Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1AOY chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
10
A
LEU
0.72
0.70
0.32
10
17
A
LEU
0.66
0.70
0.25
10
20
A
GLU
0.49
0.33
0.52
10
23
A
PHE
0.73
1.00
0.39
10
24
A
SER
0.48
0.36
0.59
5
25
A
SER
0.80
0.36
0.55
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.58
10
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.60
10
32
A
ALA
0.57
0.38
0.47
10
34
A
GLN
0.54
0.43
0.63
10
35
A
GLU
0.22
0.33
0.69
10
36
A
GLN
0.34
0.43
0.55
10
37
A
GLY
0.91
0.41
0.65
10
38
A
PHE
0.71
1.00
0.51
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.66
10
41
A
ILE
0.73
0.64
0.45
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.53
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.62
10
49
A
MET
0.94
0.66
0.28
10
50
A
LEU
0.93
0.70
0.32
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.53
8
53
A
PHE
0.78
1.00
0.32
10
54
A
GLY
0.82
0.41
0.51
10
55
A
ALA
0.83
0.38
0.37
10
56
A
VAL
0.66
0.56
0.57
10
57
A
ARG
0.88
0.51
0.64
10
59
A
ARG
0.80
0.51
0.81
10
61
A
ALA
0.61
0.38
0.81
10
62
A
LYS
0.58
0.25
0.84
10
63
A
MET
0.83
0.66
0.87
10
64
A
GLU
0.53
0.33
0.76
10
65
A
MET
0.74
0.66
0.73
10
66
A
VAL
0.62
0.56
0.55
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.43
10
69
A
LEU
0.73
0.70
0.38
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.71
10
72
A
GLU
0.56
0.33
0.69
10
73
A
LEU
0.52
0.70
0.63
10
74
A
GLY
0.38
0.41
0.54
5
75
A
VAL
0.47
0.56
0.67
5
78
A
THR
0.09
0.33
0.72
8
7
A
GLN
0.60
0.43
0.63
3
10
A
LEU
0.72
0.70
0.35
10
23
A
PHE
0.73
1.00
0.39
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.58
10
28
A
GLU
0.72
0.33
0.59
10
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.60
10
32
A
ALA
0.57
0.38
0.46
10
34
A
GLN
0.54
0.43
0.65
10
35
A
GLU
0.22
0.33
0.67
10
36
A
GLN
0.34
0.43
0.56
10
37
A
GLY
0.91
0.41
0.66
10
38
A
PHE
0.71
1.00
0.53
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.73
10
41
A
ILE
0.73
0.64
0.51
10
42
A
ASN
0.91
0.39
0.66
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.55
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.60
10
49
A
MET
0.94
0.66
0.27
10
51
A
THR
0.65
0.33
0.58
10
54
A
GLY
0.82
0.41
0.50
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.62
10
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.70
7
61
A
ALA
0.61
0.38
0.80
10
62
A
LYS
0.58
0.25
0.81
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.74
6
65
A
MET
0.74
0.66
0.73
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.41
10
69
A
LEU
0.73
0.70
0.35
10
70
A
PRO
0.71
0.47
0.58
10
71
A
ALA
0.48
0.38
0.69
10
72
A
GLU
0.56
0.33
0.69
10
73
A
LEU
0.52
0.70
0.59
10
75
A
VAL
0.47
0.56
0.65
7
7
A
GLN
0.60
0.43
0.58
1
17
A
LEU
0.66
0.70
0.19
7
23
A
PHE
0.73
1.00
0.36
10
24
A
SER
0.48
0.36
0.57
1
25
A
SER
0.80
0.36
0.54
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.56
10
28
A
GLU
0.72
0.33
0.53
1
30
A
VAL
0.73
0.56
0.46
10
31
A
ALA
0.46
0.38
0.58
10
32
A
ALA
0.57
0.38
0.43
6
34
A
GLN
0.54
0.43
0.61
10
35
A
GLU
0.22
0.33
0.67
10
36
A
GLN
0.34
0.43
0.51
10
37
A
GLY
0.91
0.41
0.61
10
38
A
PHE
0.71
1.00
0.48
10
39
A
ASP
0.37
0.32
0.71
10
40
A
ASN
0.37
0.39
0.68
10
41
A
ILE
0.73
0.64
0.47
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.53
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.62
10
49
A
MET
0.94
0.66
0.27
10
50
A
LEU
0.93
0.70
0.30
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.54
6
53
A
PHE
0.78
1.00
0.34
10
54
A
GLY
0.82
0.41
0.51
10
55
A
ALA
0.83
0.38
0.39
10
56
A
VAL
0.66
0.56
0.57
10
57
A
ARG
0.88
0.51
0.64
10
59
A
ARG
0.80
0.51
0.80
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.75
10
65
A
MET
0.74
0.66
0.75
10
66
A
VAL
0.62
0.56
0.54
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.41
10
69
A
LEU
0.73
0.70
0.35
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.70
10
73
A
LEU
0.52
0.70
0.65
10
74
A
GLY
0.38
0.41
0.66
10
75
A
VAL
0.47
0.56
0.79
4
17
A
LEU
0.66
0.70
0.22
10
20
A
GLU
0.49
0.33
0.50
4
23
A
PHE
0.73
1.00
0.36
10
25
A
SER
0.80
0.36
0.54
10
26
A
GLN
0.97
0.43
0.48
10
27
A
GLY
0.58
0.41
0.55
10
28
A
GLU
0.72
0.33
0.55
2
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.60
10
32
A
ALA
0.57
0.38
0.46
9
34
A
GLN
0.54
0.43
0.64
10
35
A
GLU
0.22
0.33
0.69
10
36
A
GLN
0.34
0.43
0.56
10
37
A
GLY
0.91
0.41
0.67
10
38
A
PHE
0.71
1.00
0.53
10
39
A
ASP
0.37
0.32
0.75
10
40
A
ASN
0.37
0.39
0.70
10
41
A
ILE
0.73
0.64
0.48
10
42
A
ASN
0.91
0.39
0.66
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.55
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.63
10
49
A
MET
0.94
0.66
0.30
10
50
A
LEU
0.93
0.70
0.30
10
51
A
THR
0.65
0.33
0.58
10
52
A
LYS
0.75
0.25
0.51
10
53
A
PHE
0.78
1.00
0.30
10
54
A
GLY
0.82
0.41
0.47
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.55
10
57
A
ARG
0.88
0.51
0.62
10
59
A
ARG
0.80
0.51
0.81
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.83
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.74
10
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.38
10
68
A
CYS
0.62
0.64
0.40
10
69
A
LEU
0.73
0.70
0.33
10
70
A
PRO
0.71
0.47
0.56
10
71
A
ALA
0.48
0.38
0.68
10
72
A
GLU
0.56
0.33
0.62
1
73
A
LEU
0.52
0.70
0.60
10
23
A
PHE
0.73
1.00
0.38
10
24
A
SER
0.48
0.36
0.57
6
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.57
10
28
A
GLU
0.72
0.33
0.56
8
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.59
10
32
A
ALA
0.57
0.38
0.45
10
34
A
GLN
0.54
0.43
0.62
10
35
A
GLU
0.22
0.33
0.67
10
36
A
GLN
0.34
0.43
0.53
10
37
A
GLY
0.91
0.41
0.63
10
38
A
PHE
0.71
1.00
0.49
10
39
A
ASP
0.37
0.32
0.72
10
40
A
ASN
0.37
0.39
0.74
10
41
A
ILE
0.73
0.64
0.52
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.64
10
44
A
SER
0.89
0.36
0.68
10
45
A
LYS
0.94
0.25
0.56
10
47
A
SER
1.00
0.36
0.54
10
48
A
ARG
0.99
0.51
0.66
10
49
A
MET
0.94
0.66
0.35
10
50
A
LEU
0.93
0.70
0.32
10
51
A
THR
0.65
0.33
0.61
10
52
A
LYS
0.75
0.25
0.55
10
54
A
GLY
0.82
0.41
0.55
10
55
A
ALA
0.83
0.38
0.42
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.66
10
58
A
THR
0.62
0.33
0.65
3
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.68
2
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.81
10
63
A
MET
0.83
0.66
0.87
10
64
A
GLU
0.53
0.33
0.77
10
65
A
MET
0.74
0.66
0.74
10
66
A
VAL
0.62
0.56
0.54
10
67
A
TYR
0.98
0.80
0.40
10
69
A
LEU
0.73
0.70
0.36
10
70
A
PRO
0.71
0.47
0.61
10
71
A
ALA
0.48
0.38
0.71
10
72
A
GLU
0.56
0.33
0.59
9
73
A
LEU
0.52
0.70
0.63
10
74
A
GLY
0.38
0.41
0.63
2
75
A
VAL
0.47
0.56
0.66
2
17
A
LEU
0.66
0.70
0.24
10
20
A
GLU
0.49
0.33
0.51
5
23
A
PHE
0.73
1.00
0.39
10
24
A
SER
0.48
0.36
0.57
8
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.58
10
28
A
GLU
0.72
0.33
0.56
10
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.60
10
32
A
ALA
0.57
0.38
0.46
10
34
A
GLN
0.54
0.43
0.63
10
35
A
GLU
0.22
0.33
0.70
10
36
A
GLN
0.34
0.43
0.55
1
40
A
ASN
0.37
0.39
0.70
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.51
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.62
10
49
A
MET
0.94
0.66
0.25
10
50
A
LEU
0.93
0.70
0.32
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.55
3
54
A
GLY
0.82
0.41
0.52
10
55
A
ALA
0.83
0.38
0.38
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.64
10
58
A
THR
0.62
0.33
0.68
9
59
A
ARG
0.80
0.51
0.82
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.83
10
63
A
MET
0.83
0.66
0.85
10
64
A
GLU
0.53
0.33
0.74
10
65
A
MET
0.74
0.66
0.75
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.43
10
69
A
LEU
0.73
0.70
0.36
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.72
10
72
A
GLU
0.56
0.33
0.70
10
73
A
LEU
0.52
0.70
0.64
10
74
A
GLY
0.38
0.41
0.58
4
75
A
VAL
0.47
0.56
0.70
9
77
A
THR
0.23
0.33
0.74
3
7
A
GLN
0.60
0.43
0.59
10
16
A
ALA
0.60
0.38
0.35
6
20
A
GLU
0.49
0.33
0.51
8
24
A
SER
0.48
0.36
0.57
9
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.56
10
28
A
GLU
0.72
0.33
0.55
10
30
A
VAL
0.73
0.56
0.46
10
31
A
ALA
0.46
0.38
0.58
10
32
A
ALA
0.57
0.38
0.45
10
34
A
GLN
0.54
0.43
0.62
10
35
A
GLU
0.22
0.33
0.67
10
38
A
PHE
0.71
1.00
0.49
10
39
A
ASP
0.37
0.32
0.72
10
40
A
ASN
0.37
0.39
0.69
10
41
A
ILE
0.73
0.64
0.47
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.63
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.53
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.65
10
49
A
MET
0.94
0.66
0.27
10
51
A
THR
0.65
0.33
0.60
10
54
A
GLY
0.82
0.41
0.53
10
55
A
ALA
0.83
0.38
0.39
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.65
10
58
A
THR
0.62
0.33
0.64
10
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.68
10
61
A
ALA
0.61
0.38
0.79
10
62
A
LYS
0.58
0.25
0.82
5
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.75
10
65
A
MET
0.74
0.66
0.74
10
66
A
VAL
0.62
0.56
0.53
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.43
10
69
A
LEU
0.73
0.70
0.36
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.71
10
72
A
GLU
0.56
0.33
0.72
10
73
A
LEU
0.52
0.70
0.65
10
74
A
GLY
0.38
0.41
0.64
8
75
A
VAL
0.47
0.56
0.71
8
6
A
LYS
0.82
0.25
0.78
10
7
A
GLN
0.60
0.43
0.66
10
8
A
GLU
0.56
0.33
0.68
10
10
A
LEU
0.72
0.70
0.37
10
17
A
LEU
0.66
0.70
0.19
10
23
A
PHE
0.73
1.00
0.34
10
25
A
SER
0.80
0.36
0.52
10
26
A
GLN
0.97
0.43
0.47
10
27
A
GLY
0.58
0.41
0.54
10
28
A
GLU
0.72
0.33
0.52
1
30
A
VAL
0.73
0.56
0.44
10
31
A
ALA
0.46
0.38
0.56
10
34
A
GLN
0.54
0.43
0.61
10
35
A
GLU
0.22
0.33
0.65
10
38
A
PHE
0.71
1.00
0.50
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.75
10
41
A
ILE
0.73
0.64
0.52
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.62
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.40
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.64
10
49
A
MET
0.94
0.66
0.31
10
50
A
LEU
0.93
0.70
0.28
10
51
A
THR
0.65
0.33
0.58
10
52
A
LYS
0.75
0.25
0.53
7
54
A
GLY
0.82
0.41
0.47
10
55
A
ALA
0.83
0.38
0.33
10
56
A
VAL
0.66
0.56
0.53
10
57
A
ARG
0.88
0.51
0.61
10
58
A
THR
0.62
0.33
0.61
1
59
A
ARG
0.80
0.51
0.79
10
60
A
ASN
0.78
0.39
0.68
1
61
A
ALA
0.61
0.38
0.79
10
62
A
LYS
0.58
0.25
0.83
10
63
A
MET
0.83
0.66
0.84
10
64
A
GLU
0.53
0.33
0.72
10
65
A
MET
0.74
0.66
0.70
10
67
A
TYR
0.98
0.80
0.34
10
68
A
CYS
0.62
0.64
0.37
10
69
A
LEU
0.73
0.70
0.32
10
70
A
PRO
0.71
0.47
0.54
10
71
A
ALA
0.48
0.38
0.65
10
72
A
GLU
0.56
0.33
0.63
5
73
A
LEU
0.52
0.70
0.61
10
74
A
GLY
0.38
0.41
0.68
7
11
A
VAL
0.36
0.56
0.33
1
17
A
LEU
0.66
0.70
0.27
10
20
A
GLU
0.49
0.33
0.54
1
23
A
PHE
0.73
1.00
0.39
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.58
10
28
A
GLU
0.72
0.33
0.58
5
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.61
10
32
A
ALA
0.57
0.38
0.49
10
34
A
GLN
0.54
0.43
0.65
10
35
A
GLU
0.22
0.33
0.72
10
36
A
GLN
0.34
0.43
0.59
10
37
A
GLY
0.91
0.41
0.68
10
38
A
PHE
0.71
1.00
0.54
10
39
A
ASP
0.37
0.32
0.74
10
40
A
ASN
0.37
0.39
0.68
10
41
A
ILE
0.73
0.64
0.48
10
42
A
ASN
0.91
0.39
0.63
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.65
10
45
A
LYS
0.94
0.25
0.54
10
47
A
SER
1.00
0.36
0.51
10
48
A
ARG
0.99
0.51
0.61
10
49
A
MET
0.94
0.66
0.28
10
50
A
LEU
0.93
0.70
0.29
10
51
A
THR
0.65
0.33
0.56
10
52
A
LYS
0.75
0.25
0.49
6
53
A
PHE
0.78
1.00
0.28
10
54
A
GLY
0.82
0.41
0.45
10
55
A
ALA
0.83
0.38
0.31
10
56
A
VAL
0.66
0.56
0.54
10
57
A
ARG
0.88
0.51
0.62
10
59
A
ARG
0.80
0.51
0.80
10
61
A
ALA
0.61
0.38
0.80
10
62
A
LYS
0.58
0.25
0.83
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.73
1
65
A
MET
0.74
0.66
0.71
10
67
A
TYR
0.98
0.80
0.36
10
68
A
CYS
0.62
0.64
0.40
10
69
A
LEU
0.73
0.70
0.33
10
70
A
PRO
0.71
0.47
0.55
10
71
A
ALA
0.48
0.38
0.69
10
72
A
GLU
0.56
0.33
0.72
10
73
A
LEU
0.52
0.70
0.52
10
75
A
VAL
0.47
0.56
0.75
2
11
A
VAL
0.36
0.56
0.33
3
23
A
PHE
0.73
1.00
0.37
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.57
10
28
A
GLU
0.72
0.33
0.55
1
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.61
10
32
A
ALA
0.57
0.38
0.47
10
34
A
GLN
0.54
0.43
0.65
10
35
A
GLU
0.22
0.33
0.70
10
39
A
ASP
0.37
0.32
0.70
10
40
A
ASN
0.37
0.39
0.68
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.54
10
47
A
SER
1.00
0.36
0.52
10
48
A
ARG
0.99
0.51
0.63
10
49
A
MET
0.94
0.66
0.27
10
50
A
LEU
0.93
0.70
0.29
10
51
A
THR
0.65
0.33
0.58
10
52
A
LYS
0.75
0.25
0.52
7
53
A
PHE
0.78
1.00
0.31
10
54
A
GLY
0.82
0.41
0.48
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.55
10
57
A
ARG
0.88
0.51
0.63
10
59
A
ARG
0.80
0.51
0.80
10
60
A
ASN
0.78
0.39
0.69
1
61
A
ALA
0.61
0.38
0.80
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.75
10
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.37
10
68
A
CYS
0.62
0.64
0.39
10
69
A
LEU
0.73
0.70
0.30
10
70
A
PRO
0.71
0.47
0.55
10
71
A
ALA
0.48
0.38
0.67
10
73
A
LEU
0.52
0.70
0.62
10
74
A
GLY
0.38
0.41
0.66
8
75
A
VAL
0.47
0.56
0.73
8
17
A
LEU
0.66
0.70
0.26
10
20
A
GLU
0.49
0.33
0.52
5
24
A
SER
0.48
0.36
0.59
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.50
10
27
A
GLY
0.58
0.41
0.58
10
28
A
GLU
0.72
0.33
0.57
10
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.62
10
32
A
ALA
0.57
0.38
0.50
10
34
A
GLN
0.54
0.43
0.64
10
35
A
GLU
0.22
0.33
0.71
10
36
A
GLN
0.34
0.43
0.59
10
40
A
ASN
0.37
0.39
0.66
10
42
A
ASN
0.91
0.39
0.62
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.51
10
47
A
SER
1.00
0.36
0.51
10
48
A
ARG
0.99
0.51
0.61
10
49
A
MET
0.94
0.66
0.29
10
50
A
LEU
0.93
0.70
0.28
10
51
A
THR
0.65
0.33
0.57
10
52
A
LYS
0.75
0.25
0.51
3
54
A
GLY
0.82
0.41
0.50
10
55
A
ALA
0.83
0.38
0.36
10
56
A
VAL
0.66
0.56
0.56
10
57
A
ARG
0.88
0.51
0.66
10
58
A
THR
0.62
0.33
0.65
10
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.69
9
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.84
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.74
10
65
A
MET
0.74
0.66
0.74
10
66
A
VAL
0.62
0.56
0.54
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.42
10
69
A
LEU
0.73
0.70
0.35
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.69
10
72
A
GLU
0.56
0.33
0.69
9
73
A
LEU
0.52
0.70
0.59
10
74
A
GLY
0.38
0.41
0.53
4
75
A
VAL
0.47
0.56
0.66
3
7
A
GLN
0.60
0.43
0.61
10
17
A
LEU
0.66
0.70
0.20
10
20
A
GLU
0.49
0.33
0.49
9
23
A
PHE
0.73
1.00
0.36
10
24
A
SER
0.48
0.36
0.56
9
25
A
SER
0.80
0.36
0.54
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.57
10
28
A
GLU
0.72
0.33
0.54
7
30
A
VAL
0.73
0.56
0.48
10
31
A
ALA
0.46
0.38
0.58
10
34
A
GLN
0.54
0.43
0.62
10
35
A
GLU
0.22
0.33
0.67
10
36
A
GLN
0.34
0.43
0.51
10
37
A
GLY
0.91
0.41
0.64
10
38
A
PHE
0.71
1.00
0.52
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.75
10
41
A
ILE
0.73
0.64
0.53
10
42
A
ASN
0.91
0.39
0.66
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.68
10
45
A
LYS
0.94
0.25
0.41
10
47
A
SER
1.00
0.36
0.54
10
48
A
ARG
0.99
0.51
0.62
10
49
A
MET
0.94
0.66
0.30
10
50
A
LEU
0.93
0.70
0.31
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.54
4
54
A
GLY
0.82
0.41
0.50
10
55
A
ALA
0.83
0.38
0.38
10
56
A
VAL
0.66
0.56
0.57
10
57
A
ARG
0.88
0.51
0.65
10
59
A
ARG
0.80
0.51
0.80
10
61
A
ALA
0.61
0.38
0.77
10
62
A
LYS
0.58
0.25
0.84
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.73
9
65
A
MET
0.74
0.66
0.73
10
67
A
TYR
0.98
0.80
0.39
10
68
A
CYS
0.62
0.64
0.40
10
69
A
LEU
0.73
0.70
0.34
10
70
A
PRO
0.71
0.47
0.58
10
71
A
ALA
0.48
0.38
0.70
10
73
A
LEU
0.52
0.70
0.69
10
75
A
VAL
0.47
0.56
0.64
5
10
A
LEU
0.72
0.70
0.31
10
23
A
PHE
0.73
1.00
0.38
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.52
10
27
A
GLY
0.58
0.41
0.57
10
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.59
10
34
A
GLN
0.54
0.43
0.62
10
35
A
GLU
0.22
0.33
0.67
10
36
A
GLN
0.34
0.43
0.53
10
37
A
GLY
0.91
0.41
0.62
10
38
A
PHE
0.71
1.00
0.48
10
39
A
ASP
0.37
0.32
0.71
10
40
A
ASN
0.37
0.39
0.65
10
41
A
ILE
0.73
0.64
0.45
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.54
10
47
A
SER
1.00
0.36
0.54
10
48
A
ARG
0.99
0.51
0.64
10
49
A
MET
0.94
0.66
0.30
10
50
A
LEU
0.93
0.70
0.32
10
51
A
THR
0.65
0.33
0.61
10
52
A
LYS
0.75
0.25
0.55
7
54
A
GLY
0.82
0.41
0.52
10
55
A
ALA
0.83
0.38
0.40
10
56
A
VAL
0.66
0.56
0.59
10
57
A
ARG
0.88
0.51
0.64
10
58
A
THR
0.62
0.33
0.67
5
59
A
ARG
0.80
0.51
0.81
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.75
8
65
A
MET
0.74
0.66
0.76
10
67
A
TYR
0.98
0.80
0.41
10
69
A
LEU
0.73
0.70
0.34
10
70
A
PRO
0.71
0.47
0.56
10
71
A
ALA
0.48
0.38
0.68
10
72
A
GLU
0.56
0.33
0.72
10
73
A
LEU
0.52
0.70
0.65
10
75
A
VAL
0.47
0.56
0.59
2
6
A
LYS
0.82
0.25
0.73
10
7
A
GLN
0.60
0.43
0.62
10
17
A
LEU
0.66
0.70
0.16
10
23
A
PHE
0.73
1.00
0.33
10
25
A
SER
0.80
0.36
0.53
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.55
10
30
A
VAL
0.73
0.56
0.46
10
31
A
ALA
0.46
0.38
0.57
10
32
A
ALA
0.57
0.38
0.42
2
34
A
GLN
0.54
0.43
0.61
10
35
A
GLU
0.22
0.33
0.65
10
36
A
GLN
0.34
0.43
0.50
10
37
A
GLY
0.91
0.41
0.60
10
38
A
PHE
0.71
1.00
0.48
10
39
A
ASP
0.37
0.32
0.71
10
40
A
ASN
0.37
0.39
0.70
10
41
A
ILE
0.73
0.64
0.49
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.55
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.64
10
49
A
MET
0.94
0.66
0.31
10
50
A
LEU
0.93
0.70
0.30
10
51
A
THR
0.65
0.33
0.59
10
52
A
LYS
0.75
0.25
0.54
6
54
A
GLY
0.82
0.41
0.51
10
55
A
ALA
0.83
0.38
0.37
10
56
A
VAL
0.66
0.56
0.56
10
57
A
ARG
0.88
0.51
0.61
10
58
A
THR
0.62
0.33
0.65
2
59
A
ARG
0.80
0.51
0.80
10
60
A
ASN
0.78
0.39
0.66
3
61
A
ALA
0.61
0.38
0.77
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.85
10
64
A
GLU
0.53
0.33
0.72
8
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.36
10
68
A
CYS
0.62
0.64
0.40
10
69
A
LEU
0.73
0.70
0.35
10
70
A
PRO
0.71
0.47
0.58
10
71
A
ALA
0.48
0.38
0.71
10
72
A
GLU
0.56
0.33
0.64
10
73
A
LEU
0.52
0.70
0.56
10
75
A
VAL
0.47
0.56
0.74
3
17
A
LEU
0.66
0.70
0.26
10
23
A
PHE
0.73
1.00
0.38
10
24
A
SER
0.48
0.36
0.56
2
25
A
SER
0.80
0.36
0.54
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.56
10
28
A
GLU
0.72
0.33
0.55
6
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.61
10
34
A
GLN
0.54
0.43
0.64
10
35
A
GLU
0.22
0.33
0.71
10
36
A
GLN
0.34
0.43
0.58
10
37
A
GLY
0.91
0.41
0.69
10
38
A
PHE
0.71
1.00
0.55
10
39
A
ASP
0.37
0.32
0.74
10
40
A
ASN
0.37
0.39
0.72
10
41
A
ILE
0.73
0.64
0.51
10
42
A
ASN
0.91
0.39
0.63
10
43
A
GLN
1.00
0.43
0.62
10
44
A
SER
0.89
0.36
0.64
10
45
A
LYS
0.94
0.25
0.50
10
47
A
SER
1.00
0.36
0.49
10
48
A
ARG
0.99
0.51
0.61
10
49
A
MET
0.94
0.66
0.23
10
51
A
THR
0.65
0.33
0.55
9
52
A
LYS
0.75
0.25
0.49
8
53
A
PHE
0.78
1.00
0.30
10
54
A
GLY
0.82
0.41
0.45
10
55
A
ALA
0.83
0.38
0.32
10
56
A
VAL
0.66
0.56
0.54
10
57
A
ARG
0.88
0.51
0.61
10
59
A
ARG
0.80
0.51
0.80
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.82
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.75
10
65
A
MET
0.74
0.66
0.73
10
66
A
VAL
0.62
0.56
0.53
10
67
A
TYR
0.98
0.80
0.35
10
69
A
LEU
0.73
0.70
0.33
10
70
A
PRO
0.71
0.47
0.54
10
71
A
ALA
0.48
0.38
0.66
10
73
A
LEU
0.52
0.70
0.64
10
74
A
GLY
0.38
0.41
0.68
5
75
A
VAL
0.47
0.56
0.77
5
17
A
LEU
0.66
0.70
0.25
10
23
A
PHE
0.73
1.00
0.38
10
25
A
SER
0.80
0.36
0.54
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.59
10
28
A
GLU
0.72
0.33
0.56
2
30
A
VAL
0.73
0.56
0.49
10
31
A
ALA
0.46
0.38
0.61
10
32
A
ALA
0.57
0.38
0.48
10
34
A
GLN
0.54
0.43
0.65
10
36
A
GLN
0.34
0.43
0.59
1
40
A
ASN
0.37
0.39
0.68
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.54
10
47
A
SER
1.00
0.36
0.51
10
48
A
ARG
0.99
0.51
0.60
10
49
A
MET
0.94
0.66
0.31
10
51
A
THR
0.65
0.33
0.57
10
52
A
LYS
0.75
0.25
0.52
10
53
A
PHE
0.78
1.00
0.31
10
54
A
GLY
0.82
0.41
0.50
10
55
A
ALA
0.83
0.38
0.36
10
56
A
VAL
0.66
0.56
0.55
10
57
A
ARG
0.88
0.51
0.63
10
59
A
ARG
0.80
0.51
0.81
10
61
A
ALA
0.61
0.38
0.82
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.87
10
64
A
GLU
0.53
0.33
0.73
3
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.37
10
69
A
LEU
0.73
0.70
0.32
10
70
A
PRO
0.71
0.47
0.57
10
71
A
ALA
0.48
0.38
0.69
10
72
A
GLU
0.56
0.33
0.71
10
73
A
LEU
0.52
0.70
0.55
10
74
A
GLY
0.38
0.41
0.56
10
76
A
PRO
0.69
0.47
0.65
10
4
A
SER
0.37
0.36
0.73
10
17
A
LEU
0.66
0.70
0.24
10
23
A
PHE
0.73
1.00
0.38
10
25
A
SER
0.80
0.36
0.53
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.55
10
28
A
GLU
0.72
0.33
0.55
3
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.59
10
34
A
GLN
0.54
0.43
0.64
10
35
A
GLU
0.22
0.33
0.69
10
36
A
GLN
0.34
0.43
0.55
10
37
A
GLY
0.91
0.41
0.66
10
38
A
PHE
0.71
1.00
0.54
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.74
10
41
A
ILE
0.73
0.64
0.51
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.64
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.55
10
47
A
SER
1.00
0.36
0.51
10
48
A
ARG
0.99
0.51
0.64
10
49
A
MET
0.94
0.66
0.34
10
50
A
LEU
0.93
0.70
0.28
10
51
A
THR
0.65
0.33
0.58
10
52
A
LYS
0.75
0.25
0.53
6
54
A
GLY
0.82
0.41
0.48
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.56
10
57
A
ARG
0.88
0.51
0.62
10
58
A
THR
0.62
0.33
0.65
4
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.68
2
61
A
ALA
0.61
0.38
0.79
10
62
A
LYS
0.58
0.25
0.80
10
63
A
MET
0.83
0.66
0.85
10
64
A
GLU
0.53
0.33
0.74
9
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.37
10
68
A
CYS
0.62
0.64
0.40
10
69
A
LEU
0.73
0.70
0.32
10
70
A
PRO
0.71
0.47
0.55
10
71
A
ALA
0.48
0.38
0.66
10
73
A
LEU
0.52
0.70
0.60
10
7
A
GLN
0.60
0.43
0.60
5
17
A
LEU
0.66
0.70
0.25
10
23
A
PHE
0.73
1.00
0.34
10
25
A
SER
0.80
0.36
0.55
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.57
10
28
A
GLU
0.72
0.33
0.54
1
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.58
10
32
A
ALA
0.57
0.38
0.46
10
34
A
GLN
0.54
0.43
0.63
10
35
A
GLU
0.22
0.33
0.68
10
36
A
GLN
0.34
0.43
0.54
10
37
A
GLY
0.91
0.41
0.66
10
38
A
PHE
0.71
1.00
0.53
10
39
A
ASP
0.37
0.32
0.72
10
40
A
ASN
0.37
0.39
0.72
10
41
A
ILE
0.73
0.64
0.48
10
42
A
ASN
0.91
0.39
0.65
10
43
A
GLN
1.00
0.43
0.65
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.55
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.65
10
49
A
MET
0.94
0.66
0.28
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.55
10
53
A
PHE
0.78
1.00
0.34
10
54
A
GLY
0.82
0.41
0.52
10
55
A
ALA
0.83
0.38
0.37
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.62
10
58
A
THR
0.62
0.33
0.67
2
59
A
ARG
0.80
0.51
0.82
10
61
A
ALA
0.61
0.38
0.79
10
62
A
LYS
0.58
0.25
0.82
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.73
10
65
A
MET
0.74
0.66
0.73
10
67
A
TYR
0.98
0.80
0.38
10
68
A
CYS
0.62
0.64
0.42
10
69
A
LEU
0.73
0.70
0.34
10
70
A
PRO
0.71
0.47
0.58
10
71
A
ALA
0.48
0.38
0.70
10
72
A
GLU
0.56
0.33
0.58
5
73
A
LEU
0.52
0.70
0.65
10
74
A
GLY
0.38
0.41
0.66
10
75
A
VAL
0.47
0.56
0.69
5
4
A
SER
0.37
0.36
0.76
2
6
A
LYS
0.82
0.25
0.78
10
7
A
GLN
0.60
0.43
0.64
6
10
A
LEU
0.72
0.70
0.37
10
17
A
LEU
0.66
0.70
0.12
6
23
A
PHE
0.73
1.00
0.30
10
25
A
SER
0.80
0.36
0.53
10
26
A
GLN
0.97
0.43
0.48
10
30
A
VAL
0.73
0.56
0.44
10
34
A
GLN
0.54
0.43
0.60
10
35
A
GLU
0.22
0.33
0.64
10
38
A
PHE
0.71
1.00
0.49
10
39
A
ASP
0.37
0.32
0.72
10
40
A
ASN
0.37
0.39
0.74
10
41
A
ILE
0.73
0.64
0.51
10
42
A
ASN
0.91
0.39
0.66
10
43
A
GLN
1.00
0.43
0.64
10
44
A
SER
0.89
0.36
0.68
10
45
A
LYS
0.94
0.25
0.57
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.65
10
49
A
MET
0.94
0.66
0.30
10
51
A
THR
0.65
0.33
0.60
10
52
A
LYS
0.75
0.25
0.58
5
53
A
PHE
0.78
1.00
0.34
10
54
A
GLY
0.82
0.41
0.49
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.54
10
57
A
ARG
0.88
0.51
0.63
10
59
A
ARG
0.80
0.51
0.79
10
61
A
ALA
0.61
0.38
0.76
10
62
A
LYS
0.58
0.25
0.76
10
63
A
MET
0.83
0.66
0.85
10
65
A
MET
0.74
0.66
0.71
10
67
A
TYR
0.98
0.80
0.35
10
69
A
LEU
0.73
0.70
0.32
10
70
A
PRO
0.71
0.47
0.55
10
73
A
LEU
0.52
0.70
0.63
10
75
A
VAL
0.47
0.56
0.78
10
17
A
LEU
0.66
0.70
0.24
10
23
A
PHE
0.73
1.00
0.39
10
25
A
SER
0.80
0.36
0.56
10
26
A
GLN
0.97
0.43
0.51
10
27
A
GLY
0.58
0.41
0.58
10
28
A
GLU
0.72
0.33
0.56
3
30
A
VAL
0.73
0.56
0.47
10
31
A
ALA
0.46
0.38
0.60
10
32
A
ALA
0.57
0.38
0.46
9
34
A
GLN
0.54
0.43
0.63
10
35
A
GLU
0.22
0.33
0.69
10
36
A
GLN
0.34
0.43
0.53
10
37
A
GLY
0.91
0.41
0.63
10
38
A
PHE
0.71
1.00
0.50
10
39
A
ASP
0.37
0.32
0.73
10
40
A
ASN
0.37
0.39
0.66
10
41
A
ILE
0.73
0.64
0.47
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.66
10
44
A
SER
0.89
0.36
0.67
10
45
A
LYS
0.94
0.25
0.53
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.63
10
49
A
MET
0.94
0.66
0.27
10
50
A
LEU
0.93
0.70
0.33
10
51
A
THR
0.65
0.33
0.61
10
52
A
LYS
0.75
0.25
0.55
10
53
A
PHE
0.78
1.00
0.34
10
54
A
GLY
0.82
0.41
0.55
10
55
A
ALA
0.83
0.38
0.42
10
56
A
VAL
0.66
0.56
0.59
10
57
A
ARG
0.88
0.51
0.64
10
58
A
THR
0.62
0.33
0.67
7
59
A
ARG
0.80
0.51
0.82
10
61
A
ALA
0.61
0.38
0.79
10
62
A
LYS
0.58
0.25
0.81
10
63
A
MET
0.83
0.66
0.87
10
64
A
GLU
0.53
0.33
0.75
9
65
A
MET
0.74
0.66
0.76
10
67
A
TYR
0.98
0.80
0.41
10
69
A
LEU
0.73
0.70
0.34
10
70
A
PRO
0.71
0.47
0.59
10
71
A
ALA
0.48
0.38
0.67
10
72
A
GLU
0.56
0.33
0.61
10
73
A
LEU
0.52
0.70
0.60
10
75
A
VAL
0.47
0.56
0.71
1
7
A
GLN
0.60
0.43
0.60
10
17
A
LEU
0.66
0.70
0.21
10
20
A
GLU
0.49
0.33
0.50
7
23
A
PHE
0.73
1.00
0.35
10
24
A
SER
0.48
0.36
0.55
10
25
A
SER
0.80
0.36
0.53
10
26
A
GLN
0.97
0.43
0.49
10
27
A
GLY
0.58
0.41
0.54
10
28
A
GLU
0.72
0.33
0.52
2
30
A
VAL
0.73
0.56
0.44
10
31
A
ALA
0.46
0.38
0.56
10
32
A
ALA
0.57
0.38
0.42
10
34
A
GLN
0.54
0.43
0.59
10
35
A
GLU
0.22
0.33
0.65
10
36
A
GLN
0.34
0.43
0.51
10
40
A
ASN
0.37
0.39
0.70
10
42
A
ASN
0.91
0.39
0.62
10
43
A
GLN
1.00
0.43
0.62
10
44
A
SER
0.89
0.36
0.66
10
45
A
LYS
0.94
0.25
0.39
10
47
A
SER
1.00
0.36
0.53
10
48
A
ARG
0.99
0.51
0.62
10
49
A
MET
0.94
0.66
0.31
10
50
A
LEU
0.93
0.70
0.30
10
51
A
THR
0.65
0.33
0.61
10
54
A
GLY
0.82
0.41
0.54
10
55
A
ALA
0.83
0.38
0.40
10
56
A
VAL
0.66
0.56
0.58
10
57
A
ARG
0.88
0.51
0.64
10
59
A
ARG
0.80
0.51
0.81
10
60
A
ASN
0.78
0.39
0.70
3
61
A
ALA
0.61
0.38
0.80
10
62
A
LYS
0.58
0.25
0.83
10
63
A
MET
0.83
0.66
0.86
10
64
A
GLU
0.53
0.33
0.74
10
65
A
MET
0.74
0.66
0.72
10
67
A
TYR
0.98
0.80
0.38
10
68
A
CYS
0.62
0.64
0.42
10
69
A
LEU
0.73
0.70
0.37
10
70
A
PRO
0.71
0.47
0.60
10
71
A
ALA
0.48
0.38
0.72
10
72
A
GLU
0.56
0.33
0.64
10
73
A
LEU
0.52
0.70
0.66
10
74
A
GLY
0.38
0.41
0.67
1
75
A
VAL
0.47
0.56
0.79
1
6
A
LYS
0.82
0.25
0.77
10
7
A
GLN
0.60
0.43
0.67
10
8
A
GLU
0.56
0.33
0.65
1
10
A
LEU
0.72
0.70
0.33
10
11
A
VAL
0.36
0.56
0.40
10
24
A
SER
0.48
0.36
0.54
8
25
A
SER
0.80
0.36
0.52
10
26
A
GLN
0.97
0.43
0.46
10
27
A
GLY
0.58
0.41
0.55
10
28
A
GLU
0.72
0.33
0.52
8
30
A
VAL
0.73
0.56
0.44
10
31
A
ALA
0.46
0.38
0.58
10
32
A
ALA
0.57
0.38
0.45
4
34
A
GLN
0.54
0.43
0.62
10
35
A
GLU
0.22
0.33
0.67
10
40
A
ASN
0.37
0.39
0.72
10
42
A
ASN
0.91
0.39
0.64
10
43
A
GLN
1.00
0.43
0.63
10
44
A
SER
0.89
0.36
0.65
10
45
A
LYS
0.94
0.25
0.54
10
47
A
SER
1.00
0.36
0.50
10
48
A
ARG
0.99
0.51
0.64
10
49
A
MET
0.94
0.66
0.33
10
51
A
THR
0.65
0.33
0.55
10
52
A
LYS
0.75
0.25
0.53
10
53
A
PHE
0.78
1.00
0.32
10
54
A
GLY
0.82
0.41
0.44
10
55
A
ALA
0.83
0.38
0.32
10
56
A
VAL
0.66
0.56
0.52
10
57
A
ARG
0.88
0.51
0.61
10
58
A
THR
0.62
0.33
0.64
10
59
A
ARG
0.80
0.51
0.80
10
60
A
ASN
0.78
0.39
0.66
10
61
A
ALA
0.61
0.38
0.78
10
62
A
LYS
0.58
0.25
0.79
10
63
A
MET
0.83
0.66
0.85
10
64
A
GLU
0.53
0.33
0.73
10
65
A
MET
0.74
0.66
0.71
10
67
A
TYR
0.98
0.80
0.33
10
69
A
LEU
0.73
0.70
0.32
10
70
A
PRO
0.71
0.47
0.55
10
71
A
ALA
0.48
0.38
0.70
10
72
A
GLU
0.56
0.33
0.63
10
73
A
LEU
0.52
0.70
0.61
10
74
A
GLY
0.38
0.41
0.74
10
75
A
VAL
0.47
0.56
0.77
8
77
A
THR
0.23
0.33
0.81
8
78
A
THR
0.09
0.33
0.74
10
11
A
VAL
0.36
0.56
0.36
2
17
A
LEU
0.66
0.70
0.16
10
23
A
PHE
0.73
1.00
0.30
10
25
A
SER
0.80
0.36
0.52
10
26
A
GLN
0.97
0.43
0.47
10
27
A
GLY
0.58
0.41
0.54
10
28
A
GLU
0.72
0.33
0.50
2
30
A
VAL
0.73
0.56
0.43
10
31
A
ALA
0.46
0.38
0.56
10
34
A
GLN
0.54
0.43
0.60
10
35
A
GLU
0.22
0.33
0.66
10
36
A
GLN
0.34
0.43
0.52
10
37
A
GLY
0.91
0.41
0.63
10
38
A
PHE
0.71
1.00
0.49
10
39
A
ASP
0.37
0.32
0.72
10
40
A
ASN
0.37
0.39
0.66
10
41
A
ILE
0.73
0.64
0.46
10
42
A
ASN
0.91
0.39
0.62
10
43
A
GLN
1.00
0.43
0.64
10
44
A
SER
0.89
0.36
0.65
10
45
A
LYS
0.94
0.25
0.52
10
47
A
SER
1.00
0.36
0.51
10
48
A
ARG
0.99
0.51
0.63
10
49
A
MET
0.94
0.66
0.29
10
50
A
LEU
0.93
0.70
0.26
10
51
A
THR
0.65
0.33
0.59
10
52
A
LYS
0.75
0.25
0.55
10
53
A
PHE
0.78
1.00
0.37
10
54
A
GLY
0.82
0.41
0.51
10
55
A
ALA
0.83
0.38
0.35
10
56
A
VAL
0.66
0.56
0.53
10
57
A
ARG
0.88
0.51
0.59
10
58
A
THR
0.62
0.33
0.60
3
59
A
ARG
0.80
0.51
0.77
10
60
A
ASN
0.78
0.39
0.62
4
61
A
ALA
0.61
0.38
0.75
10
62
A
LYS
0.58
0.25
0.78
10
63
A
MET
0.83
0.66
0.83
10
65
A
MET
0.74
0.66
0.68
10
67
A
TYR
0.98
0.80
0.31
10
70
A
PRO
0.71
0.47
0.55
10
71
A
ALA
0.48
0.38
0.62
10
72
A
GLU
0.56
0.33
0.58
4
73
A
LEU
0.52
0.70
0.56
10
74
A
GLY
0.38
0.41
0.68
10
75
A
VAL
0.47
0.56
0.72
10