Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DQC chain A sc2

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
8
A
ARG
0.25
0.51
0.34
1
15
A
ASP
0.45
0.32
0.64
2
16
A
GLY
0.61
0.41
0.50
2
17
A
PRO
0.54
0.47
0.44
10
19
A
VAL
0.53
0.56
0.29
10
21
A
LEU
0.60
0.70
0.37
9
22
A
TYR
0.35
0.80
0.39
10
23
A
SER
0.66
0.36
0.14
1
24
A
CYS
0.99
0.64
0.27
10
27
A
PHE
0.79
1.00
0.02
10
28
A
TYR
0.65
0.80
0.01
9
30
A
CYS
1.00
0.64
0.36
2
36
A
ARG
0.38
0.51
0.48
9
37
A
LEU
0.47
0.70
0.14
9
38
A
GLU
0.51
0.33
0.29
7
39
A
ASN
0.40
0.39
0.40
3
40
A
CYS
1.00
0.64
0.42
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.59
10
44
A
LEU
0.82
0.70
0.57
10
45
A
HIS
0.56
0.60
0.32
7
46
A
TYR
0.76
0.80
0.25
10
47
A
ASN
0.71
0.39
0.49
10
48
A
ALA
0.45
0.38
0.37
5
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.51
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.62
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
9
65
A
ASN
0.21
0.39
0.47
10
66
A
LYS
0.17
0.25
0.62
10
67
A
GLU
0.12
0.33
0.66
10
68
A
CYS
0.20
0.64
0.44
10
69
A
HIS
0.06
0.60
0.68
1
71
A
TRP
0.06
0.99
0.52
10
72
A
LYS
0.04
0.25
0.71
3
73
A
THR
0.02
0.33
0.54
7
8
A
ARG
0.25
0.51
0.41
7
9
A
TYR
0.28
0.80
0.58
1
12
A
CYS
0.46
0.64
0.50
9
13
A
LEU
0.29
0.70
0.71
1
14
A
ASP
0.28
0.32
0.74
9
15
A
ASP
0.45
0.32
0.66
9
16
A
GLY
0.61
0.41
0.57
10
17
A
PRO
0.54
0.47
0.48
9
19
A
VAL
0.53
0.56
0.28
10
21
A
LEU
0.60
0.70
0.37
8
22
A
TYR
0.35
0.80
0.39
10
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.36
10
26
A
SER
0.58
0.36
0.22
7
27
A
PHE
0.79
1.00
0.18
10
31
A
HIS
0.33
0.60
0.68
9
32
A
LYS
0.47
0.25
0.80
9
34
A
LEU
0.32
0.70
0.67
1
36
A
ARG
0.38
0.51
0.55
10
37
A
LEU
0.47
0.70
0.31
10
38
A
GLU
0.51
0.33
0.41
10
39
A
ASN
0.40
0.39
0.54
10
40
A
CYS
1.00
0.64
0.52
10
41
A
PRO
0.76
0.47
0.70
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.72
10
44
A
LEU
0.82
0.70
0.66
10
45
A
HIS
0.56
0.60
0.47
10
47
A
ASN
0.71
0.39
0.49
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.70
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.49
10
54
A
ASP
0.84
0.32
0.62
10
55
A
TRP
0.64
0.99
0.78
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.54
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.60
8
65
A
ASN
0.21
0.39
0.53
10
66
A
LYS
0.17
0.25
0.63
9
67
A
GLU
0.12
0.33
0.65
10
69
A
HIS
0.06
0.60
0.68
5
71
A
TRP
0.06
0.99
0.61
7
12
A
CYS
0.46
0.64
0.47
6
13
A
LEU
0.29
0.70
0.69
6
14
A
ASP
0.28
0.32
0.72
6
15
A
ASP
0.45
0.32
0.67
6
16
A
GLY
0.61
0.41
0.51
7
17
A
PRO
0.54
0.47
0.42
1
19
A
VAL
0.53
0.56
0.24
8
22
A
TYR
0.35
0.80
0.43
10
24
A
CYS
0.99
0.64
0.31
10
25
A
CYS
0.50
0.64
0.35
8
27
A
PHE
0.79
1.00
0.11
10
29
A
ASN
0.39
0.39
0.40
6
31
A
HIS
0.33
0.60
0.68
1
32
A
LYS
0.47
0.25
0.79
1
34
A
LEU
0.32
0.70
0.61
1
36
A
ARG
0.38
0.51
0.55
9
37
A
LEU
0.47
0.70
0.30
9
38
A
GLU
0.51
0.33
0.36
8
39
A
ASN
0.40
0.39
0.48
8
40
A
CYS
1.00
0.64
0.51
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.68
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.48
10
49
A
TYR
0.27
0.80
0.66
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.63
10
52
A
VAL
0.43
0.56
0.55
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.48
10
60
A
GLY
0.39
0.41
0.43
8
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.60
8
65
A
ASN
0.21
0.39
0.50
8
66
A
LYS
0.17
0.25
0.63
8
67
A
GLU
0.12
0.33
0.68
10
68
A
CYS
0.20
0.64
0.56
10
71
A
TRP
0.06
0.99
0.61
4
73
A
THR
0.02
0.33
0.55
6
8
A
ARG
0.25
0.51
0.34
3
15
A
ASP
0.45
0.32
0.62
1
16
A
GLY
0.61
0.41
0.53
1
17
A
PRO
0.54
0.47
0.44
9
19
A
VAL
0.53
0.56
0.26
7
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.42
10
23
A
SER
0.66
0.36
0.18
3
24
A
CYS
0.99
0.64
0.38
10
25
A
CYS
0.50
0.64
0.29
10
26
A
SER
0.58
0.36
0.09
10
36
A
ARG
0.38
0.51
0.47
10
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.28
10
39
A
ASN
0.40
0.39
0.44
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.63
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.68
10
44
A
LEU
0.82
0.70
0.62
10
48
A
ALA
0.45
0.38
0.37
10
49
A
TYR
0.27
0.80
0.67
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.59
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.43
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.62
10
65
A
ASN
0.21
0.39
0.49
10
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.51
10
70
A
LEU
0.08
0.70
0.59
3
8
A
ARG
0.25
0.51
0.33
6
12
A
CYS
0.46
0.64
0.42
1
14
A
ASP
0.28
0.32
0.66
1
15
A
ASP
0.45
0.32
0.62
2
16
A
GLY
0.61
0.41
0.53
2
17
A
PRO
0.54
0.47
0.44
10
19
A
VAL
0.53
0.56
0.28
4
21
A
LEU
0.60
0.70
0.37
9
22
A
TYR
0.35
0.80
0.44
10
23
A
SER
0.66
0.36
0.23
6
24
A
CYS
0.99
0.64
0.35
10
25
A
CYS
0.50
0.64
0.27
10
31
A
HIS
0.33
0.60
0.56
1
32
A
LYS
0.47
0.25
0.76
1
36
A
ARG
0.38
0.51
0.49
10
37
A
LEU
0.47
0.70
0.17
10
38
A
GLU
0.51
0.33
0.28
10
39
A
ASN
0.40
0.39
0.39
10
40
A
CYS
1.00
0.64
0.48
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
47
A
ASN
0.71
0.39
0.43
10
48
A
ALA
0.45
0.38
0.39
4
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.55
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.51
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.61
9
65
A
ASN
0.21
0.39
0.53
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.46
10
69
A
HIS
0.06
0.60
0.58
10
71
A
TRP
0.06
0.99
0.50
10
9
A
TYR
0.28
0.80
0.58
1
12
A
CYS
0.46
0.64
0.46
6
13
A
LEU
0.29
0.70
0.69
1
14
A
ASP
0.28
0.32
0.72
6
15
A
ASP
0.45
0.32
0.65
7
16
A
GLY
0.61
0.41
0.55
9
17
A
PRO
0.54
0.47
0.45
7
19
A
VAL
0.53
0.56
0.27
9
25
A
CYS
0.50
0.64
0.28
9
26
A
SER
0.58
0.36
0.15
6
27
A
PHE
0.79
1.00
0.09
10
31
A
HIS
0.33
0.60
0.65
7
32
A
LYS
0.47
0.25
0.78
6
34
A
LEU
0.32
0.70
0.64
1
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.25
10
38
A
GLU
0.51
0.33
0.35
9
39
A
ASN
0.40
0.39
0.47
9
40
A
CYS
1.00
0.64
0.44
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.63
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.44
9
48
A
ALA
0.45
0.38
0.40
9
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.62
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.43
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.56
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.61
8
65
A
ASN
0.21
0.39
0.51
4
66
A
LYS
0.17
0.25
0.67
10
67
A
GLU
0.12
0.33
0.67
4
68
A
CYS
0.20
0.64
0.54
9
69
A
HIS
0.06
0.60
0.66
3
71
A
TRP
0.06
0.99
0.56
6
8
A
ARG
0.25
0.51
0.38
2
9
A
TYR
0.28
0.80
0.54
7
12
A
CYS
0.46
0.64
0.44
3
13
A
LEU
0.29
0.70
0.66
3
14
A
ASP
0.28
0.32
0.69
3
15
A
ASP
0.45
0.32
0.64
8
16
A
GLY
0.61
0.41
0.55
8
17
A
PRO
0.54
0.47
0.47
8
18
A
ASN
0.48
0.39
0.32
1
19
A
VAL
0.53
0.56
0.24
10
21
A
LEU
0.60
0.70
0.31
9
25
A
CYS
0.50
0.64
0.37
10
27
A
PHE
0.79
1.00
0.13
10
31
A
HIS
0.33
0.60
0.65
7
32
A
LYS
0.47
0.25
0.76
2
34
A
LEU
0.32
0.70
0.61
7
36
A
ARG
0.38
0.51
0.55
10
37
A
LEU
0.47
0.70
0.28
10
38
A
GLU
0.51
0.33
0.41
10
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.53
10
41
A
PRO
0.76
0.47
0.70
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.64
10
44
A
LEU
0.82
0.70
0.62
10
45
A
HIS
0.56
0.60
0.45
10
47
A
ASN
0.71
0.39
0.50
10
48
A
ALA
0.45
0.38
0.44
10
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.52
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.40
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.58
9
65
A
ASN
0.21
0.39
0.50
10
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.67
9
68
A
CYS
0.20
0.64
0.56
10
69
A
HIS
0.06
0.60
0.74
9
70
A
LEU
0.08
0.70
0.76
1
71
A
TRP
0.06
0.99
0.53
10
8
A
ARG
0.25
0.51
0.38
1
9
A
TYR
0.28
0.80
0.50
3
12
A
CYS
0.46
0.64
0.43
3
13
A
LEU
0.29
0.70
0.67
2
14
A
ASP
0.28
0.32
0.65
3
15
A
ASP
0.45
0.32
0.62
4
16
A
GLY
0.61
0.41
0.47
5
17
A
PRO
0.54
0.47
0.38
4
18
A
ASN
0.48
0.39
0.28
2
19
A
VAL
0.53
0.56
0.23
10
21
A
LEU
0.60
0.70
0.42
10
22
A
TYR
0.35
0.80
0.49
10
25
A
CYS
0.50
0.64
0.22
10
28
A
TYR
0.65
0.80
0.04
10
31
A
HIS
0.33
0.60
0.58
4
34
A
LEU
0.32
0.70
0.51
3
36
A
ARG
0.38
0.51
0.44
9
37
A
LEU
0.47
0.70
0.13
10
38
A
GLU
0.51
0.33
0.23
9
39
A
ASN
0.40
0.39
0.41
10
40
A
CYS
1.00
0.64
0.43
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.61
10
44
A
LEU
0.82
0.70
0.59
10
45
A
HIS
0.56
0.60
0.40
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.41
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.65
10
65
A
ASN
0.21
0.39
0.56
10
66
A
LYS
0.17
0.25
0.66
10
67
A
GLU
0.12
0.33
0.71
7
69
A
HIS
0.06
0.60
0.55
10
71
A
TRP
0.06
0.99
0.49
10
13
A
LEU
0.29
0.70
0.61
5
14
A
ASP
0.28
0.32
0.63
5
15
A
ASP
0.45
0.32
0.61
5
16
A
GLY
0.61
0.41
0.50
10
17
A
PRO
0.54
0.47
0.44
9
19
A
VAL
0.53
0.56
0.23
10
21
A
LEU
0.60
0.70
0.37
10
22
A
TYR
0.35
0.80
0.41
3
25
A
CYS
0.50
0.64
0.33
10
26
A
SER
0.58
0.36
0.18
6
27
A
PHE
0.79
1.00
0.09
10
31
A
HIS
0.33
0.60
0.64
1
32
A
LYS
0.47
0.25
0.77
1
34
A
LEU
0.32
0.70
0.63
1
36
A
ARG
0.38
0.51
0.53
10
37
A
LEU
0.47
0.70
0.25
10
38
A
GLU
0.51
0.33
0.36
8
39
A
ASN
0.40
0.39
0.50
10
41
A
PRO
0.76
0.47
0.68
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.46
10
47
A
ASN
0.71
0.39
0.45
10
48
A
ALA
0.45
0.38
0.40
9
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.48
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.62
10
65
A
ASN
0.21
0.39
0.56
9
66
A
LYS
0.17
0.25
0.66
10
67
A
GLU
0.12
0.33
0.69
8
69
A
HIS
0.06
0.60
0.65
7
71
A
TRP
0.06
0.99
0.54
7
8
A
ARG
0.25
0.51
0.36
2
17
A
PRO
0.54
0.47
0.44
9
19
A
VAL
0.53
0.56
0.17
10
21
A
LEU
0.60
0.70
0.34
10
22
A
TYR
0.35
0.80
0.38
9
25
A
CYS
0.50
0.64
0.24
9
26
A
SER
0.58
0.36
0.05
2
36
A
ARG
0.38
0.51
0.49
9
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.28
9
39
A
ASN
0.40
0.39
0.37
8
40
A
CYS
1.00
0.64
0.40
10
41
A
PRO
0.76
0.47
0.63
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.58
10
44
A
LEU
0.82
0.70
0.55
10
45
A
HIS
0.56
0.60
0.38
10
46
A
TYR
0.76
0.80
0.20
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.41
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.53
10
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.63
10
57
A
SER
0.38
0.36
0.75
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.56
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.51
9
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.65
4
68
A
CYS
0.20
0.64
0.54
8
71
A
TRP
0.06
0.99
0.55
8
73
A
THR
0.02
0.33
0.62
8
13
A
LEU
0.29
0.70
0.61
6
14
A
ASP
0.28
0.32
0.70
6
15
A
ASP
0.45
0.32
0.68
6
16
A
GLY
0.61
0.41
0.54
9
17
A
PRO
0.54
0.47
0.45
10
19
A
VAL
0.53
0.56
0.24
10
21
A
LEU
0.60
0.70
0.37
6
22
A
TYR
0.35
0.80
0.37
10
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.31
10
27
A
PHE
0.79
1.00
0.12
10
30
A
CYS
1.00
0.64
0.49
9
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.37
8
39
A
ASN
0.40
0.39
0.47
10
40
A
CYS
1.00
0.64
0.50
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.80
10
43
A
GLY
0.89
0.41
0.64
10
44
A
LEU
0.82
0.70
0.62
10
46
A
TYR
0.76
0.80
0.28
10
47
A
ASN
0.71
0.39
0.49
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.57
10
52
A
VAL
0.43
0.56
0.59
10
53
A
CYS
1.00
0.64
0.54
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.61
10
57
A
SER
0.38
0.36
0.75
10
58
A
LYS
0.61
0.25
0.75
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.59
10
64
A
VAL
0.26
0.56
0.60
6
65
A
ASN
0.21
0.39
0.53
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.66
10
69
A
HIS
0.06
0.60
0.65
2
70
A
LEU
0.08
0.70
0.70
1
71
A
TRP
0.06
0.99
0.58
2
9
A
TYR
0.28
0.80
0.46
1
12
A
CYS
0.46
0.64
0.46
5
13
A
LEU
0.29
0.70
0.69
2
14
A
ASP
0.28
0.32
0.70
5
15
A
ASP
0.45
0.32
0.67
5
16
A
GLY
0.61
0.41
0.58
10
17
A
PRO
0.54
0.47
0.46
2
18
A
ASN
0.48
0.39
0.32
1
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.37
9
22
A
TYR
0.35
0.80
0.39
10
24
A
CYS
0.99
0.64
0.38
10
25
A
CYS
0.50
0.64
0.35
10
26
A
SER
0.58
0.36
0.16
8
27
A
PHE
0.79
1.00
0.11
10
31
A
HIS
0.33
0.60
0.67
5
32
A
LYS
0.47
0.25
0.79
2
34
A
LEU
0.32
0.70
0.65
1
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.46
10
40
A
CYS
1.00
0.64
0.47
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.76
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.46
10
48
A
ALA
0.45
0.38
0.43
10
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.60
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.46
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.60
10
61
A
CYS
0.95
0.64
0.53
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
9
66
A
LYS
0.17
0.25
0.66
10
67
A
GLU
0.12
0.33
0.67
10
68
A
CYS
0.20
0.64
0.55
10
69
A
HIS
0.06
0.60
0.69
6
71
A
TRP
0.06
0.99
0.57
10
12
A
CYS
0.46
0.64
0.46
4
14
A
ASP
0.28
0.32
0.72
4
15
A
ASP
0.45
0.32
0.65
4
16
A
GLY
0.61
0.41
0.54
10
19
A
VAL
0.53
0.56
0.26
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.40
10
24
A
CYS
0.99
0.64
0.31
10
25
A
CYS
0.50
0.64
0.36
10
26
A
SER
0.58
0.36
0.16
6
27
A
PHE
0.79
1.00
0.09
10
31
A
HIS
0.33
0.60
0.60
4
36
A
ARG
0.38
0.51
0.52
10
37
A
LEU
0.47
0.70
0.23
10
38
A
GLU
0.51
0.33
0.35
10
39
A
ASN
0.40
0.39
0.50
10
40
A
CYS
1.00
0.64
0.47
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.63
10
47
A
ASN
0.71
0.39
0.47
10
48
A
ALA
0.45
0.38
0.40
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.46
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.78
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.54
10
61
A
CYS
0.95
0.64
0.50
10
62
A
THR
0.27
0.33
0.63
10
64
A
VAL
0.26
0.56
0.60
10
65
A
ASN
0.21
0.39
0.48
9
66
A
LYS
0.17
0.25
0.62
10
67
A
GLU
0.12
0.33
0.66
10
68
A
CYS
0.20
0.64
0.43
10
69
A
HIS
0.06
0.60
0.63
7
71
A
TRP
0.06
0.99
0.54
6
9
A
TYR
0.28
0.80
0.40
2
11
A
PRO
0.28
0.47
0.30
7
12
A
CYS
0.46
0.64
0.42
9
13
A
LEU
0.29
0.70
0.67
5
14
A
ASP
0.28
0.32
0.65
9
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.54
10
17
A
PRO
0.54
0.47
0.40
10
18
A
ASN
0.48
0.39
0.31
3
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.43
8
22
A
TYR
0.35
0.80
0.47
5
25
A
CYS
0.50
0.64
0.28
10
27
A
PHE
0.79
1.00
0.00
10
31
A
HIS
0.33
0.60
0.60
9
32
A
LYS
0.47
0.25
0.74
3
33
A
CYS
0.77
0.64
0.58
2
34
A
LEU
0.32
0.70
0.54
3
36
A
ARG
0.38
0.51
0.40
10
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.23
10
39
A
ASN
0.40
0.39
0.37
10
40
A
CYS
1.00
0.64
0.35
10
41
A
PRO
0.76
0.47
0.59
10
42
A
LYS
0.49
0.25
0.74
10
43
A
GLY
0.89
0.41
0.59
10
44
A
LEU
0.82
0.70
0.55
10
45
A
HIS
0.56
0.60
0.40
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.42
8
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.53
10
53
A
CYS
1.00
0.64
0.39
10
54
A
ASP
0.84
0.32
0.56
10
55
A
TRP
0.64
0.99
0.73
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.63
8
65
A
ASN
0.21
0.39
0.49
10
66
A
LYS
0.17
0.25
0.68
9
67
A
GLU
0.12
0.33
0.65
9
68
A
CYS
0.20
0.64
0.58
10
70
A
LEU
0.08
0.70
0.58
8
71
A
TRP
0.06
0.99
0.56
8
72
A
LYS
0.04
0.25
0.52
10
73
A
THR
0.02
0.33
0.68
10
4
A
PHE
0.28
1.00
0.58
1
5
A
ARG
0.16
0.51
0.79
1
6
A
CYS
0.83
0.64
0.62
1
7
A
GLY
0.62
0.41
0.58
1
9
A
TYR
0.28
0.80
0.46
1
12
A
CYS
0.46
0.64
0.45
6
13
A
LEU
0.29
0.70
0.68
3
14
A
ASP
0.28
0.32
0.69
6
15
A
ASP
0.45
0.32
0.67
6
16
A
GLY
0.61
0.41
0.56
9
17
A
PRO
0.54
0.47
0.44
10
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.40
10
22
A
TYR
0.35
0.80
0.42
4
25
A
CYS
0.50
0.64
0.31
10
26
A
SER
0.58
0.36
0.09
3
27
A
PHE
0.79
1.00
0.03
10
30
A
CYS
1.00
0.64
0.41
9
31
A
HIS
0.33
0.60
0.64
6
32
A
LYS
0.47
0.25
0.77
5
33
A
CYS
0.77
0.64
0.66
4
34
A
LEU
0.32
0.70
0.59
3
36
A
ARG
0.38
0.51
0.47
9
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.29
9
39
A
ASN
0.40
0.39
0.43
10
40
A
CYS
1.00
0.64
0.40
10
41
A
PRO
0.76
0.47
0.62
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.66
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.46
10
46
A
TYR
0.76
0.80
0.21
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.43
10
49
A
TYR
0.27
0.80
0.71
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.53
9
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.44
10
54
A
ASP
0.84
0.32
0.58
10
55
A
TRP
0.64
0.99
0.76
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.80
10
58
A
LYS
0.61
0.25
0.78
10
59
A
ALA
0.72
0.38
0.54
10
60
A
GLY
0.39
0.41
0.56
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.58
10
64
A
VAL
0.26
0.56
0.59
4
66
A
LYS
0.17
0.25
0.62
4
67
A
GLU
0.12
0.33
0.65
2
68
A
CYS
0.20
0.64
0.46
4
8
A
ARG
0.25
0.51
0.37
8
9
A
TYR
0.28
0.80
0.39
1
15
A
ASP
0.45
0.32
0.60
1
16
A
GLY
0.61
0.41
0.50
1
17
A
PRO
0.54
0.47
0.40
8
19
A
VAL
0.53
0.56
0.23
8
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.47
10
24
A
CYS
0.99
0.64
0.36
10
25
A
CYS
0.50
0.64
0.27
10
34
A
LEU
0.32
0.70
0.56
1
36
A
ARG
0.38
0.51
0.44
10
37
A
LEU
0.47
0.70
0.14
10
38
A
GLU
0.51
0.33
0.26
10
39
A
ASN
0.40
0.39
0.43
10
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.78
10
43
A
GLY
0.89
0.41
0.62
10
44
A
LEU
0.82
0.70
0.59
10
47
A
ASN
0.71
0.39
0.46
10
48
A
ALA
0.45
0.38
0.44
10
49
A
TYR
0.27
0.80
0.70
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.65
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.58
10
61
A
CYS
0.95
0.64
0.53
10
62
A
THR
0.27
0.33
0.62
10
64
A
VAL
0.26
0.56
0.64
10
65
A
ASN
0.21
0.39
0.56
10
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.45
10
69
A
HIS
0.06
0.60
0.51
10
15
A
ASP
0.45
0.32
0.66
5
16
A
GLY
0.61
0.41
0.51
5
17
A
PRO
0.54
0.47
0.43
8
19
A
VAL
0.53
0.56
0.28
6
21
A
LEU
0.60
0.70
0.41
10
22
A
TYR
0.35
0.80
0.42
3
25
A
CYS
0.50
0.64
0.26
1
28
A
TYR
0.65
0.80
0.06
9
30
A
CYS
1.00
0.64
0.42
5
36
A
ARG
0.38
0.51
0.42
6
37
A
LEU
0.47
0.70
0.11
7
38
A
GLU
0.51
0.33
0.21
6
39
A
ASN
0.40
0.39
0.36
6
40
A
CYS
1.00
0.64
0.42
10
41
A
PRO
0.76
0.47
0.62
10
42
A
LYS
0.49
0.25
0.72
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.62
10
45
A
HIS
0.56
0.60
0.46
10
48
A
ALA
0.45
0.38
0.38
2
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.63
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.48
10
53
A
CYS
1.00
0.64
0.41
10
54
A
ASP
0.84
0.32
0.55
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.61
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.61
10
64
A
VAL
0.26
0.56
0.61
10
65
A
ASN
0.21
0.39
0.44
2
66
A
LYS
0.17
0.25
0.65
8
67
A
GLU
0.12
0.33
0.70
10
68
A
CYS
0.20
0.64
0.58
10
69
A
HIS
0.06
0.60
0.71
1
70
A
LEU
0.08
0.70
0.64
1
14
A
ASP
0.28
0.32
0.69
3
15
A
ASP
0.45
0.32
0.64
2
16
A
GLY
0.61
0.41
0.53
5
19
A
VAL
0.53
0.56
0.27
3
21
A
LEU
0.60
0.70
0.36
9
22
A
TYR
0.35
0.80
0.36
10
24
A
CYS
0.99
0.64
0.37
10
25
A
CYS
0.50
0.64
0.29
7
27
A
PHE
0.79
1.00
0.08
10
30
A
CYS
1.00
0.64
0.43
8
31
A
HIS
0.33
0.60
0.68
3
32
A
LYS
0.47
0.25
0.78
1
33
A
CYS
0.77
0.64
0.71
1
34
A
LEU
0.32
0.70
0.61
1
36
A
ARG
0.38
0.51
0.51
8
37
A
LEU
0.47
0.70
0.20
8
38
A
GLU
0.51
0.33
0.32
2
39
A
ASN
0.40
0.39
0.42
7
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.73
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.46
9
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.65
10
51
A
LYS
0.44
0.25
0.58
7
52
A
VAL
0.43
0.56
0.54
10
53
A
CYS
1.00
0.64
0.45
10
54
A
ASP
0.84
0.32
0.59
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.59
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.61
9
65
A
ASN
0.21
0.39
0.53
9
66
A
LYS
0.17
0.25
0.65
9
67
A
GLU
0.12
0.33
0.68
10
68
A
CYS
0.20
0.64
0.49
10
69
A
HIS
0.06
0.60
0.68
1
71
A
TRP
0.06
0.99
0.56
1
9
A
TYR
0.28
0.80
0.53
4
15
A
ASP
0.45
0.32
0.67
1
16
A
GLY
0.61
0.41
0.58
1
17
A
PRO
0.54
0.47
0.48
1
19
A
VAL
0.53
0.56
0.27
3
21
A
LEU
0.60
0.70
0.32
4
22
A
TYR
0.35
0.80
0.38
3
25
A
CYS
0.50
0.64
0.30
10
26
A
SER
0.58
0.36
0.15
6
29
A
ASN
0.39
0.39
0.44
8
31
A
HIS
0.33
0.60
0.65
4
34
A
LEU
0.32
0.70
0.67
4
36
A
ARG
0.38
0.51
0.57
10
37
A
LEU
0.47
0.70
0.26
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.49
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.69
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.43
9
48
A
ALA
0.45
0.38
0.42
5
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.64
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.48
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.48
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.59
10
65
A
ASN
0.21
0.39
0.47
8
66
A
LYS
0.17
0.25
0.63
8
67
A
GLU
0.12
0.33
0.66
5
68
A
CYS
0.20
0.64
0.51
5
69
A
HIS
0.06
0.60
0.67
4
71
A
TRP
0.06
0.99
0.58
6
9
A
TYR
0.28
0.80
0.49
2
12
A
CYS
0.46
0.64
0.43
9
13
A
LEU
0.29
0.70
0.64
5
14
A
ASP
0.28
0.32
0.66
9
15
A
ASP
0.45
0.32
0.69
9
16
A
GLY
0.61
0.41
0.57
10
17
A
PRO
0.54
0.47
0.48
10
19
A
VAL
0.53
0.56
0.26
8
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.38
10
24
A
CYS
0.99
0.64
0.32
10
25
A
CYS
0.50
0.64
0.38
10
26
A
SER
0.58
0.36
0.19
10
27
A
PHE
0.79
1.00
0.10
10
31
A
HIS
0.33
0.60
0.66
6
32
A
LYS
0.47
0.25
0.79
6
33
A
CYS
0.77
0.64
0.67
6
34
A
LEU
0.32
0.70
0.64
2
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.26
10
38
A
GLU
0.51
0.33
0.36
10
39
A
ASN
0.40
0.39
0.51
10
40
A
CYS
1.00
0.64
0.52
10
41
A
PRO
0.76
0.47
0.69
10
42
A
LYS
0.49
0.25
0.81
10
43
A
GLY
0.89
0.41
0.70
10
44
A
LEU
0.82
0.70
0.64
10
45
A
HIS
0.56
0.60
0.49
10
48
A
ALA
0.45
0.38
0.42
10
49
A
TYR
0.27
0.80
0.64
10
50
A
LEU
0.39
0.70
0.67
10
51
A
LYS
0.44
0.25
0.58
10
52
A
VAL
0.43
0.56
0.57
10
53
A
CYS
1.00
0.64
0.49
10
54
A
ASP
0.84
0.32
0.61
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.76
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.49
10
62
A
THR
0.27
0.33
0.62
10
64
A
VAL
0.26
0.56
0.60
10
66
A
LYS
0.17
0.25
0.64
8
67
A
GLU
0.12
0.33
0.68
10
68
A
CYS
0.20
0.64
0.56
10
73
A
THR
0.02
0.33
0.68
6
16
A
GLY
0.61
0.41
0.55
2
17
A
PRO
0.54
0.47
0.48
9
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.39
7
26
A
SER
0.58
0.36
0.12
3
27
A
PHE
0.79
1.00
0.08
10
30
A
CYS
1.00
0.64
0.43
2
36
A
ARG
0.38
0.51
0.52
8
37
A
LEU
0.47
0.70
0.20
9
38
A
GLU
0.51
0.33
0.33
8
39
A
ASN
0.40
0.39
0.43
9
40
A
CYS
1.00
0.64
0.45
10
41
A
PRO
0.76
0.47
0.66
10
42
A
LYS
0.49
0.25
0.77
10
43
A
GLY
0.89
0.41
0.60
10
44
A
LEU
0.82
0.70
0.58
10
45
A
HIS
0.56
0.60
0.40
7
47
A
ASN
0.71
0.39
0.50
10
48
A
ALA
0.45
0.38
0.46
9
49
A
TYR
0.27
0.80
0.72
10
50
A
LEU
0.39
0.70
0.69
10
51
A
LYS
0.44
0.25
0.59
10
52
A
VAL
0.43
0.56
0.58
10
53
A
CYS
1.00
0.64
0.50
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.64
10
57
A
SER
0.38
0.36
0.76
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.50
10
60
A
GLY
0.39
0.41
0.55
10
61
A
CYS
0.95
0.64
0.42
10
62
A
THR
0.27
0.33
0.61
10
64
A
VAL
0.26
0.56
0.59
10
65
A
ASN
0.21
0.39
0.51
10
66
A
LYS
0.17
0.25
0.64
9
67
A
GLU
0.12
0.33
0.64
1
68
A
CYS
0.20
0.64
0.54
10
71
A
TRP
0.06
0.99
0.57
8
9
A
TYR
0.28
0.80
0.47
3
12
A
CYS
0.46
0.64
0.48
9
13
A
LEU
0.29
0.70
0.69
3
14
A
ASP
0.28
0.32
0.72
9
15
A
ASP
0.45
0.32
0.66
9
16
A
GLY
0.61
0.41
0.56
10
17
A
PRO
0.54
0.47
0.49
10
18
A
ASN
0.48
0.39
0.33
1
19
A
VAL
0.53
0.56
0.27
10
21
A
LEU
0.60
0.70
0.35
9
25
A
CYS
0.50
0.64
0.37
10
27
A
PHE
0.79
1.00
0.14
10
31
A
HIS
0.33
0.60
0.69
9
32
A
LYS
0.47
0.25
0.78
9
34
A
LEU
0.32
0.70
0.64
3
36
A
ARG
0.38
0.51
0.54
10
37
A
LEU
0.47
0.70
0.29
10
38
A
GLU
0.51
0.33
0.40
10
39
A
ASN
0.40
0.39
0.46
10
40
A
CYS
1.00
0.64
0.46
10
41
A
PRO
0.76
0.47
0.65
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.67
10
44
A
LEU
0.82
0.70
0.63
10
45
A
HIS
0.56
0.60
0.46
10
47
A
ASN
0.71
0.39
0.49
10
48
A
ALA
0.45
0.38
0.44
3
49
A
TYR
0.27
0.80
0.72
10
50
A
LEU
0.39
0.70
0.68
10
51
A
LYS
0.44
0.25
0.61
10
52
A
VAL
0.43
0.56
0.56
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.60
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.66
10
57
A
SER
0.38
0.36
0.77
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.58
10
61
A
CYS
0.95
0.64
0.44
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.57
9
65
A
ASN
0.21
0.39
0.51
6
66
A
LYS
0.17
0.25
0.65
10
67
A
GLU
0.12
0.33
0.70
6
68
A
CYS
0.20
0.64
0.59
10
71
A
TRP
0.06
0.99
0.58
10
8
A
ARG
0.25
0.51
0.35
3
9
A
TYR
0.28
0.80
0.51
4
13
A
LEU
0.29
0.70
0.63
7
14
A
ASP
0.28
0.32
0.69
10
15
A
ASP
0.45
0.32
0.62
10
16
A
GLY
0.61
0.41
0.52
10
17
A
PRO
0.54
0.47
0.42
10
18
A
ASN
0.48
0.39
0.33
5
19
A
VAL
0.53
0.56
0.28
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.36
10
24
A
CYS
0.99
0.64
0.35
10
25
A
CYS
0.50
0.64
0.32
10
27
A
PHE
0.79
1.00
0.08
10
29
A
ASN
0.39
0.39
0.34
9
31
A
HIS
0.33
0.60
0.63
10
32
A
LYS
0.47
0.25
0.75
10
33
A
CYS
0.77
0.64
0.61
6
34
A
LEU
0.32
0.70
0.57
6
36
A
ARG
0.38
0.51
0.46
10
37
A
LEU
0.47
0.70
0.15
10
38
A
GLU
0.51
0.33
0.30
10
39
A
ASN
0.40
0.39
0.45
10
41
A
PRO
0.76
0.47
0.64
10
42
A
LYS
0.49
0.25
0.79
10
43
A
GLY
0.89
0.41
0.63
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.45
10
48
A
ALA
0.45
0.38
0.41
10
49
A
TYR
0.27
0.80
0.62
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.62
10
52
A
VAL
0.43
0.56
0.55
10
53
A
CYS
1.00
0.64
0.47
10
54
A
ASP
0.84
0.32
0.61
10
55
A
TRP
0.64
0.99
0.77
10
56
A
PRO
0.75
0.47
0.69
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.76
10
59
A
ALA
0.72
0.38
0.53
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.58
10
65
A
ASN
0.21
0.39
0.47
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.47
10
69
A
HIS
0.06
0.60
0.67
9
70
A
LEU
0.08
0.70
0.70
2
71
A
TRP
0.06
0.99
0.54
9
4
A
PHE
0.28
1.00
0.66
3
5
A
ARG
0.16
0.51
0.76
4
6
A
CYS
0.83
0.64
0.59
3
8
A
ARG
0.25
0.51
0.33
4
9
A
TYR
0.28
0.80
0.40
10
12
A
CYS
0.46
0.64
0.45
10
13
A
LEU
0.29
0.70
0.68
9
14
A
ASP
0.28
0.32
0.72
10
15
A
ASP
0.45
0.32
0.64
10
16
A
GLY
0.61
0.41
0.51
10
17
A
PRO
0.54
0.47
0.42
10
18
A
ASN
0.48
0.39
0.33
9
19
A
VAL
0.53
0.56
0.29
10
21
A
LEU
0.60
0.70
0.39
10
22
A
TYR
0.35
0.80
0.37
5
27
A
PHE
0.79
1.00
0.01
10
29
A
ASN
0.39
0.39
0.31
6
31
A
HIS
0.33
0.60
0.64
10
32
A
LYS
0.47
0.25
0.76
10
33
A
CYS
0.77
0.64
0.61
5
34
A
LEU
0.32
0.70
0.57
10
36
A
ARG
0.38
0.51
0.47
10
37
A
LEU
0.47
0.70
0.10
10
38
A
GLU
0.51
0.33
0.25
10
39
A
ASN
0.40
0.39
0.33
10
40
A
CYS
1.00
0.64
0.37
10
41
A
PRO
0.76
0.47
0.60
10
42
A
LYS
0.49
0.25
0.69
10
43
A
GLY
0.89
0.41
0.67
10
44
A
LEU
0.82
0.70
0.60
10
45
A
HIS
0.56
0.60
0.42
10
48
A
ALA
0.45
0.38
0.38
10
49
A
TYR
0.27
0.80
0.68
10
50
A
LEU
0.39
0.70
0.64
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.49
10
53
A
CYS
1.00
0.64
0.41
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.75
10
56
A
PRO
0.75
0.47
0.67
10
57
A
SER
0.38
0.36
0.78
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.52
10
60
A
GLY
0.39
0.41
0.62
10
61
A
CYS
0.95
0.64
0.47
10
62
A
THR
0.27
0.33
0.60
10
64
A
VAL
0.26
0.56
0.57
9
65
A
ASN
0.21
0.39
0.46
9
66
A
LYS
0.17
0.25
0.63
10
67
A
GLU
0.12
0.33
0.62
10
68
A
CYS
0.20
0.64
0.54
10
69
A
HIS
0.06
0.60
0.65
5
70
A
LEU
0.08
0.70
0.42
10
71
A
TRP
0.06
0.99
0.52
4
1
A
TYR
0.10
0.80
0.80
2
2
A
LEU
0.06
0.70
0.66
2
3
A
ALA
0.14
0.38
0.66
2
4
A
PHE
0.28
1.00
0.59
2
8
A
ARG
0.25
0.51
0.37
2
12
A
CYS
0.46
0.64
0.39
5
13
A
LEU
0.29
0.70
0.63
1
14
A
ASP
0.28
0.32
0.67
5
15
A
ASP
0.45
0.32
0.66
5
16
A
GLY
0.61
0.41
0.50
10
19
A
VAL
0.53
0.56
0.30
10
21
A
LEU
0.60
0.70
0.38
10
22
A
TYR
0.35
0.80
0.39
10
24
A
CYS
0.99
0.64
0.32
10
27
A
PHE
0.79
1.00
0.01
10
31
A
HIS
0.33
0.60
0.63
1
32
A
LYS
0.47
0.25
0.77
1
36
A
ARG
0.38
0.51
0.49
10
37
A
LEU
0.47
0.70
0.16
10
38
A
GLU
0.51
0.33
0.26
9
39
A
ASN
0.40
0.39
0.35
10
40
A
CYS
1.00
0.64
0.36
10
41
A
PRO
0.76
0.47
0.58
10
42
A
LYS
0.49
0.25
0.75
10
43
A
GLY
0.89
0.41
0.62
10
44
A
LEU
0.82
0.70
0.56
10
45
A
HIS
0.56
0.60
0.44
10
46
A
TYR
0.76
0.80
0.18
10
47
A
ASN
0.71
0.39
0.44
10
48
A
ALA
0.45
0.38
0.38
10
49
A
TYR
0.27
0.80
0.69
10
50
A
LEU
0.39
0.70
0.66
10
51
A
LYS
0.44
0.25
0.56
10
52
A
VAL
0.43
0.56
0.52
10
53
A
CYS
1.00
0.64
0.40
10
54
A
ASP
0.84
0.32
0.57
10
55
A
TRP
0.64
0.99
0.74
10
56
A
PRO
0.75
0.47
0.68
10
57
A
SER
0.38
0.36
0.79
10
58
A
LYS
0.61
0.25
0.77
10
59
A
ALA
0.72
0.38
0.51
10
60
A
GLY
0.39
0.41
0.57
10
61
A
CYS
0.95
0.64
0.44
10
62
A
THR
0.27
0.33
0.57
10
64
A
VAL
0.26
0.56
0.59
9
65
A
ASN
0.21
0.39
0.44
10
66
A
LYS
0.17
0.25
0.64
10
67
A
GLU
0.12
0.33
0.56
10
68
A
CYS
0.20
0.64
0.53
10
69
A
HIS
0.06
0.60
0.66
6
70
A
LEU
0.08
0.70
0.70
3
71
A
TRP
0.06
0.99
0.48
8