Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1D9N chain A sc2

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
3
A
GLU
0.38
0.33
0.65
3
5
A
TRP
0.62
0.99
0.53
10
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.60
10
9
A
PRO
0.72
0.47
0.47
10
10
A
ALA
0.47
0.38
0.35
5
11
A
LEU
0.83
0.70
0.32
10
12
A
GLY
0.79
0.41
0.54
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.62
10
15
A
TRP
0.99
0.99
0.32
10
16
A
LYS
0.72
0.25
0.51
7
20
A
VAL
0.64
0.56
0.51
2
21
A
PHE
0.64
1.00
0.69
4
22
A
ARG
0.90
0.51
0.61
4
23
A
LYS
0.55
0.25
0.76
4
24
A
SER
0.63
0.36
0.81
4
25
A
GLY
0.91
0.41
0.82
4
26
A
ALA
0.60
0.38
0.85
4
27
A
THR
0.60
0.33
0.84
4
28
A
CYS
0.62
0.64
0.80
4
29
A
GLY
0.85
0.41
0.74
4
30
A
ARG
0.63
0.51
0.69
4
32
A
ASP
0.89
0.32
0.47
4
34
A
TYR
0.78
0.80
0.36
10
36
A
GLN
0.54
0.43
0.48
9
37
A
SER
0.78
0.36
0.52
10
38
A
PRO
0.97
0.47
0.66
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.64
10
42
A
ARG
0.60
0.51
0.64
10
43
A
ILE
0.65
0.64
0.40
10
44
A
ARG
0.90
0.51
0.50
10
45
A
SER
0.91
0.36
0.50
10
46
A
LYS
0.69
0.25
0.35
2
47
A
VAL
0.66
0.56
0.52
9
48
A
GLU
0.75
0.33
0.55
9
51
A
ARG
0.67
0.51
0.68
9
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.50
10
54
A
GLY
0.74
0.41
0.68
9
55
A
PRO
0.47
0.47
0.77
9
56
A
ALA
0.39
0.38
0.69
9
57
A
CYS
0.50
0.64
0.52
10
60
A
THR
0.47
0.33
0.60
1
61
A
LEU
0.44
0.70
0.61
3
63
A
ASP
0.79
0.32
0.42
1
64
A
PHE
0.89
1.00
0.21
10
66
A
GLN
0.52
0.43
0.51
6
67
A
GLY
0.80
0.41
0.31
2
68
A
ILE
0.49
0.64
0.51
2
69
A
LEU
0.51
0.70
0.47
7
3
A
GLU
0.38
0.33
0.66
2
4
A
ASP
0.39
0.32
0.59
1
5
A
TRP
0.62
0.99
0.51
10
6
A
LEU
0.21
0.70
0.50
10
7
A
ASP
0.59
0.32
0.59
10
9
A
PRO
0.72
0.47
0.50
10
11
A
LEU
0.83
0.70
0.29
10
12
A
GLY
0.79
0.41
0.53
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.49
4
20
A
VAL
0.64
0.56
0.51
2
21
A
PHE
0.64
1.00
0.68
10
22
A
ARG
0.90
0.51
0.59
10
23
A
LYS
0.55
0.25
0.73
8
24
A
SER
0.63
0.36
0.80
10
25
A
GLY
0.91
0.41
0.85
10
26
A
ALA
0.60
0.38
0.88
10
27
A
THR
0.60
0.33
0.83
10
28
A
CYS
0.62
0.64
0.83
10
29
A
GLY
0.85
0.41
0.72
10
30
A
ARG
0.63
0.51
0.61
10
32
A
ASP
0.89
0.32
0.45
10
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.48
7
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.70
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.63
10
43
A
ILE
0.65
0.64
0.43
10
44
A
ARG
0.90
0.51
0.52
10
45
A
SER
0.91
0.36
0.46
10
46
A
LYS
0.69
0.25
0.38
6
47
A
VAL
0.66
0.56
0.54
10
48
A
GLU
0.75
0.33
0.58
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.69
10
55
A
PRO
0.47
0.47
0.78
9
56
A
ALA
0.39
0.38
0.71
9
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.52
4
60
A
THR
0.47
0.33
0.60
3
61
A
LEU
0.44
0.70
0.60
6
63
A
ASP
0.79
0.32
0.42
5
64
A
PHE
0.89
1.00
0.25
10
66
A
GLN
0.52
0.43
0.51
10
68
A
ILE
0.49
0.64
0.49
9
69
A
LEU
0.51
0.70
0.47
9
5
A
TRP
0.62
0.99
0.51
9
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.60
10
9
A
PRO
0.72
0.47
0.51
10
11
A
LEU
0.83
0.70
0.34
10
12
A
GLY
0.79
0.41
0.56
10
13
A
PRO
0.60
0.47
0.70
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.51
3
21
A
PHE
0.64
1.00
0.66
8
22
A
ARG
0.90
0.51
0.70
8
23
A
LYS
0.55
0.25
0.80
8
24
A
SER
0.63
0.36
0.84
8
25
A
GLY
0.91
0.41
0.84
8
26
A
ALA
0.60
0.38
0.83
8
27
A
THR
0.60
0.33
0.86
8
28
A
CYS
0.62
0.64
0.81
8
29
A
GLY
0.85
0.41
0.73
8
30
A
ARG
0.63
0.51
0.63
10
32
A
ASP
0.89
0.32
0.44
3
34
A
TYR
0.78
0.80
0.32
10
36
A
GLN
0.54
0.43
0.48
9
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.70
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.60
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.41
10
45
A
SER
0.91
0.36
0.46
10
46
A
LYS
0.69
0.25
0.41
5
47
A
VAL
0.66
0.56
0.55
10
48
A
GLU
0.75
0.33
0.57
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.68
9
55
A
PRO
0.47
0.47
0.77
8
56
A
ALA
0.39
0.38
0.72
8
57
A
CYS
0.50
0.64
0.55
8
58
A
ASP
0.76
0.32
0.55
7
60
A
THR
0.47
0.33
0.60
7
61
A
LEU
0.44
0.70
0.60
5
63
A
ASP
0.79
0.32
0.40
5
64
A
PHE
0.89
1.00
0.18
10
66
A
GLN
0.52
0.43
0.50
7
67
A
GLY
0.80
0.41
0.31
6
68
A
ILE
0.49
0.64
0.49
4
69
A
LEU
0.51
0.70
0.49
4
1
A
MET
0.54
0.66
0.77
1
4
A
ASP
0.39
0.32
0.65
1
5
A
TRP
0.62
0.99
0.54
10
6
A
LEU
0.21
0.70
0.54
10
7
A
ASP
0.59
0.32
0.62
10
9
A
PRO
0.72
0.47
0.53
10
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.55
10
13
A
PRO
0.60
0.47
0.70
10
14
A
GLY
1.00
0.41
0.64
10
15
A
TRP
0.99
0.99
0.33
10
16
A
LYS
0.72
0.25
0.53
8
17
A
ARG
0.82
0.51
0.26
9
21
A
PHE
0.64
1.00
0.66
1
22
A
ARG
0.90
0.51
0.65
1
23
A
LYS
0.55
0.25
0.80
1
24
A
SER
0.63
0.36
0.76
1
25
A
GLY
0.91
0.41
0.83
1
26
A
ALA
0.60
0.38
0.88
1
27
A
THR
0.60
0.33
0.85
1
28
A
CYS
0.62
0.64
0.78
1
29
A
GLY
0.85
0.41
0.68
1
30
A
ARG
0.63
0.51
0.63
1
32
A
ASP
0.89
0.32
0.36
1
34
A
TYR
0.78
0.80
0.29
10
36
A
GLN
0.54
0.43
0.51
9
38
A
PRO
0.97
0.47
0.69
10
39
A
THR
0.58
0.33
0.77
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.64
10
42
A
ARG
0.60
0.51
0.61
10
43
A
ILE
0.65
0.64
0.40
10
44
A
ARG
0.90
0.51
0.47
10
45
A
SER
0.91
0.36
0.46
10
46
A
LYS
0.69
0.25
0.35
8
47
A
VAL
0.66
0.56
0.51
10
48
A
GLU
0.75
0.33
0.55
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.48
10
54
A
GLY
0.74
0.41
0.66
10
55
A
PRO
0.47
0.47
0.76
9
56
A
ALA
0.39
0.38
0.70
10
57
A
CYS
0.50
0.64
0.51
10
60
A
THR
0.47
0.33
0.56
5
61
A
LEU
0.44
0.70
0.57
8
63
A
ASP
0.79
0.32
0.40
6
64
A
PHE
0.89
1.00
0.21
10
66
A
GLN
0.52
0.43
0.51
9
68
A
ILE
0.49
0.64
0.49
3
69
A
LEU
0.51
0.70
0.46
10
5
A
TRP
0.62
0.99
0.54
10
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.59
10
9
A
PRO
0.72
0.47
0.47
10
10
A
ALA
0.47
0.38
0.32
2
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.53
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.50
7
20
A
VAL
0.64
0.56
0.53
2
21
A
PHE
0.64
1.00
0.68
2
22
A
ARG
0.90
0.51
0.68
2
23
A
LYS
0.55
0.25
0.80
2
24
A
SER
0.63
0.36
0.79
2
25
A
GLY
0.91
0.41
0.84
2
26
A
ALA
0.60
0.38
0.80
2
27
A
THR
0.60
0.33
0.83
2
28
A
CYS
0.62
0.64
0.74
2
29
A
GLY
0.85
0.41
0.68
2
30
A
ARG
0.63
0.51
0.63
2
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.49
8
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.64
10
43
A
ILE
0.65
0.64
0.40
10
44
A
ARG
0.90
0.51
0.49
10
45
A
SER
0.91
0.36
0.44
10
46
A
LYS
0.69
0.25
0.37
6
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.57
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.52
10
54
A
GLY
0.74
0.41
0.69
9
55
A
PRO
0.47
0.47
0.77
9
56
A
ALA
0.39
0.38
0.71
9
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.54
5
60
A
THR
0.47
0.33
0.60
6
61
A
LEU
0.44
0.70
0.60
6
63
A
ASP
0.79
0.32
0.39
5
64
A
PHE
0.89
1.00
0.21
10
65
A
LYS
0.67
0.25
0.44
1
66
A
GLN
0.52
0.43
0.47
8
68
A
ILE
0.49
0.64
0.48
8
69
A
LEU
0.51
0.70
0.48
8
5
A
TRP
0.62
0.99
0.54
10
6
A
LEU
0.21
0.70
0.51
10
7
A
ASP
0.59
0.32
0.60
10
9
A
PRO
0.72
0.47
0.50
10
10
A
ALA
0.47
0.38
0.31
6
11
A
LEU
0.83
0.70
0.31
10
12
A
GLY
0.79
0.41
0.55
10
13
A
PRO
0.60
0.47
0.69
10
14
A
GLY
1.00
0.41
0.63
10
16
A
LYS
0.72
0.25
0.52
7
21
A
PHE
0.64
1.00
0.69
9
22
A
ARG
0.90
0.51
0.67
9
23
A
LYS
0.55
0.25
0.81
9
24
A
SER
0.63
0.36
0.82
9
25
A
GLY
0.91
0.41
0.83
9
26
A
ALA
0.60
0.38
0.82
9
27
A
THR
0.60
0.33
0.82
9
28
A
CYS
0.62
0.64
0.71
9
29
A
GLY
0.85
0.41
0.70
9
30
A
ARG
0.63
0.51
0.65
9
32
A
ASP
0.89
0.32
0.41
9
34
A
TYR
0.78
0.80
0.32
10
36
A
GLN
0.54
0.43
0.50
9
38
A
PRO
0.97
0.47
0.69
10
39
A
THR
0.58
0.33
0.77
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.59
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.42
10
45
A
SER
0.91
0.36
0.48
10
46
A
LYS
0.69
0.25
0.34
3
47
A
VAL
0.66
0.56
0.50
10
48
A
GLU
0.75
0.33
0.55
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.77
10
56
A
ALA
0.39
0.38
0.71
10
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.52
9
60
A
THR
0.47
0.33
0.58
4
61
A
LEU
0.44
0.70
0.57
3
63
A
ASP
0.79
0.32
0.37
3
64
A
PHE
0.89
1.00
0.20
10
66
A
GLN
0.52
0.43
0.49
8
68
A
ILE
0.49
0.64
0.49
1
69
A
LEU
0.51
0.70
0.46
10
5
A
TRP
0.62
0.99
0.53
10
6
A
LEU
0.21
0.70
0.54
10
7
A
ASP
0.59
0.32
0.62
10
9
A
PRO
0.72
0.47
0.57
10
10
A
ALA
0.47
0.38
0.41
9
11
A
LEU
0.83
0.70
0.35
10
12
A
GLY
0.79
0.41
0.59
10
13
A
PRO
0.60
0.47
0.72
10
14
A
GLY
1.00
0.41
0.64
10
16
A
LYS
0.72
0.25
0.52
5
17
A
ARG
0.82
0.51
0.27
7
21
A
PHE
0.64
1.00
0.69
6
22
A
ARG
0.90
0.51
0.69
6
23
A
LYS
0.55
0.25
0.81
6
24
A
SER
0.63
0.36
0.80
6
25
A
GLY
0.91
0.41
0.80
6
26
A
ALA
0.60
0.38
0.84
6
27
A
THR
0.60
0.33
0.84
6
28
A
CYS
0.62
0.64
0.77
6
29
A
GLY
0.85
0.41
0.68
6
30
A
ARG
0.63
0.51
0.65
6
32
A
ASP
0.89
0.32
0.40
6
34
A
TYR
0.78
0.80
0.29
10
36
A
GLN
0.54
0.43
0.47
4
38
A
PRO
0.97
0.47
0.70
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.63
10
42
A
ARG
0.60
0.51
0.60
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.47
10
45
A
SER
0.91
0.36
0.48
10
46
A
LYS
0.69
0.25
0.38
5
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.61
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.68
9
55
A
PRO
0.47
0.47
0.78
9
56
A
ALA
0.39
0.38
0.72
9
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.56
5
60
A
THR
0.47
0.33
0.57
2
61
A
LEU
0.44
0.70
0.57
5
64
A
PHE
0.89
1.00
0.24
10
66
A
GLN
0.52
0.43
0.50
10
69
A
LEU
0.51
0.70
0.48
4
4
A
ASP
0.39
0.32
0.71
7
5
A
TRP
0.62
0.99
0.56
10
6
A
LEU
0.21
0.70
0.57
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.49
10
10
A
ALA
0.47
0.38
0.35
9
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.54
10
13
A
PRO
0.60
0.47
0.69
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.51
7
18
A
ARG
0.73
0.51
0.44
5
21
A
PHE
0.64
1.00
0.69
1
22
A
ARG
0.90
0.51
0.70
1
23
A
LYS
0.55
0.25
0.81
1
24
A
SER
0.63
0.36
0.80
1
25
A
GLY
0.91
0.41
0.87
1
26
A
ALA
0.60
0.38
0.89
1
27
A
THR
0.60
0.33
0.80
1
28
A
CYS
0.62
0.64
0.80
1
29
A
GLY
0.85
0.41
0.67
1
30
A
ARG
0.63
0.51
0.64
1
34
A
TYR
0.78
0.80
0.34
10
36
A
GLN
0.54
0.43
0.49
9
37
A
SER
0.78
0.36
0.54
10
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.63
10
42
A
ARG
0.60
0.51
0.63
10
43
A
ILE
0.65
0.64
0.39
10
44
A
ARG
0.90
0.51
0.48
10
45
A
SER
0.91
0.36
0.41
10
46
A
LYS
0.69
0.25
0.34
6
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.55
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.65
10
53
A
LEU
0.79
0.70
0.52
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.76
10
56
A
ALA
0.39
0.38
0.70
10
57
A
CYS
0.50
0.64
0.52
10
60
A
THR
0.47
0.33
0.60
9
61
A
LEU
0.44
0.70
0.61
6
63
A
ASP
0.79
0.32
0.38
2
64
A
PHE
0.89
1.00
0.12
10
65
A
LYS
0.67
0.25
0.44
1
66
A
GLN
0.52
0.43
0.50
9
67
A
GLY
0.80
0.41
0.29
5
68
A
ILE
0.49
0.64
0.51
5
69
A
LEU
0.51
0.70
0.48
9
5
A
TRP
0.62
0.99
0.49
10
6
A
LEU
0.21
0.70
0.57
10
7
A
ASP
0.59
0.32
0.59
10
9
A
PRO
0.72
0.47
0.47
10
10
A
ALA
0.47
0.38
0.34
4
11
A
LEU
0.83
0.70
0.28
10
12
A
GLY
0.79
0.41
0.52
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.49
5
20
A
VAL
0.64
0.56
0.50
2
21
A
PHE
0.64
1.00
0.68
9
22
A
ARG
0.90
0.51
0.69
9
23
A
LYS
0.55
0.25
0.73
10
24
A
SER
0.63
0.36
0.82
9
25
A
GLY
0.91
0.41
0.80
9
26
A
ALA
0.60
0.38
0.80
9
27
A
THR
0.60
0.33
0.80
9
28
A
CYS
0.62
0.64
0.81
9
29
A
GLY
0.85
0.41
0.72
9
30
A
ARG
0.63
0.51
0.66
9
34
A
TYR
0.78
0.80
0.32
10
36
A
GLN
0.54
0.43
0.48
8
38
A
PRO
0.97
0.47
0.66
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.63
10
42
A
ARG
0.60
0.51
0.64
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.45
10
45
A
SER
0.91
0.36
0.45
10
46
A
LYS
0.69
0.25
0.39
4
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.58
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.50
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.76
10
56
A
ALA
0.39
0.38
0.70
10
57
A
CYS
0.50
0.64
0.52
10
58
A
ASP
0.76
0.32
0.51
5
60
A
THR
0.47
0.33
0.61
5
61
A
LEU
0.44
0.70
0.61
4
63
A
ASP
0.79
0.32
0.41
1
64
A
PHE
0.89
1.00
0.19
10
66
A
GLN
0.52
0.43
0.50
2
68
A
ILE
0.49
0.64
0.49
1
69
A
LEU
0.51
0.70
0.48
2
3
A
GLU
0.38
0.33
0.61
1
5
A
TRP
0.62
0.99
0.51
10
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.53
10
10
A
ALA
0.47
0.38
0.36
6
11
A
LEU
0.83
0.70
0.33
10
12
A
GLY
0.79
0.41
0.56
10
13
A
PRO
0.60
0.47
0.70
10
14
A
GLY
1.00
0.41
0.63
10
16
A
LYS
0.72
0.25
0.50
7
17
A
ARG
0.82
0.51
0.23
1
21
A
PHE
0.64
1.00
0.68
5
22
A
ARG
0.90
0.51
0.65
5
23
A
LYS
0.55
0.25
0.81
5
24
A
SER
0.63
0.36
0.82
5
25
A
GLY
0.91
0.41
0.83
5
26
A
ALA
0.60
0.38
0.84
5
27
A
THR
0.60
0.33
0.85
5
28
A
CYS
0.62
0.64
0.82
5
29
A
GLY
0.85
0.41
0.75
5
30
A
ARG
0.63
0.51
0.66
5
32
A
ASP
0.89
0.32
0.39
5
34
A
TYR
0.78
0.80
0.28
10
36
A
GLN
0.54
0.43
0.48
5
38
A
PRO
0.97
0.47
0.69
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.63
10
42
A
ARG
0.60
0.51
0.59
10
43
A
ILE
0.65
0.64
0.42
10
44
A
ARG
0.90
0.51
0.48
10
45
A
SER
0.91
0.36
0.42
10
46
A
LYS
0.69
0.25
0.36
4
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.57
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.64
10
53
A
LEU
0.79
0.70
0.53
10
54
A
GLY
0.74
0.41
0.69
9
55
A
PRO
0.47
0.47
0.78
9
56
A
ALA
0.39
0.38
0.71
9
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.53
2
60
A
THR
0.47
0.33
0.60
2
61
A
LEU
0.44
0.70
0.60
4
64
A
PHE
0.89
1.00
0.25
9
66
A
GLN
0.52
0.43
0.52
9
69
A
LEU
0.51
0.70
0.49
5
5
A
TRP
0.62
0.99
0.54
10
6
A
LEU
0.21
0.70
0.48
10
7
A
ASP
0.59
0.32
0.56
10
9
A
PRO
0.72
0.47
0.47
10
10
A
ALA
0.47
0.38
0.29
8
11
A
LEU
0.83
0.70
0.26
10
12
A
GLY
0.79
0.41
0.52
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.60
10
16
A
LYS
0.72
0.25
0.49
7
20
A
VAL
0.64
0.56
0.54
3
21
A
PHE
0.64
1.00
0.68
6
22
A
ARG
0.90
0.51
0.70
6
23
A
LYS
0.55
0.25
0.84
4
24
A
SER
0.63
0.36
0.74
4
25
A
GLY
0.91
0.41
0.70
3
26
A
ALA
0.60
0.38
0.79
3
27
A
THR
0.60
0.33
0.78
2
28
A
CYS
0.62
0.64
0.63
3
29
A
GLY
0.85
0.41
0.66
3
30
A
ARG
0.63
0.51
0.62
6
32
A
ASP
0.89
0.32
0.43
6
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.50
10
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.69
10
43
A
ILE
0.65
0.64
0.43
10
44
A
ARG
0.90
0.51
0.52
10
45
A
SER
0.91
0.36
0.45
10
46
A
LYS
0.69
0.25
0.37
8
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.59
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.47
10
54
A
GLY
0.74
0.41
0.66
10
55
A
PRO
0.47
0.47
0.76
9
56
A
ALA
0.39
0.38
0.68
9
57
A
CYS
0.50
0.64
0.50
9
60
A
THR
0.47
0.33
0.59
10
61
A
LEU
0.44
0.70
0.59
8
63
A
ASP
0.79
0.32
0.40
3
64
A
PHE
0.89
1.00
0.26
10
66
A
GLN
0.52
0.43
0.47
9
68
A
ILE
0.49
0.64
0.46
10
69
A
LEU
0.51
0.70
0.44
10
1
A
MET
0.54
0.66
0.85
2
2
A
ALA
0.32
0.38
0.76
2
3
A
GLU
0.38
0.33
0.69
1
5
A
TRP
0.62
0.99
0.56
10
6
A
LEU
0.21
0.70
0.61
10
7
A
ASP
0.59
0.32
0.62
10
9
A
PRO
0.72
0.47
0.52
10
10
A
ALA
0.47
0.38
0.37
10
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.55
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.51
6
21
A
PHE
0.64
1.00
0.74
10
22
A
ARG
0.90
0.51
0.76
10
23
A
LYS
0.55
0.25
0.77
10
24
A
SER
0.63
0.36
0.68
10
25
A
GLY
0.91
0.41
0.75
10
26
A
ALA
0.60
0.38
0.80
10
27
A
THR
0.60
0.33
0.66
10
28
A
CYS
0.62
0.64
0.78
10
29
A
GLY
0.85
0.41
0.68
10
30
A
ARG
0.63
0.51
0.72
10
32
A
ASP
0.89
0.32
0.44
1
34
A
TYR
0.78
0.80
0.32
10
36
A
GLN
0.54
0.43
0.48
10
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.70
10
41
A
ASP
0.63
0.32
0.61
10
42
A
ARG
0.60
0.51
0.63
10
43
A
ILE
0.65
0.64
0.37
10
44
A
ARG
0.90
0.51
0.46
10
45
A
SER
0.91
0.36
0.42
10
46
A
LYS
0.69
0.25
0.37
3
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.50
10
54
A
GLY
0.74
0.41
0.67
10
55
A
PRO
0.47
0.47
0.76
10
56
A
ALA
0.39
0.38
0.69
10
57
A
CYS
0.50
0.64
0.51
10
60
A
THR
0.47
0.33
0.60
5
61
A
LEU
0.44
0.70
0.63
4
63
A
ASP
0.79
0.32
0.45
6
64
A
PHE
0.89
1.00
0.21
10
66
A
GLN
0.52
0.43
0.54
7
67
A
GLY
0.80
0.41
0.35
6
68
A
ILE
0.49
0.64
0.54
5
69
A
LEU
0.51
0.70
0.51
10
5
A
TRP
0.62
0.99
0.52
10
6
A
LEU
0.21
0.70
0.57
7
7
A
ASP
0.59
0.32
0.60
10
9
A
PRO
0.72
0.47
0.54
10
10
A
ALA
0.47
0.38
0.38
9
11
A
LEU
0.83
0.70
0.34
10
12
A
GLY
0.79
0.41
0.57
10
13
A
PRO
0.60
0.47
0.71
10
14
A
GLY
1.00
0.41
0.64
10
16
A
LYS
0.72
0.25
0.52
3
21
A
PHE
0.64
1.00
0.65
8
22
A
ARG
0.90
0.51
0.68
8
23
A
LYS
0.55
0.25
0.77
8
24
A
SER
0.63
0.36
0.80
8
25
A
GLY
0.91
0.41
0.81
8
26
A
ALA
0.60
0.38
0.82
8
27
A
THR
0.60
0.33
0.86
8
28
A
CYS
0.62
0.64
0.76
8
29
A
GLY
0.85
0.41
0.73
8
30
A
ARG
0.63
0.51
0.59
9
32
A
ASP
0.89
0.32
0.39
1
34
A
TYR
0.78
0.80
0.31
10
36
A
GLN
0.54
0.43
0.48
8
37
A
SER
0.78
0.36
0.53
10
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.63
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.45
10
45
A
SER
0.91
0.36
0.41
10
46
A
LYS
0.69
0.25
0.36
2
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.50
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.78
8
56
A
ALA
0.39
0.38
0.73
8
57
A
CYS
0.50
0.64
0.55
10
58
A
ASP
0.76
0.32
0.57
8
61
A
LEU
0.44
0.70
0.57
2
63
A
ASP
0.79
0.32
0.39
3
64
A
PHE
0.89
1.00
0.22
9
66
A
GLN
0.52
0.43
0.50
5
69
A
LEU
0.51
0.70
0.48
10
5
A
TRP
0.62
0.99
0.56
10
6
A
LEU
0.21
0.70
0.52
10
7
A
ASP
0.59
0.32
0.60
10
9
A
PRO
0.72
0.47
0.52
10
10
A
ALA
0.47
0.38
0.33
6
11
A
LEU
0.83
0.70
0.29
10
12
A
GLY
0.79
0.41
0.54
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.53
7
21
A
PHE
0.64
1.00
0.67
7
22
A
ARG
0.90
0.51
0.69
7
23
A
LYS
0.55
0.25
0.78
7
24
A
SER
0.63
0.36
0.72
7
25
A
GLY
0.91
0.41
0.82
7
26
A
ALA
0.60
0.38
0.86
7
27
A
THR
0.60
0.33
0.81
7
28
A
CYS
0.62
0.64
0.80
7
29
A
GLY
0.85
0.41
0.71
7
30
A
ARG
0.63
0.51
0.60
7
32
A
ASP
0.89
0.32
0.42
6
34
A
TYR
0.78
0.80
0.34
10
36
A
GLN
0.54
0.43
0.48
10
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.66
10
42
A
ARG
0.60
0.51
0.65
10
43
A
ILE
0.65
0.64
0.42
10
44
A
ARG
0.90
0.51
0.50
10
45
A
SER
0.91
0.36
0.49
10
46
A
LYS
0.69
0.25
0.37
7
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.61
10
53
A
LEU
0.79
0.70
0.47
10
54
A
GLY
0.74
0.41
0.67
10
55
A
PRO
0.47
0.47
0.77
10
56
A
ALA
0.39
0.38
0.71
10
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.50
5
60
A
THR
0.47
0.33
0.58
5
61
A
LEU
0.44
0.70
0.58
8
63
A
ASP
0.79
0.32
0.42
9
64
A
PHE
0.89
1.00
0.23
10
66
A
GLN
0.52
0.43
0.51
8
68
A
ILE
0.49
0.64
0.50
1
69
A
LEU
0.51
0.70
0.45
10
4
A
ASP
0.39
0.32
0.68
4
5
A
TRP
0.62
0.99
0.53
10
6
A
LEU
0.21
0.70
0.56
10
7
A
ASP
0.59
0.32
0.58
10
9
A
PRO
0.72
0.47
0.47
10
10
A
ALA
0.47
0.38
0.32
8
11
A
LEU
0.83
0.70
0.28
10
12
A
GLY
0.79
0.41
0.53
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.51
4
21
A
PHE
0.64
1.00
0.66
7
22
A
ARG
0.90
0.51
0.67
7
23
A
LYS
0.55
0.25
0.80
7
24
A
SER
0.63
0.36
0.79
7
25
A
GLY
0.91
0.41
0.86
7
26
A
ALA
0.60
0.38
0.84
7
27
A
THR
0.60
0.33
0.82
7
28
A
CYS
0.62
0.64
0.75
7
29
A
GLY
0.85
0.41
0.63
7
30
A
ARG
0.63
0.51
0.67
7
32
A
ASP
0.89
0.32
0.42
7
34
A
TYR
0.78
0.80
0.33
10
36
A
GLN
0.54
0.43
0.50
10
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.73
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.66
10
43
A
ILE
0.65
0.64
0.42
10
44
A
ARG
0.90
0.51
0.45
10
45
A
SER
0.91
0.36
0.42
10
46
A
LYS
0.69
0.25
0.37
8
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.57
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.49
10
54
A
GLY
0.74
0.41
0.66
10
55
A
PRO
0.47
0.47
0.74
10
56
A
ALA
0.39
0.38
0.68
10
57
A
CYS
0.50
0.64
0.50
10
58
A
ASP
0.76
0.32
0.51
5
60
A
THR
0.47
0.33
0.58
7
61
A
LEU
0.44
0.70
0.59
9
63
A
ASP
0.79
0.32
0.40
8
64
A
PHE
0.89
1.00
0.20
10
66
A
GLN
0.52
0.43
0.49
10
67
A
GLY
0.80
0.41
0.28
5
68
A
ILE
0.49
0.64
0.48
10
69
A
LEU
0.51
0.70
0.45
8
71
A
TYR
0.36
0.80
0.68
2
5
A
TRP
0.62
0.99
0.56
10
6
A
LEU
0.21
0.70
0.59
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.49
10
10
A
ALA
0.47
0.38
0.35
10
11
A
LEU
0.83
0.70
0.32
10
12
A
GLY
0.79
0.41
0.55
10
13
A
PRO
0.60
0.47
0.69
10
14
A
GLY
1.00
0.41
0.63
10
16
A
LYS
0.72
0.25
0.52
9
18
A
ARG
0.73
0.51
0.41
8
34
A
TYR
0.78
0.80
0.33
10
36
A
GLN
0.54
0.43
0.51
10
37
A
SER
0.78
0.36
0.53
10
38
A
PRO
0.97
0.47
0.70
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.62
10
43
A
ILE
0.65
0.64
0.40
10
44
A
ARG
0.90
0.51
0.49
10
45
A
SER
0.91
0.36
0.40
10
46
A
LYS
0.69
0.25
0.33
4
47
A
VAL
0.66
0.56
0.51
10
48
A
GLU
0.75
0.33
0.54
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.64
10
53
A
LEU
0.79
0.70
0.53
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.75
10
56
A
ALA
0.39
0.38
0.71
10
57
A
CYS
0.50
0.64
0.51
10
58
A
ASP
0.76
0.32
0.55
10
61
A
LEU
0.44
0.70
0.58
5
63
A
ASP
0.79
0.32
0.36
1
64
A
PHE
0.89
1.00
0.09
10
66
A
GLN
0.52
0.43
0.49
1
68
A
ILE
0.49
0.64
0.49
1
69
A
LEU
0.51
0.70
0.49
6
71
A
TYR
0.36
0.80
0.71
1
5
A
TRP
0.62
0.99
0.53
10
6
A
LEU
0.21
0.70
0.56
10
7
A
ASP
0.59
0.32
0.59
10
9
A
PRO
0.72
0.47
0.46
10
10
A
ALA
0.47
0.38
0.31
7
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.53
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.50
5
20
A
VAL
0.64
0.56
0.52
9
21
A
PHE
0.64
1.00
0.69
9
22
A
ARG
0.90
0.51
0.54
8
23
A
LYS
0.55
0.25
0.71
8
24
A
SER
0.63
0.36
0.82
8
25
A
GLY
0.91
0.41
0.84
8
26
A
ALA
0.60
0.38
0.88
8
27
A
THR
0.60
0.33
0.86
8
28
A
CYS
0.62
0.64
0.78
8
29
A
GLY
0.85
0.41
0.71
8
30
A
ARG
0.63
0.51
0.64
9
32
A
ASP
0.89
0.32
0.46
9
34
A
TYR
0.78
0.80
0.34
10
36
A
GLN
0.54
0.43
0.48
10
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.58
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.48
10
45
A
SER
0.91
0.36
0.45
9
46
A
LYS
0.69
0.25
0.37
3
47
A
VAL
0.66
0.56
0.53
9
48
A
GLU
0.75
0.33
0.57
9
51
A
ARG
0.67
0.51
0.68
9
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.68
9
55
A
PRO
0.47
0.47
0.77
9
56
A
ALA
0.39
0.38
0.70
9
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.53
4
60
A
THR
0.47
0.33
0.59
5
61
A
LEU
0.44
0.70
0.59
3
63
A
ASP
0.79
0.32
0.38
1
64
A
PHE
0.89
1.00
0.16
9
65
A
LYS
0.67
0.25
0.45
1
66
A
GLN
0.52
0.43
0.50
8
68
A
ILE
0.49
0.64
0.50
9
69
A
LEU
0.51
0.70
0.49
5
1
A
MET
0.54
0.66
0.80
1
2
A
ALA
0.32
0.38
0.69
1
5
A
TRP
0.62
0.99
0.55
10
6
A
LEU
0.21
0.70
0.53
10
7
A
ASP
0.59
0.32
0.59
10
9
A
PRO
0.72
0.47
0.50
10
10
A
ALA
0.47
0.38
0.36
6
11
A
LEU
0.83
0.70
0.34
10
12
A
GLY
0.79
0.41
0.56
10
13
A
PRO
0.60
0.47
0.69
10
14
A
GLY
1.00
0.41
0.63
10
16
A
LYS
0.72
0.25
0.51
6
20
A
VAL
0.64
0.56
0.51
1
21
A
PHE
0.64
1.00
0.68
1
22
A
ARG
0.90
0.51
0.55
1
23
A
LYS
0.55
0.25
0.74
1
24
A
SER
0.63
0.36
0.79
1
25
A
GLY
0.91
0.41
0.86
1
26
A
ALA
0.60
0.38
0.84
1
27
A
THR
0.60
0.33
0.83
1
28
A
CYS
0.62
0.64
0.78
1
29
A
GLY
0.85
0.41
0.73
1
30
A
ARG
0.63
0.51
0.68
1
32
A
ASP
0.89
0.32
0.48
1
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.50
8
38
A
PRO
0.97
0.47
0.70
10
39
A
THR
0.58
0.33
0.78
10
40
A
GLY
0.98
0.41
0.74
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.62
10
43
A
ILE
0.65
0.64
0.43
10
44
A
ARG
0.90
0.51
0.51
10
45
A
SER
0.91
0.36
0.52
10
46
A
LYS
0.69
0.25
0.37
6
47
A
VAL
0.66
0.56
0.55
10
48
A
GLU
0.75
0.33
0.59
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.65
10
53
A
LEU
0.79
0.70
0.52
10
54
A
GLY
0.74
0.41
0.71
10
55
A
PRO
0.47
0.47
0.79
9
56
A
ALA
0.39
0.38
0.73
9
57
A
CYS
0.50
0.64
0.57
10
58
A
ASP
0.76
0.32
0.55
4
60
A
THR
0.47
0.33
0.62
4
61
A
LEU
0.44
0.70
0.60
6
63
A
ASP
0.79
0.32
0.36
3
64
A
PHE
0.89
1.00
0.20
10
66
A
GLN
0.52
0.43
0.46
8
68
A
ILE
0.49
0.64
0.47
10
69
A
LEU
0.51
0.70
0.48
6
70
A
CYS
0.32
0.64
0.63
1
3
A
GLU
0.38
0.33
0.64
1
5
A
TRP
0.62
0.99
0.52
10
6
A
LEU
0.21
0.70
0.48
10
7
A
ASP
0.59
0.32
0.57
10
9
A
PRO
0.72
0.47
0.46
10
10
A
ALA
0.47
0.38
0.32
5
11
A
LEU
0.83
0.70
0.28
10
12
A
GLY
0.79
0.41
0.51
10
13
A
PRO
0.60
0.47
0.66
10
14
A
GLY
1.00
0.41
0.60
10
16
A
LYS
0.72
0.25
0.48
6
18
A
ARG
0.73
0.51
0.42
3
21
A
PHE
0.64
1.00
0.67
7
22
A
ARG
0.90
0.51
0.65
7
23
A
LYS
0.55
0.25
0.80
7
24
A
SER
0.63
0.36
0.81
7
25
A
GLY
0.91
0.41
0.83
7
26
A
ALA
0.60
0.38
0.82
7
27
A
THR
0.60
0.33
0.81
7
28
A
CYS
0.62
0.64
0.80
7
29
A
GLY
0.85
0.41
0.70
7
30
A
ARG
0.63
0.51
0.62
7
32
A
ASP
0.89
0.32
0.43
7
34
A
TYR
0.78
0.80
0.33
10
36
A
GLN
0.54
0.43
0.48
8
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.71
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.67
10
43
A
ILE
0.65
0.64
0.43
10
44
A
ARG
0.90
0.51
0.48
10
45
A
SER
0.91
0.36
0.44
10
46
A
LYS
0.69
0.25
0.37
6
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.58
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.49
10
54
A
GLY
0.74
0.41
0.68
10
55
A
PRO
0.47
0.47
0.77
10
56
A
ALA
0.39
0.38
0.70
10
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.51
6
60
A
THR
0.47
0.33
0.61
7
61
A
LEU
0.44
0.70
0.61
7
63
A
ASP
0.79
0.32
0.40
2
64
A
PHE
0.89
1.00
0.23
10
66
A
GLN
0.52
0.43
0.49
9
68
A
ILE
0.49
0.64
0.48
10
69
A
LEU
0.51
0.70
0.48
2
3
A
GLU
0.38
0.33
0.63
1
5
A
TRP
0.62
0.99
0.54
8
6
A
LEU
0.21
0.70
0.59
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.51
10
10
A
ALA
0.47
0.38
0.37
6
11
A
LEU
0.83
0.70
0.29
10
12
A
GLY
0.79
0.41
0.55
10
13
A
PRO
0.60
0.47
0.69
10
14
A
GLY
1.00
0.41
0.64
10
16
A
LYS
0.72
0.25
0.53
6
17
A
ARG
0.82
0.51
0.21
1
21
A
PHE
0.64
1.00
0.71
1
22
A
ARG
0.90
0.51
0.70
1
24
A
SER
0.63
0.36
0.84
1
25
A
GLY
0.91
0.41
0.86
1
26
A
ALA
0.60
0.38
0.84
1
27
A
THR
0.60
0.33
0.82
1
28
A
CYS
0.62
0.64
0.77
1
29
A
GLY
0.85
0.41
0.66
1
30
A
ARG
0.63
0.51
0.62
1
32
A
ASP
0.89
0.32
0.43
1
34
A
TYR
0.78
0.80
0.31
10
36
A
GLN
0.54
0.43
0.49
7
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.76
10
40
A
GLY
0.98
0.41
0.70
10
41
A
ASP
0.63
0.32
0.62
10
42
A
ARG
0.60
0.51
0.56
10
43
A
ILE
0.65
0.64
0.37
9
44
A
ARG
0.90
0.51
0.49
10
45
A
SER
0.91
0.36
0.41
10
46
A
LYS
0.69
0.25
0.33
2
47
A
VAL
0.66
0.56
0.51
10
48
A
GLU
0.75
0.33
0.54
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.53
10
54
A
GLY
0.74
0.41
0.69
9
55
A
PRO
0.47
0.47
0.77
9
56
A
ALA
0.39
0.38
0.72
9
57
A
CYS
0.50
0.64
0.53
10
58
A
ASP
0.76
0.32
0.55
2
60
A
THR
0.47
0.33
0.59
2
61
A
LEU
0.44
0.70
0.57
2
64
A
PHE
0.89
1.00
0.13
10
66
A
GLN
0.52
0.43
0.49
7
69
A
LEU
0.51
0.70
0.47
1
1
A
MET
0.54
0.66
0.81
1
2
A
ALA
0.32
0.38
0.73
7
3
A
GLU
0.38
0.33
0.65
1
4
A
ASP
0.39
0.32
0.66
1
5
A
TRP
0.62
0.99
0.56
10
6
A
LEU
0.21
0.70
0.52
10
7
A
ASP
0.59
0.32
0.62
10
9
A
PRO
0.72
0.47
0.49
10
10
A
ALA
0.47
0.38
0.38
10
11
A
LEU
0.83
0.70
0.32
10
12
A
GLY
0.79
0.41
0.57
10
13
A
PRO
0.60
0.47
0.70
10
14
A
GLY
1.00
0.41
0.64
10
16
A
LYS
0.72
0.25
0.53
7
18
A
ARG
0.73
0.51
0.43
9
20
A
VAL
0.64
0.56
0.51
8
21
A
PHE
0.64
1.00
0.60
9
22
A
ARG
0.90
0.51
0.69
9
23
A
LYS
0.55
0.25
0.79
8
24
A
SER
0.63
0.36
0.76
8
25
A
GLY
0.91
0.41
0.82
6
26
A
ALA
0.60
0.38
0.86
6
27
A
THR
0.60
0.33
0.82
6
28
A
CYS
0.62
0.64
0.77
6
29
A
GLY
0.85
0.41
0.68
6
30
A
ARG
0.63
0.51
0.63
9
32
A
ASP
0.89
0.32
0.44
9
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.51
10
37
A
SER
0.78
0.36
0.55
10
38
A
PRO
0.97
0.47
0.70
10
39
A
THR
0.58
0.33
0.77
10
40
A
GLY
0.98
0.41
0.73
10
41
A
ASP
0.63
0.32
0.65
10
42
A
ARG
0.60
0.51
0.66
10
43
A
ILE
0.65
0.64
0.41
10
44
A
ARG
0.90
0.51
0.43
10
45
A
SER
0.91
0.36
0.42
10
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.69
10
55
A
PRO
0.47
0.47
0.79
10
56
A
ALA
0.39
0.38
0.73
10
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.60
10
64
A
PHE
0.89
1.00
0.09
10
66
A
GLN
0.52
0.43
0.44
4
69
A
LEU
0.51
0.70
0.49
8
5
A
TRP
0.62
0.99
0.55
10
6
A
LEU
0.21
0.70
0.51
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.49
10
10
A
ALA
0.47
0.38
0.34
8
11
A
LEU
0.83
0.70
0.29
10
12
A
GLY
0.79
0.41
0.54
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.62
10
16
A
LYS
0.72
0.25
0.51
8
20
A
VAL
0.64
0.56
0.56
8
21
A
PHE
0.64
1.00
0.65
10
22
A
ARG
0.90
0.51
0.67
10
23
A
LYS
0.55
0.25
0.74
5
24
A
SER
0.63
0.36
0.81
10
25
A
GLY
0.91
0.41
0.87
10
26
A
ALA
0.60
0.38
0.87
10
27
A
THR
0.60
0.33
0.84
10
28
A
CYS
0.62
0.64
0.80
10
29
A
GLY
0.85
0.41
0.70
10
30
A
ARG
0.63
0.51
0.65
10
32
A
ASP
0.89
0.32
0.43
2
34
A
TYR
0.78
0.80
0.35
10
36
A
GLN
0.54
0.43
0.50
10
38
A
PRO
0.97
0.47
0.68
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.61
10
42
A
ARG
0.60
0.51
0.63
10
43
A
ILE
0.65
0.64
0.38
10
44
A
ARG
0.90
0.51
0.46
10
45
A
SER
0.91
0.36
0.42
10
46
A
LYS
0.69
0.25
0.36
7
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.56
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.62
10
53
A
LEU
0.79
0.70
0.49
10
54
A
GLY
0.74
0.41
0.66
10
55
A
PRO
0.47
0.47
0.74
10
56
A
ALA
0.39
0.38
0.68
10
57
A
CYS
0.50
0.64
0.49
10
58
A
ASP
0.76
0.32
0.51
4
60
A
THR
0.47
0.33
0.58
6
61
A
LEU
0.44
0.70
0.60
7
63
A
ASP
0.79
0.32
0.40
1
64
A
PHE
0.89
1.00
0.19
10
66
A
GLN
0.52
0.43
0.50
8
67
A
GLY
0.80
0.41
0.30
5
68
A
ILE
0.49
0.64
0.50
10
69
A
LEU
0.51
0.70
0.46
8
3
A
GLU
0.38
0.33
0.65
1
4
A
ASP
0.39
0.32
0.60
1
5
A
TRP
0.62
0.99
0.53
10
6
A
LEU
0.21
0.70
0.57
10
7
A
ASP
0.59
0.32
0.58
10
9
A
PRO
0.72
0.47
0.48
10
10
A
ALA
0.47
0.38
0.36
8
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.53
10
13
A
PRO
0.60
0.47
0.68
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.48
5
17
A
ARG
0.82
0.51
0.12
1
18
A
ARG
0.73
0.51
0.40
1
21
A
PHE
0.64
1.00
0.68
10
22
A
ARG
0.90
0.51
0.61
10
23
A
LYS
0.55
0.25
0.78
10
24
A
SER
0.63
0.36
0.79
10
25
A
GLY
0.91
0.41
0.87
10
26
A
ALA
0.60
0.38
0.90
10
27
A
THR
0.60
0.33
0.86
10
28
A
CYS
0.62
0.64
0.80
10
29
A
GLY
0.85
0.41
0.76
10
30
A
ARG
0.63
0.51
0.65
10
32
A
ASP
0.89
0.32
0.47
10
34
A
TYR
0.78
0.80
0.34
10
36
A
GLN
0.54
0.43
0.47
7
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.70
10
41
A
ASP
0.63
0.32
0.64
10
42
A
ARG
0.60
0.51
0.61
10
43
A
ILE
0.65
0.64
0.40
10
44
A
ARG
0.90
0.51
0.48
10
45
A
SER
0.91
0.36
0.50
10
46
A
LYS
0.69
0.25
0.42
7
47
A
VAL
0.66
0.56
0.56
10
48
A
GLU
0.75
0.33
0.60
10
51
A
ARG
0.67
0.51
0.70
10
52
A
TYR
0.65
0.80
0.63
10
53
A
LEU
0.79
0.70
0.52
10
54
A
GLY
0.74
0.41
0.70
10
55
A
PRO
0.47
0.47
0.78
10
56
A
ALA
0.39
0.38
0.72
10
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.54
8
60
A
THR
0.47
0.33
0.62
9
61
A
LEU
0.44
0.70
0.61
8
63
A
ASP
0.79
0.32
0.39
2
64
A
PHE
0.89
1.00
0.20
10
66
A
GLN
0.52
0.43
0.50
10
67
A
GLY
0.80
0.41
0.30
8
68
A
ILE
0.49
0.64
0.50
10
69
A
LEU
0.51
0.70
0.49
8
71
A
TYR
0.36
0.80
0.74
1
1
A
MET
0.54
0.66
0.79
8
2
A
ALA
0.32
0.38
0.76
2
3
A
GLU
0.38
0.33
0.68
2
5
A
TRP
0.62
0.99
0.52
8
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.58
10
9
A
PRO
0.72
0.47
0.51
10
10
A
ALA
0.47
0.38
0.32
1
11
A
LEU
0.83
0.70
0.30
10
12
A
GLY
0.79
0.41
0.54
10
13
A
PRO
0.60
0.47
0.67
10
14
A
GLY
1.00
0.41
0.61
10
16
A
LYS
0.72
0.25
0.50
3
17
A
ARG
0.82
0.51
0.22
4
21
A
PHE
0.64
1.00
0.67
2
22
A
ARG
0.90
0.51
0.71
2
23
A
LYS
0.55
0.25
0.74
2
24
A
SER
0.63
0.36
0.83
2
26
A
ALA
0.60
0.38
0.79
2
27
A
THR
0.60
0.33
0.84
2
28
A
CYS
0.62
0.64
0.84
2
29
A
GLY
0.85
0.41
0.76
2
30
A
ARG
0.63
0.51
0.67
2
32
A
ASP
0.89
0.32
0.41
2
34
A
TYR
0.78
0.80
0.29
10
36
A
GLN
0.54
0.43
0.45
1
38
A
PRO
0.97
0.47
0.67
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.69
10
41
A
ASP
0.63
0.32
0.59
10
42
A
ARG
0.60
0.51
0.58
10
43
A
ILE
0.65
0.64
0.38
10
44
A
ARG
0.90
0.51
0.47
10
45
A
SER
0.91
0.36
0.44
10
46
A
LYS
0.69
0.25
0.40
7
47
A
VAL
0.66
0.56
0.53
10
48
A
GLU
0.75
0.33
0.57
10
51
A
ARG
0.67
0.51
0.68
10
52
A
TYR
0.65
0.80
0.61
10
53
A
LEU
0.79
0.70
0.50
10
54
A
GLY
0.74
0.41
0.68
9
55
A
PRO
0.47
0.47
0.76
9
56
A
ALA
0.39
0.38
0.70
9
57
A
CYS
0.50
0.64
0.52
9
58
A
ASP
0.76
0.32
0.52
8
60
A
THR
0.47
0.33
0.60
7
61
A
LEU
0.44
0.70
0.60
7
63
A
ASP
0.79
0.32
0.40
6
64
A
PHE
0.89
1.00
0.15
10
66
A
GLN
0.52
0.43
0.52
5
69
A
LEU
0.51
0.70
0.47
10
2
A
ALA
0.32
0.38
0.78
1
3
A
GLU
0.38
0.33
0.63
1
4
A
ASP
0.39
0.32
0.67
1
5
A
TRP
0.62
0.99
0.51
10
6
A
LEU
0.21
0.70
0.58
10
7
A
ASP
0.59
0.32
0.61
10
9
A
PRO
0.72
0.47
0.50
10
10
A
ALA
0.47
0.38
0.37
8
11
A
LEU
0.83
0.70
0.32
10
12
A
GLY
0.79
0.41
0.56
10
13
A
PRO
0.60
0.47
0.70
10
14
A
GLY
1.00
0.41
0.64
10
16
A
LYS
0.72
0.25
0.52
9
18
A
ARG
0.73
0.51
0.43
4
21
A
PHE
0.64
1.00
0.66
9
22
A
ARG
0.90
0.51
0.65
9
23
A
LYS
0.55
0.25
0.80
9
24
A
SER
0.63
0.36
0.79
9
25
A
GLY
0.91
0.41
0.84
9
26
A
ALA
0.60
0.38
0.88
9
27
A
THR
0.60
0.33
0.84
9
28
A
CYS
0.62
0.64
0.77
9
29
A
GLY
0.85
0.41
0.67
8
30
A
ARG
0.63
0.51
0.63
9
32
A
ASP
0.89
0.32
0.40
9
34
A
TYR
0.78
0.80
0.32
10
36
A
GLN
0.54
0.43
0.52
9
38
A
PRO
0.97
0.47
0.70
10
39
A
THR
0.58
0.33
0.75
10
40
A
GLY
0.98
0.41
0.72
10
41
A
ASP
0.63
0.32
0.63
10
42
A
ARG
0.60
0.51
0.60
10
43
A
ILE
0.65
0.64
0.37
10
44
A
ARG
0.90
0.51
0.49
10
45
A
SER
0.91
0.36
0.40
10
46
A
LYS
0.69
0.25
0.33
5
47
A
VAL
0.66
0.56
0.52
10
48
A
GLU
0.75
0.33
0.55
10
51
A
ARG
0.67
0.51
0.69
10
52
A
TYR
0.65
0.80
0.64
10
53
A
LEU
0.79
0.70
0.51
10
54
A
GLY
0.74
0.41
0.69
10
55
A
PRO
0.47
0.47
0.78
10
56
A
ALA
0.39
0.38
0.71
10
57
A
CYS
0.50
0.64
0.54
10
58
A
ASP
0.76
0.32
0.52
6
60
A
THR
0.47
0.33
0.60
8
61
A
LEU
0.44
0.70
0.59
6
64
A
PHE
0.89
1.00
0.15
10
66
A
GLN
0.52
0.43
0.49
10
67
A
GLY
0.80
0.41
0.31
8
68
A
ILE
0.49
0.64
0.49
8
69
A
LEU
0.51
0.70
0.48
9
71
A
TYR
0.36
0.80
0.70
1