Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1E0E chain B auto

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.33
1
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.55
10
28
B
ILE
0.10
0.64
0.29
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.60
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.48
10
35
B
GLN
0.97
0.43
0.42
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.21
7
38
B
ASN
0.82
0.39
0.48
3
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.34
4
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.42
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.58
10
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.34
10
29
B
PRO
1.00
0.47
0.60
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.40
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.22
7
38
B
ASN
0.82
0.39
0.47
5
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.38
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.48
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.49
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.28
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
6
39
B
SER
0.20
0.36
0.46
6
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.37
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.48
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.31
1
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
7
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.71
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.56
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.37
10
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.52
10
28
B
ILE
0.10
0.64
0.29
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.47
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.16
8
38
B
ASN
0.82
0.39
0.46
7
39
B
SER
0.20
0.36
0.46
8
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.70
10
1
B
PHE
1.00
1.00
0.66
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.35
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
17
B
SER
0.67
0.36
0.30
1
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.29
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.53
10
26
B
PHE
1.00
1.00
0.37
10
27
B
GLY
0.89
0.41
0.50
10
28
B
ILE
0.10
0.64
0.29
10
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.48
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
9
37
B
VAL
0.99
0.56
0.17
9
38
B
ASN
0.82
0.39
0.45
10
39
B
SER
0.20
0.36
0.47
10
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.58
9
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.49
10
18
B
ASN
1.00
0.39
0.41
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.52
10
28
B
ILE
0.10
0.64
0.30
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
6
38
B
ASN
0.82
0.39
0.47
5
39
B
SER
0.20
0.36
0.46
7
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.37
2
18
B
ASN
1.00
0.39
0.45
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.50
10
23
B
SER
0.41
0.36
0.44
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.58
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.23
6
38
B
ASN
0.82
0.39
0.48
5
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.59
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.34
5
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.21
7
38
B
ASN
0.82
0.39
0.48
6
39
B
SER
0.20
0.36
0.47
8
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.42
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.43
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.22
8
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.47
8
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.34
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.31
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.39
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.56
10
28
B
ILE
0.10
0.64
0.30
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.21
4
38
B
ASN
0.82
0.39
0.47
3
39
B
SER
0.20
0.36
0.47
3
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
1
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.44
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.59
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.22
8
38
B
ASN
0.82
0.39
0.49
9
39
B
SER
0.20
0.36
0.47
6
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.38
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.34
3
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.42
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.60
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.22
7
38
B
ASN
0.82
0.39
0.47
6
39
B
SER
0.20
0.36
0.47
5
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.58
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.56
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.31
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.31
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.59
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.22
5
38
B
ASN
0.82
0.39
0.48
3
39
B
SER
0.20
0.36
0.47
1
40
B
CYS
1.00
0.64
0.44
10
41
B
ALA
0.59
0.38
0.65
9
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.61
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.55
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.40
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.38
10
36
B
ILE
1.00
0.64
0.00
8
37
B
VAL
0.99
0.56
0.21
9
38
B
ASN
0.82
0.39
0.48
7
39
B
SER
0.20
0.36
0.48
5
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.66
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
3
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.43
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.43
10
27
B
GLY
0.89
0.41
0.56
10
28
B
ILE
0.10
0.64
0.30
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.46
10
37
B
VAL
0.99
0.56
0.23
4
38
B
ASN
0.82
0.39
0.48
3
39
B
SER
0.20
0.36
0.46
2
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
8
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.70
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.56
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.29
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.37
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.54
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
1
38
B
ASN
0.82
0.39
0.47
1
39
B
SER
0.20
0.36
0.46
2
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.58
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.65
10
16
B
HIS
1.00
0.60
0.52
10
17
B
SER
0.67
0.36
0.35
2
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.50
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.59
10
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.34
10
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.24
5
38
B
ASN
0.82
0.39
0.48
2
39
B
SER
0.20
0.36
0.47
5
40
B
CYS
1.00
0.64
0.44
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.67
10
43
B
CYS
1.00
0.64
0.51
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.34
2
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.58
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.43
10
37
B
VAL
0.99
0.56
0.23
4
38
B
ASN
0.82
0.39
0.48
6
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.31
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.33
1
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.38
10
27
B
GLY
0.89
0.41
0.58
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.23
8
38
B
ASN
0.82
0.39
0.50
8
39
B
SER
0.20
0.36
0.47
3
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.32
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
5
18
B
ASN
1.00
0.39
0.42
9
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.40
2
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.65
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.36
10
37
B
VAL
0.99
0.56
0.25
5
38
B
ASN
0.82
0.39
0.48
4
39
B
SER
0.20
0.36
0.46
10
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.35
2
18
B
ASN
1.00
0.39
0.45
10
19
B
VAL
0.69
0.56
0.35
10
20
B
LYS
0.62
0.25
0.66
10
21
B
GLU
0.89
0.33
0.50
10
23
B
SER
0.41
0.36
0.45
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.43
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.35
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.60
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.54
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.24
5
38
B
ASN
0.82
0.39
0.48
6
39
B
SER
0.20
0.36
0.44
3
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.63
9
43
B
CYS
1.00
0.64
0.51
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
18
B
ASN
1.00
0.39
0.38
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.58
10
21
B
GLU
0.89
0.33
0.45
10
23
B
SER
0.41
0.36
0.41
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.54
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.28
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.36
10
36
B
ILE
1.00
0.64
0.01
8
37
B
VAL
0.99
0.56
0.18
8
38
B
ASN
0.82
0.39
0.48
7
39
B
SER
0.20
0.36
0.48
10
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.32
3
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.61
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.44
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.57
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.20
4
38
B
ASN
0.82
0.39
0.48
2
39
B
SER
0.20
0.36
0.47
4
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.62
9
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.43
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.59
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.34
10
37
B
VAL
0.99
0.56
0.21
8
38
B
ASN
0.82
0.39
0.47
10
39
B
SER
0.20
0.36
0.47
9
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.53
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.42
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.65
10
16
B
HIS
1.00
0.60
0.53
10
17
B
SER
0.67
0.36
0.37
1
18
B
ASN
1.00
0.39
0.47
10
19
B
VAL
0.69
0.56
0.36
10
20
B
LYS
0.62
0.25
0.66
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.44
10
24
B
HIS
0.73
0.60
0.69
10
25
B
LYS
0.93
0.25
0.58
10
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.58
10
28
B
ILE
0.10
0.64
0.35
10
29
B
PRO
1.00
0.47
0.60
10
30
B
ASN
0.68
0.39
0.61
10
31
B
LEU
0.59
0.70
0.65
10
32
B
VAL
0.97
0.56
0.43
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.46
10
37
B
VAL
0.99
0.56
0.24
6
38
B
ASN
0.82
0.39
0.49
7
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.52
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.32
2
18
B
ASN
1.00
0.39
0.41
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.60
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.55
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.38
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.20
3
38
B
ASN
0.82
0.39
0.47
3
39
B
SER
0.20
0.36
0.47
5
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
9
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.37
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.62
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.34
2
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.28
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
6
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.59
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.51
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.63
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.48
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.27
10
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.37
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.36
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
8
39
B
SER
0.20
0.36
0.48
9
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.71
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.63
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.36
3
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.40
10
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.56
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.37
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.24
4
38
B
ASN
0.82
0.39
0.47
4
39
B
SER
0.20
0.36
0.45
5
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.62
8
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.71
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.36
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.26
10
10
B
GLU
0.97
0.33
0.49
10
11
B
GLU
0.85
0.33
0.36
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.62
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.48
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.29
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.38
10
24
B
HIS
0.73
0.60
0.65
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.38
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.25
10
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.54
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.18
10
38
B
ASN
0.82
0.39
0.46
6
39
B
SER
0.20
0.36
0.46
4
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.72
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.51
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.35
10
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.43
10
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.57
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.20
5
38
B
ASN
0.82
0.39
0.47
5
39
B
SER
0.20
0.36
0.46
4
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10