Pre-computed interfaces

How to use JET2 Viewer

References

Contact

JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1E0E chain B sc1

 

Download file

 

 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
7
21
B
GLU
0.89
0.33
0.47
3
23
B
SER
0.41
0.36
0.41
1
24
B
HIS
0.73
0.60
0.68
7
25
B
LYS
0.93
0.25
0.56
6
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.55
10
28
B
ILE
0.10
0.64
0.29
9
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.60
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.48
10
35
B
GLN
0.97
0.43
0.42
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.21
10
38
B
ASN
0.82
0.39
0.48
8
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.34
8
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
9
20
B
LYS
0.62
0.25
0.65
9
21
B
GLU
0.89
0.33
0.48
6
23
B
SER
0.41
0.36
0.42
4
24
B
HIS
0.73
0.60
0.68
9
25
B
LYS
0.93
0.25
0.58
7
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.34
9
29
B
PRO
1.00
0.47
0.60
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.40
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.22
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.45
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.62
9
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.38
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.48
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.49
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.32
9
20
B
LYS
0.62
0.25
0.62
9
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.41
4
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.28
9
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
6
39
B
SER
0.20
0.36
0.46
6
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.37
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.48
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.31
1
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.48
6
24
B
HIS
0.73
0.60
0.67
8
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.53
9
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
7
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.71
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.56
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.37
10
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.52
10
28
B
ILE
0.10
0.64
0.29
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.47
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.16
10
38
B
ASN
0.82
0.39
0.46
10
39
B
SER
0.20
0.36
0.46
10
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.70
10
1
B
PHE
1.00
1.00
0.66
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.35
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.29
7
20
B
LYS
0.62
0.25
0.63
4
21
B
GLU
0.89
0.33
0.47
5
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.53
3
26
B
PHE
1.00
1.00
0.37
10
27
B
GLY
0.89
0.41
0.50
10
28
B
ILE
0.10
0.64
0.29
10
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.48
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.17
10
38
B
ASN
0.82
0.39
0.45
5
39
B
SER
0.20
0.36
0.47
1
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
8
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.58
9
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.49
10
18
B
ASN
1.00
0.39
0.41
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.40
8
24
B
HIS
0.73
0.60
0.66
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.52
9
28
B
ILE
0.10
0.64
0.30
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
10
39
B
SER
0.20
0.36
0.46
10
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.37
5
18
B
ASN
1.00
0.39
0.45
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.50
9
23
B
SER
0.41
0.36
0.44
5
24
B
HIS
0.73
0.60
0.68
9
25
B
LYS
0.93
0.25
0.58
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.23
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.59
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.34
7
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
9
20
B
LYS
0.62
0.25
0.65
9
21
B
GLU
0.89
0.33
0.48
9
23
B
SER
0.41
0.36
0.40
6
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.21
10
38
B
ASN
0.82
0.39
0.48
10
39
B
SER
0.20
0.36
0.47
9
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.46
8
23
B
SER
0.41
0.36
0.42
7
24
B
HIS
0.73
0.60
0.67
9
25
B
LYS
0.93
0.25
0.57
9
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.53
9
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.43
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.22
10
38
B
ASN
0.82
0.39
0.48
10
39
B
SER
0.20
0.36
0.47
8
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.34
4
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.31
9
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
8
23
B
SER
0.41
0.36
0.39
3
24
B
HIS
0.73
0.60
0.68
7
25
B
LYS
0.93
0.25
0.56
7
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.56
9
28
B
ILE
0.10
0.64
0.30
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.21
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.47
7
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
1
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
2
23
B
SER
0.41
0.36
0.44
6
24
B
HIS
0.73
0.60
0.67
6
25
B
LYS
0.93
0.25
0.56
9
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.59
9
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.22
10
38
B
ASN
0.82
0.39
0.49
10
39
B
SER
0.20
0.36
0.47
7
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.38
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.34
4
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.63
9
21
B
GLU
0.89
0.33
0.47
1
23
B
SER
0.41
0.36
0.42
3
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
6
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.60
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.22
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.47
6
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.58
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.56
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.31
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.34
6
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.31
7
20
B
LYS
0.62
0.25
0.63
6
21
B
GLU
0.89
0.33
0.47
6
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
7
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.59
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.22
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.47
3
40
B
CYS
1.00
0.64
0.44
10
41
B
ALA
0.59
0.38
0.65
8
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.61
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.64
9
21
B
GLU
0.89
0.33
0.49
7
23
B
SER
0.41
0.36
0.41
6
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
7
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.55
10
28
B
ILE
0.10
0.64
0.31
9
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.40
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.38
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.21
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.48
7
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
9
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.66
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
8
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
7
20
B
LYS
0.62
0.25
0.64
6
21
B
GLU
0.89
0.33
0.49
2
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
3
26
B
PHE
1.00
1.00
0.43
10
27
B
GLY
0.89
0.41
0.56
10
28
B
ILE
0.10
0.64
0.30
6
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.46
10
37
B
VAL
0.99
0.56
0.23
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.46
3
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
8
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.70
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.56
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.29
10
20
B
LYS
0.62
0.25
0.62
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.37
6
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.54
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.36
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.46
10
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.58
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.52
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.65
10
16
B
HIS
1.00
0.60
0.52
10
17
B
SER
0.67
0.36
0.35
8
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
9
20
B
LYS
0.62
0.25
0.64
9
21
B
GLU
0.89
0.33
0.50
6
23
B
SER
0.41
0.36
0.41
4
24
B
HIS
0.73
0.60
0.68
9
25
B
LYS
0.93
0.25
0.59
8
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.53
10
28
B
ILE
0.10
0.64
0.34
9
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.59
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.24
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.47
5
40
B
CYS
1.00
0.64
0.44
10
41
B
ALA
0.59
0.38
0.64
9
42
B
GLN
0.59
0.43
0.67
10
43
B
CYS
1.00
0.64
0.51
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.34
2
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.48
10
23
B
SER
0.41
0.36
0.41
7
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.58
9
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.32
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.52
10
35
B
GLN
0.97
0.43
0.43
10
37
B
VAL
0.99
0.56
0.23
10
38
B
ASN
0.82
0.39
0.48
10
39
B
SER
0.20
0.36
0.45
6
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.41
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.31
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.40
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.68
9
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.33
2
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.48
4
23
B
SER
0.41
0.36
0.40
1
24
B
HIS
0.73
0.60
0.67
9
25
B
LYS
0.93
0.25
0.55
9
26
B
PHE
1.00
1.00
0.38
10
27
B
GLY
0.89
0.41
0.58
9
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.23
10
38
B
ASN
0.82
0.39
0.50
9
39
B
SER
0.20
0.36
0.47
5
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.75
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.69
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.32
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.33
8
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.32
9
20
B
LYS
0.62
0.25
0.65
9
21
B
GLU
0.89
0.33
0.48
9
23
B
SER
0.41
0.36
0.40
7
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.42
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.33
9
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
9
31
B
LEU
0.59
0.70
0.65
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.36
10
37
B
VAL
0.99
0.56
0.25
10
38
B
ASN
0.82
0.39
0.48
10
39
B
SER
0.20
0.36
0.46
9
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
9
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.65
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.54
10
11
B
GLU
0.85
0.33
0.41
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.64
10
16
B
HIS
1.00
0.60
0.51
10
17
B
SER
0.67
0.36
0.35
2
18
B
ASN
1.00
0.39
0.45
10
19
B
VAL
0.69
0.56
0.35
10
20
B
LYS
0.62
0.25
0.66
10
21
B
GLU
0.89
0.33
0.50
9
23
B
SER
0.41
0.36
0.45
8
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.57
9
26
B
PHE
1.00
1.00
0.43
10
27
B
GLY
0.89
0.41
0.60
10
28
B
ILE
0.10
0.64
0.35
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.60
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.54
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.24
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.44
3
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.51
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.30
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.61
10
16
B
HIS
1.00
0.60
0.47
10
18
B
ASN
1.00
0.39
0.38
10
19
B
VAL
0.69
0.56
0.30
10
20
B
LYS
0.62
0.25
0.58
9
21
B
GLU
0.89
0.33
0.45
10
23
B
SER
0.41
0.36
0.41
7
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.54
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
10
28
B
ILE
0.10
0.64
0.28
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.38
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.36
10
36
B
ILE
1.00
0.64
0.01
10
37
B
VAL
0.99
0.56
0.18
10
38
B
ASN
0.82
0.39
0.48
9
39
B
SER
0.20
0.36
0.48
8
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.51
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.67
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.32
5
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.61
9
21
B
GLU
0.89
0.33
0.47
6
23
B
SER
0.41
0.36
0.44
2
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
6
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.57
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.45
10
37
B
VAL
0.99
0.56
0.20
10
38
B
ASN
0.82
0.39
0.48
8
39
B
SER
0.20
0.36
0.47
4
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.62
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.63
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.50
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.68
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
18
B
ASN
1.00
0.39
0.43
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.64
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.43
5
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.56
9
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.59
9
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.59
10
30
B
ASN
0.68
0.39
0.57
10
31
B
LEU
0.59
0.70
0.63
10
32
B
VAL
0.97
0.56
0.39
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.34
10
37
B
VAL
0.99
0.56
0.21
10
38
B
ASN
0.82
0.39
0.47
10
39
B
SER
0.20
0.36
0.47
9
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.76
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.74
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.55
10
7
B
PRO
0.95
0.47
0.53
10
9
B
GLN
1.00
0.43
0.29
10
10
B
GLU
0.97
0.33
0.55
10
11
B
GLU
0.85
0.33
0.42
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.66
10
15
B
TYR
1.00
0.80
0.65
10
16
B
HIS
1.00
0.60
0.53
10
17
B
SER
0.67
0.36
0.37
2
18
B
ASN
1.00
0.39
0.47
10
19
B
VAL
0.69
0.56
0.36
10
20
B
LYS
0.62
0.25
0.66
10
21
B
GLU
0.89
0.33
0.48
1
23
B
SER
0.41
0.36
0.44
4
24
B
HIS
0.73
0.60
0.69
9
25
B
LYS
0.93
0.25
0.58
6
26
B
PHE
1.00
1.00
0.44
10
27
B
GLY
0.89
0.41
0.58
10
28
B
ILE
0.10
0.64
0.35
10
29
B
PRO
1.00
0.47
0.60
10
30
B
ASN
0.68
0.39
0.61
10
31
B
LEU
0.59
0.70
0.65
10
32
B
VAL
0.97
0.56
0.43
10
34
B
ARG
0.54
0.51
0.53
10
35
B
GLN
0.97
0.43
0.46
10
37
B
VAL
0.99
0.56
0.24
10
38
B
ASN
0.82
0.39
0.49
10
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.43
10
41
B
ALA
0.59
0.38
0.63
8
42
B
GLN
0.59
0.43
0.66
10
43
B
CYS
1.00
0.64
0.52
10
44
B
GLN
0.85
0.43
0.61
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.77
10
1
B
PHE
1.00
1.00
0.70
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.62
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.52
10
11
B
GLU
0.85
0.33
0.39
10
13
B
GLU
0.95
0.33
0.52
10
14
B
LYS
0.82
0.25
0.64
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.49
10
18
B
ASN
1.00
0.39
0.41
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.60
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.40
9
24
B
HIS
0.73
0.60
0.68
7
25
B
LYS
0.93
0.25
0.57
10
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.55
9
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.58
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.64
10
32
B
VAL
0.97
0.56
0.41
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.38
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.20
10
38
B
ASN
0.82
0.39
0.47
10
39
B
SER
0.20
0.36
0.47
9
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.64
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.73
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.61
10
5
B
ILE
1.00
0.64
0.37
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.38
9
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.62
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.49
10
17
B
SER
0.67
0.36
0.34
2
18
B
ASN
1.00
0.39
0.42
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.48
3
23
B
SER
0.41
0.36
0.40
1
24
B
HIS
0.73
0.60
0.67
7
25
B
LYS
0.93
0.25
0.56
6
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.54
9
28
B
ILE
0.10
0.64
0.28
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
6
39
B
SER
0.20
0.36
0.46
1
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.49
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.72
10
4
B
LYS
0.67
0.25
0.59
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.51
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.49
10
14
B
LYS
0.82
0.25
0.63
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.48
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.32
10
20
B
LYS
0.62
0.25
0.63
10
21
B
GLU
0.89
0.33
0.47
10
23
B
SER
0.41
0.36
0.40
8
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.56
10
26
B
PHE
1.00
1.00
0.39
10
27
B
GLY
0.89
0.41
0.53
9
28
B
ILE
0.10
0.64
0.27
10
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.56
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.37
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.36
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.19
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.48
9
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.63
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.75
10
46
B
LYS
1.00
0.25
0.71
10
1
B
PHE
1.00
1.00
0.69
10
2
B
LEU
0.83
0.70
0.68
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.40
10
6
B
GLU
0.87
0.33
0.53
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.28
10
10
B
GLU
0.97
0.33
0.53
10
11
B
GLU
0.85
0.33
0.38
10
13
B
GLU
0.95
0.33
0.51
10
14
B
LYS
0.82
0.25
0.63
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.36
8
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.34
10
20
B
LYS
0.62
0.25
0.65
9
21
B
GLU
0.89
0.33
0.49
9
23
B
SER
0.41
0.36
0.40
5
24
B
HIS
0.73
0.60
0.67
10
25
B
LYS
0.93
0.25
0.57
8
26
B
PHE
1.00
1.00
0.40
10
27
B
GLY
0.89
0.41
0.56
10
28
B
ILE
0.10
0.64
0.31
10
29
B
PRO
1.00
0.47
0.57
10
30
B
ASN
0.68
0.39
0.58
10
31
B
LEU
0.59
0.70
0.62
10
32
B
VAL
0.97
0.56
0.37
10
34
B
ARG
0.54
0.51
0.51
10
35
B
GLN
0.97
0.43
0.44
10
37
B
VAL
0.99
0.56
0.24
10
38
B
ASN
0.82
0.39
0.47
10
39
B
SER
0.20
0.36
0.45
6
40
B
CYS
1.00
0.64
0.42
10
41
B
ALA
0.59
0.38
0.62
9
42
B
GLN
0.59
0.43
0.65
10
43
B
CYS
1.00
0.64
0.50
10
44
B
GLN
0.85
0.43
0.60
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10
1
B
PHE
1.00
1.00
0.67
10
2
B
LEU
0.83
0.70
0.67
10
3
B
GLU
0.88
0.33
0.71
10
4
B
LYS
0.67
0.25
0.62
10
5
B
ILE
1.00
0.64
0.36
10
6
B
GLU
0.87
0.33
0.52
10
7
B
PRO
0.95
0.47
0.47
10
9
B
GLN
1.00
0.43
0.26
10
10
B
GLU
0.97
0.33
0.49
10
11
B
GLU
0.85
0.33
0.36
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.62
10
15
B
TYR
1.00
0.80
0.62
10
16
B
HIS
1.00
0.60
0.48
10
18
B
ASN
1.00
0.39
0.40
10
19
B
VAL
0.69
0.56
0.29
9
20
B
LYS
0.62
0.25
0.62
9
21
B
GLU
0.89
0.33
0.46
10
23
B
SER
0.41
0.36
0.38
3
24
B
HIS
0.73
0.60
0.65
10
25
B
LYS
0.93
0.25
0.55
8
26
B
PHE
1.00
1.00
0.38
10
27
B
GLY
0.89
0.41
0.53
9
28
B
ILE
0.10
0.64
0.25
9
29
B
PRO
1.00
0.47
0.55
10
30
B
ASN
0.68
0.39
0.54
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.49
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.18
10
38
B
ASN
0.82
0.39
0.46
6
39
B
SER
0.20
0.36
0.46
4
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
9
42
B
GLN
0.59
0.43
0.63
10
43
B
CYS
1.00
0.64
0.47
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.73
10
46
B
LYS
1.00
0.25
0.72
10
1
B
PHE
1.00
1.00
0.68
10
2
B
LEU
0.83
0.70
0.66
10
3
B
GLU
0.88
0.33
0.73
10
4
B
LYS
0.67
0.25
0.64
10
5
B
ILE
1.00
0.64
0.39
10
6
B
GLU
0.87
0.33
0.54
10
7
B
PRO
0.95
0.47
0.49
10
9
B
GLN
1.00
0.43
0.27
10
10
B
GLU
0.97
0.33
0.51
10
11
B
GLU
0.85
0.33
0.37
10
13
B
GLU
0.95
0.33
0.50
10
14
B
LYS
0.82
0.25
0.65
10
15
B
TYR
1.00
0.80
0.63
10
16
B
HIS
1.00
0.60
0.50
10
17
B
SER
0.67
0.36
0.35
6
18
B
ASN
1.00
0.39
0.44
10
19
B
VAL
0.69
0.56
0.33
10
20
B
LYS
0.62
0.25
0.65
10
21
B
GLU
0.89
0.33
0.49
10
23
B
SER
0.41
0.36
0.43
8
24
B
HIS
0.73
0.60
0.68
10
25
B
LYS
0.93
0.25
0.55
10
26
B
PHE
1.00
1.00
0.41
10
27
B
GLY
0.89
0.41
0.57
9
28
B
ILE
0.10
0.64
0.33
10
29
B
PRO
1.00
0.47
0.56
10
30
B
ASN
0.68
0.39
0.55
10
31
B
LEU
0.59
0.70
0.61
10
32
B
VAL
0.97
0.56
0.35
10
34
B
ARG
0.54
0.51
0.50
10
35
B
GLN
0.97
0.43
0.44
10
36
B
ILE
1.00
0.64
0.00
10
37
B
VAL
0.99
0.56
0.20
10
38
B
ASN
0.82
0.39
0.47
9
39
B
SER
0.20
0.36
0.46
7
40
B
CYS
1.00
0.64
0.41
10
41
B
ALA
0.59
0.38
0.62
10
42
B
GLN
0.59
0.43
0.64
10
43
B
CYS
1.00
0.64
0.48
10
44
B
GLN
0.85
0.43
0.59
10
45
B
GLN
0.81
0.43
0.74
10
46
B
LYS
1.00
0.25
0.74
10