLY
1.00
0.41
0.51
10
45
A
SER
0.89
0.36
0.37
5
49
A
GLY
0.90
0.41
0.47
2
50
A
LYS
0.67
0.25
0.63
3
51
A
GLY
0.75
0.41
0.65
2
52
A
SER
0.79
0.36
0.64
2
62
A
ASN
0.81
0.39
0.33
2
63
A
ARG
0.79
0.51
0.51
10
64
A
ILE
0.78
0.64
0.35
10
65
A
PHE
0.73
1.00
0.57
10
66
A
LYS
0.75
0.25
0.67
10
67
A
GLY
0.82
0.41
0.67
10
68
A
ALA
0.92
0.38
0.67
10
70
A
SER
0.92
0.36
0.71
10
71
A
GLU
0.69
0.33
0.77
10
72
A
GLN
0.64
0.43
0.66
10
73
A
SER
0.80
0.36
0.68
10
74
A
GLU
0.91
0.33
0.55
10
84
A
GLN
0.73
0.43
0.52
9
86
A
GLY
0.88
0.41
0.59
7
87
A
GLY
0.85
0.41
0.67
9
89
A
ALA
0.51
0.38
0.60
9
92
A
GLY
0.78
0.41
0.68
1
93
A
LEU
0.74
0.70
0.64
4
94
A
THR
0.72
0.33
0.63
4
95
A
ARG
0.84
0.51
0.51
8
96
A
PHE
0.73
1.00
0.67
6
97
A
GLU
0.76
0.33
0.69
6
99
A
TRP
0.87
0.99
0.48
10
100
A
ASN
0.70
0.39
0.67
10
101
A
ILE
0.64
0.64
0.69
10
103
A
LYS
0.86
0.25
0.68
10
104
A
ALA
0.52
0.38
0.78
10
105
A
LEU
0.72
0.70
0.71
10
106
A
PRO
0.72
0.47
0.81
10
107
A
ASP
0.67
0.32
0.82
10
108
A
GLY
0.85
0.41
0.78
10
109
A
PRO
0.71
0.47
0.76
10
36
A
GLU
0.67
0.33
0.64
3
37
A
LYS
0.87
0.25
0.65
10
38
A
MET
0.79
0.66
0.78
10
39
A
SER
0.60
0.36
0.73
10
40
A
ALA
0.72
0.38
0.73
10
43
A
GLY
1.00
0.41
0.54
10
45
A
SER
0.89
0.36
0.48
2
47
A
GLU
0.75
0.33
0.52
4
48
A
GLY
0.94
0.41
0.55
1
49
A
GLY
0.90
0.41
0.64
1
50
A
LYS
0.67
0.25
0.75
1
51
A
GLY
0.75
0.41
0.73
2
52
A
SER
0.79
0.36
0.78
2
53
A
LEU
0.53
0.70
0.81
1
54
A
HIS
0.49
0.60
0.83
1
55
A
GLY
0.80
0.41
0.74
2
56
A
ASP
0.76
0.32
0.65
2
62
A
ASN
0.81
0.39
0.54
10
63
A
ARG
0.79
0.51
0.68
10
64
A
ILE
0.78
0.64
0.47
10
65
A
PHE
0.73
1.00
0.65
10
67
A
GLY
0.82
0.41
0.69
10
68
A
ALA
0.92
0.38
0.68
10
69
A
ALA
0.82
0.38
0.63
10
70
A
SER
0.92
0.36
0.61
10
71
A
GLU
0.69
0.33
0.67
10
72
A
GLN
0.64
0.43
0.54
10
73
A
SER
0.80
0.36
0.66
10
79
A
GLY
0.94
0.41
0.42
1
84
A
GLN
0.73
0.43
0.36
2
86
A
GLY
0.88
0.41
0.44
2
87
A
GLY
0.85
0.41
0.54
10
89
A
ALA
0.51
0.38
0.49
10
93
A
LEU
0.74
0.70
0.60
4
95
A
ARG
0.84
0.51
0.62
5
96
A
PHE
0.73
1.00
0.72
4
97
A
GLU
0.76
0.33
0.71
4
99
A
TRP
0.87
0.99
0.51
10
100
A
ASN
0.70
0.39
0.69
9
101
A
ILE
0.64
0.64
0.65
10
103
A
LYS
0.86
0.25
0.69
10
104
A
ALA
0.52
0.38
0.74
10
105
A
LEU
0.72
0.70
0.63
10
106
A
PRO
0.72
0.47
0.74
10
107
A
ASP
0.67
0.32
0.78
10
108
A
GLY
0.85
0.41
0.71
10
109
A
PRO
0.71
0.47
0.66
10
33
A
VAL
0.79
0.56
0.51
10
36
A
GLU
0.67
0.33
0.71
7
37
A
LYS
0.87
0.25
0.63
10
38
A
MET
0.79
0.66
0.79
10
39
A
SER
0.60
0.36
0.72
10
40
A
ALA
0.72
0.38
0.71
10
41
A
GLY
0.94
0.41
0.56
10
43
A
GLY
1.00
0.41
0.54
10
45
A
SER
0.89
0.36
0.36
9
63
A
ARG
0.79
0.51
0.60
10
64
A
ILE
0.78
0.64
0.48
10
65
A
PHE
0.73
1.00
0.62
10
66
A
LYS
0.75
0.25
0.78
10
67
A
GLY
0.82
0.41
0.75
10
68
A
ALA
0.92
0.38
0.76
10
69
A
ALA
0.82
0.38
0.64
10
70
A
SER
0.92
0.36
0.73
10
71
A
GLU
0.69
0.33
0.81
10
72
A
GLN
0.64
0.43
0.73
10
73
A
SER
0.80
0.36
0.76
10
74
A
GLU
0.91
0.33
0.67
10
76
A
VAL
0.82
0.56
0.48
10
78
A
PRO
0.64
0.47
0.49
8
84
A
GLN
0.73
0.43
0.35
6
86
A
GLY
0.88
0.41
0.45
3
87
A
GLY
0.85
0.41
0.49
10
89
A
ALA
0.51
0.38
0.36
4
93
A
LEU
0.74
0.70
0.39
1
96
A
PHE
0.73
1.00
0.55
1
99
A
TRP
0.87
0.99
0.36
10
100
A
ASN
0.70
0.39
0.54
10
101
A
ILE
0.64
0.64
0.49
10
103
A
LYS
0.86
0.25
0.59
10
104
A
ALA
0.52
0.38
0.66
10
105
A
LEU
0.72
0.70
0.59
10
106
A
PRO
0.72
0.47
0.72
10
107
A
ASP
0.67
0.32
0.78
10
108
A
GLY
0.85
0.41
0.74
10
109
A
PRO
0.71
0.47
0.72
10
37
A
LYS
0.87
0.25
0.59
10
38
A
MET
0.79
0.66
0.74
10
39
A
SER
0.60
0.36
0.77
10
40
A
ALA
0.72
0.38
0.71
10
41
A
GLY
0.94
0.41
0.60
10
45
A
SER
0.89
0.36
0.52
10
47
A
GLU
0.75
0.33
0.57
7
48
A
GLY
0.94
0.41
0.58
7
49
A
GLY
0.90
0.41
0.54
1
52
A
SER
0.79
0.36
0.61
3
53
A
LEU
0.53
0.70
0.69
3
54
A
HIS
0.49
0.60
0.77
3
55
A
GLY
0.80
0.41
0.74
3
56
A
ASP
0.76
0.32
0.69
3
57
A
LYS
0.70
0.25
0.64
2
58
A
PRO
0.84
0.47
0.48
1
62
A
ASN
0.81
0.39
0.60
10
63
A
ARG
0.79
0.51
0.73
10
64
A
ILE
0.78
0.64
0.56
10
65
A
PHE
0.73
1.00
0.70
10
66
A
LYS
0.75
0.25
0.73
10
67
A
GLY
0.82
0.41
0.61
10
68
A
ALA
0.92
0.38
0.67
10
69
A
ALA
0.82
0.38
0.58
5
70
A
SER
0.92
0.36
0.66
10
71
A
GLU
0.69
0.33
0.72
10
72
A
GLN
0.64
0.43
0.58
10
73
A
SER
0.80
0.36
0.68
10
74
A
GLU
0.91
0.33
0.64
10
76
A
VAL
0.82
0.56
0.45
10
78
A
PRO
0.64
0.47
0.59
10
79
A
GLY
0.94
0.41
0.51
10
87
A
GLY
0.85
0.41
0.38
8
89
A
ALA
0.51
0.38
0.27
7
91
A
GLN
0.65
0.43
0.32
1
94
A
THR
0.72
0.33
0.59
4
96
A
PHE
0.73
1.00
0.66
7
97
A
GLU
0.76
0.33
0.60
4
99
A
TRP
0.87
0.99
0.46
10
100
A
ASN
0.70
0.39
0.62
10
101
A
ILE
0.64
0.64
0.51
10
103
A
LYS
0.86
0.25
0.63
10
104
A
ALA
0.52
0.38
0.65
10
105
A
LEU
0.72
0.70
0.53
10
106
A
PRO
0.72
0.47
0.64
10
107
A
ASP
0.67
0.32
0.70
10
108
A
GLY
0.85
0.41
0.60
10
109
A
PRO
0.71
0.47
0.54
10
33
A
VAL
0.79
0.56
0.46
10
36
A
GLU
0.67
0.33
0.72
6
37
A
LYS
0.87
0.25
0.70
10
38
A
MET
0.79
0.66
0.80
10
39
A
SER
0.60
0.36
0.82
10
40
A
ALA
0.72
0.38
0.74
10
45
A
SER
0.89
0.36
0.42
1
47
A
GLU
0.75
0.33
0.39
5
48
A
GLY
0.94
0.41
0.41
4
62
A
ASN
0.81
0.39
0.39
9
63
A
ARG
0.79
0.51
0.59
10
64
A
ILE
0.78
0.64
0.44
10
65
A
PHE
0.73
1.00
0.62
10
66
A
LYS
0.75
0.25
0.71
10
67
A
GLY
0.82
0.41
0.73
10
68
A
ALA
0.92
0.38
0.67
10
69
A
ALA
0.82
0.38
0.66
6
70
A
SER
0.92
0.36
0.77
10
71
A
GLU
0.69
0.33
0.77
10
72
A
GLN
0.64
0.43
0.64
10
73
A
SER
0.80
0.36
0.68
10
74
A
GLU
0.91
0.33
0.58
10
78
A
PRO
0.64
0.47
0.37
9
79
A
GLY
0.94
0.41
0.22
7
84
A
GLN
0.73
0.43
0.45
6
86
A
GLY
0.88
0.41
0.56
8
87
A
GLY
0.85
0.41
0.61
10
89
A
ALA
0.51
0.38
0.51
2
93
A
LEU
0.74
0.70
0.59
2
95
A
ARG
0.84
0.51
0.50
7
96
A
PHE
0.73
1.00
0.64
2
97
A
GLU
0.76
0.33
0.68
2
99
A
TRP
0.87
0.99
0.47
10
100
A
ASN
0.70
0.39
0.66
9
101
A
ILE
0.64
0.64
0.67
9
103
A
LYS
0.86
0.25
0.68
10
104
A
ALA
0.52
0.38
0.77
10
105
A
LEU
0.72
0.70
0.71
10
106
A
PRO
0.72
0.47
0.80
10
107
A
ASP
0.67
0.32
0.82
10
108
A
GLY
0.85
0.41
0.77
10
109
A
PRO
0.71
0.47
0.74
10
33
A
VAL
0.79
0.56
0.39
10
36
A
GLU
0.67
0.33
0.69
3
37
A
LYS
0.87
0.25
0.62
7
38
A
MET
0.79
0.66
0.79
10
39
A
SER
0.60
0.36
0.79
10
40
A
ALA
0.72
0.38
0.72
10
41
A
GLY
0.94
0.41
0.62
10
63
A
ARG
0.79
0.51
0.66
10
64
A
ILE
0.78
0.64
0.50
10
65
A
PHE
0.73
1.00
0.67
10
66
A
LYS
0.75
0.25
0.76
10
67
A
GLY
0.82
0.41
0.73
10
68
A
ALA
0.92
0.38
0.62
10
69
A
ALA
0.82
0.38
0.66
10
70
A
SER
0.92
0.36
0.72
10
71
A
GLU
0.69
0.33
0.68
10
72
A
GLN
0.64
0.43
0.65
10
73
A
SER
0.80
0.36
0.71
10
74
A
GLU
0.91
0.33
0.56
10
76
A
VAL
0.82
0.56
0.42
8
78
A
PRO
0.64
0.47
0.46
1
84
A
GLN
0.73
0.43
0.38
8
86
A
GLY
0.88
0.41
0.51
1
87
A
GLY
0.85
0.41
0.57
10
89
A
ALA
0.51
0.38
0.49
9
93
A
LEU
0.74
0.70
0.61
1
94
A
THR
0.72
0.33
0.65
1
95
A
ARG
0.84
0.51
0.59
4
96
A
PHE
0.73
1.00
0.71
1
97
A
GLU
0.76
0.33
0.70
1
99
A
TRP
0.87
0.99
0.52
10
100
A
ASN
0.70
0.39
0.70
9
101
A
ILE
0.64
0.64
0.66
9
103
A
LYS
0.86
0.25
0.72
10
104
A
ALA
0.52
0.38
0.77
10
105
A
LEU
0.72
0.70
0.71
10
106
A
PRO
0.72
0.47
0.78
10
107
A
ASP
0.67
0.32
0.80
10
108
A
GLY
0.85
0.41
0.73
10
109
A
PRO
0.71
0.47
0.69
10
32
A
THR
0.62
0.33
0.25
10
33
A
VAL
0.79
0.56
0.21
10
34
A
THR
0.67
0.33
0.36
1
36
A
GLU
0.67
0.33
0.54
5
37
A
LYS
0.87
0.25
0.54
10
38
A
MET
0.79
0.66
0.67
10
39
A
SER
0.60
0.36
0.71
10
40
A
ALA
0.72
0.38
0.72
10
41
A
GLY
0.94
0.41
0.57
10
63
A
ARG
0.79
0.51
0.68
10
64
A
ILE
0.78
0.64
0.46
10
65
A
PHE
0.73
1.00
0.63
10
66
A
LYS
0.75
0.25
0.70
10
67
A
GLY
0.82
0.41
0.63
10
68
A
ALA
0.92
0.38
0.59
10
69
A
ALA
0.82
0.38
0.53
7
70
A
SER
0.92
0.36
0.54
10
71
A
GLU
0.69
0.33
0.63
10
72
A
GLN
0.64
0.43
0.47
10
73
A
SER
0.80
0.36
0.53
10
74
A
GLU
0.91
0.33
0.50
10
76
A
VAL
0.82
0.56
0.29
9
78
A
PRO
0.64
0.47
0.48
2
79
A
GLY
0.94
0.41
0.40
2
84
A
GLN
0.73
0.43
0.32
7
86
A
GLY
0.88
0.41
0.39
10
87
A
GLY
0.85
0.41
0.49
10
89
A
ALA
0.51
0.38
0.47
4
93
A
LEU
0.74
0.70
0.65
1
94
A
THR
0.72
0.33
0.69
2
95
A
ARG
0.84
0.51
0.64
2
96
A
PHE
0.73
1.00
0.71
10
97
A
GLU
0.76
0.33
0.71
2
99
A
TRP
0.87
0.99
0.50
10
100
A
ASN
0.70
0.39
0.68
10
101
A
ILE
0.64
0.64
0.63
10
103
A
LYS
0.86
0.25
0.67
10
104
A
ALA
0.52
0.38
0.72
10
105
A
LEU
0.72
0.70
0.63
10
106
A
PRO
0.72
0.47
0.70
10
107
A
ASP
0.67
0.32
0.71
10
108
A
GLY
0.85
0.41
0.61
10
109
A
PRO
0.71
0.47
0.54
10