Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1D1R chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
30
A
GLY
0.44
0.41
0.77
6
31
A
ASP
0.57
0.32
0.77
5
32
A
GLY
0.76
0.41
0.62
9
33
A
VAL
0.31
0.56
0.55
9
34
A
VAL
0.67
0.56
0.21
1
35
A
ARG
0.64
0.51
0.39
9
39
A
GLN
0.57
0.43
0.60
10
41
A
SER
0.60
0.36
0.77
10
42
A
GLY
0.81
0.41
0.78
8
43
A
ARG
0.86
0.51
0.85
9
44
A
LYS
0.67
0.25
0.80
10
45
A
GLY
0.87
0.41
0.80
10
46
A
LYS
0.88
0.25
0.74
10
48
A
VAL
0.81
0.56
0.51
10
49
A
CYS
0.90
0.64
0.24
10
50
A
LEU
0.57
0.70
0.36
10
51
A
ILE
0.65
0.64
0.00
9
53
A
GLY
0.93
0.41
0.45
9
54
A
VAL
0.77
0.56
0.33
9
55
A
ASP
0.63
0.32
0.63
9
56
A
LEU
0.64
0.70
0.60
9
57
A
ASP
0.38
0.32
0.76
9
58
A
ASP
0.38
0.32
0.74
9
59
A
ALA
0.38
0.38
0.77
9
60
A
GLU
0.73
0.33
0.66
9
61
A
LEU
0.75
0.70
0.49
9
64
A
LEU
0.77
0.70
0.38
10
66
A
ALA
0.74
0.38
0.58
1
68
A
LEU
0.87
0.70
0.28
10
69
A
LYS
0.89
0.25
0.60
10
70
A
LYS
0.51
0.25
0.73
10
71
A
LYS
0.57
0.25
0.70
10
72
A
CYS
0.77
0.64
0.53
10
73
A
GLY
0.85
0.41
0.66
10
74
A
CYS
0.71
0.64
0.65
10
75
A
GLY
0.96
0.41
0.65
10
76
A
GLY
0.96
0.41
0.52
10
77
A
ALA
0.84
0.38
0.59
10
78
A
VAL
0.65
0.56
0.54
10
79
A
LYS
0.82
0.25
0.68
10
80
A
ASP
0.58
0.32
0.71
10
81
A
GLY
0.67
0.41
0.54
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.48
10
85
A
ILE
0.80
0.64
0.27
10
86
A
GLN
1.00
0.43
0.57
10
87
A
GLY
0.95
0.41
0.45
10
88
A
ASP
0.78
0.32
0.51
7
89
A
LYS
0.79
0.25
0.52
2
90
A
ARG
0.64
0.51
0.41
10
91
A
ASP
0.51
0.32
0.55
10
92
A
LEU
0.67
0.70
0.51
10
93
A
LEU
0.61
0.70
0.14
10
95
A
SER
0.39
0.36
0.55
9
96
A
LEU
0.42
0.70
0.33
10
98
A
GLU
0.44
0.33
0.62
8
101
A
GLY
0.84
0.41
0.68
6
102
A
MET
0.71
0.66
0.54
9
103
A
LYS
0.36
0.25
0.67
6
104
A
VAL
0.53
0.56
0.45
8
105
A
LYS
0.65
0.25
0.57
1
106
A
LEU
0.43
0.70
0.50
8
107
A
ALA
0.44
0.38
0.50
2
108
A
GLY
0.69
0.41
0.64
2
109
A
GLY
0.66
0.41
0.73
2
31
A
ASP
0.57
0.32
0.72
7
32
A
GLY
0.76
0.41
0.58
1
33
A
VAL
0.31
0.56
0.53
8
35
A
ARG
0.64
0.51
0.40
8
38
A
ARG
0.56
0.51
0.52
4
39
A
GLN
0.57
0.43
0.59
10
41
A
SER
0.60
0.36
0.78
10
42
A
GLY
0.81
0.41
0.81
10
43
A
ARG
0.86
0.51
0.88
10
45
A
GLY
0.87
0.41
0.79
10
46
A
LYS
0.88
0.25
0.78
8
48
A
VAL
0.81
0.56
0.51
10
50
A
LEU
0.57
0.70
0.35
10
53
A
GLY
0.93
0.41
0.46
8
54
A
VAL
0.77
0.56
0.36
8
55
A
ASP
0.63
0.32
0.62
4
56
A
LEU
0.64
0.70
0.60
8
57
A
ASP
0.38
0.32
0.77
8
58
A
ASP
0.38
0.32
0.74
8
59
A
ALA
0.38
0.38
0.77
8
60
A
GLU
0.73
0.33
0.68
8
61
A
LEU
0.75
0.70
0.50
8
63
A
LYS
0.37
0.25
0.70
3
64
A
LEU
0.77
0.70
0.39
10
66
A
ALA
0.74
0.38
0.59
4
68
A
LEU
0.87
0.70
0.26
10
69
A
LYS
0.89
0.25
0.58
10
70
A
LYS
0.51
0.25
0.71
7
71
A
LYS
0.57
0.25
0.65
5
72
A
CYS
0.77
0.64
0.48
10
73
A
GLY
0.85
0.41
0.67
10
74
A
CYS
0.71
0.64
0.60
10
75
A
GLY
0.96
0.41
0.65
10
76
A
GLY
0.96
0.41
0.61
10
77
A
ALA
0.84
0.38
0.59
10
78
A
VAL
0.65
0.56
0.52
10
79
A
LYS
0.82
0.25
0.68
10
80
A
ASP
0.58
0.32
0.67
10
81
A
GLY
0.67
0.41
0.56
10
82
A
VAL
0.60
0.56
0.51
10
84
A
GLU
0.83
0.33
0.41
10
86
A
GLN
1.00
0.43
0.58
10
87
A
GLY
0.95
0.41
0.52
10
88
A
ASP
0.78
0.32
0.56
10
89
A
LYS
0.79
0.25
0.55
4
90
A
ARG
0.64
0.51
0.43
10
91
A
ASP
0.51
0.32
0.57
4
92
A
LEU
0.67
0.70
0.53
5
95
A
SER
0.39
0.36
0.56
2
96
A
LEU
0.42
0.70
0.35
10
98
A
GLU
0.44
0.33
0.61
8
99
A
ALA
0.42
0.38
0.63
1
101
A
GLY
0.84
0.41
0.66
7
102
A
MET
0.71
0.66
0.50
8
103
A
LYS
0.36
0.25
0.67
1
104
A
VAL
0.53
0.56
0.39
6
31
A
ASP
0.57
0.32
0.73
9
33
A
VAL
0.31
0.56
0.47
10
35
A
ARG
0.64
0.51
0.38
10
38
A
ARG
0.56
0.51
0.55
10
39
A
GLN
0.57
0.43
0.55
10
41
A
SER
0.60
0.36
0.73
10
42
A
GLY
0.81
0.41
0.80
10
43
A
ARG
0.86
0.51
0.87
10
44
A
LYS
0.67
0.25
0.80
10
45
A
GLY
0.87
0.41
0.75
10
46
A
LYS
0.88
0.25
0.78
10
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.34
10
53
A
GLY
0.93
0.41
0.33
3
54
A
VAL
0.77
0.56
0.31
10
56
A
LEU
0.64
0.70
0.57
10
57
A
ASP
0.38
0.32
0.77
10
58
A
ASP
0.38
0.32
0.74
10
59
A
ALA
0.38
0.38
0.77
10
60
A
GLU
0.73
0.33
0.69
10
61
A
LEU
0.75
0.70
0.49
10
63
A
LYS
0.37
0.25
0.71
10
64
A
LEU
0.77
0.70
0.38
10
66
A
ALA
0.74
0.38
0.60
8
68
A
LEU
0.87
0.70
0.29
10
69
A
LYS
0.89
0.25
0.60
10
70
A
LYS
0.51
0.25
0.71
10
71
A
LYS
0.57
0.25
0.70
10
72
A
CYS
0.77
0.64
0.56
10
73
A
GLY
0.85
0.41
0.70
10
74
A
CYS
0.71
0.64
0.65
10
75
A
GLY
0.96
0.41
0.61
10
76
A
GLY
0.96
0.41
0.60
10
77
A
ALA
0.84
0.38
0.59
10
78
A
VAL
0.65
0.56
0.52
10
79
A
LYS
0.82
0.25
0.69
10
80
A
ASP
0.58
0.32
0.70
10
81
A
GLY
0.67
0.41
0.58
10
82
A
VAL
0.60
0.56
0.50
10
84
A
GLU
0.83
0.33
0.40
10
85
A
ILE
0.80
0.64
0.28
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.48
10
88
A
ASP
0.78
0.32
0.52
10
89
A
LYS
0.79
0.25
0.59
2
90
A
ARG
0.64
0.51
0.53
10
91
A
ASP
0.51
0.32
0.62
10
92
A
LEU
0.67
0.70
0.55
10
93
A
LEU
0.61
0.70
0.24
10
94
A
LYS
0.51
0.25
0.59
10
95
A
SER
0.39
0.36
0.64
10
96
A
LEU
0.42
0.70
0.39
10
98
A
GLU
0.44
0.33
0.65
10
100
A
LYS
0.51
0.25
0.60
10
101
A
GLY
0.84
0.41
0.69
6
102
A
MET
0.71
0.66
0.53
10
103
A
LYS
0.36
0.25
0.64
6
104
A
VAL
0.53
0.56
0.40
10
106
A
LEU
0.43
0.70
0.50
5
31
A
ASP
0.57
0.32
0.73
7
32
A
GLY
0.76
0.41
0.59
10
33
A
VAL
0.31
0.56
0.49
10
35
A
ARG
0.64
0.51
0.39
10
41
A
SER
0.60
0.36
0.74
9
42
A
GLY
0.81
0.41
0.79
9
43
A
ARG
0.86
0.51
0.86
9
44
A
LYS
0.67
0.25
0.82
9
45
A
GLY
0.87
0.41
0.77
9
46
A
LYS
0.88
0.25
0.74
9
48
A
VAL
0.81
0.56
0.48
10
50
A
LEU
0.57
0.70
0.35
10
51
A
ILE
0.65
0.64
0.00
10
53
A
GLY
0.93
0.41
0.46
10
54
A
VAL
0.77
0.56
0.37
10
55
A
ASP
0.63
0.32
0.64
10
56
A
LEU
0.64
0.70
0.60
10
57
A
ASP
0.38
0.32
0.76
10
58
A
ASP
0.38
0.32
0.76
10
59
A
ALA
0.38
0.38
0.76
10
60
A
GLU
0.73
0.33
0.65
10
61
A
LEU
0.75
0.70
0.49
10
64
A
LEU
0.77
0.70
0.36
10
66
A
ALA
0.74
0.38
0.61
4
68
A
LEU
0.87
0.70
0.34
10
69
A
LYS
0.89
0.25
0.59
10
70
A
LYS
0.51
0.25
0.70
10
71
A
LYS
0.57
0.25
0.67
10
72
A
CYS
0.77
0.64
0.49
10
73
A
GLY
0.85
0.41
0.66
10
74
A
CYS
0.71
0.64
0.66
10
75
A
GLY
0.96
0.41
0.58
10
76
A
GLY
0.96
0.41
0.61
10
77
A
ALA
0.84
0.38
0.62
10
78
A
VAL
0.65
0.56
0.56
10
79
A
LYS
0.82
0.25
0.69
10
80
A
ASP
0.58
0.32
0.68
10
81
A
GLY
0.67
0.41
0.55
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.47
10
85
A
ILE
0.80
0.64
0.27
10
86
A
GLN
1.00
0.43
0.56
10
87
A
GLY
0.95
0.41
0.47
10
88
A
ASP
0.78
0.32
0.51
10
90
A
ARG
0.64
0.51
0.47
10
91
A
ASP
0.51
0.32
0.57
10
92
A
LEU
0.67
0.70
0.52
10
93
A
LEU
0.61
0.70
0.16
10
95
A
SER
0.39
0.36
0.58
10
96
A
LEU
0.42
0.70
0.38
10
98
A
GLU
0.44
0.33
0.63
10
99
A
ALA
0.42
0.38
0.65
6
101
A
GLY
0.84
0.41
0.68
6
102
A
MET
0.71
0.66
0.51
10
104
A
VAL
0.53
0.56
0.41
5
31
A
ASP
0.57
0.32
0.73
8
33
A
VAL
0.31
0.56
0.49
9
35
A
ARG
0.64
0.51
0.39
9
39
A
GLN
0.57
0.43
0.55
10
41
A
SER
0.60
0.36
0.71
4
42
A
GLY
0.81
0.41
0.78
10
43
A
ARG
0.86
0.51
0.86
10
44
A
LYS
0.67
0.25
0.86
10
45
A
GLY
0.87
0.41
0.76
10
46
A
LYS
0.88
0.25
0.72
10
47
A
GLY
0.57
0.41
0.55
1
48
A
VAL
0.81
0.56
0.46
10
50
A
LEU
0.57
0.70
0.36
10
52
A
THR
0.53
0.33
0.42
3
53
A
GLY
0.93
0.41
0.38
8
54
A
VAL
0.77
0.56
0.31
9
56
A
LEU
0.64
0.70
0.59
9
57
A
ASP
0.38
0.32
0.73
9
58
A
ASP
0.38
0.32
0.73
9
59
A
ALA
0.38
0.38
0.76
9
60
A
GLU
0.73
0.33
0.66
9
61
A
LEU
0.75
0.70
0.46
10
63
A
LYS
0.37
0.25
0.70
4
64
A
LEU
0.77
0.70
0.36
10
66
A
ALA
0.74
0.38
0.56
5
68
A
LEU
0.87
0.70
0.22
10
69
A
LYS
0.89
0.25
0.55
10
70
A
LYS
0.51
0.25
0.68
9
71
A
LYS
0.57
0.25
0.65
10
72
A
CYS
0.77
0.64
0.47
10
73
A
GLY
0.85
0.41
0.66
10
74
A
CYS
0.71
0.64
0.63
10
75
A
GLY
0.96
0.41
0.53
10
76
A
GLY
0.96
0.41
0.57
10
77
A
ALA
0.84
0.38
0.56
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.66
10
80
A
ASP
0.58
0.32
0.64
10
81
A
GLY
0.67
0.41
0.54
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.41
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.44
10
88
A
ASP
0.78
0.32
0.51
10
89
A
LYS
0.79
0.25
0.52
4
90
A
ARG
0.64
0.51
0.52
10
91
A
ASP
0.51
0.32
0.58
9
92
A
LEU
0.67
0.70
0.51
9
94
A
LYS
0.51
0.25
0.56
7
95
A
SER
0.39
0.36
0.57
9
96
A
LEU
0.42
0.70
0.31
9
98
A
GLU
0.44
0.33
0.64
8
99
A
ALA
0.42
0.38
0.63
1
101
A
GLY
0.84
0.41
0.70
8
102
A
MET
0.71
0.66
0.53
9
103
A
LYS
0.36
0.25
0.69
8
104
A
VAL
0.53
0.56
0.44
8
31
A
ASP
0.57
0.32
0.77
6
33
A
VAL
0.31
0.56
0.54
9
35
A
ARG
0.64
0.51
0.39
9
41
A
SER
0.60
0.36
0.71
10
42
A
GLY
0.81
0.41
0.74
10
43
A
ARG
0.86
0.51
0.86
10
44
A
LYS
0.67
0.25
0.80
10
45
A
GLY
0.87
0.41
0.71
10
46
A
LYS
0.88
0.25
0.78
10
48
A
VAL
0.81
0.56
0.47
10
49
A
CYS
0.90
0.64
0.20
10
50
A
LEU
0.57
0.70
0.29
10
54
A
VAL
0.77
0.56
0.31
9
55
A
ASP
0.63
0.32
0.60
9
56
A
LEU
0.64
0.70
0.62
9
57
A
ASP
0.38
0.32
0.75
9
58
A
ASP
0.38
0.32
0.74
9
59
A
ALA
0.38
0.38
0.76
9
60
A
GLU
0.73
0.33
0.67
9
61
A
LEU
0.75
0.70
0.50
9
62
A
THR
0.61
0.33
0.63
9
63
A
LYS
0.37
0.25
0.71
10
64
A
LEU
0.77
0.70
0.38
10
66
A
ALA
0.74
0.38
0.58
4
68
A
LEU
0.87
0.70
0.28
10
69
A
LYS
0.89
0.25
0.58
10
70
A
LYS
0.51
0.25
0.72
10
71
A
LYS
0.57
0.25
0.64
10
72
A
CYS
0.77
0.64
0.61
10
73
A
GLY
0.85
0.41
0.73
10
74
A
CYS
0.71
0.64
0.73
10
75
A
GLY
0.96
0.41
0.62
10
76
A
GLY
0.96
0.41
0.50
10
77
A
ALA
0.84
0.38
0.55
10
78
A
VAL
0.65
0.56
0.54
10
79
A
LYS
0.82
0.25
0.66
10
80
A
ASP
0.58
0.32
0.70
10
81
A
GLY
0.67
0.41
0.52
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.40
10
85
A
ILE
0.80
0.64
0.27
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.47
10
88
A
ASP
0.78
0.32
0.56
10
89
A
LYS
0.79
0.25
0.60
1
90
A
ARG
0.64
0.51
0.56
10
91
A
ASP
0.51
0.32
0.64
9
92
A
LEU
0.67
0.70
0.55
9
93
A
LEU
0.61
0.70
0.26
10
94
A
LYS
0.51
0.25
0.59
9
95
A
SER
0.39
0.36
0.63
9
96
A
LEU
0.42
0.70
0.38
10
98
A
GLU
0.44
0.33
0.66
9
100
A
LYS
0.51
0.25
0.59
10
101
A
GLY
0.84
0.41
0.72
4
102
A
MET
0.71
0.66
0.59
9
103
A
LYS
0.36
0.25
0.67
4
104
A
VAL
0.53
0.56
0.44
9
106
A
LEU
0.43
0.70
0.51
2
31
A
ASP
0.57
0.32
0.75
10
33
A
VAL
0.31
0.56
0.51
10
35
A
ARG
0.64
0.51
0.40
10
38
A
ARG
0.56
0.51
0.53
10
39
A
GLN
0.57
0.43
0.56
10
41
A
SER
0.60
0.36
0.76
9
42
A
GLY
0.81
0.41
0.80
9
43
A
ARG
0.86
0.51
0.85
9
44
A
LYS
0.67
0.25
0.87
9
45
A
GLY
0.87
0.41
0.80
9
46
A
LYS
0.88
0.25
0.74
9
47
A
GLY
0.57
0.41
0.59
1
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.35
10
53
A
GLY
0.93
0.41
0.48
10
54
A
VAL
0.77
0.56
0.40
10
55
A
ASP
0.63
0.32
0.66
10
56
A
LEU
0.64
0.70
0.62
10
57
A
ASP
0.38
0.32
0.77
10
58
A
ASP
0.38
0.32
0.76
10
59
A
ALA
0.38
0.38
0.77
10
60
A
GLU
0.73
0.33
0.65
10
61
A
LEU
0.75
0.70
0.53
10
62
A
THR
0.61
0.33
0.67
10
63
A
LYS
0.37
0.25
0.68
10
64
A
LEU
0.77
0.70
0.37
10
66
A
ALA
0.74
0.38
0.62
2
69
A
LYS
0.89
0.25
0.63
10
70
A
LYS
0.51
0.25
0.74
10
72
A
CYS
0.77
0.64
0.63
10
73
A
GLY
0.85
0.41
0.72
10
74
A
CYS
0.71
0.64
0.74
10
75
A
GLY
0.96
0.41
0.66
10
76
A
GLY
0.96
0.41
0.55
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.64
10
80
A
ASP
0.58
0.32
0.71
10
81
A
GLY
0.67
0.41
0.59
10
82
A
VAL
0.60
0.56
0.53
10
84
A
GLU
0.83
0.33
0.44
10
85
A
ILE
0.80
0.64
0.23
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.49
10
88
A
ASP
0.78
0.32
0.56
10
89
A
LYS
0.79
0.25
0.60
4
90
A
ARG
0.64
0.51
0.56
10
91
A
ASP
0.51
0.32
0.63
10
92
A
LEU
0.67
0.70
0.58
10
93
A
LEU
0.61
0.70
0.26
10
94
A
LYS
0.51
0.25
0.60
10
95
A
SER
0.39
0.36
0.64
10
96
A
LEU
0.42
0.70
0.40
10
98
A
GLU
0.44
0.33
0.66
10
99
A
ALA
0.42
0.38
0.68
10
101
A
GLY
0.84
0.41
0.71
10
102
A
MET
0.71
0.66
0.55
10
104
A
VAL
0.53
0.56
0.43
10
106
A
LEU
0.43
0.70
0.51
10
31
A
ASP
0.57
0.32
0.74
10
32
A
GLY
0.76
0.41
0.61
10
33
A
VAL
0.31
0.56
0.53
10
35
A
ARG
0.64
0.51
0.40
10
38
A
ARG
0.56
0.51
0.43
1
39
A
GLN
0.57
0.43
0.56
10
41
A
SER
0.60
0.36
0.73
10
42
A
GLY
0.81
0.41
0.77
10
43
A
ARG
0.86
0.51
0.86
10
44
A
LYS
0.67
0.25
0.81
10
45
A
GLY
0.87
0.41
0.76
10
46
A
LYS
0.88
0.25
0.72
10
48
A
VAL
0.81
0.56
0.47
10
50
A
LEU
0.57
0.70
0.33
10
53
A
GLY
0.93
0.41
0.45
10
54
A
VAL
0.77
0.56
0.34
10
55
A
ASP
0.63
0.32
0.62
10
56
A
LEU
0.64
0.70
0.61
10
57
A
ASP
0.38
0.32
0.77
10
58
A
ASP
0.38
0.32
0.74
10
59
A
ALA
0.38
0.38
0.74
10
61
A
LEU
0.75
0.70
0.46
10
64
A
LEU
0.77
0.70
0.31
10
66
A
ALA
0.74
0.38
0.58
6
68
A
LEU
0.87
0.70
0.23
10
69
A
LYS
0.89
0.25
0.64
10
70
A
LYS
0.51
0.25
0.70
10
71
A
LYS
0.57
0.25
0.64
10
72
A
CYS
0.77
0.64
0.51
10
73
A
GLY
0.85
0.41
0.69
10
74
A
CYS
0.71
0.64
0.66
10
75
A
GLY
0.96
0.41
0.56
10
76
A
GLY
0.96
0.41
0.62
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.58
10
79
A
LYS
0.82
0.25
0.70
10
80
A
ASP
0.58
0.32
0.71
10
81
A
GLY
0.67
0.41
0.57
10
82
A
VAL
0.60
0.56
0.51
10
84
A
GLU
0.83
0.33
0.42
10
85
A
ILE
0.80
0.64
0.27
10
86
A
GLN
1.00
0.43
0.55
10
87
A
GLY
0.95
0.41
0.43
10
88
A
ASP
0.78
0.32
0.52
10
90
A
ARG
0.64
0.51
0.38
10
91
A
ASP
0.51
0.32
0.54
10
92
A
LEU
0.67
0.70
0.51
6
95
A
SER
0.39
0.36
0.54
6
96
A
LEU
0.42
0.70
0.32
10
98
A
GLU
0.44
0.33
0.61
10
99
A
ALA
0.42
0.38
0.61
1
101
A
GLY
0.84
0.41
0.65
10
102
A
MET
0.71
0.66
0.47
10
104
A
VAL
0.53
0.56
0.39
10
106
A
LEU
0.43
0.70
0.47
5
107
A
ALA
0.44
0.38
0.50
5
108
A
GLY
0.69
0.41
0.60
5
109
A
GLY
0.66
0.41
0.70
5
29
A
LYS
0.24
0.25
0.82
6
31
A
ASP
0.57
0.32
0.78
4
32
A
GLY
0.76
0.41
0.65
10
33
A
VAL
0.31
0.56
0.57
10
35
A
ARG
0.64
0.51
0.43
10
38
A
ARG
0.56
0.51
0.52
10
39
A
GLN
0.57
0.43
0.56
10
41
A
SER
0.60
0.36
0.75
10
42
A
GLY
0.81
0.41
0.82
10
43
A
ARG
0.86
0.51
0.87
10
44
A
LYS
0.67
0.25
0.76
10
45
A
GLY
0.87
0.41
0.80
10
46
A
LYS
0.88
0.25
0.75
10
48
A
VAL
0.81
0.56
0.51
10
50
A
LEU
0.57
0.70
0.33
10
51
A
ILE
0.65
0.64
0.00
10
53
A
GLY
0.93
0.41
0.47
10
54
A
VAL
0.77
0.56
0.36
10
55
A
ASP
0.63
0.32
0.63
10
56
A
LEU
0.64
0.70
0.61
10
57
A
ASP
0.38
0.32
0.75
10
58
A
ASP
0.38
0.32
0.75
10
59
A
ALA
0.38
0.38
0.76
10
60
A
GLU
0.73
0.33
0.65
9
61
A
LEU
0.75
0.70
0.51
10
64
A
LEU
0.77
0.70
0.39
10
66
A
ALA
0.74
0.38
0.60
1
68
A
LEU
0.87
0.70
0.31
10
69
A
LYS
0.89
0.25
0.66
10
70
A
LYS
0.51
0.25
0.74
10
71
A
LYS
0.57
0.25
0.65
9
72
A
CYS
0.77
0.64
0.56
10
73
A
GLY
0.85
0.41
0.71
10
74
A
CYS
0.71
0.64
0.69
10
75
A
GLY
0.96
0.41
0.65
10
76
A
GLY
0.96
0.41
0.60
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.67
10
80
A
ASP
0.58
0.32
0.67
10
81
A
GLY
0.67
0.41
0.54
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.46
10
85
A
ILE
0.80
0.64
0.37
10
86
A
GLN
1.00
0.43
0.57
10
87
A
GLY
0.95
0.41
0.45
10
88
A
ASP
0.78
0.32
0.58
10
90
A
ARG
0.64
0.51
0.53
10
91
A
ASP
0.51
0.32
0.60
10
92
A
LEU
0.67
0.70
0.55
10
93
A
LEU
0.61
0.70
0.22
10
95
A
SER
0.39
0.36
0.60
10
96
A
LEU
0.42
0.70
0.42
10
98
A
GLU
0.44
0.33
0.65
10
99
A
ALA
0.42
0.38
0.67
6
101
A
GLY
0.84
0.41
0.70
6
102
A
MET
0.71
0.66
0.53
10
103
A
LYS
0.36
0.25
0.68
6
104
A
VAL
0.53
0.56
0.47
10
106
A
LEU
0.43
0.70
0.55
3
108
A
GLY
0.69
0.41
0.62
3
30
A
GLY
0.44
0.41
0.79
1
31
A
ASP
0.57
0.32
0.78
9
32
A
GLY
0.76
0.41
0.63
10
33
A
VAL
0.31
0.56
0.51
10
35
A
ARG
0.64
0.51
0.41
10
38
A
ARG
0.56
0.51
0.48
10
39
A
GLN
0.57
0.43
0.58
10
41
A
SER
0.60
0.36
0.76
10
42
A
GLY
0.81
0.41
0.78
10
43
A
ARG
0.86
0.51
0.85
10
44
A
LYS
0.67
0.25
0.86
10
45
A
GLY
0.87
0.41
0.74
10
46
A
LYS
0.88
0.25
0.75
10
47
A
GLY
0.57
0.41
0.57
2
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.32
10
53
A
GLY
0.93
0.41
0.48
10
54
A
VAL
0.77
0.56
0.37
10
55
A
ASP
0.63
0.32
0.64
10
56
A
LEU
0.64
0.70
0.59
10
57
A
ASP
0.38
0.32
0.75
10
58
A
ASP
0.38
0.32
0.74
10
59
A
ALA
0.38
0.38
0.76
10
61
A
LEU
0.75
0.70
0.49
10
62
A
THR
0.61
0.33
0.65
8
64
A
LEU
0.77
0.70
0.34
10
66
A
ALA
0.74
0.38
0.61
5
68
A
LEU
0.87
0.70
0.31
10
69
A
LYS
0.89
0.25
0.63
10
70
A
LYS
0.51
0.25
0.72
10
72
A
CYS
0.77
0.64
0.60
10
73
A
GLY
0.85
0.41
0.74
10
74
A
CYS
0.71
0.64
0.74
10
75
A
GLY
0.96
0.41
0.62
10
76
A
GLY
0.96
0.41
0.56
10
77
A
ALA
0.84
0.38
0.56
10
78
A
VAL
0.65
0.56
0.60
10
79
A
LYS
0.82
0.25
0.67
10
80
A
ASP
0.58
0.32
0.69
10
81
A
GLY
0.67
0.41
0.52
10
82
A
VAL
0.60
0.56
0.48
10
84
A
GLU
0.83
0.33
0.42
10
85
A
ILE
0.80
0.64
0.28
10
86
A
GLN
1.00
0.43
0.56
10
87
A
GLY
0.95
0.41
0.47
10
88
A
ASP
0.78
0.32
0.53
10
89
A
LYS
0.79
0.25
0.54
2
90
A
ARG
0.64
0.51
0.44
10
91
A
ASP
0.51
0.32
0.59
5
92
A
LEU
0.67
0.70
0.52
5
94
A
LYS
0.51
0.25
0.54
4
95
A
SER
0.39
0.36
0.58
5
96
A
LEU
0.42
0.70
0.37
10
98
A
GLU
0.44
0.33
0.63
9
99
A
ALA
0.42
0.38
0.65
1
101
A
GLY
0.84
0.41
0.71
9
102
A
MET
0.71
0.66
0.55
10
103
A
LYS
0.36
0.25
0.68
8
104
A
VAL
0.53
0.56
0.44
9
106
A
LEU
0.43
0.70
0.40
3
107
A
ALA
0.44
0.38
0.51
3
108
A
GLY
0.69
0.41
0.65
2
109
A
GLY
0.66
0.41
0.70
2
32
A
GLY
0.76
0.41
0.63
10
33
A
VAL
0.31
0.56
0.55
10
35
A
ARG
0.64
0.51
0.38
10
38
A
ARG
0.56
0.51
0.52
10
39
A
GLN
0.57
0.43
0.54
10
41
A
SER
0.60
0.36
0.74
10
42
A
GLY
0.81
0.41
0.80
10
43
A
ARG
0.86
0.51
0.87
10
44
A
LYS
0.67
0.25
0.88
10
45
A
GLY
0.87
0.41
0.78
10
46
A
LYS
0.88
0.25
0.74
10
47
A
GLY
0.57
0.41
0.59
1
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.33
10
53
A
GLY
0.93
0.41
0.46
10
54
A
VAL
0.77
0.56
0.36
9
55
A
ASP
0.63
0.32
0.64
10
56
A
LEU
0.64
0.70
0.64
10
57
A
ASP
0.38
0.32
0.77
8
58
A
ASP
0.38
0.32
0.76
8
59
A
ALA
0.38
0.38
0.77
10
60
A
GLU
0.73
0.33
0.70
10
64
A
LEU
0.77
0.70
0.41
10
69
A
LYS
0.89
0.25
0.60
10
70
A
LYS
0.51
0.25
0.73
10
72
A
CYS
0.77
0.64
0.62
10
73
A
GLY
0.85
0.41
0.74
10
74
A
CYS
0.71
0.64
0.73
10
75
A
GLY
0.96
0.41
0.66
10
76
A
GLY
0.96
0.41
0.59
10
77
A
ALA
0.84
0.38
0.57
10
78
A
VAL
0.65
0.56
0.59
10
79
A
LYS
0.82
0.25
0.65
10
80
A
ASP
0.58
0.32
0.72
10
81
A
GLY
0.67
0.41
0.57
10
82
A
VAL
0.60
0.56
0.51
10
84
A
GLU
0.83
0.33
0.40
10
85
A
ILE
0.80
0.64
0.29
10
86
A
GLN
1.00
0.43
0.55
10
87
A
GLY
0.95
0.41
0.44
10
88
A
ASP
0.78
0.32
0.55
10
89
A
LYS
0.79
0.25
0.58
10
90
A
ARG
0.64
0.51
0.48
10
91
A
ASP
0.51
0.32
0.58
10
92
A
LEU
0.67
0.70
0.54
10
93
A
LEU
0.61
0.70
0.22
10
95
A
SER
0.39
0.36
0.61
10
96
A
LEU
0.42
0.70
0.39
10
98
A
GLU
0.44
0.33
0.61
10
99
A
ALA
0.42
0.38
0.66
10
100
A
LYS
0.51
0.25
0.57
10
101
A
GLY
0.84
0.41
0.69
10
102
A
MET
0.71
0.66
0.54
10
104
A
VAL
0.53
0.56
0.41
10
106
A
LEU
0.43
0.70
0.48
10
108
A
GLY
0.69
0.41
0.58
3
109
A
GLY
0.66
0.41
0.71
3
32
A
GLY
0.76
0.41
0.62
8
33
A
VAL
0.31
0.56
0.56
10
35
A
ARG
0.64
0.51
0.42
10
39
A
GLN
0.57
0.43
0.56
10
41
A
SER
0.60
0.36
0.74
10
42
A
GLY
0.81
0.41
0.82
10
43
A
ARG
0.86
0.51
0.87
10
44
A
LYS
0.67
0.25
0.82
10
45
A
GLY
0.87
0.41
0.79
10
46
A
LYS
0.88
0.25
0.73
10
47
A
GLY
0.57
0.41
0.58
2
48
A
VAL
0.81
0.56
0.50
10
49
A
CYS
0.90
0.64
0.22
10
50
A
LEU
0.57
0.70
0.33
10
53
A
GLY
0.93
0.41
0.46
6
54
A
VAL
0.77
0.56
0.36
10
56
A
LEU
0.64
0.70
0.60
10
57
A
ASP
0.38
0.32
0.75
9
58
A
ASP
0.38
0.32
0.75
9
59
A
ALA
0.38
0.38
0.76
10
61
A
LEU
0.75
0.70
0.53
10
62
A
THR
0.61
0.33
0.66
6
64
A
LEU
0.77
0.70
0.37
10
69
A
LYS
0.89
0.25
0.63
10
70
A
LYS
0.51
0.25
0.74
10
72
A
CYS
0.77
0.64
0.62
10
73
A
GLY
0.85
0.41
0.75
10
74
A
CYS
0.71
0.64
0.77
10
75
A
GLY
0.96
0.41
0.67
10
76
A
GLY
0.96
0.41
0.58
10
77
A
ALA
0.84
0.38
0.55
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.69
10
80
A
ASP
0.58
0.32
0.67
10
81
A
GLY
0.67
0.41
0.47
1
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.43
10
85
A
ILE
0.80
0.64
0.31
10
86
A
GLN
1.00
0.43
0.55
10
87
A
GLY
0.95
0.41
0.46
10
88
A
ASP
0.78
0.32
0.55
10
89
A
LYS
0.79
0.25
0.58
6
90
A
ARG
0.64
0.51
0.48
10
91
A
ASP
0.51
0.32
0.59
10
92
A
LEU
0.67
0.70
0.56
10
93
A
LEU
0.61
0.70
0.23
10
94
A
LYS
0.51
0.25
0.55
2
95
A
SER
0.39
0.36
0.60
10
96
A
LEU
0.42
0.70
0.37
10
98
A
GLU
0.44
0.33
0.64
10
99
A
ALA
0.42
0.38
0.66
10
100
A
LYS
0.51
0.25
0.62
7
101
A
GLY
0.84
0.41
0.70
10
102
A
MET
0.71
0.66
0.53
10
103
A
LYS
0.36
0.25
0.67
8
104
A
VAL
0.53
0.56
0.41
10
106
A
LEU
0.43
0.70
0.49
6
31
A
ASP
0.57
0.32
0.76
10
32
A
GLY
0.76
0.41
0.63
10
33
A
VAL
0.31
0.56
0.59
10
35
A
ARG
0.64
0.51
0.43
10
38
A
ARG
0.56
0.51
0.53
1
39
A
GLN
0.57
0.43
0.53
10
41
A
SER
0.60
0.36
0.72
10
42
A
GLY
0.81
0.41
0.79
10
43
A
ARG
0.86
0.51
0.87
10
44
A
LYS
0.67
0.25
0.87
10
45
A
GLY
0.87
0.41
0.78
10
46
A
LYS
0.88
0.25
0.72
10
47
A
GLY
0.57
0.41
0.59
1
48
A
VAL
0.81
0.56
0.48
10
50
A
LEU
0.57
0.70
0.34
10
53
A
GLY
0.93
0.41
0.47
10
54
A
VAL
0.77
0.56
0.40
10
55
A
ASP
0.63
0.32
0.67
10
56
A
LEU
0.64
0.70
0.65
10
57
A
ASP
0.38
0.32
0.79
10
58
A
ASP
0.38
0.32
0.78
10
59
A
ALA
0.38
0.38
0.76
10
60
A
GLU
0.73
0.33
0.64
2
61
A
LEU
0.75
0.70
0.55
10
63
A
LYS
0.37
0.25
0.70
8
64
A
LEU
0.77
0.70
0.41
10
66
A
ALA
0.74
0.38
0.60
4
69
A
LYS
0.89
0.25
0.62
10
70
A
LYS
0.51
0.25
0.73
10
72
A
CYS
0.77
0.64
0.61
10
73
A
GLY
0.85
0.41
0.74
10
74
A
CYS
0.71
0.64
0.76
10
75
A
GLY
0.96
0.41
0.67
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.64
10
80
A
ASP
0.58
0.32
0.72
10
81
A
GLY
0.67
0.41
0.59
10
82
A
VAL
0.60
0.56
0.50
10
84
A
GLU
0.83
0.33
0.41
10
85
A
ILE
0.80
0.64
0.27
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.50
10
88
A
ASP
0.78
0.32
0.51
10
90
A
ARG
0.64
0.51
0.50
10
91
A
ASP
0.51
0.32
0.58
9
92
A
LEU
0.67
0.70
0.56
9
93
A
LEU
0.61
0.70
0.20
10
95
A
SER
0.39
0.36
0.58
9
96
A
LEU
0.42
0.70
0.39
10
98
A
GLU
0.44
0.33
0.64
10
101
A
GLY
0.84
0.41
0.69
10
102
A
MET
0.71
0.66
0.52
10
103
A
LYS
0.36
0.25
0.69
4
104
A
VAL
0.53
0.56
0.40
10
106
A
LEU
0.43
0.70
0.50
9
107
A
ALA
0.44
0.38
0.56
6
108
A
GLY
0.69
0.41
0.67
6
109
A
GLY
0.66
0.41
0.73
6
30
A
GLY
0.44
0.41
0.78
8
31
A
ASP
0.57
0.32
0.75
10
32
A
GLY
0.76
0.41
0.60
10
33
A
VAL
0.31
0.56
0.52
10
35
A
ARG
0.64
0.51
0.38
10
39
A
GLN
0.57
0.43
0.54
10
41
A
SER
0.60
0.36
0.72
10
42
A
GLY
0.81
0.41
0.78
10
43
A
ARG
0.86
0.51
0.85
10
44
A
LYS
0.67
0.25
0.86
10
45
A
GLY
0.87
0.41
0.74
10
46
A
LYS
0.88
0.25
0.72
10
47
A
GLY
0.57
0.41
0.55
1
48
A
VAL
0.81
0.56
0.44
10
50
A
LEU
0.57
0.70
0.31
10
53
A
GLY
0.93
0.41
0.50
10
54
A
VAL
0.77
0.56
0.40
10
55
A
ASP
0.63
0.32
0.65
10
56
A
LEU
0.64
0.70
0.63
10
57
A
ASP
0.38
0.32
0.75
10
58
A
ASP
0.38
0.32
0.73
10
59
A
ALA
0.38
0.38
0.75
10
60
A
GLU
0.73
0.33
0.65
10
61
A
LEU
0.75
0.70
0.49
10
63
A
LYS
0.37
0.25
0.67
9
64
A
LEU
0.77
0.70
0.31
10
66
A
ALA
0.74
0.38
0.58
8
68
A
LEU
0.87
0.70
0.27
10
69
A
LYS
0.89
0.25
0.62
10
70
A
LYS
0.51
0.25
0.73
10
72
A
CYS
0.77
0.64
0.59
10
73
A
GLY
0.85
0.41
0.74
10
74
A
CYS
0.71
0.64
0.76
10
75
A
GLY
0.96
0.41
0.66
10
76
A
GLY
0.96
0.41
0.54
10
77
A
ALA
0.84
0.38
0.55
10
78
A
VAL
0.65
0.56
0.54
10
79
A
LYS
0.82
0.25
0.66
10
80
A
ASP
0.58
0.32
0.72
10
81
A
GLY
0.67
0.41
0.60
10
82
A
VAL
0.60
0.56
0.50
10
84
A
GLU
0.83
0.33
0.38
10
85
A
ILE
0.80
0.64
0.24
10
86
A
GLN
1.00
0.43
0.51
10
87
A
GLY
0.95
0.41
0.39
10
88
A
ASP
0.78
0.32
0.48
10
89
A
LYS
0.79
0.25
0.56
4
90
A
ARG
0.64
0.51
0.41
10
91
A
ASP
0.51
0.32
0.60
10
92
A
LEU
0.67
0.70
0.53
10
93
A
LEU
0.61
0.70
0.21
10
94
A
LYS
0.51
0.25
0.59
10
95
A
SER
0.39
0.36
0.62
10
96
A
LEU
0.42
0.70
0.37
10
98
A
GLU
0.44
0.33
0.61
10
99
A
ALA
0.42
0.38
0.65
9
101
A
GLY
0.84
0.41
0.68
8
102
A
MET
0.71
0.66
0.52
10
103
A
LYS
0.36
0.25
0.66
8
104
A
VAL
0.53
0.56
0.40
10
106
A
LEU
0.43
0.70
0.50
6
108
A
GLY
0.69
0.41
0.56
6
109
A
GLY
0.66
0.41
0.69
6
110
A
LEU
0.02
0.70
0.75
6
30
A
GLY
0.44
0.41
0.78
9
32
A
GLY
0.76
0.41
0.62
10
33
A
VAL
0.31
0.56
0.56
10
35
A
ARG
0.64
0.51
0.47
10
38
A
ARG
0.56
0.51
0.51
10
39
A
GLN
0.57
0.43
0.57
10
40
A
THR
0.53
0.33
0.70
10
41
A
SER
0.60
0.36
0.72
10
42
A
GLY
0.81
0.41
0.81
10
43
A
ARG
0.86
0.51
0.85
10
44
A
LYS
0.67
0.25
0.81
10
45
A
GLY
0.87
0.41
0.69
10
46
A
LYS
0.88
0.25
0.79
10
48
A
VAL
0.81
0.56
0.50
10
50
A
LEU
0.57
0.70
0.35
10
53
A
GLY
0.93
0.41
0.46
10
54
A
VAL
0.77
0.56
0.40
10
55
A
ASP
0.63
0.32
0.63
10
56
A
LEU
0.64
0.70
0.59
10
57
A
ASP
0.38
0.32
0.78
10
58
A
ASP
0.38
0.32
0.75
10
59
A
ALA
0.38
0.38
0.77
10
60
A
GLU
0.73
0.33
0.67
10
61
A
LEU
0.75
0.70
0.51
10
62
A
THR
0.61
0.33
0.66
9
64
A
LEU
0.77
0.70
0.39
10
65
A
ALA
0.66
0.38
0.44
3
66
A
ALA
0.74
0.38
0.62
2
68
A
LEU
0.87
0.70
0.29
10
69
A
LYS
0.89
0.25
0.65
10
70
A
LYS
0.51
0.25
0.73
10
72
A
CYS
0.77
0.64
0.58
10
73
A
GLY
0.85
0.41
0.74
10
74
A
CYS
0.71
0.64
0.72
10
75
A
GLY
0.96
0.41
0.60
10
76
A
GLY
0.96
0.41
0.53
10
77
A
ALA
0.84
0.38
0.55
10
78
A
VAL
0.65
0.56
0.58
10
79
A
LYS
0.82
0.25
0.64
10
80
A
ASP
0.58
0.32
0.70
10
81
A
GLY
0.67
0.41
0.55
10
82
A
VAL
0.60
0.56
0.49
10
84
A
GLU
0.83
0.33
0.41
10
85
A
ILE
0.80
0.64
0.26
10
86
A
GLN
1.00
0.43
0.56
10
87
A
GLY
0.95
0.41
0.50
10
88
A
ASP
0.78
0.32
0.59
10
89
A
LYS
0.79
0.25
0.60
1
90
A
ARG
0.64
0.51
0.55
10
91
A
ASP
0.51
0.32
0.62
2
92
A
LEU
0.67
0.70
0.55
2
95
A
SER
0.39
0.36
0.61
1
96
A
LEU
0.42
0.70
0.40
10
98
A
GLU
0.44
0.33
0.64
9
99
A
ALA
0.42
0.38
0.66
9
101
A
GLY
0.84
0.41
0.69
9
102
A
MET
0.71
0.66
0.52
10
104
A
VAL
0.53
0.56
0.43
9
106
A
LEU
0.43
0.70
0.54
1
108
A
GLY
0.69
0.41
0.63
1
30
A
GLY
0.44
0.41
0.77
6
31
A
ASP
0.57
0.32
0.74
8
33
A
VAL
0.31
0.56
0.47
9
35
A
ARG
0.64
0.51
0.41
9
38
A
ARG
0.56
0.51
0.54
10
39
A
GLN
0.57
0.43
0.57
10
41
A
SER
0.60
0.36
0.69
10
42
A
GLY
0.81
0.41
0.76
10
43
A
ARG
0.86
0.51
0.85
10
44
A
LYS
0.67
0.25
0.83
10
45
A
GLY
0.87
0.41
0.76
10
46
A
LYS
0.88
0.25
0.75
10
48
A
VAL
0.81
0.56
0.47
10
50
A
LEU
0.57
0.70
0.34
10
53
A
GLY
0.93
0.41
0.44
5
54
A
VAL
0.77
0.56
0.37
9
55
A
ASP
0.63
0.32
0.65
9
56
A
LEU
0.64
0.70
0.62
9
57
A
ASP
0.38
0.32
0.76
9
58
A
ASP
0.38
0.32
0.73
9
59
A
ALA
0.38
0.38
0.75
9
60
A
GLU
0.73
0.33
0.65
9
61
A
LEU
0.75
0.70
0.48
10
64
A
LEU
0.77
0.70
0.33
10
66
A
ALA
0.74
0.38
0.58
5
68
A
LEU
0.87
0.70
0.28
10
69
A
LYS
0.89
0.25
0.58
10
70
A
LYS
0.51
0.25
0.71
10
72
A
CYS
0.77
0.64
0.51
10
73
A
GLY
0.85
0.41
0.68
10
74
A
CYS
0.71
0.64
0.65
10
75
A
GLY
0.96
0.41
0.63
10
76
A
GLY
0.96
0.41
0.60
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.66
10
80
A
ASP
0.58
0.32
0.65
10
81
A
GLY
0.67
0.41
0.52
10
82
A
VAL
0.60
0.56
0.52
10
84
A
GLU
0.83
0.33
0.42
10
85
A
ILE
0.80
0.64
0.25
10
86
A
GLN
1.00
0.43
0.55
10
87
A
GLY
0.95
0.41
0.49
10
88
A
ASP
0.78
0.32
0.56
9
90
A
ARG
0.64
0.51
0.44
10
91
A
ASP
0.51
0.32
0.59
9
92
A
LEU
0.67
0.70
0.56
9
93
A
LEU
0.61
0.70
0.18
10
94
A
LYS
0.51
0.25
0.56
9
95
A
SER
0.39
0.36
0.59
9
96
A
LEU
0.42
0.70
0.38
9
98
A
GLU
0.44
0.33
0.65
9
101
A
GLY
0.84
0.41
0.69
8
102
A
MET
0.71
0.66
0.52
9
103
A
LYS
0.36
0.25
0.68
8
104
A
VAL
0.53
0.56
0.43
9
32
A
GLY
0.76
0.41
0.61
7
33
A
VAL
0.31
0.56
0.58
9
35
A
ARG
0.64
0.51
0.43
9
39
A
GLN
0.57
0.43
0.57
10
41
A
SER
0.60
0.36
0.75
4
42
A
GLY
0.81
0.41
0.82
4
43
A
ARG
0.86
0.51
0.88
9
44
A
LYS
0.67
0.25
0.85
9
45
A
GLY
0.87
0.41
0.76
9
46
A
LYS
0.88
0.25
0.74
9
47
A
GLY
0.57
0.41
0.59
1
48
A
VAL
0.81
0.56
0.48
10
50
A
LEU
0.57
0.70
0.31
10
53
A
GLY
0.93
0.41
0.47
9
54
A
VAL
0.77
0.56
0.38
9
55
A
ASP
0.63
0.32
0.61
8
56
A
LEU
0.64
0.70
0.58
9
57
A
ASP
0.38
0.32
0.76
9
58
A
ASP
0.38
0.32
0.75
9
59
A
ALA
0.38
0.38
0.76
9
60
A
GLU
0.73
0.33
0.66
8
61
A
LEU
0.75
0.70
0.50
10
62
A
THR
0.61
0.33
0.65
6
64
A
LEU
0.77
0.70
0.37
10
66
A
ALA
0.74
0.38
0.59
4
68
A
LEU
0.87
0.70
0.30
10
69
A
LYS
0.89
0.25
0.63
10
70
A
LYS
0.51
0.25
0.73
9
71
A
LYS
0.57
0.25
0.69
9
72
A
CYS
0.77
0.64
0.54
10
73
A
GLY
0.85
0.41
0.69
10
74
A
CYS
0.71
0.64
0.68
10
75
A
GLY
0.96
0.41
0.65
10
76
A
GLY
0.96
0.41
0.58
10
77
A
ALA
0.84
0.38
0.60
10
78
A
VAL
0.65
0.56
0.56
10
79
A
LYS
0.82
0.25
0.67
10
80
A
ASP
0.58
0.32
0.66
10
81
A
GLY
0.67
0.41
0.52
10
82
A
VAL
0.60
0.56
0.49
10
84
A
GLU
0.83
0.33
0.42
10
86
A
GLN
1.00
0.43
0.56
10
87
A
GLY
0.95
0.41
0.49
10
88
A
ASP
0.78
0.32
0.56
10
89
A
LYS
0.79
0.25
0.46
5
90
A
ARG
0.64
0.51
0.52
10
91
A
ASP
0.51
0.32
0.59
5
92
A
LEU
0.67
0.70
0.55
5
94
A
LYS
0.51
0.25
0.56
3
95
A
SER
0.39
0.36
0.60
2
96
A
LEU
0.42
0.70
0.35
10
98
A
GLU
0.44
0.33
0.63
8
101
A
GLY
0.84
0.41
0.68
8
102
A
MET
0.71
0.66
0.51
9
103
A
LYS
0.36
0.25
0.67
7
104
A
VAL
0.53
0.56
0.40
8
31
A
ASP
0.57
0.32
0.77
9
32
A
GLY
0.76
0.41
0.63
9
33
A
VAL
0.31
0.56
0.56
10
35
A
ARG
0.64
0.51
0.44
10
39
A
GLN
0.57
0.43
0.60
10
41
A
SER
0.60
0.36
0.75
10
42
A
GLY
0.81
0.41
0.80
10
43
A
ARG
0.86
0.51
0.88
10
44
A
LYS
0.67
0.25
0.84
10
45
A
GLY
0.87
0.41
0.79
10
46
A
LYS
0.88
0.25
0.73
10
47
A
GLY
0.57
0.41
0.58
4
48
A
VAL
0.81
0.56
0.52
10
50
A
LEU
0.57
0.70
0.34
10
53
A
GLY
0.93
0.41
0.46
10
54
A
VAL
0.77
0.56
0.34
10
56
A
LEU
0.64
0.70
0.60
10
57
A
ASP
0.38
0.32
0.74
7
58
A
ASP
0.38
0.32
0.74
7
59
A
ALA
0.38
0.38
0.76
10
60
A
GLU
0.73
0.33
0.65
10
63
A
LYS
0.37
0.25
0.69
10
64
A
LEU
0.77
0.70
0.39
10
66
A
ALA
0.74
0.38
0.58
5
68
A
LEU
0.87
0.70
0.27
10
69
A
LYS
0.89
0.25
0.59
10
70
A
LYS
0.51
0.25
0.72
10
72
A
CYS
0.77
0.64
0.60
10
73
A
GLY
0.85
0.41
0.70
10
74
A
CYS
0.71
0.64
0.67
10
75
A
GLY
0.96
0.41
0.57
10
76
A
GLY
0.96
0.41
0.62
10
77
A
ALA
0.84
0.38
0.62
10
78
A
VAL
0.65
0.56
0.54
10
79
A
LYS
0.82
0.25
0.67
10
80
A
ASP
0.58
0.32
0.68
10
81
A
GLY
0.67
0.41
0.55
10
82
A
VAL
0.60
0.56
0.53
10
84
A
GLU
0.83
0.33
0.47
10
85
A
ILE
0.80
0.64
0.30
10
86
A
GLN
1.00
0.43
0.59
10
87
A
GLY
0.95
0.41
0.49
10
88
A
ASP
0.78
0.32
0.54
10
89
A
LYS
0.79
0.25
0.55
4
90
A
ARG
0.64
0.51
0.48
10
91
A
ASP
0.51
0.32
0.57
7
92
A
LEU
0.67
0.70
0.55
9
94
A
LYS
0.51
0.25
0.54
9
95
A
SER
0.39
0.36
0.58
8
96
A
LEU
0.42
0.70
0.38
10
98
A
GLU
0.44
0.33
0.65
10
99
A
ALA
0.42
0.38
0.66
10
101
A
GLY
0.84
0.41
0.70
10
102
A
MET
0.71
0.66
0.53
10
103
A
LYS
0.36
0.25
0.67
8
104
A
VAL
0.53
0.56
0.47
8
106
A
LEU
0.43
0.70
0.51
5
108
A
GLY
0.69
0.41
0.52
5
109
A
GLY
0.66
0.41
0.66
5
110
A
LEU
0.02
0.70
0.79
5
32
A
GLY
0.76
0.41
0.64
7
33
A
VAL
0.31
0.56
0.57
10
35
A
ARG
0.64
0.51
0.43
10
39
A
GLN
0.57
0.43
0.55
9
41
A
SER
0.60
0.36
0.73
10
42
A
GLY
0.81
0.41
0.80
5
43
A
ARG
0.86
0.51
0.88
2
44
A
LYS
0.67
0.25
0.86
5
45
A
GLY
0.87
0.41
0.76
5
46
A
LYS
0.88
0.25
0.74
5
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.36
10
53
A
GLY
0.93
0.41
0.44
9
54
A
VAL
0.77
0.56
0.36
10
56
A
LEU
0.64
0.70
0.59
10
57
A
ASP
0.38
0.32
0.78
10
58
A
ASP
0.38
0.32
0.77
10
59
A
ALA
0.38
0.38
0.77
10
60
A
GLU
0.73
0.33
0.68
10
61
A
LEU
0.75
0.70
0.54
10
62
A
THR
0.61
0.33
0.65
2
64
A
LEU
0.77
0.70
0.40
10
66
A
ALA
0.74
0.38
0.60
4
68
A
LEU
0.87
0.70
0.28
10
69
A
LYS
0.89
0.25
0.54
10
70
A
LYS
0.51
0.25
0.72
10
71
A
LYS
0.57
0.25
0.68
10
72
A
CYS
0.77
0.64
0.54
10
73
A
GLY
0.85
0.41
0.71
10
74
A
CYS
0.71
0.64
0.64
10
75
A
GLY
0.96
0.41
0.58
10
76
A
GLY
0.96
0.41
0.58
10
77
A
ALA
0.84
0.38
0.60
10
78
A
VAL
0.65
0.56
0.59
10
79
A
LYS
0.82
0.25
0.67
10
80
A
ASP
0.58
0.32
0.68
10
81
A
GLY
0.67
0.41
0.55
10
82
A
VAL
0.60
0.56
0.50
10
84
A
GLU
0.83
0.33
0.46
10
86
A
GLN
1.00
0.43
0.54
10
87
A
GLY
0.95
0.41
0.51
10
88
A
ASP
0.78
0.32
0.56
10
89
A
LYS
0.79
0.25
0.54
7
90
A
ARG
0.64
0.51
0.44
10
91
A
ASP
0.51
0.32
0.59
8
92
A
LEU
0.67
0.70
0.56
8
94
A
LYS
0.51
0.25
0.56
2
95
A
SER
0.39
0.36
0.61
7
96
A
LEU
0.42
0.70
0.41
10
98
A
GLU
0.44
0.33
0.67
10
99
A
ALA
0.42
0.38
0.68
2
100
A
LYS
0.51
0.25
0.62
2
101
A
GLY
0.84
0.41
0.70
10
102
A
MET
0.71
0.66
0.55
10
103
A
LYS
0.36
0.25
0.69
10
104
A
VAL
0.53
0.56
0.43
10
31
A
ASP
0.57
0.32
0.74
9
32
A
GLY
0.76
0.41
0.61
9
33
A
VAL
0.31
0.56
0.53
10
34
A
VAL
0.67
0.56
0.21
3
35
A
ARG
0.64
0.51
0.41
10
37
A
GLN
0.53
0.43
0.40
9
38
A
ARG
0.56
0.51
0.49
10
39
A
GLN
0.57
0.43
0.59
10
41
A
SER
0.60
0.36
0.76
5
42
A
GLY
0.81
0.41
0.82
3
43
A
ARG
0.86
0.51
0.87
5
44
A
LYS
0.67
0.25
0.80
5
45
A
GLY
0.87
0.41
0.80
5
46
A
LYS
0.88
0.25
0.74
5
48
A
VAL
0.81
0.56
0.49
10
50
A
LEU
0.57
0.70
0.35
10
53
A
GLY
0.93
0.41
0.46
10
54
A
VAL
0.77
0.56
0.38
10
56
A
LEU
0.64
0.70
0.61
10
57
A
ASP
0.38
0.32
0.75
10
58
A
ASP
0.38
0.32
0.75
10
59
A
ALA
0.38
0.38
0.76
10
60
A
GLU
0.73
0.33
0.67
10
61
A
LEU
0.75
0.70
0.49
10
64
A
LEU
0.77
0.70
0.41
10
66
A
ALA
0.74
0.38
0.60
2
68
A
LEU
0.87
0.70
0.26
10
69
A
LYS
0.89
0.25
0.61
10
70
A
LYS
0.51
0.25
0.72
10
72
A
CYS
0.77
0.64
0.54
10
73
A
GLY
0.85
0.41
0.69
10
74
A
CYS
0.71
0.64
0.69
10
75
A
GLY
0.96
0.41
0.61
10
76
A
GLY
0.96
0.41
0.59
10
77
A
ALA
0.84
0.38
0.58
10
78
A
VAL
0.65
0.56
0.55
10
79
A
LYS
0.82
0.25
0.70
10
80
A
ASP
0.58
0.32
0.69
10
81
A
GLY
0.67
0.41
0.58
10
82
A
VAL
0.60
0.56
0.50
10
84
A
GLU
0.83
0.33
0.42
10
85
A
ILE
0.80
0.64
0.32
10
86
A
GLN
1.00
0.43
0.58
10
87
A
GLY
0.95
0.41
0.50
10
88
A
ASP
0.78
0.32
0.51
10
89
A
LYS
0.79
0.25
0.53
2
90
A
ARG
0.64
0.51
0.45
10
91
A
ASP
0.51
0.32
0.57
10
92
A
LEU
0.67
0.70
0.53
10
93
A
LEU
0.61
0.70
0.16
10
95
A
SER
0.39
0.36
0.57
10
96
A
LEU
0.42
0.70
0.35
10
98
A
GLU
0.44
0.33
0.64
10
101
A
GLY
0.84
0.41
0.68
10
102
A
MET
0.71
0.66
0.52
10
103
A
LYS
0.36
0.25
0.67
10
104
A
VAL
0.53
0.56
0.41
10
106
A
LEU
0.43
0.70
0.47
10