Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1BW5 chain A sc3

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
7
A
ARG
0.94
0.51
0.43
10
9
A
VAL
0.84
0.56
0.41
10
10
A
LEU
0.90
0.70
0.35
10
11
A
ASN
0.76
0.39
0.51
10
12
A
GLU
0.62
0.33
0.62
10
15
A
LEU
0.93
0.70
0.27
10
16
A
HIS
0.65
0.60
0.47
10
21
A
CYS
0.78
0.64
0.18
10
22
A
TYR
0.91
0.80
0.11
10
24
A
ALA
0.71
0.38
0.45
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.35
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.45
10
42
A
LEU
0.97
0.70
0.20
10
45
A
ARG
0.92
0.51
0.46
10
48
A
ARG
0.86
0.51
0.46
10
49
A
VAL
0.96
0.56
0.36
10
50
A
TRP
1.00
0.99
0.06
10
51
A
PHE
0.99
1.00
0.06
10
52
A
GLN
0.92
0.43
0.43
10
56
A
CYS
0.83
0.64
0.47
10
63
A
ILE
0.70
0.64
0.33
10
64
A
MET
0.11
0.66
0.39
10
65
A
MET
0.13
0.66
0.58
10
66
A
LYS
0.04
0.25
0.53
10
7
A
ARG
0.94
0.51
0.49
10
9
A
VAL
0.84
0.56
0.48
10
10
A
LEU
0.90
0.70
0.28
10
11
A
ASN
0.76
0.39
0.49
10
12
A
GLU
0.62
0.33
0.54
10
13
A
LYS
0.87
0.25
0.60
10
16
A
HIS
0.65
0.60
0.47
10
22
A
TYR
0.91
0.80
0.27
10
23
A
ALA
0.77
0.38
0.54
10
24
A
ALA
0.71
0.38
0.53
10
25
A
ASN
0.65
0.39
0.45
10
26
A
PRO
0.91
0.47
0.44
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.51
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.35
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.06
10
55
A
ARG
0.95
0.51
0.38
10
56
A
CYS
0.83
0.64
0.44
10
60
A
LYS
0.86
0.25
0.54
10
62
A
SER
0.81
0.36
0.52
10
63
A
ILE
0.70
0.64
0.42
10
64
A
MET
0.11
0.66
0.65
10
65
A
MET
0.13
0.66
0.63
10
66
A
LYS
0.04
0.25
0.49
10
16
A
HIS
0.65
0.60
0.45
10
19
A
ARG
0.93
0.51
0.32
10
22
A
TYR
0.91
0.80
0.07
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.58
10
32
A
MET
0.67
0.66
0.32
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.46
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.27
10
43
A
SER
0.74
0.36
0.45
10
44
A
PRO
0.92
0.47
0.42
10
45
A
ARG
0.92
0.51
0.60
10
48
A
ARG
0.86
0.51
0.44
10
49
A
VAL
0.96
0.56
0.31
10
50
A
TRP
1.00
0.99
0.01
10
51
A
PHE
0.99
1.00
0.04
10
52
A
GLN
0.92
0.43
0.41
10
55
A
ARG
0.95
0.51
0.47
10
56
A
CYS
0.83
0.64
0.55
10
61
A
ARG
0.57
0.51
0.26
10
63
A
ILE
0.70
0.64
0.39
10
64
A
MET
0.11
0.66
0.43
10
65
A
MET
0.13
0.66
0.53
10
66
A
LYS
0.04
0.25
0.60
10
9
A
VAL
0.84
0.56
0.42
10
10
A
LEU
0.90
0.70
0.19
10
11
A
ASN
0.76
0.39
0.47
10
12
A
GLU
0.62
0.33
0.60
10
16
A
HIS
0.65
0.60
0.49
10
21
A
CYS
0.78
0.64
0.25
10
22
A
TYR
0.91
0.80
0.18
10
24
A
ALA
0.71
0.38
0.62
10
26
A
PRO
0.91
0.47
0.39
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.62
10
32
A
MET
0.67
0.66
0.34
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.48
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.25
10
45
A
ARG
0.92
0.51
0.50
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.05
10
56
A
CYS
0.83
0.64
0.44
10
12
A
GLU
0.62
0.33
0.60
10
16
A
HIS
0.65
0.60
0.47
10
19
A
ARG
0.93
0.51
0.34
10
21
A
CYS
0.78
0.64
0.21
10
22
A
TYR
0.91
0.80
0.22
10
24
A
ALA
0.71
0.38
0.51
10
26
A
PRO
0.91
0.47
0.45
10
30
A
ALA
0.85
0.38
0.53
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.31
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.42
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.27
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.04
10
9
A
VAL
0.84
0.56
0.38
10
10
A
LEU
0.90
0.70
0.22
10
11
A
ASN
0.76
0.39
0.51
10
12
A
GLU
0.62
0.33
0.59
10
15
A
LEU
0.93
0.70
0.20
10
16
A
HIS
0.65
0.60
0.47
10
22
A
TYR
0.91
0.80
0.19
10
24
A
ALA
0.71
0.38
0.50
10
26
A
PRO
0.91
0.47
0.46
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.58
10
32
A
MET
0.67
0.66
0.34
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.47
10
41
A
GLY
0.83
0.41
0.55
10
42
A
LEU
0.97
0.70
0.24
10
44
A
PRO
0.92
0.47
0.42
10
45
A
ARG
0.92
0.51
0.53
10
48
A
ARG
0.86
0.51
0.44
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.06
10
55
A
ARG
0.95
0.51
0.43
10
56
A
CYS
0.83
0.64
0.47
10
59
A
LYS
0.82
0.25
0.53
10
63
A
ILE
0.70
0.64
0.23
10
64
A
MET
0.11
0.66
0.50
10
65
A
MET
0.13
0.66
0.58
10
66
A
LYS
0.04
0.25
0.67
10
11
A
ASN
0.76
0.39
0.48
10
12
A
GLU
0.62
0.33
0.58
10
16
A
HIS
0.65
0.60
0.49
10
21
A
CYS
0.78
0.64
0.25
10
22
A
TYR
0.91
0.80
0.23
10
23
A
ALA
0.77
0.38
0.51
10
24
A
ALA
0.71
0.38
0.56
10
26
A
PRO
0.91
0.47
0.44
10
27
A
ARG
0.93
0.51
0.55
10
30
A
ALA
0.85
0.38
0.53
10
31
A
LEU
0.68
0.70
0.53
10
32
A
MET
0.67
0.66
0.26
10
35
A
GLN
0.90
0.43
0.53
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.39
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.29
10
45
A
ARG
0.92
0.51
0.55
10
48
A
ARG
0.86
0.51
0.38
10
51
A
PHE
0.99
1.00
0.10
10
52
A
GLN
0.92
0.43
0.47
10
55
A
ARG
0.95
0.51
0.42
10
56
A
CYS
0.83
0.64
0.43
10
16
A
HIS
0.65
0.60
0.45
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.21
10
24
A
ALA
0.71
0.38
0.62
10
26
A
PRO
0.91
0.47
0.43
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.31
10
35
A
GLN
0.90
0.43
0.52
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.47
10
41
A
GLY
0.83
0.41
0.49
10
45
A
ARG
0.92
0.51
0.48
10
48
A
ARG
0.86
0.51
0.45
10
50
A
TRP
1.00
0.99
0.04
10
51
A
PHE
0.99
1.00
0.07
10
56
A
CYS
0.83
0.64
0.43
10
9
A
VAL
0.84
0.56
0.43
10
10
A
LEU
0.90
0.70
0.21
10
11
A
ASN
0.76
0.39
0.47
10
12
A
GLU
0.62
0.33
0.62
10
16
A
HIS
0.65
0.60
0.47
10
19
A
ARG
0.93
0.51
0.42
10
22
A
TYR
0.91
0.80
0.21
10
23
A
ALA
0.77
0.38
0.51
10
24
A
ALA
0.71
0.38
0.54
10
26
A
PRO
0.91
0.47
0.42
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.31
10
34
A
GLU
0.95
0.33
0.53
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.57
10
42
A
LEU
0.97
0.70
0.28
10
45
A
ARG
0.92
0.51
0.45
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.04
10
9
A
VAL
0.84
0.56
0.37
10
10
A
LEU
0.90
0.70
0.21
10
12
A
GLU
0.62
0.33
0.61
10
16
A
HIS
0.65
0.60
0.47
10
22
A
TYR
0.91
0.80
0.17
10
24
A
ALA
0.71
0.38
0.55
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.53
10
31
A
LEU
0.68
0.70
0.55
10
32
A
MET
0.67
0.66
0.34
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.33
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.52
10
41
A
GLY
0.83
0.41
0.57
10
42
A
LEU
0.97
0.70
0.33
10
45
A
ARG
0.92
0.51
0.51
10
48
A
ARG
0.86
0.51
0.40
10
50
A
TRP
1.00
0.99
0.06
10
51
A
PHE
0.99
1.00
0.08
10
61
A
ARG
0.57
0.51
0.34
10
63
A
ILE
0.70
0.64
0.41
10
64
A
MET
0.11
0.66
0.23
10
65
A
MET
0.13
0.66
0.53
10
66
A
LYS
0.04
0.25
0.61
10
15
A
LEU
0.93
0.70
0.24
10
16
A
HIS
0.65
0.60
0.46
10
21
A
CYS
0.78
0.64
0.26
10
22
A
TYR
0.91
0.80
0.23
10
24
A
ALA
0.71
0.38
0.58
10
25
A
ASN
0.65
0.39
0.51
10
27
A
ARG
0.93
0.51
0.51
10
31
A
LEU
0.68
0.70
0.54
10
32
A
MET
0.67
0.66
0.35
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.49
10
41
A
GLY
0.83
0.41
0.59
10
42
A
LEU
0.97
0.70
0.33
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.06
10
56
A
CYS
0.83
0.64
0.47
10
1
A
MET
0.00
0.66
0.71
10
3
A
THR
0.61
0.33
0.57
10
5
A
ARG
0.83
0.51
0.47
10
7
A
ARG
0.94
0.51
0.43
10
9
A
VAL
0.84
0.56
0.46
10
11
A
ASN
0.76
0.39
0.51
10
12
A
GLU
0.62
0.33
0.62
10
13
A
LYS
0.87
0.25
0.63
10
16
A
HIS
0.65
0.60
0.47
10
20
A
THR
0.61
0.33
0.49
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.22
10
23
A
ALA
0.77
0.38
0.54
10
24
A
ALA
0.71
0.38
0.60
10
26
A
PRO
0.91
0.47
0.40
10
27
A
ARG
0.93
0.51
0.54
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.33
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.46
10
41
A
GLY
0.83
0.41
0.55
10
42
A
LEU
0.97
0.70
0.29
10
51
A
PHE
0.99
1.00
0.06
10
56
A
CYS
0.83
0.64
0.43
10
9
A
VAL
0.84
0.56
0.48
10
10
A
LEU
0.90
0.70
0.28
10
11
A
ASN
0.76
0.39
0.49
10
12
A
GLU
0.62
0.33
0.58
10
15
A
LEU
0.93
0.70
0.21
10
16
A
HIS
0.65
0.60
0.46
10
19
A
ARG
0.93
0.51
0.42
10
21
A
CYS
0.78
0.64
0.26
10
22
A
TYR
0.91
0.80
0.15
10
27
A
ARG
0.93
0.51
0.50
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.37
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.52
10
42
A
LEU
0.97
0.70
0.23
10
45
A
ARG
0.92
0.51
0.46
10
50
A
TRP
1.00
0.99
0.01
10
51
A
PHE
0.99
1.00
0.05
10
9
A
VAL
0.84
0.56
0.41
10
11
A
ASN
0.76
0.39
0.49
10
12
A
GLU
0.62
0.33
0.64
10
15
A
LEU
0.93
0.70
0.27
10
16
A
HIS
0.65
0.60
0.47
10
21
A
CYS
0.78
0.64
0.19
10
27
A
ARG
0.93
0.51
0.50
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.31
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.51
10
42
A
LEU
0.97
0.70
0.25
10
43
A
SER
0.74
0.36
0.46
10
44
A
PRO
0.92
0.47
0.39
10
45
A
ARG
0.92
0.51
0.51
10
48
A
ARG
0.86
0.51
0.45
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.03
10
12
A
GLU
0.62
0.33
0.58
10
13
A
LYS
0.87
0.25
0.61
10
16
A
HIS
0.65
0.60
0.44
10
21
A
CYS
0.78
0.64
0.22
10
22
A
TYR
0.91
0.80
0.13
10
24
A
ALA
0.71
0.38
0.55
10
25
A
ASN
0.65
0.39
0.41
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.54
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.38
10
34
A
GLU
0.95
0.33
0.46
10
35
A
GLN
0.90
0.43
0.49
10
36
A
LEU
0.92
0.70
0.14
10
37
A
VAL
0.83
0.56
0.31
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.52
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.23
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.02
10
61
A
ARG
0.57
0.51
0.41
10
63
A
ILE
0.70
0.64
0.41
10
64
A
MET
0.11
0.66
0.29
10
65
A
MET
0.13
0.66
0.48
10
66
A
LYS
0.04
0.25
0.67
10
9
A
VAL
0.84
0.56
0.41
10
10
A
LEU
0.90
0.70
0.19
10
11
A
ASN
0.76
0.39
0.45
10
12
A
GLU
0.62
0.33
0.60
10
15
A
LEU
0.93
0.70
0.21
10
16
A
HIS
0.65
0.60
0.46
10
19
A
ARG
0.93
0.51
0.38
10
21
A
CYS
0.78
0.64
0.22
10
22
A
TYR
0.91
0.80
0.14
10
23
A
ALA
0.77
0.38
0.45
10
24
A
ALA
0.71
0.38
0.54
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.31
10
34
A
GLU
0.95
0.33
0.53
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.38
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.28
10
44
A
PRO
0.92
0.47
0.41
10
50
A
TRP
1.00
0.99
0.01
10
51
A
PHE
0.99
1.00
0.02
10
61
A
ARG
0.57
0.51
0.20
10
62
A
SER
0.81
0.36
0.41
10
63
A
ILE
0.70
0.64
0.59
10
64
A
MET
0.11
0.66
0.51
10
65
A
MET
0.13
0.66
0.63
10
66
A
LYS
0.04
0.25
0.33
10
1
A
MET
0.00
0.66
0.54
10
5
A
ARG
0.83
0.51
0.38
10
6
A
VAL
0.86
0.56
0.41
10
7
A
ARG
0.94
0.51
0.44
10
9
A
VAL
0.84
0.56
0.44
10
10
A
LEU
0.90
0.70
0.24
10
11
A
ASN
0.76
0.39
0.49
10
12
A
GLU
0.62
0.33
0.58
10
13
A
LYS
0.87
0.25
0.63
10
15
A
LEU
0.93
0.70
0.24
10
16
A
HIS
0.65
0.60
0.46
10
19
A
ARG
0.93
0.51
0.41
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.13
10
23
A
ALA
0.77
0.38
0.47
10
24
A
ALA
0.71
0.38
0.55
10
27
A
ARG
0.93
0.51
0.46
10
30
A
ALA
0.85
0.38
0.58
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.28
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.39
10
38
A
GLU
0.54
0.33
0.62
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.52
10
42
A
LEU
0.97
0.70
0.34
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.05
10
55
A
ARG
0.95
0.51
0.28
10
56
A
CYS
0.83
0.64
0.46
10
63
A
ILE
0.70
0.64
0.36
10
64
A
MET
0.11
0.66
0.34
10
65
A
MET
0.13
0.66
0.43
10
66
A
LYS
0.04
0.25
0.68
10
10
A
LEU
0.90
0.70
0.20
10
11
A
ASN
0.76
0.39
0.45
10
12
A
GLU
0.62
0.33
0.60
10
15
A
LEU
0.93
0.70
0.20
10
16
A
HIS
0.65
0.60
0.45
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.36
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.37
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.29
10
43
A
SER
0.74
0.36
0.46
10
50
A
TRP
1.00
0.99
0.01
10
21
A
CYS
0.78
0.64
0.22
10
22
A
TYR
0.91
0.80
0.16
10
24
A
ALA
0.71
0.38
0.55
10
25
A
ASN
0.65
0.39
0.45
10
26
A
PRO
0.91
0.47
0.37
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.34
10
34
A
GLU
0.95
0.33
0.48
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.51
10
42
A
LEU
0.97
0.70
0.24
10
44
A
PRO
0.92
0.47
0.41
10
45
A
ARG
0.92
0.51
0.56
10
48
A
ARG
0.86
0.51
0.45
10
49
A
VAL
0.96
0.56
0.28
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.06
10
9
A
VAL
0.84
0.56
0.43
10
10
A
LEU
0.90
0.70
0.21
10
11
A
ASN
0.76
0.39
0.47
10
12
A
GLU
0.62
0.33
0.59
10
16
A
HIS
0.65
0.60
0.44
10
21
A
CYS
0.78
0.64
0.25
10
22
A
TYR
0.91
0.80
0.20
10
24
A
ALA
0.71
0.38
0.61
10
26
A
PRO
0.91
0.47
0.43
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.30
10
34
A
GLU
0.95
0.33
0.53
10
35
A
GLN
0.90
0.43
0.46
10
37
A
VAL
0.83
0.56
0.40
10
38
A
GLU
0.54
0.33
0.62
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.38
10
43
A
SER
0.74
0.36
0.48
10
45
A
ARG
0.92
0.51
0.50
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.06
10
56
A
CYS
0.83
0.64
0.43
10
61
A
ARG
0.57
0.51
0.21
10
63
A
ILE
0.70
0.64
0.31
10
64
A
MET
0.11
0.66
0.34
10
65
A
MET
0.13
0.66
0.57
10
66
A
LYS
0.04
0.25
0.64
10
1
A
MET
0.00
0.66
0.72
10
2
A
LYS
0.65
0.25
0.52
10
3
A
THR
0.61
0.33
0.60
10
5
A
ARG
0.83
0.51
0.27
10
7
A
ARG
0.94
0.51
0.33
10
9
A
VAL
0.84
0.56
0.41
10
10
A
LEU
0.90
0.70
0.20
10
11
A
ASN
0.76
0.39
0.47
10
12
A
GLU
0.62
0.33
0.58
10
15
A
LEU
0.93
0.70
0.21
10
16
A
HIS
0.65
0.60
0.45
10
19
A
ARG
0.93
0.51
0.26
10
22
A
TYR
0.91
0.80
0.13
10
24
A
ALA
0.71
0.38
0.59
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.50
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.27
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.39
10
38
A
GLU
0.54
0.33
0.62
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.37
10
43
A
SER
0.74
0.36
0.46
10
44
A
PRO
0.92
0.47
0.40
10
45
A
ARG
0.92
0.51
0.47
10
48
A
ARG
0.86
0.51
0.40
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.07
10
55
A
ARG
0.95
0.51
0.45
10
56
A
CYS
0.83
0.64
0.45
10
63
A
ILE
0.70
0.64
0.56
10
64
A
MET
0.11
0.66
0.18
10
65
A
MET
0.13
0.66
0.49
10
66
A
LYS
0.04
0.25
0.60
10
12
A
GLU
0.62
0.33
0.58
10
15
A
LEU
0.93
0.70
0.18
10
16
A
HIS
0.65
0.60
0.48
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.26
10
23
A
ALA
0.77
0.38
0.53
10
24
A
ALA
0.71
0.38
0.57
10
25
A
ASN
0.65
0.39
0.47
10
26
A
PRO
0.91
0.47
0.43
10
27
A
ARG
0.93
0.51
0.49
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.29
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.33
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.35
10
45
A
ARG
0.92
0.51
0.49
10
48
A
ARG
0.86
0.51
0.40
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.07
10
55
A
ARG
0.95
0.51
0.44
10
56
A
CYS
0.83
0.64
0.46
10
61
A
ARG
0.57
0.51
0.24
10
63
A
ILE
0.70
0.64
0.37
10
64
A
MET
0.11
0.66
0.27
10
65
A
MET
0.13
0.66
0.57
10
66
A
LYS
0.04
0.25
0.67
10
9
A
VAL
0.84
0.56
0.42
10
10
A
LEU
0.90
0.70
0.23
10
12
A
GLU
0.62
0.33
0.61
10
16
A
HIS
0.65
0.60
0.45
10
19
A
ARG
0.93
0.51
0.30
10
22
A
TYR
0.91
0.80
0.19
10
24
A
ALA
0.71
0.38
0.55
10
25
A
ASN
0.65
0.39
0.42
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.31
10
34
A
GLU
0.95
0.33
0.49
10
35
A
GLN
0.90
0.43
0.46
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.45
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.33
10
45
A
ARG
0.92
0.51
0.56
10
48
A
ARG
0.86
0.51
0.45
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.05
10
55
A
ARG
0.95
0.51
0.44
10
56
A
CYS
0.83
0.64
0.50
10
61
A
ARG
0.57
0.51
0.24
10
63
A
ILE
0.70
0.64
0.37
10
64
A
MET
0.11
0.66
0.55
10
65
A
MET
0.13
0.66
0.55
10
66
A
LYS
0.04
0.25
0.58
10
9
A
VAL
0.84
0.56
0.43
10
10
A
LEU
0.90
0.70
0.20
10
12
A
GLU
0.62
0.33
0.47
10
16
A
HIS
0.65
0.60
0.41
10
20
A
THR
0.61
0.33
0.43
10
22
A
TYR
0.91
0.80
0.22
10
24
A
ALA
0.71
0.38
0.54
10
25
A
ASN
0.65
0.39
0.48
10
26
A
PRO
0.91
0.47
0.38
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.54
10
32
A
MET
0.67
0.66
0.30
10
34
A
GLU
0.95
0.33
0.48
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.31
10
38
A
GLU
0.54
0.33
0.58
10
39
A
MET
0.72
0.66
0.42
10
41
A
GLY
0.83
0.41
0.51
10
42
A
LEU
0.97
0.70
0.34
10
43
A
SER
0.74
0.36
0.46
10
44
A
PRO
0.92
0.47
0.38
10
45
A
ARG
0.92
0.51
0.55
10
48
A
ARG
0.86
0.51
0.46
10
51
A
PHE
0.99
1.00
0.08
10
55
A
ARG
0.95
0.51
0.43
10
56
A
CYS
0.83
0.64
0.41
10
63
A
ILE
0.70
0.64
0.29
10
64
A
MET
0.11
0.66
0.46
10
65
A
MET
0.13
0.66
0.62
10
66
A
LYS
0.04
0.25
0.44
10
10
A
LEU
0.90
0.70
0.21
10
11
A
ASN
0.76
0.39
0.47
10
12
A
GLU
0.62
0.33
0.63
10
15
A
LEU
0.93
0.70
0.23
10
16
A
HIS
0.65
0.60
0.46
10
22
A
TYR
0.91
0.80
0.16
10
24
A
ALA
0.71
0.38
0.57
10
25
A
ASN
0.65
0.39
0.36
10
26
A
PRO
0.91
0.47
0.42
10
27
A
ARG
0.93
0.51
0.54
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.55
10
32
A
MET
0.67
0.66
0.25
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.50
10
36
A
LEU
0.92
0.70
0.15
10
37
A
VAL
0.83
0.56
0.32
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.51
10
41
A
GLY
0.83
0.41
0.52
10
45
A
ARG
0.92
0.51
0.54
10
48
A
ARG
0.86
0.51
0.40
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.05
10
52
A
GLN
0.92
0.43
0.44
10
55
A
ARG
0.95
0.51
0.45
10
56
A
CYS
0.83
0.64
0.43
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.30
10
23
A
ALA
0.77
0.38
0.54
10
24
A
ALA
0.71
0.38
0.58
10
25
A
ASN
0.65
0.39
0.43
10
26
A
PRO
0.91
0.47
0.46
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.60
10
31
A
LEU
0.68
0.70
0.58
10
32
A
MET
0.67
0.66
0.33
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.45
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.37
10
43
A
SER
0.74
0.36
0.48
10
44
A
PRO
0.92
0.47
0.43
10
45
A
ARG
0.92
0.51
0.62
10
48
A
ARG
0.86
0.51
0.41
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.07
10
55
A
ARG
0.95
0.51
0.46
10
21
A
CYS
0.78
0.64
0.18
10
22
A
TYR
0.91
0.80
0.16
10
26
A
PRO
0.91
0.47
0.45
10
27
A
ARG
0.93
0.51
0.56
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.58
10
32
A
MET
0.67
0.66
0.28
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.44
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.52
10
42
A
LEU
0.97
0.70
0.33
10
45
A
ARG
0.92
0.51
0.41
10
48
A
ARG
0.86
0.51
0.41
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.06
10
55
A
ARG
0.95
0.51
0.48
10
56
A
CYS
0.83
0.64
0.47
10
9
A
VAL
0.84
0.56
0.37
10
10
A
LEU
0.90
0.70
0.21
10
22
A
TYR
0.91
0.80
0.24
10
23
A
ALA
0.77
0.38
0.53
10
24
A
ALA
0.71
0.38
0.61
10
26
A
PRO
0.91
0.47
0.44
10
27
A
ARG
0.93
0.51
0.47
10
30
A
ALA
0.85
0.38
0.60
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.53
10
35
A
GLN
0.90
0.43
0.45
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.37
10
44
A
PRO
0.92
0.47
0.43
10
45
A
ARG
0.92
0.51
0.56
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.05
10
10
A
LEU
0.90
0.70
0.22
10
15
A
LEU
0.93
0.70
0.24
10
16
A
HIS
0.65
0.60
0.45
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.60
10
31
A
LEU
0.68
0.70
0.62
10
32
A
MET
0.67
0.66
0.33
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.40
10
41
A
GLY
0.83
0.41
0.51
10
42
A
LEU
0.97
0.70
0.35
10
45
A
ARG
0.92
0.51
0.55
10
48
A
ARG
0.86
0.51
0.44
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.06
10
55
A
ARG
0.95
0.51
0.41
10
56
A
CYS
0.83
0.64
0.55
10
10
A
LEU
0.90
0.70
0.22
10
12
A
GLU
0.62
0.33
0.59
10
16
A
HIS
0.65
0.60
0.45
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.35
10
34
A
GLU
0.95
0.33
0.48
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.32
10
38
A
GLU
0.54
0.33
0.58
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.40
10
43
A
SER
0.74
0.36
0.49
10
50
A
TRP
1.00
0.99
0.00
10
22
A
TYR
0.91
0.80
0.30
10
23
A
ALA
0.77
0.38
0.55
10
24
A
ALA
0.71
0.38
0.52
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.28
10
35
A
GLN
0.90
0.43
0.46
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.36
10
10
A
LEU
0.90
0.70
0.20
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.37
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.37
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.39
10
44
A
PRO
0.92
0.47
0.42
10
48
A
ARG
0.86
0.51
0.41
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.04
10
10
A
LEU
0.90
0.70
0.22
10
12
A
GLU
0.62
0.33
0.60
10
15
A
LEU
0.93
0.70
0.21
10
16
A
HIS
0.65
0.60
0.47
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.27
10
23
A
ALA
0.77
0.38
0.53
10
24
A
ALA
0.71
0.38
0.56
10
26
A
PRO
0.91
0.47
0.45
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.60
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.29
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.45
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.35
10
43
A
SER
0.74
0.36
0.50
10
45
A
ARG
0.92
0.51
0.58
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.04
10
11
A
ASN
0.76
0.39
0.44
10
12
A
GLU
0.62
0.33
0.62
10
16
A
HIS
0.65
0.60
0.48
10
21
A
CYS
0.78
0.64
0.22
10
22
A
TYR
0.91
0.80
0.15
10
27
A
ARG
0.93
0.51
0.50
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.34
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.42
10
41
A
GLY
0.83
0.41
0.52
10
42
A
LEU
0.97
0.70
0.36
10
45
A
ARG
0.92
0.51
0.49
10
48
A
ARG
0.86
0.51
0.43
10
50
A
TRP
1.00
0.99
0.04
10
51
A
PHE
0.99
1.00
0.06
10
55
A
ARG
0.95
0.51
0.38
10
56
A
CYS
0.83
0.64
0.49
10
61
A
ARG
0.57
0.51
0.32
10
63
A
ILE
0.70
0.64
0.23
10
64
A
MET
0.11
0.66
0.52
10
65
A
MET
0.13
0.66
0.64
10
66
A
LYS
0.04
0.25
0.55
10
10
A
LEU
0.90
0.70
0.19
10
12
A
GLU
0.62
0.33
0.59
10
16
A
HIS
0.65
0.60
0.45
10
30
A
ALA
0.85
0.38
0.54
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.33
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.52
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.46
10
41
A
GLY
0.83
0.41
0.55
10
42
A
LEU
0.97
0.70
0.38
10
50
A
TRP
1.00
0.99
0.00
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.34
10
34
A
GLU
0.95
0.33
0.53
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.34
10
38
A
GLU
0.54
0.33
0.58
10
39
A
MET
0.72
0.66
0.40
10
41
A
GLY
0.83
0.41
0.52
10
42
A
LEU
0.97
0.70
0.36
10
44
A
PRO
0.92
0.47
0.46
10
45
A
ARG
0.92
0.51
0.50
10
1
A
MET
0.00
0.66
0.63
10
5
A
ARG
0.83
0.51
0.39
10
7
A
ARG
0.94
0.51
0.40
10
9
A
VAL
0.84
0.56
0.41
10
10
A
LEU
0.90
0.70
0.19
10
12
A
GLU
0.62
0.33
0.60
10
16
A
HIS
0.65
0.60
0.46
10
27
A
ARG
0.93
0.51
0.50
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.62
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.48
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.36
10
43
A
SER
0.74
0.36
0.51
10
44
A
PRO
0.92
0.47
0.42
10
45
A
ARG
0.92
0.51
0.58
10
48
A
ARG
0.86
0.51
0.41
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.05
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.19
10
23
A
ALA
0.77
0.38
0.49
10
24
A
ALA
0.71
0.38
0.62
10
26
A
PRO
0.91
0.47
0.42
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.53
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.27
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.36
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.27
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.02
10
55
A
ARG
0.95
0.51
0.38
10
56
A
CYS
0.83
0.64
0.47
10
10
A
LEU
0.90
0.70
0.18
10
11
A
ASN
0.76
0.39
0.44
10
12
A
GLU
0.62
0.33
0.58
10
16
A
HIS
0.65
0.60
0.46
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.15
10
24
A
ALA
0.71
0.38
0.59
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.54
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.38
10
35
A
GLN
0.90
0.43
0.48
10
36
A
LEU
0.92
0.70
0.13
10
37
A
VAL
0.83
0.56
0.32
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.47
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.22
10
45
A
ARG
0.92
0.51
0.47
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.01
10
16
A
HIS
0.65
0.60
0.43
10
21
A
CYS
0.78
0.64
0.20
10
22
A
TYR
0.91
0.80
0.17
10
24
A
ALA
0.71
0.38
0.51
10
26
A
PRO
0.91
0.47
0.39
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.56
10
32
A
MET
0.67
0.66
0.29
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.46
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.23
10
45
A
ARG
0.92
0.51
0.46
10
48
A
ARG
0.86
0.51
0.44
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.07
10
52
A
GLN
0.92
0.43
0.47
10
55
A
ARG
0.95
0.51
0.42
10
56
A
CYS
0.83
0.64
0.51
10
9
A
VAL
0.84
0.56
0.40
10
10
A
LEU
0.90
0.70
0.20
10
11
A
ASN
0.76
0.39
0.49
10
12
A
GLU
0.62
0.33
0.58
10
13
A
LYS
0.87
0.25
0.60
10
15
A
LEU
0.93
0.70
0.20
10
16
A
HIS
0.65
0.60
0.45
10
21
A
CYS
0.78
0.64
0.20
10
22
A
TYR
0.91
0.80
0.21
10
23
A
ALA
0.77
0.38
0.53
10
24
A
ALA
0.71
0.38
0.52
10
26
A
PRO
0.91
0.47
0.38
10
27
A
ARG
0.93
0.51
0.51
10
30
A
ALA
0.85
0.38
0.58
10
31
A
LEU
0.68
0.70
0.58
10
32
A
MET
0.67
0.66
0.28
10
34
A
GLU
0.95
0.33
0.51
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.58
10
39
A
MET
0.72
0.66
0.40
10
41
A
GLY
0.83
0.41
0.53
10
42
A
LEU
0.97
0.70
0.23
10
50
A
TRP
1.00
0.99
0.00
10
1
A
MET
0.00
0.66
0.62
10
2
A
LYS
0.65
0.25
0.57
10
3
A
THR
0.61
0.33
0.46
10
5
A
ARG
0.83
0.51
0.40
10
6
A
VAL
0.86
0.56
0.50
10
7
A
ARG
0.94
0.51
0.60
10
9
A
VAL
0.84
0.56
0.42
10
10
A
LEU
0.90
0.70
0.23
10
11
A
ASN
0.76
0.39
0.48
10
12
A
GLU
0.62
0.33
0.61
10
15
A
LEU
0.93
0.70
0.20
10
16
A
HIS
0.65
0.60
0.49
10
50
A
TRP
1.00
0.99
0.03
10
10
A
LEU
0.90
0.70
0.27
10
12
A
GLU
0.62
0.33
0.60
10
16
A
HIS
0.65
0.60
0.47
10
19
A
ARG
0.93
0.51
0.34
10
20
A
THR
0.61
0.33
0.46
10
21
A
CYS
0.78
0.64
0.23
10
22
A
TYR
0.91
0.80
0.11
10
27
A
ARG
0.93
0.51
0.47
10
29
A
ASP
0.86
0.32
0.40
10
30
A
ALA
0.85
0.38
0.54
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.50
10
37
A
VAL
0.83
0.56
0.37
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.51
10
42
A
LEU
0.97
0.70
0.29
10
50
A
TRP
1.00
0.99
0.03
10
51
A
PHE
0.99
1.00
0.03
10
56
A
CYS
0.83
0.64
0.50
10
61
A
ARG
0.57
0.51
0.49
10
62
A
SER
0.81
0.36
0.56
10
63
A
ILE
0.70
0.64
0.38
10
64
A
MET
0.11
0.66
0.47
10
65
A
MET
0.13
0.66
0.35
10
66
A
LYS
0.04
0.25
0.68
10
9
A
VAL
0.84
0.56
0.50
10
10
A
LEU
0.90
0.70
0.28
10
21
A
CYS
0.78
0.64
0.24
10
22
A
TYR
0.91
0.80
0.16
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.57
10
31
A
LEU
0.68
0.70
0.62
10
32
A
MET
0.67
0.66
0.38
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.35
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.43
10
41
A
GLY
0.83
0.41
0.56
10
42
A
LEU
0.97
0.70
0.41
10
43
A
SER
0.74
0.36
0.49
10
44
A
PRO
0.92
0.47
0.42
10
45
A
ARG
0.92
0.51
0.53
10
51
A
PHE
0.99
1.00
0.07
10
61
A
ARG
0.57
0.51
0.41
10
63
A
ILE
0.70
0.64
0.31
10
64
A
MET
0.11
0.66
0.48
10
65
A
MET
0.13
0.66
0.44
10
66
A
LYS
0.04
0.25
0.66
10
7
A
ARG
0.94
0.51
0.52
10
9
A
VAL
0.84
0.56
0.45
10
10
A
LEU
0.90
0.70
0.25
10
21
A
CYS
0.78
0.64
0.24
10
24
A
ALA
0.71
0.38
0.58
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.57
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.55
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.40
10
38
A
GLU
0.54
0.33
0.62
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.37
10
51
A
PHE
0.99
1.00
0.03
10
9
A
VAL
0.84
0.56
0.41
10
10
A
LEU
0.90
0.70
0.28
10
11
A
ASN
0.76
0.39
0.53
10
12
A
GLU
0.62
0.33
0.61
10
15
A
LEU
0.93
0.70
0.22
10
16
A
HIS
0.65
0.60
0.50
10
21
A
CYS
0.78
0.64
0.26
10
22
A
TYR
0.91
0.80
0.21
10
24
A
ALA
0.71
0.38
0.57
10
25
A
ASN
0.65
0.39
0.47
10
26
A
PRO
0.91
0.47
0.41
10
27
A
ARG
0.93
0.51
0.52
10
30
A
ALA
0.85
0.38
0.59
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.31
10
34
A
GLU
0.95
0.33
0.55
10
35
A
GLN
0.90
0.43
0.47
10
37
A
VAL
0.83
0.56
0.40
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.41
10
43
A
SER
0.74
0.36
0.51
10
44
A
PRO
0.92
0.47
0.44
10
45
A
ARG
0.92
0.51
0.54
10
48
A
ARG
0.86
0.51
0.41
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.05
10
61
A
ARG
0.57
0.51
0.28
10
63
A
ILE
0.70
0.64
0.43
10
64
A
MET
0.11
0.66
0.41
10
65
A
MET
0.13
0.66
0.61
10
66
A
LYS
0.04
0.25
0.67
10
9
A
VAL
0.84
0.56
0.43
10
10
A
LEU
0.90
0.70
0.26
10
12
A
GLU
0.62
0.33
0.59
10
16
A
HIS
0.65
0.60
0.46
10
19
A
ARG
0.93
0.51
0.44
10
22
A
TYR
0.91
0.80
0.22
10
23
A
ALA
0.77
0.38
0.52
10
24
A
ALA
0.71
0.38
0.57
10
25
A
ASN
0.65
0.39
0.47
10
26
A
PRO
0.91
0.47
0.41
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.62
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.31
10
35
A
GLN
0.90
0.43
0.48
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.45
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.35
10
45
A
ARG
0.92
0.51
0.51
10
48
A
ARG
0.86
0.51
0.43
10
50
A
TRP
1.00
0.99
0.00
10
51
A
PHE
0.99
1.00
0.06
10
21
A
CYS
0.78
0.64
0.27
10
22
A
TYR
0.91
0.80
0.28
10
23
A
ALA
0.77
0.38
0.57
10
24
A
ALA
0.71
0.38
0.61
10
27
A
ARG
0.93
0.51
0.55
10
30
A
ALA
0.85
0.38
0.55
10
31
A
LEU
0.68
0.70
0.59
10
32
A
MET
0.67
0.66
0.41
10
35
A
GLN
0.90
0.43
0.51
10
38
A
GLU
0.54
0.33
0.60
10
39
A
MET
0.72
0.66
0.42
10
41
A
GLY
0.83
0.41
0.54
10
42
A
LEU
0.97
0.70
0.36
10
51
A
PHE
0.99
1.00
0.05
10
1
A
MET
0.00
0.66
0.72
10
3
A
THR
0.61
0.33
0.49
10
5
A
ARG
0.83
0.51
0.49
10
7
A
ARG
0.94
0.51
0.47
10
9
A
VAL
0.84
0.56
0.51
10
10
A
LEU
0.90
0.70
0.27
10
11
A
ASN
0.76
0.39
0.51
10
12
A
GLU
0.62
0.33
0.57
10
16
A
HIS
0.65
0.60
0.44
10
21
A
CYS
0.78
0.64
0.19
10
22
A
TYR
0.91
0.80
0.19
10
24
A
ALA
0.71
0.38
0.49
10
26
A
PRO
0.91
0.47
0.41
10
27
A
ARG
0.93
0.51
0.57
10
30
A
ALA
0.85
0.38
0.58
10
31
A
LEU
0.68
0.70
0.60
10
32
A
MET
0.67
0.66
0.29
10
34
A
GLU
0.95
0.33
0.52
10
35
A
GLN
0.90
0.43
0.51
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.61
10
39
A
MET
0.72
0.66
0.44
10
41
A
GLY
0.83
0.41
0.57
10
42
A
LEU
0.97
0.70
0.39
10
45
A
ARG
0.92
0.51
0.41
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.09
10
55
A
ARG
0.95
0.51
0.52
10
63
A
ILE
0.70
0.64
0.34
10
64
A
MET
0.11
0.66
0.28
10
65
A
MET
0.13
0.66
0.47
10
66
A
LYS
0.04
0.25
0.66
10
22
A
TYR
0.91
0.80
0.27
10
23
A
ALA
0.77
0.38
0.54
10
24
A
ALA
0.71
0.38
0.55
10
25
A
ASN
0.65
0.39
0.46
10
26
A
PRO
0.91
0.47
0.46
10
27
A
ARG
0.93
0.51
0.53
10
30
A
ALA
0.85
0.38
0.56
10
31
A
LEU
0.68
0.70
0.61
10
32
A
MET
0.67
0.66
0.32
10
34
A
GLU
0.95
0.33
0.50
10
35
A
GLN
0.90
0.43
0.49
10
37
A
VAL
0.83
0.56
0.38
10
38
A
GLU
0.54
0.33
0.59
10
39
A
MET
0.72
0.66
0.41
10
41
A
GLY
0.83
0.41
0.48
10
42
A
LEU
0.97
0.70
0.29
10
45
A
ARG
0.92
0.51
0.44
10
48
A
ARG
0.86
0.51
0.39
10
50
A
TRP
1.00
0.99
0.02
10
51
A
PHE
0.99
1.00
0.07
10
52
A
GLN
0.92
0.43
0.41
10
55
A
ARG
0.95
0.51
0.51
10
56
A
CYS
0.83
0.64
0.47
10