Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1BPV chain A auto

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
1
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
10
6
A
GLY
0.58
0.41
0.45
1
9
A
VAL
0.34
0.56
0.49
10
11
A
LEU
0.46
0.70
0.57
10
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.67
10
22
A
TRP
1.00
0.99
0.30
10
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.71
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
33
A
ILE
0.67
0.64
0.55
10
35
A
SER
0.67
0.36
0.50
4
36
A
TYR
0.95
0.80
0.36
10
37
A
ILE
0.45
0.64
0.31
5
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
4
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.54
10
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.63
10
55
A
ASN
0.62
0.39
0.61
10
56
A
ILE
0.50
0.64
0.38
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
59
A
ASN
0.47
0.39
0.49
10
60
A
GLU
0.41
0.33
0.52
10
61
A
PHE
0.47
1.00
0.34
10
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.39
7
75
A
ARG
0.86
0.51
0.29
10
77
A
ILE
0.61
0.64
0.32
10
80
A
ASN
0.93
0.39
0.68
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.44
10
89
A
SER
0.87
0.36
0.30
10
91
A
PRO
0.58
0.47
0.38
3
93
A
ASP
0.44
0.32
0.53
9
95
A
ILE
0.59
0.64
0.50
9
101
A
VAL
0.09
0.56
0.85
10
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.37
10
11
A
LEU
0.46
0.70
0.56
2
12
A
ASN
0.54
0.39
0.61
2
13
A
ILE
0.58
0.64
0.55
4
14
A
THR
0.58
0.33
0.66
2
15
A
ARG
0.45
0.51
0.74
4
16
A
HIS
0.57
0.60
0.69
2
17
A
THR
0.60
0.33
0.58
2
25
A
PRO
0.88
0.47
0.57
10
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.82
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.66
7
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.64
10
47
A
ARG
0.50
0.51
0.62
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.54
10
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.60
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.56
10
60
A
GLU
0.41
0.33
0.51
2
61
A
PHE
0.47
1.00
0.32
10
65
A
GLY
0.63
0.41
0.59
2
67
A
THR
0.41
0.33
0.70
2
68
A
GLU
0.82
0.33
0.78
2
69
A
ASP
0.71
0.32
0.80
2
72
A
TYR
0.98
0.80
0.45
10
73
A
GLU
0.69
0.33
0.40
8
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.33
10
80
A
ASN
0.93
0.39
0.68
7
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.34
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.39
10
95
A
ILE
0.59
0.64
0.45
10
98
A
ARG
0.31
0.51
0.80
10
99
A
ASP
0.50
0.32
0.83
2
100
A
ASP
0.31
0.32
0.75
2
101
A
VAL
0.09
0.56
0.84
10
102
A
GLU
0.08
0.33
0.76
4
103
A
ALA
0.01
0.38
0.88
10
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.67
2
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.39
10
9
A
VAL
0.34
0.56
0.47
1
10
A
PRO
0.60
0.47
0.39
8
11
A
LEU
0.46
0.70
0.56
10
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.55
8
15
A
ARG
0.45
0.51
0.73
8
16
A
HIS
0.57
0.60
0.69
2
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
35
A
SER
0.67
0.36
0.50
3
36
A
TYR
0.95
0.80
0.34
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.80
10
46
A
GLY
0.48
0.41
0.70
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.31
1
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.56
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.55
10
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.53
10
67
A
THR
0.41
0.33
0.69
2
68
A
GLU
0.82
0.33
0.78
2
69
A
ASP
0.71
0.32
0.80
2
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.42
9
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.34
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.53
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.81
8
99
A
ASP
0.50
0.32
0.84
2
100
A
ASP
0.31
0.32
0.75
3
101
A
VAL
0.09
0.56
0.85
8
103
A
ALA
0.01
0.38
0.89
8
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
9
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.58
4
12
A
ASN
0.54
0.39
0.61
4
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.75
10
16
A
HIS
0.57
0.60
0.69
10
25
A
PRO
0.88
0.47
0.58
9
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.76
10
37
A
ILE
0.45
0.64
0.36
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.60
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.44
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.33
1
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.64
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.60
10
59
A
ASN
0.47
0.39
0.48
1
60
A
GLU
0.41
0.33
0.56
2
61
A
PHE
0.47
1.00
0.36
10
64
A
SER
0.42
0.36
0.53
6
65
A
GLY
0.63
0.41
0.57
10
67
A
THR
0.41
0.33
0.69
10
68
A
GLU
0.82
0.33
0.78
10
69
A
ASP
0.71
0.32
0.81
10
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.40
9
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.33
10
81
A
ALA
0.42
0.38
0.80
10
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.65
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.48
10
90
A
GLU
0.42
0.33
0.51
9
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.78
10
99
A
ASP
0.50
0.32
0.84
10
100
A
ASP
0.31
0.32
0.76
4
101
A
VAL
0.09
0.56
0.87
10
102
A
GLU
0.08
0.33
0.87
10
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.65
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.33
10
9
A
VAL
0.34
0.56
0.47
10
10
A
PRO
0.60
0.47
0.38
5
11
A
LEU
0.46
0.70
0.56
10
12
A
ASN
0.54
0.39
0.61
2
13
A
ILE
0.58
0.64
0.55
5
14
A
THR
0.58
0.33
0.66
2
15
A
ARG
0.45
0.51
0.73
5
16
A
HIS
0.57
0.60
0.68
5
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
8
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.65
10
35
A
SER
0.67
0.36
0.48
2
36
A
TYR
0.95
0.80
0.32
10
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.40
2
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.57
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.57
10
60
A
GLU
0.41
0.33
0.53
10
61
A
PHE
0.47
1.00
0.31
10
65
A
GLY
0.63
0.41
0.55
7
67
A
THR
0.41
0.33
0.69
5
68
A
GLU
0.82
0.33
0.78
5
69
A
ASP
0.71
0.32
0.80
5
72
A
TYR
0.98
0.80
0.46
10
73
A
GLU
0.69
0.33
0.39
9
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.46
10
89
A
SER
0.87
0.36
0.30
10
90
A
GLU
0.42
0.33
0.49
10
91
A
PRO
0.58
0.47
0.36
8
95
A
ILE
0.59
0.64
0.46
10
98
A
ARG
0.31
0.51
0.80
5
99
A
ASP
0.50
0.32
0.83
5
100
A
ASP
0.31
0.32
0.72
2
101
A
VAL
0.09
0.56
0.84
5
102
A
GLU
0.08
0.33
0.80
2
103
A
ALA
0.01
0.38
0.89
5
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.37
10
6
A
GLY
0.58
0.41
0.44
8
9
A
VAL
0.34
0.56
0.47
10
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.62
5
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.70
10
22
A
TRP
1.00
0.99
0.28
10
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.73
10
34
A
THR
0.50
0.33
0.66
10
35
A
SER
0.67
0.36
0.49
8
36
A
TYR
0.95
0.80
0.31
10
37
A
ILE
0.45
0.64
0.30
10
39
A
GLU
0.81
0.33
0.24
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.44
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.40
7
52
A
ASN
0.54
0.39
0.37
3
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.57
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
59
A
ASN
0.47
0.39
0.46
9
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.34
10
65
A
GLY
0.63
0.41
0.60
7
73
A
GLU
0.69
0.33
0.39
7
75
A
ARG
0.86
0.51
0.31
10
77
A
ILE
0.61
0.64
0.32
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.51
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.46
9
98
A
ARG
0.31
0.51
0.80
10
100
A
ASP
0.31
0.32
0.76
1
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.79
3
103
A
ALA
0.01
0.38
0.88
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.66
1
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
10
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.61
10
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.75
1
16
A
HIS
0.57
0.60
0.70
1
25
A
PRO
0.88
0.47
0.60
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
10
35
A
SER
0.67
0.36
0.48
3
36
A
TYR
0.95
0.80
0.33
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.44
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.37
1
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.57
10
60
A
GLU
0.41
0.33
0.53
10
61
A
PHE
0.47
1.00
0.31
10
65
A
GLY
0.63
0.41
0.57
2
66
A
LEU
0.92
0.70
0.47
2
67
A
THR
0.41
0.33
0.71
1
68
A
GLU
0.82
0.33
0.78
1
69
A
ASP
0.71
0.32
0.81
1
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.39
8
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.31
10
90
A
GLU
0.42
0.33
0.50
10
91
A
PRO
0.58
0.47
0.37
10
95
A
ILE
0.59
0.64
0.49
10
98
A
ARG
0.31
0.51
0.76
1
99
A
ASP
0.50
0.32
0.84
1
100
A
ASP
0.31
0.32
0.75
1
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.86
10
103
A
ALA
0.01
0.38
0.77
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.35
10
9
A
VAL
0.34
0.56
0.51
2
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.58
6
12
A
ASN
0.54
0.39
0.60
6
13
A
ILE
0.58
0.64
0.54
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.70
9
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.69
8
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.78
10
34
A
THR
0.50
0.33
0.68
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.52
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.39
1
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.61
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.53
6
61
A
PHE
0.47
1.00
0.35
10
64
A
SER
0.42
0.36
0.52
9
65
A
GLY
0.63
0.41
0.58
9
67
A
THR
0.41
0.33
0.70
9
68
A
GLU
0.82
0.33
0.79
9
69
A
ASP
0.71
0.32
0.81
9
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.40
10
75
A
ARG
0.86
0.51
0.30
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.46
10
90
A
GLU
0.42
0.33
0.50
10
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.81
10
99
A
ASP
0.50
0.32
0.84
9
100
A
ASP
0.31
0.32
0.74
7
101
A
VAL
0.09
0.56
0.81
10
102
A
GLU
0.08
0.33
0.75
10
103
A
ALA
0.01
0.38
0.88
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.36
9
9
A
VAL
0.34
0.56
0.51
10
10
A
PRO
0.60
0.47
0.42
8
11
A
LEU
0.46
0.70
0.58
10
12
A
ASN
0.54
0.39
0.62
10
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.73
10
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.64
3
35
A
SER
0.67
0.36
0.48
1
37
A
ILE
0.45
0.64
0.32
10
39
A
GLU
0.81
0.33
0.25
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.64
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.43
10
49
A
LEU
0.47
0.70
0.54
10
51
A
ALA
0.63
0.38
0.36
6
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.60
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.56
8
61
A
PHE
0.47
1.00
0.37
10
65
A
GLY
0.63
0.41
0.57
5
68
A
GLU
0.82
0.33
0.78
10
69
A
ASP
0.71
0.32
0.80
10
73
A
GLU
0.69
0.33
0.41
10
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.33
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.49
10
90
A
GLU
0.42
0.33
0.49
8
91
A
PRO
0.58
0.47
0.38
10
93
A
ASP
0.44
0.32
0.53
7
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.80
10
99
A
ASP
0.50
0.32
0.84
10
100
A
ASP
0.31
0.32
0.74
8
101
A
VAL
0.09
0.56
0.87
10
102
A
GLU
0.08
0.33
0.86
10
103
A
ALA
0.01
0.38
0.76
10
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.37
9
9
A
VAL
0.34
0.56
0.49
10
10
A
PRO
0.60
0.47
0.40
10
11
A
LEU
0.46
0.70
0.55
10
12
A
ASN
0.54
0.39
0.60
9
13
A
ILE
0.58
0.64
0.53
10
15
A
ARG
0.45
0.51
0.73
10
16
A
HIS
0.57
0.60
0.69
10
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.82
10
28
A
THR
0.70
0.33
0.71
5
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.84
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.71
10
34
A
THR
0.50
0.33
0.68
10
37
A
ILE
0.45
0.64
0.33
7
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.52
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.37
6
53
A
PHE
0.53
1.00
0.67
10
54
A
SER
0.43
0.36
0.66
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.52
8
61
A
PHE
0.47
1.00
0.33
10
65
A
GLY
0.63
0.41
0.58
10
66
A
LEU
0.92
0.70
0.49
10
67
A
THR
0.41
0.33
0.71
10
68
A
GLU
0.82
0.33
0.75
10
69
A
ASP
0.71
0.32
0.80
10
70
A
ALA
0.51
0.38
0.69
9
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.40
10
75
A
ARG
0.86
0.51
0.28
10
77
A
ILE
0.61
0.64
0.31
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.56
10
88
A
PRO
0.87
0.47
0.46
10
90
A
GLU
0.42
0.33
0.49
10
91
A
PRO
0.58
0.47
0.36
10
93
A
ASP
0.44
0.32
0.53
8
94
A
ALA
0.43
0.38
0.54
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.80
10
99
A
ASP
0.50
0.32
0.82
10
100
A
ASP
0.31
0.32
0.72
8
0
A
SER
0.06
0.36
0.86
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.36
10
9
A
VAL
0.34
0.56
0.51
10
10
A
PRO
0.60
0.47
0.42
6
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.62
5
13
A
ILE
0.58
0.64
0.57
10
15
A
ARG
0.45
0.51
0.72
3
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.84
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.78
10
34
A
THR
0.50
0.33
0.68
9
35
A
SER
0.67
0.36
0.51
2
36
A
TYR
0.95
0.80
0.36
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.64
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.28
9
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.56
10
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.53
10
66
A
LEU
0.92
0.70
0.46
9
73
A
GLU
0.69
0.33
0.40
8
75
A
ARG
0.86
0.51
0.36
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.36
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.50
10
98
A
ARG
0.31
0.51
0.80
3
100
A
ASP
0.31
0.32
0.75
10
101
A
VAL
0.09
0.56
0.87
3
102
A
GLU
0.08
0.33
0.87
3
103
A
ALA
0.01
0.38
0.84
3
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.35
10
9
A
VAL
0.34
0.56
0.49
10
10
A
PRO
0.60
0.47
0.41
2
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.61
2
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.74
2
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
5
37
A
ILE
0.45
0.64
0.33
3
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.33
2
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.64
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.52
2
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.54
2
73
A
GLU
0.69
0.33
0.41
7
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.37
10
80
A
ASN
0.93
0.39
0.69
6
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.31
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.39
10
93
A
ASP
0.44
0.32
0.54
9
95
A
ILE
0.59
0.64
0.49
10
98
A
ARG
0.31
0.51
0.81
2
100
A
ASP
0.31
0.32
0.76
10
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.87
10
103
A
ALA
0.01
0.38
0.78
10
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.66
7
4
A
PRO
0.76
0.47
0.51
8
5
A
PRO
0.92
0.47
0.34
8
15
A
ARG
0.45
0.51
0.74
2
16
A
HIS
0.57
0.60
0.69
3
24
A
LYS
0.55
0.25
0.66
2
25
A
PRO
0.88
0.47
0.57
10
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.71
10
34
A
THR
0.50
0.33
0.67
1
35
A
SER
0.67
0.36
0.51
1
36
A
TYR
0.95
0.80
0.33
10
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.28
4
41
A
ARG
0.66
0.51
0.53
6
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
9
45
A
ASN
0.53
0.39
0.76
9
46
A
GLY
0.48
0.41
0.66
6
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.56
10
53
A
PHE
0.53
1.00
0.64
9
54
A
SER
0.43
0.36
0.59
9
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.57
9
60
A
GLU
0.41
0.33
0.54
3
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.52
5
65
A
GLY
0.63
0.41
0.59
3
66
A
LEU
0.92
0.70
0.47
3
67
A
THR
0.41
0.33
0.70
3
68
A
GLU
0.82
0.33
0.79
3
69
A
ASP
0.71
0.32
0.80
3
70
A
ALA
0.51
0.38
0.68
2
72
A
TYR
0.98
0.80
0.48
6
75
A
ARG
0.86
0.51
0.33
6
77
A
ILE
0.61
0.64
0.35
10
79
A
LYS
0.60
0.25
0.64
4
80
A
ASN
0.93
0.39
0.64
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.50
8
90
A
GLU
0.42
0.33
0.50
6
91
A
PRO
0.58
0.47
0.37
5
95
A
ILE
0.59
0.64
0.48
2
98
A
ARG
0.31
0.51
0.78
2
99
A
ASP
0.50
0.32
0.83
2
101
A
VAL
0.09
0.56
0.85
2
103
A
ALA
0.01
0.38
0.79
2
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.54
10
5
A
PRO
0.92
0.47
0.38
10
6
A
GLY
0.58
0.41
0.47
4
9
A
VAL
0.34
0.56
0.47
2
10
A
PRO
0.60
0.47
0.41
5
11
A
LEU
0.46
0.70
0.57
4
12
A
ASN
0.54
0.39
0.64
4
13
A
ILE
0.58
0.64
0.55
5
15
A
ARG
0.45
0.51
0.76
9
17
A
THR
0.60
0.33
0.58
4
25
A
PRO
0.88
0.47
0.61
10
26
A
GLU
0.37
0.33
0.78
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.68
2
35
A
SER
0.67
0.36
0.52
1
37
A
ILE
0.45
0.64
0.30
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.29
4
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.61
10
55
A
ASN
0.62
0.39
0.59
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.54
9
61
A
PHE
0.47
1.00
0.34
10
73
A
GLU
0.69
0.33
0.41
9
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.36
10
90
A
GLU
0.42
0.33
0.54
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.47
9
98
A
ARG
0.31
0.51
0.81
9
100
A
ASP
0.31
0.32
0.74
5
101
A
VAL
0.09
0.56
0.82
9
102
A
GLU
0.08
0.33
0.75
5
103
A
ALA
0.01
0.38
0.86
9
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.68
1
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.38
10
10
A
PRO
0.60
0.47
0.43
1
13
A
ILE
0.58
0.64
0.56
1
15
A
ARG
0.45
0.51
0.77
1
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.72
8
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
34
A
THR
0.50
0.33
0.67
10
36
A
TYR
0.95
0.80
0.35
10
37
A
ILE
0.45
0.64
0.34
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.30
4
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.61
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.66
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.53
10
61
A
PHE
0.47
1.00
0.36
10
66
A
LEU
0.92
0.70
0.48
4
72
A
TYR
0.98
0.80
0.49
10
73
A
GLU
0.69
0.33
0.43
8
75
A
ARG
0.86
0.51
0.34
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.41
6
95
A
ILE
0.59
0.64
0.51
8
98
A
ARG
0.31
0.51
0.81
8
100
A
ASP
0.31
0.32
0.76
1
101
A
VAL
0.09
0.56
0.79
8
102
A
GLU
0.08
0.33
0.76
1
103
A
ALA
0.01
0.38
0.88
8
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.67
10
3
A
ASP
0.64
0.32
0.65
10
4
A
PRO
0.76
0.47
0.49
10
5
A
PRO
0.92
0.47
0.32
10
6
A
GLY
0.58
0.41
0.44
3
9
A
VAL
0.34
0.56
0.48
10
10
A
PRO
0.60
0.47
0.39
9
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.60
5
13
A
ILE
0.58
0.64
0.53
10
14
A
THR
0.58
0.33
0.65
3
15
A
ARG
0.45
0.51
0.75
10
17
A
THR
0.60
0.33
0.56
2
25
A
PRO
0.88
0.47
0.57
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.82
10
29
A
GLY
0.86
0.41
0.81
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.77
10
32
A
LYS
0.78
0.25
0.75
10
37
A
ILE
0.45
0.64
0.31
7
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.31
6
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.63
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.57
6
60
A
GLU
0.41
0.33
0.52
6
61
A
PHE
0.47
1.00
0.31
10
65
A
GLY
0.63
0.41
0.55
6
70
A
ALA
0.51
0.38
0.67
10
73
A
GLU
0.69
0.33
0.38
9
75
A
ARG
0.86
0.51
0.28
10
77
A
ILE
0.61
0.64
0.32
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.56
10
88
A
PRO
0.87
0.47
0.45
10
89
A
SER
0.87
0.36
0.27
10
90
A
GLU
0.42
0.33
0.47
10
91
A
PRO
0.58
0.47
0.35
10
93
A
ASP
0.44
0.32
0.51
10
95
A
ILE
0.59
0.64
0.46
10
98
A
ARG
0.31
0.51
0.79
9
100
A
ASP
0.31
0.32
0.73
3
102
A
GLU
0.08
0.33
0.78
9
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.35
10
6
A
GLY
0.58
0.41
0.47
2
10
A
PRO
0.60
0.47
0.39
9
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.54
9
15
A
ARG
0.45
0.51
0.74
4
16
A
HIS
0.57
0.60
0.69
4
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.69
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.76
10
37
A
ILE
0.45
0.64
0.36
10
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.70
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.31
5
53
A
PHE
0.53
1.00
0.66
10
54
A
SER
0.43
0.36
0.65
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.57
10
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.35
10
64
A
SER
0.42
0.36
0.52
8
65
A
GLY
0.63
0.41
0.56
4
67
A
THR
0.41
0.33
0.69
4
68
A
GLU
0.82
0.33
0.78
4
69
A
ASP
0.71
0.32
0.80
4
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.41
10
75
A
ARG
0.86
0.51
0.36
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.76
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.52
10
95
A
ILE
0.59
0.64
0.45
10
98
A
ARG
0.31
0.51
0.81
4
99
A
ASP
0.50
0.32
0.84
4
100
A
ASP
0.31
0.32
0.75
1
101
A
VAL
0.09
0.56
0.86
9
102
A
GLU
0.08
0.33
0.85
9
103
A
ALA
0.01
0.38
0.76
9
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.35
9
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.55
1
14
A
THR
0.58
0.33
0.67
2
15
A
ARG
0.45
0.51
0.73
3
16
A
HIS
0.57
0.60
0.70
3
17
A
THR
0.60
0.33
0.59
3
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
10
35
A
SER
0.67
0.36
0.50
4
36
A
TYR
0.95
0.80
0.33
10
37
A
ILE
0.45
0.64
0.33
6
39
A
GLU
0.81
0.33
0.26
9
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.34
3
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.54
9
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.53
10
65
A
GLY
0.63
0.41
0.61
3
66
A
LEU
0.92
0.70
0.46
5
67
A
THR
0.41
0.33
0.68
3
68
A
GLU
0.82
0.33
0.78
3
69
A
ASP
0.71
0.32
0.80
3
72
A
TYR
0.98
0.80
0.46
10
73
A
GLU
0.69
0.33
0.40
8
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.33
10
81
A
ALA
0.42
0.38
0.76
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.75
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.56
10
88
A
PRO
0.87
0.47
0.46
10
89
A
SER
0.87
0.36
0.32
10
91
A
PRO
0.58
0.47
0.38
9
98
A
ARG
0.31
0.51
0.81
3
99
A
ASP
0.50
0.32
0.82
3
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.36
10
6
A
GLY
0.58
0.41
0.47
4
10
A
PRO
0.60
0.47
0.44
5
11
A
LEU
0.46
0.70
0.60
1
12
A
ASN
0.54
0.39
0.62
1
13
A
ILE
0.58
0.64
0.56
5
15
A
ARG
0.45
0.51
0.76
5
25
A
PRO
0.88
0.47
0.62
10
26
A
GLU
0.37
0.33
0.79
10
27
A
TYR
0.43
0.80
0.84
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.65
10
35
A
SER
0.67
0.36
0.50
10
36
A
TYR
0.95
0.80
0.34
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.52
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
9
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.34
7
53
A
PHE
0.53
1.00
0.67
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.66
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.34
10
65
A
GLY
0.63
0.41
0.60
7
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
10
85
A
ILE
0.18
0.64
0.66
10
87
A
PRO
0.47
0.47
0.60
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.50
10
98
A
ARG
0.31
0.51
0.81
5
100
A
ASP
0.31
0.32
0.73
1
101
A
VAL
0.09
0.56
0.83
5
102
A
GLU
0.08
0.33
0.78
5
103
A
ALA
0.01
0.38
0.88
5
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.33
9
9
A
VAL
0.34
0.56
0.46
10
10
A
PRO
0.60
0.47
0.40
10
11
A
LEU
0.46
0.70
0.56
10
12
A
ASN
0.54
0.39
0.61
6
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.75
10
16
A
HIS
0.57
0.60
0.71
9
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.82
10
28
A
THR
0.70
0.33
0.70
8
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
1
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.52
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.74
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.39
8
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.58
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.61
10
58
A
GLU
0.46
0.33
0.60
6
60
A
GLU
0.41
0.33
0.54
7
61
A
PHE
0.47
1.00
0.32
10
65
A
GLY
0.63
0.41
0.57
10
66
A
LEU
0.92
0.70
0.45
10
67
A
THR
0.41
0.33
0.68
9
68
A
GLU
0.82
0.33
0.78
9
69
A
ASP
0.71
0.32
0.80
9
72
A
TYR
0.98
0.80
0.46
10
73
A
GLU
0.69
0.33
0.38
10
75
A
ARG
0.86
0.51
0.30
10
77
A
ILE
0.61
0.64
0.33
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.79
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.45
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.36
10
95
A
ILE
0.59
0.64
0.46
10
98
A
ARG
0.31
0.51
0.80
10
99
A
ASP
0.50
0.32
0.83
10
100
A
ASP
0.31
0.32
0.73
10
101
A
VAL
0.09
0.56
0.85
10
102
A
GLU
0.08
0.33
0.86
10
103
A
ALA
0.01
0.38
0.77
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
3
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
10
10
A
PRO
0.60
0.47
0.38
10
11
A
LEU
0.46
0.70
0.57
1
12
A
ASN
0.54
0.39
0.60
1
13
A
ILE
0.58
0.64
0.54
10
14
A
THR
0.58
0.33
0.67
3
15
A
ARG
0.45
0.51
0.73
10
16
A
HIS
0.57
0.60
0.70
6
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.82
10
28
A
THR
0.70
0.33
0.71
2
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
37
A
ILE
0.45
0.64
0.33
7
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.35
6
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.51
6
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.54
10
65
A
GLY
0.63
0.41
0.60
6
67
A
THR
0.41
0.33
0.71
6
68
A
GLU
0.82
0.33
0.78
6
69
A
ASP
0.71
0.32
0.80
6
70
A
ALA
0.51
0.38
0.69
10
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.53
9
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.80
10
99
A
ASP
0.50
0.32
0.83
6
100
A
ASP
0.31
0.32
0.72
3
101
A
VAL
0.09
0.56
0.84
10
102
A
GLU
0.08
0.33
0.78
10
103
A
ALA
0.01
0.38
0.87
10
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
6
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.38
10
10
A
PRO
0.60
0.47
0.43
6
11
A
LEU
0.46
0.70
0.57
1
12
A
ASN
0.54
0.39
0.62
1
13
A
ILE
0.58
0.64
0.57
6
14
A
THR
0.58
0.33
0.67
1
15
A
ARG
0.45
0.51
0.73
6
25
A
PRO
0.88
0.47
0.60
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.72
9
29
A
GLY
0.86
0.41
0.84
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
34
A
THR
0.50
0.33
0.68
10
35
A
SER
0.67
0.36
0.51
8
36
A
TYR
0.95
0.80
0.37
10
37
A
ILE
0.45
0.64
0.32
10
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.61
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.39
4
53
A
PHE
0.53
1.00
0.66
10
54
A
SER
0.43
0.36
0.64
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.56
10
60
A
GLU
0.41
0.33
0.51
10
61
A
PHE
0.47
1.00
0.33
10
65
A
GLY
0.63
0.41
0.59
4
70
A
ALA
0.51
0.38
0.69
8
73
A
GLU
0.69
0.33
0.41
7
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.38
10
93
A
ASP
0.44
0.32
0.55
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.80
6
100
A
ASP
0.31
0.32
0.75
1
101
A
VAL
0.09
0.56
0.87
6
102
A
GLU
0.08
0.33
0.87
6
103
A
ALA
0.01
0.38
0.80
1
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
4
4
A
PRO
0.76
0.47
0.51
10
10
A
PRO
0.60
0.47
0.41
6
11
A
LEU
0.46
0.70
0.57
3
12
A
ASN
0.54
0.39
0.61
3
13
A
ILE
0.58
0.64
0.56
6
14
A
THR
0.58
0.33
0.69
3
15
A
ARG
0.45
0.51
0.74
6
25
A
PRO
0.88
0.47
0.59
9
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.71
8
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
8
34
A
THR
0.50
0.33
0.68
9
35
A
SER
0.67
0.36
0.52
6
36
A
TYR
0.95
0.80
0.34
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.37
7
52
A
ASN
0.54
0.39
0.42
1
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.65
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
9
59
A
ASN
0.47
0.39
0.47
9
60
A
GLU
0.41
0.33
0.53
9
61
A
PHE
0.47
1.00
0.37
10
64
A
SER
0.42
0.36
0.55
9
66
A
LEU
0.92
0.70
0.46
7
73
A
GLU
0.69
0.33
0.42
8
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.47
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.50
8
98
A
ARG
0.31
0.51
0.81
8
100
A
ASP
0.31
0.32
0.73
3
101
A
VAL
0.09
0.56
0.85
8
102
A
GLU
0.08
0.33
0.80
6
103
A
ALA
0.01
0.38
0.88
8
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.72
10
3
A
ASP
0.64
0.32
0.68
9
4
A
PRO
0.76
0.47
0.54
10
5
A
PRO
0.92
0.47
0.37
10
9
A
VAL
0.34
0.56
0.49
3
11
A
LEU
0.46
0.70
0.58
10
12
A
ASN
0.54
0.39
0.62
3
13
A
ILE
0.58
0.64
0.56
5
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.69
10
25
A
PRO
0.88
0.47
0.56
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
35
A
SER
0.67
0.36
0.50
3
36
A
TYR
0.95
0.80
0.33
10
37
A
ILE
0.45
0.64
0.36
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.36
1
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.63
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.53
10
61
A
PHE
0.47
1.00
0.31
10
64
A
SER
0.42
0.36
0.52
9
70
A
ALA
0.51
0.38
0.69
10
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.40
7
75
A
ARG
0.86
0.51
0.37
10
77
A
ILE
0.61
0.64
0.36
10
80
A
ASN
0.93
0.39
0.63
10
81
A
ALA
0.42
0.38
0.76
10
82
A
ALA
0.62
0.38
0.81
10
83
A
GLY
0.98
0.41
0.75
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.67
10
87
A
PRO
0.47
0.47
0.61
10
88
A
PRO
0.87
0.47
0.52
10
89
A
SER
0.87
0.36
0.36
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.38
8
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.81
10
99
A
ASP
0.50
0.32
0.84
10
100
A
ASP
0.31
0.32
0.76
10
101
A
VAL
0.09
0.56
0.85
2
102
A
GLU
0.08
0.33
0.84
2
103
A
ALA
0.01
0.38
0.72
10
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.67
9
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.36
10
6
A
GLY
0.58
0.41
0.46
1
10
A
PRO
0.60
0.47
0.42
9
11
A
LEU
0.46
0.70
0.60
9
12
A
ASN
0.54
0.39
0.63
4
13
A
ILE
0.58
0.64
0.57
9
15
A
ARG
0.45
0.51
0.75
9
16
A
HIS
0.57
0.60
0.71
5
25
A
PRO
0.88
0.47
0.60
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.67
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.42
2
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.58
10
55
A
ASN
0.62
0.39
0.64
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
6
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.34
10
65
A
GLY
0.63
0.41
0.60
2
67
A
THR
0.41
0.33
0.69
5
68
A
GLU
0.82
0.33
0.78
5
69
A
ASP
0.71
0.32
0.81
5
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.43
10
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.46
10
89
A
SER
0.87
0.36
0.32
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.54
9
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.82
9
99
A
ASP
0.50
0.32
0.84
5
100
A
ASP
0.31
0.32
0.75
4
101
A
VAL
0.09
0.56
0.86
9
102
A
GLU
0.08
0.33
0.85
9
103
A
ALA
0.01
0.38
0.78
4
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.68
10
3
A
ASP
0.64
0.32
0.66
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.34
10
6
A
GLY
0.58
0.41
0.50
1
9
A
VAL
0.34
0.56
0.50
1
10
A
PRO
0.60
0.47
0.41
5
11
A
LEU
0.46
0.70
0.58
4
12
A
ASN
0.54
0.39
0.61
4
13
A
ILE
0.58
0.64
0.54
5
15
A
ARG
0.45
0.51
0.75
5
16
A
HIS
0.57
0.60
0.71
3
25
A
PRO
0.88
0.47
0.60
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.72
10
34
A
THR
0.50
0.33
0.66
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.77
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.41
2
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.58
2
60
A
GLU
0.41
0.33
0.50
2
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.54
4
65
A
GLY
0.63
0.41
0.63
3
66
A
LEU
0.92
0.70
0.49
3
67
A
THR
0.41
0.33
0.71
3
68
A
GLU
0.82
0.33
0.76
3
69
A
ASP
0.71
0.32
0.80
3
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.31
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.65
10
87
A
PRO
0.47
0.47
0.56
10
88
A
PRO
0.87
0.47
0.47
10
89
A
SER
0.87
0.36
0.34
10
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.76
5
99
A
ASP
0.50
0.32
0.83
3
100
A
ASP
0.31
0.32
0.75
4
101
A
VAL
0.09
0.56
0.86
5
102
A
GLU
0.08
0.33
0.86
5
103
A
ALA
0.01
0.38
0.83
5
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.83
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
3
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.36
9
9
A
VAL
0.34
0.56
0.52
5
10
A
PRO
0.60
0.47
0.43
10
11
A
LEU
0.46
0.70
0.60
9
12
A
ASN
0.54
0.39
0.64
9
13
A
ILE
0.58
0.64
0.54
10
15
A
ARG
0.45
0.51
0.75
10
16
A
HIS
0.57
0.60
0.72
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.82
10
28
A
THR
0.70
0.33
0.71
6
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.77
10
34
A
THR
0.50
0.33
0.68
2
37
A
ILE
0.45
0.64
0.34
9
39
A
GLU
0.81
0.33
0.27
10
40
A
LYS
0.61
0.25
0.37
1
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.35
8
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.65
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.54
8
61
A
PHE
0.47
1.00
0.35
10
65
A
GLY
0.63
0.41
0.57
10
66
A
LEU
0.92
0.70
0.50
10
67
A
THR
0.41
0.33
0.69
10
68
A
GLU
0.82
0.33
0.79
9
69
A
ASP
0.71
0.32
0.80
9
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.37
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.47
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.53
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.81
10
99
A
ASP
0.50
0.32
0.84
9
100
A
ASP
0.31
0.32
0.76
9
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.84
10
103
A
ALA
0.01
0.38
0.72
10
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.69
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.37
10
9
A
VAL
0.34
0.56
0.49
3
10
A
PRO
0.60
0.47
0.40
9
11
A
LEU
0.46
0.70
0.59
7
12
A
ASN
0.54
0.39
0.61
7
13
A
ILE
0.58
0.64
0.56
9
14
A
THR
0.58
0.33
0.68
7
15
A
ARG
0.45
0.51
0.75
9
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
9
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.80
10
32
A
LYS
0.78
0.25
0.74
10
33
A
ILE
0.67
0.64
0.54
10
34
A
THR
0.50
0.33
0.66
10
35
A
SER
0.67
0.36
0.52
2
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.34
5
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.64
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.54
7
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.54
7
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.76
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.61
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.36
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.51
10
98
A
ARG
0.31
0.51
0.81
9
100
A
ASP
0.31
0.32
0.74
9
101
A
VAL
0.09
0.56
0.84
9
102
A
GLU
0.08
0.33
0.76
9
103
A
ALA
0.01
0.38
0.86
9
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.65
1
4
A
PRO
0.76
0.47
0.50
10
9
A
VAL
0.34
0.56
0.49
10
10
A
PRO
0.60
0.47
0.42
7
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.61
8
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.76
9
16
A
HIS
0.57
0.60
0.68
10
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.67
10
35
A
SER
0.67
0.36
0.54
9
36
A
TYR
0.95
0.80
0.35
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.65
10
44
A
PRO
0.62
0.47
0.80
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.39
4
53
A
PHE
0.53
1.00
0.67
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.52
9
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.56
6
65
A
GLY
0.63
0.41
0.63
5
67
A
THR
0.41
0.33
0.68
2
68
A
GLU
0.82
0.33
0.75
9
69
A
ASP
0.71
0.32
0.80
9
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.43
10
75
A
ARG
0.86
0.51
0.31
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.55
5
95
A
ILE
0.59
0.64
0.49
10
98
A
ARG
0.31
0.51
0.80
9
99
A
ASP
0.50
0.32
0.84
10
100
A
ASP
0.31
0.32
0.73
10
101
A
VAL
0.09
0.56
0.85
9
102
A
GLU
0.08
0.33
0.86
9
103
A
ALA
0.01
0.38
0.78
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.65
4
4
A
PRO
0.76
0.47
0.50
10
5
A
PRO
0.92
0.47
0.32
9
9
A
VAL
0.34
0.56
0.48
10
10
A
PRO
0.60
0.47
0.39
9
11
A
LEU
0.46
0.70
0.55
10
12
A
ASN
0.54
0.39
0.59
2
13
A
ILE
0.58
0.64
0.52
10
15
A
ARG
0.45
0.51
0.76
5
16
A
HIS
0.57
0.60
0.69
5
25
A
PRO
0.88
0.47
0.57
9
26
A
GLU
0.37
0.33
0.74
9
27
A
TYR
0.43
0.80
0.82
10
28
A
THR
0.70
0.33
0.69
9
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
9
33
A
ILE
0.67
0.64
0.54
10
37
A
ILE
0.45
0.64
0.29
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.53
10
42
A
ASP
0.52
0.32
0.60
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.62
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.54
10
51
A
ALA
0.63
0.38
0.39
3
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.56
6
60
A
GLU
0.41
0.33
0.53
6
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.52
5
65
A
GLY
0.63
0.41
0.60
3
67
A
THR
0.41
0.33
0.70
5
68
A
GLU
0.82
0.33
0.77
10
69
A
ASP
0.71
0.32
0.80
10
70
A
ALA
0.51
0.38
0.68
10
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.39
10
75
A
ARG
0.86
0.51
0.30
10
77
A
ILE
0.61
0.64
0.31
10
81
A
ALA
0.42
0.38
0.77
9
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.79
10
84
A
ALA
0.28
0.38
0.73
9
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.56
10
88
A
PRO
0.87
0.47
0.49
10
90
A
GLU
0.42
0.33
0.48
9
91
A
PRO
0.58
0.47
0.36
10
95
A
ILE
0.59
0.64
0.45
10
98
A
ARG
0.31
0.51
0.81
10
99
A
ASP
0.50
0.32
0.82
5
100
A
ASP
0.31
0.32
0.73
10
101
A
VAL
0.09
0.56
0.82
10
102
A
GLU
0.08
0.33
0.76
10
103
A
ALA
0.01
0.38
0.86
10
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.66
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
10
9
A
VAL
0.34
0.56
0.48
10
10
A
PRO
0.60
0.47
0.39
10
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.61
6
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.73
10
16
A
HIS
0.57
0.60
0.69
8
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
10
37
A
ILE
0.45
0.64
0.32
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.41
5
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.56
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.63
4
58
A
GLU
0.46
0.33
0.61
7
60
A
GLU
0.41
0.33
0.53
7
61
A
PHE
0.47
1.00
0.35
10
65
A
GLY
0.63
0.41
0.57
10
67
A
THR
0.41
0.33
0.70
8
68
A
GLU
0.82
0.33
0.79
8
69
A
ASP
0.71
0.32
0.80
8
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.45
10
89
A
SER
0.87
0.36
0.30
10
90
A
GLU
0.42
0.33
0.50
10
91
A
PRO
0.58
0.47
0.39
10
93
A
ASP
0.44
0.32
0.53
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.81
10
99
A
ASP
0.50
0.32
0.83
8
100
A
ASP
0.31
0.32
0.75
5
101
A
VAL
0.09
0.56
0.83
10
102
A
GLU
0.08
0.33
0.77
10
103
A
ALA
0.01
0.38
0.87
10
0
A
SER
0.06
0.36
0.86
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.66
1
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.36
10
10
A
PRO
0.60
0.47
0.43
7
11
A
LEU
0.46
0.70
0.56
2
12
A
ASN
0.54
0.39
0.62
2
13
A
ILE
0.58
0.64
0.54
7
15
A
ARG
0.45
0.51
0.74
7
16
A
HIS
0.57
0.60
0.68
2
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.69
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.74
10
37
A
ILE
0.45
0.64
0.28
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.54
10
51
A
ALA
0.63
0.38
0.39
3
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.56
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.62
10
60
A
GLU
0.41
0.33
0.52
3
61
A
PHE
0.47
1.00
0.32
10
64
A
SER
0.42
0.36
0.52
4
65
A
GLY
0.63
0.41
0.60
2
66
A
LEU
0.92
0.70
0.48
2
67
A
THR
0.41
0.33
0.71
2
68
A
GLU
0.82
0.33
0.74
2
69
A
ASP
0.71
0.32
0.80
2
70
A
ALA
0.51
0.38
0.69
7
72
A
TYR
0.98
0.80
0.49
10
73
A
GLU
0.69
0.33
0.41
9
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.31
10
81
A
ALA
0.42
0.38
0.76
8
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.73
6
85
A
ILE
0.18
0.64
0.60
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.50
10
98
A
ARG
0.31
0.51
0.76
7
99
A
ASP
0.50
0.32
0.84
2
100
A
ASP
0.31
0.32
0.75
3
101
A
VAL
0.09
0.56
0.86
7
103
A
ALA
0.01
0.38
0.82
7
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.66
4
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.35
10
9
A
VAL
0.34
0.56
0.48
10
10
A
PRO
0.60
0.47
0.40
5
11
A
LEU
0.46
0.70
0.56
10
12
A
ASN
0.54
0.39
0.62
3
13
A
ILE
0.58
0.64
0.55
6
15
A
ARG
0.45
0.51
0.73
6
16
A
HIS
0.57
0.60
0.69
4
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.71
9
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.76
10
35
A
SER
0.67
0.36
0.50
3
36
A
TYR
0.95
0.80
0.32
10
37
A
ILE
0.45
0.64
0.32
10
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.52
10
51
A
ALA
0.63
0.38
0.39
2
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.59
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.57
10
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.32
10
65
A
GLY
0.63
0.41
0.57
6
67
A
THR
0.41
0.33
0.70
4
68
A
GLU
0.82
0.33
0.78
4
69
A
ASP
0.71
0.32
0.80
4
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.44
9
75
A
ARG
0.86
0.51
0.34
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.47
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.54
10
94
A
ALA
0.43
0.38
0.56
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.81
6
99
A
ASP
0.50
0.32
0.82
4
100
A
ASP
0.31
0.32
0.74
1
101
A
VAL
0.09
0.56
0.84
6
102
A
GLU
0.08
0.33
0.80
2
103
A
ALA
0.01
0.38
0.88
6
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.67
2
4
A
PRO
0.76
0.47
0.51
10
9
A
VAL
0.34
0.56
0.49
10
10
A
PRO
0.60
0.47
0.39
8
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.61
2
13
A
ILE
0.58
0.64
0.54
8
15
A
ARG
0.45
0.51
0.73
8
16
A
HIS
0.57
0.60
0.70
8
25
A
PRO
0.88
0.47
0.59
9
26
A
GLU
0.37
0.33
0.74
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
7
29
A
GLY
0.86
0.41
0.82
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
10
35
A
SER
0.67
0.36
0.48
1
36
A
TYR
0.95
0.80
0.32
10
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.24
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.44
10
49
A
LEU
0.47
0.70
0.54
10
51
A
ALA
0.63
0.38
0.38
3
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.59
10
55
A
ASN
0.62
0.39
0.59
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
7
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.34
10
65
A
GLY
0.63
0.41
0.59
10
66
A
LEU
0.92
0.70
0.47
10
67
A
THR
0.41
0.33
0.71
8
68
A
GLU
0.82
0.33
0.79
8
69
A
ASP
0.71
0.32
0.80
8
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.40
9
75
A
ARG
0.86
0.51
0.27
10
77
A
ILE
0.61
0.64
0.32
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.61
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.46
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.38
10
95
A
ILE
0.59
0.64
0.47
9
98
A
ARG
0.31
0.51
0.75
8
99
A
ASP
0.50
0.32
0.83
8
100
A
ASP
0.31
0.32
0.74
8
101
A
VAL
0.09
0.56
0.86
8
102
A
GLU
0.08
0.33
0.87
8
103
A
ALA
0.01
0.38
0.83
8
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.55
10
9
A
VAL
0.34
0.56
0.51
1
10
A
PRO
0.60
0.47
0.43
9
11
A
LEU
0.46
0.70
0.58
6
12
A
ASN
0.54
0.39
0.63
6
13
A
ILE
0.58
0.64
0.56
10
14
A
THR
0.58
0.33
0.66
6
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.70
2
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.68
10
37
A
ILE
0.45
0.64
0.36
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.80
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.39
10
53
A
PHE
0.53
1.00
0.67
10
54
A
SER
0.43
0.36
0.60
10
55
A
ASN
0.62
0.39
0.64
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
61
A
PHE
0.47
1.00
0.33
10
65
A
GLY
0.63
0.41
0.60
10
66
A
LEU
0.92
0.70
0.47
10
67
A
THR
0.41
0.33
0.72
2
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.35
10
81
A
ALA
0.42
0.38
0.76
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.71
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.57
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.32
10
90
A
GLU
0.42
0.33
0.52
9
91
A
PRO
0.58
0.47
0.41
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.82
10
100
A
ASP
0.31
0.32
0.75
10
101
A
VAL
0.09
0.56
0.81
10
102
A
GLU
0.08
0.33
0.72
10
103
A
ALA
0.01
0.38
0.84
10
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.69
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.34
10
6
A
GLY
0.58
0.41
0.45
1
9
A
VAL
0.34
0.56
0.45
10
10
A
PRO
0.60
0.47
0.36
8
11
A
LEU
0.46
0.70
0.54
10
12
A
ASN
0.54
0.39
0.60
6
13
A
ILE
0.58
0.64
0.53
10
15
A
ARG
0.45
0.51
0.74
8
16
A
HIS
0.57
0.60
0.71
6
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.77
10
32
A
LYS
0.78
0.25
0.74
10
37
A
ILE
0.45
0.64
0.31
10
39
A
GLU
0.81
0.33
0.27
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.64
10
48
A
TRP
0.97
0.99
0.45
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.38
4
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.61
10
55
A
ASN
0.62
0.39
0.59
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.56
4
60
A
GLU
0.41
0.33
0.52
6
61
A
PHE
0.47
1.00
0.33
10
65
A
GLY
0.63
0.41
0.54
9
67
A
THR
0.41
0.33
0.68
6
68
A
GLU
0.82
0.33
0.79
6
69
A
ASP
0.71
0.32
0.80
6
70
A
ALA
0.51
0.38
0.68
9
72
A
TYR
0.98
0.80
0.46
10
73
A
GLU
0.69
0.33
0.39
10
75
A
ARG
0.86
0.51
0.31
10
77
A
ILE
0.61
0.64
0.32
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.34
10
90
A
GLU
0.42
0.33
0.50
10
91
A
PRO
0.58
0.47
0.36
10
94
A
ALA
0.43
0.38
0.53
10
95
A
ILE
0.59
0.64
0.45
10
98
A
ARG
0.31
0.51
0.81
8
99
A
ASP
0.50
0.32
0.83
6
100
A
ASP
0.31
0.32
0.74
10
101
A
VAL
0.09
0.56
0.85
8
102
A
GLU
0.08
0.33
0.85
8
103
A
ALA
0.01
0.38
0.75
8
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.37
9
6
A
GLY
0.58
0.41
0.48
1
9
A
VAL
0.34
0.56
0.49
10
10
A
PRO
0.60
0.47
0.38
5
11
A
LEU
0.46
0.70
0.58
10
12
A
ASN
0.54
0.39
0.61
6
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.74
5
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.84
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
34
A
THR
0.50
0.33
0.67
10
37
A
ILE
0.45
0.64
0.34
10
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.65
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.35
6
53
A
PHE
0.53
1.00
0.62
10
54
A
SER
0.43
0.36
0.65
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
7
60
A
GLU
0.41
0.33
0.55
9
61
A
PHE
0.47
1.00
0.35
10
70
A
ALA
0.51
0.38
0.69
8
73
A
GLU
0.69
0.33
0.42
9
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.47
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.47
9
98
A
ARG
0.31
0.51
0.76
5
100
A
ASP
0.31
0.32
0.74
5
101
A
VAL
0.09
0.56
0.87
10
102
A
GLU
0.08
0.33
0.86
10
103
A
ALA
0.01
0.38
0.79
10
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.69
10
4
A
PRO
0.76
0.47
0.55
10
5
A
PRO
0.92
0.47
0.40
10
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.61
10
12
A
ASN
0.54
0.39
0.63
10
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.78
10
16
A
HIS
0.57
0.60
0.70
10
26
A
GLU
0.37
0.33
0.78
10
27
A
TYR
0.43
0.80
0.84
10
28
A
THR
0.70
0.33
0.72
9
29
A
GLY
0.86
0.41
0.84
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.66
10
35
A
SER
0.67
0.36
0.48
7
36
A
TYR
0.95
0.80
0.35
10
37
A
ILE
0.45
0.64
0.34
10
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.68
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.42
3
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.58
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.55
10
61
A
PHE
0.47
1.00
0.37
10
65
A
GLY
0.63
0.41
0.61
7
67
A
THR
0.41
0.33
0.70
6
68
A
GLU
0.82
0.33
0.77
6
69
A
ASP
0.71
0.32
0.81
6
72
A
TYR
0.98
0.80
0.49
10
73
A
GLU
0.69
0.33
0.44
10
75
A
ARG
0.86
0.51
0.37
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.60
10
88
A
PRO
0.87
0.47
0.47
10
89
A
SER
0.87
0.36
0.38
10
90
A
GLU
0.42
0.33
0.56
10
91
A
PRO
0.58
0.47
0.43
10
93
A
ASP
0.44
0.32
0.55
10
95
A
ILE
0.59
0.64
0.49
10
98
A
ARG
0.31
0.51
0.82
6
99
A
ASP
0.50
0.32
0.85
6
100
A
ASP
0.31
0.32
0.76
8
101
A
VAL
0.09
0.56
0.85
10
102
A
GLU
0.08
0.33
0.76
9
103
A
ALA
0.01
0.38
0.87
10
0
A
SER
0.06
0.36
0.85
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.54
10
5
A
PRO
0.92
0.47
0.40
10
9
A
VAL
0.34
0.56
0.50
10
10
A
PRO
0.60
0.47
0.40
7
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.60
8
13
A
ILE
0.58
0.64
0.54
10
15
A
ARG
0.45
0.51
0.73
5
26
A
GLU
0.37
0.33
0.79
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.72
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.77
10
35
A
SER
0.67
0.36
0.50
9
36
A
TYR
0.95
0.80
0.34
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.53
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.26
5
52
A
ASN
0.54
0.39
0.39
1
53
A
PHE
0.53
1.00
0.63
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.55
10
61
A
PHE
0.47
1.00
0.40
10
73
A
GLU
0.69
0.33
0.43
8
75
A
ARG
0.86
0.51
0.37
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.62
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.46
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.55
10
91
A
PRO
0.58
0.47
0.42
10
93
A
ASP
0.44
0.32
0.55
10
94
A
ALA
0.43
0.38
0.56
10
95
A
ILE
0.59
0.64
0.50
10
98
A
ARG
0.31
0.51
0.81
3
100
A
ASP
0.31
0.32
0.75
10
101
A
VAL
0.09
0.56
0.87
5
102
A
GLU
0.08
0.33
0.88
5
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.35
10
6
A
GLY
0.58
0.41
0.46
2
9
A
VAL
0.34
0.56
0.50
3
11
A
LEU
0.46
0.70
0.58
9
12
A
ASN
0.54
0.39
0.61
9
13
A
ILE
0.58
0.64
0.55
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.69
10
26
A
GLU
0.37
0.33
0.75
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
8
34
A
THR
0.50
0.33
0.66
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.31
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.66
10
44
A
PRO
0.62
0.47
0.80
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.33
9
52
A
ASN
0.54
0.39
0.34
1
53
A
PHE
0.53
1.00
0.61
10
54
A
SER
0.43
0.36
0.59
10
55
A
ASN
0.62
0.39
0.60
10
58
A
GLU
0.46
0.33
0.58
10
60
A
GLU
0.41
0.33
0.55
7
61
A
PHE
0.47
1.00
0.36
10
65
A
GLY
0.63
0.41
0.57
7
67
A
THR
0.41
0.33
0.68
8
68
A
GLU
0.82
0.33
0.77
10
69
A
ASP
0.71
0.32
0.80
10
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.43
10
75
A
ARG
0.86
0.51
0.38
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.61
10
88
A
PRO
0.87
0.47
0.49
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.53
9
91
A
PRO
0.58
0.47
0.41
10
94
A
ALA
0.43
0.38
0.55
9
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.76
10
99
A
ASP
0.50
0.32
0.84
10
100
A
ASP
0.31
0.32
0.76
9
101
A
VAL
0.09
0.56
0.88
10
102
A
GLU
0.08
0.33
0.88
10
103
A
ALA
0.01
0.38
0.84
10
0
A
SER
0.06
0.36
0.90
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
6
A
GLY
0.58
0.41
0.45
10
9
A
VAL
0.34
0.56
0.50
10
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.60
10
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.75
10
16
A
HIS
0.57
0.60
0.68
10
22
A
TRP
1.00
0.99
0.30
10
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
6
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.67
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.69
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.42
8
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.35
10
65
A
GLY
0.63
0.41
0.60
8
70
A
ALA
0.51
0.38
0.70
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.37
10
80
A
ASN
0.93
0.39
0.69
6
81
A
ALA
0.42
0.38
0.80
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.75
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.54
10
95
A
ILE
0.59
0.64
0.50
10
98
A
ARG
0.31
0.51
0.81
10
100
A
ASP
0.31
0.32
0.76
1
101
A
VAL
0.09
0.56
0.85
10
102
A
GLU
0.08
0.33
0.76
5
103
A
ALA
0.01
0.38
0.88
10
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.35
8
11
A
LEU
0.46
0.70
0.59
10
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.55
7
15
A
ARG
0.45
0.51
0.74
6
16
A
HIS
0.57
0.60
0.70
6
25
A
PRO
0.88
0.47
0.61
9
26
A
GLU
0.37
0.33
0.78
10
27
A
TYR
0.43
0.80
0.83
10
28
A
THR
0.70
0.33
0.70
9
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
33
A
ILE
0.67
0.64
0.52
8
34
A
THR
0.50
0.33
0.66
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.65
10
44
A
PRO
0.62
0.47
0.80
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.38
3
53
A
PHE
0.53
1.00
0.66
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.62
10
56
A
ILE
0.50
0.64
0.38
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.55
10
61
A
PHE
0.47
1.00
0.36
10
65
A
GLY
0.63
0.41
0.58
3
67
A
THR
0.41
0.33
0.69
6
68
A
GLU
0.82
0.33
0.77
6
69
A
ASP
0.71
0.32
0.80
6
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.43
9
75
A
ARG
0.86
0.51
0.33
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.75
10
84
A
ALA
0.28
0.38
0.73
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.60
10
88
A
PRO
0.87
0.47
0.48
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.54
9
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.82
10
99
A
ASP
0.50
0.32
0.85
6
100
A
ASP
0.31
0.32
0.76
1
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.84
1
103
A
ALA
0.01
0.38
0.73
7
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.54
10
5
A
PRO
0.92
0.47
0.38
10
10
A
PRO
0.60
0.47
0.39
9
11
A
LEU
0.46
0.70
0.58
1
12
A
ASN
0.54
0.39
0.62
1
13
A
ILE
0.58
0.64
0.56
9
15
A
ARG
0.45
0.51
0.76
9
16
A
HIS
0.57
0.60
0.71
1
25
A
PRO
0.88
0.47
0.58
10
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.77
10
37
A
ILE
0.45
0.64
0.34
6
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.54
10
43
A
LEU
0.53
0.70
0.62
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.68
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.47
10
49
A
LEU
0.47
0.70
0.57
10
51
A
ALA
0.63
0.38
0.36
6
53
A
PHE
0.53
1.00
0.66
10
54
A
SER
0.43
0.36
0.66
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.64
10
58
A
GLU
0.46
0.33
0.59
6
60
A
GLU
0.41
0.33
0.56
6
61
A
PHE
0.47
1.00
0.35
10
64
A
SER
0.42
0.36
0.53
6
66
A
LEU
0.92
0.70
0.48
10
73
A
GLU
0.69
0.33
0.42
9
75
A
ARG
0.86
0.51
0.38
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.41
10
95
A
ILE
0.59
0.64
0.48
9
98
A
ARG
0.31
0.51
0.80
9
100
A
ASP
0.31
0.32
0.76
9
101
A
VAL
0.09
0.56
0.88
9
103
A
ALA
0.01
0.38
0.83
9
0
A
SER
0.06
0.36
0.87
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.37
10
9
A
VAL
0.34
0.56
0.48
10
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.64
5
13
A
ILE
0.58
0.64
0.56
7
14
A
THR
0.58
0.33
0.67
1
15
A
ARG
0.45
0.51
0.73
7
16
A
HIS
0.57
0.60
0.71
4
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.84
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.70
10
35
A
SER
0.67
0.36
0.54
10
36
A
TYR
0.95
0.80
0.36
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.30
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.78
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.36
2
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.64
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.63
10
60
A
GLU
0.41
0.33
0.56
8
61
A
PHE
0.47
1.00
0.35
10
65
A
GLY
0.63
0.41
0.58
5
67
A
THR
0.41
0.33
0.71
4
68
A
GLU
0.82
0.33
0.79
4
69
A
ASP
0.71
0.32
0.81
4
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.41
9
75
A
ARG
0.86
0.51
0.36
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.34
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.40
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.82
10
99
A
ASP
0.50
0.32
0.84
4
100
A
ASP
0.31
0.32
0.76
4
101
A
VAL
0.09
0.56
0.84
10
102
A
GLU
0.08
0.33
0.74
7
103
A
ALA
0.01
0.38
0.86
10
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.53
10
10
A
PRO
0.60
0.47
0.42
8
11
A
LEU
0.46
0.70
0.59
6
12
A
ASN
0.54
0.39
0.63
6
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.69
8
25
A
PRO
0.88
0.47
0.61
10
26
A
GLU
0.37
0.33
0.79
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
37
A
ILE
0.45
0.64
0.35
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.80
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.67
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.36
7
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.63
10
55
A
ASN
0.62
0.39
0.62
10
57
A
LEU
0.37
0.70
0.63
10
58
A
GLU
0.46
0.33
0.59
5
60
A
GLU
0.41
0.33
0.56
5
61
A
PHE
0.47
1.00
0.39
10
64
A
SER
0.42
0.36
0.54
8
65
A
GLY
0.63
0.41
0.59
8
67
A
THR
0.41
0.33
0.70
8
68
A
GLU
0.82
0.33
0.77
8
69
A
ASP
0.71
0.32
0.81
8
72
A
TYR
0.98
0.80
0.49
10
73
A
GLU
0.69
0.33
0.43
10
75
A
ARG
0.86
0.51
0.34
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.79
8
82
A
ALA
0.62
0.38
0.84
10
83
A
GLY
0.98
0.41
0.78
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.55
10
91
A
PRO
0.58
0.47
0.41
10
95
A
ILE
0.59
0.64
0.51
10
98
A
ARG
0.31
0.51
0.82
10
99
A
ASP
0.50
0.32
0.84
8
100
A
ASP
0.31
0.32
0.74
8
101
A
VAL
0.09
0.56
0.84
10
102
A
GLU
0.08
0.33
0.76
10
103
A
ALA
0.01
0.38
0.88
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.52
10
5
A
PRO
0.92
0.47
0.36
9
9
A
VAL
0.34
0.56
0.48
10
10
A
PRO
0.60
0.47
0.38
8
11
A
LEU
0.46
0.70
0.57
10
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.72
8
16
A
HIS
0.57
0.60
0.68
4
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.78
10
32
A
LYS
0.78
0.25
0.74
10
34
A
THR
0.50
0.33
0.67
10
35
A
SER
0.67
0.36
0.51
8
36
A
TYR
0.95
0.80
0.32
10
37
A
ILE
0.45
0.64
0.33
10
39
A
GLU
0.81
0.33
0.26
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.77
10
46
A
GLY
0.48
0.41
0.66
10
47
A
ARG
0.50
0.51
0.65
10
48
A
TRP
0.97
0.99
0.46
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.34
2
52
A
ASN
0.54
0.39
0.39
2
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.64
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.58
9
60
A
GLU
0.41
0.33
0.54
9
61
A
PHE
0.47
1.00
0.33
10
64
A
SER
0.42
0.36
0.54
9
67
A
THR
0.41
0.33
0.67
4
68
A
GLU
0.82
0.33
0.76
4
69
A
ASP
0.71
0.32
0.79
4
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.41
9
75
A
ARG
0.86
0.51
0.32
10
77
A
ILE
0.61
0.64
0.36
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.46
10
90
A
GLU
0.42
0.33
0.51
10
91
A
PRO
0.58
0.47
0.39
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.78
8
99
A
ASP
0.50
0.32
0.84
4
100
A
ASP
0.31
0.32
0.75
4
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.87
10
103
A
ALA
0.01
0.38
0.80
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.55
10
10
A
PRO
0.60
0.47
0.42
7
11
A
LEU
0.46
0.70
0.59
5
12
A
ASN
0.54
0.39
0.63
5
13
A
ILE
0.58
0.64
0.57
7
15
A
ARG
0.45
0.51
0.72
7
16
A
HIS
0.57
0.60
0.66
10
25
A
PRO
0.88
0.47
0.62
10
26
A
GLU
0.37
0.33
0.78
10
27
A
TYR
0.43
0.80
0.84
10
28
A
THR
0.70
0.33
0.72
9
29
A
GLY
0.86
0.41
0.84
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.75
10
34
A
THR
0.50
0.33
0.69
10
35
A
SER
0.67
0.36
0.52
9
36
A
TYR
0.95
0.80
0.35
10
37
A
ILE
0.45
0.64
0.32
10
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.65
10
44
A
PRO
0.62
0.47
0.80
10
45
A
ASN
0.53
0.39
0.76
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.66
10
48
A
TRP
0.97
0.99
0.48
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.35
6
52
A
ASN
0.54
0.39
0.39
1
53
A
PHE
0.53
1.00
0.64
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.60
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.57
10
60
A
GLU
0.41
0.33
0.53
10
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.53
10
69
A
ASP
0.71
0.32
0.81
10
73
A
GLU
0.69
0.33
0.41
9
75
A
ARG
0.86
0.51
0.34
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.77
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
9
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.51
10
89
A
SER
0.87
0.36
0.35
10
90
A
GLU
0.42
0.33
0.54
9
91
A
PRO
0.58
0.47
0.41
10
95
A
ILE
0.59
0.64
0.51
10
98
A
ARG
0.31
0.51
0.81
10
100
A
ASP
0.31
0.32
0.75
5
101
A
VAL
0.09
0.56
0.85
10
102
A
GLU
0.08
0.33
0.79
7
103
A
ALA
0.01
0.38
0.90
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.85
10
2
A
ILE
0.86
0.64
0.70
10
3
A
ASP
0.64
0.32
0.68
1
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.39
10
9
A
VAL
0.34
0.56
0.50
10
10
A
PRO
0.60
0.47
0.40
5
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.56
10
25
A
PRO
0.88
0.47
0.61
10
26
A
GLU
0.37
0.33
0.78
10
27
A
TYR
0.43
0.80
0.84
10
28
A
THR
0.70
0.33
0.72
9
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.77
10
34
A
THR
0.50
0.33
0.68
9
35
A
SER
0.67
0.36
0.51
4
36
A
TYR
0.95
0.80
0.37
10
37
A
ILE
0.45
0.64
0.31
6
39
A
GLU
0.81
0.33
0.28
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.64
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.78
10
46
A
GLY
0.48
0.41
0.70
10
47
A
ARG
0.50
0.51
0.64
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.55
10
51
A
ALA
0.63
0.38
0.32
1
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.64
10
55
A
ASN
0.62
0.39
0.61
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.60
10
60
A
GLU
0.41
0.33
0.56
10
61
A
PHE
0.47
1.00
0.37
10
65
A
GLY
0.63
0.41
0.57
1
72
A
TYR
0.98
0.80
0.48
10
73
A
GLU
0.69
0.33
0.41
8
75
A
ARG
0.86
0.51
0.30
10
77
A
ILE
0.61
0.64
0.34
10
80
A
ASN
0.93
0.39
0.65
10
81
A
ALA
0.42
0.38
0.79
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.63
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.46
10
89
A
SER
0.87
0.36
0.32
10
90
A
GLU
0.42
0.33
0.54
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.56
10
94
A
ALA
0.43
0.38
0.56
10
95
A
ILE
0.59
0.64
0.47
10
98
A
ARG
0.31
0.51
0.80
4
99
A
ASP
0.50
0.32
0.76
4
0
A
SER
0.06
0.36
0.88
10
1
A
PRO
0.48
0.47
0.84
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.67
10
4
A
PRO
0.76
0.47
0.51
10
5
A
PRO
0.92
0.47
0.36
10
10
A
PRO
0.60
0.47
0.41
10
11
A
LEU
0.46
0.70
0.60
1
12
A
ASN
0.54
0.39
0.61
1
13
A
ILE
0.58
0.64
0.56
10
15
A
ARG
0.45
0.51
0.74
10
16
A
HIS
0.57
0.60
0.70
3
25
A
PRO
0.88
0.47
0.59
10
26
A
GLU
0.37
0.33
0.76
10
27
A
TYR
0.43
0.80
0.83
10
29
A
GLY
0.86
0.41
0.83
10
30
A
GLY
0.81
0.41
0.86
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
37
A
ILE
0.45
0.64
0.36
10
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.55
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.67
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.36
2
53
A
PHE
0.53
1.00
0.66
10
54
A
SER
0.43
0.36
0.63
10
55
A
ASN
0.62
0.39
0.63
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.54
6
61
A
PHE
0.47
1.00
0.34
10
64
A
SER
0.42
0.36
0.53
8
65
A
GLY
0.63
0.41
0.59
3
67
A
THR
0.41
0.33
0.70
3
68
A
GLU
0.82
0.33
0.79
3
69
A
ASP
0.71
0.32
0.81
3
72
A
TYR
0.98
0.80
0.47
10
73
A
GLU
0.69
0.33
0.42
10
75
A
ARG
0.86
0.51
0.35
10
77
A
ILE
0.61
0.64
0.34
10
81
A
ALA
0.42
0.38
0.78
10
82
A
ALA
0.62
0.38
0.83
10
83
A
GLY
0.98
0.41
0.77
10
84
A
ALA
0.28
0.38
0.74
10
85
A
ILE
0.18
0.64
0.64
10
87
A
PRO
0.47
0.47
0.58
10
88
A
PRO
0.87
0.47
0.47
10
89
A
SER
0.87
0.36
0.34
10
90
A
GLU
0.42
0.33
0.53
10
91
A
PRO
0.58
0.47
0.40
10
93
A
ASP
0.44
0.32
0.53
10
95
A
ILE
0.59
0.64
0.48
10
98
A
ARG
0.31
0.51
0.76
10
99
A
ASP
0.50
0.32
0.83
3
100
A
ASP
0.31
0.32
0.75
2
101
A
VAL
0.09
0.56
0.86
10
102
A
GLU
0.08
0.33
0.87
10
103
A
ALA
0.01
0.38
0.81
10
0
A
SER
0.06
0.36
0.89
10
1
A
PRO
0.48
0.47
0.86
10
2
A
ILE
0.86
0.64
0.71
10
3
A
ASP
0.64
0.32
0.68
10
4
A
PRO
0.76
0.47
0.53
10
5
A
PRO
0.92
0.47
0.39
10
6
A
GLY
0.58
0.41
0.48
6
9
A
VAL
0.34
0.56
0.50
10
10
A
PRO
0.60
0.47
0.43
4
11
A
LEU
0.46
0.70
0.57
10
12
A
ASN
0.54
0.39
0.62
4
13
A
ILE
0.58
0.64
0.57
10
14
A
THR
0.58
0.33
0.67
3
15
A
ARG
0.45
0.51
0.73
3
16
A
HIS
0.57
0.60
0.68
1
25
A
PRO
0.88
0.47
0.61
10
26
A
GLU
0.37
0.33
0.77
10
27
A
TYR
0.43
0.80
0.84
10
28
A
THR
0.70
0.33
0.73
4
29
A
GLY
0.86
0.41
0.84
10
30
A
GLY
0.81
0.41
0.85
10
31
A
PHE
0.62
1.00
0.79
10
32
A
LYS
0.78
0.25
0.76
10
34
A
THR
0.50
0.33
0.68
10
35
A
SER
0.67
0.36
0.52
6
36
A
TYR
0.95
0.80
0.36
10
37
A
ILE
0.45
0.64
0.33
8
39
A
GLU
0.81
0.33
0.29
10
41
A
ARG
0.66
0.51
0.56
10
43
A
LEU
0.53
0.70
0.63
10
44
A
PRO
0.62
0.47
0.79
10
45
A
ASN
0.53
0.39
0.79
10
46
A
GLY
0.48
0.41
0.70
10
47
A
ARG
0.50
0.51
0.69
10
48
A
TRP
0.97
0.99
0.49
10
49
A
LEU
0.47
0.70
0.56
10
51
A
ALA
0.63
0.38
0.35
6
53
A
PHE
0.53
1.00
0.65
10
54
A
SER
0.43
0.36
0.62
10
55
A
ASN
0.62
0.39
0.64
10
57
A
LEU
0.37
0.70
0.65
10
58
A
GLU
0.46
0.33
0.59
10
60
A
GLU
0.41
0.33
0.54
10
61
A
PHE
0.47
1.00
0.35
10
65
A
GLY
0.63
0.41
0.58
6
66
A
LEU
0.92
0.70
0.47
6
67
A
THR
0.41
0.33
0.70
1
73
A
GLU
0.69
0.33
0.42
7
75
A
ARG
0.86
0.51
0.31
10
77
A
ILE
0.61
0.64
0.37
10
81
A
ALA
0.42
0.38
0.75
10
82
A
ALA
0.62
0.38
0.82
10
83
A
GLY
0.98
0.41
0.76
10
84
A
ALA
0.28
0.38
0.72
10
85
A
ILE
0.18
0.64
0.65
10
87
A
PRO
0.47
0.47
0.59
10
88
A
PRO
0.87
0.47
0.48
10
89
A
SER
0.87
0.36
0.33
10
90
A
GLU
0.42
0.33
0.52
10
91
A
PRO
0.58
0.47
0.41
10
93
A
ASP
0.44
0.32
0.54
10
95
A
ILE
0.59
0.64
0.51
7
98
A
ARG
0.31
0.51
0.81
3
101
A
VAL
0.09
0.56
0.85
3
102
A
GLU
0.08
0.33
0.86
3
103
A
ALA
0.01
0.38
0.82
3