Pre-computed interfaces

How to use JET2 Viewer

References

Contact

JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DVH chain A sc1

 

Download file

 

 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
9
3
A
GLY
0.62
0.41
0.45
9
4
A
ALA
0.41
0.38
0.54
9
5
A
ALA
0.37
0.38
0.61
9
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
8
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.51
8
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.56
6
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.47
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.49
10
37
A
LEU
0.67
0.70
0.11
10
38
A
TYR
0.35
0.80
0.41
10
40
A
LYS
0.69
0.25
0.31
6
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
5
44
A
TYR
0.79
0.80
0.29
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.59
10
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.60
10
62
A
LYS
0.42
0.25
0.60
8
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.38
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
7
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.53
4
71
A
ALA
0.71
0.38
0.42
1
74
A
ASP
0.64
0.32
0.52
4
75
A
TYR
0.87
0.80
0.44
10
76
A
MET
0.63
0.66
0.06
10
77
A
SER
0.59
0.36
0.49
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.66
10
2
A
ASP
0.37
0.32
0.66
10
3
A
GLY
0.62
0.41
0.44
9
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.65
9
25
A
SER
0.40
0.36
0.65
10
27
A
LYS
0.72
0.25
0.53
10
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.59
9
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.45
10
40
A
LYS
0.69
0.25
0.34
8
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
9
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.66
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.50
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.16
10
58
A
THR
0.58
0.33
0.47
3
59
A
ASN
0.61
0.39
0.60
10
60
A
ALA
0.58
0.38
0.34
4
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.59
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
6
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.56
9
71
A
ALA
0.71
0.38
0.43
3
74
A
ASP
0.64
0.32
0.52
8
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.74
10
2
A
ASP
0.37
0.32
0.66
10
3
A
GLY
0.62
0.41
0.51
10
4
A
ALA
0.41
0.38
0.52
10
5
A
ALA
0.37
0.38
0.59
10
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.46
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.60
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
10
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.50
8
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.16
10
30
A
LYS
0.68
0.25
0.56
9
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.46
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.48
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.26
5
43
A
GLY
0.64
0.41
0.46
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.45
9
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.67
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.49
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.68
10
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.14
10
58
A
THR
0.58
0.33
0.43
1
59
A
ASN
0.61
0.39
0.56
10
60
A
ALA
0.58
0.38
0.30
7
62
A
LYS
0.42
0.25
0.58
9
63
A
LYS
0.43
0.25
0.56
9
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.65
10
68
A
GLU
0.71
0.33
0.50
10
71
A
ALA
0.71
0.38
0.40
6
74
A
ASP
0.64
0.32
0.50
5
75
A
TYR
0.87
0.80
0.42
10
77
A
SER
0.59
0.36
0.48
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.47
2
27
A
LYS
0.72
0.25
0.51
9
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.31
9
43
A
GLY
0.64
0.41
0.46
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.67
10
53
A
ARG
0.42
0.51
0.62
10
54
A
LYS
0.52
0.25
0.61
10
55
A
ALA
0.44
0.38
0.62
10
56
A
MET
0.56
0.66
0.52
10
57
A
MET
0.98
0.66
0.18
10
58
A
THR
0.58
0.33
0.47
2
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.34
7
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.52
10
71
A
ALA
0.71
0.38
0.43
4
74
A
ASP
0.64
0.32
0.52
9
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
9
2
A
ASP
0.37
0.32
0.67
9
3
A
GLY
0.62
0.41
0.45
9
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.61
9
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.59
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
9
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.67
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.64
7
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.50
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.59
8
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.32
10
33
A
GLY
0.51
0.41
0.47
10
34
A
ALA
0.57
0.38
0.47
9
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.33
3
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.47
5
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.69
4
53
A
ARG
0.42
0.51
0.58
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
8
64
A
TYR
0.83
0.80
0.39
9
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.62
4
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.50
8
71
A
ALA
0.71
0.38
0.43
1
74
A
ASP
0.64
0.32
0.53
8
75
A
TYR
0.87
0.80
0.47
10
76
A
MET
0.63
0.66
0.08
10
77
A
SER
0.59
0.36
0.51
9
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.80
1
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.58
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.27
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.51
10
14
A
HIS
1.00
0.60
0.28
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.69
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.70
10
27
A
LYS
0.72
0.25
0.52
4
28
A
PRO
0.65
0.47
0.53
9
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.56
8
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.49
9
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.45
10
40
A
LYS
0.69
0.25
0.30
6
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
9
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
9
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.65
10
51
A
GLY
0.64
0.41
0.68
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.45
1
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.34
5
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.58
9
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.57
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.52
10
71
A
ALA
0.71
0.38
0.44
9
74
A
ASP
0.64
0.32
0.55
8
75
A
TYR
0.87
0.80
0.49
10
77
A
SER
0.59
0.36
0.48
8
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.46
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.44
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.61
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.64
10
24
A
GLY
0.52
0.41
0.66
9
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.48
1
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.54
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.31
9
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
8
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.64
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.76
10
53
A
ARG
0.42
0.51
0.65
10
55
A
ALA
0.44
0.38
0.57
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.14
10
58
A
THR
0.58
0.33
0.44
2
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.35
3
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.59
3
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
1
66
A
ASP
0.69
0.32
0.62
9
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.52
10
74
A
ASP
0.64
0.32
0.54
8
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.54
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.45
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.60
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.34
9
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.30
10
45
A
ALA
0.65
0.38
0.49
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.60
10
52
A
GLU
0.60
0.33
0.67
10
53
A
ARG
0.42
0.51
0.63
10
54
A
LYS
0.52
0.25
0.60
6
55
A
ALA
0.44
0.38
0.62
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.18
10
58
A
THR
0.58
0.33
0.47
1
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.34
7
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.53
10
71
A
ALA
0.71
0.38
0.45
2
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.55
10
2
A
ASP
0.37
0.32
0.68
10
3
A
GLY
0.62
0.41
0.54
10
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.49
5
28
A
PRO
0.65
0.47
0.52
9
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.48
9
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.48
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.34
5
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
9
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.46
8
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.65
10
51
A
GLY
0.64
0.41
0.69
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.18
10
58
A
THR
0.58
0.33
0.45
2
59
A
ASN
0.61
0.39
0.60
10
60
A
ALA
0.58
0.38
0.36
5
62
A
LYS
0.42
0.25
0.57
9
63
A
LYS
0.43
0.25
0.55
9
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
71
A
ALA
0.71
0.38
0.43
9
74
A
ASP
0.64
0.32
0.53
8
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.70
10
3
A
GLY
0.62
0.41
0.46
9
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.62
10
6
A
LEU
0.50
0.70
0.46
10
8
A
LYS
0.44
0.25
0.62
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.28
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.61
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.62
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.69
10
26
A
ALA
0.53
0.38
0.50
1
27
A
LYS
0.72
0.25
0.52
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.22
10
30
A
LYS
0.68
0.25
0.60
9
31
A
GLY
0.84
0.41
0.60
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.33
8
43
A
GLY
0.64
0.41
0.46
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.47
9
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.64
10
51
A
GLY
0.64
0.41
0.68
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.63
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.46
3
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.36
8
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.57
9
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.66
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.54
6
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.46
9
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.25
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.66
10
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.51
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
8
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.47
9
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.49
10
37
A
LEU
0.67
0.70
0.11
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.32
7
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
9
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.47
5
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.70
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.64
10
51
A
GLY
0.64
0.41
0.68
10
52
A
GLU
0.60
0.33
0.74
10
53
A
ARG
0.42
0.51
0.62
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.60
9
63
A
LYS
0.43
0.25
0.57
9
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.66
8
68
A
GLU
0.71
0.33
0.51
9
71
A
ALA
0.71
0.38
0.44
4
74
A
ASP
0.64
0.32
0.52
6
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.69
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.59
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.22
10
16
A
ALA
0.56
0.38
0.64
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.61
10
22
A
ALA
0.47
0.38
0.45
4
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.67
10
25
A
SER
0.40
0.36
0.67
10
26
A
ALA
0.53
0.38
0.48
4
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.30
10
43
A
GLY
0.64
0.41
0.46
10
44
A
TYR
0.79
0.80
0.25
10
45
A
ALA
0.65
0.38
0.46
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.64
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.74
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.15
10
58
A
THR
0.58
0.33
0.44
9
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.33
10
62
A
LYS
0.42
0.25
0.59
10
63
A
LYS
0.43
0.25
0.59
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.50
10
70
A
LYS
0.56
0.25
0.53
10
71
A
ALA
0.71
0.38
0.43
8
74
A
ASP
0.64
0.32
0.51
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.48
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.67
10
4
A
ALA
0.41
0.38
0.58
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.55
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.63
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.48
1
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.57
10
29
A
VAL
0.77
0.56
0.22
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.33
8
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.47
9
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.58
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.60
10
54
A
LYS
0.52
0.25
0.61
8
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.32
4
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.42
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.65
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.52
6
71
A
ALA
0.71
0.38
0.45
8
74
A
ASP
0.64
0.32
0.55
9
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
2
A
ASP
0.37
0.32
0.64
10
3
A
GLY
0.62
0.41
0.54
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.24
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.70
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.48
2
27
A
LYS
0.72
0.25
0.59
8
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.41
10
33
A
GLY
0.51
0.41
0.52
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.51
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.33
10
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.70
10
53
A
ARG
0.42
0.51
0.61
10
54
A
LYS
0.52
0.25
0.59
9
55
A
ALA
0.44
0.38
0.62
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.18
10
58
A
THR
0.58
0.33
0.46
2
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.33
7
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.61
8
64
A
TYR
0.83
0.80
0.44
10
65
A
SER
0.61
0.36
0.62
4
66
A
ASP
0.69
0.32
0.64
9
67
A
GLU
0.49
0.33
0.70
4
68
A
GLU
0.71
0.33
0.53
10
74
A
ASP
0.64
0.32
0.53
9
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.67
10
3
A
GLY
0.62
0.41
0.45
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.68
10
17
A
ASP
0.52
0.32
0.62
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.69
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.65
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.48
1
27
A
LYS
0.72
0.25
0.54
9
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
8
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.50
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.31
7
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.31
10
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.60
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.59
10
54
A
LYS
0.52
0.25
0.61
7
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.33
6
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
6
64
A
TYR
0.83
0.80
0.44
10
65
A
SER
0.61
0.36
0.60
1
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
4
68
A
GLU
0.71
0.33
0.52
9
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.54
6
75
A
TYR
0.87
0.80
0.48
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.70
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.53
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.61
10
22
A
ALA
0.47
0.38
0.46
1
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.66
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.49
2
27
A
LYS
0.72
0.25
0.53
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.32
8
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.26
10
45
A
ALA
0.65
0.38
0.45
10
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.63
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.58
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.15
10
58
A
THR
0.58
0.33
0.44
7
59
A
ASN
0.61
0.39
0.56
10
60
A
ALA
0.58
0.38
0.32
9
62
A
LYS
0.42
0.25
0.58
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.54
9
71
A
ALA
0.71
0.38
0.44
6
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.76
10
2
A
ASP
0.37
0.32
0.68
10
3
A
GLY
0.62
0.41
0.55
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.55
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.62
10
22
A
ALA
0.47
0.38
0.48
1
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.63
10
25
A
SER
0.40
0.36
0.68
10
28
A
PRO
0.65
0.47
0.55
10
30
A
LYS
0.68
0.25
0.59
9
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.33
10
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.46
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.46
10
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.70
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.45
1
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.31
8
62
A
LYS
0.42
0.25
0.60
3
63
A
LYS
0.43
0.25
0.56
7
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.52
10
71
A
ALA
0.71
0.38
0.43
10
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.53
8
78
A
LYS
0.49
0.25
0.68
8
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
10
3
A
GLY
0.62
0.41
0.45
10
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.62
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.59
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.57
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.63
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.48
2
27
A
LYS
0.72
0.25
0.53
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.18
10
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.31
8
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.60
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.34
7
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.60
7
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.61
2
66
A
ASP
0.69
0.32
0.64
9
67
A
GLU
0.49
0.33
0.67
6
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.55
6
71
A
ALA
0.71
0.38
0.44
4
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.48
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.66
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.43
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.57
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.66
10
25
A
SER
0.40
0.36
0.67
10
26
A
ALA
0.53
0.38
0.48
1
27
A
LYS
0.72
0.25
0.53
8
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.30
9
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.65
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.50
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.70
10
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.31
6
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.57
6
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.59
2
66
A
ASP
0.69
0.32
0.63
9
67
A
GLU
0.49
0.33
0.66
4
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.54
9
71
A
ALA
0.71
0.38
0.43
3
74
A
ASP
0.64
0.32
0.52
8
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.46
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.63
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.61
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.59
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.31
6
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
8
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.66
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.49
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.67
9
53
A
ARG
0.42
0.51
0.63
10
54
A
LYS
0.52
0.25
0.58
7
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.46
1
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.34
6
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.60
6
64
A
TYR
0.83
0.80
0.40
10
66
A
ASP
0.69
0.32
0.66
9
67
A
GLU
0.49
0.33
0.66
9
68
A
GLU
0.71
0.33
0.52
9
70
A
LYS
0.56
0.25
0.53
7
71
A
ALA
0.71
0.38
0.43
2
74
A
ASP
0.64
0.32
0.52
7
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.65
10
2
A
ASP
0.37
0.32
0.69
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.68
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
10
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.50
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.32
6
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
3
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.66
10
48
A
SER
0.47
0.36
0.69
10
49
A
TYR
0.57
0.80
0.50
10
50
A
GLY
0.59
0.41
0.54
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.58
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.31
7
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.58
7
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
3
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.66
7
68
A
GLU
0.71
0.33
0.51
9
70
A
LYS
0.56
0.25
0.53
7
71
A
ALA
0.71
0.38
0.42
5
74
A
ASP
0.64
0.32
0.52
8
75
A
TYR
0.87
0.80
0.46
10
76
A
MET
0.63
0.66
0.08
10
77
A
SER
0.59
0.36
0.49
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.67
10
3
A
GLY
0.62
0.41
0.45
10
4
A
ALA
0.41
0.38
0.54
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.59
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
10
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.53
8
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.59
9
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.48
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.32
7
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.49
10
46
A
ASP
0.48
0.32
0.69
10
47
A
GLY
0.73
0.41
0.67
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.66
10
53
A
ARG
0.42
0.51
0.62
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.16
10
58
A
THR
0.58
0.33
0.46
1
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.32
7
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.53
7
71
A
ALA
0.71
0.38
0.44
2
74
A
ASP
0.64
0.32
0.54
8
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.66
10
2
A
ASP
0.37
0.32
0.66
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.43
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.56
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
10
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.51
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.57
7
31
A
GLY
0.84
0.41
0.52
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.46
10
37
A
LEU
0.67
0.70
0.10
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.31
4
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.48
2
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.65
9
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.32
2
62
A
LYS
0.42
0.25
0.61
6
63
A
LYS
0.43
0.25
0.57
2
64
A
TYR
0.83
0.80
0.42
10
66
A
ASP
0.69
0.32
0.62
6
68
A
GLU
0.71
0.33
0.51
10
74
A
ASP
0.64
0.32
0.52
7
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.69
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.52
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.61
10
20
A
LYS
0.78
0.25
0.69
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.65
9
25
A
SER
0.40
0.36
0.65
10
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
9
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.51
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.32
5
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.46
7
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
3
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.70
5
53
A
ARG
0.42
0.51
0.62
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.60
10
60
A
ALA
0.58
0.38
0.37
1
62
A
LYS
0.42
0.25
0.61
6
63
A
LYS
0.43
0.25
0.62
1
64
A
TYR
0.83
0.80
0.43
10
66
A
ASP
0.69
0.32
0.62
8
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.51
6
71
A
ALA
0.71
0.38
0.43
1
74
A
ASP
0.64
0.32
0.53
1
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.71
10
3
A
GLY
0.62
0.41
0.46
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.62
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.51
10
10
A
CYS
0.98
0.64
0.27
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.52
10
14
A
HIS
1.00
0.60
0.27
10
15
A
GLY
0.87
0.41
0.56
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
9
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.22
10
30
A
LYS
0.68
0.25
0.59
9
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.31
5
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.60
10
51
A
GLY
0.64
0.41
0.66
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.63
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.19
10
58
A
THR
0.58
0.33
0.46
2
59
A
ASN
0.61
0.39
0.61
10
60
A
ALA
0.58
0.38
0.40
8
62
A
LYS
0.42
0.25
0.58
9
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
71
A
ALA
0.71
0.38
0.45
1
74
A
ASP
0.64
0.32
0.53
8
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.70
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.70
10
3
A
GLY
0.62
0.41
0.45
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.62
10
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.51
10
16
A
ALA
0.56
0.38
0.62
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
9
25
A
SER
0.40
0.36
0.69
10
26
A
ALA
0.53
0.38
0.48
1
27
A
LYS
0.72
0.25
0.54
9
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.58
9
31
A
GLY
0.84
0.41
0.51
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.33
5
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.48
8
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.66
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.60
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.50
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.33
2
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
3
64
A
TYR
0.83
0.80
0.42
10
65
A
SER
0.61
0.36
0.60
1
66
A
ASP
0.69
0.32
0.61
9
67
A
GLU
0.49
0.33
0.66
4
68
A
GLU
0.71
0.33
0.52
7
71
A
ALA
0.71
0.38
0.44
4
74
A
ASP
0.64
0.32
0.53
8
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.66
10
3
A
GLY
0.62
0.41
0.43
2
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.57
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
9
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.68
10
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.56
5
31
A
GLY
0.84
0.41
0.52
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
9
35
A
GLU
0.45
0.33
0.60
10
36
A
GLU
0.82
0.33
0.44
10
37
A
LEU
0.67
0.70
0.08
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.32
3
43
A
GLY
0.64
0.41
0.47
5
44
A
TYR
0.79
0.80
0.26
10
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.67
10
48
A
SER
0.47
0.36
0.69
10
49
A
TYR
0.57
0.80
0.49
10
50
A
GLY
0.59
0.41
0.53
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.68
9
53
A
ARG
0.42
0.51
0.58
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.32
3
62
A
LYS
0.42
0.25
0.60
9
63
A
LYS
0.43
0.25
0.58
5
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
7
68
A
GLU
0.71
0.33
0.51
8
70
A
LYS
0.56
0.25
0.52
1
71
A
ALA
0.71
0.38
0.43
3
74
A
ASP
0.64
0.32
0.50
1
75
A
TYR
0.87
0.80
0.43
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.75
10
2
A
ASP
0.37
0.32
0.68
10
3
A
GLY
0.62
0.41
0.53
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.55
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.60
10
22
A
ALA
0.47
0.38
0.46
3
23
A
MET
0.53
0.66
0.65
10
24
A
GLY
0.52
0.41
0.65
10
25
A
SER
0.40
0.36
0.69
10
26
A
ALA
0.53
0.38
0.48
2
27
A
LYS
0.72
0.25
0.49
1
28
A
PRO
0.65
0.47
0.54
7
30
A
LYS
0.68
0.25
0.60
9
31
A
GLY
0.84
0.41
0.58
9
32
A
GLN
0.77
0.43
0.35
7
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
9
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.34
10
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.62
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.76
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
58
A
THR
0.58
0.33
0.45
9
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.31
10
62
A
LYS
0.42
0.25
0.59
5
63
A
LYS
0.43
0.25
0.58
8
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.51
10
71
A
ALA
0.71
0.38
0.41
10
74
A
ASP
0.64
0.32
0.52
10
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.50
9
78
A
LYS
0.49
0.25
0.65
9
79
A
LEU
0.60
0.70
0.55
9
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.66
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.41
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.46
10
14
A
HIS
1.00
0.60
0.20
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.56
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
22
A
ALA
0.47
0.38
0.45
1
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
10
25
A
SER
0.40
0.36
0.68
10
26
A
ALA
0.53
0.38
0.47
2
27
A
LYS
0.72
0.25
0.58
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.32
7
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.47
10
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.56
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.69
10
53
A
ARG
0.42
0.51
0.60
10
54
A
LYS
0.52
0.25
0.60
4
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.46
2
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.32
8
62
A
LYS
0.42
0.25
0.59
8
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.53
6
71
A
ALA
0.71
0.38
0.42
4
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.69
10
3
A
GLY
0.62
0.41
0.46
10
4
A
ALA
0.41
0.38
0.59
10
5
A
ALA
0.37
0.38
0.62
10
6
A
LEU
0.50
0.70
0.46
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.52
10
10
A
CYS
0.98
0.64
0.29
10
11
A
ILE
0.51
0.64
0.51
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.26
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.70
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.66
10
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.50
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.20
10
30
A
LYS
0.68
0.25
0.57
9
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.54
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.51
10
38
A
TYR
0.35
0.80
0.44
10
40
A
LYS
0.69
0.25
0.33
6
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.46
9
44
A
TYR
0.79
0.80
0.29
10
45
A
ALA
0.65
0.38
0.47
8
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.62
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.18
10
58
A
THR
0.58
0.33
0.46
1
59
A
ASN
0.61
0.39
0.61
10
60
A
ALA
0.58
0.38
0.39
8
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
10
64
A
TYR
0.83
0.80
0.42
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.69
9
68
A
GLU
0.71
0.33
0.53
9
71
A
ALA
0.71
0.38
0.44
1
74
A
ASP
0.64
0.32
0.54
8
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.50
10
2
A
ASP
0.37
0.32
0.69
10
3
A
GLY
0.62
0.41
0.56
10
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.51
10
10
A
CYS
0.98
0.64
0.29
10
11
A
ILE
0.51
0.64
0.51
10
12
A
GLY
0.57
0.41
0.61
10
13
A
CYS
0.99
0.64
0.52
10
14
A
HIS
1.00
0.60
0.27
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.70
10
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.54
8
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.59
8
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.47
5
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.50
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.31
4
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
8
44
A
TYR
0.79
0.80
0.31
10
45
A
ALA
0.65
0.38
0.48
9
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.71
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.60
10
52
A
GLU
0.60
0.33
0.71
10
53
A
ARG
0.42
0.51
0.62
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.57
10
57
A
MET
0.98
0.66
0.19
10
59
A
ASN
0.61
0.39
0.60
10
60
A
ALA
0.58
0.38
0.34
5
62
A
LYS
0.42
0.25
0.61
6
63
A
LYS
0.43
0.25
0.59
8
64
A
TYR
0.83
0.80
0.44
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.54
10
70
A
LYS
0.56
0.25
0.55
3
71
A
ALA
0.71
0.38
0.45
5
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.60
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.42
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.59
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.67
9
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.50
10
28
A
PRO
0.65
0.47
0.52
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.41
10
40
A
LYS
0.69
0.25
0.32
7
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
9
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.46
7
46
A
ASP
0.48
0.32
0.67
10
47
A
GLY
0.73
0.41
0.67
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.58
10
52
A
GLU
0.60
0.33
0.69
9
53
A
ARG
0.42
0.51
0.60
10
54
A
LYS
0.52
0.25
0.61
6
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.58
10
60
A
ALA
0.58
0.38
0.32
3
62
A
LYS
0.42
0.25
0.60
9
63
A
LYS
0.43
0.25
0.57
2
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.64
6
67
A
GLU
0.49
0.33
0.65
6
68
A
GLU
0.71
0.33
0.51
9
71
A
ALA
0.71
0.38
0.41
1
74
A
ASP
0.64
0.32
0.52
6
75
A
TYR
0.87
0.80
0.41
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.68
8
2
A
ASP
0.37
0.32
0.65
8
3
A
GLY
0.62
0.41
0.43
7
4
A
ALA
0.41
0.38
0.52
8
5
A
ALA
0.37
0.38
0.60
8
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.64
10
17
A
ASP
0.52
0.32
0.54
9
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.61
9
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.62
9
25
A
SER
0.40
0.36
0.67
9
27
A
LYS
0.72
0.25
0.57
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.18
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.34
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
9
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.31
5
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
9
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.46
2
46
A
ASP
0.48
0.32
0.70
10
47
A
GLY
0.73
0.41
0.68
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.50
10
50
A
GLY
0.59
0.41
0.55
10
51
A
GLY
0.64
0.41
0.57
10
52
A
GLU
0.60
0.33
0.67
10
53
A
ARG
0.42
0.51
0.57
10
54
A
LYS
0.52
0.25
0.59
6
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.48
10
57
A
MET
0.98
0.66
0.13
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
7
64
A
TYR
0.83
0.80
0.40
8
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.64
3
67
A
GLU
0.49
0.33
0.65
1
68
A
GLU
0.71
0.33
0.49
6
71
A
ALA
0.71
0.38
0.41
1
74
A
ASP
0.64
0.32
0.52
8
75
A
TYR
0.87
0.80
0.45
10
76
A
MET
0.63
0.66
0.07
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.72
10
3
A
GLY
0.62
0.41
0.47
10
4
A
ALA
0.41
0.38
0.57
10
5
A
ALA
0.37
0.38
0.62
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.67
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.70
10
25
A
SER
0.40
0.36
0.70
10
27
A
LYS
0.72
0.25
0.53
3
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.21
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.52
10
38
A
TYR
0.35
0.80
0.41
10
40
A
LYS
0.69
0.25
0.31
8
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.48
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
9
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.69
10
48
A
SER
0.47
0.36
0.72
10
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.63
10
51
A
GLY
0.64
0.41
0.67
10
52
A
GLU
0.60
0.33
0.76
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.16
10
58
A
THR
0.58
0.33
0.46
2
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.38
8
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.60
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.53
10
71
A
ALA
0.71
0.38
0.43
4
74
A
ASP
0.64
0.32
0.53
8
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.70
10
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.53
10
5
A
ALA
0.37
0.38
0.59
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.21
10
11
A
ILE
0.51
0.64
0.45
10
12
A
GLY
0.57
0.41
0.57
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.62
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
22
A
ALA
0.47
0.38
0.47
2
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.67
10
26
A
ALA
0.53
0.38
0.47
2
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.52
10
29
A
VAL
0.77
0.56
0.17
10
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.42
10
40
A
LYS
0.69
0.25
0.30
9
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.47
9
46
A
ASP
0.48
0.32
0.68
10
47
A
GLY
0.73
0.41
0.65
10
48
A
SER
0.47
0.36
0.70
10
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.57
10
51
A
GLY
0.64
0.41
0.59
10
52
A
GLU
0.60
0.33
0.67
10
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.15
10
58
A
THR
0.58
0.33
0.45
2
59
A
ASN
0.61
0.39
0.57
10
60
A
ALA
0.58
0.38
0.31
9
62
A
LYS
0.42
0.25
0.59
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.65
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.52
10
71
A
ALA
0.71
0.38
0.45
10
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.49
10
2
A
ASP
0.37
0.32
0.63
10
3
A
GLY
0.62
0.41
0.55
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.61
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.26
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
22
A
ALA
0.47
0.38
0.49
1
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.67
10
25
A
SER
0.40
0.36
0.69
10
26
A
ALA
0.53
0.38
0.51
3
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.22
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.59
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.50
10
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.45
10
40
A
LYS
0.69
0.25
0.35
9
41
A
MET
0.73
0.66
0.00
10
43
A
GLY
0.64
0.41
0.47
10
44
A
TYR
0.79
0.80
0.27
10
45
A
ALA
0.65
0.38
0.46
10
46
A
ASP
0.48
0.32
0.66
10
47
A
GLY
0.73
0.41
0.67
10
48
A
SER
0.47
0.36
0.73
10
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.66
10
51
A
GLY
0.64
0.41
0.68
10
52
A
GLU
0.60
0.33
0.77
10
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.16
10
58
A
THR
0.58
0.33
0.45
5
59
A
ASN
0.61
0.39
0.59
10
60
A
ALA
0.58
0.38
0.33
9
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.59
9
64
A
TYR
0.83
0.80
0.43
10
65
A
SER
0.61
0.36
0.60
2
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.69
3
68
A
GLU
0.71
0.33
0.54
10
70
A
LYS
0.56
0.25
0.55
10
71
A
ALA
0.71
0.38
0.44
1
74
A
ASP
0.64
0.32
0.55
9
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.53
10