Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1D8J chain A sc2

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
ALA
0.16
0.38
0.77
1
2
A
LEU
0.41
0.70
0.64
6
3
A
SER
0.40
0.36
0.80
1
4
A
GLY
0.56
0.41
0.75
1
5
A
SER
0.69
0.36
0.69
6
6
A
SER
0.66
0.36
0.62
6
7
A
GLY
0.59
0.41
0.55
6
8
A
TYR
0.59
0.80
0.53
6
10
A
PHE
1.00
1.00
0.47
10
11
A
GLY
0.65
0.41
0.44
10
12
A
VAL
0.61
0.56
0.29
10
13
A
LEU
0.90
0.70
0.20
10
14
A
ALA
0.81
0.38
0.38
10
15
A
LYS
0.79
0.25
0.45
10
17
A
VAL
0.98
0.56
0.21
9
18
A
ASN
0.63
0.39
0.44
10
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.44
5
22
A
THR
0.62
0.33
0.52
4
23
A
ARG
0.90
0.51
0.48
10
24
A
HIS
1.00
0.60
0.38
10
25
A
GLN
0.91
0.43
0.60
10
26
A
ARG
0.42
0.51
0.68
10
27
A
GLY
0.83
0.41
0.64
10
28
A
ASP
0.67
0.32
0.56
10
29
A
THR
0.60
0.33
0.50
10
30
A
HIS
0.70
0.60
0.53
10
31
A
PRO
0.82
0.47
0.48
10
32
A
LEU
1.00
0.70
0.35
10
34
A
LEU
0.65
0.70
0.27
10
35
A
ASP
0.24
0.32
0.50
10
36
A
GLU
0.94
0.33
0.49
10
39
A
ASP
0.86
0.32
0.55
10
40
A
GLU
0.94
0.33
0.50
10
41
A
THR
0.84
0.33
0.32
9
42
A
GLN
0.62
0.43
0.59
10
43
A
HIS
0.59
0.60
0.39
10
44
A
LEU
0.76
0.70
0.62
10
45
A
ASP
1.00
0.32
0.69
10
46
A
ILE
0.63
0.64
0.45
10
47
A
GLY
0.59
0.41
0.58
10
48
A
LEU
0.42
0.70
0.70
10
49
A
LYS
0.43
0.25
0.60
10
50
A
GLN
0.55
0.43
0.37
10
51
A
LYS
0.69
0.25
0.47
2
52
A
GLN
0.49
0.43
0.58
10
53
A
TRP
0.96
0.99
0.36
10
55
A
MET
0.50
0.66
0.44
10
56
A
THR
0.23
0.33
0.59
10
57
A
GLU
1.00
0.33
0.50
10
58
A
ALA
0.91
0.38
0.26
5
60
A
VAL
0.52
0.56
0.48
10
61
A
ASN
0.28
0.39
0.54
10
62
A
ASN
1.00
0.39
0.34
10
63
A
PRO
0.97
0.47
0.49
10
64
A
LYS
0.88
0.25
0.37
8
68
A
ILE
0.30
0.64
0.56
8
69
A
ASP
0.41
0.32
0.68
2
72
A
TYR
0.60
0.80
0.25
10
74
A
PHE
0.84
1.00
0.25
10
75
A
LYS
0.78
0.25
0.43
1
76
A
PRO
0.84
0.47
0.47
6
77
A
LYS
0.61
0.25
0.65
9
78
A
TYR
0.85
0.80
0.67
6
79
A
ASN
0.58
0.39
0.59
9
80
A
VAL
0.62
0.56
0.58
9
81
A
ARG
0.53
0.51
0.77
5
4
A
GLY
0.56
0.41
0.66
2
5
A
SER
0.69
0.36
0.60
7
6
A
SER
0.66
0.36
0.60
7
7
A
GLY
0.59
0.41
0.62
7
8
A
TYR
0.59
0.80
0.60
7
10
A
PHE
1.00
1.00
0.48
8
11
A
GLY
0.65
0.41
0.46
8
12
A
VAL
0.61
0.56
0.36
9
13
A
LEU
0.90
0.70
0.19
10
14
A
ALA
0.81
0.38
0.36
2
15
A
LYS
0.79
0.25
0.44
7
17
A
VAL
0.98
0.56
0.17
9
18
A
ASN
0.63
0.39
0.41
2
19
A
TYR
0.66
0.80
0.32
10
21
A
LYS
0.72
0.25
0.40
2
22
A
THR
0.62
0.33
0.51
3
23
A
ARG
0.90
0.51
0.44
10
24
A
HIS
1.00
0.60
0.38
10
25
A
GLN
0.91
0.43
0.53
10
26
A
ARG
0.42
0.51
0.66
10
27
A
GLY
0.83
0.41
0.64
10
28
A
ASP
0.67
0.32
0.57
10
29
A
THR
0.60
0.33
0.51
10
30
A
HIS
0.70
0.60
0.55
10
31
A
PRO
0.82
0.47
0.51
10
34
A
LEU
0.65
0.70
0.30
10
35
A
ASP
0.24
0.32
0.53
10
36
A
GLU
0.94
0.33
0.50
10
39
A
ASP
0.86
0.32
0.57
10
40
A
GLU
0.94
0.33
0.52
10
42
A
GLN
0.62
0.43
0.60
10
43
A
HIS
0.59
0.60
0.43
10
44
A
LEU
0.76
0.70
0.62
10
45
A
ASP
1.00
0.32
0.66
10
46
A
ILE
0.63
0.64
0.45
10
47
A
GLY
0.59
0.41
0.60
10
48
A
LEU
0.42
0.70
0.71
8
49
A
LYS
0.43
0.25
0.67
8
50
A
GLN
0.55
0.43
0.43
8
51
A
LYS
0.69
0.25
0.50
1
52
A
GLN
0.49
0.43
0.58
8
53
A
TRP
0.96
0.99
0.39
8
55
A
MET
0.50
0.66
0.43
7
56
A
THR
0.23
0.33
0.57
7
57
A
GLU
1.00
0.33
0.54
7
58
A
ALA
0.91
0.38
0.31
6
60
A
VAL
0.52
0.56
0.49
10
61
A
ASN
0.28
0.39
0.53
10
62
A
ASN
1.00
0.39
0.30
10
63
A
PRO
0.97
0.47
0.45
10
64
A
LYS
0.88
0.25
0.35
9
68
A
ILE
0.30
0.64
0.58
4
69
A
ASP
0.41
0.32
0.71
4
71
A
LYS
0.65
0.25
0.58
4
72
A
TYR
0.60
0.80
0.28
4
75
A
LYS
0.78
0.25
0.48
7
76
A
PRO
0.84
0.47
0.49
10
77
A
LYS
0.61
0.25
0.60
10
78
A
TYR
0.85
0.80
0.73
10
79
A
ASN
0.58
0.39
0.56
10
80
A
VAL
0.62
0.56
0.69
10
81
A
ARG
0.53
0.51
0.73
10
4
A
GLY
0.56
0.41
0.70
9
5
A
SER
0.69
0.36
0.62
9
6
A
SER
0.66
0.36
0.64
9
7
A
GLY
0.59
0.41
0.54
9
8
A
TYR
0.59
0.80
0.47
9
10
A
PHE
1.00
1.00
0.50
10
11
A
GLY
0.65
0.41
0.45
10
12
A
VAL
0.61
0.56
0.26
10
13
A
LEU
0.90
0.70
0.22
10
14
A
ALA
0.81
0.38
0.42
10
15
A
LYS
0.79
0.25
0.45
10
17
A
VAL
0.98
0.56
0.21
9
18
A
ASN
0.63
0.39
0.45
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.40
4
22
A
THR
0.62
0.33
0.50
10
23
A
ARG
0.90
0.51
0.48
10
24
A
HIS
1.00
0.60
0.33
10
25
A
GLN
0.91
0.43
0.53
10
26
A
ARG
0.42
0.51
0.65
10
27
A
GLY
0.83
0.41
0.62
10
28
A
ASP
0.67
0.32
0.54
10
29
A
THR
0.60
0.33
0.45
10
30
A
HIS
0.70
0.60
0.52
10
31
A
PRO
0.82
0.47
0.43
10
32
A
LEU
1.00
0.70
0.35
10
34
A
LEU
0.65
0.70
0.23
10
36
A
GLU
0.94
0.33
0.47
10
39
A
ASP
0.86
0.32
0.53
10
40
A
GLU
0.94
0.33
0.47
10
42
A
GLN
0.62
0.43
0.61
10
43
A
HIS
0.59
0.60
0.41
10
44
A
LEU
0.76
0.70
0.58
10
45
A
ASP
1.00
0.32
0.64
10
46
A
ILE
0.63
0.64
0.36
10
47
A
GLY
0.59
0.41
0.47
10
48
A
LEU
0.42
0.70
0.60
9
49
A
LYS
0.43
0.25
0.56
9
52
A
GLN
0.49
0.43
0.54
10
53
A
TRP
0.96
0.99
0.35
10
55
A
MET
0.50
0.66
0.42
10
56
A
THR
0.23
0.33
0.56
10
57
A
GLU
1.00
0.33
0.52
10
58
A
ALA
0.91
0.38
0.29
8
60
A
VAL
0.52
0.56
0.48
10
61
A
ASN
0.28
0.39
0.57
10
62
A
ASN
1.00
0.39
0.36
10
63
A
PRO
0.97
0.47
0.52
10
64
A
LYS
0.88
0.25
0.40
9
68
A
ILE
0.30
0.64
0.58
7
72
A
TYR
0.60
0.80
0.23
10
74
A
PHE
0.84
1.00
0.20
10
75
A
LYS
0.78
0.25
0.40
3
76
A
PRO
0.84
0.47
0.41
1
77
A
LYS
0.61
0.25
0.54
1
78
A
TYR
0.85
0.80
0.64
6
79
A
ASN
0.58
0.39
0.58
6
80
A
VAL
0.62
0.56
0.63
10
81
A
ARG
0.53
0.51
0.78
4
1
A
ALA
0.16
0.38
0.61
10
2
A
LEU
0.41
0.70
0.64
7
3
A
SER
0.40
0.36
0.70
7
4
A
GLY
0.56
0.41
0.64
7
5
A
SER
0.69
0.36
0.77
2
6
A
SER
0.66
0.36
0.71
2
7
A
GLY
0.59
0.41
0.58
7
8
A
TYR
0.59
0.80
0.54
8
10
A
PHE
1.00
1.00
0.46
8
11
A
GLY
0.65
0.41
0.44
7
12
A
VAL
0.61
0.56
0.28
10
13
A
LEU
0.90
0.70
0.15
10
14
A
ALA
0.81
0.38
0.37
1
15
A
LYS
0.79
0.25
0.43
7
17
A
VAL
0.98
0.56
0.17
10
18
A
ASN
0.63
0.39
0.42
10
19
A
TYR
0.66
0.80
0.28
10
21
A
LYS
0.72
0.25
0.39
3
22
A
THR
0.62
0.33
0.48
10
23
A
ARG
0.90
0.51
0.38
10
24
A
HIS
1.00
0.60
0.30
10
25
A
GLN
0.91
0.43
0.52
10
26
A
ARG
0.42
0.51
0.61
10
27
A
GLY
0.83
0.41
0.59
10
28
A
ASP
0.67
0.32
0.48
10
29
A
THR
0.60
0.33
0.43
4
30
A
HIS
0.70
0.60
0.51
10
31
A
PRO
0.82
0.47
0.46
10
33
A
THR
0.62
0.33
0.46
1
34
A
LEU
0.65
0.70
0.25
10
35
A
ASP
0.24
0.32
0.49
10
36
A
GLU
0.94
0.33
0.47
10
39
A
ASP
0.86
0.32
0.54
10
40
A
GLU
0.94
0.33
0.49
10
41
A
THR
0.84
0.33
0.35
9
42
A
GLN
0.62
0.43
0.61
10
43
A
HIS
0.59
0.60
0.40
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.62
10
46
A
ILE
0.63
0.64
0.42
10
47
A
GLY
0.59
0.41
0.55
10
48
A
LEU
0.42
0.70
0.68
6
49
A
LYS
0.43
0.25
0.63
6
50
A
GLN
0.55
0.43
0.38
10
52
A
GLN
0.49
0.43
0.55
10
53
A
TRP
0.96
0.99
0.34
10
55
A
MET
0.50
0.66
0.41
10
56
A
THR
0.23
0.33
0.53
10
57
A
GLU
1.00
0.33
0.46
10
60
A
VAL
0.52
0.56
0.46
10
61
A
ASN
0.28
0.39
0.52
10
62
A
ASN
1.00
0.39
0.32
10
63
A
PRO
0.97
0.47
0.51
10
64
A
LYS
0.88
0.25
0.39
10
68
A
ILE
0.30
0.64
0.53
3
69
A
ASP
0.41
0.32
0.69
3
71
A
LYS
0.65
0.25
0.55
3
72
A
TYR
0.60
0.80
0.24
3
74
A
PHE
0.84
1.00
0.18
10
75
A
LYS
0.78
0.25
0.42
7
76
A
PRO
0.84
0.47
0.41
3
77
A
LYS
0.61
0.25
0.60
10
78
A
TYR
0.85
0.80
0.57
10
79
A
ASN
0.58
0.39
0.65
9
80
A
VAL
0.62
0.56
0.60
8
81
A
ARG
0.53
0.51
0.77
8
6
A
SER
0.66
0.36
0.56
9
8
A
TYR
0.59
0.80
0.55
9
10
A
PHE
1.00
1.00
0.51
10
11
A
GLY
0.65
0.41
0.42
10
12
A
VAL
0.61
0.56
0.27
10
13
A
LEU
0.90
0.70
0.21
10
14
A
ALA
0.81
0.38
0.37
10
15
A
LYS
0.79
0.25
0.40
10
17
A
VAL
0.98
0.56
0.22
10
18
A
ASN
0.63
0.39
0.44
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.46
6
22
A
THR
0.62
0.33
0.53
10
23
A
ARG
0.90
0.51
0.50
10
24
A
HIS
1.00
0.60
0.41
10
25
A
GLN
0.91
0.43
0.62
10
26
A
ARG
0.42
0.51
0.71
10
27
A
GLY
0.83
0.41
0.66
10
28
A
ASP
0.67
0.32
0.53
10
29
A
THR
0.60
0.33
0.51
10
30
A
HIS
0.70
0.60
0.54
10
31
A
PRO
0.82
0.47
0.45
10
32
A
LEU
1.00
0.70
0.38
10
33
A
THR
0.62
0.33
0.48
2
36
A
GLU
0.94
0.33
0.49
10
39
A
ASP
0.86
0.32
0.55
10
40
A
GLU
0.94
0.33
0.49
10
42
A
GLN
0.62
0.43
0.59
10
43
A
HIS
0.59
0.60
0.38
10
44
A
LEU
0.76
0.70
0.61
10
45
A
ASP
1.00
0.32
0.67
10
46
A
ILE
0.63
0.64
0.42
10
47
A
GLY
0.59
0.41
0.56
10
48
A
LEU
0.42
0.70
0.67
9
49
A
LYS
0.43
0.25
0.67
9
50
A
GLN
0.55
0.43
0.41
9
52
A
GLN
0.49
0.43
0.58
10
53
A
TRP
0.96
0.99
0.41
9
55
A
MET
0.50
0.66
0.44
9
56
A
THR
0.23
0.33
0.57
9
57
A
GLU
1.00
0.33
0.54
9
60
A
VAL
0.52
0.56
0.47
9
61
A
ASN
0.28
0.39
0.51
9
62
A
ASN
1.00
0.39
0.32
9
63
A
PRO
0.97
0.47
0.47
9
64
A
LYS
0.88
0.25
0.38
9
67
A
VAL
0.36
0.56
0.46
4
68
A
ILE
0.30
0.64
0.55
4
69
A
ASP
0.41
0.32
0.69
4
70
A
GLY
0.63
0.41
0.59
2
71
A
LYS
0.65
0.25
0.56
10
74
A
PHE
0.84
1.00
0.26
10
75
A
LYS
0.78
0.25
0.39
1
76
A
PRO
0.84
0.47
0.44
10
77
A
LYS
0.61
0.25
0.61
4
78
A
TYR
0.85
0.80
0.57
4
79
A
ASN
0.58
0.39
0.58
4
80
A
VAL
0.62
0.56
0.70
4
81
A
ARG
0.53
0.51
0.77
1
3
A
SER
0.40
0.36
0.75
9
4
A
GLY
0.56
0.41
0.61
9
5
A
SER
0.69
0.36
0.71
9
6
A
SER
0.66
0.36
0.66
9
7
A
GLY
0.59
0.41
0.54
9
8
A
TYR
0.59
0.80
0.49
9
10
A
PHE
1.00
1.00
0.51
10
11
A
GLY
0.65
0.41
0.45
10
12
A
VAL
0.61
0.56
0.25
10
13
A
LEU
0.90
0.70
0.21
10
14
A
ALA
0.81
0.38
0.41
10
15
A
LYS
0.79
0.25
0.44
10
17
A
VAL
0.98
0.56
0.24
9
18
A
ASN
0.63
0.39
0.47
9
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.46
7
22
A
THR
0.62
0.33
0.54
10
23
A
ARG
0.90
0.51
0.49
10
24
A
HIS
1.00
0.60
0.42
10
25
A
GLN
0.91
0.43
0.64
10
26
A
ARG
0.42
0.51
0.70
10
27
A
GLY
0.83
0.41
0.65
10
28
A
ASP
0.67
0.32
0.48
9
29
A
THR
0.60
0.33
0.49
10
30
A
HIS
0.70
0.60
0.53
10
31
A
PRO
0.82
0.47
0.45
10
32
A
LEU
1.00
0.70
0.37
10
34
A
LEU
0.65
0.70
0.26
10
36
A
GLU
0.94
0.33
0.49
10
39
A
ASP
0.86
0.32
0.54
10
40
A
GLU
0.94
0.33
0.49
10
42
A
GLN
0.62
0.43
0.58
10
44
A
LEU
0.76
0.70
0.59
10
45
A
ASP
1.00
0.32
0.63
10
46
A
ILE
0.63
0.64
0.38
10
47
A
GLY
0.59
0.41
0.50
10
48
A
LEU
0.42
0.70
0.63
8
49
A
LYS
0.43
0.25
0.55
6
52
A
GLN
0.49
0.43
0.54
8
53
A
TRP
0.96
0.99
0.35
10
55
A
MET
0.50
0.66
0.43
8
56
A
THR
0.23
0.33
0.56
8
57
A
GLU
1.00
0.33
0.51
8
58
A
ALA
0.91
0.38
0.29
7
60
A
VAL
0.52
0.56
0.47
10
61
A
ASN
0.28
0.39
0.53
10
62
A
ASN
1.00
0.39
0.31
9
63
A
PRO
0.97
0.47
0.49
10
64
A
LYS
0.88
0.25
0.40
8
67
A
VAL
0.36
0.56
0.42
2
68
A
ILE
0.30
0.64
0.50
2
69
A
ASP
0.41
0.32
0.66
2
74
A
PHE
0.84
1.00
0.25
10
76
A
PRO
0.84
0.47
0.46
9
77
A
LYS
0.61
0.25
0.63
8
78
A
TYR
0.85
0.80
0.67
8
79
A
ASN
0.58
0.39
0.59
8
80
A
VAL
0.62
0.56
0.75
6
81
A
ARG
0.53
0.51
0.67
6
7
A
GLY
0.59
0.41
0.52
10
8
A
TYR
0.59
0.80
0.47
10
10
A
PHE
1.00
1.00
0.48
10
11
A
GLY
0.65
0.41
0.45
10
12
A
VAL
0.61
0.56
0.28
10
13
A
LEU
0.90
0.70
0.19
10
14
A
ALA
0.81
0.38
0.38
10
15
A
LYS
0.79
0.25
0.44
10
17
A
VAL
0.98
0.56
0.17
8
18
A
ASN
0.63
0.39
0.44
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.42
4
22
A
THR
0.62
0.33
0.52
10
23
A
ARG
0.90
0.51
0.46
10
24
A
HIS
1.00
0.60
0.42
10
25
A
GLN
0.91
0.43
0.59
10
26
A
ARG
0.42
0.51
0.70
10
27
A
GLY
0.83
0.41
0.66
10
28
A
ASP
0.67
0.32
0.56
10
29
A
THR
0.60
0.33
0.54
10
30
A
HIS
0.70
0.60
0.54
10
31
A
PRO
0.82
0.47
0.49
10
32
A
LEU
1.00
0.70
0.36
10
34
A
LEU
0.65
0.70
0.24
10
35
A
ASP
0.24
0.32
0.51
10
36
A
GLU
0.94
0.33
0.48
10
39
A
ASP
0.86
0.32
0.54
10
40
A
GLU
0.94
0.33
0.48
10
42
A
GLN
0.62
0.43
0.60
10
43
A
HIS
0.59
0.60
0.39
10
44
A
LEU
0.76
0.70
0.59
10
45
A
ASP
1.00
0.32
0.67
10
46
A
ILE
0.63
0.64
0.40
10
47
A
GLY
0.59
0.41
0.55
10
48
A
LEU
0.42
0.70
0.66
9
49
A
LYS
0.43
0.25
0.58
9
50
A
GLN
0.55
0.43
0.38
9
52
A
GLN
0.49
0.43
0.57
10
53
A
TRP
0.96
0.99
0.39
10
55
A
MET
0.50
0.66
0.43
10
56
A
THR
0.23
0.33
0.57
10
57
A
GLU
1.00
0.33
0.54
10
58
A
ALA
0.91
0.38
0.31
9
60
A
VAL
0.52
0.56
0.49
10
61
A
ASN
0.28
0.39
0.52
10
62
A
ASN
1.00
0.39
0.27
7
63
A
PRO
0.97
0.47
0.42
10
64
A
LYS
0.88
0.25
0.33
6
67
A
VAL
0.36
0.56
0.48
7
68
A
ILE
0.30
0.64
0.58
4
69
A
ASP
0.41
0.32
0.70
4
70
A
GLY
0.63
0.41
0.59
1
71
A
LYS
0.65
0.25
0.56
1
72
A
TYR
0.60
0.80
0.24
10
74
A
PHE
0.84
1.00
0.24
10
75
A
LYS
0.78
0.25
0.41
3
76
A
PRO
0.84
0.47
0.46
10
77
A
LYS
0.61
0.25
0.52
1
78
A
TYR
0.85
0.80
0.57
10
79
A
ASN
0.58
0.39
0.59
8
80
A
VAL
0.62
0.56
0.68
8
81
A
ARG
0.53
0.51
0.78
2
3
A
SER
0.40
0.36
0.66
1
4
A
GLY
0.56
0.41
0.73
1
5
A
SER
0.69
0.36
0.70
2
6
A
SER
0.66
0.36
0.70
3
7
A
GLY
0.59
0.41
0.62
8
8
A
TYR
0.59
0.80
0.63
8
10
A
PHE
1.00
1.00
0.57
8
11
A
GLY
0.65
0.41
0.47
5
12
A
VAL
0.61
0.56
0.31
9
13
A
LEU
0.90
0.70
0.24
8
14
A
ALA
0.81
0.38
0.37
1
17
A
VAL
0.98
0.56
0.17
6
19
A
TYR
0.66
0.80
0.27
10
23
A
ARG
0.90
0.51
0.44
10
24
A
HIS
1.00
0.60
0.41
10
25
A
GLN
0.91
0.43
0.52
10
26
A
ARG
0.42
0.51
0.62
10
27
A
GLY
0.83
0.41
0.65
10
28
A
ASP
0.67
0.32
0.56
10
29
A
THR
0.60
0.33
0.53
10
30
A
HIS
0.70
0.60
0.56
10
31
A
PRO
0.82
0.47
0.48
10
32
A
LEU
1.00
0.70
0.38
10
34
A
LEU
0.65
0.70
0.26
10
36
A
GLU
0.94
0.33
0.50
10
39
A
ASP
0.86
0.32
0.57
10
40
A
GLU
0.94
0.33
0.50
10
41
A
THR
0.84
0.33
0.33
9
42
A
GLN
0.62
0.43
0.59
10
43
A
HIS
0.59
0.60
0.40
10
44
A
LEU
0.76
0.70
0.62
10
45
A
ASP
1.00
0.32
0.67
10
46
A
ILE
0.63
0.64
0.43
10
47
A
GLY
0.59
0.41
0.59
10
48
A
LEU
0.42
0.70
0.69
8
49
A
LYS
0.43
0.25
0.68
8
50
A
GLN
0.55
0.43
0.46
8
51
A
LYS
0.69
0.25
0.47
1
52
A
GLN
0.49
0.43
0.59
8
53
A
TRP
0.96
0.99
0.44
8
55
A
MET
0.50
0.66
0.48
8
56
A
THR
0.23
0.33
0.60
8
57
A
GLU
1.00
0.33
0.56
8
60
A
VAL
0.52
0.56
0.54
8
61
A
ASN
0.28
0.39
0.60
8
62
A
ASN
1.00
0.39
0.41
8
63
A
PRO
0.97
0.47
0.56
8
64
A
LYS
0.88
0.25
0.41
8
65
A
ILE
0.82
0.64
0.23
7
67
A
VAL
0.36
0.56
0.54
3
68
A
ILE
0.30
0.64
0.62
3
69
A
ASP
0.41
0.32
0.72
3
70
A
GLY
0.63
0.41
0.61
1
71
A
LYS
0.65
0.25
0.56
9
72
A
TYR
0.60
0.80
0.31
10
75
A
LYS
0.78
0.25
0.51
6
76
A
PRO
0.84
0.47
0.51
10
77
A
LYS
0.61
0.25
0.62
8
78
A
TYR
0.85
0.80
0.70
9
79
A
ASN
0.58
0.39
0.55
10
80
A
VAL
0.62
0.56
0.70
10
81
A
ARG
0.53
0.51
0.74
10
7
A
GLY
0.59
0.41
0.49
10
8
A
TYR
0.59
0.80
0.49
10
10
A
PHE
1.00
1.00
0.49
10
11
A
GLY
0.65
0.41
0.42
10
12
A
VAL
0.61
0.56
0.27
10
13
A
LEU
0.90
0.70
0.24
10
14
A
ALA
0.81
0.38
0.41
10
15
A
LYS
0.79
0.25
0.41
10
17
A
VAL
0.98
0.56
0.24
10
18
A
ASN
0.63
0.39
0.47
10
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.48
9
22
A
THR
0.62
0.33
0.54
10
23
A
ARG
0.90
0.51
0.47
10
24
A
HIS
1.00
0.60
0.39
10
25
A
GLN
0.91
0.43
0.60
10
26
A
ARG
0.42
0.51
0.68
10
27
A
GLY
0.83
0.41
0.66
10
28
A
ASP
0.67
0.32
0.55
10
29
A
THR
0.60
0.33
0.48
10
30
A
HIS
0.70
0.60
0.52
10
31
A
PRO
0.82
0.47
0.42
10
32
A
LEU
1.00
0.70
0.35
10
33
A
THR
0.62
0.33
0.46
1
34
A
LEU
0.65
0.70
0.29
10
35
A
ASP
0.24
0.32
0.50
10
36
A
GLU
0.94
0.33
0.48
10
39
A
ASP
0.86
0.32
0.55
10
40
A
GLU
0.94
0.33
0.48
10
42
A
GLN
0.62
0.43
0.58
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.66
10
46
A
ILE
0.63
0.64
0.42
10
47
A
GLY
0.59
0.41
0.53
10
48
A
LEU
0.42
0.70
0.67
10
49
A
LYS
0.43
0.25
0.63
10
50
A
GLN
0.55
0.43
0.38
10
51
A
LYS
0.69
0.25
0.44
1
52
A
GLN
0.49
0.43
0.55
10
53
A
TRP
0.96
0.99
0.40
10
55
A
MET
0.50
0.66
0.41
10
56
A
THR
0.23
0.33
0.55
10
57
A
GLU
1.00
0.33
0.52
10
58
A
ALA
0.91
0.38
0.29
6
60
A
VAL
0.52
0.56
0.46
10
61
A
ASN
0.28
0.39
0.54
10
62
A
ASN
1.00
0.39
0.35
10
63
A
PRO
0.97
0.47
0.51
10
64
A
LYS
0.88
0.25
0.42
10
68
A
ILE
0.30
0.64
0.49
1
69
A
ASP
0.41
0.32
0.64
1
70
A
GLY
0.63
0.41
0.56
1
72
A
TYR
0.60
0.80
0.20
10
74
A
PHE
0.84
1.00
0.24
10
76
A
PRO
0.84
0.47
0.44
10
77
A
LYS
0.61
0.25
0.61
6
78
A
TYR
0.85
0.80
0.64
6
79
A
ASN
0.58
0.39
0.56
6
80
A
VAL
0.62
0.56
0.67
2
3
A
SER
0.40
0.36
0.76
7
4
A
GLY
0.56
0.41
0.66
8
5
A
SER
0.69
0.36
0.67
9
6
A
SER
0.66
0.36
0.66
9
7
A
GLY
0.59
0.41
0.56
9
8
A
TYR
0.59
0.80
0.55
9
10
A
PHE
1.00
1.00
0.54
10
12
A
VAL
0.61
0.56
0.25
10
13
A
LEU
0.90
0.70
0.24
10
14
A
ALA
0.81
0.38
0.38
3
15
A
LYS
0.79
0.25
0.41
8
17
A
VAL
0.98
0.56
0.23
10
18
A
ASN
0.63
0.39
0.44
10
19
A
TYR
0.66
0.80
0.30
10
21
A
LYS
0.72
0.25
0.44
6
22
A
THR
0.62
0.33
0.52
10
23
A
ARG
0.90
0.51
0.45
10
24
A
HIS
1.00
0.60
0.35
10
25
A
GLN
0.91
0.43
0.55
10
26
A
ARG
0.42
0.51
0.67
10
27
A
GLY
0.83
0.41
0.61
10
28
A
ASP
0.67
0.32
0.55
10
29
A
THR
0.60
0.33
0.47
1
30
A
HIS
0.70
0.60
0.51
10
31
A
PRO
0.82
0.47
0.46
10
32
A
LEU
1.00
0.70
0.35
10
34
A
LEU
0.65
0.70
0.28
10
35
A
ASP
0.24
0.32
0.52
10
36
A
GLU
0.94
0.33
0.49
10
39
A
ASP
0.86
0.32
0.55
10
40
A
GLU
0.94
0.33
0.48
10
41
A
THR
0.84
0.33
0.31
6
42
A
GLN
0.62
0.43
0.56
10
43
A
HIS
0.59
0.60
0.35
10
44
A
LEU
0.76
0.70
0.59
10
45
A
ASP
1.00
0.32
0.65
10
46
A
ILE
0.63
0.64
0.41
10
47
A
GLY
0.59
0.41
0.55
10
48
A
LEU
0.42
0.70
0.67
9
49
A
LYS
0.43
0.25
0.67
9
50
A
GLN
0.55
0.43
0.42
9
52
A
GLN
0.49
0.43
0.59
10
53
A
TRP
0.96
0.99
0.44
10
55
A
MET
0.50
0.66
0.46
10
56
A
THR
0.23
0.33
0.59
10
57
A
GLU
1.00
0.33
0.57
10
58
A
ALA
0.91
0.38
0.36
8
60
A
VAL
0.52
0.56
0.51
10
61
A
ASN
0.28
0.39
0.58
10
62
A
ASN
1.00
0.39
0.38
10
63
A
PRO
0.97
0.47
0.54
10
64
A
LYS
0.88
0.25
0.41
10
68
A
ILE
0.30
0.64
0.56
2
69
A
ASP
0.41
0.32
0.68
2
71
A
LYS
0.65
0.25
0.56
10
72
A
TYR
0.60
0.80
0.28
10
75
A
LYS
0.78
0.25
0.45
7
76
A
PRO
0.84
0.47
0.45
10
77
A
LYS
0.61
0.25
0.63
10
78
A
TYR
0.85
0.80
0.72
10
79
A
ASN
0.58
0.39
0.69
10
80
A
VAL
0.62
0.56
0.61
10
81
A
ARG
0.53
0.51
0.72
3
6
A
SER
0.66
0.36
0.64
9
7
A
GLY
0.59
0.41
0.56
9
8
A
TYR
0.59
0.80
0.59
9
10
A
PHE
1.00
1.00
0.53
9
11
A
GLY
0.65
0.41
0.42
5
12
A
VAL
0.61
0.56
0.28
8
13
A
LEU
0.90
0.70
0.24
9
14
A
ALA
0.81
0.38
0.35
6
15
A
LYS
0.79
0.25
0.40
8
17
A
VAL
0.98
0.56
0.20
7
18
A
ASN
0.63
0.39
0.39
3
19
A
TYR
0.66
0.80
0.33
10
21
A
LYS
0.72
0.25
0.44
1
22
A
THR
0.62
0.33
0.52
8
23
A
ARG
0.90
0.51
0.46
10
24
A
HIS
1.00
0.60
0.42
10
25
A
GLN
0.91
0.43
0.59
10
26
A
ARG
0.42
0.51
0.68
10
27
A
GLY
0.83
0.41
0.67
10
28
A
ASP
0.67
0.32
0.59
10
29
A
THR
0.60
0.33
0.54
8
30
A
HIS
0.70
0.60
0.56
10
31
A
PRO
0.82
0.47
0.48
10
32
A
LEU
1.00
0.70
0.40
10
34
A
LEU
0.65
0.70
0.30
10
35
A
ASP
0.24
0.32
0.53
7
36
A
GLU
0.94
0.33
0.52
9
39
A
ASP
0.86
0.32
0.58
10
40
A
GLU
0.94
0.33
0.52
9
42
A
GLN
0.62
0.43
0.57
10
43
A
HIS
0.59
0.60
0.41
10
44
A
LEU
0.76
0.70
0.62
10
45
A
ASP
1.00
0.32
0.68
10
46
A
ILE
0.63
0.64
0.46
10
47
A
GLY
0.59
0.41
0.58
10
48
A
LEU
0.42
0.70
0.71
10
49
A
LYS
0.43
0.25
0.66
8
50
A
GLN
0.55
0.43
0.46
8
52
A
GLN
0.49
0.43
0.59
9
53
A
TRP
0.96
0.99
0.44
9
55
A
MET
0.50
0.66
0.47
9
56
A
THR
0.23
0.33
0.59
9
57
A
GLU
1.00
0.33
0.55
9
60
A
VAL
0.52
0.56
0.51
9
61
A
ASN
0.28
0.39
0.54
9
62
A
ASN
1.00
0.39
0.37
9
63
A
PRO
0.97
0.47
0.53
9
64
A
LYS
0.88
0.25
0.40
5
67
A
VAL
0.36
0.56
0.52
3
68
A
ILE
0.30
0.64
0.61
3
69
A
ASP
0.41
0.32
0.72
3
70
A
GLY
0.63
0.41
0.62
1
71
A
LYS
0.65
0.25
0.57
4
74
A
PHE
0.84
1.00
0.27
10
75
A
LYS
0.78
0.25
0.48
3
76
A
PRO
0.84
0.47
0.51
10
77
A
LYS
0.61
0.25
0.58
1
78
A
TYR
0.85
0.80
0.72
6
79
A
ASN
0.58
0.39
0.76
5
80
A
VAL
0.62
0.56
0.70
5
81
A
ARG
0.53
0.51
0.64
10
7
A
GLY
0.59
0.41
0.53
10
8
A
TYR
0.59
0.80
0.53
10
9
A
LYS
0.51
0.25
0.49
9
10
A
PHE
1.00
1.00
0.52
10
11
A
GLY
0.65
0.41
0.40
10
12
A
VAL
0.61
0.56
0.25
10
13
A
LEU
0.90
0.70
0.23
10
14
A
ALA
0.81
0.38
0.35
9
15
A
LYS
0.79
0.25
0.38
7
17
A
VAL
0.98
0.56
0.17
7
18
A
ASN
0.63
0.39
0.41
8
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.38
1
23
A
ARG
0.90
0.51
0.46
10
24
A
HIS
1.00
0.60
0.39
10
25
A
GLN
0.91
0.43
0.54
10
26
A
ARG
0.42
0.51
0.65
10
27
A
GLY
0.83
0.41
0.65
10
28
A
ASP
0.67
0.32
0.55
10
29
A
THR
0.60
0.33
0.52
10
30
A
HIS
0.70
0.60
0.56
10
31
A
PRO
0.82
0.47
0.46
10
32
A
LEU
1.00
0.70
0.39
10
34
A
LEU
0.65
0.70
0.27
10
35
A
ASP
0.24
0.32
0.51
9
36
A
GLU
0.94
0.33
0.50
10
39
A
ASP
0.86
0.32
0.56
10
40
A
GLU
0.94
0.33
0.49
10
41
A
THR
0.84
0.33
0.35
10
42
A
GLN
0.62
0.43
0.58
10
43
A
HIS
0.59
0.60
0.37
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.65
10
46
A
ILE
0.63
0.64
0.42
10
47
A
GLY
0.59
0.41
0.56
10
48
A
LEU
0.42
0.70
0.69
9
49
A
LYS
0.43
0.25
0.65
9
50
A
GLN
0.55
0.43
0.44
9
52
A
GLN
0.49
0.43
0.58
10
53
A
TRP
0.96
0.99
0.43
10
55
A
MET
0.50
0.66
0.46
10
56
A
THR
0.23
0.33
0.56
10
57
A
GLU
1.00
0.33
0.55
10
60
A
VAL
0.52
0.56
0.49
10
61
A
ASN
0.28
0.39
0.54
10
62
A
ASN
1.00
0.39
0.37
10
63
A
PRO
0.97
0.47
0.53
10
64
A
LYS
0.88
0.25
0.39
9
67
A
VAL
0.36
0.56
0.49
3
68
A
ILE
0.30
0.64
0.60
3
69
A
ASP
0.41
0.32
0.71
3
70
A
GLY
0.63
0.41
0.58
1
71
A
LYS
0.65
0.25
0.56
1
75
A
LYS
0.78
0.25
0.48
6
76
A
PRO
0.84
0.47
0.51
10
77
A
LYS
0.61
0.25
0.58
10
78
A
TYR
0.85
0.80
0.66
10
79
A
ASN
0.58
0.39
0.57
10
80
A
VAL
0.62
0.56
0.71
10
81
A
ARG
0.53
0.51
0.73
10
1
A
ALA
0.16
0.38
0.63
6
2
A
LEU
0.41
0.70
0.75
2
3
A
SER
0.40
0.36
0.67
2
4
A
GLY
0.56
0.41
0.55
6
5
A
SER
0.69
0.36
0.65
6
6
A
SER
0.66
0.36
0.64
6
7
A
GLY
0.59
0.41
0.62
6
8
A
TYR
0.59
0.80
0.61
6
10
A
PHE
1.00
1.00
0.52
9
11
A
GLY
0.65
0.41
0.46
9
12
A
VAL
0.61
0.56
0.34
10
13
A
LEU
0.90
0.70
0.20
10
15
A
LYS
0.79
0.25
0.43
8
17
A
VAL
0.98
0.56
0.15
8
18
A
ASN
0.63
0.39
0.38
1
19
A
TYR
0.66
0.80
0.30
10
21
A
LYS
0.72
0.25
0.38
3
22
A
THR
0.62
0.33
0.49
10
23
A
ARG
0.90
0.51
0.41
10
24
A
HIS
1.00
0.60
0.43
10
25
A
GLN
0.91
0.43
0.57
10
26
A
ARG
0.42
0.51
0.68
10
27
A
GLY
0.83
0.41
0.69
10
28
A
ASP
0.67
0.32
0.57
10
29
A
THR
0.60
0.33
0.58
10
30
A
HIS
0.70
0.60
0.55
10
31
A
PRO
0.82
0.47
0.51
10
32
A
LEU
1.00
0.70
0.39
10
33
A
THR
0.62
0.33
0.49
9
34
A
LEU
0.65
0.70
0.27
10
35
A
ASP
0.24
0.32
0.50
10
36
A
GLU
0.94
0.33
0.50
10
39
A
ASP
0.86
0.32
0.56
10
40
A
GLU
0.94
0.33
0.51
10
42
A
GLN
0.62
0.43
0.62
10
43
A
HIS
0.59
0.60
0.41
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.68
10
46
A
ILE
0.63
0.64
0.43
10
47
A
GLY
0.59
0.41
0.59
10
48
A
LEU
0.42
0.70
0.69
9
49
A
LYS
0.43
0.25
0.69
9
52
A
GLN
0.49
0.43
0.59
10
53
A
TRP
0.96
0.99
0.41
10
55
A
MET
0.50
0.66
0.46
10
56
A
THR
0.23
0.33
0.58
10
57
A
GLU
1.00
0.33
0.52
10
58
A
ALA
0.91
0.38
0.30
7
60
A
VAL
0.52
0.56
0.51
10
61
A
ASN
0.28
0.39
0.55
10
62
A
ASN
1.00
0.39
0.32
10
63
A
PRO
0.97
0.47
0.46
10
64
A
LYS
0.88
0.25
0.33
9
67
A
VAL
0.36
0.56
0.54
1
68
A
ILE
0.30
0.64
0.60
3
69
A
ASP
0.41
0.32
0.72
3
70
A
GLY
0.63
0.41
0.62
1
71
A
LYS
0.65
0.25
0.58
9
75
A
LYS
0.78
0.25
0.49
8
76
A
PRO
0.84
0.47
0.51
10
78
A
TYR
0.85
0.80
0.62
10
79
A
ASN
0.58
0.39
0.69
10
80
A
VAL
0.62
0.56
0.68
10
81
A
ARG
0.53
0.51
0.74
4
7
A
GLY
0.59
0.41
0.52
6
8
A
TYR
0.59
0.80
0.54
6
10
A
PHE
1.00
1.00
0.48
9
11
A
GLY
0.65
0.41
0.43
7
12
A
VAL
0.61
0.56
0.30
10
13
A
LEU
0.90
0.70
0.24
10
14
A
ALA
0.81
0.38
0.38
10
15
A
LYS
0.79
0.25
0.44
6
17
A
VAL
0.98
0.56
0.22
10
18
A
ASN
0.63
0.39
0.44
10
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.43
4
22
A
THR
0.62
0.33
0.52
10
23
A
ARG
0.90
0.51
0.44
10
24
A
HIS
1.00
0.60
0.36
10
25
A
GLN
0.91
0.43
0.57
10
26
A
ARG
0.42
0.51
0.65
10
27
A
GLY
0.83
0.41
0.62
10
28
A
ASP
0.67
0.32
0.52
10
29
A
THR
0.60
0.33
0.47
3
30
A
HIS
0.70
0.60
0.53
10
31
A
PRO
0.82
0.47
0.46
7
34
A
LEU
0.65
0.70
0.29
10
35
A
ASP
0.24
0.32
0.52
10
36
A
GLU
0.94
0.33
0.51
9
39
A
ASP
0.86
0.32
0.57
10
40
A
GLU
0.94
0.33
0.52
10
41
A
THR
0.84
0.33
0.40
10
42
A
GLN
0.62
0.43
0.61
10
43
A
HIS
0.59
0.60
0.44
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.66
10
46
A
ILE
0.63
0.64
0.45
10
47
A
GLY
0.59
0.41
0.60
10
48
A
LEU
0.42
0.70
0.69
10
49
A
LYS
0.43
0.25
0.63
8
50
A
GLN
0.55
0.43
0.40
7
51
A
LYS
0.69
0.25
0.48
3
52
A
GLN
0.49
0.43
0.59
10
53
A
TRP
0.96
0.99
0.43
10
55
A
MET
0.50
0.66
0.44
10
56
A
THR
0.23
0.33
0.59
10
57
A
GLU
1.00
0.33
0.56
10
58
A
ALA
0.91
0.38
0.35
7
60
A
VAL
0.52
0.56
0.51
10
61
A
ASN
0.28
0.39
0.59
10
62
A
ASN
1.00
0.39
0.37
10
63
A
PRO
0.97
0.47
0.54
10
64
A
LYS
0.88
0.25
0.43
10
67
A
VAL
0.36
0.56
0.52
1
68
A
ILE
0.30
0.64
0.55
2
69
A
ASP
0.41
0.32
0.70
2
70
A
GLY
0.63
0.41
0.61
1
71
A
LYS
0.65
0.25
0.57
9
72
A
TYR
0.60
0.80
0.27
7
75
A
LYS
0.78
0.25
0.48
8
76
A
PRO
0.84
0.47
0.46
10
77
A
LYS
0.61
0.25
0.64
10
78
A
TYR
0.85
0.80
0.60
10
79
A
ASN
0.58
0.39
0.78
9
80
A
VAL
0.62
0.56
0.73
9
81
A
ARG
0.53
0.51
0.66
10
1
A
ALA
0.16
0.38
0.60
7
2
A
LEU
0.41
0.70
0.74
7
3
A
SER
0.40
0.36
0.73
2
4
A
GLY
0.56
0.41
0.79
3
5
A
SER
0.69
0.36
0.74
3
6
A
SER
0.66
0.36
0.60
7
7
A
GLY
0.59
0.41
0.58
7
8
A
TYR
0.59
0.80
0.50
8
10
A
PHE
1.00
1.00
0.49
10
11
A
GLY
0.65
0.41
0.46
10
12
A
VAL
0.61
0.56
0.26
10
13
A
LEU
0.90
0.70
0.20
10
14
A
ALA
0.81
0.38
0.39
10
15
A
LYS
0.79
0.25
0.45
10
17
A
VAL
0.98
0.56
0.21
10
18
A
ASN
0.63
0.39
0.42
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.38
4
22
A
THR
0.62
0.33
0.48
10
23
A
ARG
0.90
0.51
0.48
10
24
A
HIS
1.00
0.60
0.35
10
25
A
GLN
0.91
0.43
0.51
10
26
A
ARG
0.42
0.51
0.64
10
27
A
GLY
0.83
0.41
0.61
10
28
A
ASP
0.67
0.32
0.51
10
29
A
THR
0.60
0.33
0.48
10
30
A
HIS
0.70
0.60
0.54
10
31
A
PRO
0.82
0.47
0.50
10
34
A
LEU
0.65
0.70
0.25
10
36
A
GLU
0.94
0.33
0.47
10
39
A
ASP
0.86
0.32
0.54
10
40
A
GLU
0.94
0.33
0.48
10
42
A
GLN
0.62
0.43
0.60
10
43
A
HIS
0.59
0.60
0.39
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.68
10
46
A
ILE
0.63
0.64
0.41
10
47
A
GLY
0.59
0.41
0.54
10
48
A
LEU
0.42
0.70
0.66
7
49
A
LYS
0.43
0.25
0.60
7
50
A
GLN
0.55
0.43
0.38
7
52
A
GLN
0.49
0.43
0.54
10
53
A
TRP
0.96
0.99
0.34
10
55
A
MET
0.50
0.66
0.42
10
56
A
THR
0.23
0.33
0.55
10
57
A
GLU
1.00
0.33
0.49
10
58
A
ALA
0.91
0.38
0.27
7
60
A
VAL
0.52
0.56
0.48
10
61
A
ASN
0.28
0.39
0.54
10
62
A
ASN
1.00
0.39
0.34
10
63
A
PRO
0.97
0.47
0.50
10
64
A
LYS
0.88
0.25
0.39
10
68
A
ILE
0.30
0.64
0.57
2
69
A
ASP
0.41
0.32
0.71
2
74
A
PHE
0.84
1.00
0.22
10
75
A
LYS
0.78
0.25
0.46
6
76
A
PRO
0.84
0.47
0.45
10
78
A
TYR
0.85
0.80
0.68
4
79
A
ASN
0.58
0.39
0.61
4
80
A
VAL
0.62
0.56
0.74
3
81
A
ARG
0.53
0.51
0.69
3
3
A
SER
0.40
0.36
0.69
1
4
A
GLY
0.56
0.41
0.61
3
5
A
SER
0.69
0.36
0.65
3
6
A
SER
0.66
0.36
0.66
3
7
A
GLY
0.59
0.41
0.58
3
8
A
TYR
0.59
0.80
0.54
3
10
A
PHE
1.00
1.00
0.44
10
11
A
GLY
0.65
0.41
0.44
10
12
A
VAL
0.61
0.56
0.30
10
13
A
LEU
0.90
0.70
0.15
10
14
A
ALA
0.81
0.38
0.35
10
15
A
LYS
0.79
0.25
0.44
8
17
A
VAL
0.98
0.56
0.17
10
18
A
ASN
0.63
0.39
0.42
10
19
A
TYR
0.66
0.80
0.28
10
21
A
LYS
0.72
0.25
0.38
5
22
A
THR
0.62
0.33
0.48
10
23
A
ARG
0.90
0.51
0.38
10
24
A
HIS
1.00
0.60
0.31
10
25
A
GLN
0.91
0.43
0.52
10
26
A
ARG
0.42
0.51
0.63
10
27
A
GLY
0.83
0.41
0.59
10
28
A
ASP
0.67
0.32
0.51
10
29
A
THR
0.60
0.33
0.47
10
30
A
HIS
0.70
0.60
0.50
10
31
A
PRO
0.82
0.47
0.45
10
32
A
LEU
1.00
0.70
0.36
10
34
A
LEU
0.65
0.70
0.22
10
36
A
GLU
0.94
0.33
0.48
10
39
A
ASP
0.86
0.32
0.55
10
40
A
GLU
0.94
0.33
0.48
10
41
A
THR
0.84
0.33
0.35
10
42
A
GLN
0.62
0.43
0.62
10
43
A
HIS
0.59
0.60
0.40
10
44
A
LEU
0.76
0.70
0.60
10
45
A
ASP
1.00
0.32
0.66
10
46
A
ILE
0.63
0.64
0.38
10
47
A
GLY
0.59
0.41
0.54
10
48
A
LEU
0.42
0.70
0.65
8
49
A
LYS
0.43
0.25
0.63
8
50
A
GLN
0.55
0.43
0.38
8
52
A
GLN
0.49
0.43
0.53
10
53
A
TRP
0.96
0.99
0.33
10
55
A
MET
0.50
0.66
0.43
10
56
A
THR
0.23
0.33
0.56
10
57
A
GLU
1.00
0.33
0.50
10
58
A
ALA
0.91
0.38
0.26
8
60
A
VAL
0.52
0.56
0.51
10
61
A
ASN
0.28
0.39
0.52
10
62
A
ASN
1.00
0.39
0.30
10
63
A
PRO
0.97
0.47
0.47
10
64
A
LYS
0.88
0.25
0.33
10
67
A
VAL
0.36
0.56
0.51
2
68
A
ILE
0.30
0.64
0.56
3
69
A
ASP
0.41
0.32
0.71
3
70
A
GLY
0.63
0.41
0.60
2
71
A
LYS
0.65
0.25
0.54
2
74
A
PHE
0.84
1.00
0.17
10
75
A
LYS
0.78
0.25
0.42
4
76
A
PRO
0.84
0.47
0.41
1
77
A
LYS
0.61
0.25
0.56
1
78
A
TYR
0.85
0.80
0.64
1
79
A
ASN
0.58
0.39
0.53
10
2
A
LEU
0.41
0.70
0.67
3
3
A
SER
0.40
0.36
0.57
10
4
A
GLY
0.56
0.41
0.69
9
5
A
SER
0.69
0.36
0.65
9
6
A
SER
0.66
0.36
0.72
9
7
A
GLY
0.59
0.41
0.65
9
8
A
TYR
0.59
0.80
0.54
10
10
A
PHE
1.00
1.00
0.48
10
11
A
GLY
0.65
0.41
0.49
10
12
A
VAL
0.61
0.56
0.33
10
13
A
LEU
0.90
0.70
0.16
10
14
A
ALA
0.81
0.38
0.39
10
15
A
LYS
0.79
0.25
0.46
10
17
A
VAL
0.98
0.56
0.19
10
18
A
ASN
0.63
0.39
0.43
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.41
6
22
A
THR
0.62
0.33
0.48
10
23
A
ARG
0.90
0.51
0.42
10
24
A
HIS
1.00
0.60
0.31
10
25
A
GLN
0.91
0.43
0.49
10
26
A
ARG
0.42
0.51
0.64
10
27
A
GLY
0.83
0.41
0.56
10
28
A
ASP
0.67
0.32
0.50
10
29
A
THR
0.60
0.33
0.44
10
30
A
HIS
0.70
0.60
0.51
10
31
A
PRO
0.82
0.47
0.46
10
34
A
LEU
0.65
0.70
0.23
10
36
A
GLU
0.94
0.33
0.47
10
39
A
ASP
0.86
0.32
0.52
10
40
A
GLU
0.94
0.33
0.49
10
42
A
GLN
0.62
0.43
0.60
10
43
A
HIS
0.59
0.60
0.39
10
44
A
LEU
0.76
0.70
0.59
10
45
A
ASP
1.00
0.32
0.67
10
46
A
ILE
0.63
0.64
0.39
10
47
A
GLY
0.59
0.41
0.53
10
48
A
LEU
0.42
0.70
0.63
7
49
A
LYS
0.43
0.25
0.61
7
50
A
GLN
0.55
0.43
0.35
7
52
A
GLN
0.49
0.43
0.53
10
53
A
TRP
0.96
0.99
0.31
10
55
A
MET
0.50
0.66
0.39
10
56
A
THR
0.23
0.33
0.51
10
57
A
GLU
1.00
0.33
0.44
10
58
A
ALA
0.91
0.38
0.21
3
60
A
VAL
0.52
0.56
0.45
10
61
A
ASN
0.28
0.39
0.49
10
62
A
ASN
1.00
0.39
0.31
10
63
A
PRO
0.97
0.47
0.48
10
64
A
LYS
0.88
0.25
0.40
10
68
A
ILE
0.30
0.64
0.53
1
69
A
ASP
0.41
0.32
0.69
1
72
A
TYR
0.60
0.80
0.23
1
74
A
PHE
0.84
1.00
0.20
10
75
A
LYS
0.78
0.25
0.41
5
76
A
PRO
0.84
0.47
0.40
1
77
A
LYS
0.61
0.25
0.56
6
78
A
TYR
0.85
0.80
0.57
6
79
A
ASN
0.58
0.39
0.63
2
80
A
VAL
0.62
0.56
0.63
1
81
A
ARG
0.53
0.51
0.77
1
1
A
ALA
0.16
0.38
0.68
8
4
A
GLY
0.56
0.41
0.68
8
5
A
SER
0.69
0.36
0.59
8
6
A
SER
0.66
0.36
0.62
10
7
A
GLY
0.59
0.41
0.60
10
8
A
TYR
0.59
0.80
0.59
10
10
A
PHE
1.00
1.00
0.56
10
13
A
LEU
0.90
0.70
0.26
10
14
A
ALA
0.81
0.38
0.39
6
15
A
LYS
0.79
0.25
0.40
8
17
A
VAL
0.98
0.56
0.22
10
18
A
ASN
0.63
0.39
0.41
10
19
A
TYR
0.66
0.80
0.29
10
21
A
LYS
0.72
0.25
0.41
3
22
A
THR
0.62
0.33
0.49
10
23
A
ARG
0.90
0.51
0.47
10
24
A
HIS
1.00
0.60
0.38
10
25
A
GLN
0.91
0.43
0.51
10
26
A
ARG
0.42
0.51
0.66
10
27
A
GLY
0.83
0.41
0.61
10
28
A
ASP
0.67
0.32
0.52
10
29
A
THR
0.60
0.33
0.50
10
30
A
HIS
0.70
0.60
0.55
10
31
A
PRO
0.82
0.47
0.51
10
32
A
LEU
1.00
0.70
0.40
10
33
A
THR
0.62
0.33
0.49
2
35
A
ASP
0.24
0.32
0.49
9
36
A
GLU
0.94
0.33
0.50
10
39
A
ASP
0.86
0.32
0.54
10
40
A
GLU
0.94
0.33
0.50
10
42
A
GLN
0.62
0.43
0.56
10
43
A
HIS
0.59
0.60
0.35
10
44
A
LEU
0.76
0.70
0.58
10
45
A
ASP
1.00
0.32
0.64
10
46
A
ILE
0.63
0.64
0.41
10
47
A
GLY
0.59
0.41
0.54
10
48
A
LEU
0.42
0.70
0.69
10
49
A
LYS
0.43
0.25
0.68
10
50
A
GLN
0.55
0.43
0.43
10
51
A
LYS
0.69
0.25
0.46
1
52
A
GLN
0.49
0.43
0.60
10
53
A
TRP
0.96
0.99
0.44
10
55
A
MET
0.50
0.66
0.45
10
56
A
THR
0.23
0.33
0.59
10
57
A
GLU
1.00
0.33
0.57
10
58
A
ALA
0.91
0.38
0.35
9
60
A
VAL
0.52
0.56
0.52
10
61
A
ASN
0.28
0.39
0.63
10
62
A
ASN
1.00
0.39
0.40
10
63
A
PRO
0.97
0.47
0.55
10
64
A
LYS
0.88
0.25
0.42
10
67
A
VAL
0.36
0.56
0.53
10
68
A
ILE
0.30
0.64
0.59
5
69
A
ASP
0.41
0.32
0.73
5
70
A
GLY
0.63
0.41
0.63
4
71
A
LYS
0.65
0.25
0.57
10
74
A
PHE
0.84
1.00
0.25
10
75
A
LYS
0.78
0.25
0.47
6
76
A
PRO
0.84
0.47
0.49
10
77
A
LYS
0.61
0.25
0.64
10
78
A
TYR
0.85
0.80
0.65
7
79
A
ASN
0.58
0.39
0.60
10
80
A
VAL
0.62
0.56
0.62
10
81
A
ARG
0.53
0.51
0.79
7
1
A
ALA
0.16
0.38
0.79
1
2
A
LEU
0.41
0.70
0.72
1
4
A
GLY
0.56
0.41
0.61
1
5
A
SER
0.69
0.36
0.58
5
6
A
SER
0.66
0.36
0.63
6
7
A
GLY
0.59
0.41
0.57
6
8
A
TYR
0.59
0.80
0.48
6
10
A
PHE
1.00
1.00
0.45
9
11
A
GLY
0.65
0.41
0.44
9
12
A
VAL
0.61
0.56
0.30
9
13
A
LEU
0.90
0.70
0.18
10
14
A
ALA
0.81
0.38
0.36
8
15
A
LYS
0.79
0.25
0.44
8
17
A
VAL
0.98
0.56
0.16
2
19
A
TYR
0.66
0.80
0.29
10
22
A
THR
0.62
0.33
0.48
8
23
A
ARG
0.90
0.51
0.46
10
24
A
HIS
1.00
0.60
0.43
10
25
A
GLN
0.91
0.43
0.59
10
26
A
ARG
0.42
0.51
0.66
10
27
A
GLY
0.83
0.41
0.66
10
28
A
ASP
0.67
0.32
0.55
10
29
A
THR
0.60
0.33
0.54
9
30
A
HIS
0.70
0.60
0.56
10
31
A
PRO
0.82
0.47
0.51
10
34
A
LEU
0.65
0.70
0.24
9
35
A
ASP
0.24
0.32
0.48
8
36
A
GLU
0.94
0.33
0.47
9
39
A
ASP
0.86
0.32
0.55
9
40
A
GLU
0.94
0.33
0.50
10
41
A
THR
0.84
0.33
0.34
9
42
A
GLN
0.62
0.43
0.61
9
43
A
HIS
0.59
0.60
0.41
9
44
A
LEU
0.76
0.70
0.61
9
45
A
ASP
1.00
0.32
0.68
9
46
A
ILE
0.63
0.64
0.39
9
47
A
GLY
0.59
0.41
0.54
9
48
A
LEU
0.42
0.70
0.65
7
49
A
LYS
0.43
0.25
0.56
7
50
A
GLN
0.55
0.43
0.34
7
52
A
GLN
0.49
0.43
0.55
7
53
A
TRP
0.96
0.99
0.34
6
55
A
MET
0.50
0.66
0.44
5
56
A
THR
0.23
0.33
0.56
5
57
A
GLU
1.00
0.33
0.49
5
58
A
ALA
0.91
0.38
0.28
1
60
A
VAL
0.52
0.56
0.49
10
61
A
ASN
0.28
0.39
0.54
10
62
A
ASN
1.00
0.39
0.35
10
63
A
PRO
0.97
0.47
0.52
10
64
A
LYS
0.88
0.25
0.37
7
67
A
VAL
0.36
0.56
0.51
1
68
A
ILE
0.30
0.64
0.60
3
69
A
ASP
0.41
0.32
0.71
3
70
A
GLY
0.63
0.41
0.60
1
71
A
LYS
0.65
0.25
0.54
9
75
A
LYS
0.78
0.25
0.50
9
76
A
PRO
0.84
0.47
0.54
10
77
A
LYS
0.61
0.25
0.66
10
78
A
TYR
0.85
0.80
0.62
10
79
A
ASN
0.58
0.39
0.57
10
80
A
VAL
0.62
0.56
0.71
10
81
A
ARG
0.53
0.51
0.61
10
4
A
GLY
0.56
0.41
0.63
6
5
A
SER
0.69
0.36
0.69
7
6
A
SER
0.66
0.36
0.62
9
7
A
GLY
0.59
0.41
0.53
5
8
A
TYR
0.59
0.80
0.57
9
10
A
PHE
1.00
1.00
0.48
10
11
A
GLY
0.65
0.41
0.41
9
12
A
VAL
0.61
0.56
0.26
10
13
A
LEU
0.90
0.70
0.18
10
14
A
ALA
0.81
0.38
0.34
4
15
A
LYS
0.79
0.25
0.39
10
17
A
VAL
0.98
0.56
0.17
5
18
A
ASN
0.63
0.39
0.42
8
19
A
TYR
0.66
0.80
0.31
10
21
A
LYS
0.72
0.25
0.43
3
22
A
THR
0.62
0.33
0.53
10
23
A
ARG
0.90
0.51
0.46
10
24
A
HIS
1.00
0.60
0.44
10
25
A
GLN
0.91
0.43
0.63
10
26
A
ARG
0.42
0.51
0.69
10
27
A
GLY
0.83
0.41
0.69
10
28
A
ASP
0.67
0.32
0.59
10
29
A
THR
0.60
0.33
0.58
10
30
A
HIS
0.70
0.60
0.57
10
31
A
PRO
0.82
0.47
0.52
10
32
A
LEU
1.00
0.70
0.39
10
34
A
LEU
0.65
0.70
0.28
10
35
A
ASP
0.24
0.32
0.53
10
36
A
GLU
0.94
0.33
0.51
10
39
A
ASP
0.86
0.32
0.56
10
40
A
GLU
0.94
0.33
0.50
10
42
A
GLN
0.62
0.43
0.58
10
43
A
HIS
0.59
0.60
0.41
10
44
A
LEU
0.76
0.70
0.59
10
45
A
ASP
1.00
0.32
0.65
10
46
A
ILE
0.63
0.64
0.40
10
47
A
GLY
0.59
0.41
0.54
10
48
A
LEU
0.42
0.70
0.68
10
49
A
LYS
0.43
0.25
0.63
8
50
A
GLN
0.55
0.43
0.40
8
52
A
GLN
0.49
0.43
0.59
8
53
A
TRP
0.96
0.99
0.41
10
55
A
MET
0.50
0.66
0.44
7
56
A
THR
0.23
0.33
0.58
7
57
A
GLU
1.00
0.33
0.52
7
60
A
VAL
0.52
0.56
0.50
7
61
A
ASN
0.28
0.39
0.53
8
62
A
ASN
1.00
0.39
0.31
6
63
A
PRO
0.97
0.47
0.47
4
64
A
LYS
0.88
0.25
0.38
6
68
A
ILE
0.30
0.64
0.60
2
71
A
LYS
0.65
0.25
0.58
8
72
A
TYR
0.60
0.80
0.28
10
75
A
LYS
0.78
0.25
0.46
2
76
A
PRO
0.84
0.47
0.53
10
77
A
LYS
0.61
0.25
0.62
3
78
A
TYR
0.85
0.80
0.59
10
79
A
ASN
0.58
0.39
0.69
10
80
A
VAL
0.62
0.56
0.64
10
81
A
ARG
0.53
0.51
0.76
7