Pre-computed interfaces

How to use JET2 Viewer

References

Contact

JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1B22 chain A sc2

 

Download file

 

 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
16
A
GLU
0.10
0.33
0.66
3
18
A
GLU
0.17
0.33
0.53
8
22
A
PRO
0.57
0.47
0.53
1
24
A
PRO
0.47
0.47
0.44
10
26
A
SER
0.58
0.36
0.44
10
27
A
ARG
0.43
0.51
0.62
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.44
10
34
A
ASN
0.61
0.39
0.55
10
35
A
ALA
0.53
0.38
0.53
10
37
A
ASP
0.93
0.32
0.47
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.55
10
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.54
10
44
A
ALA
0.54
0.38
0.60
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.33
10
47
A
HIS
0.47
0.60
0.43
10
48
A
THR
0.87
0.33
0.40
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.44
10
52
A
VAL
0.62
0.56
0.46
10
53
A
ALA
0.81
0.38
0.58
10
54
A
TYR
0.64
0.80
0.70
10
55
A
ALA
0.67
0.38
0.56
10
56
A
PRO
0.77
0.47
0.55
10
58
A
LYS
0.59
0.25
0.59
9
59
A
GLU
0.50
0.33
0.59
10
60
A
LEU
0.91
0.70
0.27
10
61
A
ILE
0.35
0.64
0.38
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.57
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.51
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.33
10
73
A
LYS
0.88
0.25
0.48
10
75
A
LEU
0.65
0.70
0.24
7
77
A
GLU
0.74
0.33
0.49
9
80
A
LYS
0.73
0.25
0.65
7
81
A
LEU
0.49
0.70
0.62
10
82
A
VAL
0.57
0.56
0.50
10
83
A
PRO
0.52
0.47
0.65
3
84
A
MET
0.44
0.66
0.72
1
85
A
GLY
0.62
0.41
0.76
1
16
A
GLU
0.10
0.33
0.68
10
17
A
GLU
0.15
0.33
0.57
2
20
A
PHE
0.22
1.00
0.64
3
21
A
GLY
0.47
0.41
0.59
3
23
A
GLN
0.41
0.43
0.54
10
24
A
PRO
0.47
0.47
0.50
10
26
A
SER
0.58
0.36
0.45
10
27
A
ARG
0.43
0.51
0.64
10
28
A
LEU
0.86
0.70
0.41
10
30
A
GLN
0.50
0.43
0.51
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.37
10
34
A
ASN
0.61
0.39
0.50
10
35
A
ALA
0.53
0.38
0.51
10
37
A
ASP
0.93
0.32
0.42
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.55
10
41
A
LEU
0.88
0.70
0.41
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.62
10
44
A
ALA
0.54
0.38
0.57
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.49
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.51
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.36
10
53
A
ALA
0.81
0.38
0.59
10
54
A
TYR
0.64
0.80
0.63
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.61
10
60
A
LEU
0.91
0.70
0.28
10
62
A
ASN
0.47
0.39
0.62
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.67
10
65
A
GLY
0.92
0.41
0.66
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.53
10
70
A
LYS
0.93
0.25
0.44
10
73
A
LYS
0.88
0.25
0.46
10
75
A
LEU
0.65
0.70
0.15
10
77
A
GLU
0.74
0.33
0.47
10
79
A
ALA
0.58
0.38
0.45
10
80
A
LYS
0.73
0.25
0.63
10
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.50
10
83
A
PRO
0.52
0.47
0.60
10
84
A
MET
0.44
0.66
0.72
3
85
A
GLY
0.62
0.41
0.78
3
16
A
GLU
0.10
0.33
0.65
1
17
A
GLU
0.15
0.33
0.62
10
22
A
PRO
0.57
0.47
0.46
6
23
A
GLN
0.41
0.43
0.55
10
24
A
PRO
0.47
0.47
0.50
10
26
A
SER
0.58
0.36
0.45
10
27
A
ARG
0.43
0.51
0.61
10
28
A
LEU
0.86
0.70
0.37
10
30
A
GLN
0.50
0.43
0.53
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.52
10
37
A
ASP
0.93
0.32
0.46
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.58
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.48
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.51
10
50
A
GLU
0.77
0.33
0.44
10
52
A
VAL
0.62
0.56
0.39
10
53
A
ALA
0.81
0.38
0.56
10
54
A
TYR
0.64
0.80
0.68
10
55
A
ALA
0.67
0.38
0.56
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.62
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.57
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.52
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.54
10
70
A
LYS
0.93
0.25
0.43
10
73
A
LYS
0.88
0.25
0.47
10
75
A
LEU
0.65
0.70
0.22
10
77
A
GLU
0.74
0.33
0.47
10
79
A
ALA
0.58
0.38
0.47
5
80
A
LYS
0.73
0.25
0.65
5
81
A
LEU
0.49
0.70
0.58
10
82
A
VAL
0.57
0.56
0.48
10
83
A
PRO
0.52
0.47
0.62
6
84
A
MET
0.44
0.66
0.75
1
85
A
GLY
0.62
0.41
0.77
1
17
A
GLU
0.15
0.33
0.56
7
19
A
SER
0.16
0.36
0.54
4
23
A
GLN
0.41
0.43
0.56
10
24
A
PRO
0.47
0.47
0.53
10
26
A
SER
0.58
0.36
0.45
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.38
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.42
10
34
A
ASN
0.61
0.39
0.54
10
35
A
ALA
0.53
0.38
0.53
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.61
10
41
A
LEU
0.88
0.70
0.48
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.59
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.50
10
48
A
THR
0.87
0.33
0.47
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.48
10
52
A
VAL
0.62
0.56
0.46
10
53
A
ALA
0.81
0.38
0.63
10
54
A
TYR
0.64
0.80
0.63
10
55
A
ALA
0.67
0.38
0.52
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.62
10
60
A
LEU
0.91
0.70
0.30
10
62
A
ASN
0.47
0.39
0.66
10
63
A
ILE
0.61
0.64
0.58
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.55
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.53
9
70
A
LYS
0.93
0.25
0.44
10
73
A
LYS
0.88
0.25
0.44
10
75
A
LEU
0.65
0.70
0.20
10
76
A
ALA
0.49
0.38
0.42
4
77
A
GLU
0.74
0.33
0.40
3
81
A
LEU
0.49
0.70
0.63
10
82
A
VAL
0.57
0.56
0.50
10
16
A
GLU
0.10
0.33
0.71
10
17
A
GLU
0.15
0.33
0.57
10
23
A
GLN
0.41
0.43
0.53
10
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.41
10
27
A
ARG
0.43
0.51
0.60
10
28
A
LEU
0.86
0.70
0.34
10
30
A
GLN
0.50
0.43
0.53
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.57
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.51
10
37
A
ASP
0.93
0.32
0.49
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.39
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.56
10
44
A
ALA
0.54
0.38
0.59
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.32
10
47
A
HIS
0.47
0.60
0.44
10
48
A
THR
0.87
0.33
0.40
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.39
10
52
A
VAL
0.62
0.56
0.36
10
53
A
ALA
0.81
0.38
0.52
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.52
10
56
A
PRO
0.77
0.47
0.57
10
58
A
LYS
0.59
0.25
0.61
10
59
A
GLU
0.50
0.33
0.60
10
62
A
ASN
0.47
0.39
0.63
10
63
A
ILE
0.61
0.64
0.55
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.66
10
66
A
ILE
0.70
0.64
0.51
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.52
10
73
A
LYS
0.88
0.25
0.45
10
76
A
ALA
0.49
0.38
0.45
8
77
A
GLU
0.74
0.33
0.45
9
79
A
ALA
0.58
0.38
0.48
9
80
A
LYS
0.73
0.25
0.66
8
81
A
LEU
0.49
0.70
0.60
9
82
A
VAL
0.57
0.56
0.49
9
83
A
PRO
0.52
0.47
0.64
7
16
A
GLU
0.10
0.33
0.68
10
23
A
GLN
0.41
0.43
0.32
10
24
A
PRO
0.47
0.47
0.46
10
26
A
SER
0.58
0.36
0.46
10
27
A
ARG
0.43
0.51
0.61
10
28
A
LEU
0.86
0.70
0.35
10
30
A
GLN
0.50
0.43
0.54
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.57
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.40
10
35
A
ALA
0.53
0.38
0.50
10
37
A
ASP
0.93
0.32
0.49
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.48
9
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.55
10
44
A
ALA
0.54
0.38
0.57
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.45
10
48
A
THR
0.87
0.33
0.42
10
49
A
VAL
0.56
0.56
0.50
10
50
A
GLU
0.77
0.33
0.43
10
52
A
VAL
0.62
0.56
0.44
10
53
A
ALA
0.81
0.38
0.59
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.51
10
56
A
PRO
0.77
0.47
0.54
10
58
A
LYS
0.59
0.25
0.60
10
59
A
GLU
0.50
0.33
0.57
10
62
A
ASN
0.47
0.39
0.63
10
63
A
ILE
0.61
0.64
0.56
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.66
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.51
10
68
A
GLU
0.81
0.33
0.50
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.44
10
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.43
8
77
A
GLU
0.74
0.33
0.46
10
79
A
ALA
0.58
0.38
0.46
8
80
A
LYS
0.73
0.25
0.66
8
81
A
LEU
0.49
0.70
0.58
10
82
A
VAL
0.57
0.56
0.48
10
83
A
PRO
0.52
0.47
0.59
8
16
A
GLU
0.10
0.33
0.67
1
17
A
GLU
0.15
0.33
0.66
10
19
A
SER
0.16
0.36
0.54
1
20
A
PHE
0.22
1.00
0.57
1
21
A
GLY
0.47
0.41
0.60
8
22
A
PRO
0.57
0.47
0.59
10
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.49
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.35
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.57
10
33
A
ILE
0.76
0.64
0.37
10
34
A
ASN
0.61
0.39
0.51
10
35
A
ALA
0.53
0.38
0.49
10
37
A
ASP
0.93
0.32
0.46
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.50
10
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.56
10
44
A
ALA
0.54
0.38
0.58
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.44
10
48
A
THR
0.87
0.33
0.43
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.45
10
52
A
VAL
0.62
0.56
0.44
10
53
A
ALA
0.81
0.38
0.64
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.57
10
57
A
LYS
0.67
0.25
0.38
1
58
A
LYS
0.59
0.25
0.62
10
59
A
GLU
0.50
0.33
0.60
10
60
A
LEU
0.91
0.70
0.30
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.57
10
64
A
LYS
0.88
0.25
0.68
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.51
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.54
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.42
10
73
A
LYS
0.88
0.25
0.46
10
75
A
LEU
0.65
0.70
0.24
10
77
A
GLU
0.74
0.33
0.45
10
79
A
ALA
0.58
0.38
0.48
9
80
A
LYS
0.73
0.25
0.67
5
81
A
LEU
0.49
0.70
0.57
10
82
A
VAL
0.57
0.56
0.45
10
83
A
PRO
0.52
0.47
0.61
6
84
A
MET
0.44
0.66
0.74
3
85
A
GLY
0.62
0.41
0.68
7
16
A
GLU
0.10
0.33
0.66
10
17
A
GLU
0.15
0.33
0.58
9
24
A
PRO
0.47
0.47
0.47
10
26
A
SER
0.58
0.36
0.48
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.54
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.39
10
34
A
ASN
0.61
0.39
0.51
10
35
A
ALA
0.53
0.38
0.50
10
37
A
ASP
0.93
0.32
0.46
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.52
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.53
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.50
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.48
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.50
10
50
A
GLU
0.77
0.33
0.47
10
52
A
VAL
0.62
0.56
0.47
10
53
A
ALA
0.81
0.38
0.64
10
54
A
TYR
0.64
0.80
0.64
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.58
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.60
10
60
A
LEU
0.91
0.70
0.29
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.58
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.52
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.52
9
73
A
LYS
0.88
0.25
0.46
10
75
A
LEU
0.65
0.70
0.22
7
77
A
GLU
0.74
0.33
0.46
5
79
A
ALA
0.58
0.38
0.46
3
80
A
LYS
0.73
0.25
0.64
4
81
A
LEU
0.49
0.70
0.59
10
82
A
VAL
0.57
0.56
0.48
10
83
A
PRO
0.52
0.47
0.61
4
84
A
MET
0.44
0.66
0.73
3
85
A
GLY
0.62
0.41
0.78
2
16
A
GLU
0.10
0.33
0.62
10
17
A
GLU
0.15
0.33
0.63
10
23
A
GLN
0.41
0.43
0.47
10
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.45
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.37
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.64
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.44
10
34
A
ASN
0.61
0.39
0.55
10
35
A
ALA
0.53
0.38
0.54
10
37
A
ASP
0.93
0.32
0.50
10
38
A
VAL
0.66
0.56
0.62
10
39
A
LYS
0.61
0.25
0.51
9
41
A
LEU
0.88
0.70
0.49
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.60
10
44
A
ALA
0.54
0.38
0.59
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.46
10
48
A
THR
0.87
0.33
0.42
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.48
10
52
A
VAL
0.62
0.56
0.39
10
53
A
ALA
0.81
0.38
0.60
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.58
10
56
A
PRO
0.77
0.47
0.60
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.62
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.53
10
64
A
LYS
0.88
0.25
0.71
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.52
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.53
10
70
A
LYS
0.93
0.25
0.43
10
73
A
LYS
0.88
0.25
0.45
10
76
A
ALA
0.49
0.38
0.43
9
77
A
GLU
0.74
0.33
0.49
9
79
A
ALA
0.58
0.38
0.48
9
80
A
LYS
0.73
0.25
0.67
9
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.49
10
83
A
PRO
0.52
0.47
0.64
6
18
A
GLU
0.17
0.33
0.53
10
19
A
SER
0.16
0.36
0.50
7
20
A
PHE
0.22
1.00
0.66
7
21
A
GLY
0.47
0.41
0.50
7
22
A
PRO
0.57
0.47
0.40
10
23
A
GLN
0.41
0.43
0.53
10
24
A
PRO
0.47
0.47
0.52
10
26
A
SER
0.58
0.36
0.44
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.33
10
30
A
GLN
0.50
0.43
0.54
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.41
10
34
A
ASN
0.61
0.39
0.55
10
35
A
ALA
0.53
0.38
0.53
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.62
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.62
10
43
A
GLU
0.59
0.33
0.45
10
44
A
ALA
0.54
0.38
0.58
10
45
A
GLY
0.95
0.41
0.49
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.38
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.47
10
50
A
GLU
0.77
0.33
0.40
10
53
A
ALA
0.81
0.38
0.58
10
54
A
TYR
0.64
0.80
0.60
10
55
A
ALA
0.67
0.38
0.52
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.62
10
62
A
ASN
0.47
0.39
0.66
10
63
A
ILE
0.61
0.64
0.59
10
64
A
LYS
0.88
0.25
0.67
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.54
10
69
A
ALA
0.53
0.38
0.53
10
73
A
LYS
0.88
0.25
0.47
10
75
A
LEU
0.65
0.70
0.23
10
76
A
ALA
0.49
0.38
0.46
9
77
A
GLU
0.74
0.33
0.48
10
79
A
ALA
0.58
0.38
0.48
8
80
A
LYS
0.73
0.25
0.66
10
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.50
10
83
A
PRO
0.52
0.47
0.64
10
84
A
MET
0.44
0.66
0.73
1
85
A
GLY
0.62
0.41
0.71
1
16
A
GLU
0.10
0.33
0.66
10
17
A
GLU
0.15
0.33
0.60
10
22
A
PRO
0.57
0.47
0.55
1
24
A
PRO
0.47
0.47
0.47
10
26
A
SER
0.58
0.36
0.51
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.38
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.62
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.41
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.48
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.50
9
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.62
10
43
A
GLU
0.59
0.33
0.57
10
44
A
ALA
0.54
0.38
0.50
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.40
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.47
10
52
A
VAL
0.62
0.56
0.44
10
53
A
ALA
0.81
0.38
0.59
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.54
10
56
A
PRO
0.77
0.47
0.57
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.60
10
60
A
LEU
0.91
0.70
0.29
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.66
10
66
A
ILE
0.70
0.64
0.49
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.51
10
70
A
LYS
0.93
0.25
0.39
10
73
A
LYS
0.88
0.25
0.44
10
75
A
LEU
0.65
0.70
0.28
10
76
A
ALA
0.49
0.38
0.46
4
77
A
GLU
0.74
0.33
0.46
6
79
A
ALA
0.58
0.38
0.47
3
80
A
LYS
0.73
0.25
0.66
3
81
A
LEU
0.49
0.70
0.62
10
82
A
VAL
0.57
0.56
0.49
10
83
A
PRO
0.52
0.47
0.66
2
84
A
MET
0.44
0.66
0.66
1
85
A
GLY
0.62
0.41
0.75
1
17
A
GLU
0.15
0.33
0.66
10
18
A
GLU
0.17
0.33
0.55
2
23
A
GLN
0.41
0.43
0.51
10
24
A
PRO
0.47
0.47
0.52
10
26
A
SER
0.58
0.36
0.53
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.57
10
31
A
CYS
0.59
0.64
0.65
10
32
A
GLY
0.94
0.41
0.61
10
33
A
ILE
0.76
0.64
0.43
10
34
A
ASN
0.61
0.39
0.55
10
35
A
ALA
0.53
0.38
0.54
10
37
A
ASP
0.93
0.32
0.49
10
38
A
VAL
0.66
0.56
0.62
10
39
A
LYS
0.61
0.25
0.51
10
41
A
LEU
0.88
0.70
0.48
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.58
10
44
A
ALA
0.54
0.38
0.59
10
45
A
GLY
0.95
0.41
0.53
10
46
A
PHE
0.57
1.00
0.37
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.53
10
49
A
VAL
0.56
0.56
0.53
10
50
A
GLU
0.77
0.33
0.49
10
52
A
VAL
0.62
0.56
0.43
10
53
A
ALA
0.81
0.38
0.62
10
54
A
TYR
0.64
0.80
0.49
10
55
A
ALA
0.67
0.38
0.59
10
56
A
PRO
0.77
0.47
0.63
10
57
A
LYS
0.67
0.25
0.48
1
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.64
10
62
A
ASN
0.47
0.39
0.68
10
63
A
ILE
0.61
0.64
0.59
10
64
A
LYS
0.88
0.25
0.72
10
65
A
GLY
0.92
0.41
0.69
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.55
10
68
A
GLU
0.81
0.33
0.54
10
69
A
ALA
0.53
0.38
0.52
10
73
A
LYS
0.88
0.25
0.44
9
75
A
LEU
0.65
0.70
0.26
10
76
A
ALA
0.49
0.38
0.45
4
77
A
GLU
0.74
0.33
0.48
10
79
A
ALA
0.58
0.38
0.49
9
80
A
LYS
0.73
0.25
0.65
10
81
A
LEU
0.49
0.70
0.62
10
82
A
VAL
0.57
0.56
0.49
10
83
A
PRO
0.52
0.47
0.64
5
84
A
MET
0.44
0.66
0.76
4
85
A
GLY
0.62
0.41
0.74
7
16
A
GLU
0.10
0.33
0.72
10
17
A
GLU
0.15
0.33
0.62
9
24
A
PRO
0.47
0.47
0.51
10
26
A
SER
0.58
0.36
0.51
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.65
10
32
A
GLY
0.94
0.41
0.62
10
33
A
ILE
0.76
0.64
0.45
10
34
A
ASN
0.61
0.39
0.58
10
35
A
ALA
0.53
0.38
0.54
10
37
A
ASP
0.93
0.32
0.50
10
38
A
VAL
0.66
0.56
0.63
10
39
A
LYS
0.61
0.25
0.55
10
41
A
LEU
0.88
0.70
0.49
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.58
10
44
A
ALA
0.54
0.38
0.60
10
45
A
GLY
0.95
0.41
0.53
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.54
10
50
A
GLU
0.77
0.33
0.44
9
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.62
10
54
A
TYR
0.64
0.80
0.70
10
55
A
ALA
0.67
0.38
0.52
9
56
A
PRO
0.77
0.47
0.58
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.62
10
60
A
LEU
0.91
0.70
0.31
10
62
A
ASN
0.47
0.39
0.66
10
63
A
ILE
0.61
0.64
0.59
10
64
A
LYS
0.88
0.25
0.73
10
65
A
GLY
0.92
0.41
0.69
10
66
A
ILE
0.70
0.64
0.55
10
67
A
SER
0.85
0.36
0.55
10
68
A
GLU
0.81
0.33
0.54
10
69
A
ALA
0.53
0.38
0.54
9
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.47
4
77
A
GLU
0.74
0.33
0.50
8
79
A
ALA
0.58
0.38
0.49
6
80
A
LYS
0.73
0.25
0.65
7
81
A
LEU
0.49
0.70
0.64
10
82
A
VAL
0.57
0.56
0.55
10
83
A
PRO
0.52
0.47
0.68
5
16
A
GLU
0.10
0.33
0.73
10
18
A
GLU
0.17
0.33
0.56
3
22
A
PRO
0.57
0.47
0.53
10
24
A
PRO
0.47
0.47
0.41
10
26
A
SER
0.58
0.36
0.46
10
27
A
ARG
0.43
0.51
0.64
10
28
A
LEU
0.86
0.70
0.37
10
30
A
GLN
0.50
0.43
0.54
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.40
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.52
10
37
A
ASP
0.93
0.32
0.50
10
38
A
VAL
0.66
0.56
0.63
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.58
10
44
A
ALA
0.54
0.38
0.61
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.38
10
47
A
HIS
0.47
0.60
0.43
10
48
A
THR
0.87
0.33
0.42
10
49
A
VAL
0.56
0.56
0.48
10
50
A
GLU
0.77
0.33
0.47
10
52
A
VAL
0.62
0.56
0.47
10
53
A
ALA
0.81
0.38
0.61
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.54
10
56
A
PRO
0.77
0.47
0.58
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.61
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.50
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.66
10
66
A
ILE
0.70
0.64
0.48
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.51
10
70
A
LYS
0.93
0.25
0.37
10
73
A
LYS
0.88
0.25
0.44
10
75
A
LEU
0.65
0.70
0.24
10
76
A
ALA
0.49
0.38
0.44
6
77
A
GLU
0.74
0.33
0.46
10
79
A
ALA
0.58
0.38
0.47
9
80
A
LYS
0.73
0.25
0.66
7
81
A
LEU
0.49
0.70
0.60
10
82
A
VAL
0.57
0.56
0.53
10
83
A
PRO
0.52
0.47
0.64
3
18
A
GLU
0.17
0.33
0.47
10
20
A
PHE
0.22
1.00
0.64
9
22
A
PRO
0.57
0.47
0.57
1
24
A
PRO
0.47
0.47
0.46
10
26
A
SER
0.58
0.36
0.48
10
27
A
ARG
0.43
0.51
0.64
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.62
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.50
10
37
A
ASP
0.93
0.32
0.45
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.63
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.50
10
46
A
PHE
0.57
1.00
0.30
10
47
A
HIS
0.47
0.60
0.49
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.45
10
52
A
VAL
0.62
0.56
0.43
10
53
A
ALA
0.81
0.38
0.57
10
54
A
TYR
0.64
0.80
0.68
10
55
A
ALA
0.67
0.38
0.59
10
56
A
PRO
0.77
0.47
0.62
10
57
A
LYS
0.67
0.25
0.45
1
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.62
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.54
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.53
10
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.42
8
77
A
GLU
0.74
0.33
0.44
10
79
A
ALA
0.58
0.38
0.45
9
80
A
LYS
0.73
0.25
0.61
10
81
A
LEU
0.49
0.70
0.56
10
82
A
VAL
0.57
0.56
0.55
10
83
A
PRO
0.52
0.47
0.62
9
16
A
GLU
0.10
0.33
0.62
4
17
A
GLU
0.15
0.33
0.57
6
19
A
SER
0.16
0.36
0.54
2
21
A
GLY
0.47
0.41
0.56
2
23
A
GLN
0.41
0.43
0.49
10
24
A
PRO
0.47
0.47
0.51
10
26
A
SER
0.58
0.36
0.46
9
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.38
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.64
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.42
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.52
10
37
A
ASP
0.93
0.32
0.45
10
38
A
VAL
0.66
0.56
0.59
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.62
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.50
10
46
A
PHE
0.57
1.00
0.29
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.50
10
49
A
VAL
0.56
0.56
0.45
10
50
A
GLU
0.77
0.33
0.44
10
52
A
VAL
0.62
0.56
0.26
6
53
A
ALA
0.81
0.38
0.51
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.58
10
58
A
LYS
0.59
0.25
0.62
10
59
A
GLU
0.50
0.33
0.60
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.56
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.52
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.53
8
73
A
LYS
0.88
0.25
0.48
10
76
A
ALA
0.49
0.38
0.43
1
77
A
GLU
0.74
0.33
0.48
7
79
A
ALA
0.58
0.38
0.44
4
80
A
LYS
0.73
0.25
0.65
7
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.52
10
83
A
PRO
0.52
0.47
0.63
4
84
A
MET
0.44
0.66
0.70
2
85
A
GLY
0.62
0.41
0.80
2
16
A
GLU
0.10
0.33
0.68
10
24
A
PRO
0.47
0.47
0.46
10
26
A
SER
0.58
0.36
0.49
10
27
A
ARG
0.43
0.51
0.64
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.37
10
34
A
ASN
0.61
0.39
0.50
10
35
A
ALA
0.53
0.38
0.49
10
37
A
ASP
0.93
0.32
0.43
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.43
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.62
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.30
10
47
A
HIS
0.47
0.60
0.48
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.51
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.43
10
53
A
ALA
0.81
0.38
0.61
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.54
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.61
10
59
A
GLU
0.50
0.33
0.61
10
60
A
LEU
0.91
0.70
0.28
10
62
A
ASN
0.47
0.39
0.62
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.54
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.53
10
73
A
LYS
0.88
0.25
0.47
10
75
A
LEU
0.65
0.70
0.23
9
77
A
GLU
0.74
0.33
0.46
5
79
A
ALA
0.58
0.38
0.48
6
80
A
LYS
0.73
0.25
0.67
4
81
A
LEU
0.49
0.70
0.62
10
82
A
VAL
0.57
0.56
0.51
10
83
A
PRO
0.52
0.47
0.62
4
18
A
GLU
0.17
0.33
0.54
10
20
A
PHE
0.22
1.00
0.64
1
21
A
GLY
0.47
0.41
0.62
1
22
A
PRO
0.57
0.47
0.62
10
24
A
PRO
0.47
0.47
0.52
10
26
A
SER
0.58
0.36
0.52
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.57
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.41
10
34
A
ASN
0.61
0.39
0.55
10
35
A
ALA
0.53
0.38
0.54
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.63
10
39
A
LYS
0.61
0.25
0.57
10
41
A
LEU
0.88
0.70
0.49
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.53
10
44
A
ALA
0.54
0.38
0.61
10
45
A
GLY
0.95
0.41
0.54
10
46
A
PHE
0.57
1.00
0.37
10
47
A
HIS
0.47
0.60
0.46
10
48
A
THR
0.87
0.33
0.45
10
49
A
VAL
0.56
0.56
0.54
10
50
A
GLU
0.77
0.33
0.45
9
52
A
VAL
0.62
0.56
0.50
10
53
A
ALA
0.81
0.38
0.66
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.56
10
56
A
PRO
0.77
0.47
0.60
10
58
A
LYS
0.59
0.25
0.66
10
59
A
GLU
0.50
0.33
0.62
10
60
A
LEU
0.91
0.70
0.32
10
62
A
ASN
0.47
0.39
0.67
10
63
A
ILE
0.61
0.64
0.60
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.69
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.56
10
68
A
GLU
0.81
0.33
0.57
10
69
A
ALA
0.53
0.38
0.54
10
73
A
LYS
0.88
0.25
0.46
10
77
A
GLU
0.74
0.33
0.47
10
79
A
ALA
0.58
0.38
0.51
7
80
A
LYS
0.73
0.25
0.66
4
81
A
LEU
0.49
0.70
0.56
10
82
A
VAL
0.57
0.56
0.51
7
83
A
PRO
0.52
0.47
0.68
3
84
A
MET
0.44
0.66
0.76
6
85
A
GLY
0.62
0.41
0.74
1
17
A
GLU
0.15
0.33
0.57
7
19
A
SER
0.16
0.36
0.56
2
24
A
PRO
0.47
0.47
0.44
9
26
A
SER
0.58
0.36
0.47
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.42
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.51
10
37
A
ASP
0.93
0.32
0.47
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.44
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.59
10
44
A
ALA
0.54
0.38
0.58
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.32
10
47
A
HIS
0.47
0.60
0.46
10
48
A
THR
0.87
0.33
0.42
10
49
A
VAL
0.56
0.56
0.48
10
50
A
GLU
0.77
0.33
0.45
10
52
A
VAL
0.62
0.56
0.43
10
53
A
ALA
0.81
0.38
0.58
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.55
10
56
A
PRO
0.77
0.47
0.60
10
58
A
LYS
0.59
0.25
0.59
10
59
A
GLU
0.50
0.33
0.62
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.53
10
73
A
LYS
0.88
0.25
0.47
10
76
A
ALA
0.49
0.38
0.43
5
77
A
GLU
0.74
0.33
0.40
7
79
A
ALA
0.58
0.38
0.43
4
80
A
LYS
0.73
0.25
0.63
5
81
A
LEU
0.49
0.70
0.56
10
82
A
VAL
0.57
0.56
0.51
10
83
A
PRO
0.52
0.47
0.61
2
16
A
GLU
0.10
0.33
0.73
10
17
A
GLU
0.15
0.33
0.57
10
20
A
PHE
0.22
1.00
0.61
5
21
A
GLY
0.47
0.41
0.58
9
22
A
PRO
0.57
0.47
0.57
10
24
A
PRO
0.47
0.47
0.47
10
26
A
SER
0.58
0.36
0.50
10
27
A
ARG
0.43
0.51
0.62
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.40
10
34
A
ASN
0.61
0.39
0.49
10
35
A
ALA
0.53
0.38
0.50
10
37
A
ASP
0.93
0.32
0.44
10
38
A
VAL
0.66
0.56
0.59
10
39
A
LYS
0.61
0.25
0.51
10
41
A
LEU
0.88
0.70
0.44
10
42
A
GLU
0.58
0.33
0.62
10
43
A
GLU
0.59
0.33
0.62
10
44
A
ALA
0.54
0.38
0.54
10
45
A
GLY
0.95
0.41
0.49
10
46
A
PHE
0.57
1.00
0.29
10
47
A
HIS
0.47
0.60
0.49
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.51
10
50
A
GLU
0.77
0.33
0.45
10
52
A
VAL
0.62
0.56
0.41
10
53
A
ALA
0.81
0.38
0.57
10
54
A
TYR
0.64
0.80
0.64
10
55
A
ALA
0.67
0.38
0.55
10
56
A
PRO
0.77
0.47
0.60
10
58
A
LYS
0.59
0.25
0.62
10
59
A
GLU
0.50
0.33
0.60
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.53
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.51
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.54
10
69
A
ALA
0.53
0.38
0.53
10
72
A
ASP
0.55
0.32
0.38
10
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.45
10
77
A
GLU
0.74
0.33
0.44
10
79
A
ALA
0.58
0.38
0.47
10
80
A
LYS
0.73
0.25
0.63
10
81
A
LEU
0.49
0.70
0.59
10
82
A
VAL
0.57
0.56
0.52
10
83
A
PRO
0.52
0.47
0.67
10
84
A
MET
0.44
0.66
0.73
5
85
A
GLY
0.62
0.41
0.74
5
17
A
GLU
0.15
0.33
0.52
8
20
A
PHE
0.22
1.00
0.56
7
22
A
PRO
0.57
0.47
0.56
1
24
A
PRO
0.47
0.47
0.43
10
26
A
SER
0.58
0.36
0.44
10
27
A
ARG
0.43
0.51
0.61
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.53
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.57
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.49
10
37
A
ASP
0.93
0.32
0.44
10
38
A
VAL
0.66
0.56
0.59
10
39
A
LYS
0.61
0.25
0.51
10
41
A
LEU
0.88
0.70
0.41
10
42
A
GLU
0.58
0.33
0.62
10
43
A
GLU
0.59
0.33
0.62
10
44
A
ALA
0.54
0.38
0.56
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.31
10
47
A
HIS
0.47
0.60
0.45
10
48
A
THR
0.87
0.33
0.43
10
49
A
VAL
0.56
0.56
0.50
10
50
A
GLU
0.77
0.33
0.47
10
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.61
10
54
A
TYR
0.64
0.80
0.64
10
55
A
ALA
0.67
0.38
0.50
10
56
A
PRO
0.77
0.47
0.55
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.58
10
60
A
LEU
0.91
0.70
0.24
10
62
A
ASN
0.47
0.39
0.61
10
63
A
ILE
0.61
0.64
0.50
10
64
A
LYS
0.88
0.25
0.68
10
65
A
GLY
0.92
0.41
0.65
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.53
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.41
10
73
A
LYS
0.88
0.25
0.45
10
75
A
LEU
0.65
0.70
0.22
10
77
A
GLU
0.74
0.33
0.47
10
79
A
ALA
0.58
0.38
0.47
9
80
A
LYS
0.73
0.25
0.66
8
81
A
LEU
0.49
0.70
0.56
10
82
A
VAL
0.57
0.56
0.51
9
83
A
PRO
0.52
0.47
0.66
3
84
A
MET
0.44
0.66
0.75
1
85
A
GLY
0.62
0.41
0.76
1
16
A
GLU
0.10
0.33
0.69
10
17
A
GLU
0.15
0.33
0.64
5
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.50
10
27
A
ARG
0.43
0.51
0.66
10
28
A
LEU
0.86
0.70
0.41
10
30
A
GLN
0.50
0.43
0.59
10
31
A
CYS
0.59
0.64
0.65
10
32
A
GLY
0.94
0.41
0.62
10
33
A
ILE
0.76
0.64
0.45
10
34
A
ASN
0.61
0.39
0.57
10
35
A
ALA
0.53
0.38
0.56
10
37
A
ASP
0.93
0.32
0.51
10
38
A
VAL
0.66
0.56
0.63
10
39
A
LYS
0.61
0.25
0.54
5
41
A
LEU
0.88
0.70
0.50
10
42
A
GLU
0.58
0.33
0.65
10
43
A
GLU
0.59
0.33
0.49
7
44
A
ALA
0.54
0.38
0.60
10
45
A
GLY
0.95
0.41
0.55
10
46
A
PHE
0.57
1.00
0.38
10
47
A
HIS
0.47
0.60
0.51
10
48
A
THR
0.87
0.33
0.46
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.43
10
53
A
ALA
0.81
0.38
0.57
10
54
A
TYR
0.64
0.80
0.71
10
55
A
ALA
0.67
0.38
0.61
10
56
A
PRO
0.77
0.47
0.61
10
58
A
LYS
0.59
0.25
0.64
10
59
A
GLU
0.50
0.33
0.64
10
62
A
ASN
0.47
0.39
0.67
10
63
A
ILE
0.61
0.64
0.62
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.69
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.55
10
68
A
GLU
0.81
0.33
0.58
10
69
A
ALA
0.53
0.38
0.54
10
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.47
1
77
A
GLU
0.74
0.33
0.49
8
79
A
ALA
0.58
0.38
0.49
3
80
A
LYS
0.73
0.25
0.67
8
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.52
10
83
A
PRO
0.52
0.47
0.64
7
16
A
GLU
0.10
0.33
0.73
10
17
A
GLU
0.15
0.33
0.56
4
24
A
PRO
0.47
0.47
0.49
10
26
A
SER
0.58
0.36
0.50
10
27
A
ARG
0.43
0.51
0.64
10
30
A
GLN
0.50
0.43
0.54
10
31
A
CYS
0.59
0.64
0.61
10
32
A
GLY
0.94
0.41
0.57
10
33
A
ILE
0.76
0.64
0.38
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.49
10
37
A
ASP
0.93
0.32
0.46
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.51
9
41
A
LEU
0.88
0.70
0.44
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.63
10
44
A
ALA
0.54
0.38
0.57
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.32
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.50
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.63
10
54
A
TYR
0.64
0.80
0.63
10
55
A
ALA
0.67
0.38
0.49
10
56
A
PRO
0.77
0.47
0.57
10
58
A
LYS
0.59
0.25
0.61
9
59
A
GLU
0.50
0.33
0.61
10
60
A
LEU
0.91
0.70
0.28
10
61
A
ILE
0.35
0.64
0.39
10
62
A
ASN
0.47
0.39
0.64
10
63
A
ILE
0.61
0.64
0.54
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.51
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.52
10
73
A
LYS
0.88
0.25
0.45
9
76
A
ALA
0.49
0.38
0.44
9
77
A
GLU
0.74
0.33
0.46
7
79
A
ALA
0.58
0.38
0.49
3
80
A
LYS
0.73
0.25
0.65
3
81
A
LEU
0.49
0.70
0.60
10
82
A
VAL
0.57
0.56
0.54
6
17
A
GLU
0.15
0.33
0.65
10
23
A
GLN
0.41
0.43
0.38
7
24
A
PRO
0.47
0.47
0.47
10
26
A
SER
0.58
0.36
0.49
10
27
A
ARG
0.43
0.51
0.64
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.41
10
34
A
ASN
0.61
0.39
0.45
10
35
A
ALA
0.53
0.38
0.52
10
37
A
ASP
0.93
0.32
0.47
10
38
A
VAL
0.66
0.56
0.62
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.44
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.64
10
44
A
ALA
0.54
0.38
0.59
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.42
10
48
A
THR
0.87
0.33
0.48
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.44
10
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.63
10
54
A
TYR
0.64
0.80
0.65
10
55
A
ALA
0.67
0.38
0.58
10
56
A
PRO
0.77
0.47
0.61
10
58
A
LYS
0.59
0.25
0.65
10
59
A
GLU
0.50
0.33
0.63
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.52
10
69
A
ALA
0.53
0.38
0.54
10
70
A
LYS
0.93
0.25
0.46
10
73
A
LYS
0.88
0.25
0.49
10
76
A
ALA
0.49
0.38
0.47
6
77
A
GLU
0.74
0.33
0.48
9
79
A
ALA
0.58
0.38
0.51
7
80
A
LYS
0.73
0.25
0.68
7
81
A
LEU
0.49
0.70
0.59
10
82
A
VAL
0.57
0.56
0.50
7
83
A
PRO
0.52
0.47
0.64
7
16
A
GLU
0.10
0.33
0.64
10
17
A
GLU
0.15
0.33
0.67
10
18
A
GLU
0.17
0.33
0.59
10
19
A
SER
0.16
0.36
0.43
3
22
A
PRO
0.57
0.47
0.55
3
23
A
GLN
0.41
0.43
0.39
9
24
A
PRO
0.47
0.47
0.44
10
26
A
SER
0.58
0.36
0.47
10
27
A
ARG
0.43
0.51
0.61
10
28
A
LEU
0.86
0.70
0.35
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.42
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.51
10
37
A
ASP
0.93
0.32
0.50
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.47
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.61
10
44
A
ALA
0.54
0.38
0.57
10
45
A
GLY
0.95
0.41
0.50
10
46
A
PHE
0.57
1.00
0.32
10
47
A
HIS
0.47
0.60
0.44
10
48
A
THR
0.87
0.33
0.44
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.48
10
52
A
VAL
0.62
0.56
0.49
10
53
A
ALA
0.81
0.38
0.55
10
54
A
TYR
0.64
0.80
0.68
10
56
A
PRO
0.77
0.47
0.54
10
58
A
LYS
0.59
0.25
0.58
10
59
A
GLU
0.50
0.33
0.58
10
62
A
ASN
0.47
0.39
0.62
10
63
A
ILE
0.61
0.64
0.54
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.65
10
66
A
ILE
0.70
0.64
0.49
10
67
A
SER
0.85
0.36
0.50
10
68
A
GLU
0.81
0.33
0.51
10
69
A
ALA
0.53
0.38
0.50
10
70
A
LYS
0.93
0.25
0.40
10
73
A
LYS
0.88
0.25
0.45
10
75
A
LEU
0.65
0.70
0.25
10
76
A
ALA
0.49
0.38
0.44
9
77
A
GLU
0.74
0.33
0.49
10
79
A
ALA
0.58
0.38
0.51
10
80
A
LYS
0.73
0.25
0.65
10
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.53
10
83
A
PRO
0.52
0.47
0.65
10
84
A
MET
0.44
0.66
0.74
3
85
A
GLY
0.62
0.41
0.68
3
17
A
GLU
0.15
0.33
0.65
10
18
A
GLU
0.17
0.33
0.59
1
22
A
PRO
0.57
0.47
0.56
10
24
A
PRO
0.47
0.47
0.50
10
26
A
SER
0.58
0.36
0.53
10
27
A
ARG
0.43
0.51
0.67
10
28
A
LEU
0.86
0.70
0.40
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.64
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.43
10
34
A
ASN
0.61
0.39
0.54
10
35
A
ALA
0.53
0.38
0.50
10
37
A
ASP
0.93
0.32
0.46
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.53
9
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.57
10
44
A
ALA
0.54
0.38
0.58
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.36
10
47
A
HIS
0.47
0.60
0.47
10
48
A
THR
0.87
0.33
0.47
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.48
10
52
A
VAL
0.62
0.56
0.37
10
53
A
ALA
0.81
0.38
0.56
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.62
10
59
A
GLU
0.50
0.33
0.62
10
60
A
LEU
0.91
0.70
0.32
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.59
10
64
A
LYS
0.88
0.25
0.69
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.51
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.51
10
69
A
ALA
0.53
0.38
0.51
8
70
A
LYS
0.93
0.25
0.41
10
73
A
LYS
0.88
0.25
0.46
10
76
A
ALA
0.49
0.38
0.40
5
77
A
GLU
0.74
0.33
0.47
10
79
A
ALA
0.58
0.38
0.48
9
80
A
LYS
0.73
0.25
0.62
9
81
A
LEU
0.49
0.70
0.60
10
82
A
VAL
0.57
0.56
0.55
10
83
A
PRO
0.52
0.47
0.62
1
16
A
GLU
0.10
0.33
0.69
10
18
A
GLU
0.17
0.33
0.58
4
24
A
PRO
0.47
0.47
0.44
10
26
A
SER
0.58
0.36
0.46
10
27
A
ARG
0.43
0.51
0.65
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.53
10
31
A
CYS
0.59
0.64
0.62
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.40
10
34
A
ASN
0.61
0.39
0.44
10
35
A
ALA
0.53
0.38
0.51
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.61
10
39
A
LYS
0.61
0.25
0.51
10
41
A
LEU
0.88
0.70
0.46
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.48
10
44
A
ALA
0.54
0.38
0.60
10
45
A
GLY
0.95
0.41
0.51
10
46
A
PHE
0.57
1.00
0.34
10
47
A
HIS
0.47
0.60
0.42
10
48
A
THR
0.87
0.33
0.40
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.64
10
54
A
TYR
0.64
0.80
0.66
10
55
A
ALA
0.67
0.38
0.54
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.61
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.57
10
64
A
LYS
0.88
0.25
0.66
10
65
A
GLY
0.92
0.41
0.67
10
66
A
ILE
0.70
0.64
0.50
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.51
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.44
10
73
A
LYS
0.88
0.25
0.47
10
76
A
ALA
0.49
0.38
0.44
6
77
A
GLU
0.74
0.33
0.46
9
79
A
ALA
0.58
0.38
0.47
8
80
A
LYS
0.73
0.25
0.65
8
81
A
LEU
0.49
0.70
0.60
10
82
A
VAL
0.57
0.56
0.49
10
83
A
PRO
0.52
0.47
0.61
4
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.52
10
27
A
ARG
0.43
0.51
0.62
10
28
A
LEU
0.86
0.70
0.36
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.64
10
32
A
GLY
0.94
0.41
0.59
10
33
A
ILE
0.76
0.64
0.42
10
34
A
ASN
0.61
0.39
0.47
10
35
A
ALA
0.53
0.38
0.52
10
37
A
ASP
0.93
0.32
0.48
10
38
A
VAL
0.66
0.56
0.62
10
39
A
LYS
0.61
0.25
0.53
10
41
A
LEU
0.88
0.70
0.45
10
42
A
GLU
0.58
0.33
0.63
10
43
A
GLU
0.59
0.33
0.58
10
44
A
ALA
0.54
0.38
0.59
10
45
A
GLY
0.95
0.41
0.53
10
46
A
PHE
0.57
1.00
0.35
10
47
A
HIS
0.47
0.60
0.46
10
48
A
THR
0.87
0.33
0.52
10
49
A
VAL
0.56
0.56
0.52
10
50
A
GLU
0.77
0.33
0.45
10
52
A
VAL
0.62
0.56
0.41
10
53
A
ALA
0.81
0.38
0.57
10
54
A
TYR
0.64
0.80
0.67
10
55
A
ALA
0.67
0.38
0.55
10
56
A
PRO
0.77
0.47
0.59
10
58
A
LYS
0.59
0.25
0.62
10
59
A
GLU
0.50
0.33
0.61
10
62
A
ASN
0.47
0.39
0.65
10
63
A
ILE
0.61
0.64
0.53
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.48
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.41
10
73
A
LYS
0.88
0.25
0.47
10
75
A
LEU
0.65
0.70
0.27
10
76
A
ALA
0.49
0.38
0.46
10
77
A
GLU
0.74
0.33
0.48
10
81
A
LEU
0.49
0.70
0.64
9
82
A
VAL
0.57
0.56
0.50
9
17
A
GLU
0.15
0.33
0.54
2
23
A
GLN
0.41
0.43
0.32
1
24
A
PRO
0.47
0.47
0.43
10
26
A
SER
0.58
0.36
0.44
9
27
A
ARG
0.43
0.51
0.62
10
28
A
LEU
0.86
0.70
0.39
10
30
A
GLN
0.50
0.43
0.55
10
31
A
CYS
0.59
0.64
0.62
10
32
A
GLY
0.94
0.41
0.58
10
33
A
ILE
0.76
0.64
0.41
10
34
A
ASN
0.61
0.39
0.52
10
35
A
ALA
0.53
0.38
0.49
10
37
A
ASP
0.93
0.32
0.44
10
38
A
VAL
0.66
0.56
0.60
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.44
10
42
A
GLU
0.58
0.33
0.61
10
43
A
GLU
0.59
0.33
0.61
10
44
A
ALA
0.54
0.38
0.54
10
45
A
GLY
0.95
0.41
0.48
10
47
A
HIS
0.47
0.60
0.45
10
48
A
THR
0.87
0.33
0.42
10
49
A
VAL
0.56
0.56
0.49
10
50
A
GLU
0.77
0.33
0.49
10
52
A
VAL
0.62
0.56
0.48
10
53
A
ALA
0.81
0.38
0.63
10
54
A
TYR
0.64
0.80
0.61
10
55
A
ALA
0.67
0.38
0.53
10
56
A
PRO
0.77
0.47
0.58
10
58
A
LYS
0.59
0.25
0.63
10
59
A
GLU
0.50
0.33
0.60
10
62
A
ASN
0.47
0.39
0.62
10
63
A
ILE
0.61
0.64
0.52
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.65
10
66
A
ILE
0.70
0.64
0.48
10
67
A
SER
0.85
0.36
0.52
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.52
10
70
A
LYS
0.93
0.25
0.42
10
73
A
LYS
0.88
0.25
0.46
10
75
A
LEU
0.65
0.70
0.24
10
76
A
ALA
0.49
0.38
0.46
6
77
A
GLU
0.74
0.33
0.46
9
79
A
ALA
0.58
0.38
0.49
7
80
A
LYS
0.73
0.25
0.65
9
81
A
LEU
0.49
0.70
0.62
10
82
A
VAL
0.57
0.56
0.51
10
83
A
PRO
0.52
0.47
0.64
2
18
A
GLU
0.17
0.33
0.51
7
24
A
PRO
0.47
0.47
0.48
10
26
A
SER
0.58
0.36
0.46
10
27
A
ARG
0.43
0.51
0.63
10
28
A
LEU
0.86
0.70
0.38
10
30
A
GLN
0.50
0.43
0.56
10
31
A
CYS
0.59
0.64
0.63
10
32
A
GLY
0.94
0.41
0.60
10
33
A
ILE
0.76
0.64
0.40
10
34
A
ASN
0.61
0.39
0.53
10
35
A
ALA
0.53
0.38
0.53
10
37
A
ASP
0.93
0.32
0.50
10
38
A
VAL
0.66
0.56
0.63
10
39
A
LYS
0.61
0.25
0.54
10
41
A
LEU
0.88
0.70
0.47
10
42
A
GLU
0.58
0.33
0.64
10
43
A
GLU
0.59
0.33
0.54
10
44
A
ALA
0.54
0.38
0.60
10
45
A
GLY
0.95
0.41
0.52
10
46
A
PHE
0.57
1.00
0.35
10
47
A
HIS
0.47
0.60
0.44
10
48
A
THR
0.87
0.33
0.43
10
49
A
VAL
0.56
0.56
0.50
10
50
A
GLU
0.77
0.33
0.46
10
52
A
VAL
0.62
0.56
0.46
10
53
A
ALA
0.81
0.38
0.58
10
54
A
TYR
0.64
0.80
0.65
10
55
A
ALA
0.67
0.38
0.52
10
56
A
PRO
0.77
0.47
0.57
10
58
A
LYS
0.59
0.25
0.60
10
59
A
GLU
0.50
0.33
0.61
10
60
A
LEU
0.91
0.70
0.30
10
62
A
ASN
0.47
0.39
0.66
10
63
A
ILE
0.61
0.64
0.57
10
64
A
LYS
0.88
0.25
0.70
10
65
A
GLY
0.92
0.41
0.68
10
66
A
ILE
0.70
0.64
0.53
10
67
A
SER
0.85
0.36
0.54
10
68
A
GLU
0.81
0.33
0.53
10
69
A
ALA
0.53
0.38
0.54
10
73
A
LYS
0.88
0.25
0.47
10
76
A
ALA
0.49
0.38
0.44
9
77
A
GLU
0.74
0.33
0.45
10
79
A
ALA
0.58
0.38
0.47
10
80
A
LYS
0.73
0.25
0.63
10
81
A
LEU
0.49
0.70
0.61
10
82
A
VAL
0.57
0.56
0.48
10
83
A
PRO
0.52
0.47
0.65
8