Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DV5 chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
5
A
ALA
0.28
0.38
0.71
2
6
A
ILE
0.46
0.64
0.57
10
8
A
ASN
0.40
0.39
0.62
4
11
A
LEU
0.61
0.70
0.37
8
13
A
ILE
0.66
0.64
0.38
9
16
A
ASP
0.51
0.32
0.57
1
17
A
LEU
0.58
0.70
0.39
10
18
A
THR
0.63
0.33
0.47
1
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
10
21
A
ASP
0.53
0.32
0.74
1
25
A
LYS
0.52
0.25
0.75
7
26
A
ASN
0.54
0.39
0.67
10
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.61
10
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.53
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.40
10
38
A
ASP
0.94
0.32
0.66
10
39
A
SER
1.00
0.36
0.61
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.46
10
42
A
THR
0.57
0.33
0.32
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.58
10
46
A
LEU
0.73
0.70
0.42
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.54
6
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.50
9
54
A
GLY
0.59
0.41
0.69
9
55
A
VAL
0.65
0.56
0.51
9
56
A
ASP
0.33
0.32
0.71
9
57
A
ALA
0.66
0.38
0.52
10
58
A
PRO
0.72
0.47
0.65
10
59
A
VAL
0.73
0.56
0.64
10
60
A
SER
0.66
0.36
0.79
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.65
10
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.47
1
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.32
10
79
A
GLN
0.47
0.43
0.68
10
80
A
ALA
0.58
0.38
0.63
7
81
A
GLN
0.32
0.43
0.68
8
6
A
ILE
0.46
0.64
0.58
7
11
A
LEU
0.61
0.70
0.37
9
13
A
ILE
0.66
0.64
0.36
10
17
A
LEU
0.58
0.70
0.35
10
18
A
THR
0.63
0.33
0.47
8
19
A
GLY
0.60
0.41
0.67
10
20
A
SER
0.46
0.36
0.69
5
25
A
LYS
0.52
0.25
0.75
7
26
A
ASN
0.54
0.39
0.66
10
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
2
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.53
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.69
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.58
10
44
A
GLN
0.74
0.43
0.58
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.51
10
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.50
10
54
A
GLY
0.59
0.41
0.67
10
56
A
ASP
0.33
0.32
0.69
5
57
A
ALA
0.66
0.38
0.55
10
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.57
10
63
A
ASP
0.49
0.32
0.60
2
64
A
ARG
0.79
0.51
0.64
10
66
A
GLU
0.56
0.33
0.44
3
68
A
ASP
0.56
0.32
0.39
6
74
A
ILE
0.57
0.64
0.32
2
79
A
GLN
0.47
0.43
0.69
1
81
A
GLN
0.32
0.43
0.70
1
6
A
ILE
0.46
0.64
0.57
2
11
A
LEU
0.61
0.70
0.42
5
13
A
ILE
0.66
0.64
0.39
9
17
A
LEU
0.58
0.70
0.40
10
18
A
THR
0.63
0.33
0.49
8
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
2
27
A
LEU
0.51
0.70
0.60
10
28
A
ASP
0.76
0.32
0.63
5
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.60
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.55
10
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.68
6
57
A
ALA
0.66
0.38
0.59
10
58
A
PRO
0.72
0.47
0.68
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
63
A
ASP
0.49
0.32
0.61
5
64
A
ARG
0.79
0.51
0.64
10
65
A
LYS
0.44
0.25
0.66
2
66
A
GLU
0.56
0.33
0.42
6
68
A
ASP
0.56
0.32
0.40
10
76
A
LYS
0.62
0.25
0.46
2
79
A
GLN
0.47
0.43
0.68
2
81
A
GLN
0.32
0.43
0.70
1
6
A
ILE
0.46
0.64
0.57
10
8
A
ASN
0.40
0.39
0.63
2
11
A
LEU
0.61
0.70
0.39
10
13
A
ILE
0.66
0.64
0.38
9
17
A
LEU
0.58
0.70
0.38
10
18
A
THR
0.63
0.33
0.48
4
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
9
21
A
ASP
0.53
0.32
0.72
2
25
A
LYS
0.52
0.25
0.75
7
26
A
ASN
0.54
0.39
0.67
10
27
A
LEU
0.51
0.70
0.61
10
28
A
ASP
0.76
0.32
0.63
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.57
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.45
10
38
A
ASP
0.94
0.32
0.70
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.50
10
42
A
THR
0.57
0.33
0.36
10
43
A
VAL
0.80
0.56
0.58
10
44
A
GLN
0.74
0.43
0.58
10
47
A
LEU
0.59
0.70
0.63
10
48
A
GLU
0.54
0.33
0.50
8
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.67
10
56
A
ASP
0.33
0.32
0.71
2
57
A
ALA
0.66
0.38
0.56
10
58
A
PRO
0.72
0.47
0.68
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
64
A
ARG
0.79
0.51
0.63
10
66
A
GLU
0.56
0.33
0.43
3
68
A
ASP
0.56
0.32
0.39
4
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.48
9
72
A
LYS
0.66
0.25
0.50
3
74
A
ILE
0.57
0.64
0.34
10
79
A
GLN
0.47
0.43
0.69
10
6
A
ILE
0.46
0.64
0.56
1
11
A
LEU
0.61
0.70
0.41
4
13
A
ILE
0.66
0.64
0.34
7
17
A
LEU
0.58
0.70
0.36
10
18
A
THR
0.63
0.33
0.47
4
19
A
GLY
0.60
0.41
0.67
8
20
A
SER
0.46
0.36
0.68
1
26
A
ASN
0.54
0.39
0.66
5
27
A
LEU
0.51
0.70
0.56
10
29
A
LEU
0.43
0.70
0.58
10
30
A
ASN
0.58
0.39
0.59
9
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.58
10
44
A
GLN
0.74
0.43
0.58
10
46
A
LEU
0.73
0.70
0.42
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.54
7
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.50
10
54
A
GLY
0.59
0.41
0.68
9
55
A
VAL
0.65
0.56
0.51
10
57
A
ALA
0.66
0.38
0.50
10
58
A
PRO
0.72
0.47
0.68
10
59
A
VAL
0.73
0.56
0.62
10
60
A
SER
0.66
0.36
0.78
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.45
1
68
A
ASP
0.56
0.32
0.39
1
79
A
GLN
0.47
0.43
0.67
1
81
A
GLN
0.32
0.43
0.70
10
6
A
ILE
0.46
0.64
0.58
10
11
A
LEU
0.61
0.70
0.42
7
13
A
ILE
0.66
0.64
0.33
7
17
A
LEU
0.58
0.70
0.34
10
18
A
THR
0.63
0.33
0.49
3
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.71
2
21
A
ASP
0.53
0.32
0.75
1
25
A
LYS
0.52
0.25
0.75
1
26
A
ASN
0.54
0.39
0.65
1
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.58
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.70
10
36
A
LEU
0.56
0.70
0.61
10
37
A
LEU
0.66
0.70
0.44
10
38
A
ASP
0.94
0.32
0.69
10
39
A
SER
1.00
0.36
0.63
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.59
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.52
7
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.68
9
57
A
ALA
0.66
0.38
0.58
10
58
A
PRO
0.72
0.47
0.68
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.56
10
63
A
ASP
0.49
0.32
0.59
1
64
A
ARG
0.79
0.51
0.65
10
68
A
ASP
0.56
0.32
0.41
8
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.46
10
72
A
LYS
0.66
0.25
0.51
2
74
A
ILE
0.57
0.64
0.33
10
79
A
GLN
0.47
0.43
0.68
10
6
A
ILE
0.46
0.64
0.58
4
11
A
LEU
0.61
0.70
0.39
5
13
A
ILE
0.66
0.64
0.37
7
17
A
LEU
0.58
0.70
0.39
10
18
A
THR
0.63
0.33
0.49
6
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.71
8
27
A
LEU
0.51
0.70
0.60
10
28
A
ASP
0.76
0.32
0.63
3
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.55
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.62
10
37
A
LEU
0.66
0.70
0.38
10
38
A
ASP
0.94
0.32
0.62
10
39
A
SER
1.00
0.36
0.70
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.57
10
44
A
GLN
0.74
0.43
0.59
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.50
9
50
A
GLN
0.82
0.43
0.64
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.68
10
54
A
GLY
0.59
0.41
0.68
9
56
A
ASP
0.33
0.32
0.72
2
57
A
ALA
0.66
0.38
0.57
10
58
A
PRO
0.72
0.47
0.69
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
63
A
ASP
0.49
0.32
0.60
4
64
A
ARG
0.79
0.51
0.60
10
66
A
GLU
0.56
0.33
0.44
2
68
A
ASP
0.56
0.32
0.38
9
74
A
ILE
0.57
0.64
0.33
1
76
A
LYS
0.62
0.25
0.47
1
79
A
GLN
0.47
0.43
0.67
2
81
A
GLN
0.32
0.43
0.71
8
6
A
ILE
0.46
0.64
0.56
7
11
A
LEU
0.61
0.70
0.39
6
13
A
ILE
0.66
0.64
0.38
6
17
A
LEU
0.58
0.70
0.41
10
18
A
THR
0.63
0.33
0.48
3
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
2
25
A
LYS
0.52
0.25
0.74
1
26
A
ASN
0.54
0.39
0.65
2
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.53
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.69
8
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.59
10
46
A
LEU
0.73
0.70
0.39
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.51
6
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.67
5
57
A
ALA
0.66
0.38
0.54
10
58
A
PRO
0.72
0.47
0.65
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
64
A
ARG
0.79
0.51
0.63
10
68
A
ASP
0.56
0.32
0.38
2
69
A
THR
0.90
0.33
0.35
10
71
A
ASN
0.59
0.39
0.47
6
72
A
LYS
0.66
0.25
0.50
2
74
A
ILE
0.57
0.64
0.31
10
79
A
GLN
0.47
0.43
0.68
10
6
A
ILE
0.46
0.64
0.58
3
11
A
LEU
0.61
0.70
0.43
4
13
A
ILE
0.66
0.64
0.38
7
17
A
LEU
0.58
0.70
0.36
10
18
A
THR
0.63
0.33
0.49
8
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.71
1
27
A
LEU
0.51
0.70
0.59
10
28
A
ASP
0.76
0.32
0.62
3
29
A
LEU
0.43
0.70
0.61
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.62
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.48
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.59
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.54
10
50
A
GLN
0.82
0.43
0.66
9
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.68
10
54
A
GLY
0.59
0.41
0.69
5
56
A
ASP
0.33
0.32
0.72
3
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.79
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.55
10
63
A
ASP
0.49
0.32
0.60
9
64
A
ARG
0.79
0.51
0.60
10
65
A
LYS
0.44
0.25
0.67
3
66
A
GLU
0.56
0.33
0.44
9
68
A
ASP
0.56
0.32
0.41
10
74
A
ILE
0.57
0.64
0.34
2
76
A
LYS
0.62
0.25
0.45
2
79
A
GLN
0.47
0.43
0.68
3
81
A
GLN
0.32
0.43
0.70
2
6
A
ILE
0.46
0.64
0.57
10
8
A
ASN
0.40
0.39
0.66
4
11
A
LEU
0.61
0.70
0.43
10
13
A
ILE
0.66
0.64
0.40
8
17
A
LEU
0.58
0.70
0.38
10
18
A
THR
0.63
0.33
0.49
4
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.72
10
21
A
ASP
0.53
0.32
0.73
1
25
A
LYS
0.52
0.25
0.75
7
26
A
ASN
0.54
0.39
0.64
7
27
A
LEU
0.51
0.70
0.59
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.56
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.42
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.48
10
43
A
VAL
0.80
0.56
0.56
10
44
A
GLN
0.74
0.43
0.57
10
47
A
LEU
0.59
0.70
0.63
10
48
A
GLU
0.54
0.33
0.53
9
50
A
GLN
0.82
0.43
0.64
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.66
10
54
A
GLY
0.59
0.41
0.66
9
57
A
ALA
0.66
0.38
0.46
9
58
A
PRO
0.72
0.47
0.62
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.57
10
63
A
ASP
0.49
0.32
0.60
2
64
A
ARG
0.79
0.51
0.61
10
66
A
GLU
0.56
0.33
0.44
6
68
A
ASP
0.56
0.32
0.40
7
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.47
10
72
A
LYS
0.66
0.25
0.51
2
74
A
ILE
0.57
0.64
0.31
10
79
A
GLN
0.47
0.43
0.68
10
6
A
ILE
0.46
0.64
0.57
9
11
A
LEU
0.61
0.70
0.36
6
13
A
ILE
0.66
0.64
0.38
7
17
A
LEU
0.58
0.70
0.41
10
18
A
THR
0.63
0.33
0.48
4
19
A
GLY
0.60
0.41
0.67
10
22
A
ASP
0.49
0.32
0.72
1
25
A
LYS
0.52
0.25
0.74
2
26
A
ASN
0.54
0.39
0.63
2
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.58
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.49
10
33
A
GLU
0.59
0.33
0.72
10
34
A
THR
0.60
0.33
0.71
10
35
A
GLY
0.88
0.41
0.73
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.70
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.59
10
46
A
LEU
0.73
0.70
0.39
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.52
7
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.68
6
55
A
VAL
0.65
0.56
0.51
10
57
A
ALA
0.66
0.38
0.51
10
58
A
PRO
0.72
0.47
0.63
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
64
A
ARG
0.79
0.51
0.58
10
66
A
GLU
0.56
0.33
0.45
1
69
A
THR
0.90
0.33
0.35
10
71
A
ASN
0.59
0.39
0.46
7
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.31
10
79
A
GLN
0.47
0.43
0.69
10
81
A
GLN
0.32
0.43
0.71
10
5
A
ALA
0.28
0.38
0.70
1
6
A
ILE
0.46
0.64
0.56
7
11
A
LEU
0.61
0.70
0.34
8
13
A
ILE
0.66
0.64
0.38
10
17
A
LEU
0.58
0.70
0.43
10
18
A
THR
0.63
0.33
0.49
3
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.68
4
25
A
LYS
0.52
0.25
0.75
4
26
A
ASN
0.54
0.39
0.67
9
27
A
LEU
0.51
0.70
0.59
10
29
A
LEU
0.43
0.70
0.56
10
30
A
ASN
0.58
0.39
0.58
8
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.54
10
46
A
LEU
0.73
0.70
0.41
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.51
8
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
10
55
A
VAL
0.65
0.56
0.51
10
57
A
ALA
0.66
0.38
0.55
10
58
A
PRO
0.72
0.47
0.71
10
59
A
VAL
0.73
0.56
0.64
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.64
10
66
A
GLU
0.56
0.33
0.43
2
80
A
ALA
0.58
0.38
0.65
8
81
A
GLN
0.32
0.43
0.71
9
6
A
ILE
0.46
0.64
0.57
10
11
A
LEU
0.61
0.70
0.37
10
13
A
ILE
0.66
0.64
0.39
10
16
A
ASP
0.51
0.32
0.59
1
17
A
LEU
0.58
0.70
0.44
10
18
A
THR
0.63
0.33
0.51
3
19
A
GLY
0.60
0.41
0.70
10
20
A
SER
0.46
0.36
0.71
10
25
A
LYS
0.52
0.25
0.75
10
26
A
ASN
0.54
0.39
0.67
10
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.56
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.42
10
38
A
ASP
0.94
0.32
0.66
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.50
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.55
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.50
8
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.67
10
56
A
ASP
0.33
0.32
0.69
8
57
A
ALA
0.66
0.38
0.57
10
58
A
PRO
0.72
0.47
0.67
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
63
A
ASP
0.49
0.32
0.64
1
64
A
ARG
0.79
0.51
0.63
10
69
A
THR
0.90
0.33
0.35
10
71
A
ASN
0.59
0.39
0.47
10
72
A
LYS
0.66
0.25
0.50
1
74
A
ILE
0.57
0.64
0.31
10
79
A
GLN
0.47
0.43
0.67
10
2
A
ALA
0.00
0.38
0.83
1
3
A
ASP
0.06
0.32
0.79
1
4
A
GLU
0.03
0.33
0.76
1
5
A
ALA
0.28
0.38
0.72
6
6
A
ILE
0.46
0.64
0.58
10
11
A
LEU
0.61
0.70
0.38
7
13
A
ILE
0.66
0.64
0.36
8
17
A
LEU
0.58
0.70
0.41
10
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.71
5
26
A
ASN
0.54
0.39
0.67
4
27
A
LEU
0.51
0.70
0.61
10
28
A
ASP
0.76
0.32
0.63
10
29
A
LEU
0.43
0.70
0.58
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.55
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.66
9
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.63
10
37
A
LEU
0.66
0.70
0.39
10
38
A
ASP
0.94
0.32
0.63
10
39
A
SER
1.00
0.36
0.71
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.56
10
44
A
GLN
0.74
0.43
0.59
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.52
4
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
10
57
A
ALA
0.66
0.38
0.57
10
58
A
PRO
0.72
0.47
0.69
10
59
A
VAL
0.73
0.56
0.66
10
60
A
SER
0.66
0.36
0.79
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.54
10
64
A
ARG
0.79
0.51
0.61
10
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.49
5
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.35
10
79
A
GLN
0.47
0.43
0.67
5
81
A
GLN
0.32
0.43
0.68
6
5
A
ALA
0.28
0.38
0.70
1
6
A
ILE
0.46
0.64
0.56
10
8
A
ASN
0.40
0.39
0.60
5
11
A
LEU
0.61
0.70
0.34
10
13
A
ILE
0.66
0.64
0.39
10
16
A
ASP
0.51
0.32
0.59
1
17
A
LEU
0.58
0.70
0.42
10
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.71
10
25
A
LYS
0.52
0.25
0.75
10
26
A
ASN
0.54
0.39
0.65
9
27
A
LEU
0.51
0.70
0.56
10
28
A
ASP
0.76
0.32
0.60
10
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.66
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.42
10
38
A
ASP
0.94
0.32
0.66
10
39
A
SER
1.00
0.36
0.60
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.47
10
42
A
THR
0.57
0.33
0.34
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.57
10
46
A
LEU
0.73
0.70
0.41
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.53
9
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.50
10
54
A
GLY
0.59
0.41
0.68
10
55
A
VAL
0.65
0.56
0.52
10
56
A
ASP
0.33
0.32
0.71
10
57
A
ALA
0.66
0.38
0.53
10
58
A
PRO
0.72
0.47
0.65
10
59
A
VAL
0.73
0.56
0.63
10
60
A
SER
0.66
0.36
0.79
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.65
10
69
A
THR
0.90
0.33
0.37
10
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.31
10
79
A
GLN
0.47
0.43
0.69
10
80
A
ALA
0.58
0.38
0.64
8
81
A
GLN
0.32
0.43
0.70
8
6
A
ILE
0.46
0.64
0.56
2
11
A
LEU
0.61
0.70
0.39
2
13
A
ILE
0.66
0.64
0.35
8
17
A
LEU
0.58
0.70
0.35
10
18
A
THR
0.63
0.33
0.48
3
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
3
27
A
LEU
0.51
0.70
0.58
10
29
A
LEU
0.43
0.70
0.54
10
30
A
ASN
0.58
0.39
0.61
10
32
A
PHE
0.75
1.00
0.56
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.68
9
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.41
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.48
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.58
10
46
A
LEU
0.73
0.70
0.42
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.53
8
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
9
55
A
VAL
0.65
0.56
0.52
10
56
A
ASP
0.33
0.32
0.71
1
57
A
ALA
0.66
0.38
0.52
10
58
A
PRO
0.72
0.47
0.69
10
59
A
VAL
0.73
0.56
0.65
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.44
1
68
A
ASP
0.56
0.32
0.40
1
79
A
GLN
0.47
0.43
0.67
1
80
A
ALA
0.58
0.38
0.63
3
81
A
GLN
0.32
0.43
0.69
10
6
A
ILE
0.46
0.64
0.58
10
11
A
LEU
0.61
0.70
0.38
10
13
A
ILE
0.66
0.64
0.42
10
16
A
ASP
0.51
0.32
0.62
4
17
A
LEU
0.58
0.70
0.45
10
18
A
THR
0.63
0.33
0.50
3
19
A
GLY
0.60
0.41
0.70
10
20
A
SER
0.46
0.36
0.70
10
25
A
LYS
0.52
0.25
0.75
10
26
A
ASN
0.54
0.39
0.65
10
27
A
LEU
0.51
0.70
0.60
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.66
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.52
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.56
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.51
6
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.67
10
56
A
ASP
0.33
0.32
0.69
1
57
A
ALA
0.66
0.38
0.59
10
58
A
PRO
0.72
0.47
0.69
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.43
1
68
A
ASP
0.56
0.32
0.39
1
69
A
THR
0.90
0.33
0.35
10
71
A
ASN
0.59
0.39
0.47
8
72
A
LYS
0.66
0.25
0.50
1
74
A
ILE
0.57
0.64
0.33
10
79
A
GLN
0.47
0.43
0.69
10
6
A
ILE
0.46
0.64
0.57
10
13
A
ILE
0.66
0.64
0.38
10
17
A
LEU
0.58
0.70
0.44
10
18
A
THR
0.63
0.33
0.48
2
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.69
10
21
A
ASP
0.53
0.32
0.74
1
25
A
LYS
0.52
0.25
0.75
10
26
A
ASN
0.54
0.39
0.65
10
27
A
LEU
0.51
0.70
0.59
10
28
A
ASP
0.76
0.32
0.61
10
29
A
LEU
0.43
0.70
0.56
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.52
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.63
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.54
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.49
7
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.50
10
54
A
GLY
0.59
0.41
0.69
10
55
A
VAL
0.65
0.56
0.51
6
56
A
ASP
0.33
0.32
0.70
4
57
A
ALA
0.66
0.38
0.51
10
58
A
PRO
0.72
0.47
0.64
10
59
A
VAL
0.73
0.56
0.66
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.54
10
64
A
ARG
0.79
0.51
0.61
10
69
A
THR
0.90
0.33
0.35
10
71
A
ASN
0.59
0.39
0.46
6
74
A
ILE
0.57
0.64
0.30
10
79
A
GLN
0.47
0.43
0.66
10
80
A
ALA
0.58
0.38
0.65
6
81
A
GLN
0.32
0.43
0.69
6
6
A
ILE
0.46
0.64
0.58
5
11
A
LEU
0.61
0.70
0.36
6
13
A
ILE
0.66
0.64
0.41
10
17
A
LEU
0.58
0.70
0.43
10
18
A
THR
0.63
0.33
0.47
3
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.70
10
21
A
ASP
0.53
0.32
0.76
3
25
A
LYS
0.52
0.25
0.74
3
26
A
ASN
0.54
0.39
0.64
9
27
A
LEU
0.51
0.70
0.59
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.58
10
30
A
ASN
0.58
0.39
0.61
10
32
A
PHE
0.75
1.00
0.57
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.65
10
35
A
GLY
0.88
0.41
0.69
10
36
A
LEU
0.56
0.70
0.57
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.50
10
42
A
THR
0.57
0.33
0.36
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.58
10
46
A
LEU
0.73
0.70
0.39
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.53
5
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.69
10
54
A
GLY
0.59
0.41
0.69
9
55
A
VAL
0.65
0.56
0.50
9
57
A
ALA
0.66
0.38
0.53
10
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
64
A
ARG
0.79
0.51
0.63
10
66
A
GLU
0.56
0.33
0.45
2
68
A
ASP
0.56
0.32
0.42
1
69
A
THR
0.90
0.33
0.37
10
71
A
ASN
0.59
0.39
0.45
3
72
A
LYS
0.66
0.25
0.51
1
79
A
GLN
0.47
0.43
0.67
2
80
A
ALA
0.58
0.38
0.65
2
81
A
GLN
0.32
0.43
0.70
8
6
A
ILE
0.46
0.64
0.57
5
11
A
LEU
0.61
0.70
0.38
6
13
A
ILE
0.66
0.64
0.39
10
17
A
LEU
0.58
0.70
0.47
10
18
A
THR
0.63
0.33
0.50
4
19
A
GLY
0.60
0.41
0.70
7
20
A
SER
0.46
0.36
0.70
3
26
A
ASN
0.54
0.39
0.66
1
27
A
LEU
0.51
0.70
0.58
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
9
32
A
PHE
0.75
1.00
0.55
10
33
A
GLU
0.59
0.33
0.75
9
34
A
THR
0.60
0.33
0.68
9
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.58
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.61
10
44
A
GLN
0.74
0.43
0.56
10
46
A
LEU
0.73
0.70
0.40
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.51
6
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.71
9
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
8
55
A
VAL
0.65
0.56
0.51
10
57
A
ALA
0.66
0.38
0.54
10
58
A
PRO
0.72
0.47
0.65
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.78
10
62
A
PHE
0.76
1.00
0.56
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.44
1
68
A
ASP
0.56
0.32
0.39
1
81
A
GLN
0.32
0.43
0.70
7
5
A
ALA
0.28
0.38
0.72
1
6
A
ILE
0.46
0.64
0.57
3
11
A
LEU
0.61
0.70
0.41
4
13
A
ILE
0.66
0.64
0.36
8
17
A
LEU
0.58
0.70
0.37
10
18
A
THR
0.63
0.33
0.49
9
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.71
2
21
A
ASP
0.53
0.32
0.76
1
25
A
LYS
0.52
0.25
0.76
1
26
A
ASN
0.54
0.39
0.68
9
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.61
4
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.58
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.60
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.64
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.61
10
44
A
GLN
0.74
0.43
0.60
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.53
9
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
10
56
A
ASP
0.33
0.32
0.71
4
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.81
10
62
A
PHE
0.76
1.00
0.59
10
63
A
ASP
0.49
0.32
0.64
4
64
A
ARG
0.79
0.51
0.50
10
66
A
GLU
0.56
0.33
0.43
3
68
A
ASP
0.56
0.32
0.41
4
79
A
GLN
0.47
0.43
0.69
3
5
A
ALA
0.28
0.38
0.72
2
6
A
ILE
0.46
0.64
0.56
10
11
A
LEU
0.61
0.70
0.38
8
13
A
ILE
0.66
0.64
0.36
8
17
A
LEU
0.58
0.70
0.40
10
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.71
8
25
A
LYS
0.52
0.25
0.75
2
26
A
ASN
0.54
0.39
0.65
5
27
A
LEU
0.51
0.70
0.57
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
7
32
A
PHE
0.75
1.00
0.53
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.59
10
38
A
ASP
0.94
0.32
0.67
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.71
10
41
A
GLY
0.52
0.41
0.47
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.59
10
46
A
LEU
0.73
0.70
0.42
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.53
4
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.67
10
55
A
VAL
0.65
0.56
0.50
9
56
A
ASP
0.33
0.32
0.71
7
57
A
ALA
0.66
0.38
0.53
10
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.66
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.57
10
64
A
ARG
0.79
0.51
0.65
10
69
A
THR
0.90
0.33
0.36
10
71
A
ASN
0.59
0.39
0.45
8
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.33
10
79
A
GLN
0.47
0.43
0.69
10
80
A
ALA
0.58
0.38
0.64
4
81
A
GLN
0.32
0.43
0.70
9
6
A
ILE
0.46
0.64
0.57
10
8
A
ASN
0.40
0.39
0.64
1
11
A
LEU
0.61
0.70
0.41
10
13
A
ILE
0.66
0.64
0.37
10
17
A
LEU
0.58
0.70
0.36
10
18
A
THR
0.63
0.33
0.50
1
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.72
1
21
A
ASP
0.53
0.32
0.72
1
25
A
LYS
0.52
0.25
0.74
8
26
A
ASN
0.54
0.39
0.67
10
27
A
LEU
0.51
0.70
0.58
10
28
A
ASP
0.76
0.32
0.62
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.61
10
32
A
PHE
0.75
1.00
0.56
10
33
A
GLU
0.59
0.33
0.76
10
34
A
THR
0.60
0.33
0.69
10
35
A
GLY
0.88
0.41
0.70
10
36
A
LEU
0.56
0.70
0.57
10
37
A
LEU
0.66
0.70
0.40
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.49
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.60
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.52
8
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
9
56
A
ASP
0.33
0.32
0.72
10
57
A
ALA
0.66
0.38
0.54
10
58
A
PRO
0.72
0.47
0.65
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.57
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.44
2
68
A
ASP
0.56
0.32
0.41
1
69
A
THR
0.90
0.33
0.37
10
71
A
ASN
0.59
0.39
0.47
9
72
A
LYS
0.66
0.25
0.51
1
74
A
ILE
0.57
0.64
0.32
10
79
A
GLN
0.47
0.43
0.68
10
80
A
ALA
0.58
0.38
0.62
4
6
A
ILE
0.46
0.64
0.56
2
11
A
LEU
0.61
0.70
0.39
5
13
A
ILE
0.66
0.64
0.39
10
17
A
LEU
0.58
0.70
0.42
10
18
A
THR
0.63
0.33
0.49
5
19
A
GLY
0.60
0.41
0.69
9
20
A
SER
0.46
0.36
0.71
3
26
A
ASN
0.54
0.39
0.65
1
27
A
LEU
0.51
0.70
0.58
10
29
A
LEU
0.43
0.70
0.58
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.54
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.70
10
36
A
LEU
0.56
0.70
0.55
10
37
A
LEU
0.66
0.70
0.42
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.63
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.50
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.55
10
46
A
LEU
0.73
0.70
0.42
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.50
8
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.70
8
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.68
6
57
A
ALA
0.66
0.38
0.54
10
58
A
PRO
0.72
0.47
0.68
10
59
A
VAL
0.73
0.56
0.68
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.57
10
63
A
ASP
0.49
0.32
0.64
3
64
A
ARG
0.79
0.51
0.62
10
66
A
GLU
0.56
0.33
0.44
3
68
A
ASP
0.56
0.32
0.40
3
6
A
ILE
0.46
0.64
0.56
1
11
A
LEU
0.61
0.70
0.39
1
13
A
ILE
0.66
0.64
0.37
8
17
A
LEU
0.58
0.70
0.35
10
18
A
THR
0.63
0.33
0.46
6
19
A
GLY
0.60
0.41
0.67
10
20
A
SER
0.46
0.36
0.70
6
26
A
ASN
0.54
0.39
0.66
4
27
A
LEU
0.51
0.70
0.58
4
28
A
ASP
0.76
0.32
0.62
2
29
A
LEU
0.43
0.70
0.57
10
30
A
ASN
0.58
0.39
0.58
10
32
A
PHE
0.75
1.00
0.50
10
33
A
GLU
0.59
0.33
0.72
10
34
A
THR
0.60
0.33
0.67
10
35
A
GLY
0.88
0.41
0.69
10
36
A
LEU
0.56
0.70
0.57
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.67
10
40
A
MET
0.78
0.66
0.69
10
41
A
GLY
0.52
0.41
0.44
10
43
A
VAL
0.80
0.56
0.58
10
44
A
GLN
0.74
0.43
0.56
10
46
A
LEU
0.73
0.70
0.38
10
47
A
LEU
0.59
0.70
0.63
10
48
A
GLU
0.54
0.33
0.49
9
50
A
GLN
0.82
0.43
0.64
10
51
A
SER
0.41
0.36
0.68
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.68
8
55
A
VAL
0.65
0.56
0.50
10
57
A
ALA
0.66
0.38
0.55
10
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.58
10
63
A
ASP
0.49
0.32
0.62
2
64
A
ARG
0.79
0.51
0.61
10
66
A
GLU
0.56
0.33
0.45
1
68
A
ASP
0.56
0.32
0.41
5
79
A
GLN
0.47
0.43
0.66
1
81
A
GLN
0.32
0.43
0.69
8
6
A
ILE
0.46
0.64
0.57
1
11
A
LEU
0.61
0.70
0.40
9
13
A
ILE
0.66
0.64
0.41
9
17
A
LEU
0.58
0.70
0.38
10
18
A
THR
0.63
0.33
0.51
8
19
A
GLY
0.60
0.41
0.70
6
20
A
SER
0.46
0.36
0.72
2
25
A
LYS
0.52
0.25
0.76
1
27
A
LEU
0.51
0.70
0.58
10
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.60
10
32
A
PHE
0.75
1.00
0.53
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.58
10
37
A
LEU
0.66
0.70
0.44
10
38
A
ASP
0.94
0.32
0.69
10
39
A
SER
1.00
0.36
0.66
10
40
A
MET
0.78
0.66
0.73
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.61
10
44
A
GLN
0.74
0.43
0.55
10
46
A
LEU
0.73
0.70
0.40
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.50
8
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.70
6
52
A
GLN
0.41
0.43
0.63
5
54
A
GLY
0.59
0.41
0.68
2
55
A
VAL
0.65
0.56
0.51
10
57
A
ALA
0.66
0.38
0.51
10
58
A
PRO
0.72
0.47
0.63
10
59
A
VAL
0.73
0.56
0.70
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.58
10
63
A
ASP
0.49
0.32
0.62
1
64
A
ARG
0.79
0.51
0.56
10
66
A
GLU
0.56
0.33
0.45
4
68
A
ASP
0.56
0.32
0.39
3
74
A
ILE
0.57
0.64
0.31
1
79
A
GLN
0.47
0.43
0.67
1
81
A
GLN
0.32
0.43
0.72
6
6
A
ILE
0.46
0.64
0.54
2
8
A
ASN
0.40
0.39
0.62
1
11
A
LEU
0.61
0.70
0.37
4
13
A
ILE
0.66
0.64
0.36
8
17
A
LEU
0.58
0.70
0.40
10
18
A
THR
0.63
0.33
0.47
6
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
8
26
A
ASN
0.54
0.39
0.65
2
27
A
LEU
0.51
0.70
0.56
3
28
A
ASP
0.76
0.32
0.60
2
29
A
LEU
0.43
0.70
0.56
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.52
10
33
A
GLU
0.59
0.33
0.73
10
34
A
THR
0.60
0.33
0.68
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.58
10
37
A
LEU
0.66
0.70
0.43
10
38
A
ASP
0.94
0.32
0.68
10
39
A
SER
1.00
0.36
0.62
10
40
A
MET
0.78
0.66
0.70
10
41
A
GLY
0.52
0.41
0.46
10
42
A
THR
0.57
0.33
0.31
10
43
A
VAL
0.80
0.56
0.58
10
44
A
GLN
0.74
0.43
0.57
10
46
A
LEU
0.73
0.70
0.36
10
47
A
LEU
0.59
0.70
0.64
10
48
A
GLU
0.54
0.33
0.52
7
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.67
10
54
A
GLY
0.59
0.41
0.66
10
56
A
ASP
0.33
0.32
0.68
3
57
A
ALA
0.66
0.38
0.47
10
58
A
PRO
0.72
0.47
0.63
10
59
A
VAL
0.73
0.56
0.67
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
64
A
ARG
0.79
0.51
0.58
10
66
A
GLU
0.56
0.33
0.45
3
68
A
ASP
0.56
0.32
0.39
3
6
A
ILE
0.46
0.64
0.56
5
8
A
ASN
0.40
0.39
0.66
2
11
A
LEU
0.61
0.70
0.43
9
13
A
ILE
0.66
0.64
0.38
10
17
A
LEU
0.58
0.70
0.36
10
18
A
THR
0.63
0.33
0.51
7
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.72
6
25
A
LYS
0.52
0.25
0.75
5
26
A
ASN
0.54
0.39
0.65
5
27
A
LEU
0.51
0.70
0.59
8
28
A
ASP
0.76
0.32
0.62
4
29
A
LEU
0.43
0.70
0.59
10
30
A
ASN
0.58
0.39
0.58
10
32
A
PHE
0.75
1.00
0.49
10
33
A
GLU
0.59
0.33
0.74
10
34
A
THR
0.60
0.33
0.71
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.56
10
37
A
LEU
0.66
0.70
0.45
10
38
A
ASP
0.94
0.32
0.70
10
39
A
SER
1.00
0.36
0.65
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.52
10
43
A
VAL
0.80
0.56
0.61
10
44
A
GLN
0.74
0.43
0.57
10
47
A
LEU
0.59
0.70
0.66
10
48
A
GLU
0.54
0.33
0.51
10
50
A
GLN
0.82
0.43
0.66
10
51
A
SER
0.41
0.36
0.71
10
52
A
GLN
0.41
0.43
0.67
10
53
A
PHE
0.71
1.00
0.50
10
54
A
GLY
0.59
0.41
0.67
10
56
A
ASP
0.33
0.32
0.70
1
58
A
PRO
0.72
0.47
0.67
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.79
10
62
A
PHE
0.76
1.00
0.59
10
63
A
ASP
0.49
0.32
0.59
10
64
A
ARG
0.79
0.51
0.57
10
65
A
LYS
0.44
0.25
0.66
1
66
A
GLU
0.56
0.33
0.45
8
76
A
LYS
0.62
0.25
0.47
1
79
A
GLN
0.47
0.43
0.67
1
81
A
GLN
0.32
0.43
0.69
2
5
A
ALA
0.28
0.38
0.72
2
6
A
ILE
0.46
0.64
0.57
8
11
A
LEU
0.61
0.70
0.37
9
13
A
ILE
0.66
0.64
0.38
10
17
A
LEU
0.58
0.70
0.40
10
18
A
THR
0.63
0.33
0.49
8
19
A
GLY
0.60
0.41
0.68
10
20
A
SER
0.46
0.36
0.70
5
25
A
LYS
0.52
0.25
0.76
1
26
A
ASN
0.54
0.39
0.67
7
27
A
LEU
0.51
0.70
0.61
10
28
A
ASP
0.76
0.32
0.62
1
29
A
LEU
0.43
0.70
0.56
10
30
A
ASN
0.58
0.39
0.59
10
32
A
PHE
0.75
1.00
0.51
10
33
A
GLU
0.59
0.33
0.75
10
34
A
THR
0.60
0.33
0.71
10
35
A
GLY
0.88
0.41
0.72
10
36
A
LEU
0.56
0.70
0.61
10
37
A
LEU
0.66
0.70
0.46
10
38
A
ASP
0.94
0.32
0.69
10
39
A
SER
1.00
0.36
0.63
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.52
10
43
A
VAL
0.80
0.56
0.60
10
44
A
GLN
0.74
0.43
0.55
10
47
A
LEU
0.59
0.70
0.65
10
48
A
GLU
0.54
0.33
0.51
8
50
A
GLN
0.82
0.43
0.67
10
51
A
SER
0.41
0.36
0.70
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.69
10
55
A
VAL
0.65
0.56
0.53
8
57
A
ALA
0.66
0.38
0.54
10
58
A
PRO
0.72
0.47
0.66
10
59
A
VAL
0.73
0.56
0.69
10
60
A
SER
0.66
0.36
0.81
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
64
A
ARG
0.79
0.51
0.59
10
66
A
GLU
0.56
0.33
0.44
1
68
A
ASP
0.56
0.32
0.38
1
74
A
ILE
0.57
0.64
0.34
1
81
A
GLN
0.32
0.43
0.71
8
6
A
ILE
0.46
0.64
0.58
10
8
A
ASN
0.40
0.39
0.65
1
11
A
LEU
0.61
0.70
0.42
10
13
A
ILE
0.66
0.64
0.38
10
17
A
LEU
0.58
0.70
0.38
10
18
A
THR
0.63
0.33
0.50
1
19
A
GLY
0.60
0.41
0.69
10
20
A
SER
0.46
0.36
0.72
10
25
A
LYS
0.52
0.25
0.76
10
26
A
ASN
0.54
0.39
0.64
9
27
A
LEU
0.51
0.70
0.60
10
28
A
ASP
0.76
0.32
0.63
10
29
A
LEU
0.43
0.70
0.61
10
30
A
ASN
0.58
0.39
0.61
10
32
A
PHE
0.75
1.00
0.58
10
33
A
GLU
0.59
0.33
0.76
10
34
A
THR
0.60
0.33
0.70
10
35
A
GLY
0.88
0.41
0.71
10
36
A
LEU
0.56
0.70
0.58
10
37
A
LEU
0.66
0.70
0.44
10
38
A
ASP
0.94
0.32
0.70
10
39
A
SER
1.00
0.36
0.66
10
40
A
MET
0.78
0.66
0.72
10
41
A
GLY
0.52
0.41
0.51
10
43
A
VAL
0.80
0.56
0.59
10
44
A
GLN
0.74
0.43
0.58
10
47
A
LEU
0.59
0.70
0.63
10
48
A
GLU
0.54
0.33
0.52
8
50
A
GLN
0.82
0.43
0.65
10
51
A
SER
0.41
0.36
0.69
10
52
A
GLN
0.41
0.43
0.68
10
53
A
PHE
0.71
1.00
0.51
10
54
A
GLY
0.59
0.41
0.68
10
58
A
PRO
0.72
0.47
0.63
10
59
A
VAL
0.73
0.56
0.70
10
60
A
SER
0.66
0.36
0.80
10
61
A
GLU
0.72
0.33
0.80
10
62
A
PHE
0.76
1.00
0.58
10
64
A
ARG
0.79
0.51
0.65
10
66
A
GLU
0.56
0.33
0.43
1
68
A
ASP
0.56
0.32
0.42
2
69
A
THR
0.90
0.33
0.38
10
71
A
ASN
0.59
0.39
0.48
9
72
A
LYS
0.66
0.25
0.51
2
74
A
ILE
0.57
0.64
0.34
10
79
A
GLN
0.47
0.43
0.69
10