Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DRS chain A sc3

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
ARG
0.23
0.51
0.57
10
2
A
ILE
0.61
0.64
0.56
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.79
10
11
A
PRO
0.77
0.47
0.69
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.56
10
18
A
GLN
0.48
0.43
0.76
10
20
A
ASP
0.66
0.32
0.70
10
27
A
TRP
1.00
0.99
0.52
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.38
10
39
A
CYS
1.00
0.64
0.42
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.62
10
42
A
PRO
0.90
0.47
0.75
10
43
A
ARG
0.93
0.51
0.62
10
44
A
GLY
0.64
0.41
0.79
10
45
A
ASP
0.91
0.32
0.78
10
46
A
MET
0.62
0.66
0.78
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.40
10
52
A
CYS
1.00
0.64
0.44
10
57
A
CYS
0.99
0.64
0.49
10
59
A
LEU
0.00
0.70
0.56
10
1
A
ARG
0.23
0.51
0.60
10
2
A
ILE
0.61
0.64
0.52
10
7
A
LEU
0.83
0.70
0.50
10
8
A
GLY
0.90
0.41
0.59
10
9
A
THR
0.84
0.33
0.76
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.77
10
12
A
PRO
0.71
0.47
0.68
10
17
A
CYS
0.96
0.64
0.52
10
18
A
GLN
0.48
0.43
0.73
10
19
A
GLU
0.71
0.33
0.59
10
20
A
ASP
0.66
0.32
0.64
10
26
A
ILE
0.57
0.64
0.42
10
27
A
TRP
1.00
0.99
0.51
10
29
A
PHE
0.80
1.00
0.75
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.71
10
32
A
ILE
0.42
0.64
0.50
10
33
A
ILE
0.71
0.64
0.32
10
39
A
CYS
1.00
0.64
0.35
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.55
10
42
A
PRO
0.90
0.47
0.74
10
43
A
ARG
0.93
0.51
0.67
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.87
10
46
A
MET
0.62
0.66
0.76
10
47
A
PRO
0.50
0.47
0.71
10
48
A
GLY
0.11
0.41
0.51
10
50
A
TYR
0.46
0.80
0.39
10
51
A
CYS
1.00
0.64
0.35
10
52
A
CYS
1.00
0.64
0.39
10
53
A
GLU
0.40
0.33
0.63
10
57
A
CYS
0.99
0.64
0.51
10
59
A
LEU
0.00
0.70
0.50
10
2
A
ILE
0.61
0.64
0.57
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.76
10
19
A
GLU
0.71
0.33
0.61
10
20
A
ASP
0.66
0.32
0.63
10
26
A
ILE
0.57
0.64
0.47
10
27
A
TRP
1.00
0.99
0.55
10
29
A
PHE
0.80
1.00
0.79
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.55
10
33
A
ILE
0.71
0.64
0.41
10
39
A
CYS
1.00
0.64
0.39
10
40
A
PHE
0.98
1.00
0.61
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.75
10
43
A
ARG
0.93
0.51
0.81
10
44
A
GLY
0.64
0.41
0.84
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.74
10
47
A
PRO
0.50
0.47
0.68
10
50
A
TYR
0.46
0.80
0.43
10
51
A
CYS
1.00
0.64
0.38
10
52
A
CYS
1.00
0.64
0.42
10
53
A
GLU
0.40
0.33
0.61
10
59
A
LEU
0.00
0.70
0.47
10
7
A
LEU
0.83
0.70
0.52
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.78
10
11
A
PRO
0.77
0.47
0.70
10
12
A
PRO
0.71
0.47
0.74
10
18
A
GLN
0.48
0.43
0.74
10
20
A
ASP
0.66
0.32
0.69
10
26
A
ILE
0.57
0.64
0.43
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.73
10
32
A
ILE
0.42
0.64
0.53
10
33
A
ILE
0.71
0.64
0.36
10
40
A
PHE
0.98
1.00
0.61
10
41
A
THR
0.42
0.33
0.58
10
42
A
PRO
0.90
0.47
0.73
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.74
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.51
10
50
A
TYR
0.46
0.80
0.44
10
51
A
CYS
1.00
0.64
0.40
10
52
A
CYS
1.00
0.64
0.44
10
53
A
GLU
0.40
0.33
0.64
10
57
A
CYS
0.99
0.64
0.50
10
58
A
ASN
0.96
0.39
0.59
10
59
A
LEU
0.00
0.70
0.52
10
2
A
ILE
0.61
0.64
0.55
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.52
10
8
A
GLY
0.90
0.41
0.62
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.72
10
11
A
PRO
0.77
0.47
0.79
10
12
A
PRO
0.71
0.47
0.72
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.72
10
19
A
GLU
0.71
0.33
0.55
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.44
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.65
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.52
10
33
A
ILE
0.71
0.64
0.39
10
39
A
CYS
1.00
0.64
0.39
10
40
A
PHE
0.98
1.00
0.63
10
41
A
THR
0.42
0.33
0.58
10
42
A
PRO
0.90
0.47
0.73
10
43
A
ARG
0.93
0.51
0.80
10
44
A
GLY
0.64
0.41
0.79
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.72
10
47
A
PRO
0.50
0.47
0.70
10
48
A
GLY
0.11
0.41
0.51
10
50
A
TYR
0.46
0.80
0.43
10
51
A
CYS
1.00
0.64
0.39
10
57
A
CYS
0.99
0.64
0.57
10
59
A
LEU
0.00
0.70
0.52
10
1
A
ARG
0.23
0.51
0.66
10
2
A
ILE
0.61
0.64
0.60
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.64
10
11
A
PRO
0.77
0.47
0.70
10
12
A
PRO
0.71
0.47
0.76
10
16
A
THR
0.33
0.33
0.69
10
17
A
CYS
0.96
0.64
0.57
10
18
A
GLN
0.48
0.43
0.73
10
20
A
ASP
0.66
0.32
0.71
10
26
A
ILE
0.57
0.64
0.52
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.78
10
30
A
ASP
0.93
0.32
0.67
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.45
10
39
A
CYS
1.00
0.64
0.48
10
40
A
PHE
0.98
1.00
0.68
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.80
10
44
A
GLY
0.64
0.41
0.78
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.71
10
47
A
PRO
0.50
0.47
0.68
10
48
A
GLY
0.11
0.41
0.55
10
50
A
TYR
0.46
0.80
0.54
10
51
A
CYS
1.00
0.64
0.53
10
52
A
CYS
1.00
0.64
0.54
10
53
A
GLU
0.40
0.33
0.73
10
54
A
SER
0.76
0.36
0.66
10
55
A
ASP
0.67
0.32
0.70
10
57
A
CYS
0.99
0.64
0.56
10
59
A
LEU
0.00
0.70
0.53
10
1
A
ARG
0.23
0.51
0.60
10
4
A
TYR
0.67
0.80
0.30
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.51
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.73
10
11
A
PRO
0.77
0.47
0.79
10
12
A
PRO
0.71
0.47
0.69
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.76
10
19
A
GLU
0.71
0.33
0.61
10
20
A
ASP
0.66
0.32
0.68
10
26
A
ILE
0.57
0.64
0.42
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.80
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.55
10
39
A
CYS
1.00
0.64
0.42
10
40
A
PHE
0.98
1.00
0.66
10
41
A
THR
0.42
0.33
0.60
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.64
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.79
10
46
A
MET
0.62
0.66
0.79
10
47
A
PRO
0.50
0.47
0.72
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.42
10
51
A
CYS
1.00
0.64
0.39
10
52
A
CYS
1.00
0.64
0.43
10
53
A
GLU
0.40
0.33
0.67
10
57
A
CYS
0.99
0.64
0.53
10
59
A
LEU
0.00
0.70
0.56
10
1
A
ARG
0.23
0.51
0.64
10
2
A
ILE
0.61
0.64
0.59
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.55
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.81
10
10
A
LYS
0.71
0.25
0.73
10
11
A
PRO
0.77
0.47
0.78
10
12
A
PRO
0.71
0.47
0.71
10
16
A
THR
0.33
0.33
0.68
10
18
A
GLN
0.48
0.43
0.75
10
19
A
GLU
0.71
0.33
0.63
10
20
A
ASP
0.66
0.32
0.70
10
26
A
ILE
0.57
0.64
0.47
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.71
10
30
A
ASP
0.93
0.32
0.68
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.41
10
39
A
CYS
1.00
0.64
0.41
10
40
A
PHE
0.98
1.00
0.64
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.76
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.86
10
46
A
MET
0.62
0.66
0.76
10
47
A
PRO
0.50
0.47
0.70
10
48
A
GLY
0.11
0.41
0.53
10
51
A
CYS
1.00
0.64
0.44
10
52
A
CYS
1.00
0.64
0.48
10
53
A
GLU
0.40
0.33
0.67
10
54
A
SER
0.76
0.36
0.66
10
55
A
ASP
0.67
0.32
0.68
10
57
A
CYS
0.99
0.64
0.61
10
2
A
ILE
0.61
0.64
0.54
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.55
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.79
10
12
A
PRO
0.71
0.47
0.70
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.60
10
20
A
ASP
0.66
0.32
0.69
10
26
A
ILE
0.57
0.64
0.45
10
27
A
TRP
1.00
0.99
0.52
10
29
A
PHE
0.80
1.00
0.71
10
30
A
ASP
0.93
0.32
0.66
10
31
A
ASN
0.73
0.39
0.73
10
32
A
ILE
0.42
0.64
0.52
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.75
10
43
A
ARG
0.93
0.51
0.84
10
44
A
GLY
0.64
0.41
0.78
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.73
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.45
10
51
A
CYS
1.00
0.64
0.39
10
52
A
CYS
1.00
0.64
0.43
10
53
A
GLU
0.40
0.33
0.65
10
57
A
CYS
0.99
0.64
0.52
10
59
A
LEU
0.00
0.70
0.54
10
2
A
ILE
0.61
0.64
0.57
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.64
10
11
A
PRO
0.77
0.47
0.73
10
12
A
PRO
0.71
0.47
0.75
10
20
A
ASP
0.66
0.32
0.64
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.57
10
29
A
PHE
0.80
1.00
0.78
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.38
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.63
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.73
10
43
A
ARG
0.93
0.51
0.82
10
44
A
GLY
0.64
0.41
0.85
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.74
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.46
10
51
A
CYS
1.00
0.64
0.41
10
52
A
CYS
1.00
0.64
0.45
10
53
A
GLU
0.40
0.33
0.66
10
54
A
SER
0.76
0.36
0.64
10
55
A
ASP
0.67
0.32
0.67
10
57
A
CYS
0.99
0.64
0.52
10
58
A
ASN
0.96
0.39
0.58
10
59
A
LEU
0.00
0.70
0.48
10
1
A
ARG
0.23
0.51
0.61
10
2
A
ILE
0.61
0.64
0.53
10
4
A
TYR
0.67
0.80
0.33
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.61
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.78
10
12
A
PRO
0.71
0.47
0.70
10
16
A
THR
0.33
0.33
0.66
10
17
A
CYS
0.96
0.64
0.57
10
18
A
GLN
0.48
0.43
0.75
10
19
A
GLU
0.71
0.33
0.62
10
20
A
ASP
0.66
0.32
0.68
10
26
A
ILE
0.57
0.64
0.43
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.54
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.65
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.63
10
44
A
GLY
0.64
0.41
0.79
10
45
A
ASP
0.91
0.32
0.76
10
46
A
MET
0.62
0.66
0.79
10
47
A
PRO
0.50
0.47
0.72
10
50
A
TYR
0.46
0.80
0.41
10
51
A
CYS
1.00
0.64
0.38
10
52
A
CYS
1.00
0.64
0.45
10
53
A
GLU
0.40
0.33
0.65
10
54
A
SER
0.76
0.36
0.64
10
57
A
CYS
0.99
0.64
0.55
10
58
A
ASN
0.96
0.39
0.63
10
59
A
LEU
0.00
0.70
0.54
10
1
A
ARG
0.23
0.51
0.58
10
2
A
ILE
0.61
0.64
0.59
10
6
A
HIS
0.73
0.60
0.51
10
7
A
LEU
0.83
0.70
0.49
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.79
10
11
A
PRO
0.77
0.47
0.76
10
12
A
PRO
0.71
0.47
0.75
10
16
A
THR
0.33
0.33
0.68
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.76
10
20
A
ASP
0.66
0.32
0.64
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.55
10
29
A
PHE
0.80
1.00
0.71
10
30
A
ASP
0.93
0.32
0.68
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.53
10
33
A
ILE
0.71
0.64
0.37
10
39
A
CYS
1.00
0.64
0.39
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.57
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.78
10
44
A
GLY
0.64
0.41
0.84
10
45
A
ASP
0.91
0.32
0.86
10
46
A
MET
0.62
0.66
0.77
10
47
A
PRO
0.50
0.47
0.71
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.46
10
52
A
CYS
1.00
0.64
0.44
10
53
A
GLU
0.40
0.33
0.64
10
57
A
CYS
0.99
0.64
0.55
10
1
A
ARG
0.23
0.51
0.64
10
2
A
ILE
0.61
0.64
0.59
10
4
A
TYR
0.67
0.80
0.35
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.77
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.75
10
17
A
CYS
0.96
0.64
0.58
10
18
A
GLN
0.48
0.43
0.77
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.47
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.74
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.55
10
33
A
ILE
0.71
0.64
0.40
10
40
A
PHE
0.98
1.00
0.66
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.80
10
44
A
GLY
0.64
0.41
0.78
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.70
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.50
10
51
A
CYS
1.00
0.64
0.47
10
52
A
CYS
1.00
0.64
0.51
10
53
A
GLU
0.40
0.33
0.70
10
57
A
CYS
0.99
0.64
0.54
10
2
A
ILE
0.61
0.64
0.58
10
7
A
LEU
0.83
0.70
0.52
10
8
A
GLY
0.90
0.41
0.64
10
11
A
PRO
0.77
0.47
0.73
10
17
A
CYS
0.96
0.64
0.57
10
18
A
GLN
0.48
0.43
0.75
10
19
A
GLU
0.71
0.33
0.59
10
20
A
ASP
0.66
0.32
0.70
10
26
A
ILE
0.57
0.64
0.49
10
27
A
TRP
1.00
0.99
0.56
10
28
A
THR
0.64
0.33
0.56
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.75
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.41
10
39
A
CYS
1.00
0.64
0.44
10
40
A
PHE
0.98
1.00
0.66
10
42
A
PRO
0.90
0.47
0.74
10
43
A
ARG
0.93
0.51
0.76
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.68
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.56
10
50
A
TYR
0.46
0.80
0.52
10
51
A
CYS
1.00
0.64
0.49
10
52
A
CYS
1.00
0.64
0.50
10
53
A
GLU
0.40
0.33
0.69
10
54
A
SER
0.76
0.36
0.66
10
57
A
CYS
0.99
0.64
0.60
10
59
A
LEU
0.00
0.70
0.52
10
1
A
ARG
0.23
0.51
0.63
10
2
A
ILE
0.61
0.64
0.54
10
6
A
HIS
0.73
0.60
0.46
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.73
10
11
A
PRO
0.77
0.47
0.76
10
12
A
PRO
0.71
0.47
0.66
10
17
A
CYS
0.96
0.64
0.53
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.60
10
20
A
ASP
0.66
0.32
0.64
10
26
A
ILE
0.57
0.64
0.41
10
27
A
TRP
1.00
0.99
0.49
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.35
10
39
A
CYS
1.00
0.64
0.37
10
40
A
PHE
0.98
1.00
0.64
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.68
10
44
A
GLY
0.64
0.41
0.81
10
45
A
ASP
0.91
0.32
0.81
10
46
A
MET
0.62
0.66
0.77
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.49
10
50
A
TYR
0.46
0.80
0.40
10
51
A
CYS
1.00
0.64
0.37
10
52
A
CYS
1.00
0.64
0.42
10
53
A
GLU
0.40
0.33
0.65
10
57
A
CYS
0.99
0.64
0.52
10
58
A
ASN
0.96
0.39
0.64
10
59
A
LEU
0.00
0.70
0.49
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.65
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.58
10
20
A
ASP
0.66
0.32
0.65
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.57
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.72
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.34
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.60
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.81
10
44
A
GLY
0.64
0.41
0.77
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.73
10
47
A
PRO
0.50
0.47
0.69
10
50
A
TYR
0.46
0.80
0.48
10
51
A
CYS
1.00
0.64
0.42
10
52
A
CYS
1.00
0.64
0.45
10
54
A
SER
0.76
0.36
0.66
10
57
A
CYS
0.99
0.64
0.51
10
58
A
ASN
0.96
0.39
0.64
10
59
A
LEU
0.00
0.70
0.48
10
4
A
TYR
0.67
0.80
0.31
10
6
A
HIS
0.73
0.60
0.50
10
7
A
LEU
0.83
0.70
0.51
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.69
10
12
A
PRO
0.71
0.47
0.73
10
18
A
GLN
0.48
0.43
0.71
10
20
A
ASP
0.66
0.32
0.65
10
26
A
ILE
0.57
0.64
0.47
10
27
A
TRP
1.00
0.99
0.55
10
29
A
PHE
0.80
1.00
0.78
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.73
10
32
A
ILE
0.42
0.64
0.55
10
33
A
ILE
0.71
0.64
0.37
10
39
A
CYS
1.00
0.64
0.41
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.57
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.81
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.69
10
47
A
PRO
0.50
0.47
0.67
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.48
10
51
A
CYS
1.00
0.64
0.45
10
52
A
CYS
1.00
0.64
0.46
10
53
A
GLU
0.40
0.33
0.66
10
59
A
LEU
0.00
0.70
0.53
10
1
A
ARG
0.23
0.51
0.62
10
2
A
ILE
0.61
0.64
0.57
10
7
A
LEU
0.83
0.70
0.56
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.80
10
11
A
PRO
0.77
0.47
0.79
10
12
A
PRO
0.71
0.47
0.75
10
18
A
GLN
0.48
0.43
0.78
10
20
A
ASP
0.66
0.32
0.72
10
26
A
ILE
0.57
0.64
0.55
10
27
A
TRP
1.00
0.99
0.59
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.67
10
31
A
ASN
0.73
0.39
0.75
10
32
A
ILE
0.42
0.64
0.57
10
33
A
ILE
0.71
0.64
0.49
10
39
A
CYS
1.00
0.64
0.44
10
40
A
PHE
0.98
1.00
0.65
10
42
A
PRO
0.90
0.47
0.79
10
43
A
ARG
0.93
0.51
0.77
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.83
10
46
A
MET
0.62
0.66
0.62
10
47
A
PRO
0.50
0.47
0.65
10
48
A
GLY
0.11
0.41
0.58
10
50
A
TYR
0.46
0.80
0.55
10
52
A
CYS
1.00
0.64
0.55
10
53
A
GLU
0.40
0.33
0.73
10
57
A
CYS
0.99
0.64
0.66
10
58
A
ASN
0.96
0.39
0.63
10
59
A
LEU
0.00
0.70
0.60
10
1
A
ARG
0.23
0.51
0.67
10
2
A
ILE
0.61
0.64
0.59
10
4
A
TYR
0.67
0.80
0.40
10
6
A
HIS
0.73
0.60
0.52
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.62
10
9
A
THR
0.84
0.33
0.77
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.76
10
17
A
CYS
0.96
0.64
0.56
10
18
A
GLN
0.48
0.43
0.77
10
26
A
ILE
0.57
0.64
0.50
10
27
A
TRP
1.00
0.99
0.57
10
29
A
PHE
0.80
1.00
0.79
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.56
10
39
A
CYS
1.00
0.64
0.44
10
40
A
PHE
0.98
1.00
0.66
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.77
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.72
10
47
A
PRO
0.50
0.47
0.64
10
48
A
GLY
0.11
0.41
0.55
10
50
A
TYR
0.46
0.80
0.53
10
51
A
CYS
1.00
0.64
0.49
10
52
A
CYS
1.00
0.64
0.52
10
57
A
CYS
0.99
0.64
0.57
10
59
A
LEU
0.00
0.70
0.54
10
1
A
ARG
0.23
0.51
0.57
10
2
A
ILE
0.61
0.64
0.54
10
4
A
TYR
0.67
0.80
0.33
10
6
A
HIS
0.73
0.60
0.48
10
7
A
LEU
0.83
0.70
0.51
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.77
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.69
10
12
A
PRO
0.71
0.47
0.73
10
17
A
CYS
0.96
0.64
0.52
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.61
10
20
A
ASP
0.66
0.32
0.64
10
26
A
ILE
0.57
0.64
0.44
10
27
A
TRP
1.00
0.99
0.55
10
28
A
THR
0.64
0.33
0.55
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.38
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.66
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.66
10
46
A
MET
0.62
0.66
0.80
10
47
A
PRO
0.50
0.47
0.75
10
48
A
GLY
0.11
0.41
0.55
10
50
A
TYR
0.46
0.80
0.38
10
52
A
CYS
1.00
0.64
0.39
10
53
A
GLU
0.40
0.33
0.61
10
57
A
CYS
0.99
0.64
0.47
10
59
A
LEU
0.00
0.70
0.45
10
1
A
ARG
0.23
0.51
0.63
10
2
A
ILE
0.61
0.64
0.59
10
6
A
HIS
0.73
0.60
0.48
10
7
A
LEU
0.83
0.70
0.54
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.76
10
10
A
LYS
0.71
0.25
0.76
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.73
10
17
A
CYS
0.96
0.64
0.55
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.64
10
20
A
ASP
0.66
0.32
0.66
10
26
A
ILE
0.57
0.64
0.45
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.74
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.75
10
32
A
ILE
0.42
0.64
0.55
10
39
A
CYS
1.00
0.64
0.38
10
40
A
PHE
0.98
1.00
0.63
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.77
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.86
10
46
A
MET
0.62
0.66
0.72
10
47
A
PRO
0.50
0.47
0.71
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.46
10
51
A
CYS
1.00
0.64
0.44
10
52
A
CYS
1.00
0.64
0.43
10
57
A
CYS
0.99
0.64
0.44
10
59
A
LEU
0.00
0.70
0.56
10
1
A
ARG
0.23
0.51
0.65
10
2
A
ILE
0.61
0.64
0.57
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.61
10
9
A
THR
0.84
0.33
0.76
10
10
A
LYS
0.71
0.25
0.76
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.74
10
16
A
THR
0.33
0.33
0.68
10
17
A
CYS
0.96
0.64
0.57
10
18
A
GLN
0.48
0.43
0.75
10
20
A
ASP
0.66
0.32
0.67
10
27
A
TRP
1.00
0.99
0.52
10
29
A
PHE
0.80
1.00
0.80
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.71
10
32
A
ILE
0.42
0.64
0.52
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.65
10
42
A
PRO
0.90
0.47
0.75
10
43
A
ARG
0.93
0.51
0.65
10
44
A
GLY
0.64
0.41
0.79
10
45
A
ASP
0.91
0.32
0.80
10
46
A
MET
0.62
0.66
0.79
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.43
10
51
A
CYS
1.00
0.64
0.40
10
52
A
CYS
1.00
0.64
0.43
10
53
A
GLU
0.40
0.33
0.65
10
59
A
LEU
0.00
0.70
0.49
10
2
A
ILE
0.61
0.64
0.62
10
6
A
HIS
0.73
0.60
0.51
10
7
A
LEU
0.83
0.70
0.57
10
8
A
GLY
0.90
0.41
0.66
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.77
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.75
10
17
A
CYS
0.96
0.64
0.55
10
18
A
GLN
0.48
0.43
0.76
10
20
A
ASP
0.66
0.32
0.66
10
26
A
ILE
0.57
0.64
0.49
10
27
A
TRP
1.00
0.99
0.55
10
29
A
PHE
0.80
1.00
0.78
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.76
10
32
A
ILE
0.42
0.64
0.58
10
33
A
ILE
0.71
0.64
0.45
10
40
A
PHE
0.98
1.00
0.65
10
41
A
THR
0.42
0.33
0.62
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.73
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.76
10
47
A
PRO
0.50
0.47
0.65
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.53
10
51
A
CYS
1.00
0.64
0.45
10
52
A
CYS
1.00
0.64
0.48
10
53
A
GLU
0.40
0.33
0.68
10
57
A
CYS
0.99
0.64
0.61
10
59
A
LEU
0.00
0.70
0.47
10
1
A
ARG
0.23
0.51
0.66
10
2
A
ILE
0.61
0.64
0.61
10
4
A
TYR
0.67
0.80
0.37
10
6
A
HIS
0.73
0.60
0.47
10
7
A
LEU
0.83
0.70
0.57
10
8
A
GLY
0.90
0.41
0.65
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.56
10
18
A
GLN
0.48
0.43
0.75
10
20
A
ASP
0.66
0.32
0.71
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.57
10
29
A
PHE
0.80
1.00
0.79
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.76
10
32
A
ILE
0.42
0.64
0.58
10
33
A
ILE
0.71
0.64
0.42
10
39
A
CYS
1.00
0.64
0.46
10
40
A
PHE
0.98
1.00
0.67
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.84
10
44
A
GLY
0.64
0.41
0.75
10
45
A
ASP
0.91
0.32
0.82
10
46
A
MET
0.62
0.66
0.70
10
47
A
PRO
0.50
0.47
0.70
10
48
A
GLY
0.11
0.41
0.57
10
50
A
TYR
0.46
0.80
0.54
10
51
A
CYS
1.00
0.64
0.55
10
52
A
CYS
1.00
0.64
0.52
10
53
A
GLU
0.40
0.33
0.71
10
54
A
SER
0.76
0.36
0.65
10
55
A
ASP
0.67
0.32
0.67
10
57
A
CYS
0.99
0.64
0.54
10
58
A
ASN
0.96
0.39
0.67
10
59
A
LEU
0.00
0.70
0.48
10
2
A
ILE
0.61
0.64
0.59
10
7
A
LEU
0.83
0.70
0.51
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.79
10
11
A
PRO
0.77
0.47
0.68
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.55
10
19
A
GLU
0.71
0.33
0.60
10
20
A
ASP
0.66
0.32
0.63
10
26
A
ILE
0.57
0.64
0.44
10
27
A
TRP
1.00
0.99
0.52
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.71
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.36
10
39
A
CYS
1.00
0.64
0.42
10
40
A
PHE
0.98
1.00
0.63
10
41
A
THR
0.42
0.33
0.61
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.81
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.72
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.44
10
51
A
CYS
1.00
0.64
0.41
10
52
A
CYS
1.00
0.64
0.40
10
53
A
GLU
0.40
0.33
0.64
10
58
A
ASN
0.96
0.39
0.63
10
59
A
LEU
0.00
0.70
0.58
10
1
A
ARG
0.23
0.51
0.63
10
2
A
ILE
0.61
0.64
0.55
10
6
A
HIS
0.73
0.60
0.53
10
7
A
LEU
0.83
0.70
0.49
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.79
10
11
A
PRO
0.77
0.47
0.69
10
12
A
PRO
0.71
0.47
0.74
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.74
10
20
A
ASP
0.66
0.32
0.66
10
26
A
ILE
0.57
0.64
0.45
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.75
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.52
10
39
A
CYS
1.00
0.64
0.44
10
40
A
PHE
0.98
1.00
0.66
10
41
A
THR
0.42
0.33
0.61
10
42
A
PRO
0.90
0.47
0.78
10
43
A
ARG
0.93
0.51
0.76
10
44
A
GLY
0.64
0.41
0.81
10
45
A
ASP
0.91
0.32
0.83
10
46
A
MET
0.62
0.66
0.73
10
47
A
PRO
0.50
0.47
0.64
10
50
A
TYR
0.46
0.80
0.46
10
51
A
CYS
1.00
0.64
0.46
10
52
A
CYS
1.00
0.64
0.47
10
53
A
GLU
0.40
0.33
0.69
10
57
A
CYS
0.99
0.64
0.51
10
59
A
LEU
0.00
0.70
0.56
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.57
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.77
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.74
10
20
A
ASP
0.66
0.32
0.65
10
26
A
ILE
0.57
0.64
0.46
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.75
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.42
10
39
A
CYS
1.00
0.64
0.41
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.58
10
42
A
PRO
0.90
0.47
0.71
10
43
A
ARG
0.93
0.51
0.85
10
44
A
GLY
0.64
0.41
0.81
10
45
A
ASP
0.91
0.32
0.83
10
46
A
MET
0.62
0.66
0.70
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.51
10
50
A
TYR
0.46
0.80
0.50
10
51
A
CYS
1.00
0.64
0.44
10
52
A
CYS
1.00
0.64
0.50
10
57
A
CYS
0.99
0.64
0.56
10
1
A
ARG
0.23
0.51
0.64
10
2
A
ILE
0.61
0.64
0.57
10
4
A
TYR
0.67
0.80
0.34
10
6
A
HIS
0.73
0.60
0.47
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.62
10
9
A
THR
0.84
0.33
0.77
10
10
A
LYS
0.71
0.25
0.77
10
11
A
PRO
0.77
0.47
0.70
10
12
A
PRO
0.71
0.47
0.73
10
17
A
CYS
0.96
0.64
0.55
10
18
A
GLN
0.48
0.43
0.73
10
20
A
ASP
0.66
0.32
0.70
10
26
A
ILE
0.57
0.64
0.46
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.79
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.72
10
32
A
ILE
0.42
0.64
0.54
10
39
A
CYS
1.00
0.64
0.45
10
40
A
PHE
0.98
1.00
0.65
10
42
A
PRO
0.90
0.47
0.71
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.75
10
45
A
ASP
0.91
0.32
0.83
10
46
A
MET
0.62
0.66
0.71
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.49
10
51
A
CYS
1.00
0.64
0.49
10
52
A
CYS
1.00
0.64
0.50
10
53
A
GLU
0.40
0.33
0.70
10
57
A
CYS
0.99
0.64
0.54
10
58
A
ASN
0.96
0.39
0.68
10
59
A
LEU
0.00
0.70
0.54
10
2
A
ILE
0.61
0.64
0.54
10
4
A
TYR
0.67
0.80
0.32
10
6
A
HIS
0.73
0.60
0.48
10
7
A
LEU
0.83
0.70
0.47
10
8
A
GLY
0.90
0.41
0.62
10
11
A
PRO
0.77
0.47
0.68
10
12
A
PRO
0.71
0.47
0.72
10
17
A
CYS
0.96
0.64
0.53
10
18
A
GLN
0.48
0.43
0.74
10
20
A
ASP
0.66
0.32
0.65
10
26
A
ILE
0.57
0.64
0.47
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.80
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.71
10
32
A
ILE
0.42
0.64
0.52
10
33
A
ILE
0.71
0.64
0.33
10
39
A
CYS
1.00
0.64
0.38
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.84
10
44
A
GLY
0.64
0.41
0.74
10
45
A
ASP
0.91
0.32
0.81
10
46
A
MET
0.62
0.66
0.66
10
47
A
PRO
0.50
0.47
0.64
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.42
10
51
A
CYS
1.00
0.64
0.39
10
55
A
ASP
0.67
0.32
0.64
10
57
A
CYS
0.99
0.64
0.51
10
58
A
ASN
0.96
0.39
0.66
10
59
A
LEU
0.00
0.70
0.53
10
2
A
ILE
0.61
0.64
0.59
10
7
A
LEU
0.83
0.70
0.56
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.62
10
20
A
ASP
0.66
0.32
0.65
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.72
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.75
10
32
A
ILE
0.42
0.64
0.57
10
33
A
ILE
0.71
0.64
0.44
10
39
A
CYS
1.00
0.64
0.41
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.60
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.84
10
45
A
ASP
0.91
0.32
0.86
10
46
A
MET
0.62
0.66
0.71
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.50
10
51
A
CYS
1.00
0.64
0.44
10
52
A
CYS
1.00
0.64
0.44
10
53
A
GLU
0.40
0.33
0.65
10
7
A
LEU
0.83
0.70
0.56
10
8
A
GLY
0.90
0.41
0.66
10
9
A
THR
0.84
0.33
0.77
10
11
A
PRO
0.77
0.47
0.73
10
12
A
PRO
0.71
0.47
0.76
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.66
10
20
A
ASP
0.66
0.32
0.69
10
26
A
ILE
0.57
0.64
0.44
10
27
A
TRP
1.00
0.99
0.54
10
28
A
THR
0.64
0.33
0.57
10
29
A
PHE
0.80
1.00
0.78
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.38
10
39
A
CYS
1.00
0.64
0.36
10
40
A
PHE
0.98
1.00
0.60
10
41
A
THR
0.42
0.33
0.54
10
42
A
PRO
0.90
0.47
0.71
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.81
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.74
10
47
A
PRO
0.50
0.47
0.68
10
48
A
GLY
0.11
0.41
0.49
10
50
A
TYR
0.46
0.80
0.44
10
51
A
CYS
1.00
0.64
0.39
10
52
A
CYS
1.00
0.64
0.46
10
53
A
GLU
0.40
0.33
0.67
10
57
A
CYS
0.99
0.64
0.54
10
58
A
ASN
0.96
0.39
0.56
10
59
A
LEU
0.00
0.70
0.53
10
1
A
ARG
0.23
0.51
0.63
10
2
A
ILE
0.61
0.64
0.54
10
4
A
TYR
0.67
0.80
0.38
10
6
A
HIS
0.73
0.60
0.53
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.66
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.80
10
11
A
PRO
0.77
0.47
0.70
10
12
A
PRO
0.71
0.47
0.75
10
17
A
CYS
0.96
0.64
0.55
10
18
A
GLN
0.48
0.43
0.73
10
20
A
ASP
0.66
0.32
0.68
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.73
10
32
A
ILE
0.42
0.64
0.57
10
33
A
ILE
0.71
0.64
0.42
10
39
A
CYS
1.00
0.64
0.45
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.60
10
42
A
PRO
0.90
0.47
0.73
10
43
A
ARG
0.93
0.51
0.84
10
44
A
GLY
0.64
0.41
0.82
10
45
A
ASP
0.91
0.32
0.82
10
46
A
MET
0.62
0.66
0.66
10
48
A
GLY
0.11
0.41
0.55
10
50
A
TYR
0.46
0.80
0.49
10
51
A
CYS
1.00
0.64
0.49
10
52
A
CYS
1.00
0.64
0.48
10
53
A
GLU
0.40
0.33
0.66
10
57
A
CYS
0.99
0.64
0.56
10
59
A
LEU
0.00
0.70
0.63
10
2
A
ILE
0.61
0.64
0.59
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.58
10
8
A
GLY
0.90
0.41
0.66
10
11
A
PRO
0.77
0.47
0.78
10
12
A
PRO
0.71
0.47
0.71
10
18
A
GLN
0.48
0.43
0.73
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.50
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.75
10
30
A
ASP
0.93
0.32
0.72
10
31
A
ASN
0.73
0.39
0.77
10
32
A
ILE
0.42
0.64
0.59
10
33
A
ILE
0.71
0.64
0.46
10
40
A
PHE
0.98
1.00
0.64
10
42
A
PRO
0.90
0.47
0.78
10
43
A
ARG
0.93
0.51
0.78
10
44
A
GLY
0.64
0.41
0.82
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.66
10
47
A
PRO
0.50
0.47
0.67
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.52
10
52
A
CYS
1.00
0.64
0.47
10
54
A
SER
0.76
0.36
0.66
10
55
A
ASP
0.67
0.32
0.69
10
57
A
CYS
0.99
0.64
0.60
10
58
A
ASN
0.96
0.39
0.71
10
59
A
LEU
0.00
0.70
0.60
10
2
A
ILE
0.61
0.64
0.56
10
4
A
TYR
0.67
0.80
0.35
10
6
A
HIS
0.73
0.60
0.52
10
7
A
LEU
0.83
0.70
0.49
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.79
10
11
A
PRO
0.77
0.47
0.73
10
12
A
PRO
0.71
0.47
0.75
10
17
A
CYS
0.96
0.64
0.54
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.58
10
20
A
ASP
0.66
0.32
0.68
10
26
A
ILE
0.57
0.64
0.49
10
27
A
TRP
1.00
0.99
0.56
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.69
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.55
10
33
A
ILE
0.71
0.64
0.40
10
39
A
CYS
1.00
0.64
0.40
10
40
A
PHE
0.98
1.00
0.64
10
42
A
PRO
0.90
0.47
0.72
10
43
A
ARG
0.93
0.51
0.67
10
44
A
GLY
0.64
0.41
0.82
10
45
A
ASP
0.91
0.32
0.87
10
46
A
MET
0.62
0.66
0.78
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.54
10
50
A
TYR
0.46
0.80
0.49
10
51
A
CYS
1.00
0.64
0.43
10
52
A
CYS
1.00
0.64
0.45
10
57
A
CYS
0.99
0.64
0.60
10
58
A
ASN
0.96
0.39
0.63
10
59
A
LEU
0.00
0.70
0.50
10
6
A
HIS
0.73
0.60
0.51
10
7
A
LEU
0.83
0.70
0.52
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.76
10
18
A
GLN
0.48
0.43
0.74
10
19
A
GLU
0.71
0.33
0.61
10
20
A
ASP
0.66
0.32
0.62
10
26
A
ILE
0.57
0.64
0.46
10
27
A
TRP
1.00
0.99
0.54
10
28
A
THR
0.64
0.33
0.55
10
29
A
PHE
0.80
1.00
0.75
10
30
A
ASP
0.93
0.32
0.72
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.57
10
33
A
ILE
0.71
0.64
0.39
10
39
A
CYS
1.00
0.64
0.39
10
40
A
PHE
0.98
1.00
0.62
10
41
A
THR
0.42
0.33
0.59
10
42
A
PRO
0.90
0.47
0.76
10
43
A
ARG
0.93
0.51
0.81
10
44
A
GLY
0.64
0.41
0.78
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.70
10
47
A
PRO
0.50
0.47
0.72
10
48
A
GLY
0.11
0.41
0.53
10
50
A
TYR
0.46
0.80
0.44
10
51
A
CYS
1.00
0.64
0.35
10
52
A
CYS
1.00
0.64
0.45
10
53
A
GLU
0.40
0.33
0.63
10
59
A
LEU
0.00
0.70
0.45
10
1
A
ARG
0.23
0.51
0.65
10
2
A
ILE
0.61
0.64
0.61
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.51
10
8
A
GLY
0.90
0.41
0.65
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.77
10
11
A
PRO
0.77
0.47
0.71
10
12
A
PRO
0.71
0.47
0.73
10
17
A
CYS
0.96
0.64
0.56
10
18
A
GLN
0.48
0.43
0.77
10
19
A
GLU
0.71
0.33
0.59
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.49
10
27
A
TRP
1.00
0.99
0.58
10
28
A
THR
0.64
0.33
0.58
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.73
10
31
A
ASN
0.73
0.39
0.76
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.38
10
39
A
CYS
1.00
0.64
0.44
10
40
A
PHE
0.98
1.00
0.65
10
41
A
THR
0.42
0.33
0.63
10
42
A
PRO
0.90
0.47
0.75
10
43
A
ARG
0.93
0.51
0.77
10
44
A
GLY
0.64
0.41
0.83
10
45
A
ASP
0.91
0.32
0.85
10
46
A
MET
0.62
0.66
0.71
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.56
10
50
A
TYR
0.46
0.80
0.51
10
51
A
CYS
1.00
0.64
0.48
10
52
A
CYS
1.00
0.64
0.46
10
2
A
ILE
0.61
0.64
0.59
10
6
A
HIS
0.73
0.60
0.52
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.64
10
9
A
THR
0.84
0.33
0.79
10
10
A
LYS
0.71
0.25
0.79
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.76
10
17
A
CYS
0.96
0.64
0.58
10
18
A
GLN
0.48
0.43
0.77
10
19
A
GLU
0.71
0.33
0.64
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.44
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.70
10
31
A
ASN
0.73
0.39
0.71
10
32
A
ILE
0.42
0.64
0.54
10
33
A
ILE
0.71
0.64
0.32
10
39
A
CYS
1.00
0.64
0.45
10
40
A
PHE
0.98
1.00
0.67
10
41
A
THR
0.42
0.33
0.61
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.74
10
44
A
GLY
0.64
0.41
0.82
10
45
A
ASP
0.91
0.32
0.87
10
46
A
MET
0.62
0.66
0.78
10
47
A
PRO
0.50
0.47
0.72
10
48
A
GLY
0.11
0.41
0.55
10
50
A
TYR
0.46
0.80
0.46
10
51
A
CYS
1.00
0.64
0.43
10
52
A
CYS
1.00
0.64
0.44
10
53
A
GLU
0.40
0.33
0.65
10
59
A
LEU
0.00
0.70
0.50
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.53
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.77
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.72
10
12
A
PRO
0.71
0.47
0.74
10
20
A
ASP
0.66
0.32
0.67
10
26
A
ILE
0.57
0.64
0.48
10
27
A
TRP
1.00
0.99
0.54
10
29
A
PHE
0.80
1.00
0.77
10
30
A
ASP
0.93
0.32
0.71
10
31
A
ASN
0.73
0.39
0.74
10
32
A
ILE
0.42
0.64
0.56
10
33
A
ILE
0.71
0.64
0.42
10
39
A
CYS
1.00
0.64
0.41
10
40
A
PHE
0.98
1.00
0.64
10
41
A
THR
0.42
0.33
0.60
10
42
A
PRO
0.90
0.47
0.74
10
43
A
ARG
0.93
0.51
0.83
10
44
A
GLY
0.64
0.41
0.82
10
45
A
ASP
0.91
0.32
0.84
10
46
A
MET
0.62
0.66
0.67
10
47
A
PRO
0.50
0.47
0.69
10
48
A
GLY
0.11
0.41
0.51
10
50
A
TYR
0.46
0.80
0.50
10
51
A
CYS
1.00
0.64
0.44
10
52
A
CYS
1.00
0.64
0.47
10
57
A
CYS
0.99
0.64
0.54
10
59
A
LEU
0.00
0.70
0.50
10
2
A
ILE
0.61
0.64
0.57
10
4
A
TYR
0.67
0.80
0.37
10
6
A
HIS
0.73
0.60
0.49
10
7
A
LEU
0.83
0.70
0.55
10
8
A
GLY
0.90
0.41
0.63
10
9
A
THR
0.84
0.33
0.78
10
10
A
LYS
0.71
0.25
0.78
10
11
A
PRO
0.77
0.47
0.78
10
12
A
PRO
0.71
0.47
0.69
10
13
A
THR
1.00
0.33
0.61
10
17
A
CYS
0.96
0.64
0.57
10
18
A
GLN
0.48
0.43
0.75
10
19
A
GLU
0.71
0.33
0.58
10
20
A
ASP
0.66
0.32
0.66
10
26
A
ILE
0.57
0.64
0.42
10
27
A
TRP
1.00
0.99
0.53
10
29
A
PHE
0.80
1.00
0.76
10
30
A
ASP
0.93
0.32
0.68
10
31
A
ASN
0.73
0.39
0.73
10
32
A
ILE
0.42
0.64
0.52
10
39
A
CYS
1.00
0.64
0.42
10
40
A
PHE
0.98
1.00
0.66
10
41
A
THR
0.42
0.33
0.61
10
42
A
PRO
0.90
0.47
0.77
10
43
A
ARG
0.93
0.51
0.64
10
44
A
GLY
0.64
0.41
0.80
10
45
A
ASP
0.91
0.32
0.78
10
46
A
MET
0.62
0.66
0.77
10
47
A
PRO
0.50
0.47
0.73
10
48
A
GLY
0.11
0.41
0.52
10
50
A
TYR
0.46
0.80
0.43
10
51
A
CYS
1.00
0.64
0.40
10
52
A
CYS
1.00
0.64
0.44
10
53
A
GLU
0.40
0.33
0.68
10