Pre-computed interfaces

How to use JET2 Viewer

References

Contact

JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1DVH chain A sc2

 

Download file

 

 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
3
3
A
GLY
0.62
0.41
0.45
7
4
A
ALA
0.41
0.38
0.54
7
5
A
ALA
0.37
0.38
0.61
3
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
2
25
A
SER
0.40
0.36
0.67
5
27
A
LYS
0.72
0.25
0.51
4
28
A
PRO
0.65
0.47
0.53
10
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.47
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.61
5
36
A
GLU
0.82
0.33
0.49
10
37
A
LEU
0.67
0.70
0.11
10
38
A
TYR
0.35
0.80
0.41
10
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.29
10
46
A
ASP
0.48
0.32
0.67
3
47
A
GLY
0.73
0.41
0.68
3
48
A
SER
0.47
0.36
0.71
3
49
A
TYR
0.57
0.80
0.51
6
50
A
GLY
0.59
0.41
0.56
3
51
A
GLY
0.64
0.41
0.59
3
52
A
GLU
0.60
0.33
0.66
2
53
A
ARG
0.42
0.51
0.60
10
54
A
LYS
0.52
0.25
0.58
2
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.60
10
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.38
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.53
10
71
A
ALA
0.71
0.38
0.42
3
74
A
ASP
0.64
0.32
0.52
10
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.49
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.66
2
3
A
GLY
0.62
0.41
0.44
9
4
A
ALA
0.41
0.38
0.57
9
5
A
ALA
0.37
0.38
0.60
5
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.65
2
25
A
SER
0.40
0.36
0.65
9
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.21
6
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
8
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.45
9
43
A
GLY
0.64
0.41
0.47
2
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
1
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.66
2
48
A
SER
0.47
0.36
0.72
2
49
A
TYR
0.57
0.80
0.50
9
50
A
GLY
0.59
0.41
0.55
2
51
A
GLY
0.64
0.41
0.59
1
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.60
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.59
9
64
A
TYR
0.83
0.80
0.40
3
65
A
SER
0.61
0.36
0.61
3
66
A
ASP
0.69
0.32
0.64
3
67
A
GLU
0.49
0.33
0.66
3
68
A
GLU
0.71
0.33
0.52
3
70
A
LYS
0.56
0.25
0.56
8
74
A
ASP
0.64
0.32
0.52
9
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
2
A
ASP
0.37
0.32
0.66
8
3
A
GLY
0.62
0.41
0.51
10
4
A
ALA
0.41
0.38
0.52
10
5
A
ALA
0.37
0.38
0.59
1
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.46
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.60
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
2
25
A
SER
0.40
0.36
0.67
5
27
A
LYS
0.72
0.25
0.50
3
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.16
5
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.46
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.61
6
36
A
GLU
0.82
0.33
0.48
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.53
1
43
A
GLY
0.64
0.41
0.46
3
44
A
TYR
0.79
0.80
0.27
10
46
A
ASP
0.48
0.32
0.66
2
47
A
GLY
0.73
0.41
0.67
2
48
A
SER
0.47
0.36
0.70
2
49
A
TYR
0.57
0.80
0.49
4
50
A
GLY
0.59
0.41
0.56
2
51
A
GLY
0.64
0.41
0.58
2
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.14
10
59
A
ASN
0.61
0.39
0.56
10
62
A
LYS
0.42
0.25
0.58
9
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.65
10
68
A
GLU
0.71
0.33
0.50
10
70
A
LYS
0.56
0.25
0.52
5
71
A
ALA
0.71
0.38
0.40
2
74
A
ASP
0.64
0.32
0.50
10
75
A
TYR
0.87
0.80
0.42
10
77
A
SER
0.59
0.36
0.48
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.67
5
4
A
ALA
0.41
0.38
0.57
7
5
A
ALA
0.37
0.38
0.61
1
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.60
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.69
2
25
A
SER
0.40
0.36
0.68
7
27
A
LYS
0.72
0.25
0.51
7
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.17
4
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
9
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
43
A
GLY
0.64
0.41
0.46
6
44
A
TYR
0.79
0.80
0.28
10
45
A
ALA
0.65
0.38
0.48
10
46
A
ASP
0.48
0.32
0.67
6
47
A
GLY
0.73
0.41
0.68
6
48
A
SER
0.47
0.36
0.71
6
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.57
6
51
A
GLY
0.64
0.41
0.59
7
53
A
ARG
0.42
0.51
0.62
10
54
A
LYS
0.52
0.25
0.61
10
55
A
ALA
0.44
0.38
0.62
10
56
A
MET
0.56
0.66
0.52
10
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.58
10
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.53
5
71
A
ALA
0.71
0.38
0.43
5
74
A
ASP
0.64
0.32
0.52
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
1
4
A
ALA
0.41
0.38
0.54
7
5
A
ALA
0.37
0.38
0.61
8
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.59
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.67
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.64
4
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.50
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
4
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.32
10
33
A
GLY
0.51
0.41
0.47
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.44
10
39
A
LYS
0.54
0.25
0.54
2
40
A
LYS
0.69
0.25
0.33
2
43
A
GLY
0.64
0.41
0.47
9
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.68
9
47
A
GLY
0.73
0.41
0.69
9
48
A
SER
0.47
0.36
0.71
9
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.55
9
51
A
GLY
0.64
0.41
0.59
9
53
A
ARG
0.42
0.51
0.58
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.59
3
64
A
TYR
0.83
0.80
0.39
1
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.62
1
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.50
1
74
A
ASP
0.64
0.32
0.53
6
75
A
TYR
0.87
0.80
0.47
10
76
A
MET
0.63
0.66
0.08
9
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.80
2
2
A
ASP
0.37
0.32
0.71
3
3
A
GLY
0.62
0.41
0.58
8
4
A
ALA
0.41
0.38
0.57
8
5
A
ALA
0.37
0.38
0.61
2
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.27
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.51
10
14
A
HIS
1.00
0.60
0.28
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.69
10
24
A
GLY
0.52
0.41
0.69
10
25
A
SER
0.40
0.36
0.70
10
27
A
LYS
0.72
0.25
0.52
5
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.20
2
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
8
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.45
10
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.28
7
46
A
ASP
0.48
0.32
0.67
3
47
A
GLY
0.73
0.41
0.68
3
48
A
SER
0.47
0.36
0.72
3
49
A
TYR
0.57
0.80
0.52
6
50
A
GLY
0.59
0.41
0.65
3
51
A
GLY
0.64
0.41
0.68
2
52
A
GLU
0.60
0.33
0.77
2
53
A
ARG
0.42
0.51
0.61
7
55
A
ALA
0.44
0.38
0.59
7
56
A
MET
0.56
0.66
0.55
7
57
A
MET
0.98
0.66
0.17
9
59
A
ASN
0.61
0.39
0.59
7
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.57
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.55
4
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.55
10
75
A
TYR
0.87
0.80
0.49
10
77
A
SER
0.59
0.36
0.48
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.67
1
2
A
ASP
0.37
0.32
0.71
1
3
A
GLY
0.62
0.41
0.46
3
4
A
ALA
0.41
0.38
0.57
4
5
A
ALA
0.37
0.38
0.61
1
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.44
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.61
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.64
10
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.21
2
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.54
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.54
1
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.27
8
46
A
ASP
0.48
0.32
0.66
3
47
A
GLY
0.73
0.41
0.69
3
48
A
SER
0.47
0.36
0.71
3
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.64
3
51
A
GLY
0.64
0.41
0.67
3
52
A
GLU
0.60
0.33
0.76
1
53
A
ARG
0.42
0.51
0.65
7
55
A
ALA
0.44
0.38
0.57
7
56
A
MET
0.56
0.66
0.53
7
57
A
MET
0.98
0.66
0.14
6
59
A
ASN
0.61
0.39
0.57
6
62
A
LYS
0.42
0.25
0.60
7
63
A
LYS
0.43
0.25
0.59
2
64
A
TYR
0.83
0.80
0.40
2
65
A
SER
0.61
0.36
0.60
2
66
A
ASP
0.69
0.32
0.62
2
67
A
GLU
0.49
0.33
0.66
2
68
A
GLU
0.71
0.33
0.52
2
70
A
LYS
0.56
0.25
0.52
1
71
A
ALA
0.71
0.38
0.44
1
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.54
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.71
6
3
A
GLY
0.62
0.41
0.45
8
4
A
ALA
0.41
0.38
0.55
3
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
3
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.53
10
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.20
5
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.60
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.48
7
44
A
TYR
0.79
0.80
0.30
10
45
A
ALA
0.65
0.38
0.49
3
46
A
ASP
0.48
0.32
0.67
7
47
A
GLY
0.73
0.41
0.68
7
48
A
SER
0.47
0.36
0.72
7
49
A
TYR
0.57
0.80
0.52
10
50
A
GLY
0.59
0.41
0.56
7
51
A
GLY
0.64
0.41
0.60
4
53
A
ARG
0.42
0.51
0.63
10
54
A
LYS
0.52
0.25
0.60
10
55
A
ALA
0.44
0.38
0.62
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.58
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.54
4
71
A
ALA
0.71
0.38
0.45
6
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.55
10
2
A
ASP
0.37
0.32
0.68
2
3
A
GLY
0.62
0.41
0.54
10
4
A
ALA
0.41
0.38
0.54
10
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.58
9
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.66
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
4
25
A
SER
0.40
0.36
0.69
9
27
A
LYS
0.72
0.25
0.49
8
28
A
PRO
0.65
0.47
0.52
10
29
A
VAL
0.77
0.56
0.19
4
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.48
9
35
A
GLU
0.45
0.33
0.63
8
36
A
GLU
0.82
0.33
0.48
9
38
A
TYR
0.35
0.80
0.44
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.48
3
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.67
3
47
A
GLY
0.73
0.41
0.68
3
48
A
SER
0.47
0.36
0.71
3
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.65
3
51
A
GLY
0.64
0.41
0.69
3
52
A
GLU
0.60
0.33
0.77
1
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.59
9
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.60
10
62
A
LYS
0.42
0.25
0.57
9
63
A
LYS
0.43
0.25
0.55
9
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.54
5
71
A
ALA
0.71
0.38
0.43
2
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.69
8
2
A
ASP
0.37
0.32
0.70
3
3
A
GLY
0.62
0.41
0.46
8
4
A
ALA
0.41
0.38
0.55
8
5
A
ALA
0.37
0.38
0.62
4
6
A
LEU
0.50
0.70
0.46
10
8
A
LYS
0.44
0.25
0.62
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.28
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.61
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.62
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
2
25
A
SER
0.40
0.36
0.69
6
27
A
LYS
0.72
0.25
0.52
5
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.22
4
30
A
LYS
0.68
0.25
0.60
10
31
A
GLY
0.84
0.41
0.60
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.49
9
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.56
1
43
A
GLY
0.64
0.41
0.46
3
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.66
2
47
A
GLY
0.73
0.41
0.68
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.53
5
50
A
GLY
0.59
0.41
0.64
2
51
A
GLY
0.64
0.41
0.68
2
52
A
GLU
0.60
0.33
0.77
1
53
A
ARG
0.42
0.51
0.63
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.59
10
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.57
9
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.66
10
67
A
GLU
0.49
0.33
0.67
8
68
A
GLU
0.71
0.33
0.53
9
70
A
LYS
0.56
0.25
0.54
4
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
9
2
A
ASP
0.37
0.32
0.71
5
3
A
GLY
0.62
0.41
0.46
8
4
A
ALA
0.41
0.38
0.57
7
5
A
ALA
0.37
0.38
0.61
1
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.25
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.66
2
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.51
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
2
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.61
10
36
A
GLU
0.82
0.33
0.49
10
37
A
LEU
0.67
0.70
0.11
10
38
A
TYR
0.35
0.80
0.43
10
43
A
GLY
0.64
0.41
0.47
1
44
A
TYR
0.79
0.80
0.28
3
46
A
ASP
0.48
0.32
0.67
1
47
A
GLY
0.73
0.41
0.70
1
48
A
SER
0.47
0.36
0.72
1
49
A
TYR
0.57
0.80
0.52
1
50
A
GLY
0.59
0.41
0.64
1
51
A
GLY
0.64
0.41
0.68
1
52
A
GLU
0.60
0.33
0.74
1
53
A
ARG
0.42
0.51
0.62
3
55
A
ALA
0.44
0.38
0.59
3
56
A
MET
0.56
0.66
0.54
3
57
A
MET
0.98
0.66
0.15
3
59
A
ASN
0.61
0.39
0.57
4
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.51
1
71
A
ALA
0.71
0.38
0.44
5
74
A
ASP
0.64
0.32
0.52
9
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.69
9
2
A
ASP
0.37
0.32
0.69
4
3
A
GLY
0.62
0.41
0.44
9
4
A
ALA
0.41
0.38
0.55
9
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.22
10
16
A
ALA
0.56
0.38
0.64
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.67
1
25
A
SER
0.40
0.36
0.67
9
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
2
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.54
1
43
A
GLY
0.64
0.41
0.46
2
44
A
TYR
0.79
0.80
0.25
6
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.68
2
48
A
SER
0.47
0.36
0.72
2
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.64
2
51
A
GLY
0.64
0.41
0.67
2
52
A
GLU
0.60
0.33
0.74
1
53
A
ARG
0.42
0.51
0.61
5
55
A
ALA
0.44
0.38
0.59
6
56
A
MET
0.56
0.66
0.55
6
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.59
7
62
A
LYS
0.42
0.25
0.59
10
63
A
LYS
0.43
0.25
0.59
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.50
10
70
A
LYS
0.56
0.25
0.53
9
71
A
ALA
0.71
0.38
0.43
4
74
A
ASP
0.64
0.32
0.51
9
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.48
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.67
7
4
A
ALA
0.41
0.38
0.58
5
5
A
ALA
0.37
0.38
0.60
1
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.55
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.63
2
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.57
10
29
A
VAL
0.77
0.56
0.22
3
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
7
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
40
A
LYS
0.69
0.25
0.33
1
43
A
GLY
0.64
0.41
0.48
1
44
A
TYR
0.79
0.80
0.29
6
49
A
TYR
0.57
0.80
0.53
1
53
A
ARG
0.42
0.51
0.60
6
54
A
LYS
0.52
0.25
0.61
6
55
A
ALA
0.44
0.38
0.61
6
56
A
MET
0.56
0.66
0.55
6
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.59
6
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.42
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.65
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.52
10
71
A
ALA
0.71
0.38
0.45
10
74
A
ASP
0.64
0.32
0.55
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
2
A
ASP
0.37
0.32
0.64
3
3
A
GLY
0.62
0.41
0.54
4
4
A
ALA
0.41
0.38
0.55
4
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.24
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.70
2
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.59
10
28
A
PRO
0.65
0.47
0.56
10
29
A
VAL
0.77
0.56
0.21
1
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.41
10
33
A
GLY
0.51
0.41
0.52
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.51
10
38
A
TYR
0.35
0.80
0.44
10
43
A
GLY
0.64
0.41
0.47
2
44
A
TYR
0.79
0.80
0.29
9
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.69
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.52
2
50
A
GLY
0.59
0.41
0.56
1
53
A
ARG
0.42
0.51
0.61
9
54
A
LYS
0.52
0.25
0.59
9
55
A
ALA
0.44
0.38
0.62
9
56
A
MET
0.56
0.66
0.56
9
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.59
9
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.61
2
64
A
TYR
0.83
0.80
0.44
2
65
A
SER
0.61
0.36
0.62
3
66
A
ASP
0.69
0.32
0.64
3
67
A
GLU
0.49
0.33
0.70
3
68
A
GLU
0.71
0.33
0.53
3
71
A
ALA
0.71
0.38
0.43
1
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.67
1
2
A
ASP
0.37
0.32
0.67
1
3
A
GLY
0.62
0.41
0.45
3
4
A
ALA
0.41
0.38
0.55
5
5
A
ALA
0.37
0.38
0.61
2
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.68
10
17
A
ASP
0.52
0.32
0.62
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.69
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.65
1
25
A
SER
0.40
0.36
0.68
8
27
A
LYS
0.72
0.25
0.54
8
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.19
2
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.50
10
38
A
TYR
0.35
0.80
0.43
8
43
A
GLY
0.64
0.41
0.48
3
44
A
TYR
0.79
0.80
0.31
10
46
A
ASP
0.48
0.32
0.68
3
47
A
GLY
0.73
0.41
0.69
3
48
A
SER
0.47
0.36
0.72
3
49
A
TYR
0.57
0.80
0.52
8
50
A
GLY
0.59
0.41
0.56
3
51
A
GLY
0.64
0.41
0.60
3
52
A
GLU
0.60
0.33
0.69
1
53
A
ARG
0.42
0.51
0.59
10
54
A
LYS
0.52
0.25
0.61
9
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.58
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
1
65
A
SER
0.61
0.36
0.60
1
66
A
ASP
0.69
0.32
0.64
1
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.52
1
70
A
LYS
0.56
0.25
0.53
1
71
A
ALA
0.71
0.38
0.44
1
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.48
9
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
9
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.70
2
3
A
GLY
0.62
0.41
0.44
6
4
A
ALA
0.41
0.38
0.53
6
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.66
2
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.20
5
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
9
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.26
5
46
A
ASP
0.48
0.32
0.66
2
47
A
GLY
0.73
0.41
0.68
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.63
2
51
A
GLY
0.64
0.41
0.67
2
53
A
ARG
0.42
0.51
0.61
4
55
A
ALA
0.44
0.38
0.58
4
56
A
MET
0.56
0.66
0.53
4
57
A
MET
0.98
0.66
0.15
9
59
A
ASN
0.61
0.39
0.56
4
62
A
LYS
0.42
0.25
0.58
9
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.54
9
71
A
ALA
0.71
0.38
0.44
2
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.50
10
2
A
ASP
0.37
0.32
0.68
3
3
A
GLY
0.62
0.41
0.55
8
4
A
ALA
0.41
0.38
0.55
8
5
A
ALA
0.37
0.38
0.60
1
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.55
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.68
10
24
A
GLY
0.52
0.41
0.63
9
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.55
9
28
A
PRO
0.65
0.47
0.55
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.44
10
44
A
TYR
0.79
0.80
0.28
5
53
A
ARG
0.42
0.51
0.61
5
55
A
ALA
0.44
0.38
0.61
5
56
A
MET
0.56
0.66
0.56
5
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.59
5
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.68
9
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.54
4
71
A
ALA
0.71
0.38
0.43
3
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.69
1
3
A
GLY
0.62
0.41
0.45
3
4
A
ALA
0.41
0.38
0.54
3
5
A
ALA
0.37
0.38
0.62
1
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.47
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.24
10
15
A
GLY
0.87
0.41
0.59
10
16
A
ALA
0.56
0.38
0.67
10
17
A
ASP
0.52
0.32
0.57
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.63
2
25
A
SER
0.40
0.36
0.68
8
27
A
LYS
0.72
0.25
0.53
8
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.18
2
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.48
10
35
A
GLU
0.45
0.33
0.62
9
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.44
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.47
4
44
A
TYR
0.79
0.80
0.29
10
46
A
ASP
0.48
0.32
0.67
3
47
A
GLY
0.73
0.41
0.68
3
48
A
SER
0.47
0.36
0.71
3
49
A
TYR
0.57
0.80
0.52
9
50
A
GLY
0.59
0.41
0.56
3
51
A
GLY
0.64
0.41
0.60
2
53
A
ARG
0.42
0.51
0.61
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
5
64
A
TYR
0.83
0.80
0.41
2
65
A
SER
0.61
0.36
0.61
2
66
A
ASP
0.69
0.32
0.64
2
67
A
GLU
0.49
0.33
0.67
2
68
A
GLU
0.71
0.33
0.53
2
70
A
LYS
0.56
0.25
0.55
6
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.48
10
1
A
ALA
0.20
0.38
0.68
1
2
A
ASP
0.37
0.32
0.66
1
3
A
GLY
0.62
0.41
0.44
6
4
A
ALA
0.41
0.38
0.54
7
5
A
ALA
0.37
0.38
0.60
2
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.43
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.57
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.66
2
25
A
SER
0.40
0.36
0.67
9
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.20
4
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
8
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.27
10
46
A
ASP
0.48
0.32
0.68
2
47
A
GLY
0.73
0.41
0.65
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.50
9
50
A
GLY
0.59
0.41
0.55
2
51
A
GLY
0.64
0.41
0.59
2
53
A
ARG
0.42
0.51
0.60
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.57
2
64
A
TYR
0.83
0.80
0.41
1
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.63
1
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.52
1
70
A
LYS
0.56
0.25
0.54
6
71
A
ALA
0.71
0.38
0.43
1
74
A
ASP
0.64
0.32
0.52
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.67
7
2
A
ASP
0.37
0.32
0.71
6
3
A
GLY
0.62
0.41
0.46
8
4
A
ALA
0.41
0.38
0.57
8
5
A
ALA
0.37
0.38
0.63
3
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.61
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
3
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.53
10
29
A
VAL
0.77
0.56
0.19
7
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.59
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.42
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.48
2
44
A
TYR
0.79
0.80
0.27
10
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.66
2
48
A
SER
0.47
0.36
0.70
2
49
A
TYR
0.57
0.80
0.49
9
50
A
GLY
0.59
0.41
0.56
2
51
A
GLY
0.64
0.41
0.58
9
52
A
GLU
0.60
0.33
0.67
1
53
A
ARG
0.42
0.51
0.63
10
54
A
LYS
0.52
0.25
0.58
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.56
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.60
7
64
A
TYR
0.83
0.80
0.40
7
65
A
SER
0.61
0.36
0.61
7
66
A
ASP
0.69
0.32
0.66
7
67
A
GLU
0.49
0.33
0.66
7
68
A
GLU
0.71
0.33
0.52
7
70
A
LYS
0.56
0.25
0.53
8
71
A
ALA
0.71
0.38
0.43
6
74
A
ASP
0.64
0.32
0.52
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
3
A
GLY
0.62
0.41
0.44
3
4
A
ALA
0.41
0.38
0.54
6
5
A
ALA
0.37
0.38
0.60
5
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.68
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
7
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.52
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
6
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.36
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.64
8
36
A
GLU
0.82
0.33
0.50
10
38
A
TYR
0.35
0.80
0.43
8
39
A
LYS
0.54
0.25
0.54
1
43
A
GLY
0.64
0.41
0.47
5
44
A
TYR
0.79
0.80
0.27
9
46
A
ASP
0.48
0.32
0.68
4
47
A
GLY
0.73
0.41
0.66
4
48
A
SER
0.47
0.36
0.69
4
49
A
TYR
0.57
0.80
0.50
9
50
A
GLY
0.59
0.41
0.54
4
51
A
GLY
0.64
0.41
0.58
4
52
A
GLU
0.60
0.33
0.69
1
53
A
ARG
0.42
0.51
0.58
9
54
A
LYS
0.52
0.25
0.59
1
55
A
ALA
0.44
0.38
0.60
9
56
A
MET
0.56
0.66
0.55
9
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.58
9
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.58
2
70
A
LYS
0.56
0.25
0.53
2
74
A
ASP
0.64
0.32
0.52
6
75
A
TYR
0.87
0.80
0.46
10
76
A
MET
0.63
0.66
0.08
10
77
A
SER
0.59
0.36
0.49
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.68
10
2
A
ASP
0.37
0.32
0.67
3
3
A
GLY
0.62
0.41
0.45
6
4
A
ALA
0.41
0.38
0.54
6
5
A
ALA
0.37
0.38
0.60
1
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.23
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.59
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
1
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.53
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.21
5
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.53
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
10
36
A
GLU
0.82
0.33
0.48
10
38
A
TYR
0.35
0.80
0.43
10
43
A
GLY
0.64
0.41
0.48
5
44
A
TYR
0.79
0.80
0.29
9
46
A
ASP
0.48
0.32
0.69
5
47
A
GLY
0.73
0.41
0.67
5
48
A
SER
0.47
0.36
0.70
5
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.56
5
51
A
GLY
0.64
0.41
0.59
5
52
A
GLU
0.60
0.33
0.66
1
53
A
ARG
0.42
0.51
0.62
7
54
A
LYS
0.52
0.25
0.58
1
55
A
ALA
0.44
0.38
0.61
7
56
A
MET
0.56
0.66
0.55
7
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.57
7
62
A
LYS
0.42
0.25
0.62
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.52
10
70
A
LYS
0.56
0.25
0.53
10
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.66
1
3
A
GLY
0.62
0.41
0.44
3
4
A
ALA
0.41
0.38
0.55
3
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.43
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.56
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.55
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.68
3
25
A
SER
0.40
0.36
0.67
9
27
A
LYS
0.72
0.25
0.51
9
28
A
PRO
0.65
0.47
0.54
10
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.52
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.62
8
36
A
GLU
0.82
0.33
0.46
10
37
A
LEU
0.67
0.70
0.10
10
38
A
TYR
0.35
0.80
0.42
6
39
A
LYS
0.54
0.25
0.53
1
43
A
GLY
0.64
0.41
0.47
6
44
A
TYR
0.79
0.80
0.29
10
46
A
ASP
0.48
0.32
0.67
5
47
A
GLY
0.73
0.41
0.69
5
48
A
SER
0.47
0.36
0.70
5
49
A
TYR
0.57
0.80
0.51
9
50
A
GLY
0.59
0.41
0.55
5
51
A
GLY
0.64
0.41
0.59
5
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.54
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.57
4
64
A
TYR
0.83
0.80
0.42
1
65
A
SER
0.61
0.36
0.59
1
66
A
ASP
0.69
0.32
0.62
1
67
A
GLU
0.49
0.33
0.66
1
68
A
GLU
0.71
0.33
0.51
1
70
A
LYS
0.56
0.25
0.53
1
74
A
ASP
0.64
0.32
0.52
9
75
A
TYR
0.87
0.80
0.45
9
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.69
9
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.69
2
2
A
ASP
0.37
0.32
0.67
2
3
A
GLY
0.62
0.41
0.44
9
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.61
2
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.52
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.61
10
20
A
LYS
0.78
0.25
0.69
10
21
A
ALA
0.43
0.38
0.61
9
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.65
2
25
A
SER
0.40
0.36
0.65
6
27
A
LYS
0.72
0.25
0.53
6
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.19
1
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.48
9
35
A
GLU
0.45
0.33
0.62
9
36
A
GLU
0.82
0.33
0.51
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.54
1
43
A
GLY
0.64
0.41
0.46
1
44
A
TYR
0.79
0.80
0.27
10
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.68
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.51
6
50
A
GLY
0.59
0.41
0.55
2
51
A
GLY
0.64
0.41
0.58
2
53
A
ARG
0.42
0.51
0.62
10
55
A
ALA
0.44
0.38
0.61
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.17
10
59
A
ASN
0.61
0.39
0.60
10
62
A
LYS
0.42
0.25
0.61
9
63
A
LYS
0.43
0.25
0.62
2
64
A
TYR
0.83
0.80
0.43
2
65
A
SER
0.61
0.36
0.60
2
66
A
ASP
0.69
0.32
0.62
2
67
A
GLU
0.49
0.33
0.66
2
68
A
GLU
0.71
0.33
0.51
2
70
A
LYS
0.56
0.25
0.51
1
71
A
ALA
0.71
0.38
0.43
2
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.71
5
3
A
GLY
0.62
0.41
0.46
10
4
A
ALA
0.41
0.38
0.57
10
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.51
10
10
A
CYS
0.98
0.64
0.27
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.52
10
14
A
HIS
1.00
0.60
0.27
10
15
A
GLY
0.87
0.41
0.56
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
2
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.53
9
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.22
2
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.49
9
35
A
GLU
0.45
0.33
0.62
7
36
A
GLU
0.82
0.33
0.49
9
38
A
TYR
0.35
0.80
0.44
10
39
A
LYS
0.54
0.25
0.56
1
43
A
GLY
0.64
0.41
0.48
3
44
A
TYR
0.79
0.80
0.27
9
46
A
ASP
0.48
0.32
0.67
3
47
A
GLY
0.73
0.41
0.69
3
48
A
SER
0.47
0.36
0.72
3
49
A
TYR
0.57
0.80
0.53
10
50
A
GLY
0.59
0.41
0.60
3
51
A
GLY
0.64
0.41
0.66
3
52
A
GLU
0.60
0.33
0.77
1
53
A
ARG
0.42
0.51
0.63
8
55
A
ALA
0.44
0.38
0.60
8
56
A
MET
0.56
0.66
0.56
8
57
A
MET
0.98
0.66
0.19
9
59
A
ASN
0.61
0.39
0.61
8
60
A
ALA
0.58
0.38
0.40
8
62
A
LYS
0.42
0.25
0.58
8
63
A
LYS
0.43
0.25
0.57
9
64
A
TYR
0.83
0.80
0.39
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.52
2
71
A
ALA
0.71
0.38
0.45
5
74
A
ASP
0.64
0.32
0.53
9
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.70
10
79
A
LEU
0.60
0.70
0.51
10
1
A
ALA
0.20
0.38
0.67
4
2
A
ASP
0.37
0.32
0.70
4
3
A
GLY
0.62
0.41
0.45
8
4
A
ALA
0.41
0.38
0.57
8
5
A
ALA
0.37
0.38
0.60
2
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.62
10
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.26
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.51
10
16
A
ALA
0.56
0.38
0.62
10
17
A
ASP
0.52
0.32
0.65
10
19
A
SER
0.44
0.36
0.66
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
1
25
A
SER
0.40
0.36
0.69
9
27
A
LYS
0.72
0.25
0.54
9
28
A
PRO
0.65
0.47
0.56
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.51
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.61
9
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.43
10
39
A
LYS
0.54
0.25
0.54
1
43
A
GLY
0.64
0.41
0.48
1
44
A
TYR
0.79
0.80
0.29
10
49
A
TYR
0.57
0.80
0.51
9
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.50
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.59
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
4
64
A
TYR
0.83
0.80
0.42
4
65
A
SER
0.61
0.36
0.60
4
66
A
ASP
0.69
0.32
0.61
4
67
A
GLU
0.49
0.33
0.66
4
68
A
GLU
0.71
0.33
0.52
4
70
A
LYS
0.56
0.25
0.53
3
71
A
ALA
0.71
0.38
0.44
4
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.49
10
1
A
ALA
0.20
0.38
0.67
10
2
A
ASP
0.37
0.32
0.66
2
3
A
GLY
0.62
0.41
0.43
10
4
A
ALA
0.41
0.38
0.56
10
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.57
10
9
A
SER
0.52
0.36
0.50
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.68
2
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.52
9
28
A
PRO
0.65
0.47
0.54
10
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.52
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.60
8
36
A
GLU
0.82
0.33
0.44
8
37
A
LEU
0.67
0.70
0.08
10
38
A
TYR
0.35
0.80
0.42
10
43
A
GLY
0.64
0.41
0.47
1
44
A
TYR
0.79
0.80
0.26
10
46
A
ASP
0.48
0.32
0.68
1
47
A
GLY
0.73
0.41
0.67
1
48
A
SER
0.47
0.36
0.69
1
49
A
TYR
0.57
0.80
0.49
9
50
A
GLY
0.59
0.41
0.53
1
51
A
GLY
0.64
0.41
0.58
1
53
A
ARG
0.42
0.51
0.58
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.58
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.61
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.52
10
71
A
ALA
0.71
0.38
0.43
2
74
A
ASP
0.64
0.32
0.50
10
75
A
TYR
0.87
0.80
0.43
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.49
10
2
A
ASP
0.37
0.32
0.68
2
3
A
GLY
0.62
0.41
0.53
10
4
A
ALA
0.41
0.38
0.55
10
5
A
ALA
0.37
0.38
0.61
1
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.49
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.55
10
16
A
ALA
0.56
0.38
0.65
10
17
A
ASP
0.52
0.32
0.64
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.65
10
24
A
GLY
0.52
0.41
0.65
2
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.49
8
28
A
PRO
0.65
0.47
0.54
10
30
A
LYS
0.68
0.25
0.60
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.35
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
8
38
A
TYR
0.35
0.80
0.42
10
43
A
GLY
0.64
0.41
0.48
5
44
A
TYR
0.79
0.80
0.29
10
46
A
ASP
0.48
0.32
0.67
6
47
A
GLY
0.73
0.41
0.69
6
48
A
SER
0.47
0.36
0.71
6
49
A
TYR
0.57
0.80
0.52
9
50
A
GLY
0.59
0.41
0.62
6
51
A
GLY
0.64
0.41
0.67
5
53
A
ARG
0.42
0.51
0.61
9
55
A
ALA
0.44
0.38
0.59
9
56
A
MET
0.56
0.66
0.54
9
57
A
MET
0.98
0.66
0.15
9
59
A
ASN
0.61
0.39
0.58
9
62
A
LYS
0.42
0.25
0.59
5
63
A
LYS
0.43
0.25
0.58
6
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.58
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.51
9
70
A
LYS
0.56
0.25
0.52
6
71
A
ALA
0.71
0.38
0.41
2
74
A
ASP
0.64
0.32
0.52
7
75
A
TYR
0.87
0.80
0.44
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.55
10
1
A
ALA
0.20
0.38
0.70
10
2
A
ASP
0.37
0.32
0.66
10
4
A
ALA
0.41
0.38
0.55
8
6
A
LEU
0.50
0.70
0.41
10
8
A
LYS
0.44
0.25
0.58
10
9
A
SER
0.52
0.36
0.46
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.46
10
14
A
HIS
1.00
0.60
0.20
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.56
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.64
2
25
A
SER
0.40
0.36
0.68
10
27
A
LYS
0.72
0.25
0.58
10
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.19
5
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.37
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
9
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.44
10
43
A
GLY
0.64
0.41
0.47
2
44
A
TYR
0.79
0.80
0.28
9
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.68
2
48
A
SER
0.47
0.36
0.70
2
49
A
TYR
0.57
0.80
0.51
2
50
A
GLY
0.59
0.41
0.56
2
51
A
GLY
0.64
0.41
0.58
1
53
A
ARG
0.42
0.51
0.60
9
54
A
LYS
0.52
0.25
0.60
9
55
A
ALA
0.44
0.38
0.61
9
56
A
MET
0.56
0.66
0.56
9
57
A
MET
0.98
0.66
0.17
10
58
A
THR
0.58
0.33
0.46
1
59
A
ASN
0.61
0.39
0.59
9
62
A
LYS
0.42
0.25
0.59
10
63
A
LYS
0.43
0.25
0.56
10
64
A
TYR
0.83
0.80
0.41
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.63
10
67
A
GLU
0.49
0.33
0.66
10
68
A
GLU
0.71
0.33
0.51
10
70
A
LYS
0.56
0.25
0.53
10
71
A
ALA
0.71
0.38
0.42
4
74
A
ASP
0.64
0.32
0.53
10
75
A
TYR
0.87
0.80
0.45
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
1
A
ALA
0.20
0.38
0.67
9
2
A
ASP
0.37
0.32
0.69
9
3
A
GLY
0.62
0.41
0.46
6
4
A
ALA
0.41
0.38
0.59
5
5
A
ALA
0.37
0.38
0.62
1
6
A
LEU
0.50
0.70
0.46
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.52
10
10
A
CYS
0.98
0.64
0.29
10
11
A
ILE
0.51
0.64
0.51
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.26
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.70
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.62
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.66
4
25
A
SER
0.40
0.36
0.69
6
27
A
LYS
0.72
0.25
0.50
3
28
A
PRO
0.65
0.47
0.54
10
30
A
LYS
0.68
0.25
0.57
10
31
A
GLY
0.84
0.41
0.54
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.54
10
34
A
ALA
0.57
0.38
0.49
10
35
A
GLU
0.45
0.33
0.65
10
36
A
GLU
0.82
0.33
0.51
9
38
A
TYR
0.35
0.80
0.44
9
43
A
GLY
0.64
0.41
0.46
1
44
A
TYR
0.79
0.80
0.29
8
46
A
ASP
0.48
0.32
0.66
1
47
A
GLY
0.73
0.41
0.68
1
48
A
SER
0.47
0.36
0.72
1
49
A
TYR
0.57
0.80
0.53
4
50
A
GLY
0.59
0.41
0.62
1
53
A
ARG
0.42
0.51
0.61
8
55
A
ALA
0.44
0.38
0.59
8
56
A
MET
0.56
0.66
0.55
8
57
A
MET
0.98
0.66
0.18
10
59
A
ASN
0.61
0.39
0.61
9
60
A
ALA
0.58
0.38
0.39
9
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
10
64
A
TYR
0.83
0.80
0.42
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.69
10
68
A
GLU
0.71
0.33
0.53
9
70
A
LYS
0.56
0.25
0.55
3
71
A
ALA
0.71
0.38
0.44
3
74
A
ASP
0.64
0.32
0.54
9
75
A
TYR
0.87
0.80
0.46
9
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.66
9
79
A
LEU
0.60
0.70
0.50
10
2
A
ASP
0.37
0.32
0.69
2
3
A
GLY
0.62
0.41
0.56
9
4
A
ALA
0.41
0.38
0.56
9
5
A
ALA
0.37
0.38
0.60
1
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.51
10
10
A
CYS
0.98
0.64
0.29
10
11
A
ILE
0.51
0.64
0.51
10
12
A
GLY
0.57
0.41
0.61
10
13
A
CYS
0.99
0.64
0.52
10
14
A
HIS
1.00
0.60
0.27
10
15
A
GLY
0.87
0.41
0.54
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.63
10
19
A
SER
0.44
0.36
0.63
10
20
A
LYS
0.78
0.25
0.64
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.70
1
25
A
SER
0.40
0.36
0.69
8
27
A
LYS
0.72
0.25
0.54
8
28
A
PRO
0.65
0.47
0.56
10
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.53
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.47
9
35
A
GLU
0.45
0.33
0.61
7
36
A
GLU
0.82
0.33
0.50
9
38
A
TYR
0.35
0.80
0.43
10
43
A
GLY
0.64
0.41
0.48
1
44
A
TYR
0.79
0.80
0.31
7
46
A
ASP
0.48
0.32
0.67
2
47
A
GLY
0.73
0.41
0.69
2
48
A
SER
0.47
0.36
0.71
2
49
A
TYR
0.57
0.80
0.52
9
50
A
GLY
0.59
0.41
0.57
1
51
A
GLY
0.64
0.41
0.60
1
53
A
ARG
0.42
0.51
0.62
6
55
A
ALA
0.44
0.38
0.61
6
56
A
MET
0.56
0.66
0.57
6
57
A
MET
0.98
0.66
0.19
8
59
A
ASN
0.61
0.39
0.60
7
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.59
10
64
A
TYR
0.83
0.80
0.44
10
65
A
SER
0.61
0.36
0.61
10
66
A
ASP
0.69
0.32
0.62
10
67
A
GLU
0.49
0.33
0.68
10
68
A
GLU
0.71
0.33
0.54
10
70
A
LYS
0.56
0.25
0.55
8
71
A
ALA
0.71
0.38
0.45
2
74
A
ASP
0.64
0.32
0.53
1
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.53
10
1
A
ALA
0.20
0.38
0.69
7
2
A
ASP
0.37
0.32
0.67
1
3
A
GLY
0.62
0.41
0.44
10
4
A
ALA
0.41
0.38
0.56
10
5
A
ALA
0.37
0.38
0.60
4
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.42
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.48
10
12
A
GLY
0.57
0.41
0.60
10
13
A
CYS
0.99
0.64
0.49
10
14
A
HIS
1.00
0.60
0.23
10
15
A
GLY
0.87
0.41
0.57
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.58
10
19
A
SER
0.44
0.36
0.59
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.60
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.67
2
25
A
SER
0.40
0.36
0.68
9
27
A
LYS
0.72
0.25
0.50
9
28
A
PRO
0.65
0.47
0.52
10
29
A
VAL
0.77
0.56
0.17
6
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.57
10
32
A
GLN
0.77
0.43
0.39
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.62
9
36
A
GLU
0.82
0.33
0.47
9
38
A
TYR
0.35
0.80
0.41
10
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.67
5
47
A
GLY
0.73
0.41
0.67
5
48
A
SER
0.47
0.36
0.72
5
49
A
TYR
0.57
0.80
0.52
9
50
A
GLY
0.59
0.41
0.57
5
51
A
GLY
0.64
0.41
0.58
4
53
A
ARG
0.42
0.51
0.60
10
54
A
LYS
0.52
0.25
0.61
8
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.53
10
57
A
MET
0.98
0.66
0.16
10
59
A
ASN
0.61
0.39
0.58
10
62
A
LYS
0.42
0.25
0.60
10
63
A
LYS
0.43
0.25
0.57
7
64
A
TYR
0.83
0.80
0.41
8
65
A
SER
0.61
0.36
0.59
8
66
A
ASP
0.69
0.32
0.64
8
67
A
GLU
0.49
0.33
0.65
8
68
A
GLU
0.71
0.33
0.51
8
70
A
LYS
0.56
0.25
0.53
8
71
A
ALA
0.71
0.38
0.41
1
74
A
ASP
0.64
0.32
0.52
9
75
A
TYR
0.87
0.80
0.41
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.66
10
79
A
LEU
0.60
0.70
0.54
10
4
A
ALA
0.41
0.38
0.52
6
5
A
ALA
0.37
0.38
0.60
6
6
A
LEU
0.50
0.70
0.42
10
8
A
LYS
0.44
0.25
0.60
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.22
10
11
A
ILE
0.51
0.64
0.47
10
12
A
GLY
0.57
0.41
0.58
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.21
10
15
A
GLY
0.87
0.41
0.58
10
16
A
ALA
0.56
0.38
0.64
10
17
A
ASP
0.52
0.32
0.54
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.66
10
24
A
GLY
0.52
0.41
0.62
7
25
A
SER
0.40
0.36
0.67
7
27
A
LYS
0.72
0.25
0.57
4
28
A
PRO
0.65
0.47
0.54
10
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.34
10
33
A
GLY
0.51
0.41
0.48
10
34
A
ALA
0.57
0.38
0.46
10
35
A
GLU
0.45
0.33
0.62
10
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.42
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.70
3
47
A
GLY
0.73
0.41
0.68
3
48
A
SER
0.47
0.36
0.72
3
49
A
TYR
0.57
0.80
0.50
3
50
A
GLY
0.59
0.41
0.55
3
51
A
GLY
0.64
0.41
0.57
2
52
A
GLU
0.60
0.33
0.67
4
53
A
ARG
0.42
0.51
0.57
10
54
A
LYS
0.52
0.25
0.59
10
55
A
ALA
0.44
0.38
0.59
10
56
A
MET
0.56
0.66
0.48
10
57
A
MET
0.98
0.66
0.13
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.57
5
74
A
ASP
0.64
0.32
0.52
6
75
A
TYR
0.87
0.80
0.45
10
76
A
MET
0.63
0.66
0.07
10
77
A
SER
0.59
0.36
0.50
10
78
A
LYS
0.49
0.25
0.65
10
79
A
LEU
0.60
0.70
0.50
10
1
A
ALA
0.20
0.38
0.69
8
3
A
GLY
0.62
0.41
0.47
5
4
A
ALA
0.41
0.38
0.57
5
6
A
LEU
0.50
0.70
0.45
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.48
10
10
A
CYS
0.98
0.64
0.25
10
11
A
ILE
0.51
0.64
0.50
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.48
10
14
A
HIS
1.00
0.60
0.25
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.67
10
19
A
SER
0.44
0.36
0.65
10
20
A
LYS
0.78
0.25
0.63
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.70
3
25
A
SER
0.40
0.36
0.70
9
27
A
LYS
0.72
0.25
0.53
8
28
A
PRO
0.65
0.47
0.54
10
29
A
VAL
0.77
0.56
0.21
2
30
A
LYS
0.68
0.25
0.58
10
31
A
GLY
0.84
0.41
0.58
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.50
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.63
9
36
A
GLU
0.82
0.33
0.52
10
38
A
TYR
0.35
0.80
0.41
10
43
A
GLY
0.64
0.41
0.48
3
44
A
TYR
0.79
0.80
0.28
6
46
A
ASP
0.48
0.32
0.68
3
47
A
GLY
0.73
0.41
0.69
3
48
A
SER
0.47
0.36
0.72
3
49
A
TYR
0.57
0.80
0.53
8
50
A
GLY
0.59
0.41
0.63
3
51
A
GLY
0.64
0.41
0.67
3
52
A
GLU
0.60
0.33
0.76
1
53
A
ARG
0.42
0.51
0.61
8
55
A
ALA
0.44
0.38
0.59
5
56
A
MET
0.56
0.66
0.54
7
57
A
MET
0.98
0.66
0.16
8
59
A
ASN
0.61
0.39
0.59
6
60
A
ALA
0.58
0.38
0.38
6
62
A
LYS
0.42
0.25
0.61
10
63
A
LYS
0.43
0.25
0.60
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.59
10
66
A
ASP
0.69
0.32
0.64
10
67
A
GLU
0.49
0.33
0.66
8
68
A
GLU
0.71
0.33
0.53
9
70
A
LYS
0.56
0.25
0.53
3
74
A
ASP
0.64
0.32
0.53
7
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.52
10
78
A
LYS
0.49
0.25
0.67
9
79
A
LEU
0.60
0.70
0.52
10
1
A
ALA
0.20
0.38
0.69
10
2
A
ASP
0.37
0.32
0.70
3
3
A
GLY
0.62
0.41
0.44
5
4
A
ALA
0.41
0.38
0.53
4
6
A
LEU
0.50
0.70
0.43
10
8
A
LYS
0.44
0.25
0.59
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.21
10
11
A
ILE
0.51
0.64
0.45
10
12
A
GLY
0.57
0.41
0.57
10
13
A
CYS
0.99
0.64
0.47
10
14
A
HIS
1.00
0.60
0.22
10
15
A
GLY
0.87
0.41
0.53
10
16
A
ALA
0.56
0.38
0.63
10
17
A
ASP
0.52
0.32
0.62
10
19
A
SER
0.44
0.36
0.62
10
20
A
LYS
0.78
0.25
0.62
10
21
A
ALA
0.43
0.38
0.61
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.69
1
25
A
SER
0.40
0.36
0.67
10
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.52
10
29
A
VAL
0.77
0.56
0.17
2
30
A
LYS
0.68
0.25
0.56
10
31
A
GLY
0.84
0.41
0.56
10
32
A
GLN
0.77
0.43
0.38
10
33
A
GLY
0.51
0.41
0.49
10
34
A
ALA
0.57
0.38
0.47
10
35
A
GLU
0.45
0.33
0.64
9
36
A
GLU
0.82
0.33
0.47
10
38
A
TYR
0.35
0.80
0.42
10
39
A
LYS
0.54
0.25
0.55
1
43
A
GLY
0.64
0.41
0.47
3
44
A
TYR
0.79
0.80
0.28
10
46
A
ASP
0.48
0.32
0.68
2
47
A
GLY
0.73
0.41
0.65
2
48
A
SER
0.47
0.36
0.70
2
49
A
TYR
0.57
0.80
0.51
10
50
A
GLY
0.59
0.41
0.57
2
51
A
GLY
0.64
0.41
0.59
2
53
A
ARG
0.42
0.51
0.59
10
55
A
ALA
0.44
0.38
0.60
10
56
A
MET
0.56
0.66
0.55
10
57
A
MET
0.98
0.66
0.15
10
59
A
ASN
0.61
0.39
0.57
10
62
A
LYS
0.42
0.25
0.59
10
63
A
LYS
0.43
0.25
0.57
10
64
A
TYR
0.83
0.80
0.40
10
65
A
SER
0.61
0.36
0.60
10
66
A
ASP
0.69
0.32
0.65
10
67
A
GLU
0.49
0.33
0.67
10
68
A
GLU
0.71
0.33
0.53
10
70
A
LYS
0.56
0.25
0.52
10
71
A
ALA
0.71
0.38
0.45
10
74
A
ASP
0.64
0.32
0.54
10
75
A
TYR
0.87
0.80
0.46
10
77
A
SER
0.59
0.36
0.51
10
78
A
LYS
0.49
0.25
0.67
10
79
A
LEU
0.60
0.70
0.49
10
2
A
ASP
0.37
0.32
0.63
3
3
A
GLY
0.62
0.41
0.55
5
4
A
ALA
0.41
0.38
0.55
5
6
A
LEU
0.50
0.70
0.44
10
8
A
LYS
0.44
0.25
0.61
10
9
A
SER
0.52
0.36
0.45
10
10
A
CYS
0.98
0.64
0.24
10
11
A
ILE
0.51
0.64
0.49
10
12
A
GLY
0.57
0.41
0.59
10
13
A
CYS
0.99
0.64
0.50
10
14
A
HIS
1.00
0.60
0.26
10
16
A
ALA
0.56
0.38
0.66
10
17
A
ASP
0.52
0.32
0.66
10
19
A
SER
0.44
0.36
0.64
10
20
A
LYS
0.78
0.25
0.65
10
21
A
ALA
0.43
0.38
0.63
10
23
A
MET
0.53
0.66
0.67
10
24
A
GLY
0.52
0.41
0.67
2
25
A
SER
0.40
0.36
0.69
10
27
A
LYS
0.72
0.25
0.52
10
28
A
PRO
0.65
0.47
0.55
10
29
A
VAL
0.77
0.56
0.22
3
30
A
LYS
0.68
0.25
0.59
10
31
A
GLY
0.84
0.41
0.59
10
32
A
GLN
0.77
0.43
0.40
10
33
A
GLY
0.51
0.41
0.51
10
34
A
ALA
0.57
0.38
0.50
10
35
A
GLU
0.45
0.33
0.63
10
36
A
GLU
0.82
0.33
0.49
10
38
A
TYR
0.35
0.80
0.45
10
44
A
TYR
0.79
0.80
0.27
4
49
A
TYR
0.57
0.80
0.52
10
53
A
ARG
0.42
0.51
0.61
4
55
A
ALA
0.44
0.38
0.59
4
56
A
MET
0.56
0.66
0.54
4
57
A
MET
0.98
0.66
0.16
4
59
A
ASN
0.61
0.39
0.59
4
62
A
LYS
0.42
0.25
0.60
5
63
A
LYS
0.43
0.25
0.59
2
64
A
TYR
0.83
0.80
0.43
3
65
A
SER
0.61
0.36
0.60
3
66
A
ASP
0.69
0.32
0.63
3
67
A
GLU
0.49
0.33
0.69
3
68
A
GLU
0.71
0.33
0.54
3
70
A
LYS
0.56
0.25
0.55
7
71
A
ALA
0.71
0.38
0.44
1
74
A
ASP
0.64
0.32
0.55
10
75
A
TYR
0.87
0.80
0.47
10
77
A
SER
0.59
0.36
0.53
10
78
A
LYS
0.49
0.25
0.68
10
79
A
LEU
0.60
0.70
0.53
10