Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1BBO chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
4
A
CYS
1.00
0.64
0.39
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
8
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.28
9
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.40
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.66
8
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.04
2
24
A
HIS
1.00
0.60
0.31
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.58
6
43
A
GLY
0.70
0.41
0.48
6
45
A
LEU
0.94
0.70
0.22
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
1
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
6
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.48
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.66
6
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.43
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.38
10
25
A
THR
0.86
0.33
0.53
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.43
4
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
3
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.36
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.66
6
14
A
PRO
0.68
0.47
0.57
10
15
A
SER
0.74
0.36
0.57
4
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.04
10
21
A
ILE
0.73
0.64
0.30
9
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.50
9
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.18
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
38
A
SER
0.68
0.36
0.19
1
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
4
43
A
GLY
0.70
0.41
0.44
3
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
8
51
A
SER
0.70
0.36
0.53
1
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
5
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
1
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
1
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.67
7
13
A
LYS
0.53
0.25
0.65
6
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.55
3
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.52
3
19
A
LYS
0.38
0.25
0.40
3
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.36
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.54
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.46
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
7
33
A
THR
0.41
0.33
0.54
7
34
A
TYR
0.70
0.80
0.55
7
35
A
CYS
1.00
0.64
0.49
7
36
A
ASN
0.80
0.39
0.61
7
37
A
PHE
0.80
1.00
0.34
7
38
A
SER
0.68
0.36
0.23
7
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.24
2
42
A
LYS
0.66
0.25
0.56
6
45
A
LEU
0.94
0.70
0.20
7
48
A
HIS
1.00
0.60
0.23
7
49
A
MET
0.69
0.66
0.30
7
52
A
LYS
0.95
0.25
0.72
7
53
A
ALA
0.83
0.38
0.53
5
54
A
HIS
0.89
0.60
0.50
7
55
A
SER
0.86
0.36
0.50
5
57
A
LYS
0.04
0.25
0.77
7
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.25
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.37
10
22
A
ARG
0.86
0.51
0.50
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.50
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
3
43
A
GLY
0.70
0.41
0.44
8
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.30
9
52
A
LYS
0.95
0.25
0.73
6
53
A
ALA
0.83
0.38
0.58
6
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
1
56
A
LYS
0.82
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.56
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.65
5
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.56
1
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.05
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.35
10
25
A
THR
0.86
0.33
0.52
9
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.45
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.41
2
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.28
4
52
A
LYS
0.95
0.25
0.73
9
53
A
ALA
0.83
0.38
0.58
7
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.48
1
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.36
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.67
9
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
3
16
A
MET
0.41
0.66
0.51
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.30
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.07
1
24
A
HIS
1.00
0.60
0.23
10
25
A
THR
0.86
0.33
0.46
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.57
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.61
6
43
A
GLY
0.70
0.41
0.50
10
45
A
LEU
0.94
0.70
0.24
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.31
10
51
A
SER
0.70
0.36
0.51
1
52
A
LYS
0.95
0.25
0.67
4
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
1
56
A
LYS
0.82
0.25
0.66
1
57
A
LYS
0.04
0.25
0.80
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.35
10
8
A
GLY
0.84
0.41
0.48
10
9
A
ILE
0.76
0.64
0.26
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
8
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.59
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.24
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.35
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.10
1
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.52
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.48
10
28
A
ARG
0.79
0.51
0.29
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
2
43
A
GLY
0.70
0.41
0.46
7
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.53
1
52
A
LYS
0.95
0.25
0.72
9
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
7
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
1
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.38
10
8
A
GLY
0.84
0.41
0.51
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
6
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
7
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.52
3
19
A
LYS
0.38
0.25
0.45
3
20
A
HIS
1.00
0.60
0.05
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.28
10
25
A
THR
0.86
0.33
0.48
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.19
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.30
7
33
A
THR
0.41
0.33
0.56
7
34
A
TYR
0.70
0.80
0.55
7
35
A
CYS
1.00
0.64
0.49
7
36
A
ASN
0.80
0.39
0.63
7
37
A
PHE
0.80
1.00
0.32
8
38
A
SER
0.68
0.36
0.21
6
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.25
3
41
A
THR
0.59
0.33
0.31
1
42
A
LYS
0.66
0.25
0.60
7
43
A
GLY
0.70
0.41
0.47
7
45
A
LEU
0.94
0.70
0.23
7
48
A
HIS
1.00
0.60
0.20
7
49
A
MET
0.69
0.66
0.30
7
52
A
LYS
0.95
0.25
0.69
1
53
A
ALA
0.83
0.38
0.53
7
54
A
HIS
0.89
0.60
0.49
7
55
A
SER
0.86
0.36
0.51
1
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.79
7
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.52
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.65
5
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.34
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.56
10
27
A
VAL
0.91
0.56
0.41
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.43
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
2
43
A
GLY
0.70
0.41
0.44
4
45
A
LEU
0.94
0.70
0.17
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.55
3
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.47
1
56
A
LYS
0.82
0.25
0.71
7
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.66
9
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.57
5
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.03
3
24
A
HIS
1.00
0.60
0.34
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.29
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.55
3
43
A
GLY
0.70
0.41
0.43
1
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.54
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.70
6
13
A
LYS
0.53
0.25
0.65
9
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.54
1
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.28
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.34
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.21
2
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
3
43
A
GLY
0.70
0.41
0.43
6
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
9
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.50
3
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.03
1
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
5
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.58
10
37
A
PHE
0.80
1.00
0.28
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.58
2
43
A
GLY
0.70
0.41
0.49
9
45
A
LEU
0.94
0.70
0.23
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.73
3
53
A
ALA
0.83
0.38
0.54
7
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.62
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
8
13
A
LYS
0.53
0.25
0.64
3
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.41
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.45
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
9
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.37
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.50
2
43
A
GLY
0.70
0.41
0.40
4
45
A
LEU
0.94
0.70
0.16
10
48
A
HIS
1.00
0.60
0.24
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.70
8
53
A
ALA
0.83
0.38
0.51
10
54
A
HIS
0.89
0.60
0.49
10
55
A
SER
0.86
0.36
0.47
4
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.48
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
8
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.56
3
16
A
MET
0.41
0.66
0.39
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.53
1
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.38
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.09
6
24
A
HIS
1.00
0.60
0.40
10
25
A
THR
0.86
0.33
0.54
10
26
A
ASP
0.94
0.32
0.60
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.24
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.37
9
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.27
9
33
A
THR
0.41
0.33
0.53
9
34
A
TYR
0.70
0.80
0.53
9
35
A
CYS
1.00
0.64
0.48
9
36
A
ASN
0.80
0.39
0.60
9
37
A
PHE
0.80
1.00
0.33
9
38
A
SER
0.68
0.36
0.19
9
39
A
PHE
0.97
1.00
0.00
9
42
A
LYS
0.66
0.25
0.52
4
43
A
GLY
0.70
0.41
0.40
8
45
A
LEU
0.94
0.70
0.21
9
48
A
HIS
1.00
0.60
0.22
9
49
A
MET
0.69
0.66
0.30
9
50
A
LYS
0.76
0.25
0.62
2
51
A
SER
0.70
0.36
0.49
2
52
A
LYS
0.95
0.25
0.71
6
53
A
ALA
0.83
0.38
0.53
9
54
A
HIS
0.89
0.60
0.47
9
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.74
9
57
A
LYS
0.04
0.25
0.74
9
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.69
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.59
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.68
5
13
A
LYS
0.53
0.25
0.65
5
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.24
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.52
1
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
6
43
A
GLY
0.70
0.41
0.44
9
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.32
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.60
7
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.58
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.52
10
7
A
CYS
1.00
0.64
0.43
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
1
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
8
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.48
9
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.22
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.53
3
43
A
GLY
0.70
0.41
0.44
10
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.72
4
53
A
ALA
0.83
0.38
0.57
3
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.68
1
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.62
10
6
A
GLU
0.74
0.33
0.48
10
7
A
CYS
1.00
0.64
0.39
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
5
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
5
16
A
MET
0.41
0.66
0.50
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.51
10
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.22
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.32
10
38
A
SER
0.68
0.36
0.23
5
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
5
43
A
GLY
0.70
0.41
0.46
7
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.31
10
51
A
SER
0.70
0.36
0.57
3
52
A
LYS
0.95
0.25
0.72
9
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
3
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.70
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.30
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.52
3
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.17
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.30
9
52
A
LYS
0.95
0.25
0.72
4
53
A
ALA
0.83
0.38
0.58
9
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.76
10
57
A
LYS
0.04
0.25
0.66
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.58
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.57
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
8
13
A
LYS
0.53
0.25
0.64
3
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
1
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.46
10
24
A
HIS
1.00
0.60
0.35
10
25
A
THR
0.86
0.33
0.52
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.31
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.31
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
8
52
A
LYS
0.95
0.25
0.75
9
53
A
ALA
0.83
0.38
0.59
10
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.49
2
56
A
LYS
0.82
0.25
0.77
10
57
A
LYS
0.04
0.25
0.68
6
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.55
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
6
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
4
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.49
10
23
A
THR
0.69
0.33
0.06
1
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.20
8
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
3
43
A
GLY
0.70
0.41
0.47
10
45
A
LEU
0.94
0.70
0.18
10
47
A
LYS
0.36
0.25
0.48
1
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.30
10
50
A
LYS
0.76
0.25
0.63
1
51
A
SER
0.70
0.36
0.57
1
52
A
LYS
0.95
0.25
0.72
7
53
A
ALA
0.83
0.38
0.56
9
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.49
5
56
A
LYS
0.82
0.25
0.65
1
57
A
LYS
0.04
0.25
0.79
2
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.66
10
13
A
LYS
0.53
0.25
0.62
9
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.54
1
16
A
MET
0.41
0.66
0.40
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.47
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
4
43
A
GLY
0.70
0.41
0.44
1
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.24
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.70
9
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.48
10
55
A
SER
0.86
0.36
0.48
6
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.73
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.68
7
14
A
PRO
0.68
0.47
0.61
10
15
A
SER
0.74
0.36
0.59
4
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.08
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.46
10
24
A
HIS
1.00
0.60
0.34
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.50
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.60
10
34
A
TYR
0.70
0.80
0.60
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.36
10
38
A
SER
0.68
0.36
0.21
4
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.44
1
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
3
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
9
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
4
A
CYS
1.00
0.64
0.37
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.54
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.71
9
14
A
PRO
0.68
0.47
0.59
6
16
A
MET
0.41
0.66
0.49
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.02
4
24
A
HIS
1.00
0.60
0.29
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.55
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
1
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.59
1
52
A
LYS
0.95
0.25
0.71
2
53
A
ALA
0.83
0.38
0.49
9
54
A
HIS
0.89
0.60
0.49
10
57
A
LYS
0.04
0.25
0.77
8
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
5
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.35
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.05
1
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.35
10
38
A
SER
0.68
0.36
0.21
1
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
5
43
A
GLY
0.70
0.41
0.42
6
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.26
10
52
A
LYS
0.95
0.25
0.71
9
53
A
ALA
0.83
0.38
0.51
6
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.67
1
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.50
10
7
A
CYS
1.00
0.64
0.37
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.29
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.59
4
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.07
1
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.48
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.13
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.30
10
38
A
SER
0.68
0.36
0.18
7
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.60
9
43
A
GLY
0.70
0.41
0.47
7
45
A
LEU
0.94
0.70
0.22
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.29
10
53
A
ALA
0.83
0.38
0.49
9
54
A
HIS
0.89
0.60
0.48
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
9
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.58
4
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.23
10
18
A
LYS
0.54
0.25
0.51
2
19
A
LYS
0.38
0.25
0.43
2
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.35
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.07
2
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
8
33
A
THR
0.41
0.33
0.55
8
34
A
TYR
0.70
0.80
0.57
8
35
A
CYS
1.00
0.64
0.52
8
36
A
ASN
0.80
0.39
0.61
8
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.22
10
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.20
2
41
A
THR
0.59
0.33
0.27
2
43
A
GLY
0.70
0.41
0.46
6
45
A
LEU
0.94
0.70
0.21
8
48
A
HIS
1.00
0.60
0.25
8
49
A
MET
0.69
0.66
0.33
8
51
A
SER
0.70
0.36
0.59
2
52
A
LYS
0.95
0.25
0.73
5
53
A
ALA
0.83
0.38
0.49
8
54
A
HIS
0.89
0.60
0.51
8
56
A
LYS
0.82
0.25
0.72
7
57
A
LYS
0.04
0.25
0.77
8
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.34
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.41
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.47
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.36
10
38
A
SER
0.68
0.36
0.20
5
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.74
7
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.49
4
56
A
LYS
0.82
0.25
0.71
3
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.37
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.64
4
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.28
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
1
43
A
GLY
0.70
0.41
0.46
5
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
2
53
A
ALA
0.83
0.38
0.56
8
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.52
3
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
6
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.67
8
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.56
5
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.42
8
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.28
9
52
A
LYS
0.95
0.25
0.74
10
53
A
ALA
0.83
0.38
0.56
5
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.40
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.66
8
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.04
2
24
A
HIS
1.00
0.60
0.31
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.58
6
43
A
GLY
0.70
0.41
0.48
6
45
A
LEU
0.94
0.70
0.22
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
1
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
6
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.48
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.66
6
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.43
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.38
10
25
A
THR
0.86
0.33
0.53
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.43
4
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
3
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.36
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.66
6
14
A
PRO
0.68
0.47
0.57
10
15
A
SER
0.74
0.36
0.57
3
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.04
10
21
A
ILE
0.73
0.64
0.30
9
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.50
9
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.18
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
38
A
SER
0.68
0.36
0.19
1
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
4
43
A
GLY
0.70
0.41
0.44
4
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
8
51
A
SER
0.70
0.36
0.53
1
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
5
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
1
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
1
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.67
7
13
A
LYS
0.53
0.25
0.65
6
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.55
3
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.52
3
19
A
LYS
0.38
0.25
0.40
3
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.36
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.54
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.46
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
7
33
A
THR
0.41
0.33
0.54
7
34
A
TYR
0.70
0.80
0.55
7
35
A
CYS
1.00
0.64
0.49
7
36
A
ASN
0.80
0.39
0.61
7
37
A
PHE
0.80
1.00
0.34
7
38
A
SER
0.68
0.36
0.23
7
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.24
2
42
A
LYS
0.66
0.25
0.56
6
45
A
LEU
0.94
0.70
0.20
7
48
A
HIS
1.00
0.60
0.23
7
49
A
MET
0.69
0.66
0.30
7
52
A
LYS
0.95
0.25
0.72
7
53
A
ALA
0.83
0.38
0.53
5
54
A
HIS
0.89
0.60
0.50
7
55
A
SER
0.86
0.36
0.50
5
57
A
LYS
0.04
0.25
0.77
7
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.25
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.37
10
22
A
ARG
0.86
0.51
0.50
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.50
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
3
43
A
GLY
0.70
0.41
0.44
8
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.30
9
52
A
LYS
0.95
0.25
0.73
6
53
A
ALA
0.83
0.38
0.58
6
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
1
56
A
LYS
0.82
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.56
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
4
13
A
LYS
0.53
0.25
0.65
6
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.05
10
21
A
ILE
0.73
0.64
0.33
8
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.35
10
25
A
THR
0.86
0.33
0.52
9
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.31
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.41
1
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.28
5
52
A
LYS
0.95
0.25
0.73
7
53
A
ALA
0.83
0.38
0.58
8
54
A
HIS
0.89
0.60
0.55
10
56
A
LYS
0.82
0.25
0.74
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.36
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.67
9
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
3
16
A
MET
0.41
0.66
0.51
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.30
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.07
1
24
A
HIS
1.00
0.60
0.23
10
25
A
THR
0.86
0.33
0.46
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.57
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.61
6
43
A
GLY
0.70
0.41
0.50
10
45
A
LEU
0.94
0.70
0.24
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.31
10
51
A
SER
0.70
0.36
0.51
1
52
A
LYS
0.95
0.25
0.67
4
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
1
56
A
LYS
0.82
0.25
0.66
1
57
A
LYS
0.04
0.25
0.80
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
7
A
CYS
1.00
0.64
0.35
10
8
A
GLY
0.84
0.41
0.48
10
9
A
ILE
0.76
0.64
0.26
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
8
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.59
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.24
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.35
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.10
1
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.52
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.48
10
28
A
ARG
0.79
0.51
0.29
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
2
43
A
GLY
0.70
0.41
0.46
7
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.53
1
52
A
LYS
0.95
0.25
0.72
9
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
7
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
1
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.38
10
8
A
GLY
0.84
0.41
0.51
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
5
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
8
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.52
4
19
A
LYS
0.38
0.25
0.45
4
20
A
HIS
1.00
0.60
0.05
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.28
10
25
A
THR
0.86
0.33
0.48
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.19
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.30
6
33
A
THR
0.41
0.33
0.56
6
34
A
TYR
0.70
0.80
0.55
6
35
A
CYS
1.00
0.64
0.49
6
36
A
ASN
0.80
0.39
0.63
6
37
A
PHE
0.80
1.00
0.32
7
38
A
SER
0.68
0.36
0.21
7
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.25
4
41
A
THR
0.59
0.33
0.31
1
42
A
LYS
0.66
0.25
0.60
6
43
A
GLY
0.70
0.41
0.47
6
45
A
LEU
0.94
0.70
0.23
6
48
A
HIS
1.00
0.60
0.20
6
49
A
MET
0.69
0.66
0.30
6
52
A
LYS
0.95
0.25
0.69
1
53
A
ALA
0.83
0.38
0.53
6
54
A
HIS
0.89
0.60
0.49
6
55
A
SER
0.86
0.36
0.51
1
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.79
6
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.52
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.65
5
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.34
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.56
10
27
A
VAL
0.91
0.56
0.41
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.43
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
2
43
A
GLY
0.70
0.41
0.44
4
45
A
LEU
0.94
0.70
0.17
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.55
3
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.47
1
56
A
LYS
0.82
0.25
0.71
7
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.66
9
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.57
5
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.03
3
24
A
HIS
1.00
0.60
0.34
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.29
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.55
3
43
A
GLY
0.70
0.41
0.43
1
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.54
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.70
6
13
A
LYS
0.53
0.25
0.65
9
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.54
1
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.28
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.34
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.21
2
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
3
43
A
GLY
0.70
0.41
0.43
6
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
9
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.50
3
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.03
1
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
6
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.58
10
37
A
PHE
0.80
1.00
0.28
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.58
3
43
A
GLY
0.70
0.41
0.49
10
45
A
LEU
0.94
0.70
0.23
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.73
3
53
A
ALA
0.83
0.38
0.54
8
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
9
6
A
GLU
0.74
0.33
0.62
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
9
13
A
LYS
0.53
0.25
0.64
3
14
A
PRO
0.68
0.47
0.57
10
15
A
SER
0.74
0.36
0.53
1
16
A
MET
0.41
0.66
0.41
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.45
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
9
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.37
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.50
2
43
A
GLY
0.70
0.41
0.40
4
45
A
LEU
0.94
0.70
0.16
10
48
A
HIS
1.00
0.60
0.24
10
49
A
MET
0.69
0.66
0.27
10
50
A
LYS
0.76
0.25
0.62
1
52
A
LYS
0.95
0.25
0.70
8
53
A
ALA
0.83
0.38
0.51
10
54
A
HIS
0.89
0.60
0.49
10
55
A
SER
0.86
0.36
0.47
4
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.48
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
8
13
A
LYS
0.53
0.25
0.65
8
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.56
1
16
A
MET
0.41
0.66
0.39
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.53
1
19
A
LYS
0.38
0.25
0.39
1
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.38
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.09
2
24
A
HIS
1.00
0.60
0.40
10
25
A
THR
0.86
0.33
0.54
10
26
A
ASP
0.94
0.32
0.60
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.24
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.37
9
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.27
9
33
A
THR
0.41
0.33
0.53
9
34
A
TYR
0.70
0.80
0.53
9
35
A
CYS
1.00
0.64
0.48
9
36
A
ASN
0.80
0.39
0.60
9
37
A
PHE
0.80
1.00
0.33
9
38
A
SER
0.68
0.36
0.19
8
39
A
PHE
0.97
1.00
0.00
9
42
A
LYS
0.66
0.25
0.52
2
43
A
GLY
0.70
0.41
0.40
6
45
A
LEU
0.94
0.70
0.21
9
48
A
HIS
1.00
0.60
0.22
9
49
A
MET
0.69
0.66
0.30
9
51
A
SER
0.70
0.36
0.49
1
52
A
LYS
0.95
0.25
0.71
6
53
A
ALA
0.83
0.38
0.53
9
54
A
HIS
0.89
0.60
0.47
9
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.74
9
57
A
LYS
0.04
0.25
0.74
9
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.69
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.59
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.68
5
13
A
LYS
0.53
0.25
0.65
5
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.24
10
29
A
PRO
1.00
0.47
0.48
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.52
1
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.54
6
43
A
GLY
0.70
0.41
0.44
9
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.32
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.60
8
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.58
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.52
10
7
A
CYS
1.00
0.64
0.43
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
6
13
A
LYS
0.53
0.25
0.66
5
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
1
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
8
22
A
ARG
0.86
0.51
0.47
10
24
A
HIS
1.00
0.60
0.30
10
25
A
THR
0.86
0.33
0.48
10
26
A
ASP
0.94
0.32
0.59
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.22
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.53
4
43
A
GLY
0.70
0.41
0.44
10
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.72
5
53
A
ALA
0.83
0.38
0.57
3
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.68
1
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.62
10
6
A
GLU
0.74
0.33
0.48
10
7
A
CYS
1.00
0.64
0.39
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
5
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
5
16
A
MET
0.41
0.66
0.50
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.51
10
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.22
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.32
10
38
A
SER
0.68
0.36
0.23
5
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
5
43
A
GLY
0.70
0.41
0.46
7
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.31
10
51
A
SER
0.70
0.36
0.57
3
52
A
LYS
0.95
0.25
0.72
9
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
3
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.70
7
13
A
LYS
0.53
0.25
0.66
4
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.45
10
28
A
ARG
0.79
0.51
0.30
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.52
3
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.17
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.30
9
52
A
LYS
0.95
0.25
0.72
4
53
A
ALA
0.83
0.38
0.58
9
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.53
1
56
A
LYS
0.82
0.25
0.76
10
57
A
LYS
0.04
0.25
0.66
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.58
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.57
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
8
13
A
LYS
0.53
0.25
0.64
3
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
1
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.46
10
24
A
HIS
1.00
0.60
0.35
10
25
A
THR
0.86
0.33
0.52
10
26
A
ASP
0.94
0.32
0.61
10
27
A
VAL
0.91
0.56
0.47
10
28
A
ARG
0.79
0.51
0.31
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.31
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.18
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
8
52
A
LYS
0.95
0.25
0.75
9
53
A
ALA
0.83
0.38
0.59
10
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.49
2
56
A
LYS
0.82
0.25
0.77
10
57
A
LYS
0.04
0.25
0.68
6
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.55
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
6
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
4
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.49
10
23
A
THR
0.69
0.33
0.06
1
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.20
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.20
8
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
3
43
A
GLY
0.70
0.41
0.47
10
45
A
LEU
0.94
0.70
0.18
10
47
A
LYS
0.36
0.25
0.48
1
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.30
10
50
A
LYS
0.76
0.25
0.63
1
51
A
SER
0.70
0.36
0.57
1
52
A
LYS
0.95
0.25
0.72
7
53
A
ALA
0.83
0.38
0.56
9
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.49
5
56
A
LYS
0.82
0.25
0.65
1
57
A
LYS
0.04
0.25
0.79
2
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.66
10
13
A
LYS
0.53
0.25
0.62
9
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.54
1
16
A
MET
0.41
0.66
0.40
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.47
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
4
43
A
GLY
0.70
0.41
0.44
1
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.24
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.70
9
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.48
10
55
A
SER
0.86
0.36
0.48
6
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.73
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.68
7
14
A
PRO
0.68
0.47
0.61
10
15
A
SER
0.74
0.36
0.59
4
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.08
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.46
10
24
A
HIS
1.00
0.60
0.34
10
25
A
THR
0.86
0.33
0.50
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.50
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.60
10
34
A
TYR
0.70
0.80
0.60
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.36
10
38
A
SER
0.68
0.36
0.21
4
39
A
PHE
0.97
1.00
0.00
10
43
A
GLY
0.70
0.41
0.44
1
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
3
54
A
HIS
0.89
0.60
0.53
10
56
A
LYS
0.82
0.25
0.69
1
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
9
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
4
A
CYS
1.00
0.64
0.37
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.54
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.71
9
14
A
PRO
0.68
0.47
0.59
6
16
A
MET
0.41
0.66
0.49
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.31
10
22
A
ARG
0.86
0.51
0.47
10
23
A
THR
0.69
0.33
0.02
4
24
A
HIS
1.00
0.60
0.29
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.55
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
1
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.26
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.59
1
52
A
LYS
0.95
0.25
0.71
2
53
A
ALA
0.83
0.38
0.49
9
54
A
HIS
0.89
0.60
0.49
10
57
A
LYS
0.04
0.25
0.77
8
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
5
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
2
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.35
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.05
1
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.44
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.35
10
38
A
SER
0.68
0.36
0.21
1
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.56
5
43
A
GLY
0.70
0.41
0.42
6
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.26
10
52
A
LYS
0.95
0.25
0.71
9
53
A
ALA
0.83
0.38
0.51
6
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.67
1
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.50
10
7
A
CYS
1.00
0.64
0.37
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.29
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.59
4
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
23
A
THR
0.69
0.33
0.07
1
24
A
HIS
1.00
0.60
0.27
10
25
A
THR
0.86
0.33
0.48
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.13
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.30
10
38
A
SER
0.68
0.36
0.18
7
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.60
9
43
A
GLY
0.70
0.41
0.47
7
45
A
LEU
0.94
0.70
0.22
10
48
A
HIS
1.00
0.60
0.22
10
49
A
MET
0.69
0.66
0.29
10
53
A
ALA
0.83
0.38
0.49
9
54
A
HIS
0.89
0.60
0.48
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
7
13
A
LYS
0.53
0.25
0.66
9
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.58
4
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.23
10
18
A
LYS
0.54
0.25
0.51
2
19
A
LYS
0.38
0.25
0.43
2
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.34
10
22
A
ARG
0.86
0.51
0.51
10
23
A
THR
0.69
0.33
0.07
2
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.58
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.25
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
8
33
A
THR
0.41
0.33
0.55
8
34
A
TYR
0.70
0.80
0.57
8
35
A
CYS
1.00
0.64
0.52
8
36
A
ASN
0.80
0.39
0.61
8
37
A
PHE
0.80
1.00
0.34
10
38
A
SER
0.68
0.36
0.22
10
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.20
2
41
A
THR
0.59
0.33
0.27
2
43
A
GLY
0.70
0.41
0.46
6
45
A
LEU
0.94
0.70
0.21
8
48
A
HIS
1.00
0.60
0.25
8
49
A
MET
0.69
0.66
0.33
8
51
A
SER
0.70
0.36
0.59
2
52
A
LYS
0.95
0.25
0.73
5
53
A
ALA
0.83
0.38
0.49
8
54
A
HIS
0.89
0.60
0.51
8
56
A
LYS
0.82
0.25
0.72
7
57
A
LYS
0.04
0.25
0.77
8
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.34
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.41
10
28
A
ARG
0.79
0.51
0.21
10
29
A
PRO
1.00
0.47
0.47
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.36
10
38
A
SER
0.68
0.36
0.20
5
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.19
10
48
A
HIS
1.00
0.60
0.27
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.74
7
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.49
4
56
A
LYS
0.82
0.25
0.71
3
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.37
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.69
6
13
A
LYS
0.53
0.25
0.64
4
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.36
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.28
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
42
A
LYS
0.66
0.25
0.57
1
43
A
GLY
0.70
0.41
0.46
5
45
A
LEU
0.94
0.70
0.20
10
48
A
HIS
1.00
0.60
0.25
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
2
53
A
ALA
0.83
0.38
0.56
8
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.52
3
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
6