Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1C55 chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.61
10
3
A
SER
0.29
0.36
0.60
10
4
A
THR
0.29
0.33
0.41
9
5
A
CYS
0.29
0.64
0.31
10
6
A
LEU
0.59
0.70
0.14
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.41
10
9
A
ALA
0.22
0.38
0.54
10
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.66
10
15
A
GLU
0.68
0.33
0.53
10
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.44
10
18
A
ASP
0.49
0.32
0.50
10
19
A
PRO
0.75
0.47
0.31
10
20
A
CYS
1.00
0.64
0.06
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.49
10
24
A
PHE
0.61
1.00
0.38
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.61
10
27
A
ALA
0.44
0.38
0.40
10
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.16
10
30
A
LYS
1.00
0.25
0.46
10
31
A
CYS
1.00
0.64
0.41
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.63
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.48
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.31
10
38
A
CYS
1.00
0.64
0.01
10
39
A
TYR
0.90
0.80
0.46
10
40
A
THR
0.47
0.33
0.61
10
1
A
TRP
0.29
0.99
0.76
10
2
A
CYS
0.29
0.64
0.62
10
3
A
SER
0.29
0.36
0.62
10
4
A
THR
0.29
0.33
0.45
4
5
A
CYS
0.29
0.64
0.35
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.59
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.57
7
10
A
CYS
1.00
0.64
0.43
10
11
A
GLY
0.29
0.41
0.63
10
12
A
ALA
0.49
0.38
0.64
10
13
A
SER
1.00
0.36
0.57
10
14
A
ARG
0.35
0.51
0.69
10
15
A
GLU
0.68
0.33
0.54
9
17
A
TYR
0.92
0.80
0.48
10
18
A
ASP
0.49
0.32
0.52
3
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.66
8
23
A
ALA
0.55
0.38
0.51
10
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.67
10
27
A
ALA
0.44
0.38
0.42
5
28
A
HIS
0.55
0.60
0.53
10
29
A
GLY
0.78
0.41
0.24
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.54
10
33
A
ASN
0.90
0.39
0.61
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.48
10
37
A
ARG
0.68
0.51
0.32
10
39
A
TYR
0.90
0.80
0.56
10
40
A
THR
0.47
0.33
0.67
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.60
10
5
A
CYS
0.29
0.64
0.35
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.57
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.55
4
10
A
CYS
1.00
0.64
0.40
10
11
A
GLY
0.29
0.41
0.59
10
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.55
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.51
2
17
A
TYR
0.92
0.80
0.46
10
19
A
PRO
0.75
0.47
0.27
10
21
A
PHE
0.31
1.00
0.54
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.44
8
24
A
PHE
0.61
1.00
0.43
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.43
3
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.17
10
30
A
LYS
1.00
0.25
0.46
10
31
A
CYS
1.00
0.64
0.40
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.50
10
37
A
ARG
0.68
0.51
0.27
10
38
A
CYS
1.00
0.64
0.08
10
39
A
TYR
0.90
0.80
0.49
10
40
A
THR
0.47
0.33
0.63
10
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.62
10
4
A
THR
0.29
0.33
0.46
7
5
A
CYS
0.29
0.64
0.31
10
6
A
LEU
0.59
0.70
0.12
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.51
6
10
A
CYS
1.00
0.64
0.39
10
11
A
GLY
0.29
0.41
0.58
10
12
A
ALA
0.49
0.38
0.57
10
13
A
SER
1.00
0.36
0.52
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.52
6
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.53
5
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.54
10
22
A
LYS
0.58
0.25
0.67
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.45
10
25
A
GLY
1.00
0.41
0.60
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.35
4
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.20
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.56
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.47
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.34
10
39
A
TYR
0.90
0.80
0.54
10
40
A
THR
0.47
0.33
0.66
10
1
A
TRP
0.29
0.99
0.71
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.61
10
4
A
THR
0.29
0.33
0.42
6
5
A
CYS
0.29
0.64
0.29
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.57
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.53
10
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.54
10
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.45
10
18
A
ASP
0.49
0.32
0.52
5
19
A
PRO
0.75
0.47
0.34
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.67
10
23
A
ALA
0.55
0.38
0.49
10
24
A
PHE
0.61
1.00
0.38
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.38
7
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.21
10
30
A
LYS
1.00
0.25
0.46
10
31
A
CYS
1.00
0.64
0.43
10
32
A
MET
0.70
0.66
0.48
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.49
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.25
10
39
A
TYR
0.90
0.80
0.48
10
40
A
THR
0.47
0.33
0.61
10
1
A
TRP
0.29
0.99
0.73
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.58
10
4
A
THR
0.29
0.33
0.41
2
5
A
CYS
0.29
0.64
0.33
9
6
A
LEU
0.59
0.70
0.19
10
7
A
ASP
0.85
0.32
0.59
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.49
7
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.61
9
12
A
ALA
0.49
0.38
0.61
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.54
10
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.46
10
18
A
ASP
0.49
0.32
0.52
7
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.52
10
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.43
9
28
A
HIS
0.55
0.60
0.49
10
29
A
GLY
0.78
0.41
0.27
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.42
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.64
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.48
9
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.32
10
39
A
TYR
0.90
0.80
0.54
10
40
A
THR
0.47
0.33
0.64
10
1
A
TRP
0.29
0.99
0.71
10
2
A
CYS
0.29
0.64
0.61
10
3
A
SER
0.29
0.36
0.58
10
5
A
CYS
0.29
0.64
0.33
10
6
A
LEU
0.59
0.70
0.11
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.45
10
9
A
ALA
0.22
0.38
0.55
4
10
A
CYS
1.00
0.64
0.43
10
11
A
GLY
0.29
0.41
0.60
8
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.54
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.53
5
16
A
CYS
1.00
0.64
0.14
10
17
A
TYR
0.92
0.80
0.44
10
18
A
ASP
0.49
0.32
0.50
1
19
A
PRO
0.75
0.47
0.27
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.62
8
23
A
ALA
0.55
0.38
0.47
4
24
A
PHE
0.61
1.00
0.37
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.60
10
27
A
ALA
0.44
0.38
0.36
5
28
A
HIS
0.55
0.60
0.45
10
29
A
GLY
0.78
0.41
0.17
10
30
A
LYS
1.00
0.25
0.48
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.47
10
33
A
ASN
0.90
0.39
0.62
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.48
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.30
10
39
A
TYR
0.90
0.80
0.52
10
40
A
THR
0.47
0.33
0.59
10
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.55
10
3
A
SER
0.29
0.36
0.59
9
4
A
THR
0.29
0.33
0.42
10
5
A
CYS
0.29
0.64
0.28
10
6
A
LEU
0.59
0.70
0.12
10
7
A
ASP
0.85
0.32
0.54
10
8
A
LEU
0.86
0.70
0.40
10
9
A
ALA
0.22
0.38
0.54
10
10
A
CYS
1.00
0.64
0.43
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.49
10
14
A
ARG
0.35
0.51
0.65
10
15
A
GLU
0.68
0.33
0.53
10
16
A
CYS
1.00
0.64
0.10
10
17
A
TYR
0.92
0.80
0.43
10
18
A
ASP
0.49
0.32
0.51
9
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.51
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.46
10
24
A
PHE
0.61
1.00
0.37
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.60
10
27
A
ALA
0.44
0.38
0.30
9
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.20
10
30
A
LYS
1.00
0.25
0.43
10
31
A
CYS
1.00
0.64
0.41
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.48
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.27
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.65
10
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.54
10
3
A
SER
0.29
0.36
0.57
10
5
A
CYS
0.29
0.64
0.29
10
6
A
LEU
0.59
0.70
0.14
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.40
10
9
A
ALA
0.22
0.38
0.51
8
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.60
9
13
A
SER
1.00
0.36
0.52
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.52
9
16
A
CYS
1.00
0.64
0.11
10
17
A
TYR
0.92
0.80
0.42
10
18
A
ASP
0.49
0.32
0.49
7
19
A
PRO
0.75
0.47
0.31
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.44
9
24
A
PHE
0.61
1.00
0.37
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.59
10
27
A
ALA
0.44
0.38
0.37
7
28
A
HIS
0.55
0.60
0.44
10
29
A
GLY
0.78
0.41
0.18
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.43
10
32
A
MET
0.70
0.66
0.48
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.47
9
37
A
ARG
0.68
0.51
0.27
10
39
A
TYR
0.90
0.80
0.49
10
40
A
THR
0.47
0.33
0.60
10
1
A
TRP
0.29
0.99
0.70
10
2
A
CYS
0.29
0.64
0.61
10
3
A
SER
0.29
0.36
0.63
10
4
A
THR
0.29
0.33
0.41
5
5
A
CYS
0.29
0.64
0.34
10
6
A
LEU
0.59
0.70
0.04
10
7
A
ASP
0.85
0.32
0.53
10
8
A
LEU
0.86
0.70
0.42
10
9
A
ALA
0.22
0.38
0.51
9
10
A
CYS
1.00
0.64
0.44
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.56
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.48
9
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.50
10
18
A
ASP
0.49
0.32
0.52
8
19
A
PRO
0.75
0.47
0.27
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.61
10
23
A
ALA
0.55
0.38
0.44
10
24
A
PHE
0.61
1.00
0.38
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.66
10
27
A
ALA
0.44
0.38
0.41
9
28
A
HIS
0.55
0.60
0.49
10
29
A
GLY
0.78
0.41
0.26
10
30
A
LYS
1.00
0.25
0.50
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.44
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.31
10
39
A
TYR
0.90
0.80
0.57
10
40
A
THR
0.47
0.33
0.66
10
1
A
TRP
0.29
0.99
0.63
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.63
10
4
A
THR
0.29
0.33
0.43
1
5
A
CYS
0.29
0.64
0.27
10
6
A
LEU
0.59
0.70
0.17
10
7
A
ASP
0.85
0.32
0.57
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.54
4
10
A
CYS
1.00
0.64
0.46
10
11
A
GLY
0.29
0.41
0.62
9
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.51
7
16
A
CYS
1.00
0.64
0.14
10
17
A
TYR
0.92
0.80
0.46
10
18
A
ASP
0.49
0.32
0.52
1
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.51
10
24
A
PHE
0.61
1.00
0.36
10
25
A
GLY
1.00
0.41
0.58
10
26
A
ARG
0.58
0.51
0.62
10
27
A
ALA
0.44
0.38
0.43
8
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.18
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.47
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.29
10
39
A
TYR
0.90
0.80
0.54
10
40
A
THR
0.47
0.33
0.63
10
1
A
TRP
0.29
0.99
0.75
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.56
10
5
A
CYS
0.29
0.64
0.34
10
6
A
LEU
0.59
0.70
0.10
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.45
10
9
A
ALA
0.22
0.38
0.52
10
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.56
10
14
A
ARG
0.35
0.51
0.70
10
15
A
GLU
0.68
0.33
0.54
9
16
A
CYS
1.00
0.64
0.17
10
17
A
TYR
0.92
0.80
0.48
10
18
A
ASP
0.49
0.32
0.51
8
19
A
PRO
0.75
0.47
0.29
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.61
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.36
10
25
A
GLY
1.00
0.41
0.58
10
26
A
ARG
0.58
0.51
0.61
10
27
A
ALA
0.44
0.38
0.39
9
28
A
HIS
0.55
0.60
0.47
10
29
A
GLY
0.78
0.41
0.25
10
30
A
LYS
1.00
0.25
0.51
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.60
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.48
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.29
10
39
A
TYR
0.90
0.80
0.54
10
40
A
THR
0.47
0.33
0.61
10
1
A
TRP
0.29
0.99
0.74
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.61
10
4
A
THR
0.29
0.33
0.38
8
5
A
CYS
0.29
0.64
0.39
10
6
A
LEU
0.59
0.70
0.22
10
7
A
ASP
0.85
0.32
0.62
10
8
A
LEU
0.86
0.70
0.48
10
9
A
ALA
0.22
0.38
0.56
10
10
A
CYS
1.00
0.64
0.41
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.61
10
13
A
SER
1.00
0.36
0.54
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.49
9
16
A
CYS
1.00
0.64
0.08
10
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.51
9
19
A
PRO
0.75
0.47
0.29
10
21
A
PHE
0.31
1.00
0.57
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.52
10
24
A
PHE
0.61
1.00
0.45
10
25
A
GLY
1.00
0.41
0.60
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.44
9
28
A
HIS
0.55
0.60
0.50
10
29
A
GLY
0.78
0.41
0.21
10
30
A
LYS
1.00
0.25
0.46
10
31
A
CYS
1.00
0.64
0.41
10
32
A
MET
0.70
0.66
0.47
10
33
A
ASN
0.90
0.39
0.61
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.50
9
37
A
ARG
0.68
0.51
0.29
10
39
A
TYR
0.90
0.80
0.53
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.57
10
4
A
THR
0.29
0.33
0.41
2
5
A
CYS
0.29
0.64
0.29
8
6
A
LEU
0.59
0.70
0.12
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.46
10
9
A
ALA
0.22
0.38
0.50
2
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.51
10
14
A
ARG
0.35
0.51
0.69
10
15
A
GLU
0.68
0.33
0.52
8
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.44
10
18
A
ASP
0.49
0.32
0.51
2
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.34
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.61
10
27
A
ALA
0.44
0.38
0.40
8
28
A
HIS
0.55
0.60
0.47
10
29
A
GLY
0.78
0.41
0.19
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.41
10
32
A
MET
0.70
0.66
0.49
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.46
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.25
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.71
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.60
10
4
A
THR
0.29
0.33
0.39
1
5
A
CYS
0.29
0.64
0.36
10
6
A
LEU
0.59
0.70
0.13
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.47
10
9
A
ALA
0.22
0.38
0.52
1
10
A
CYS
1.00
0.64
0.44
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.59
9
13
A
SER
1.00
0.36
0.56
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.52
8
16
A
CYS
1.00
0.64
0.13
10
17
A
TYR
0.92
0.80
0.43
10
18
A
ASP
0.49
0.32
0.50
1
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.45
3
24
A
PHE
0.61
1.00
0.40
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.35
4
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.24
10
30
A
LYS
1.00
0.25
0.48
10
31
A
CYS
1.00
0.64
0.42
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.62
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.47
7
37
A
ARG
0.68
0.51
0.27
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.61
10
1
A
TRP
0.29
0.99
0.73
10
2
A
CYS
0.29
0.64
0.57
10
3
A
SER
0.29
0.36
0.60
10
4
A
THR
0.29
0.33
0.45
7
5
A
CYS
0.29
0.64
0.28
9
6
A
LEU
0.59
0.70
0.21
10
7
A
ASP
0.85
0.32
0.60
10
8
A
LEU
0.86
0.70
0.47
10
9
A
ALA
0.22
0.38
0.54
9
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.64
10
12
A
ALA
0.49
0.38
0.62
10
13
A
SER
1.00
0.36
0.58
10
14
A
ARG
0.35
0.51
0.69
10
15
A
GLU
0.68
0.33
0.51
9
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.46
10
18
A
ASP
0.49
0.32
0.53
2
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.55
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.50
10
24
A
PHE
0.61
1.00
0.41
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.66
10
27
A
ALA
0.44
0.38
0.42
5
28
A
HIS
0.55
0.60
0.50
10
29
A
GLY
0.78
0.41
0.22
10
30
A
LYS
1.00
0.25
0.51
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.63
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.46
8
37
A
ARG
0.68
0.51
0.37
10
39
A
TYR
0.90
0.80
0.55
10
40
A
THR
0.47
0.33
0.66
10
1
A
TRP
0.29
0.99
0.73
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.58
10
4
A
THR
0.29
0.33
0.40
8
5
A
CYS
0.29
0.64
0.27
10
6
A
LEU
0.59
0.70
0.11
10
7
A
ASP
0.85
0.32
0.54
10
8
A
LEU
0.86
0.70
0.46
10
9
A
ALA
0.22
0.38
0.54
10
10
A
CYS
1.00
0.64
0.43
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.57
10
13
A
SER
1.00
0.36
0.49
10
14
A
ARG
0.35
0.51
0.64
10
15
A
GLU
0.68
0.33
0.48
10
16
A
CYS
1.00
0.64
0.08
10
17
A
TYR
0.92
0.80
0.41
10
18
A
ASP
0.49
0.32
0.52
9
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.44
10
24
A
PHE
0.61
1.00
0.36
10
25
A
GLY
1.00
0.41
0.52
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.34
8
28
A
HIS
0.55
0.60
0.45
10
29
A
GLY
0.78
0.41
0.18
10
30
A
LYS
1.00
0.25
0.43
10
31
A
CYS
1.00
0.64
0.42
10
32
A
MET
0.70
0.66
0.49
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.44
9
36
A
CYS
1.00
0.64
0.01
10
37
A
ARG
0.68
0.51
0.28
10
39
A
TYR
0.90
0.80
0.49
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.75
10
2
A
CYS
0.29
0.64
0.61
10
3
A
SER
0.29
0.36
0.56
10
4
A
THR
0.29
0.33
0.41
5
5
A
CYS
0.29
0.64
0.28
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.58
10
8
A
LEU
0.86
0.70
0.48
10
9
A
ALA
0.22
0.38
0.55
10
10
A
CYS
1.00
0.64
0.41
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.55
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.48
8
17
A
TYR
0.92
0.80
0.49
10
18
A
ASP
0.49
0.32
0.52
9
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.57
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.39
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.41
9
28
A
HIS
0.55
0.60
0.52
10
29
A
GLY
0.78
0.41
0.23
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.56
10
33
A
ASN
0.90
0.39
0.62
10
34
A
ASN
0.52
0.39
0.67
10
35
A
LYS
0.67
0.25
0.51
10
37
A
ARG
0.68
0.51
0.29
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.65
10
1
A
TRP
0.29
0.99
0.75
1
2
A
CYS
0.29
0.64
0.62
10
3
A
SER
0.29
0.36
0.56
10
4
A
THR
0.29
0.33
0.34
5
5
A
CYS
0.29
0.64
0.30
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.43
10
9
A
ALA
0.22
0.38
0.54
8
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.61
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.69
10
15
A
GLU
0.68
0.33
0.53
10
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.55
6
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.45
10
24
A
PHE
0.61
1.00
0.41
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.60
10
27
A
ALA
0.44
0.38
0.34
7
28
A
HIS
0.55
0.60
0.51
10
29
A
GLY
0.78
0.41
0.22
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.47
10
33
A
ASN
0.90
0.39
0.66
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.48
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.29
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.64
10
1
A
TRP
0.29
0.99
0.74
10
2
A
CYS
0.29
0.64
0.66
10
3
A
SER
0.29
0.36
0.64
10
4
A
THR
0.29
0.33
0.45
10
5
A
CYS
0.29
0.64
0.39
10
6
A
LEU
0.59
0.70
0.12
10
7
A
ASP
0.85
0.32
0.58
10
8
A
LEU
0.86
0.70
0.50
10
9
A
ALA
0.22
0.38
0.53
10
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.63
10
13
A
SER
1.00
0.36
0.58
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.51
7
16
A
CYS
1.00
0.64
0.14
10
17
A
TYR
0.92
0.80
0.49
10
18
A
ASP
0.49
0.32
0.53
10
19
A
PRO
0.75
0.47
0.29
10
21
A
PHE
0.31
1.00
0.54
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.47
10
24
A
PHE
0.61
1.00
0.46
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.40
9
28
A
HIS
0.55
0.60
0.54
10
29
A
GLY
0.78
0.41
0.26
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.46
10
32
A
MET
0.70
0.66
0.53
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.48
9
37
A
ARG
0.68
0.51
0.31
10
39
A
TYR
0.90
0.80
0.57
10
40
A
THR
0.47
0.33
0.66
10
1
A
TRP
0.29
0.99
0.74
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.58
10
4
A
THR
0.29
0.33
0.41
8
5
A
CYS
0.29
0.64
0.36
10
6
A
LEU
0.59
0.70
0.14
10
7
A
ASP
0.85
0.32
0.58
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.57
9
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.61
9
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.52
10
14
A
ARG
0.35
0.51
0.66
10
15
A
GLU
0.68
0.33
0.52
10
17
A
TYR
0.92
0.80
0.48
10
18
A
ASP
0.49
0.32
0.53
9
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.55
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.49
9
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.40
10
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.18
10
30
A
LYS
1.00
0.25
0.44
10
31
A
CYS
1.00
0.64
0.42
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.60
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.51
10
37
A
ARG
0.68
0.51
0.34
10
39
A
TYR
0.90
0.80
0.48
10
40
A
THR
0.47
0.33
0.59
10
1
A
TRP
0.29
0.99
0.75
9
2
A
CYS
0.29
0.64
0.63
10
3
A
SER
0.29
0.36
0.58
10
4
A
THR
0.29
0.33
0.43
6
5
A
CYS
0.29
0.64
0.31
8
6
A
LEU
0.59
0.70
0.13
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.43
10
9
A
ALA
0.22
0.38
0.55
9
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.50
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.54
8
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.53
8
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.63
10
23
A
ALA
0.55
0.38
0.41
10
24
A
PHE
0.61
1.00
0.40
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.66
10
27
A
ALA
0.44
0.38
0.42
9
28
A
HIS
0.55
0.60
0.51
10
29
A
GLY
0.78
0.41
0.26
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.47
9
37
A
ARG
0.68
0.51
0.34
10
38
A
CYS
1.00
0.64
0.08
10
39
A
TYR
0.90
0.80
0.48
10
40
A
THR
0.47
0.33
0.63
10
1
A
TRP
0.29
0.99
0.69
10
2
A
CYS
0.29
0.64
0.51
10
3
A
SER
0.29
0.36
0.63
10
4
A
THR
0.29
0.33
0.44
2
5
A
CYS
0.29
0.64
0.37
10
6
A
LEU
0.59
0.70
0.13
10
7
A
ASP
0.85
0.32
0.58
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.55
3
10
A
CYS
1.00
0.64
0.40
10
11
A
GLY
0.29
0.41
0.59
9
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.50
10
16
A
CYS
1.00
0.64
0.07
10
17
A
TYR
0.92
0.80
0.47
10
19
A
PRO
0.75
0.47
0.31
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.67
10
23
A
ALA
0.55
0.38
0.47
5
24
A
PHE
0.61
1.00
0.44
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.62
10
27
A
ALA
0.44
0.38
0.40
5
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.23
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.54
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.67
10
35
A
LYS
0.67
0.25
0.51
10
37
A
ARG
0.68
0.51
0.32
10
39
A
TYR
0.90
0.80
0.54
10
40
A
THR
0.47
0.33
0.65
9
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.58
10
3
A
SER
0.29
0.36
0.64
10
4
A
THR
0.29
0.33
0.44
9
5
A
CYS
0.29
0.64
0.34
10
6
A
LEU
0.59
0.70
0.20
10
7
A
ASP
0.85
0.32
0.61
10
8
A
LEU
0.86
0.70
0.53
10
9
A
ALA
0.22
0.38
0.54
9
10
A
CYS
1.00
0.64
0.40
10
11
A
GLY
0.29
0.41
0.58
9
12
A
ALA
0.49
0.38
0.61
10
13
A
SER
1.00
0.36
0.55
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.52
4
16
A
CYS
1.00
0.64
0.12
10
17
A
TYR
0.92
0.80
0.49
10
18
A
ASP
0.49
0.32
0.53
8
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.67
10
23
A
ALA
0.55
0.38
0.52
9
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.61
10
27
A
ALA
0.44
0.38
0.41
5
28
A
HIS
0.55
0.60
0.50
10
29
A
GLY
0.78
0.41
0.21
10
30
A
LYS
1.00
0.25
0.45
10
31
A
CYS
1.00
0.64
0.43
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.64
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.51
6
37
A
ARG
0.68
0.51
0.28
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.64
10
1
A
TRP
0.29
0.99
0.68
10
2
A
CYS
0.29
0.64
0.58
10
3
A
SER
0.29
0.36
0.61
10
4
A
THR
0.29
0.33
0.44
8
5
A
CYS
0.29
0.64
0.32
10
6
A
LEU
0.59
0.70
0.17
10
7
A
ASP
0.85
0.32
0.60
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.55
8
10
A
CYS
1.00
0.64
0.45
10
11
A
GLY
0.29
0.41
0.62
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.48
10
14
A
ARG
0.35
0.51
0.63
10
15
A
GLU
0.68
0.33
0.51
10
16
A
CYS
1.00
0.64
0.08
10
17
A
TYR
0.92
0.80
0.45
10
18
A
ASP
0.49
0.32
0.53
7
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.57
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.50
9
24
A
PHE
0.61
1.00
0.41
10
25
A
GLY
1.00
0.41
0.58
10
26
A
ARG
0.58
0.51
0.62
10
27
A
ALA
0.44
0.38
0.36
5
28
A
HIS
0.55
0.60
0.45
10
29
A
GLY
0.78
0.41
0.17
10
30
A
LYS
1.00
0.25
0.45
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.67
10
35
A
LYS
0.67
0.25
0.48
6
37
A
ARG
0.68
0.51
0.31
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.72
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.59
9
4
A
THR
0.29
0.33
0.40
7
5
A
CYS
0.29
0.64
0.28
10
6
A
LEU
0.59
0.70
0.19
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.46
10
9
A
ALA
0.22
0.38
0.56
10
10
A
CYS
1.00
0.64
0.46
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.46
10
14
A
ARG
0.35
0.51
0.66
10
15
A
GLU
0.68
0.33
0.54
8
16
A
CYS
1.00
0.64
0.16
10
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.54
8
19
A
PRO
0.75
0.47
0.36
10
21
A
PHE
0.31
1.00
0.56
10
22
A
LYS
0.58
0.25
0.69
10
23
A
ALA
0.55
0.38
0.44
10
24
A
PHE
0.61
1.00
0.38
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.60
10
27
A
ALA
0.44
0.38
0.39
7
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.15
10
30
A
LYS
1.00
0.25
0.46
10
31
A
CYS
1.00
0.64
0.45
10
32
A
MET
0.70
0.66
0.48
10
33
A
ASN
0.90
0.39
0.62
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.50
10
36
A
CYS
1.00
0.64
0.02
10
37
A
ARG
0.68
0.51
0.28
10
39
A
TYR
0.90
0.80
0.47
10
40
A
THR
0.47
0.33
0.60
10
1
A
TRP
0.29
0.99
0.71
10
2
A
CYS
0.29
0.64
0.55
10
3
A
SER
0.29
0.36
0.61
10
4
A
THR
0.29
0.33
0.46
6
5
A
CYS
0.29
0.64
0.24
9
6
A
LEU
0.59
0.70
0.16
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.45
10
9
A
ALA
0.22
0.38
0.52
8
10
A
CYS
1.00
0.64
0.41
10
11
A
GLY
0.29
0.41
0.59
10
12
A
ALA
0.49
0.38
0.60
10
13
A
SER
1.00
0.36
0.50
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.53
8
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.44
10
18
A
ASP
0.49
0.32
0.51
6
19
A
PRO
0.75
0.47
0.32
10
20
A
CYS
1.00
0.64
0.05
10
21
A
PHE
0.31
1.00
0.50
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.45
10
24
A
PHE
0.61
1.00
0.40
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.34
6
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.28
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.37
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.47
9
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.30
10
39
A
TYR
0.90
0.80
0.50
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.72
9
2
A
CYS
0.29
0.64
0.57
9
3
A
SER
0.29
0.36
0.57
10
4
A
THR
0.29
0.33
0.42
8
5
A
CYS
0.29
0.64
0.27
10
6
A
LEU
0.59
0.70
0.10
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.42
10
9
A
ALA
0.22
0.38
0.52
10
10
A
CYS
1.00
0.64
0.41
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.53
10
14
A
ARG
0.35
0.51
0.66
10
15
A
GLU
0.68
0.33
0.49
9
16
A
CYS
1.00
0.64
0.11
10
17
A
TYR
0.92
0.80
0.45
10
18
A
ASP
0.49
0.32
0.52
8
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.52
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.61
10
27
A
ALA
0.44
0.38
0.35
9
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.23
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.43
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.67
10
34
A
ASN
0.52
0.39
0.63
10
35
A
LYS
0.67
0.25
0.47
9
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.31
10
38
A
CYS
1.00
0.64
0.05
10
39
A
TYR
0.90
0.80
0.51
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.73
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.60
10
4
A
THR
0.29
0.33
0.41
2
5
A
CYS
0.29
0.64
0.30
9
6
A
LEU
0.59
0.70
0.07
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.49
4
10
A
CYS
1.00
0.64
0.44
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.57
10
14
A
ARG
0.35
0.51
0.70
10
15
A
GLU
0.68
0.33
0.50
8
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.45
10
18
A
ASP
0.49
0.32
0.50
2
19
A
PRO
0.75
0.47
0.28
10
21
A
PHE
0.31
1.00
0.53
10
22
A
LYS
0.58
0.25
0.64
10
23
A
ALA
0.55
0.38
0.42
7
24
A
PHE
0.61
1.00
0.35
10
25
A
GLY
1.00
0.41
0.57
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.35
4
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.18
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.51
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.47
9
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.31
10
39
A
TYR
0.90
0.80
0.50
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.76
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.59
10
5
A
CYS
0.29
0.64
0.31
5
6
A
LEU
0.59
0.70
0.16
10
7
A
ASP
0.85
0.32
0.57
10
8
A
LEU
0.86
0.70
0.47
10
9
A
ALA
0.22
0.38
0.56
4
10
A
CYS
1.00
0.64
0.44
10
11
A
GLY
0.29
0.41
0.62
7
12
A
ALA
0.49
0.38
0.61
5
13
A
SER
1.00
0.36
0.55
10
14
A
ARG
0.35
0.51
0.68
10
15
A
GLU
0.68
0.33
0.51
9
16
A
CYS
1.00
0.64
0.13
10
17
A
TYR
0.92
0.80
0.46
10
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.54
10
22
A
LYS
0.58
0.25
0.69
10
23
A
ALA
0.55
0.38
0.46
5
24
A
PHE
0.61
1.00
0.41
10
25
A
GLY
1.00
0.41
0.59
10
26
A
ARG
0.58
0.51
0.64
10
27
A
ALA
0.44
0.38
0.41
3
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.24
10
30
A
LYS
1.00
0.25
0.50
10
31
A
CYS
1.00
0.64
0.43
10
32
A
MET
0.70
0.66
0.50
10
33
A
ASN
0.90
0.39
0.64
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.46
8
37
A
ARG
0.68
0.51
0.33
10
39
A
TYR
0.90
0.80
0.56
10
40
A
THR
0.47
0.33
0.65
10
1
A
TRP
0.29
0.99
0.76
10
2
A
CYS
0.29
0.64
0.62
10
3
A
SER
0.29
0.36
0.58
10
4
A
THR
0.29
0.33
0.46
2
5
A
CYS
0.29
0.64
0.30
5
6
A
LEU
0.59
0.70
0.25
10
7
A
ASP
0.85
0.32
0.60
10
8
A
LEU
0.86
0.70
0.49
10
9
A
ALA
0.22
0.38
0.57
6
10
A
CYS
1.00
0.64
0.40
10
11
A
GLY
0.29
0.41
0.61
8
12
A
ALA
0.49
0.38
0.61
10
13
A
SER
1.00
0.36
0.54
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.52
5
17
A
TYR
0.92
0.80
0.47
10
19
A
PRO
0.75
0.47
0.33
10
21
A
PHE
0.31
1.00
0.57
10
22
A
LYS
0.58
0.25
0.67
10
23
A
ALA
0.55
0.38
0.48
7
24
A
PHE
0.61
1.00
0.44
10
25
A
GLY
1.00
0.41
0.60
10
26
A
ARG
0.58
0.51
0.65
10
27
A
ALA
0.44
0.38
0.45
5
28
A
HIS
0.55
0.60
0.52
10
29
A
GLY
0.78
0.41
0.23
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.52
10
33
A
ASN
0.90
0.39
0.62
10
34
A
ASN
0.52
0.39
0.66
10
35
A
LYS
0.67
0.25
0.49
10
37
A
ARG
0.68
0.51
0.35
10
39
A
TYR
0.90
0.80
0.52
10
40
A
THR
0.47
0.33
0.66
10
1
A
TRP
0.29
0.99
0.75
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.53
10
4
A
THR
0.29
0.33
0.36
6
5
A
CYS
0.29
0.64
0.27
9
6
A
LEU
0.59
0.70
0.14
10
7
A
ASP
0.85
0.32
0.55
10
8
A
LEU
0.86
0.70
0.45
10
9
A
ALA
0.22
0.38
0.53
9
10
A
CYS
1.00
0.64
0.46
10
11
A
GLY
0.29
0.41
0.61
10
12
A
ALA
0.49
0.38
0.59
10
13
A
SER
1.00
0.36
0.52
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.51
10
16
A
CYS
1.00
0.64
0.11
10
17
A
TYR
0.92
0.80
0.44
10
18
A
ASP
0.49
0.32
0.49
8
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.54
10
22
A
LYS
0.58
0.25
0.65
10
23
A
ALA
0.55
0.38
0.48
10
24
A
PHE
0.61
1.00
0.39
10
25
A
GLY
1.00
0.41
0.55
10
26
A
ARG
0.58
0.51
0.63
10
27
A
ALA
0.44
0.38
0.38
9
28
A
HIS
0.55
0.60
0.47
10
29
A
GLY
0.78
0.41
0.19
10
30
A
LYS
1.00
0.25
0.49
10
31
A
CYS
1.00
0.64
0.46
10
32
A
MET
0.70
0.66
0.49
10
33
A
ASN
0.90
0.39
0.60
10
34
A
ASN
0.52
0.39
0.64
10
35
A
LYS
0.67
0.25
0.46
10
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.31
10
39
A
TYR
0.90
0.80
0.55
10
40
A
THR
0.47
0.33
0.62
10
1
A
TRP
0.29
0.99
0.66
10
2
A
CYS
0.29
0.64
0.59
10
3
A
SER
0.29
0.36
0.62
10
4
A
THR
0.29
0.33
0.44
2
5
A
CYS
0.29
0.64
0.32
10
6
A
LEU
0.59
0.70
0.18
10
7
A
ASP
0.85
0.32
0.58
10
8
A
LEU
0.86
0.70
0.44
10
9
A
ALA
0.22
0.38
0.52
2
10
A
CYS
1.00
0.64
0.44
10
11
A
GLY
0.29
0.41
0.61
8
12
A
ALA
0.49
0.38
0.60
5
13
A
SER
1.00
0.36
0.54
10
14
A
ARG
0.35
0.51
0.67
10
15
A
GLU
0.68
0.33
0.53
7
16
A
CYS
1.00
0.64
0.14
10
17
A
TYR
0.92
0.80
0.43
10
18
A
ASP
0.49
0.32
0.49
1
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.51
10
22
A
LYS
0.58
0.25
0.63
10
23
A
ALA
0.55
0.38
0.46
4
24
A
PHE
0.61
1.00
0.42
10
25
A
GLY
1.00
0.41
0.56
10
26
A
ARG
0.58
0.51
0.66
10
27
A
ALA
0.44
0.38
0.35
4
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.22
10
30
A
LYS
1.00
0.25
0.47
10
31
A
CYS
1.00
0.64
0.44
10
32
A
MET
0.70
0.66
0.54
10
33
A
ASN
0.90
0.39
0.65
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.47
7
37
A
ARG
0.68
0.51
0.33
10
39
A
TYR
0.90
0.80
0.48
10
40
A
THR
0.47
0.33
0.63
8
1
A
TRP
0.29
0.99
0.68
10
2
A
CYS
0.29
0.64
0.62
10
3
A
SER
0.29
0.36
0.59
10
4
A
THR
0.29
0.33
0.41
2
5
A
CYS
0.29
0.64
0.30
10
6
A
LEU
0.59
0.70
0.13
10
7
A
ASP
0.85
0.32
0.56
10
8
A
LEU
0.86
0.70
0.43
10
9
A
ALA
0.22
0.38
0.52
4
10
A
CYS
1.00
0.64
0.43
10
11
A
GLY
0.29
0.41
0.60
10
12
A
ALA
0.49
0.38
0.58
10
13
A
SER
1.00
0.36
0.55
10
14
A
ARG
0.35
0.51
0.69
10
15
A
GLU
0.68
0.33
0.49
9
16
A
CYS
1.00
0.64
0.15
10
17
A
TYR
0.92
0.80
0.47
10
18
A
ASP
0.49
0.32
0.52
2
19
A
PRO
0.75
0.47
0.32
10
21
A
PHE
0.31
1.00
0.51
10
22
A
LYS
0.58
0.25
0.62
10
23
A
ALA
0.55
0.38
0.47
10
24
A
PHE
0.61
1.00
0.38
10
25
A
GLY
1.00
0.41
0.54
10
26
A
ARG
0.58
0.51
0.64
10
27
A
ALA
0.44
0.38
0.39
7
28
A
HIS
0.55
0.60
0.46
10
29
A
GLY
0.78
0.41
0.21
10
30
A
LYS
1.00
0.25
0.48
10
31
A
CYS
1.00
0.64
0.46
10
32
A
MET
0.70
0.66
0.48
10
33
A
ASN
0.90
0.39
0.67
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.49
9
36
A
CYS
1.00
0.64
0.00
10
37
A
ARG
0.68
0.51
0.30
10
39
A
TYR
0.90
0.80
0.52
10
40
A
THR
0.47
0.33
0.63
10
1
A
TRP
0.29
0.99
0.74
10
2
A
CYS
0.29
0.64
0.60
10
3
A
SER
0.29
0.36
0.61
10
4
A
THR
0.29
0.33
0.44
1
5
A
CYS
0.29
0.64
0.33
3
6
A
LEU
0.59
0.70
0.17
10
7
A
ASP
0.85
0.32
0.57
10
8
A
LEU
0.86
0.70
0.47
10
9
A
ALA
0.22
0.38
0.52
1
10
A
CYS
1.00
0.64
0.42
10
11
A
GLY
0.29
0.41
0.61
8
12
A
ALA
0.49
0.38
0.63
10
13
A
SER
1.00
0.36
0.57
10
14
A
ARG
0.35
0.51
0.70
10
15
A
GLU
0.68
0.33
0.50
8
16
A
CYS
1.00
0.64
0.13
10
17
A
TYR
0.92
0.80
0.47
10
19
A
PRO
0.75
0.47
0.30
10
21
A
PHE
0.31
1.00
0.55
10
22
A
LYS
0.58
0.25
0.66
10
23
A
ALA
0.55
0.38
0.46
3
24
A
PHE
0.61
1.00
0.43
10
25
A
GLY
1.00
0.41
0.58
10
26
A
ARG
0.58
0.51
0.64
10
27
A
ALA
0.44
0.38
0.40
2
28
A
HIS
0.55
0.60
0.48
10
29
A
GLY
0.78
0.41
0.23
10
30
A
LYS
1.00
0.25
0.50
10
31
A
CYS
1.00
0.64
0.47
10
32
A
MET
0.70
0.66
0.54
10
33
A
ASN
0.90
0.39
0.64
10
34
A
ASN
0.52
0.39
0.65
10
35
A
LYS
0.67
0.25
0.47
8
37
A
ARG
0.68
0.51
0.37
10
39
A
TYR
0.90
0.80
0.56
10
40
A
THR
0.47
0.33
0.63
10