Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DQC chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
8
A
ARG
0.25
0.51
0.34
10
9
A
TYR
0.28
0.80
0.51
10
12
A
CYS
0.46
0.64
0.43
10
13
A
LEU
0.29
0.70
0.67
10
14
A
ASP
0.28
0.32
0.64
10
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.50
10
17
A
PRO
0.54
0.47
0.44
10
19
A
VAL
0.53
0.56
0.29
10
21
A
LEU
0.60
0.70
0.37
10
22
A
TYR
0.35
0.80
0.39
10
23
A
SER
0.66
0.36
0.14
9
24
A
CYS
0.99
0.64
0.27
10
25
A
CYS
0.50
0.64
0.25
10
26
A
SER
0.58
0.36
0.08
7
27
A
PHE
0.79
1.00
0.02
10
28
A
TYR
0.65
0.80
0.01
10
30
A
CYS
1.00
0.64
0.36
10
31
A
HIS
0.33
0.60
0.59
10
32
A
LYS
0.47
0.25
0.73
10
34
A
LEU
0.32
0.70
0.57
10
36
A
ARG
0.38
0.51
0.48
10
37
A
LEU
0.47
0.70
0.14
10
40
A
CYS
1.00
0.64
0.42
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.59
10
44
A
LEU
0.82
0.70
0.57
10
45
A
HIS
0.56
0.60
0.32
10
46
A
TYR
0.76
0.80
0.25
10
47
A
ASN
0.71
0.39
0.49
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.51
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.62
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
8
65
A
ASN
0.21
0.39
0.47
10
66
A
LYS
0.17
0.25
0.62
10
67
A
GLU
0.12
0.33
0.66
10
68
A
CYS
0.20
0.64
0.44
10
69
A
HIS
0.06
0.60
0.68
10
70
A
LEU
0.08
0.70
0.66
2
71
A
TRP
0.06
0.99
0.52
10
72
A
LYS
0.04
0.25
0.71
2
73
A
THR
0.02
0.33
0.54
10
1
A
TYR
0.10
0.80
0.65
7
2
A
LEU
0.06
0.70
0.74
5
3
A
ALA
0.14
0.38
0.72
5
4
A
PHE
0.28
1.00
0.65
7
5
A
ARG
0.16
0.51
0.82
5
6
A
CYS
0.83
0.64
0.69
6
7
A
GLY
0.62
0.41
0.59
6
8
A
ARG
0.25
0.51
0.41
10
9
A
TYR
0.28
0.80
0.58
8
12
A
CYS
0.46
0.64
0.50
9
13
A
LEU
0.29
0.70
0.71
5
14
A
ASP
0.28
0.32
0.74
8
15
A
ASP
0.45
0.32
0.66
8
16
A
GLY
0.61
0.41
0.57
10
17
A
PRO
0.54
0.47
0.48
10
19
A
VAL
0.53
0.56
0.28
10
21
A
LEU
0.60
0.70
0.37
9
22
A
TYR
0.35
0.80
0.39
9
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.36
10
26
A
SER
0.58
0.36
0.22
10
27
A
PHE
0.79
1.00
0.18
10
31
A
HIS
0.33
0.60
0.68
9
32
A
LYS
0.47
0.25
0.80
8
33
A
CYS
0.77
0.64
0.71
6
34
A
LEU
0.32
0.70
0.67
8
36
A
ARG
0.38
0.51
0.55
10
37
A
LEU
0.47
0.70
0.31
10
38
A
GLU
0.51
0.33
0.41
10
39
A
ASN
0.40
0.39
0.54
10
40
A
CYS
1.00
0.64
0.52
10
41
A
PRO
0.76
0.47
0.70
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.72
10
44
A
LEU
0.82
0.70
0.66
10
45
A
HIS
0.56
0.60
0.47
10
47
A
ASN
0.71
0.39
0.49
10
48
A
ALA
0.45
0.38
0.41
2
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.70
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.49
10
54
A
ASP
0.84
0.32
0.62
10
55
A
TRP
0.64
0.99
0.78
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.54
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.60
7
65
A
ASN
0.21
0.39
0.53
9
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.65
10
69
A
HIS
0.06
0.60
0.68
10
71
A
TRP
0.06
0.99
0.61
10
1
A
TYR
0.10
0.80
0.80
1
2
A
LEU
0.06
0.70
0.71
10
3
A
ALA
0.14
0.38
0.72
1
4
A
PHE
0.28
1.00
0.61
7
5
A
ARG
0.16
0.51
0.78
1
6
A
CYS
0.83
0.64
0.68
2
7
A
GLY
0.62
0.41
0.58
1
8
A
ARG
0.25
0.51
0.41
10
9
A
TYR
0.28
0.80
0.58
1
12
A
CYS
0.46
0.64
0.47
10
13
A
LEU
0.29
0.70
0.69
10
14
A
ASP
0.28
0.32
0.72
10
15
A
ASP
0.45
0.32
0.67
10
16
A
GLY
0.61
0.41
0.51
10
17
A
PRO
0.54
0.47
0.42
5
18
A
ASN
0.48
0.39
0.32
1
19
A
VAL
0.53
0.56
0.24
10
21
A
LEU
0.60
0.70
0.34
10
22
A
TYR
0.35
0.80
0.43
10
24
A
CYS
0.99
0.64
0.31
10
25
A
CYS
0.50
0.64
0.35
10
27
A
PHE
0.79
1.00
0.11
10
29
A
ASN
0.39
0.39
0.40
10
31
A
HIS
0.33
0.60
0.68
7
32
A
LYS
0.47
0.25
0.79
1
33
A
CYS
0.77
0.64
0.72
1
34
A
LEU
0.32
0.70
0.61
7
36
A
ARG
0.38
0.51
0.55
10
37
A
LEU
0.47
0.70
0.30
10
38
A
GLU
0.51
0.33
0.36
4
39
A
ASN
0.40
0.39
0.48
10
40
A
CYS
1.00
0.64
0.51
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.68
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.48
10
48
A
ALA
0.45
0.38
0.33
1
49
A
TYR
0.27
0.80
0.66
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.63
10
52
A
VAL
0.43
0.56
0.55
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.48
10
60
A
GLY
0.39
0.41
0.43
7
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.50
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.68
10
68
A
CYS
0.20
0.64
0.56
10
69
A
HIS
0.06
0.60
0.75
1
70
A
LEU
0.08
0.70
0.70
1
71
A
TRP
0.06
0.99
0.61
10
72
A
LYS
0.04
0.25
0.77
1
73
A
THR
0.02
0.33
0.55
10
6
A
CYS
0.83
0.64
0.60
3
7
A
GLY
0.62
0.41
0.56
3
8
A
ARG
0.25
0.51
0.34
10
9
A
TYR
0.28
0.80
0.44
6
12
A
CYS
0.46
0.64
0.44
3
15
A
ASP
0.45
0.32
0.62
1
16
A
GLY
0.61
0.41
0.53
1
17
A
PRO
0.54
0.47
0.44
9
19
A
VAL
0.53
0.56
0.26
9
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.42
10
23
A
SER
0.66
0.36
0.18
10
24
A
CYS
0.99
0.64
0.38
10
25
A
CYS
0.50
0.64
0.29
10
26
A
SER
0.58
0.36
0.09
10
33
A
CYS
0.77
0.64
0.64
3
34
A
LEU
0.32
0.70
0.60
3
36
A
ARG
0.38
0.51
0.47
10
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.28
9
39
A
ASN
0.40
0.39
0.44
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.63
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.68
10
44
A
LEU
0.82
0.70
0.62
10
48
A
ALA
0.45
0.38
0.37
10
49
A
TYR
0.27
0.80
0.67
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.59
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.43
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.62
10
65
A
ASN
0.21
0.39
0.49
10
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.51
10
69
A
HIS
0.06
0.60
0.68
2
70
A
LEU
0.08
0.70
0.59
10
71
A
TRP
0.06
0.99
0.61
6
8
A
ARG
0.25
0.51
0.33
10
9
A
TYR
0.28
0.80
0.50
3
11
A
PRO
0.28
0.47
0.28
8
17
A
PRO
0.54
0.47
0.44
10
19
A
VAL
0.53
0.56
0.28
10
21
A
LEU
0.60
0.70
0.37
10
22
A
TYR
0.35
0.80
0.44
10
23
A
SER
0.66
0.36
0.23
10
24
A
CYS
0.99
0.64
0.35
10
25
A
CYS
0.50
0.64
0.27
10
36
A
ARG
0.38
0.51
0.49
10
37
A
LEU
0.47
0.70
0.17
10
38
A
GLU
0.51
0.33
0.28
10
39
A
ASN
0.40
0.39
0.39
10
40
A
CYS
1.00
0.64
0.48
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
47
A
ASN
0.71
0.39
0.43
10
48
A
ALA
0.45
0.38
0.39
9
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.55
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.51
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.61
10
65
A
ASN
0.21
0.39
0.53
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.46
10
69
A
HIS
0.06
0.60
0.58
10
70
A
LEU
0.08
0.70
0.70
1
71
A
TRP
0.06
0.99
0.50
10
1
A
TYR
0.10
0.80
0.63
6
4
A
PHE
0.28
1.00
0.64
2
6
A
CYS
0.83
0.64
0.69
4
7
A
GLY
0.62
0.41
0.60
4
8
A
ARG
0.25
0.51
0.42
10
9
A
TYR
0.28
0.80
0.58
10
12
A
CYS
0.46
0.64
0.46
10
13
A
LEU
0.29
0.70
0.69
6
14
A
ASP
0.28
0.32
0.72
10
15
A
ASP
0.45
0.32
0.65
10
16
A
GLY
0.61
0.41
0.55
10
17
A
PRO
0.54
0.47
0.45
10
18
A
ASN
0.48
0.39
0.34
5
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.35
10
22
A
TYR
0.35
0.80
0.44
6
25
A
CYS
0.50
0.64
0.28
10
26
A
SER
0.58
0.36
0.15
10
27
A
PHE
0.79
1.00
0.09
10
29
A
ASN
0.39
0.39
0.37
1
31
A
HIS
0.33
0.60
0.65
10
32
A
LYS
0.47
0.25
0.78
10
33
A
CYS
0.77
0.64
0.68
6
34
A
LEU
0.32
0.70
0.64
8
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.25
10
38
A
GLU
0.51
0.33
0.35
10
39
A
ASN
0.40
0.39
0.47
10
40
A
CYS
1.00
0.64
0.44
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.63
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.44
10
48
A
ALA
0.45
0.38
0.40
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.62
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.43
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.56
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.61
6
65
A
ASN
0.21
0.39
0.51
6
66
A
LYS
0.17
0.25
0.67
10
67
A
GLU
0.12
0.33
0.67
1
68
A
CYS
0.20
0.64
0.54
10
69
A
HIS
0.06
0.60
0.66
10
70
A
LEU
0.08
0.70
0.64
2
71
A
TRP
0.06
0.99
0.56
10
72
A
LYS
0.04
0.25
0.74
1
73
A
THR
0.02
0.33
0.79
1
8
A
ARG
0.25
0.51
0.38
9
9
A
TYR
0.28
0.80
0.54
8
12
A
CYS
0.46
0.64
0.44
2
13
A
LEU
0.29
0.70
0.66
2
14
A
ASP
0.28
0.32
0.69
2
15
A
ASP
0.45
0.32
0.64
4
16
A
GLY
0.61
0.41
0.55
5
17
A
PRO
0.54
0.47
0.47
4
18
A
ASN
0.48
0.39
0.32
2
19
A
VAL
0.53
0.56
0.24
10
21
A
LEU
0.60
0.70
0.31
9
22
A
TYR
0.35
0.80
0.41
6
25
A
CYS
0.50
0.64
0.37
10
27
A
PHE
0.79
1.00
0.13
10
29
A
ASN
0.39
0.39
0.36
1
31
A
HIS
0.33
0.60
0.65
3
34
A
LEU
0.32
0.70
0.61
3
36
A
ARG
0.38
0.51
0.55
10
37
A
LEU
0.47
0.70
0.28
10
38
A
GLU
0.51
0.33
0.41
10
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.53
10
41
A
PRO
0.76
0.47
0.70
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.64
10
44
A
LEU
0.82
0.70
0.62
10
45
A
HIS
0.56
0.60
0.45
10
47
A
ASN
0.71
0.39
0.50
10
48
A
ALA
0.45
0.38
0.44
10
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.52
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.40
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.58
6
65
A
ASN
0.21
0.39
0.50
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.56
10
69
A
HIS
0.06
0.60
0.74
10
70
A
LEU
0.08
0.70
0.76
1
71
A
TRP
0.06
0.99
0.53
10
8
A
ARG
0.25
0.51
0.38
8
9
A
TYR
0.28
0.80
0.50
7
11
A
PRO
0.28
0.47
0.34
1
12
A
CYS
0.46
0.64
0.43
1
16
A
GLY
0.61
0.41
0.47
1
19
A
VAL
0.53
0.56
0.23
10
21
A
LEU
0.60
0.70
0.42
10
22
A
TYR
0.35
0.80
0.49
10
23
A
SER
0.66
0.36
0.24
1
25
A
CYS
0.50
0.64
0.22
10
28
A
TYR
0.65
0.80
0.04
10
36
A
ARG
0.38
0.51
0.44
10
37
A
LEU
0.47
0.70
0.13
10
38
A
GLU
0.51
0.33
0.23
10
39
A
ASN
0.40
0.39
0.41
10
40
A
CYS
1.00
0.64
0.43
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.61
10
44
A
LEU
0.82
0.70
0.59
10
45
A
HIS
0.56
0.60
0.40
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.41
9
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.65
10
65
A
ASN
0.21
0.39
0.56
10
66
A
LYS
0.17
0.25
0.66
10
69
A
HIS
0.06
0.60
0.55
10
71
A
TRP
0.06
0.99
0.49
10
6
A
CYS
0.83
0.64
0.63
4
7
A
GLY
0.62
0.41
0.57
3
8
A
ARG
0.25
0.51
0.38
10
9
A
TYR
0.28
0.80
0.54
10
11
A
PRO
0.28
0.47
0.30
10
13
A
LEU
0.29
0.70
0.61
9
14
A
ASP
0.28
0.32
0.63
9
15
A
ASP
0.45
0.32
0.61
9
16
A
GLY
0.61
0.41
0.50
10
17
A
PRO
0.54
0.47
0.44
10
18
A
ASN
0.48
0.39
0.28
2
19
A
VAL
0.53
0.56
0.23
10
21
A
LEU
0.60
0.70
0.37
10
22
A
TYR
0.35
0.80
0.41
5
25
A
CYS
0.50
0.64
0.33
10
26
A
SER
0.58
0.36
0.18
10
27
A
PHE
0.79
1.00
0.09
10
29
A
ASN
0.39
0.39
0.32
1
31
A
HIS
0.33
0.60
0.64
8
32
A
LYS
0.47
0.25
0.77
3
33
A
CYS
0.77
0.64
0.67
4
34
A
LEU
0.32
0.70
0.63
8
36
A
ARG
0.38
0.51
0.53
10
37
A
LEU
0.47
0.70
0.25
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.50
10
41
A
PRO
0.76
0.47
0.68
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.46
10
47
A
ASN
0.71
0.39
0.45
10
48
A
ALA
0.45
0.38
0.40
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.48
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.62
5
65
A
ASN
0.21
0.39
0.56
5
66
A
LYS
0.17
0.25
0.66
10
67
A
GLU
0.12
0.33
0.69
10
69
A
HIS
0.06
0.60
0.65
10
70
A
LEU
0.08
0.70
0.68
1
71
A
TRP
0.06
0.99
0.54
10
72
A
LYS
0.04
0.25
0.79
1
73
A
THR
0.02
0.33
0.71
1
4
A
PHE
0.28
1.00
0.62
1
8
A
ARG
0.25
0.51
0.36
10
9
A
TYR
0.28
0.80
0.47
6
12
A
CYS
0.46
0.64
0.40
5
13
A
LEU
0.29
0.70
0.63
5
14
A
ASP
0.28
0.32
0.65
5
15
A
ASP
0.45
0.32
0.66
10
16
A
GLY
0.61
0.41
0.52
10
17
A
PRO
0.54
0.47
0.44
10
18
A
ASN
0.48
0.39
0.25
5
19
A
VAL
0.53
0.56
0.17
10
21
A
LEU
0.60
0.70
0.34
10
22
A
TYR
0.35
0.80
0.38
10
25
A
CYS
0.50
0.64
0.24
10
26
A
SER
0.58
0.36
0.05
10
31
A
HIS
0.33
0.60
0.62
1
36
A
ARG
0.38
0.51
0.49
10
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.28
9
39
A
ASN
0.40
0.39
0.37
9
40
A
CYS
1.00
0.64
0.40
10
41
A
PRO
0.76
0.47
0.63
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.58
10
44
A
LEU
0.82
0.70
0.55
10
45
A
HIS
0.56
0.60
0.38
10
46
A
TYR
0.76
0.80
0.20
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.41
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.53
10
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.63
10
57
A
SER
0.38
0.36
0.75
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.56
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.51
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.65
10
68
A
CYS
0.20
0.64
0.54
10
71
A
TRP
0.06
0.99
0.55
10
73
A
THR
0.02
0.33
0.62
9
2
A
LEU
0.06
0.70
0.74
1
3
A
ALA
0.14
0.38
0.74
1
4
A
PHE
0.28
1.00
0.58
3
5
A
ARG
0.16
0.51
0.76
3
6
A
CYS
0.83
0.64
0.64
3
7
A
GLY
0.62
0.41
0.54
3
8
A
ARG
0.25
0.51
0.36
10
9
A
TYR
0.28
0.80
0.55
9
13
A
LEU
0.29
0.70
0.61
10
14
A
ASP
0.28
0.32
0.70
10
15
A
ASP
0.45
0.32
0.68
10
16
A
GLY
0.61
0.41
0.54
10
17
A
PRO
0.54
0.47
0.45
10
18
A
ASN
0.48
0.39
0.29
3
19
A
VAL
0.53
0.56
0.24
10
21
A
LEU
0.60
0.70
0.37
10
22
A
TYR
0.35
0.80
0.37
10
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.31
10
27
A
PHE
0.79
1.00
0.12
10
30
A
CYS
1.00
0.64
0.49
10
31
A
HIS
0.33
0.60
0.62
10
32
A
LYS
0.47
0.25
0.79
10
33
A
CYS
0.77
0.64
0.70
3
34
A
LEU
0.32
0.70
0.64
10
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.37
5
39
A
ASN
0.40
0.39
0.47
10
40
A
CYS
1.00
0.64
0.50
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.80
10
43
A
GLY
0.89
0.41
0.64
10
44
A
LEU
0.82
0.70
0.62
10
46
A
TYR
0.76
0.80
0.28
10
47
A
ASN
0.71
0.39
0.49
10
48
A
ALA
0.45
0.38
0.38
3
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.57
10
52
A
VAL
0.43
0.56
0.59
10
53
A
CYS
1.00
0.64
0.54
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.61
10
57
A
SER
0.38
0.36
0.75
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.53
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.66
10
69
A
HIS
0.06
0.60
0.65
10
71
A
TRP
0.06
0.99
0.58
10
1
A
TYR
0.10
0.80
0.67
9
6
A
CYS
0.83
0.64
0.66
1
7
A
GLY
0.62
0.41
0.59
1
8
A
ARG
0.25
0.51
0.37
10
9
A
TYR
0.28
0.80
0.46
9
12
A
CYS
0.46
0.64
0.46
1
15
A
ASP
0.45
0.32
0.67
7
16
A
GLY
0.61
0.41
0.58
7
17
A
PRO
0.54
0.47
0.46
7
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.37
9
22
A
TYR
0.35
0.80
0.39
10
24
A
CYS
0.99
0.64
0.38
10
25
A
CYS
0.50
0.64
0.35
10
26
A
SER
0.58
0.36
0.16
10
27
A
PHE
0.79
1.00
0.11
10
31
A
HIS
0.33
0.60
0.67
6
33
A
CYS
0.77
0.64
0.69
1
34
A
LEU
0.32
0.70
0.65
6
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.46
10
40
A
CYS
1.00
0.64
0.47
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.46
10
48
A
ALA
0.45
0.38
0.43
10
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.46
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.60
10
61
A
CYS
0.95
0.64
0.53
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
9
66
A
LYS
0.17
0.25
0.66
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.55
10
69
A
HIS
0.06
0.60
0.69
10
70
A
LEU
0.08
0.70
0.73
5
71
A
TRP
0.06
0.99
0.57
10
72
A
LYS
0.04
0.25
0.73
5
73
A
THR
0.02
0.33
0.79
5
1
A
TYR
0.10
0.80
0.75
7
4
A
PHE
0.28
1.00
0.65
1
6
A
CYS
0.83
0.64
0.65
3
7
A
GLY
0.62
0.41
0.57
3
8
A
ARG
0.25
0.51
0.34
10
9
A
TYR
0.28
0.80
0.54
10
12
A
CYS
0.46
0.64
0.46
10
13
A
LEU
0.29
0.70
0.69
4
14
A
ASP
0.28
0.32
0.72
10
15
A
ASP
0.45
0.32
0.65
10
16
A
GLY
0.61
0.41
0.54
10
17
A
PRO
0.54
0.47
0.43
9
18
A
ASN
0.48
0.39
0.30
4
19
A
VAL
0.53
0.56
0.26
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.40
10
24
A
CYS
0.99
0.64
0.31
10
25
A
CYS
0.50
0.64
0.36
10
26
A
SER
0.58
0.36
0.16
10
27
A
PHE
0.79
1.00
0.09
10
29
A
ASN
0.39
0.39
0.36
2
31
A
HIS
0.33
0.60
0.60
10
33
A
CYS
0.77
0.64
0.69
3
34
A
LEU
0.32
0.70
0.62
9
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.35
9
39
A
ASN
0.40
0.39
0.50
10
40
A
CYS
1.00
0.64
0.47
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.63
10
47
A
ASN
0.71
0.39
0.47
10
48
A
ALA
0.45
0.38
0.40
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.46
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.78
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.63
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.48
10
66
A
LYS
0.17
0.25
0.62
10
67
A
GLU
0.12
0.33
0.66
10
68
A
CYS
0.20
0.64
0.43
10
69
A
HIS
0.06
0.60
0.63
10
71
A
TRP
0.06
0.99
0.54
10
1
A
TYR
0.10
0.80
0.85
2
2
A
LEU
0.06
0.70
0.79
2
3
A
ALA
0.14
0.38
0.81
2
4
A
PHE
0.28
1.00
0.72
2
5
A
ARG
0.16
0.51
0.76
2
6
A
CYS
0.83
0.64
0.56
3
7
A
GLY
0.62
0.41
0.57
2
8
A
ARG
0.25
0.51
0.42
10
9
A
TYR
0.28
0.80
0.40
10
11
A
PRO
0.28
0.47
0.30
10
12
A
CYS
0.46
0.64
0.42
10
13
A
LEU
0.29
0.70
0.67
7
14
A
ASP
0.28
0.32
0.65
10
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.54
10
17
A
PRO
0.54
0.47
0.40
10
18
A
ASN
0.48
0.39
0.31
7
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.43
10
22
A
TYR
0.35
0.80
0.47
10
25
A
CYS
0.50
0.64
0.28
10
27
A
PHE
0.79
1.00
0.00
10
29
A
ASN
0.39
0.39
0.28
3
31
A
HIS
0.33
0.60
0.60
10
32
A
LYS
0.47
0.25
0.74
2
33
A
CYS
0.77
0.64
0.58
3
34
A
LEU
0.32
0.70
0.54
8
36
A
ARG
0.38
0.51
0.40
10
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.23
10
39
A
ASN
0.40
0.39
0.37
7
40
A
CYS
1.00
0.64
0.35
10
41
A
PRO
0.76
0.47
0.59
10
42
A
LYS
0.49
0.25
0.74
10
43
A
GLY
0.89
0.41
0.59
10
44
A
LEU
0.82
0.70
0.55
10
45
A
HIS
0.56
0.60
0.40
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.42
2
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.39
10
54
A
ASP
0.84
0.32
0.56
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.63
7
65
A
ASN
0.21
0.39
0.49
10
66
A
LYS
0.17
0.25
0.68
10
67
A
GLU
0.12
0.33
0.65
10
68
A
CYS
0.20
0.64
0.58
10
70
A
LEU
0.08
0.70
0.58
10
71
A
TRP
0.06
0.99
0.56
10
72
A
LYS
0.04
0.25
0.52
10
73
A
THR
0.02
0.33
0.68
7
1
A
TYR
0.10
0.80
0.78
8
2
A
LEU
0.06
0.70
0.72
8
3
A
ALA
0.14
0.38
0.73
9
4
A
PHE
0.28
1.00
0.58
10
5
A
ARG
0.16
0.51
0.79
10
6
A
CYS
0.83
0.64
0.62
10
7
A
GLY
0.62
0.41
0.58
10
9
A
TYR
0.28
0.80
0.46
10
12
A
CYS
0.46
0.64
0.45
10
13
A
LEU
0.29
0.70
0.68
9
14
A
ASP
0.28
0.32
0.69
10
15
A
ASP
0.45
0.32
0.67
10
16
A
GLY
0.61
0.41
0.56
10
17
A
PRO
0.54
0.47
0.44
10
18
A
ASN
0.48
0.39
0.33
1
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.40
10
22
A
TYR
0.35
0.80
0.42
10
25
A
CYS
0.50
0.64
0.31
10
26
A
SER
0.58
0.36
0.09
10
27
A
PHE
0.79
1.00
0.03
10
30
A
CYS
1.00
0.64
0.41
10
31
A
HIS
0.33
0.60
0.64
10
32
A
LYS
0.47
0.25
0.77
10
33
A
CYS
0.77
0.64
0.66
10
34
A
LEU
0.32
0.70
0.59
10
36
A
ARG
0.38
0.51
0.47
10
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.29
7
39
A
ASN
0.40
0.39
0.43
10
40
A
CYS
1.00
0.64
0.40
10
41
A
PRO
0.76
0.47
0.62
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.66
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.46
10
46
A
TYR
0.76
0.80
0.21
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.43
10
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.67
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.44
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.80
10
58
A
LYS
0.61
0.25
0.78
10
59
A
ALA
0.72
0.38
0.54
10
60
A
GLY
0.39
0.41
0.56
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
10
66
A
LYS
0.17
0.25
0.62
10
67
A
GLU
0.12
0.33
0.65
10
68
A
CYS
0.20
0.64
0.46
10
71
A
TRP
0.06
0.99
0.58
10
6
A
CYS
0.83
0.64
0.57
3
7
A
GLY
0.62
0.41
0.54
2
8
A
ARG
0.25
0.51
0.37
8
9
A
TYR
0.28
0.80
0.39
6
12
A
CYS
0.46
0.64
0.42
2
15
A
ASP
0.45
0.32
0.60
1
16
A
GLY
0.61
0.41
0.50
1
17
A
PRO
0.54
0.47
0.40
9
19
A
VAL
0.53
0.56
0.23
10
21
A
LEU
0.60
0.70
0.39
9
22
A
TYR
0.35
0.80
0.47
10
24
A
CYS
0.99
0.64
0.36
10
25
A
CYS
0.50
0.64
0.27
10
31
A
HIS
0.33
0.60
0.62
1
32
A
LYS
0.47
0.25
0.71
1
33
A
CYS
0.77
0.64
0.57
3
34
A
LEU
0.32
0.70
0.56
4
36
A
ARG
0.38
0.51
0.44
10
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.26
10
39
A
ASN
0.40
0.39
0.43
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.62
10
44
A
LEU
0.82
0.70
0.59
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.44
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.65
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.58
10
61
A
CYS
0.95
0.64
0.53
10
62
A
THR
0.27
0.33
0.62
10
64
A
VAL
0.26
0.56
0.64
9
65
A
ASN
0.21
0.39
0.56
10
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.45
10
69
A
HIS
0.06
0.60
0.51
10
70
A
LEU
0.08
0.70
0.69
5
71
A
TRP
0.06
0.99
0.57
7
72
A
LYS
0.04
0.25
0.79
1
73
A
THR
0.02
0.33
0.80
1
6
A
CYS
0.83
0.64
0.62
1
7
A
GLY
0.62
0.41
0.58
1
8
A
ARG
0.25
0.51
0.41
9
9
A
TYR
0.28
0.80
0.43
9
15
A
ASP
0.45
0.32
0.66
2
16
A
GLY
0.61
0.41
0.51
4
17
A
PRO
0.54
0.47
0.43
10
19
A
VAL
0.53
0.56
0.28
4
21
A
LEU
0.60
0.70
0.41
3
22
A
TYR
0.35
0.80
0.42
9
25
A
CYS
0.50
0.64
0.26
10
26
A
SER
0.58
0.36
0.02
10
28
A
TYR
0.65
0.80
0.06
10
30
A
CYS
1.00
0.64
0.42
4
34
A
LEU
0.32
0.70
0.52
1
36
A
ARG
0.38
0.51
0.42
9
37
A
LEU
0.47
0.70
0.11
10
38
A
GLU
0.51
0.33
0.21
6
39
A
ASN
0.40
0.39
0.36
6
40
A
CYS
1.00
0.64
0.42
10
41
A
PRO
0.76
0.47
0.62
10
42
A
LYS
0.49
0.25
0.72
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.62
10
45
A
HIS
0.56
0.60
0.46
10
48
A
ALA
0.45
0.38
0.38
9
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.63
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.48
10
53
A
CYS
1.00
0.64
0.41
10
54
A
ASP
0.84
0.32
0.55
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.61
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.61
10
64
A
VAL
0.26
0.56
0.61
2
65
A
ASN
0.21
0.39
0.44
9
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.70
10
68
A
CYS
0.20
0.64
0.58
10
69
A
HIS
0.06
0.60
0.71
10
71
A
TRP
0.06
0.99
0.56
9
73
A
THR
0.02
0.33
0.54
9
1
A
TYR
0.10
0.80
0.80
4
2
A
LEU
0.06
0.70
0.70
6
3
A
ALA
0.14
0.38
0.74
4
4
A
PHE
0.28
1.00
0.63
9
5
A
ARG
0.16
0.51
0.73
8
6
A
CYS
0.83
0.64
0.67
9
7
A
GLY
0.62
0.41
0.58
9
8
A
ARG
0.25
0.51
0.36
10
9
A
TYR
0.28
0.80
0.51
10
13
A
LEU
0.29
0.70
0.66
4
14
A
ASP
0.28
0.32
0.69
10
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.53
10
17
A
PRO
0.54
0.47
0.43
6
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.36
10
22
A
TYR
0.35
0.80
0.36
9
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.29
10
27
A
PHE
0.79
1.00
0.08
10
30
A
CYS
1.00
0.64
0.43
10
31
A
HIS
0.33
0.60
0.68
10
32
A
LYS
0.47
0.25
0.78
10
33
A
CYS
0.77
0.64
0.71
9
34
A
LEU
0.32
0.70
0.61
10
36
A
ARG
0.38
0.51
0.51
10
37
A
LEU
0.47
0.70
0.20
10
38
A
GLU
0.51
0.33
0.32
4
39
A
ASN
0.40
0.39
0.42
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.73
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.46
10
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.65
10
51
A
LYS
0.44
0.25
0.58
10
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.61
6
65
A
ASN
0.21
0.39
0.53
9
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.68
9
68
A
CYS
0.20
0.64
0.49
10
69
A
HIS
0.06
0.60
0.68
10
71
A
TRP
0.06
0.99
0.56
10
1
A
TYR
0.10
0.80
0.75
3
2
A
LEU
0.06
0.70
0.65
3
3
A
ALA
0.14
0.38
0.71
3
4
A
PHE
0.28
1.00
0.61
5
6
A
CYS
0.83
0.64
0.69
2
7
A
GLY
0.62
0.41
0.59
5
8
A
ARG
0.25
0.51
0.38
8
9
A
TYR
0.28
0.80
0.53
5
12
A
CYS
0.46
0.64
0.47
3
15
A
ASP
0.45
0.32
0.67
1
16
A
GLY
0.61
0.41
0.58
1
17
A
PRO
0.54
0.47
0.48
1
19
A
VAL
0.53
0.56
0.27
9
21
A
LEU
0.60
0.70
0.32
9
22
A
TYR
0.35
0.80
0.38
9
25
A
CYS
0.50
0.64
0.30
10
26
A
SER
0.58
0.36
0.15
10
29
A
ASN
0.39
0.39
0.44
10
31
A
HIS
0.33
0.60
0.65
2
32
A
LYS
0.47
0.25
0.81
1
33
A
CYS
0.77
0.64
0.70
2
34
A
LEU
0.32
0.70
0.67
2
36
A
ARG
0.38
0.51
0.57
10
37
A
LEU
0.47
0.70
0.26
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.49
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.43
10
48
A
ALA
0.45
0.38
0.42
10
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.64
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.48
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.59
10
65
A
ASN
0.21
0.39
0.47
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.66
10
68
A
CYS
0.20
0.64
0.51
10
69
A
HIS
0.06
0.60
0.67
10
70
A
LEU
0.08
0.70
0.71
7
71
A
TRP
0.06
0.99
0.58
10
72
A
LYS
0.04
0.25
0.80
6
73
A
THR
0.02
0.33
0.74
6
6
A
CYS
0.83
0.64
0.65
3
7
A
GLY
0.62
0.41
0.59
2
8
A
ARG
0.25
0.51
0.40
10
9
A
TYR
0.28
0.80
0.49
10
12
A
CYS
0.46
0.64
0.43
10
13
A
LEU
0.29
0.70
0.64
2
14
A
ASP
0.28
0.32
0.66
9
15
A
ASP
0.45
0.32
0.69
9
16
A
GLY
0.61
0.41
0.57
10
17
A
PRO
0.54
0.47
0.48
10
18
A
ASN
0.48
0.39
0.31
2
19
A
VAL
0.53
0.56
0.26
10
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.38
10
24
A
CYS
0.99
0.64
0.32
10
25
A
CYS
0.50
0.64
0.38
10
26
A
SER
0.58
0.36
0.19
10
27
A
PHE
0.79
1.00
0.10
10
29
A
ASN
0.39
0.39
0.39
2
31
A
HIS
0.33
0.60
0.66
8
32
A
LYS
0.47
0.25
0.79
1
33
A
CYS
0.77
0.64
0.67
3
34
A
LEU
0.32
0.70
0.64
8
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.26
10
38
A
GLU
0.51
0.33
0.36
7
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.52
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.81
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.49
10
48
A
ALA
0.45
0.38
0.42
10
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.58
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.49
10
54
A
ASP
0.84
0.32
0.61
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.62
10
64
A
VAL
0.26
0.56
0.60
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.68
10
68
A
CYS
0.20
0.64
0.56
10
69
A
HIS
0.06
0.60
0.72
1
70
A
LEU
0.08
0.70
0.72
1
71
A
TRP
0.06
0.99
0.57
10
73
A
THR
0.02
0.33
0.68
8
1
A
TYR
0.10
0.80
0.72
2
2
A
LEU
0.06
0.70
0.60
2
8
A
ARG
0.25
0.51
0.41
7
9
A
TYR
0.28
0.80
0.43
6
15
A
ASP
0.45
0.32
0.68
1
16
A
GLY
0.61
0.41
0.55
1
17
A
PRO
0.54
0.47
0.48
8
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.39
10
26
A
SER
0.58
0.36
0.12
10
27
A
PHE
0.79
1.00
0.08
10
30
A
CYS
1.00
0.64
0.43
2
34
A
LEU
0.32
0.70
0.66
1
36
A
ARG
0.38
0.51
0.52
9
37
A
LEU
0.47
0.70
0.20
10
38
A
GLU
0.51
0.33
0.33
9
39
A
ASN
0.40
0.39
0.43
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.60
10
44
A
LEU
0.82
0.70
0.58
10
45
A
HIS
0.56
0.60
0.40
10
47
A
ASN
0.71
0.39
0.50
10
48
A
ALA
0.45
0.38
0.46
10
49
A
TYR
0.27
0.80
0.72
10
50
A
LEU
0.39
0.70
0.69
10
51
A
LYS
0.44
0.25
0.59
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.50
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.64
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.61
10
64
A
VAL
0.26
0.56
0.59
9
65
A
ASN
0.21
0.39
0.51
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.64
1
68
A
CYS
0.20
0.64
0.54
10
69
A
HIS
0.06
0.60
0.71
1
70
A
LEU
0.08
0.70
0.59
1
71
A
TRP
0.06
0.99
0.57
10
6
A
CYS
0.83
0.64
0.65
6
7
A
GLY
0.62
0.41
0.60
3
8
A
ARG
0.25
0.51
0.43
10
9
A
TYR
0.28
0.80
0.47
10
12
A
CYS
0.46
0.64
0.48
5
13
A
LEU
0.29
0.70
0.69
4
14
A
ASP
0.28
0.32
0.72
4
15
A
ASP
0.45
0.32
0.66
9
16
A
GLY
0.61
0.41
0.56
10
17
A
PRO
0.54
0.47
0.49
10
18
A
ASN
0.48
0.39
0.33
4
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.35
10
22
A
TYR
0.35
0.80
0.43
7
25
A
CYS
0.50
0.64
0.37
10
27
A
PHE
0.79
1.00
0.14
10
29
A
ASN
0.39
0.39
0.41
1
31
A
HIS
0.33
0.60
0.69
8
32
A
LYS
0.47
0.25
0.78
3
33
A
CYS
0.77
0.64
0.67
6
34
A
LEU
0.32
0.70
0.64
8
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.29
10
38
A
GLU
0.51
0.33
0.40
10
39
A
ASN
0.40
0.39
0.46
10
40
A
CYS
1.00
0.64
0.46
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.67
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.46
10
47
A
ASN
0.71
0.39
0.49
10
48
A
ALA
0.45
0.38
0.44
5
49
A
TYR
0.27
0.80
0.72
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.58
10
61
A
CYS
0.95
0.64
0.44
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.57
7
65
A
ASN
0.21
0.39
0.51
7
66
A
LYS
0.17
0.25
0.65
10
68
A
CYS
0.20
0.64
0.59
10
71
A
TRP
0.06
0.99
0.58
10
6
A
CYS
0.83
0.64
0.55
1
8
A
ARG
0.25
0.51
0.35
10
9
A
TYR
0.28
0.80
0.51
10
13
A
LEU
0.29
0.70
0.63
6
14
A
ASP
0.28
0.32
0.69
10
15
A
ASP
0.45
0.32
0.62
10
16
A
GLY
0.61
0.41
0.52
10
17
A
PRO
0.54
0.47
0.42
10
18
A
ASN
0.48
0.39
0.33
6
19
A
VAL
0.53
0.56
0.28
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.36
10
24
A
CYS
0.99
0.64
0.35
10
25
A
CYS
0.50
0.64
0.32
10
27
A
PHE
0.79
1.00
0.08
10
29
A
ASN
0.39
0.39
0.34
10
31
A
HIS
0.33
0.60
0.63
10
32
A
LYS
0.47
0.25
0.75
10
33
A
CYS
0.77
0.64
0.61
1
34
A
LEU
0.32
0.70
0.57
7
36
A
ARG
0.38
0.51
0.46
10
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.30
10
39
A
ASN
0.40
0.39
0.45
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.63
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.45
10
48
A
ALA
0.45
0.38
0.41
10
49
A
TYR
0.27
0.80
0.62
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.62
10
52
A
VAL
0.43
0.56
0.55
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.61
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.58
10
65
A
ASN
0.21
0.39
0.47
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.47
10
69
A
HIS
0.06
0.60
0.67
10
70
A
LEU
0.08
0.70
0.70
1
71
A
TRP
0.06
0.99
0.54
10
2
A
LEU
0.06
0.70
0.75
1
3
A
ALA
0.14
0.38
0.79
1
4
A
PHE
0.28
1.00
0.66
2
5
A
ARG
0.16
0.51
0.76
1
6
A
CYS
0.83
0.64
0.59
2
7
A
GLY
0.62
0.41
0.53
2
8
A
ARG
0.25
0.51
0.33
10
9
A
TYR
0.28
0.80
0.40
10
12
A
CYS
0.46
0.64
0.45
10
13
A
LEU
0.29
0.70
0.68
5
14
A
ASP
0.28
0.32
0.72
10
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.51
10
17
A
PRO
0.54
0.47
0.42
10
18
A
ASN
0.48
0.39
0.33
5
19
A
VAL
0.53
0.56
0.29
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.37
10
27
A
PHE
0.79
1.00
0.01
10
29
A
ASN
0.39
0.39
0.31
4
31
A
HIS
0.33
0.60
0.64
10
32
A
LYS
0.47
0.25
0.76
10
33
A
CYS
0.77
0.64
0.61
2
34
A
LEU
0.32
0.70
0.57
10
36
A
ARG
0.38
0.51
0.47
10
37
A
LEU
0.47
0.70
0.10
10
38
A
GLU
0.51
0.33
0.25
10
39
A
ASN
0.40
0.39
0.33
10
40
A
CYS
1.00
0.64
0.37
10
41
A
PRO
0.76
0.47
0.60
10
42
A
LYS
0.49
0.25
0.69
10
43
A
GLY
0.89
0.41
0.67
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.42
10
48
A
ALA
0.45
0.38
0.38
10
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.49
10
53
A
CYS
1.00
0.64
0.41
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.62
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.57
7
65
A
ASN
0.21
0.39
0.46
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.54
10
69
A
HIS
0.06
0.60
0.65
1
70
A
LEU
0.08
0.70
0.42
10
71
A
TRP
0.06
0.99
0.52
10
1
A
TYR
0.10
0.80
0.80
8
2
A
LEU
0.06
0.70
0.66
8
3
A
ALA
0.14
0.38
0.66
8
4
A
PHE
0.28
1.00
0.59
8
5
A
ARG
0.16
0.51
0.80
6
6
A
CYS
0.83
0.64
0.66
6
7
A
GLY
0.62
0.41
0.57
6
8
A
ARG
0.25
0.51
0.37
10
9
A
TYR
0.28
0.80
0.51
10
12
A
CYS
0.46
0.64
0.39
9
13
A
LEU
0.29
0.70
0.63
6
14
A
ASP
0.28
0.32
0.67
9
15
A
ASP
0.45
0.32
0.66
8
16
A
GLY
0.61
0.41
0.50
10
17
A
PRO
0.54
0.47
0.38
4
18
A
ASN
0.48
0.39
0.30
2
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.39
10
24
A
CYS
0.99
0.64
0.32
10
27
A
PHE
0.79
1.00
0.01
10
31
A
HIS
0.33
0.60
0.63
2
34
A
LEU
0.32
0.70
0.61
2
36
A
ARG
0.38
0.51
0.49
10
37
A
LEU
0.47
0.70
0.16
10
38
A
GLU
0.51
0.33
0.26
10
39
A
ASN
0.40
0.39
0.35
10
40
A
CYS
1.00
0.64
0.36
10
41
A
PRO
0.76
0.47
0.58
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.62
10
44
A
LEU
0.82
0.70
0.56
10
45
A
HIS
0.56
0.60
0.44
10
46
A
TYR
0.76
0.80
0.18
10
47
A
ASN
0.71
0.39
0.44
10
48
A
ALA
0.45
0.38
0.38
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.66
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.40
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.44
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.59
10
65
A
ASN
0.21
0.39
0.44
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.56
10
68
A
CYS
0.20
0.64
0.53
10
69
A
HIS
0.06
0.60
0.66
1
70
A
LEU
0.08
0.70
0.70
1
71
A
TRP
0.06
0.99
0.48
10