Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1A3P chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
4
A
PRO
0.33
0.47
0.71
8
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.38
10
8
A
SER
0.50
0.36
0.58
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.21
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.43
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.31
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.41
10
23
A
ILE
0.36
0.64
0.24
10
24
A
GLU
0.49
0.33
0.51
10
25
A
SER
0.52
0.36
0.64
1
26
A
LEU
0.51
0.70
0.61
10
27
A
ASP
0.39
0.32
0.46
10
28
A
SER
0.39
0.36
0.21
10
29
A
TYR
0.68
0.80
0.10
10
30
A
THR
0.50
0.33
0.00
10
31
A
CYS
1.00
0.64
0.00
10
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.38
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.44
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.47
10
47
A
LEU
0.53
0.70
0.61
10
48
A
ARG
0.05
0.51
0.65
10
4
A
PRO
0.33
0.47
0.71
9
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.58
10
12
A
GLY
0.53
0.41
0.51
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.44
10
16
A
ASN
0.72
0.39
0.44
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.31
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.38
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.52
10
25
A
SER
0.52
0.36
0.65
5
26
A
LEU
0.51
0.70
0.62
6
27
A
ASP
0.39
0.32
0.47
9
28
A
SER
0.39
0.36
0.22
7
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.01
6
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.15
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.24
10
38
A
SER
0.47
0.36
0.39
10
39
A
GLY
1.00
0.41
0.53
10
40
A
ASP
0.53
0.32
0.26
10
41
A
ARG
0.85
0.51
0.33
10
43
A
GLN
0.72
0.43
0.47
10
44
A
THR
0.27
0.33
0.47
10
45
A
ARG
0.22
0.51
0.48
10
46
A
ASP
0.48
0.32
0.47
10
47
A
LEU
0.53
0.70
0.56
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.72
10
5
A
GLY
0.77
0.41
0.49
10
7
A
PRO
0.73
0.47
0.42
10
8
A
SER
0.50
0.36
0.62
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.44
10
16
A
ASN
0.72
0.39
0.44
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.52
10
21
A
MET
0.67
0.66
0.33
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.56
10
25
A
SER
0.52
0.36
0.66
4
26
A
LEU
0.51
0.70
0.61
5
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.25
10
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.00
5
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.57
10
37
A
TYR
0.73
0.80
0.24
10
38
A
SER
0.47
0.36
0.35
10
39
A
GLY
1.00
0.41
0.48
10
40
A
ASP
0.53
0.32
0.22
10
41
A
ARG
0.85
0.51
0.32
10
43
A
GLN
0.72
0.43
0.47
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.48
10
47
A
LEU
0.53
0.70
0.61
10
48
A
ARG
0.05
0.51
0.65
10
4
A
PRO
0.33
0.47
0.70
7
5
A
GLY
0.77
0.41
0.51
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.58
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.25
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.44
10
17
A
GLY
0.77
0.41
0.34
10
18
A
GLY
0.88
0.41
0.37
10
19
A
VAL
0.56
0.56
0.49
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.44
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.52
10
25
A
SER
0.52
0.36
0.65
2
26
A
LEU
0.51
0.70
0.61
3
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.21
5
29
A
TYR
0.68
0.80
0.12
10
30
A
THR
0.50
0.33
0.00
2
32
A
ASN
0.58
0.39
0.33
10
33
A
CYS
1.00
0.64
0.12
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.61
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.39
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.33
10
43
A
GLN
0.72
0.43
0.47
10
44
A
THR
0.27
0.33
0.49
9
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.46
10
47
A
LEU
0.53
0.70
0.55
10
48
A
ARG
0.05
0.51
0.66
10
4
A
PRO
0.33
0.47
0.72
4
5
A
GLY
0.77
0.41
0.50
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.56
10
9
A
SER
0.52
0.36
0.52
10
10
A
TYR
0.45
0.80
0.49
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.21
10
14
A
CYS
1.00
0.64
0.22
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.42
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.31
10
19
A
VAL
0.56
0.56
0.52
10
21
A
MET
0.67
0.66
0.34
10
22
A
HIS
0.45
0.60
0.39
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.51
10
25
A
SER
0.52
0.36
0.66
10
26
A
LEU
0.51
0.70
0.62
10
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.22
10
29
A
TYR
0.68
0.80
0.08
10
30
A
THR
0.50
0.33
0.00
9
31
A
CYS
1.00
0.64
0.00
10
32
A
ASN
0.58
0.39
0.37
10
33
A
CYS
1.00
0.64
0.16
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.61
10
37
A
TYR
0.73
0.80
0.22
10
38
A
SER
0.47
0.36
0.36
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.31
10
43
A
GLN
0.72
0.43
0.43
10
44
A
THR
0.27
0.33
0.44
10
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.45
10
47
A
LEU
0.53
0.70
0.55
10
48
A
ARG
0.05
0.51
0.66
10
4
A
PRO
0.33
0.47
0.72
6
5
A
GLY
0.77
0.41
0.50
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.52
10
11
A
ASP
0.43
0.32
0.64
10
12
A
GLY
0.53
0.41
0.50
10
13
A
TYR
0.70
0.80
0.19
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.43
10
16
A
ASN
0.72
0.39
0.44
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.30
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.41
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.51
10
25
A
SER
0.52
0.36
0.66
4
26
A
LEU
0.51
0.70
0.62
6
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.22
4
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.01
4
32
A
ASN
0.58
0.39
0.36
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.22
10
38
A
SER
0.47
0.36
0.38
9
39
A
GLY
1.00
0.41
0.53
10
40
A
ASP
0.53
0.32
0.29
9
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.46
10
47
A
LEU
0.53
0.70
0.55
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.69
8
5
A
GLY
0.77
0.41
0.50
10
7
A
PRO
0.73
0.47
0.38
10
8
A
SER
0.50
0.36
0.53
10
9
A
SER
0.52
0.36
0.49
10
10
A
TYR
0.45
0.80
0.49
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.41
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.49
9
26
A
LEU
0.51
0.70
0.62
4
27
A
ASP
0.39
0.32
0.48
10
28
A
SER
0.39
0.36
0.21
4
29
A
TYR
0.68
0.80
0.09
10
30
A
THR
0.50
0.33
0.00
4
32
A
ASN
0.58
0.39
0.36
10
33
A
CYS
1.00
0.64
0.14
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.24
10
38
A
SER
0.47
0.36
0.39
8
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.28
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.48
9
45
A
ARG
0.22
0.51
0.46
10
46
A
ASP
0.48
0.32
0.47
10
47
A
LEU
0.53
0.70
0.56
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.71
8
5
A
GLY
0.77
0.41
0.50
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.55
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.60
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.19
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.43
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.65
10
26
A
LEU
0.51
0.70
0.62
10
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.21
10
29
A
TYR
0.68
0.80
0.10
10
30
A
THR
0.50
0.33
0.00
10
31
A
CYS
1.00
0.64
0.00
10
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.11
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.22
10
38
A
SER
0.47
0.36
0.37
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.28
10
43
A
GLN
0.72
0.43
0.43
10
44
A
THR
0.27
0.33
0.47
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.48
10
47
A
LEU
0.53
0.70
0.63
10
48
A
ARG
0.05
0.51
0.62
10
4
A
PRO
0.33
0.47
0.71
7
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.54
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.61
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.21
10
14
A
CYS
1.00
0.64
0.23
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.41
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.39
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.49
10
25
A
SER
0.52
0.36
0.65
2
26
A
LEU
0.51
0.70
0.62
4
27
A
ASP
0.39
0.32
0.48
8
28
A
SER
0.39
0.36
0.22
3
29
A
TYR
0.68
0.80
0.09
10
30
A
THR
0.50
0.33
0.00
3
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.12
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.57
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.38
9
39
A
GLY
1.00
0.41
0.55
10
40
A
ASP
0.53
0.32
0.30
10
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.48
9
45
A
ARG
0.22
0.51
0.51
10
46
A
ASP
0.48
0.32
0.48
10
47
A
LEU
0.53
0.70
0.58
10
48
A
ARG
0.05
0.51
0.65
10
4
A
PRO
0.33
0.47
0.72
3
5
A
GLY
0.77
0.41
0.51
10
7
A
PRO
0.73
0.47
0.41
10
8
A
SER
0.50
0.36
0.59
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.57
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.26
10
15
A
LEU
0.79
0.70
0.45
10
16
A
ASN
0.72
0.39
0.45
10
17
A
GLY
0.77
0.41
0.38
10
18
A
GLY
0.88
0.41
0.27
10
19
A
VAL
0.56
0.56
0.50
10
21
A
MET
0.67
0.66
0.35
10
22
A
HIS
0.45
0.60
0.44
10
23
A
ILE
0.36
0.64
0.28
10
24
A
GLU
0.49
0.33
0.53
10
26
A
LEU
0.51
0.70
0.64
4
27
A
ASP
0.39
0.32
0.48
10
28
A
SER
0.39
0.36
0.23
7
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.04
4
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.14
10
34
A
VAL
0.50
0.56
0.41
10
35
A
ILE
0.37
0.64
0.61
10
37
A
TYR
0.73
0.80
0.25
10
38
A
SER
0.47
0.36
0.38
9
39
A
GLY
1.00
0.41
0.55
10
40
A
ASP
0.53
0.32
0.25
10
41
A
ARG
0.85
0.51
0.36
10
43
A
GLN
0.72
0.43
0.51
10
44
A
THR
0.27
0.33
0.46
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.47
10
47
A
LEU
0.53
0.70
0.61
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.71
8
5
A
GLY
0.77
0.41
0.49
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.58
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.60
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.25
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.42
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.33
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.52
10
26
A
LEU
0.51
0.70
0.62
4
27
A
ASP
0.39
0.32
0.47
9
28
A
SER
0.39
0.36
0.23
5
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.00
4
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.36
9
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.30
10
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.49
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.49
10
47
A
LEU
0.53
0.70
0.61
10
48
A
ARG
0.05
0.51
0.65
10
4
A
PRO
0.33
0.47
0.72
6
5
A
GLY
0.77
0.41
0.51
10
7
A
PRO
0.73
0.47
0.40
10
8
A
SER
0.50
0.36
0.60
10
9
A
SER
0.52
0.36
0.52
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.60
10
12
A
GLY
0.53
0.41
0.51
10
13
A
TYR
0.70
0.80
0.19
10
14
A
CYS
1.00
0.64
0.23
10
15
A
LEU
0.79
0.70
0.44
10
16
A
ASN
0.72
0.39
0.44
10
17
A
GLY
0.77
0.41
0.41
10
18
A
GLY
0.88
0.41
0.29
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.27
10
24
A
GLU
0.49
0.33
0.54
10
25
A
SER
0.52
0.36
0.66
1
26
A
LEU
0.51
0.70
0.65
3
27
A
ASP
0.39
0.32
0.50
10
28
A
SER
0.39
0.36
0.23
5
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.03
2
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.16
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.25
10
38
A
SER
0.47
0.36
0.37
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.26
10
41
A
ARG
0.85
0.51
0.35
10
43
A
GLN
0.72
0.43
0.50
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.49
10
47
A
LEU
0.53
0.70
0.62
10
48
A
ARG
0.05
0.51
0.65
10
4
A
PRO
0.33
0.47
0.72
5
5
A
GLY
0.77
0.41
0.53
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.59
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.58
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.22
10
14
A
CYS
1.00
0.64
0.23
10
15
A
LEU
0.79
0.70
0.43
10
16
A
ASN
0.72
0.39
0.42
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.30
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.65
1
26
A
LEU
0.51
0.70
0.62
4
27
A
ASP
0.39
0.32
0.48
9
28
A
SER
0.39
0.36
0.23
7
29
A
TYR
0.68
0.80
0.10
10
30
A
THR
0.50
0.33
0.02
4
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.16
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.62
10
37
A
TYR
0.73
0.80
0.24
10
38
A
SER
0.47
0.36
0.39
9
39
A
GLY
1.00
0.41
0.53
10
40
A
ASP
0.53
0.32
0.28
10
41
A
ARG
0.85
0.51
0.32
10
43
A
GLN
0.72
0.43
0.49
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.48
10
46
A
ASP
0.48
0.32
0.49
10
47
A
LEU
0.53
0.70
0.59
10
48
A
ARG
0.05
0.51
0.64
10
4
A
PRO
0.33
0.47
0.71
4
5
A
GLY
0.77
0.41
0.49
10
7
A
PRO
0.73
0.47
0.38
10
8
A
SER
0.50
0.36
0.55
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.61
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.19
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.42
10
16
A
ASN
0.72
0.39
0.41
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.52
10
21
A
MET
0.67
0.66
0.35
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.67
3
26
A
LEU
0.51
0.70
0.62
4
27
A
ASP
0.39
0.32
0.45
10
28
A
SER
0.39
0.36
0.20
6
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.00
3
32
A
ASN
0.58
0.39
0.37
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.37
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.22
10
38
A
SER
0.47
0.36
0.38
9
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.29
10
41
A
ARG
0.85
0.51
0.28
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.50
10
45
A
ARG
0.22
0.51
0.46
10
46
A
ASP
0.48
0.32
0.51
10
47
A
LEU
0.53
0.70
0.59
10
48
A
ARG
0.05
0.51
0.64
10
4
A
PRO
0.33
0.47
0.70
7
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.39
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.50
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.51
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.24
10
15
A
LEU
0.79
0.70
0.41
10
16
A
ASN
0.72
0.39
0.42
10
17
A
GLY
0.77
0.41
0.38
10
18
A
GLY
0.88
0.41
0.31
10
19
A
VAL
0.56
0.56
0.50
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.65
1
26
A
LEU
0.51
0.70
0.62
3
27
A
ASP
0.39
0.32
0.47
9
28
A
SER
0.39
0.36
0.20
3
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.01
2
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.15
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.62
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.40
8
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.28
10
41
A
ARG
0.85
0.51
0.31
10
43
A
GLN
0.72
0.43
0.50
10
44
A
THR
0.27
0.33
0.46
10
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.45
10
47
A
LEU
0.53
0.70
0.55
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.69
5
5
A
GLY
0.77
0.41
0.51
10
7
A
PRO
0.73
0.47
0.42
10
8
A
SER
0.50
0.36
0.63
10
9
A
SER
0.52
0.36
0.53
10
10
A
TYR
0.45
0.80
0.50
10
11
A
ASP
0.43
0.32
0.61
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.18
10
14
A
CYS
1.00
0.64
0.26
10
15
A
LEU
0.79
0.70
0.43
10
16
A
ASN
0.72
0.39
0.43
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.27
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.42
10
23
A
ILE
0.36
0.64
0.27
10
24
A
GLU
0.49
0.33
0.54
10
25
A
SER
0.52
0.36
0.68
10
26
A
LEU
0.51
0.70
0.62
10
27
A
ASP
0.39
0.32
0.47
10
28
A
SER
0.39
0.36
0.24
10
29
A
TYR
0.68
0.80
0.13
10
30
A
THR
0.50
0.33
0.00
9
31
A
CYS
1.00
0.64
0.02
10
32
A
ASN
0.58
0.39
0.37
10
33
A
CYS
1.00
0.64
0.15
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.60
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.38
10
39
A
GLY
1.00
0.41
0.54
10
40
A
ASP
0.53
0.32
0.27
10
41
A
ARG
0.85
0.51
0.30
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.47
10
45
A
ARG
0.22
0.51
0.49
10
46
A
ASP
0.48
0.32
0.46
10
47
A
LEU
0.53
0.70
0.59
10
48
A
ARG
0.05
0.51
0.68
10
4
A
PRO
0.33
0.47
0.67
10
5
A
GLY
0.77
0.41
0.54
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.49
10
10
A
TYR
0.45
0.80
0.49
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.50
10
13
A
TYR
0.70
0.80
0.15
10
14
A
CYS
1.00
0.64
0.26
10
15
A
LEU
0.79
0.70
0.43
10
16
A
ASN
0.72
0.39
0.45
10
17
A
GLY
0.77
0.41
0.37
10
18
A
GLY
0.88
0.41
0.27
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.41
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.26
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.67
1
26
A
LEU
0.51
0.70
0.63
7
27
A
ASP
0.39
0.32
0.50
10
28
A
SER
0.39
0.36
0.23
8
29
A
TYR
0.68
0.80
0.11
10
30
A
THR
0.50
0.33
0.00
7
32
A
ASN
0.58
0.39
0.34
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.38
10
35
A
ILE
0.37
0.64
0.57
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.36
10
39
A
GLY
1.00
0.41
0.49
10
40
A
ASP
0.53
0.32
0.24
10
41
A
ARG
0.85
0.51
0.34
10
43
A
GLN
0.72
0.43
0.48
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.50
10
46
A
ASP
0.48
0.32
0.48
10
47
A
LEU
0.53
0.70
0.61
10
48
A
ARG
0.05
0.51
0.64
10
4
A
PRO
0.33
0.47
0.70
6
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.54
10
9
A
SER
0.52
0.36
0.49
10
10
A
TYR
0.45
0.80
0.51
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.53
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.22
10
15
A
LEU
0.79
0.70
0.41
10
16
A
ASN
0.72
0.39
0.42
10
17
A
GLY
0.77
0.41
0.39
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.65
2
26
A
LEU
0.51
0.70
0.61
4
27
A
ASP
0.39
0.32
0.47
9
28
A
SER
0.39
0.36
0.21
6
29
A
TYR
0.68
0.80
0.09
10
30
A
THR
0.50
0.33
0.00
4
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.61
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.37
9
39
A
GLY
1.00
0.41
0.55
10
40
A
ASP
0.53
0.32
0.30
10
41
A
ARG
0.85
0.51
0.28
10
43
A
GLN
0.72
0.43
0.44
10
44
A
THR
0.27
0.33
0.47
10
45
A
ARG
0.22
0.51
0.47
10
46
A
ASP
0.48
0.32
0.48
10
47
A
LEU
0.53
0.70
0.59
10
48
A
ARG
0.05
0.51
0.63
10
4
A
PRO
0.33
0.47
0.70
9
5
A
GLY
0.77
0.41
0.52
10
7
A
PRO
0.73
0.47
0.36
10
8
A
SER
0.50
0.36
0.56
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.49
10
11
A
ASP
0.43
0.32
0.60
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.20
10
14
A
CYS
1.00
0.64
0.23
10
15
A
LEU
0.79
0.70
0.43
10
16
A
ASN
0.72
0.39
0.41
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.50
10
21
A
MET
0.67
0.66
0.40
10
22
A
HIS
0.45
0.60
0.40
10
23
A
ILE
0.36
0.64
0.25
10
24
A
GLU
0.49
0.33
0.48
10
25
A
SER
0.52
0.36
0.65
2
26
A
LEU
0.51
0.70
0.62
5
27
A
ASP
0.39
0.32
0.47
9
28
A
SER
0.39
0.36
0.20
4
29
A
TYR
0.68
0.80
0.09
10
30
A
THR
0.50
0.33
0.00
4
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.14
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.60
10
37
A
TYR
0.73
0.80
0.22
10
38
A
SER
0.47
0.36
0.38
10
39
A
GLY
1.00
0.41
0.55
10
40
A
ASP
0.53
0.32
0.30
10
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.45
10
44
A
THR
0.27
0.33
0.48
10
45
A
ARG
0.22
0.51
0.45
10
46
A
ASP
0.48
0.32
0.46
10
47
A
LEU
0.53
0.70
0.55
10
48
A
ARG
0.05
0.51
0.67
10
4
A
PRO
0.33
0.47
0.71
7
5
A
GLY
0.77
0.41
0.53
10
7
A
PRO
0.73
0.47
0.37
10
8
A
SER
0.50
0.36
0.57
10
9
A
SER
0.52
0.36
0.51
10
10
A
TYR
0.45
0.80
0.49
10
11
A
ASP
0.43
0.32
0.59
10
12
A
GLY
0.53
0.41
0.52
10
13
A
TYR
0.70
0.80
0.21
10
14
A
CYS
1.00
0.64
0.23
10
15
A
LEU
0.79
0.70
0.41
10
16
A
ASN
0.72
0.39
0.43
10
17
A
GLY
0.77
0.41
0.40
10
18
A
GLY
0.88
0.41
0.32
10
19
A
VAL
0.56
0.56
0.51
10
21
A
MET
0.67
0.66
0.39
10
22
A
HIS
0.45
0.60
0.39
10
23
A
ILE
0.36
0.64
0.24
10
24
A
GLU
0.49
0.33
0.50
10
25
A
SER
0.52
0.36
0.64
2
26
A
LEU
0.51
0.70
0.61
4
27
A
ASP
0.39
0.32
0.47
8
28
A
SER
0.39
0.36
0.22
3
29
A
TYR
0.68
0.80
0.09
10
30
A
THR
0.50
0.33
0.00
3
32
A
ASN
0.58
0.39
0.35
10
33
A
CYS
1.00
0.64
0.13
10
34
A
VAL
0.50
0.56
0.39
10
35
A
ILE
0.37
0.64
0.59
10
37
A
TYR
0.73
0.80
0.23
10
38
A
SER
0.47
0.36
0.37
9
39
A
GLY
1.00
0.41
0.55
10
40
A
ASP
0.53
0.32
0.30
10
41
A
ARG
0.85
0.51
0.29
10
43
A
GLN
0.72
0.43
0.43
10
44
A
THR
0.27
0.33
0.47
9
45
A
ARG
0.22
0.51
0.48
10
46
A
ASP
0.48
0.32
0.47
10
47
A
LEU
0.53
0.70
0.62
10
48
A
ARG
0.05
0.51
0.64
10