Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1BBO chain A sc3

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
4
A
CYS
1.00
0.64
0.39
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
21
A
ILE
0.73
0.64
0.33
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
52
A
LYS
0.95
0.25
0.74
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.73
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.40
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
24
A
HIS
1.00
0.60
0.31
10
26
A
ASP
0.94
0.32
0.58
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.22
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.65
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.48
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.43
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.48
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.38
10
25
A
THR
0.86
0.33
0.53
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.26
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.73
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.49
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.57
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.21
10
19
A
LYS
0.38
0.25
0.44
10
20
A
HIS
1.00
0.60
0.04
10
24
A
HIS
1.00
0.60
0.27
10
28
A
ARG
0.79
0.51
0.18
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
10
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.52
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.36
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.54
10
27
A
VAL
0.91
0.56
0.46
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.72
10
54
A
HIS
0.89
0.60
0.50
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.25
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.72
10
27
A
VAL
0.91
0.56
0.47
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.45
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
51
A
SER
0.70
0.36
0.53
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.48
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.70
10
1
A
LYS
0.00
0.25
0.69
1
2
A
TYR
0.78
0.80
0.51
1
3
A
ILE
0.59
0.64
0.56
1
5
A
GLU
0.40
0.33
0.65
1
8
A
GLY
0.84
0.41
0.50
1
9
A
ILE
0.76
0.64
0.32
1
10
A
ARG
0.68
0.51
0.66
1
12
A
LYS
0.53
0.25
0.68
1
13
A
LYS
0.53
0.25
0.67
1
14
A
PRO
0.68
0.47
0.58
1
15
A
SER
0.74
0.36
0.58
1
16
A
MET
0.41
0.66
0.51
1
17
A
LEU
0.87
0.70
0.22
1
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.57
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.24
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.67
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.66
10
57
A
LYS
0.04
0.25
0.80
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
8
A
GLY
0.84
0.41
0.48
10
9
A
ILE
0.76
0.64
0.26
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.24
10
24
A
HIS
1.00
0.60
0.30
10
27
A
VAL
0.91
0.56
0.48
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
8
A
GLY
0.84
0.41
0.51
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.21
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.32
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.69
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.72
9
2
A
TYR
0.78
0.80
0.51
9
3
A
ILE
0.59
0.64
0.52
9
5
A
GLU
0.40
0.33
0.66
9
6
A
GLU
0.74
0.33
0.58
9
7
A
CYS
1.00
0.64
0.46
9
8
A
GLY
0.84
0.41
0.56
9
9
A
ILE
0.76
0.64
0.35
9
10
A
ARG
0.68
0.51
0.65
9
12
A
LYS
0.53
0.25
0.68
9
13
A
LYS
0.53
0.25
0.65
9
14
A
PRO
0.68
0.47
0.59
9
17
A
LEU
0.87
0.70
0.22
9
18
A
LYS
0.54
0.25
0.53
9
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.43
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.27
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.54
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.54
10
56
A
LYS
0.82
0.25
0.68
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.51
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
30
A
TYR
0.81
0.80
0.34
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
17
A
LEU
0.87
0.70
0.23
10
26
A
ASP
0.94
0.32
0.58
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.58
10
37
A
PHE
0.80
1.00
0.28
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.23
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.62
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.64
10
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.41
10
17
A
LEU
0.87
0.70
0.21
10
21
A
ILE
0.73
0.64
0.33
10
23
A
THR
0.69
0.33
0.05
10
24
A
HIS
1.00
0.60
0.39
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.26
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.37
10
39
A
PHE
0.97
1.00
0.00
10
41
A
THR
0.59
0.33
0.18
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.70
10
53
A
ALA
0.83
0.38
0.51
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.48
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.39
10
17
A
LEU
0.87
0.70
0.25
10
21
A
ILE
0.73
0.64
0.38
10
24
A
HIS
1.00
0.60
0.40
10
26
A
ASP
0.94
0.32
0.60
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.47
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.69
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.59
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.50
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.32
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.60
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
10
51
A
SER
0.70
0.36
0.52
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.51
10
56
A
LYS
0.82
0.25
0.68
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.62
10
6
A
GLU
0.74
0.33
0.48
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
10
16
A
MET
0.41
0.66
0.50
10
17
A
LEU
0.87
0.70
0.21
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.32
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.70
9
2
A
TYR
0.78
0.80
0.51
9
3
A
ILE
0.59
0.64
0.56
9
5
A
GLU
0.40
0.33
0.67
9
6
A
GLU
0.74
0.33
0.60
9
7
A
CYS
1.00
0.64
0.49
9
8
A
GLY
0.84
0.41
0.56
9
9
A
ILE
0.76
0.64
0.34
9
10
A
ARG
0.68
0.51
0.64
9
12
A
LYS
0.53
0.25
0.70
9
13
A
LYS
0.53
0.25
0.66
9
14
A
PRO
0.68
0.47
0.59
9
16
A
MET
0.41
0.66
0.44
9
17
A
LEU
0.87
0.70
0.22
9
21
A
ILE
0.73
0.64
0.33
9
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.76
10
57
A
LYS
0.04
0.25
0.66
10
27
A
VAL
0.91
0.56
0.47
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.31
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.54
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.59
10
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.77
10
57
A
LYS
0.04
0.25
0.68
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.55
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.65
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.66
10
13
A
LYS
0.53
0.25
0.62
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.40
10
17
A
LEU
0.87
0.70
0.21
10
24
A
HIS
1.00
0.60
0.37
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.47
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.20
10
41
A
THR
0.59
0.33
0.24
10
52
A
LYS
0.95
0.25
0.70
10
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.48
10
56
A
LYS
0.82
0.25
0.66
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.73
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.68
10
14
A
PRO
0.68
0.47
0.61
10
15
A
SER
0.74
0.36
0.59
10
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.60
10
34
A
TYR
0.70
0.80
0.60
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.36
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
4
A
CYS
1.00
0.64
0.37
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.54
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.49
10
17
A
LEU
0.87
0.70
0.22
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.70
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
21
A
ILE
0.73
0.64
0.35
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.26
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.67
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.50
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.29
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.69
10
54
A
HIS
0.89
0.60
0.48
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.23
10
22
A
ARG
0.86
0.51
0.51
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.33
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.73
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.54
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
21
A
ILE
0.73
0.64
0.34
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.36
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.74
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.37
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.64
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
17
A
LEU
0.87
0.70
0.22
10
21
A
ILE
0.73
0.64
0.33
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
52
A
LYS
0.95
0.25
0.74
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.73
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.40
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
24
A
HIS
1.00
0.60
0.31
10
26
A
ASP
0.94
0.32
0.58
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.22
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.65
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.48
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.43
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.48
10
22
A
ARG
0.86
0.51
0.45
10
24
A
HIS
1.00
0.60
0.38
10
25
A
THR
0.86
0.33
0.53
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
28
A
ARG
0.79
0.51
0.26
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.73
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.49
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.57
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.21
10
19
A
LYS
0.38
0.25
0.44
10
20
A
HIS
1.00
0.60
0.04
10
24
A
HIS
1.00
0.60
0.27
10
28
A
ARG
0.79
0.51
0.18
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
10
54
A
HIS
0.89
0.60
0.52
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.69
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.52
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.36
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.37
10
25
A
THR
0.86
0.33
0.54
10
27
A
VAL
0.91
0.56
0.46
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.72
10
54
A
HIS
0.89
0.60
0.50
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.25
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.72
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.56
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.53
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.42
10
17
A
LEU
0.87
0.70
0.22
10
18
A
LYS
0.54
0.25
0.50
10
20
A
HIS
1.00
0.60
0.05
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.35
10
25
A
THR
0.86
0.33
0.52
10
27
A
VAL
0.91
0.56
0.47
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.31
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
51
A
SER
0.70
0.36
0.53
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.48
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.70
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.57
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.24
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.67
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.66
10
57
A
LYS
0.04
0.25
0.80
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.49
10
8
A
GLY
0.84
0.41
0.48
10
9
A
ILE
0.76
0.64
0.26
10
10
A
ARG
0.68
0.51
0.61
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.24
10
24
A
HIS
1.00
0.60
0.30
10
27
A
VAL
0.91
0.56
0.48
10
29
A
PRO
1.00
0.47
0.53
10
30
A
TYR
0.81
0.80
0.40
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.29
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.47
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
5
A
GLU
0.40
0.33
0.64
10
8
A
GLY
0.84
0.41
0.51
10
9
A
ILE
0.76
0.64
0.30
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.21
10
30
A
TYR
0.81
0.80
0.41
10
31
A
HIS
0.58
0.60
0.46
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.32
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.69
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.72
8
2
A
TYR
0.78
0.80
0.51
8
3
A
ILE
0.59
0.64
0.52
8
5
A
GLU
0.40
0.33
0.66
8
6
A
GLU
0.74
0.33
0.58
8
7
A
CYS
1.00
0.64
0.46
8
8
A
GLY
0.84
0.41
0.56
8
9
A
ILE
0.76
0.64
0.35
8
10
A
ARG
0.68
0.51
0.65
8
12
A
LYS
0.53
0.25
0.68
8
13
A
LYS
0.53
0.25
0.65
8
14
A
PRO
0.68
0.47
0.59
8
17
A
LEU
0.87
0.70
0.22
8
18
A
LYS
0.54
0.25
0.53
8
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.43
10
33
A
THR
0.41
0.33
0.56
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.27
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.55
10
54
A
HIS
0.89
0.60
0.54
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.60
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.53
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.28
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.54
10
56
A
LYS
0.82
0.25
0.68
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.51
10
21
A
ILE
0.73
0.64
0.33
10
22
A
ARG
0.86
0.51
0.48
10
24
A
HIS
1.00
0.60
0.39
10
25
A
THR
0.86
0.33
0.51
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.42
10
30
A
TYR
0.81
0.80
0.34
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.56
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.64
10
6
A
GLU
0.74
0.33
0.53
10
7
A
CYS
1.00
0.64
0.44
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
17
A
LEU
0.87
0.70
0.23
10
26
A
ASP
0.94
0.32
0.58
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.58
10
37
A
PHE
0.80
1.00
0.28
10
39
A
PHE
0.97
1.00
0.00
10
45
A
LEU
0.94
0.70
0.23
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.73
10
53
A
ALA
0.83
0.38
0.54
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.75
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.62
10
7
A
CYS
1.00
0.64
0.53
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.64
10
14
A
PRO
0.68
0.47
0.57
10
16
A
MET
0.41
0.66
0.41
10
17
A
LEU
0.87
0.70
0.21
10
21
A
ILE
0.73
0.64
0.33
10
23
A
THR
0.69
0.33
0.05
10
24
A
HIS
1.00
0.60
0.39
10
27
A
VAL
0.91
0.56
0.40
10
28
A
ARG
0.79
0.51
0.26
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.37
10
39
A
PHE
0.97
1.00
0.00
10
41
A
THR
0.59
0.33
0.18
10
49
A
MET
0.69
0.66
0.27
10
52
A
LYS
0.95
0.25
0.70
10
53
A
ALA
0.83
0.38
0.51
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.61
10
7
A
CYS
1.00
0.64
0.48
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.39
10
17
A
LEU
0.87
0.70
0.25
10
18
A
LYS
0.54
0.25
0.53
10
20
A
HIS
1.00
0.60
0.07
10
21
A
ILE
0.73
0.64
0.38
10
22
A
ARG
0.86
0.51
0.51
10
24
A
HIS
1.00
0.60
0.40
10
25
A
THR
0.86
0.33
0.54
10
26
A
ASP
0.94
0.32
0.60
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
49
A
MET
0.69
0.66
0.30
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.47
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.74
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.69
10
6
A
GLU
0.74
0.33
0.63
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.59
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.68
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.21
10
18
A
LYS
0.54
0.25
0.50
10
30
A
TYR
0.81
0.80
0.35
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.32
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.60
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.58
10
34
A
TYR
0.70
0.80
0.59
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
48
A
HIS
1.00
0.60
0.23
10
49
A
MET
0.69
0.66
0.28
10
51
A
SER
0.70
0.36
0.52
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.51
10
56
A
LYS
0.82
0.25
0.68
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.62
10
6
A
GLU
0.74
0.33
0.48
10
8
A
GLY
0.84
0.41
0.52
10
9
A
ILE
0.76
0.64
0.33
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.65
10
14
A
PRO
0.68
0.47
0.58
10
15
A
SER
0.74
0.36
0.59
10
16
A
MET
0.41
0.66
0.50
10
17
A
LEU
0.87
0.70
0.21
10
29
A
PRO
1.00
0.47
0.51
10
30
A
TYR
0.81
0.80
0.39
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
33
A
THR
0.41
0.33
0.51
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.32
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.57
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.75
10
57
A
LYS
0.04
0.25
0.74
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.60
10
7
A
CYS
1.00
0.64
0.49
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.22
10
21
A
ILE
0.73
0.64
0.33
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.28
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.58
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.53
10
56
A
LYS
0.82
0.25
0.76
10
57
A
LYS
0.04
0.25
0.66
10
27
A
VAL
0.91
0.56
0.47
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.30
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.31
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.54
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.59
10
54
A
HIS
0.89
0.60
0.54
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.77
10
57
A
LYS
0.04
0.25
0.68
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.56
10
5
A
GLU
0.40
0.33
0.67
10
6
A
GLU
0.74
0.33
0.55
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.70
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.58
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.21
10
20
A
HIS
1.00
0.60
0.06
10
21
A
ILE
0.73
0.64
0.32
10
22
A
ARG
0.86
0.51
0.49
10
24
A
HIS
1.00
0.60
0.32
10
25
A
THR
0.86
0.33
0.49
10
26
A
ASP
0.94
0.32
0.57
10
27
A
VAL
0.91
0.56
0.43
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.43
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.58
10
35
A
CYS
1.00
0.64
0.53
10
36
A
ASN
0.80
0.39
0.63
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.30
10
51
A
SER
0.70
0.36
0.57
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.55
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.65
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.49
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.34
10
10
A
ARG
0.68
0.51
0.64
10
12
A
LYS
0.53
0.25
0.66
10
13
A
LYS
0.53
0.25
0.62
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.40
10
17
A
LEU
0.87
0.70
0.21
10
24
A
HIS
1.00
0.60
0.37
10
27
A
VAL
0.91
0.56
0.43
10
28
A
ARG
0.79
0.51
0.26
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.36
10
31
A
HIS
0.58
0.60
0.41
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.53
10
35
A
CYS
1.00
0.64
0.47
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
40
A
LYS
0.57
0.25
0.20
10
41
A
THR
0.59
0.33
0.24
10
52
A
LYS
0.95
0.25
0.70
10
53
A
ALA
0.83
0.38
0.53
10
54
A
HIS
0.89
0.60
0.48
10
56
A
LYS
0.82
0.25
0.66
10
57
A
LYS
0.04
0.25
0.79
10
1
A
LYS
0.00
0.25
0.73
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.38
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.68
10
14
A
PRO
0.68
0.47
0.61
10
15
A
SER
0.74
0.36
0.59
10
16
A
MET
0.41
0.66
0.47
10
17
A
LEU
0.87
0.70
0.23
10
30
A
TYR
0.81
0.80
0.38
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.32
10
33
A
THR
0.41
0.33
0.60
10
34
A
TYR
0.70
0.80
0.60
10
35
A
CYS
1.00
0.64
0.54
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.36
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.75
10
53
A
ALA
0.83
0.38
0.52
10
54
A
HIS
0.89
0.60
0.53
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.69
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.53
10
4
A
CYS
1.00
0.64
0.37
10
5
A
GLU
0.40
0.33
0.65
10
6
A
GLU
0.74
0.33
0.54
10
7
A
CYS
1.00
0.64
0.46
10
8
A
GLY
0.84
0.41
0.56
10
9
A
ILE
0.76
0.64
0.36
10
10
A
ARG
0.68
0.51
0.65
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.49
10
17
A
LEU
0.87
0.70
0.22
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.26
10
34
A
TYR
0.70
0.80
0.54
10
35
A
CYS
1.00
0.64
0.49
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.49
10
56
A
LYS
0.82
0.25
0.70
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.71
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.54
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.54
10
9
A
ILE
0.76
0.64
0.31
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.67
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
15
A
SER
0.74
0.36
0.57
10
16
A
MET
0.41
0.66
0.44
10
17
A
LEU
0.87
0.70
0.23
10
21
A
ILE
0.73
0.64
0.35
10
29
A
PRO
1.00
0.47
0.49
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.64
10
37
A
PHE
0.80
1.00
0.35
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.26
10
52
A
LYS
0.95
0.25
0.71
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.67
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.51
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.50
10
8
A
GLY
0.84
0.41
0.50
10
9
A
ILE
0.76
0.64
0.29
10
10
A
ARG
0.68
0.51
0.63
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.23
10
29
A
PRO
1.00
0.47
0.52
10
30
A
TYR
0.81
0.80
0.42
10
31
A
HIS
0.58
0.60
0.45
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.54
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.48
10
36
A
ASN
0.80
0.39
0.60
10
37
A
PHE
0.80
1.00
0.30
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.29
10
52
A
LYS
0.95
0.25
0.69
10
54
A
HIS
0.89
0.60
0.48
10
55
A
SER
0.86
0.36
0.50
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.76
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.47
10
8
A
GLY
0.84
0.41
0.55
10
9
A
ILE
0.76
0.64
0.32
10
10
A
ARG
0.68
0.51
0.62
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.66
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.23
10
22
A
ARG
0.86
0.51
0.51
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.44
10
32
A
CYS
1.00
0.64
0.29
10
33
A
THR
0.41
0.33
0.55
10
34
A
TYR
0.70
0.80
0.57
10
35
A
CYS
1.00
0.64
0.52
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.34
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.33
10
51
A
SER
0.70
0.36
0.59
10
52
A
LYS
0.95
0.25
0.73
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.54
10
56
A
LYS
0.82
0.25
0.72
10
57
A
LYS
0.04
0.25
0.77
10
1
A
LYS
0.00
0.25
0.70
10
2
A
TYR
0.78
0.80
0.52
10
3
A
ILE
0.59
0.64
0.55
10
5
A
GLU
0.40
0.33
0.68
10
6
A
GLU
0.74
0.33
0.59
10
7
A
CYS
1.00
0.64
0.51
10
8
A
GLY
0.84
0.41
0.57
10
9
A
ILE
0.76
0.64
0.35
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.71
10
13
A
LYS
0.53
0.25
0.67
10
14
A
PRO
0.68
0.47
0.59
10
16
A
MET
0.41
0.66
0.45
10
17
A
LEU
0.87
0.70
0.22
10
21
A
ILE
0.73
0.64
0.34
10
30
A
TYR
0.81
0.80
0.33
10
31
A
HIS
0.58
0.60
0.40
10
32
A
CYS
1.00
0.64
0.26
10
33
A
THR
0.41
0.33
0.52
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.51
10
36
A
ASN
0.80
0.39
0.62
10
37
A
PHE
0.80
1.00
0.36
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.74
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.52
10
55
A
SER
0.86
0.36
0.49
10
56
A
LYS
0.82
0.25
0.71
10
57
A
LYS
0.04
0.25
0.78
10
1
A
LYS
0.00
0.25
0.72
10
2
A
TYR
0.78
0.80
0.50
10
3
A
ILE
0.59
0.64
0.57
10
5
A
GLU
0.40
0.33
0.66
10
6
A
GLU
0.74
0.33
0.58
10
7
A
CYS
1.00
0.64
0.50
10
8
A
GLY
0.84
0.41
0.58
10
9
A
ILE
0.76
0.64
0.37
10
10
A
ARG
0.68
0.51
0.66
10
12
A
LYS
0.53
0.25
0.69
10
13
A
LYS
0.53
0.25
0.64
10
14
A
PRO
0.68
0.47
0.60
10
16
A
MET
0.41
0.66
0.46
10
17
A
LEU
0.87
0.70
0.22
10
30
A
TYR
0.81
0.80
0.37
10
31
A
HIS
0.58
0.60
0.42
10
32
A
CYS
1.00
0.64
0.27
10
34
A
TYR
0.70
0.80
0.55
10
35
A
CYS
1.00
0.64
0.50
10
36
A
ASN
0.80
0.39
0.61
10
37
A
PHE
0.80
1.00
0.33
10
39
A
PHE
0.97
1.00
0.00
10
49
A
MET
0.69
0.66
0.31
10
52
A
LYS
0.95
0.25
0.72
10
53
A
ALA
0.83
0.38
0.56
10
54
A
HIS
0.89
0.60
0.51
10
55
A
SER
0.86
0.36
0.52
10
56
A
LYS
0.82
0.25
0.73
10
57
A
LYS
0.04
0.25
0.76
10