Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1F3Y chain A sc1

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
GLY
0.07
0.41
0.54
6
2
A
PRO
0.07
0.47
0.56
6
3
A
LEU
0.13
0.70
0.36
6
6
A
MET
0.21
0.66
0.51
6
7
A
ASP
0.18
0.32
0.61
6
8
A
SER
0.20
0.36
0.62
6
10
A
PRO
0.47
0.47
0.51
6
11
A
GLU
0.24
0.33
0.63
6
13
A
TYR
0.75
0.80
0.33
10
14
A
ARG
0.83
0.51
0.33
6
16
A
ASN
0.77
0.39
0.20
5
24
A
ASN
0.30
0.39
0.66
6
33
A
ARG
0.88
0.51
0.42
6
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.57
6
37
A
PRO
0.45
0.47
0.67
6
38
A
ASP
0.43
0.32
0.63
6
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.21
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.39
6
49
A
GLU
0.45
0.33
0.67
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.60
10
56
A
ALA
0.90
0.38
0.38
5
59
A
ARG
1.00
0.51
0.54
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.32
10
66
A
GLY
0.85
0.41
0.43
2
72
A
VAL
0.58
0.56
0.49
6
73
A
ILE
0.51
0.64
0.52
6
77
A
PRO
0.67
0.47
0.54
6
78
A
TYR
0.39
0.80
0.48
6
79
A
TRP
0.84
0.99
0.34
10
82
A
TYR
0.95
0.80
0.24
6
84
A
PHE
0.83
1.00
0.32
10
85
A
PRO
0.94
0.47
0.52
6
86
A
PRO
0.43
0.47
0.66
6
87
A
LYS
0.46
0.25
0.72
6
88
A
VAL
0.61
0.56
0.48
6
92
A
LEU
0.45
0.70
0.38
10
94
A
ILE
0.34
0.64
0.62
6
95
A
GLN
0.40
0.43
0.58
6
96
A
TRP
0.71
0.99
0.48
10
97
A
GLY
0.50
0.41
0.68
6
98
A
SER
0.59
0.36
0.71
6
99
A
ASP
0.48
0.32
0.63
6
100
A
TRP
0.64
0.99
0.46
10
102
A
GLY
0.94
0.41
0.23
9
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.07
10
108
A
PHE
0.82
1.00
0.26
6
112
A
PHE
0.75
1.00
0.45
6
114
A
GLY
0.76
0.41
0.63
6
115
A
GLN
0.33
0.43
0.69
6
117
A
GLN
0.39
0.43
0.71
6
119
A
ILE
0.71
0.64
0.42
6
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.58
10
130
A
GLU
0.98
0.33
0.38
10
131
A
PHE
0.96
1.00
0.31
10
134
A
TRP
0.86
0.99
0.43
10
136
A
TRP
0.90
0.99
0.45
6
137
A
VAL
0.44
0.56
0.44
6
145
A
LEU
0.56
0.70
0.54
6
147
A
VAL
0.66
0.56
0.38
5
149
A
PHE
0.83
1.00
0.37
6
153
A
VAL
0.73
0.56
0.19
5
158
A
LEU
0.57
0.70
0.37
5
2
A
PRO
0.07
0.47
0.53
3
3
A
LEU
0.13
0.70
0.38
3
6
A
MET
0.21
0.66
0.50
3
9
A
PRO
0.46
0.47
0.51
3
11
A
GLU
0.24
0.33
0.62
3
13
A
TYR
0.75
0.80
0.31
10
14
A
ARG
0.83
0.51
0.29
4
24
A
ASN
0.30
0.39
0.65
3
33
A
ARG
0.88
0.51
0.38
6
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.61
6
36
A
ILE
0.48
0.64
0.59
6
37
A
PRO
0.45
0.47
0.65
6
38
A
ASP
0.43
0.32
0.63
3
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.21
6
44
A
GLN
0.94
0.43
0.05
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.29
10
47
A
ILE
0.68
0.64
0.36
3
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.70
10
51
A
GLU
1.00
0.33
0.56
10
54
A
ARG
0.43
0.51
0.48
10
59
A
ARG
1.00
0.51
0.52
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
3
73
A
ILE
0.51
0.64
0.51
3
78
A
TYR
0.39
0.80
0.48
10
82
A
TYR
0.95
0.80
0.26
10
84
A
PHE
0.83
1.00
0.33
10
85
A
PRO
0.94
0.47
0.46
3
86
A
PRO
0.43
0.47
0.64
3
87
A
LYS
0.46
0.25
0.75
3
88
A
VAL
0.61
0.56
0.52
3
89
A
ARG
0.47
0.51
0.49
3
90
A
GLU
0.45
0.33
0.65
2
91
A
LYS
0.56
0.25
0.69
3
92
A
LEU
0.45
0.70
0.46
3
94
A
ILE
0.34
0.64
0.55
3
95
A
GLN
0.40
0.43
0.62
3
96
A
TRP
0.71
0.99
0.44
10
97
A
GLY
0.50
0.41
0.69
3
98
A
SER
0.59
0.36
0.68
3
99
A
ASP
0.48
0.32
0.61
3
100
A
TRP
0.64
0.99
0.41
10
103
A
GLN
0.95
0.43
0.15
10
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.44
3
114
A
GLY
0.76
0.41
0.62
3
115
A
GLN
0.33
0.43
0.68
3
117
A
GLN
0.39
0.43
0.71
3
119
A
ILE
0.71
0.64
0.41
3
120
A
ASN
0.62
0.39
0.56
3
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.58
10
130
A
GLU
0.98
0.33
0.40
10
132
A
GLY
0.68
0.41
0.49
2
134
A
TRP
0.86
0.99
0.42
3
136
A
TRP
0.90
0.99
0.40
3
145
A
LEU
0.56
0.70
0.53
3
147
A
VAL
0.66
0.56
0.38
3
149
A
PHE
0.83
1.00
0.34
10
150
A
LYS
0.85
0.25
0.20
10
3
A
LEU
0.13
0.70
0.35
10
6
A
MET
0.21
0.66
0.48
10
7
A
ASP
0.18
0.32
0.61
10
8
A
SER
0.20
0.36
0.61
10
9
A
PRO
0.46
0.47
0.49
10
10
A
PRO
0.47
0.47
0.47
10
11
A
GLU
0.24
0.33
0.60
10
13
A
TYR
0.75
0.80
0.34
10
14
A
ARG
0.83
0.51
0.31
10
16
A
ASN
0.77
0.39
0.19
10
24
A
ASN
0.30
0.39
0.65
10
33
A
ARG
0.88
0.51
0.45
10
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.60
10
37
A
PRO
0.45
0.47
0.67
10
38
A
ASP
0.43
0.32
0.64
10
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.24
10
44
A
GLN
0.94
0.43
0.11
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.37
10
49
A
GLU
0.45
0.33
0.67
10
50
A
GLY
0.74
0.41
0.69
10
51
A
GLU
1.00
0.33
0.61
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.45
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.44
10
73
A
ILE
0.51
0.64
0.53
10
77
A
PRO
0.67
0.47
0.53
10
78
A
TYR
0.39
0.80
0.48
10
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.19
10
83
A
ASP
0.84
0.32
0.35
7
84
A
PHE
0.83
1.00
0.36
10
85
A
PRO
0.94
0.47
0.57
10
86
A
PRO
0.43
0.47
0.71
10
87
A
LYS
0.46
0.25
0.77
10
88
A
VAL
0.61
0.56
0.54
10
89
A
ARG
0.47
0.51
0.47
10
92
A
LEU
0.45
0.70
0.42
10
94
A
ILE
0.34
0.64
0.54
10
95
A
GLN
0.40
0.43
0.61
10
96
A
TRP
0.71
0.99
0.39
10
97
A
GLY
0.50
0.41
0.63
10
98
A
SER
0.59
0.36
0.67
10
99
A
ASP
0.48
0.32
0.60
10
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.16
10
105
A
GLN
0.95
0.43
0.07
10
112
A
PHE
0.75
1.00
0.45
10
114
A
GLY
0.76
0.41
0.63
10
115
A
GLN
0.33
0.43
0.69
10
117
A
GLN
0.39
0.43
0.71
10
119
A
ILE
0.71
0.64
0.42
10
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.57
10
130
A
GLU
0.98
0.33
0.39
10
131
A
PHE
0.96
1.00
0.31
10
134
A
TRP
0.86
0.99
0.43
10
136
A
TRP
0.90
0.99
0.43
10
145
A
LEU
0.56
0.70
0.53
10
147
A
VAL
0.66
0.56
0.40
10
149
A
PHE
0.83
1.00
0.38
10
150
A
LYS
0.85
0.25
0.24
1
153
A
VAL
0.73
0.56
0.19
10
2
A
PRO
0.07
0.47
0.52
9
3
A
LEU
0.13
0.70
0.33
9
6
A
MET
0.21
0.66
0.50
9
9
A
PRO
0.46
0.47
0.49
9
13
A
TYR
0.75
0.80
0.30
10
14
A
ARG
0.83
0.51
0.29
9
16
A
ASN
0.77
0.39
0.19
9
33
A
ARG
0.88
0.51
0.41
9
34
A
LEU
0.46
0.70
0.54
10
36
A
ILE
0.48
0.64
0.58
9
37
A
PRO
0.45
0.47
0.66
9
38
A
ASP
0.43
0.32
0.63
9
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.21
10
44
A
GLN
0.94
0.43
0.09
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.37
9
49
A
GLU
0.45
0.33
0.67
10
50
A
GLY
0.74
0.41
0.69
10
51
A
GLU
1.00
0.33
0.60
10
54
A
ARG
0.43
0.51
0.47
10
58
A
ILE
0.43
0.64
0.42
10
59
A
ARG
1.00
0.51
0.49
10
60
A
GLU
1.00
0.33
0.30
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.43
7
72
A
VAL
0.58
0.56
0.48
9
82
A
TYR
0.95
0.80
0.26
10
84
A
PHE
0.83
1.00
0.34
10
85
A
PRO
0.94
0.47
0.54
9
86
A
PRO
0.43
0.47
0.67
9
87
A
LYS
0.46
0.25
0.76
9
88
A
VAL
0.61
0.56
0.51
9
89
A
ARG
0.47
0.51
0.53
9
90
A
GLU
0.45
0.33
0.66
9
92
A
LEU
0.45
0.70
0.36
10
94
A
ILE
0.34
0.64
0.63
9
95
A
GLN
0.40
0.43
0.56
9
96
A
TRP
0.71
0.99
0.42
10
97
A
GLY
0.50
0.41
0.67
9
98
A
SER
0.59
0.36
0.63
9
99
A
ASP
0.48
0.32
0.56
9
100
A
TRP
0.64
0.99
0.39
10
102
A
GLY
0.94
0.41
0.21
10
103
A
GLN
0.95
0.43
0.14
10
105
A
GLN
0.95
0.43
0.07
10
108
A
PHE
0.82
1.00
0.26
9
112
A
PHE
0.75
1.00
0.44
9
114
A
GLY
0.76
0.41
0.62
9
115
A
GLN
0.33
0.43
0.70
9
116
A
ASP
0.58
0.32
0.57
9
117
A
GLN
0.39
0.43
0.70
9
119
A
ILE
0.71
0.64
0.41
9
121
A
LEU
0.71
0.70
0.41
10
122
A
LEU
0.32
0.70
0.58
10
123
A
GLY
0.47
0.41
0.62
9
130
A
GLU
0.98
0.33
0.39
10
131
A
PHE
0.96
1.00
0.30
10
134
A
TRP
0.86
0.99
0.42
10
135
A
SER
0.51
0.36
0.45
9
136
A
TRP
0.90
0.99
0.44
9
145
A
LEU
0.56
0.70
0.53
9
147
A
VAL
0.66
0.56
0.38
9
149
A
PHE
0.83
1.00
0.37
9
150
A
LYS
0.85
0.25
0.21
9
2
A
PRO
0.07
0.47
0.47
10
6
A
MET
0.21
0.66
0.52
10
7
A
ASP
0.18
0.32
0.61
10
8
A
SER
0.20
0.36
0.63
10
10
A
PRO
0.47
0.47
0.54
10
11
A
GLU
0.24
0.33
0.62
10
13
A
TYR
0.75
0.80
0.35
10
14
A
ARG
0.83
0.51
0.35
10
15
A
ARG
0.62
0.51
0.35
1
16
A
ASN
0.77
0.39
0.16
10
33
A
ARG
0.88
0.51
0.39
10
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.60
10
36
A
ILE
0.48
0.64
0.55
10
37
A
PRO
0.45
0.47
0.67
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.40
10
41
A
GLN
0.92
0.43
0.20
10
44
A
GLN
0.94
0.43
0.05
10
45
A
GLY
1.00
0.41
0.18
10
46
A
GLY
0.95
0.41
0.28
10
47
A
ILE
0.68
0.64
0.37
10
48
A
ASP
0.81
0.32
0.52
6
49
A
GLU
0.45
0.33
0.64
10
50
A
GLY
0.74
0.41
0.67
10
51
A
GLU
1.00
0.33
0.58
10
58
A
ILE
0.43
0.64
0.41
10
59
A
ARG
1.00
0.51
0.52
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
10
77
A
PRO
0.67
0.47
0.54
10
78
A
TYR
0.39
0.80
0.49
10
79
A
TRP
0.84
0.99
0.33
10
84
A
PHE
0.83
1.00
0.36
10
85
A
PRO
0.94
0.47
0.59
10
86
A
PRO
0.43
0.47
0.71
10
87
A
LYS
0.46
0.25
0.73
4
88
A
VAL
0.61
0.56
0.50
10
89
A
ARG
0.47
0.51
0.54
10
92
A
LEU
0.45
0.70
0.34
10
94
A
ILE
0.34
0.64
0.63
10
95
A
GLN
0.40
0.43
0.52
10
96
A
TRP
0.71
0.99
0.41
10
97
A
GLY
0.50
0.41
0.61
10
98
A
SER
0.59
0.36
0.69
10
99
A
ASP
0.48
0.32
0.63
10
100
A
TRP
0.64
0.99
0.47
10
103
A
GLN
0.95
0.43
0.16
10
115
A
GLN
0.33
0.43
0.68
10
117
A
GLN
0.39
0.43
0.71
10
119
A
ILE
0.71
0.64
0.40
10
121
A
LEU
0.71
0.70
0.42
10
122
A
LEU
0.32
0.70
0.60
10
123
A
GLY
0.47
0.41
0.60
10
125
A
GLY
0.40
0.41
0.61
10
130
A
GLU
0.98
0.33
0.37
10
132
A
GLY
0.68
0.41
0.50
7
134
A
TRP
0.86
0.99
0.41
10
135
A
SER
0.51
0.36
0.43
10
136
A
TRP
0.90
0.99
0.43
10
137
A
VAL
0.44
0.56
0.42
10
141
A
GLN
0.35
0.43
0.58
7
145
A
LEU
0.56
0.70
0.53
10
147
A
VAL
0.66
0.56
0.35
10
149
A
PHE
0.83
1.00
0.30
10
150
A
LYS
0.85
0.25
0.17
10
3
A
LEU
0.13
0.70
0.34
10
4
A
GLY
0.10
0.41
0.47
10
6
A
MET
0.21
0.66
0.50
10
7
A
ASP
0.18
0.32
0.59
10
8
A
SER
0.20
0.36
0.61
10
9
A
PRO
0.46
0.47
0.49
10
11
A
GLU
0.24
0.33
0.61
10
13
A
TYR
0.75
0.80
0.31
10
14
A
ARG
0.83
0.51
0.28
10
24
A
ASN
0.30
0.39
0.66
10
33
A
ARG
0.88
0.51
0.42
10
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.58
10
37
A
PRO
0.45
0.47
0.64
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.06
10
45
A
GLY
1.00
0.41
0.17
10
46
A
GLY
0.95
0.41
0.28
10
47
A
ILE
0.68
0.64
0.35
10
49
A
GLU
0.45
0.33
0.64
10
50
A
GLY
0.74
0.41
0.67
10
51
A
GLU
1.00
0.33
0.60
10
58
A
ILE
0.43
0.64
0.44
10
59
A
ARG
1.00
0.51
0.47
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.42
9
73
A
ILE
0.51
0.64
0.51
10
77
A
PRO
0.67
0.47
0.55
10
78
A
TYR
0.39
0.80
0.49
10
79
A
TRP
0.84
0.99
0.32
10
82
A
TYR
0.95
0.80
0.16
10
83
A
ASP
0.84
0.32
0.33
2
84
A
PHE
0.83
1.00
0.35
10
85
A
PRO
0.94
0.47
0.52
10
86
A
PRO
0.43
0.47
0.67
10
87
A
LYS
0.46
0.25
0.76
10
88
A
VAL
0.61
0.56
0.53
10
89
A
ARG
0.47
0.51
0.50
10
92
A
LEU
0.45
0.70
0.37
10
94
A
ILE
0.34
0.64
0.59
10
95
A
GLN
0.40
0.43
0.56
10
96
A
TRP
0.71
0.99
0.40
10
97
A
GLY
0.50
0.41
0.65
10
98
A
SER
0.59
0.36
0.66
10
99
A
ASP
0.48
0.32
0.60
10
100
A
TRP
0.64
0.99
0.42
10
103
A
GLN
0.95
0.43
0.17
10
112
A
PHE
0.75
1.00
0.44
10
115
A
GLN
0.33
0.43
0.68
10
116
A
ASP
0.58
0.32
0.58
10
117
A
GLN
0.39
0.43
0.71
10
119
A
ILE
0.71
0.64
0.40
10
120
A
ASN
0.62
0.39
0.56
10
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.57
10
130
A
GLU
0.98
0.33
0.38
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
1
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
10
145
A
LEU
0.56
0.70
0.53
10
147
A
VAL
0.66
0.56
0.39
9
149
A
PHE
0.83
1.00
0.35
10
150
A
LYS
0.85
0.25
0.21
7
1
A
GLY
0.07
0.41
0.51
4
2
A
PRO
0.07
0.47
0.52
4
3
A
LEU
0.13
0.70
0.32
4
6
A
MET
0.21
0.66
0.48
4
8
A
SER
0.20
0.36
0.61
4
9
A
PRO
0.46
0.47
0.48
4
10
A
PRO
0.47
0.47
0.47
4
11
A
GLU
0.24
0.33
0.64
4
13
A
TYR
0.75
0.80
0.32
7
14
A
ARG
0.83
0.51
0.32
4
16
A
ASN
0.77
0.39
0.17
4
24
A
ASN
0.30
0.39
0.66
4
33
A
ARG
0.88
0.51
0.44
4
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.62
4
36
A
ILE
0.48
0.64
0.59
4
37
A
PRO
0.45
0.47
0.65
4
38
A
ASP
0.43
0.32
0.63
4
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.28
10
49
A
GLU
0.45
0.33
0.64
10
50
A
GLY
0.74
0.41
0.66
10
51
A
GLU
1.00
0.33
0.58
10
54
A
ARG
0.43
0.51
0.48
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.32
10
66
A
GLY
0.85
0.41
0.42
2
73
A
ILE
0.51
0.64
0.51
4
78
A
TYR
0.39
0.80
0.46
10
79
A
TRP
0.84
0.99
0.31
10
82
A
TYR
0.95
0.80
0.22
10
84
A
PHE
0.83
1.00
0.34
7
85
A
PRO
0.94
0.47
0.54
4
86
A
PRO
0.43
0.47
0.68
4
87
A
LYS
0.46
0.25
0.74
3
88
A
VAL
0.61
0.56
0.50
4
90
A
GLU
0.45
0.33
0.65
3
92
A
LEU
0.45
0.70
0.39
7
94
A
ILE
0.34
0.64
0.58
4
95
A
GLN
0.40
0.43
0.62
4
96
A
TRP
0.71
0.99
0.43
7
97
A
GLY
0.50
0.41
0.69
4
98
A
SER
0.59
0.36
0.68
4
99
A
ASP
0.48
0.32
0.63
4
100
A
TRP
0.64
0.99
0.44
7
103
A
GLN
0.95
0.43
0.17
7
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.45
4
115
A
GLN
0.33
0.43
0.69
4
117
A
GLN
0.39
0.43
0.70
4
119
A
ILE
0.71
0.64
0.41
4
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.56
10
130
A
GLU
0.98
0.33
0.37
10
131
A
PHE
0.96
1.00
0.30
10
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
4
145
A
LEU
0.56
0.70
0.55
4
147
A
VAL
0.66
0.56
0.41
3
149
A
PHE
0.83
1.00
0.36
10
3
A
LEU
0.13
0.70
0.32
6
6
A
MET
0.21
0.66
0.47
6
7
A
ASP
0.18
0.32
0.61
6
8
A
SER
0.20
0.36
0.63
6
9
A
PRO
0.46
0.47
0.52
6
10
A
PRO
0.47
0.47
0.45
6
13
A
TYR
0.75
0.80
0.30
10
14
A
ARG
0.83
0.51
0.33
6
16
A
ASN
0.77
0.39
0.20
6
33
A
ARG
0.88
0.51
0.42
10
34
A
LEU
0.46
0.70
0.54
10
35
A
ASP
0.70
0.32
0.63
7
36
A
ILE
0.48
0.64
0.58
7
37
A
PRO
0.45
0.47
0.66
7
38
A
ASP
0.43
0.32
0.63
6
40
A
TRP
0.98
0.99
0.41
9
44
A
GLN
0.94
0.43
0.08
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.37
6
48
A
ASP
0.81
0.32
0.53
10
49
A
GLU
0.45
0.33
0.67
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.59
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.43
6
77
A
PRO
0.67
0.47
0.53
6
78
A
TYR
0.39
0.80
0.47
10
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.21
10
84
A
PHE
0.83
1.00
0.40
6
85
A
PRO
0.94
0.47
0.55
6
86
A
PRO
0.43
0.47
0.68
6
87
A
LYS
0.46
0.25
0.71
6
88
A
VAL
0.61
0.56
0.55
6
90
A
GLU
0.45
0.33
0.65
1
91
A
LYS
0.56
0.25
0.71
1
92
A
LEU
0.45
0.70
0.42
6
94
A
ILE
0.34
0.64
0.60
6
95
A
GLN
0.40
0.43
0.64
6
96
A
TRP
0.71
0.99
0.42
10
97
A
GLY
0.50
0.41
0.69
6
98
A
SER
0.59
0.36
0.65
6
99
A
ASP
0.48
0.32
0.61
6
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.14
10
105
A
GLN
0.95
0.43
0.07
10
115
A
GLN
0.33
0.43
0.69
6
116
A
ASP
0.58
0.32
0.58
6
117
A
GLN
0.39
0.43
0.70
6
119
A
ILE
0.71
0.64
0.40
6
120
A
ASN
0.62
0.39
0.55
6
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.58
10
130
A
GLU
0.98
0.33
0.37
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
3
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
6
145
A
LEU
0.56
0.70
0.53
6
147
A
VAL
0.66
0.56
0.39
6
149
A
PHE
0.83
1.00
0.37
9
150
A
LYS
0.85
0.25
0.21
8
2
A
PRO
0.07
0.47
0.48
7
3
A
LEU
0.13
0.70
0.27
8
6
A
MET
0.21
0.66
0.49
8
9
A
PRO
0.46
0.47
0.48
8
10
A
PRO
0.47
0.47
0.48
8
11
A
GLU
0.24
0.33
0.64
8
13
A
TYR
0.75
0.80
0.34
8
14
A
ARG
0.83
0.51
0.31
7
15
A
ARG
0.62
0.51
0.38
3
16
A
ASN
0.77
0.39
0.17
8
24
A
ASN
0.30
0.39
0.65
9
33
A
ARG
0.88
0.51
0.42
9
34
A
LEU
0.46
0.70
0.52
10
35
A
ASP
0.70
0.32
0.63
9
36
A
ILE
0.48
0.64
0.57
9
37
A
PRO
0.45
0.47
0.64
9
38
A
ASP
0.43
0.32
0.62
9
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.36
9
49
A
GLU
0.45
0.33
0.64
10
50
A
GLY
0.74
0.41
0.69
10
51
A
GLU
1.00
0.33
0.59
10
56
A
ALA
0.90
0.38
0.39
9
58
A
ILE
0.43
0.64
0.42
10
59
A
ARG
1.00
0.51
0.54
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
7
73
A
ILE
0.51
0.64
0.51
9
82
A
TYR
0.95
0.80
0.16
8
84
A
PHE
0.83
1.00
0.41
7
85
A
PRO
0.94
0.47
0.59
7
86
A
PRO
0.43
0.47
0.71
7
87
A
LYS
0.46
0.25
0.75
7
88
A
VAL
0.61
0.56
0.52
7
92
A
LEU
0.45
0.70
0.32
8
94
A
ILE
0.34
0.64
0.62
6
95
A
GLN
0.40
0.43
0.54
6
96
A
TRP
0.71
0.99
0.48
8
97
A
GLY
0.50
0.41
0.68
6
98
A
SER
0.59
0.36
0.72
6
99
A
ASP
0.48
0.32
0.62
8
100
A
TRP
0.64
0.99
0.45
8
103
A
GLN
0.95
0.43
0.17
8
112
A
PHE
0.75
1.00
0.43
9
114
A
GLY
0.76
0.41
0.61
9
115
A
GLN
0.33
0.43
0.68
9
116
A
ASP
0.58
0.32
0.57
9
117
A
GLN
0.39
0.43
0.70
9
119
A
ILE
0.71
0.64
0.39
9
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.58
10
123
A
GLY
0.47
0.41
0.64
9
130
A
GLU
0.98
0.33
0.41
10
134
A
TRP
0.86
0.99
0.40
9
136
A
TRP
0.90
0.99
0.44
9
137
A
VAL
0.44
0.56
0.43
9
145
A
LEU
0.56
0.70
0.53
9
147
A
VAL
0.66
0.56
0.38
9
149
A
PHE
0.83
1.00
0.37
9
150
A
LYS
0.85
0.25
0.22
4
1
A
GLY
0.07
0.41
0.54
8
2
A
PRO
0.07
0.47
0.51
8
6
A
MET
0.21
0.66
0.49
8
7
A
ASP
0.18
0.32
0.61
8
8
A
SER
0.20
0.36
0.60
8
9
A
PRO
0.46
0.47
0.47
8
11
A
GLU
0.24
0.33
0.61
8
13
A
TYR
0.75
0.80
0.31
10
14
A
ARG
0.83
0.51
0.35
8
15
A
ARG
0.62
0.51
0.40
1
16
A
ASN
0.77
0.39
0.20
8
24
A
ASN
0.30
0.39
0.65
8
33
A
ARG
0.88
0.51
0.37
8
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.60
8
37
A
PRO
0.45
0.47
0.65
8
38
A
ASP
0.43
0.32
0.63
8
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.19
10
44
A
GLN
0.94
0.43
0.08
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.38
8
49
A
GLU
0.45
0.33
0.67
9
50
A
GLY
0.74
0.41
0.68
9
51
A
GLU
1.00
0.33
0.60
9
54
A
ARG
0.43
0.51
0.49
10
59
A
ARG
1.00
0.51
0.55
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.31
10
73
A
ILE
0.51
0.64
0.52
8
77
A
PRO
0.67
0.47
0.55
8
78
A
TYR
0.39
0.80
0.48
8
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.23
10
84
A
PHE
0.83
1.00
0.37
10
85
A
PRO
0.94
0.47
0.54
8
86
A
PRO
0.43
0.47
0.67
8
87
A
LYS
0.46
0.25
0.75
8
88
A
VAL
0.61
0.56
0.56
8
92
A
LEU
0.45
0.70
0.49
8
94
A
ILE
0.34
0.64
0.57
8
95
A
GLN
0.40
0.43
0.65
8
96
A
TRP
0.71
0.99
0.44
10
97
A
GLY
0.50
0.41
0.65
8
98
A
SER
0.59
0.36
0.66
8
99
A
ASP
0.48
0.32
0.65
8
100
A
TRP
0.64
0.99
0.47
8
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.07
10
112
A
PHE
0.75
1.00
0.45
8
114
A
GLY
0.76
0.41
0.63
8
115
A
GLN
0.33
0.43
0.70
8
117
A
GLN
0.39
0.43
0.71
8
119
A
ILE
0.71
0.64
0.41
8
121
A
LEU
0.71
0.70
0.42
10
122
A
LEU
0.32
0.70
0.60
10
123
A
GLY
0.47
0.41
0.66
8
130
A
GLU
0.98
0.33
0.41
10
134
A
TRP
0.86
0.99
0.43
8
136
A
TRP
0.90
0.99
0.44
8
145
A
LEU
0.56
0.70
0.55
8
147
A
VAL
0.66
0.56
0.40
8
149
A
PHE
0.83
1.00
0.36
8
150
A
LYS
0.85
0.25
0.21
8
2
A
PRO
0.07
0.47
0.54
10
3
A
LEU
0.13
0.70
0.36
10
6
A
MET
0.21
0.66
0.48
10
7
A
ASP
0.18
0.32
0.60
10
8
A
SER
0.20
0.36
0.58
10
9
A
PRO
0.46
0.47
0.43
10
10
A
PRO
0.47
0.47
0.48
10
11
A
GLU
0.24
0.33
0.60
10
13
A
TYR
0.75
0.80
0.30
10
14
A
ARG
0.83
0.51
0.34
10
16
A
ASN
0.77
0.39
0.17
10
33
A
ARG
0.88
0.51
0.38
10
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.64
10
36
A
ILE
0.48
0.64
0.59
10
37
A
PRO
0.45
0.47
0.67
10
38
A
ASP
0.43
0.32
0.64
10
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.07
10
45
A
GLY
1.00
0.41
0.18
10
46
A
GLY
0.95
0.41
0.27
10
47
A
ILE
0.68
0.64
0.35
10
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.59
4
56
A
ALA
0.90
0.38
0.37
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.30
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.43
7
77
A
PRO
0.67
0.47
0.55
10
78
A
TYR
0.39
0.80
0.49
10
79
A
TRP
0.84
0.99
0.31
10
82
A
TYR
0.95
0.80
0.26
10
83
A
ASP
0.84
0.32
0.32
10
84
A
PHE
0.83
1.00
0.36
10
85
A
PRO
0.94
0.47
0.55
10
86
A
PRO
0.43
0.47
0.68
10
87
A
LYS
0.46
0.25
0.75
9
88
A
VAL
0.61
0.56
0.51
10
89
A
ARG
0.47
0.51
0.48
10
90
A
GLU
0.45
0.33
0.64
9
92
A
LEU
0.45
0.70
0.40
10
94
A
ILE
0.34
0.64
0.57
10
95
A
GLN
0.40
0.43
0.60
10
96
A
TRP
0.71
0.99
0.42
10
97
A
GLY
0.50
0.41
0.68
10
98
A
SER
0.59
0.36
0.65
10
99
A
ASP
0.48
0.32
0.61
10
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.06
10
115
A
GLN
0.33
0.43
0.69
9
117
A
GLN
0.39
0.43
0.70
10
119
A
ILE
0.71
0.64
0.41
10
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.60
10
130
A
GLU
0.98
0.33
0.38
10
131
A
PHE
0.96
1.00
0.31
10
134
A
TRP
0.86
0.99
0.42
10
136
A
TRP
0.90
0.99
0.42
10
137
A
VAL
0.44
0.56
0.44
10
145
A
LEU
0.56
0.70
0.53
10
147
A
VAL
0.66
0.56
0.39
9
149
A
PHE
0.83
1.00
0.37
10
150
A
LYS
0.85
0.25
0.21
3
2
A
PRO
0.07
0.47
0.51
9
3
A
LEU
0.13
0.70
0.35
9
4
A
GLY
0.10
0.41
0.48
9
6
A
MET
0.21
0.66
0.51
9
7
A
ASP
0.18
0.32
0.61
9
8
A
SER
0.20
0.36
0.58
9
11
A
GLU
0.24
0.33
0.64
9
13
A
TYR
0.75
0.80
0.33
10
14
A
ARG
0.83
0.51
0.38
9
15
A
ARG
0.62
0.51
0.40
2
24
A
ASN
0.30
0.39
0.66
9
33
A
ARG
0.88
0.51
0.39
10
34
A
LEU
0.46
0.70
0.54
10
35
A
ASP
0.70
0.32
0.59
10
36
A
ILE
0.48
0.64
0.55
10
37
A
PRO
0.45
0.47
0.66
10
38
A
ASP
0.43
0.32
0.64
9
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.21
9
44
A
GLN
0.94
0.43
0.06
10
45
A
GLY
1.00
0.41
0.18
10
46
A
GLY
0.95
0.41
0.27
10
49
A
GLU
0.45
0.33
0.66
9
50
A
GLY
0.74
0.41
0.67
8
51
A
GLU
1.00
0.33
0.59
7
56
A
ALA
0.90
0.38
0.37
10
59
A
ARG
1.00
0.51
0.52
10
60
A
GLU
1.00
0.33
0.28
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
73
A
ILE
0.51
0.64
0.53
9
77
A
PRO
0.67
0.47
0.52
9
78
A
TYR
0.39
0.80
0.48
10
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.25
10
84
A
PHE
0.83
1.00
0.34
10
85
A
PRO
0.94
0.47
0.53
9
86
A
PRO
0.43
0.47
0.68
9
87
A
LYS
0.46
0.25
0.76
8
88
A
VAL
0.61
0.56
0.52
9
92
A
LEU
0.45
0.70
0.35
10
94
A
ILE
0.34
0.64
0.59
9
95
A
GLN
0.40
0.43
0.55
9
96
A
TRP
0.71
0.99
0.40
10
97
A
GLY
0.50
0.41
0.65
9
98
A
SER
0.59
0.36
0.65
9
99
A
ASP
0.48
0.32
0.64
9
100
A
TRP
0.64
0.99
0.46
9
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.44
9
114
A
GLY
0.76
0.41
0.62
9
115
A
GLN
0.33
0.43
0.68
9
117
A
GLN
0.39
0.43
0.70
9
119
A
ILE
0.71
0.64
0.40
9
121
A
LEU
0.71
0.70
0.41
10
122
A
LEU
0.32
0.70
0.60
10
123
A
GLY
0.47
0.41
0.64
9
130
A
GLU
0.98
0.33
0.38
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
3
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.43
9
145
A
LEU
0.56
0.70
0.54
9
147
A
VAL
0.66
0.56
0.39
9
149
A
PHE
0.83
1.00
0.35
10
3
A
LEU
0.13
0.70
0.34
9
4
A
GLY
0.10
0.41
0.46
9
6
A
MET
0.21
0.66
0.51
9
7
A
ASP
0.18
0.32
0.62
9
8
A
SER
0.20
0.36
0.63
9
9
A
PRO
0.46
0.47
0.53
9
13
A
TYR
0.75
0.80
0.30
9
14
A
ARG
0.83
0.51
0.32
9
15
A
ARG
0.62
0.51
0.40
5
16
A
ASN
0.77
0.39
0.15
9
33
A
ARG
0.88
0.51
0.44
9
34
A
LEU
0.46
0.70
0.52
10
35
A
ASP
0.70
0.32
0.62
9
36
A
ILE
0.48
0.64
0.61
9
37
A
PRO
0.45
0.47
0.64
10
38
A
ASP
0.43
0.32
0.64
10
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.23
10
44
A
GLN
0.94
0.43
0.11
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.36
9
48
A
ASP
0.81
0.32
0.54
8
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.67
10
51
A
GLU
1.00
0.33
0.59
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.33
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
9
73
A
ILE
0.51
0.64
0.51
9
77
A
PRO
0.67
0.47
0.53
9
78
A
TYR
0.39
0.80
0.49
9
79
A
TRP
0.84
0.99
0.34
9
82
A
TYR
0.95
0.80
0.27
9
84
A
PHE
0.83
1.00
0.39
9
85
A
PRO
0.94
0.47
0.56
9
86
A
PRO
0.43
0.47
0.69
9
87
A
LYS
0.46
0.25
0.75
9
88
A
VAL
0.61
0.56
0.53
9
89
A
ARG
0.47
0.51
0.52
9
90
A
GLU
0.45
0.33
0.65
7
91
A
LYS
0.56
0.25
0.62
9
92
A
LEU
0.45
0.70
0.38
9
94
A
ILE
0.34
0.64
0.58
9
95
A
GLN
0.40
0.43
0.53
9
96
A
TRP
0.71
0.99
0.46
9
97
A
GLY
0.50
0.41
0.71
9
98
A
SER
0.59
0.36
0.72
9
99
A
ASP
0.48
0.32
0.63
9
100
A
TRP
0.64
0.99
0.46
9
103
A
GLN
0.95
0.43
0.18
9
112
A
PHE
0.75
1.00
0.44
9
115
A
GLN
0.33
0.43
0.68
9
116
A
ASP
0.58
0.32
0.59
9
117
A
GLN
0.39
0.43
0.72
9
119
A
ILE
0.71
0.64
0.42
9
121
A
LEU
0.71
0.70
0.42
10
122
A
LEU
0.32
0.70
0.49
10
123
A
GLY
0.47
0.41
0.64
9
130
A
GLU
0.98
0.33
0.36
10
132
A
GLY
0.68
0.41
0.49
5
134
A
TRP
0.86
0.99
0.42
10
136
A
TRP
0.90
0.99
0.45
9
141
A
GLN
0.35
0.43
0.58
9
145
A
LEU
0.56
0.70
0.54
10
147
A
VAL
0.66
0.56
0.39
9
149
A
PHE
0.83
1.00
0.37
10
150
A
LYS
0.85
0.25
0.21
1
3
A
LEU
0.13
0.70
0.32
10
6
A
MET
0.21
0.66
0.47
10
7
A
ASP
0.18
0.32
0.61
10
8
A
SER
0.20
0.36
0.61
10
9
A
PRO
0.46
0.47
0.46
10
10
A
PRO
0.47
0.47
0.49
10
11
A
GLU
0.24
0.33
0.61
10
13
A
TYR
0.75
0.80
0.33
10
14
A
ARG
0.83
0.51
0.36
10
15
A
ARG
0.62
0.51
0.42
1
16
A
ASN
0.77
0.39
0.21
10
23
A
ASN
0.80
0.39
0.49
2
24
A
ASN
0.30
0.39
0.65
10
33
A
ARG
0.88
0.51
0.43
10
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.58
10
37
A
PRO
0.45
0.47
0.65
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.38
10
49
A
GLU
0.45
0.33
0.67
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.60
10
56
A
ALA
0.90
0.38
0.39
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
10
73
A
ILE
0.51
0.64
0.51
10
77
A
PRO
0.67
0.47
0.53
10
78
A
TYR
0.39
0.80
0.47
10
79
A
TRP
0.84
0.99
0.34
10
82
A
TYR
0.95
0.80
0.15
10
84
A
PHE
0.83
1.00
0.36
10
85
A
PRO
0.94
0.47
0.56
10
86
A
PRO
0.43
0.47
0.67
10
87
A
LYS
0.46
0.25
0.75
10
88
A
VAL
0.61
0.56
0.52
10
92
A
LEU
0.45
0.70
0.40
10
94
A
ILE
0.34
0.64
0.61
10
95
A
GLN
0.40
0.43
0.62
10
96
A
TRP
0.71
0.99
0.45
10
97
A
GLY
0.50
0.41
0.72
10
98
A
SER
0.59
0.36
0.66
10
99
A
ASP
0.48
0.32
0.62
10
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.19
10
112
A
PHE
0.75
1.00
0.44
10
115
A
GLN
0.33
0.43
0.70
10
116
A
ASP
0.58
0.32
0.58
10
117
A
GLN
0.39
0.43
0.72
10
119
A
ILE
0.71
0.64
0.43
10
121
A
LEU
0.71
0.70
0.42
10
122
A
LEU
0.32
0.70
0.47
10
123
A
GLY
0.47
0.41
0.65
10
130
A
GLU
0.98
0.33
0.38
10
132
A
GLY
0.68
0.41
0.49
2
134
A
TRP
0.86
0.99
0.43
10
136
A
TRP
0.90
0.99
0.45
10
137
A
VAL
0.44
0.56
0.44
10
145
A
LEU
0.56
0.70
0.54
10
147
A
VAL
0.66
0.56
0.40
10
149
A
PHE
0.83
1.00
0.38
10
150
A
LYS
0.85
0.25
0.24
2
2
A
PRO
0.07
0.47
0.56
3
3
A
LEU
0.13
0.70
0.34
3
6
A
MET
0.21
0.66
0.47
3
7
A
ASP
0.18
0.32
0.62
3
8
A
SER
0.20
0.36
0.60
3
9
A
PRO
0.46
0.47
0.47
3
10
A
PRO
0.47
0.47
0.48
3
11
A
GLU
0.24
0.33
0.65
3
13
A
TYR
0.75
0.80
0.35
10
14
A
ARG
0.83
0.51
0.30
3
15
A
ARG
0.62
0.51
0.39
2
24
A
ASN
0.30
0.39
0.66
3
33
A
ARG
0.88
0.51
0.43
3
34
A
LEU
0.46
0.70
0.57
10
35
A
ASP
0.70
0.32
0.64
3
36
A
ILE
0.48
0.64
0.59
3
37
A
PRO
0.45
0.47
0.66
3
38
A
ASP
0.43
0.32
0.63
3
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.23
10
44
A
GLN
0.94
0.43
0.11
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.28
10
47
A
ILE
0.68
0.64
0.36
3
49
A
GLU
0.45
0.33
0.64
10
50
A
GLY
0.74
0.41
0.67
10
51
A
GLU
1.00
0.33
0.58
10
59
A
ARG
1.00
0.51
0.55
10
60
A
GLU
1.00
0.33
0.30
10
63
A
GLU
1.00
0.33
0.48
10
64
A
GLU
1.00
0.33
0.32
10
66
A
GLY
0.85
0.41
0.44
3
73
A
ILE
0.51
0.64
0.52
3
78
A
TYR
0.39
0.80
0.49
3
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.28
10
83
A
ASP
0.84
0.32
0.33
3
84
A
PHE
0.83
1.00
0.37
10
85
A
PRO
0.94
0.47
0.56
3
86
A
PRO
0.43
0.47
0.70
3
87
A
LYS
0.46
0.25
0.71
3
88
A
VAL
0.61
0.56
0.55
3
89
A
ARG
0.47
0.51
0.52
3
90
A
GLU
0.45
0.33
0.65
3
92
A
LEU
0.45
0.70
0.40
3
94
A
ILE
0.34
0.64
0.56
3
95
A
GLN
0.40
0.43
0.62
3
96
A
TRP
0.71
0.99
0.43
10
97
A
GLY
0.50
0.41
0.63
3
98
A
SER
0.59
0.36
0.67
3
99
A
ASP
0.48
0.32
0.58
3
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.08
10
112
A
PHE
0.75
1.00
0.44
3
115
A
GLN
0.33
0.43
0.68
3
116
A
ASP
0.58
0.32
0.59
3
117
A
GLN
0.39
0.43
0.71
3
119
A
ILE
0.71
0.64
0.41
3
120
A
ASN
0.62
0.39
0.58
3
122
A
LEU
0.32
0.70
0.61
10
130
A
GLU
0.98
0.33
0.40
10
134
A
TRP
0.86
0.99
0.42
3
136
A
TRP
0.90
0.99
0.45
3
145
A
LEU
0.56
0.70
0.55
3
147
A
VAL
0.66
0.56
0.40
3
149
A
PHE
0.83
1.00
0.35
10
153
A
VAL
0.73
0.56
0.20
3
3
A
LEU
0.13
0.70
0.34
10
6
A
MET
0.21
0.66
0.43
10
7
A
ASP
0.18
0.32
0.61
10
8
A
SER
0.20
0.36
0.60
10
9
A
PRO
0.46
0.47
0.51
10
13
A
TYR
0.75
0.80
0.25
10
14
A
ARG
0.83
0.51
0.32
10
16
A
ASN
0.77
0.39
0.20
10
33
A
ARG
0.88
0.51
0.45
10
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.62
10
36
A
ILE
0.48
0.64
0.61
10
37
A
PRO
0.45
0.47
0.65
10
38
A
ASP
0.43
0.32
0.64
10
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.24
10
44
A
GLN
0.94
0.43
0.11
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.36
10
49
A
GLU
0.45
0.33
0.65
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.60
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.44
9
77
A
PRO
0.67
0.47
0.53
10
78
A
TYR
0.39
0.80
0.46
10
79
A
TRP
0.84
0.99
0.31
10
82
A
TYR
0.95
0.80
0.19
10
83
A
ASP
0.84
0.32
0.24
10
84
A
PHE
0.83
1.00
0.35
10
85
A
PRO
0.94
0.47
0.52
10
86
A
PRO
0.43
0.47
0.63
10
87
A
LYS
0.46
0.25
0.75
10
88
A
VAL
0.61
0.56
0.54
10
89
A
ARG
0.47
0.51
0.54
10
90
A
GLU
0.45
0.33
0.68
5
91
A
LYS
0.56
0.25
0.69
10
92
A
LEU
0.45
0.70
0.40
10
94
A
ILE
0.34
0.64
0.61
10
95
A
GLN
0.40
0.43
0.61
10
96
A
TRP
0.71
0.99
0.43
10
97
A
GLY
0.50
0.41
0.69
10
98
A
SER
0.59
0.36
0.70
10
99
A
ASP
0.48
0.32
0.59
10
100
A
TRP
0.64
0.99
0.41
10
103
A
GLN
0.95
0.43
0.19
10
105
A
GLN
0.95
0.43
0.07
10
115
A
GLN
0.33
0.43
0.69
10
117
A
GLN
0.39
0.43
0.69
10
119
A
ILE
0.71
0.64
0.39
10
120
A
ASN
0.62
0.39
0.55
10
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.59
10
130
A
GLU
0.98
0.33
0.39
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
1
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
10
137
A
VAL
0.44
0.56
0.44
10
145
A
LEU
0.56
0.70
0.54
10
147
A
VAL
0.66
0.56
0.42
10
149
A
PHE
0.83
1.00
0.45
10
2
A
PRO
0.07
0.47
0.54
6
3
A
LEU
0.13
0.70
0.32
6
6
A
MET
0.21
0.66
0.48
6
7
A
ASP
0.18
0.32
0.58
6
8
A
SER
0.20
0.36
0.59
6
13
A
TYR
0.75
0.80
0.26
10
14
A
ARG
0.83
0.51
0.30
6
15
A
ARG
0.62
0.51
0.38
2
16
A
ASN
0.77
0.39
0.18
6
33
A
ARG
0.88
0.51
0.45
6
34
A
LEU
0.46
0.70
0.54
10
36
A
ILE
0.48
0.64
0.59
6
37
A
PRO
0.45
0.47
0.64
6
38
A
ASP
0.43
0.32
0.63
6
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.36
6
49
A
GLU
0.45
0.33
0.65
10
50
A
GLY
0.74
0.41
0.66
10
51
A
GLU
1.00
0.33
0.59
10
54
A
ARG
0.43
0.51
0.48
10
58
A
ILE
0.43
0.64
0.41
10
59
A
ARG
1.00
0.51
0.54
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.42
3
73
A
ILE
0.51
0.64
0.50
6
78
A
TYR
0.39
0.80
0.46
10
79
A
TRP
0.84
0.99
0.30
10
82
A
TYR
0.95
0.80
0.17
10
84
A
PHE
0.83
1.00
0.39
10
85
A
PRO
0.94
0.47
0.56
6
86
A
PRO
0.43
0.47
0.68
6
87
A
LYS
0.46
0.25
0.75
6
88
A
VAL
0.61
0.56
0.56
6
89
A
ARG
0.47
0.51
0.46
6
90
A
GLU
0.45
0.33
0.62
6
92
A
LEU
0.45
0.70
0.53
6
94
A
ILE
0.34
0.64
0.55
6
95
A
GLN
0.40
0.43
0.65
6
96
A
TRP
0.71
0.99
0.45
10
97
A
GLY
0.50
0.41
0.62
6
98
A
SER
0.59
0.36
0.65
6
99
A
ASP
0.48
0.32
0.63
6
100
A
TRP
0.64
0.99
0.42
10
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.44
6
114
A
GLY
0.76
0.41
0.61
6
115
A
GLN
0.33
0.43
0.68
6
117
A
GLN
0.39
0.43
0.70
6
119
A
ILE
0.71
0.64
0.40
6
121
A
LEU
0.71
0.70
0.39
10
122
A
LEU
0.32
0.70
0.58
10
130
A
GLU
0.98
0.33
0.40
10
134
A
TRP
0.86
0.99
0.41
6
136
A
TRP
0.90
0.99
0.43
6
145
A
LEU
0.56
0.70
0.54
6
147
A
VAL
0.66
0.56
0.39
6
149
A
PHE
0.83
1.00
0.36
10
2
A
PRO
0.07
0.47
0.53
10
3
A
LEU
0.13
0.70
0.34
10
6
A
MET
0.21
0.66
0.52
10
9
A
PRO
0.46
0.47
0.51
10
10
A
PRO
0.47
0.47
0.54
10
11
A
GLU
0.24
0.33
0.65
10
13
A
TYR
0.75
0.80
0.37
10
14
A
ARG
0.83
0.51
0.37
10
15
A
ARG
0.62
0.51
0.41
4
16
A
ASN
0.77
0.39
0.18
10
33
A
ARG
0.88
0.51
0.37
10
34
A
LEU
0.46
0.70
0.55
10
36
A
ILE
0.48
0.64
0.54
10
37
A
PRO
0.45
0.47
0.64
10
38
A
ASP
0.43
0.32
0.63
6
40
A
TRP
0.98
0.99
0.41
10
44
A
GLN
0.94
0.43
0.09
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.28
10
47
A
ILE
0.68
0.64
0.36
10
48
A
ASP
0.81
0.32
0.53
7
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.68
10
51
A
GLU
1.00
0.33
0.59
10
54
A
ARG
0.43
0.51
0.48
10
59
A
ARG
1.00
0.51
0.52
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.42
10
78
A
TYR
0.39
0.80
0.49
10
82
A
TYR
0.95
0.80
0.12
10
84
A
PHE
0.83
1.00
0.32
10
85
A
PRO
0.94
0.47
0.53
10
86
A
PRO
0.43
0.47
0.68
10
87
A
LYS
0.46
0.25
0.73
8
88
A
VAL
0.61
0.56
0.48
10
90
A
GLU
0.45
0.33
0.66
8
91
A
LYS
0.56
0.25
0.61
8
92
A
LEU
0.45
0.70
0.37
10
94
A
ILE
0.34
0.64
0.62
10
95
A
GLN
0.40
0.43
0.59
10
96
A
TRP
0.71
0.99
0.42
10
97
A
GLY
0.50
0.41
0.66
10
98
A
SER
0.59
0.36
0.71
10
99
A
ASP
0.48
0.32
0.67
10
100
A
TRP
0.64
0.99
0.48
10
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.07
10
115
A
GLN
0.33
0.43
0.69
10
117
A
GLN
0.39
0.43
0.69
10
119
A
ILE
0.71
0.64
0.39
10
121
A
LEU
0.71
0.70
0.39
10
122
A
LEU
0.32
0.70
0.59
10
130
A
GLU
0.98
0.33
0.41
10
131
A
PHE
0.96
1.00
0.31
10
132
A
GLY
0.68
0.41
0.50
10
134
A
TRP
0.86
0.99
0.40
10
135
A
SER
0.51
0.36
0.45
10
136
A
TRP
0.90
0.99
0.44
10
137
A
VAL
0.44
0.56
0.44
10
141
A
GLN
0.35
0.43
0.58
1
145
A
LEU
0.56
0.70
0.54
6
147
A
VAL
0.66
0.56
0.35
6
149
A
PHE
0.83
1.00
0.35
10
150
A
LYS
0.85
0.25
0.20
9
1
A
GLY
0.07
0.41
0.51
9
2
A
PRO
0.07
0.47
0.54
9
3
A
LEU
0.13
0.70
0.33
9
9
A
PRO
0.46
0.47
0.48
9
13
A
TYR
0.75
0.80
0.30
9
14
A
ARG
0.83
0.51
0.31
9
15
A
ARG
0.62
0.51
0.40
1
16
A
ASN
0.77
0.39
0.18
9
24
A
ASN
0.30
0.39
0.65
9
33
A
ARG
0.88
0.51
0.43
9
34
A
LEU
0.46
0.70
0.52
10
35
A
ASP
0.70
0.32
0.62
9
36
A
ILE
0.48
0.64
0.58
9
37
A
PRO
0.45
0.47
0.64
9
38
A
ASP
0.43
0.32
0.64
9
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.22
10
44
A
GLN
0.94
0.43
0.07
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.29
10
47
A
ILE
0.68
0.64
0.37
9
48
A
ASP
0.81
0.32
0.54
1
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.67
10
51
A
GLU
1.00
0.33
0.59
10
54
A
ARG
0.43
0.51
0.48
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.29
10
73
A
ILE
0.51
0.64
0.52
9
82
A
TYR
0.95
0.80
0.23
9
83
A
ASP
0.84
0.32
0.30
6
84
A
PHE
0.83
1.00
0.39
9
85
A
PRO
0.94
0.47
0.54
6
86
A
PRO
0.43
0.47
0.67
5
87
A
LYS
0.46
0.25
0.72
3
88
A
VAL
0.61
0.56
0.56
5
90
A
GLU
0.45
0.33
0.62
3
92
A
LEU
0.45
0.70
0.47
9
94
A
ILE
0.34
0.64
0.55
9
95
A
GLN
0.40
0.43
0.64
9
96
A
TRP
0.71
0.99
0.42
9
97
A
GLY
0.50
0.41
0.65
9
98
A
SER
0.59
0.36
0.65
9
99
A
ASP
0.48
0.32
0.59
9
100
A
TRP
0.64
0.99
0.42
9
103
A
GLN
0.95
0.43
0.16
9
112
A
PHE
0.75
1.00
0.44
9
114
A
GLY
0.76
0.41
0.62
9
115
A
GLN
0.33
0.43
0.69
9
117
A
GLN
0.39
0.43
0.70
9
119
A
ILE
0.71
0.64
0.40
9
121
A
LEU
0.71
0.70
0.41
10
122
A
LEU
0.32
0.70
0.51
10
123
A
GLY
0.47
0.41
0.67
9
130
A
GLU
0.98
0.33
0.38
10
132
A
GLY
0.68
0.41
0.47
4
134
A
TRP
0.86
0.99
0.41
9
136
A
TRP
0.90
0.99
0.41
9
145
A
LEU
0.56
0.70
0.53
9
147
A
VAL
0.66
0.56
0.38
9
149
A
PHE
0.83
1.00
0.33
10
150
A
LYS
0.85
0.25
0.20
8
2
A
PRO
0.07
0.47
0.51
9
3
A
LEU
0.13
0.70
0.39
9
4
A
GLY
0.10
0.41
0.47
9
6
A
MET
0.21
0.66
0.47
9
7
A
ASP
0.18
0.32
0.60
9
8
A
SER
0.20
0.36
0.62
9
9
A
PRO
0.46
0.47
0.47
9
13
A
TYR
0.75
0.80
0.29
9
14
A
ARG
0.83
0.51
0.32
9
16
A
ASN
0.77
0.39
0.17
9
24
A
ASN
0.30
0.39
0.65
9
33
A
ARG
0.88
0.51
0.43
9
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.63
9
36
A
ILE
0.48
0.64
0.58
9
37
A
PRO
0.45
0.47
0.65
9
38
A
ASP
0.43
0.32
0.64
9
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.21
10
44
A
GLN
0.94
0.43
0.08
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.29
10
47
A
ILE
0.68
0.64
0.35
9
49
A
GLU
0.45
0.33
0.65
10
50
A
GLY
0.74
0.41
0.66
10
51
A
GLU
1.00
0.33
0.59
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.30
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.42
5
73
A
ILE
0.51
0.64
0.51
9
77
A
PRO
0.67
0.47
0.53
9
78
A
TYR
0.39
0.80
0.47
9
79
A
TRP
0.84
0.99
0.31
9
82
A
TYR
0.95
0.80
0.20
10
83
A
ASP
0.84
0.32
0.30
9
84
A
PHE
0.83
1.00
0.34
9
85
A
PRO
0.94
0.47
0.47
9
86
A
PRO
0.43
0.47
0.62
7
87
A
LYS
0.46
0.25
0.74
3
88
A
VAL
0.61
0.56
0.54
7
89
A
ARG
0.47
0.51
0.50
9
92
A
LEU
0.45
0.70
0.44
9
94
A
ILE
0.34
0.64
0.57
9
95
A
GLN
0.40
0.43
0.63
9
96
A
TRP
0.71
0.99
0.46
9
97
A
GLY
0.50
0.41
0.69
9
98
A
SER
0.59
0.36
0.70
9
99
A
ASP
0.48
0.32
0.62
9
100
A
TRP
0.64
0.99
0.41
9
103
A
GLN
0.95
0.43
0.17
9
112
A
PHE
0.75
1.00
0.44
9
114
A
GLY
0.76
0.41
0.62
9
115
A
GLN
0.33
0.43
0.69
9
117
A
GLN
0.39
0.43
0.71
9
119
A
ILE
0.71
0.64
0.41
9
122
A
LEU
0.32
0.70
0.60
10
130
A
GLU
0.98
0.33
0.38
10
131
A
PHE
0.96
1.00
0.31
10
132
A
GLY
0.68
0.41
0.50
1
134
A
TRP
0.86
0.99
0.42
10
136
A
TRP
0.90
0.99
0.43
9
145
A
LEU
0.56
0.70
0.53
9
147
A
VAL
0.66
0.56
0.38
8
149
A
PHE
0.83
1.00
0.40
9
150
A
LYS
0.85
0.25
0.23
2
1
A
GLY
0.07
0.41
0.52
7
2
A
PRO
0.07
0.47
0.53
7
3
A
LEU
0.13
0.70
0.34
7
6
A
MET
0.21
0.66
0.48
7
7
A
ASP
0.18
0.32
0.61
7
8
A
SER
0.20
0.36
0.61
7
9
A
PRO
0.46
0.47
0.49
7
10
A
PRO
0.47
0.47
0.48
7
11
A
GLU
0.24
0.33
0.64
7
13
A
TYR
0.75
0.80
0.33
10
14
A
ARG
0.83
0.51
0.33
7
16
A
ASN
0.77
0.39
0.19
7
33
A
ARG
0.88
0.51
0.46
10
34
A
LEU
0.46
0.70
0.57
10
35
A
ASP
0.70
0.32
0.67
7
36
A
ILE
0.48
0.64
0.62
7
37
A
PRO
0.45
0.47
0.67
7
38
A
ASP
0.43
0.32
0.64
7
40
A
TRP
0.98
0.99
0.42
10
41
A
GLN
0.92
0.43
0.26
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.22
10
46
A
GLY
0.95
0.41
0.31
10
47
A
ILE
0.68
0.64
0.36
7
49
A
GLU
0.45
0.33
0.65
10
50
A
GLY
0.74
0.41
0.66
10
51
A
GLU
1.00
0.33
0.59
10
54
A
ARG
0.43
0.51
0.49
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.31
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.42
2
73
A
ILE
0.51
0.64
0.52
7
77
A
PRO
0.67
0.47
0.53
7
78
A
TYR
0.39
0.80
0.47
10
79
A
TRP
0.84
0.99
0.32
10
82
A
TYR
0.95
0.80
0.25
10
84
A
PHE
0.83
1.00
0.37
10
85
A
PRO
0.94
0.47
0.56
7
86
A
PRO
0.43
0.47
0.68
7
87
A
LYS
0.46
0.25
0.74
7
88
A
VAL
0.61
0.56
0.52
7
94
A
ILE
0.34
0.64
0.62
7
95
A
GLN
0.40
0.43
0.57
7
96
A
TRP
0.71
0.99
0.45
10
97
A
GLY
0.50
0.41
0.69
7
98
A
SER
0.59
0.36
0.66
7
99
A
ASP
0.48
0.32
0.64
7
100
A
TRP
0.64
0.99
0.45
10
103
A
GLN
0.95
0.43
0.18
10
105
A
GLN
0.95
0.43
0.07
10
112
A
PHE
0.75
1.00
0.45
7
114
A
GLY
0.76
0.41
0.63
7
115
A
GLN
0.33
0.43
0.70
7
117
A
GLN
0.39
0.43
0.71
7
119
A
ILE
0.71
0.64
0.42
7
122
A
LEU
0.32
0.70
0.60
10
130
A
GLU
0.98
0.33
0.41
10
131
A
PHE
0.96
1.00
0.32
10
134
A
TRP
0.86
0.99
0.43
10
136
A
TRP
0.90
0.99
0.43
7
145
A
LEU
0.56
0.70
0.54
7
147
A
VAL
0.66
0.56
0.41
7
149
A
PHE
0.83
1.00
0.37
10
153
A
VAL
0.73
0.56
0.21
7
3
A
LEU
0.13
0.70
0.39
10
4
A
GLY
0.10
0.41
0.44
10
6
A
MET
0.21
0.66
0.50
10
11
A
GLU
0.24
0.33
0.63
10
13
A
TYR
0.75
0.80
0.33
10
14
A
ARG
0.83
0.51
0.26
10
16
A
ASN
0.77
0.39
0.15
10
33
A
ARG
0.88
0.51
0.43
10
34
A
LEU
0.46
0.70
0.54
10
36
A
ILE
0.48
0.64
0.59
10
37
A
PRO
0.45
0.47
0.64
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.23
10
44
A
GLN
0.94
0.43
0.08
10
45
A
GLY
1.00
0.41
0.19
10
46
A
GLY
0.95
0.41
0.27
10
47
A
ILE
0.68
0.64
0.34
10
48
A
ASP
0.81
0.32
0.52
2
49
A
GLU
0.45
0.33
0.63
10
50
A
GLY
0.74
0.41
0.65
8
51
A
GLU
1.00
0.33
0.58
8
54
A
ARG
0.43
0.51
0.46
10
58
A
ILE
0.43
0.64
0.41
10
59
A
ARG
1.00
0.51
0.54
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.48
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
9
72
A
VAL
0.58
0.56
0.48
10
82
A
TYR
0.95
0.80
0.23
10
83
A
ASP
0.84
0.32
0.35
10
84
A
PHE
0.83
1.00
0.31
10
85
A
PRO
0.94
0.47
0.45
10
86
A
PRO
0.43
0.47
0.63
10
87
A
LYS
0.46
0.25
0.76
10
88
A
VAL
0.61
0.56
0.49
10
89
A
ARG
0.47
0.51
0.50
10
90
A
GLU
0.45
0.33
0.62
4
91
A
LYS
0.56
0.25
0.70
10
92
A
LEU
0.45
0.70
0.45
10
94
A
ILE
0.34
0.64
0.55
10
95
A
GLN
0.40
0.43
0.62
10
96
A
TRP
0.71
0.99
0.41
10
97
A
GLY
0.50
0.41
0.67
10
98
A
SER
0.59
0.36
0.69
10
99
A
ASP
0.48
0.32
0.61
10
100
A
TRP
0.64
0.99
0.42
10
103
A
GLN
0.95
0.43
0.17
10
105
A
GLN
0.95
0.43
0.06
10
108
A
PHE
0.82
1.00
0.24
10
115
A
GLN
0.33
0.43
0.68
10
117
A
GLN
0.39
0.43
0.71
10
119
A
ILE
0.71
0.64
0.40
10
122
A
LEU
0.32
0.70
0.59
10
123
A
GLY
0.47
0.41
0.61
10
130
A
GLU
0.98
0.33
0.40
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
10
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
10
137
A
VAL
0.44
0.56
0.44
10
145
A
LEU
0.56
0.70
0.54
10
147
A
VAL
0.66
0.56
0.39
10
149
A
PHE
0.83
1.00
0.36
10
150
A
LYS
0.85
0.25
0.22
10
1
A
GLY
0.07
0.41
0.60
10
3
A
LEU
0.13
0.70
0.38
10
6
A
MET
0.21
0.66
0.51
10
7
A
ASP
0.18
0.32
0.61
10
8
A
SER
0.20
0.36
0.60
10
10
A
PRO
0.47
0.47
0.54
10
11
A
GLU
0.24
0.33
0.64
10
13
A
TYR
0.75
0.80
0.36
10
14
A
ARG
0.83
0.51
0.34
10
24
A
ASN
0.30
0.39
0.65
10
33
A
ARG
0.88
0.51
0.39
10
34
A
LEU
0.46
0.70
0.54
10
36
A
ILE
0.48
0.64
0.54
10
37
A
PRO
0.45
0.47
0.64
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.41
10
44
A
GLN
0.94
0.43
0.08
10
45
A
GLY
1.00
0.41
0.20
10
46
A
GLY
0.95
0.41
0.28
10
47
A
ILE
0.68
0.64
0.35
10
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.67
9
51
A
GLU
1.00
0.33
0.59
9
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.47
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.42
10
73
A
ILE
0.51
0.64
0.53
10
77
A
PRO
0.67
0.47
0.54
10
78
A
TYR
0.39
0.80
0.48
10
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.23
10
84
A
PHE
0.83
1.00
0.32
10
85
A
PRO
0.94
0.47
0.50
10
86
A
PRO
0.43
0.47
0.66
10
88
A
VAL
0.61
0.56
0.45
10
92
A
LEU
0.45
0.70
0.42
10
94
A
ILE
0.34
0.64
0.62
10
95
A
GLN
0.40
0.43
0.63
10
96
A
TRP
0.71
0.99
0.44
10
97
A
GLY
0.50
0.41
0.68
10
98
A
SER
0.59
0.36
0.67
10
99
A
ASP
0.48
0.32
0.66
10
100
A
TRP
0.64
0.99
0.47
10
103
A
GLN
0.95
0.43
0.18
10
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.44
10
114
A
GLY
0.76
0.41
0.62
10
115
A
GLN
0.33
0.43
0.68
10
116
A
ASP
0.58
0.32
0.58
10
117
A
GLN
0.39
0.43
0.69
10
119
A
ILE
0.71
0.64
0.39
10
121
A
LEU
0.71
0.70
0.41
10
122
A
LEU
0.32
0.70
0.58
10
123
A
GLY
0.47
0.41
0.63
10
130
A
GLU
0.98
0.33
0.40
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
10
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
10
137
A
VAL
0.44
0.56
0.44
10
145
A
LEU
0.56
0.70
0.54
10
147
A
VAL
0.66
0.56
0.36
10
149
A
PHE
0.83
1.00
0.32
10
150
A
LYS
0.85
0.25
0.20
5
2
A
PRO
0.07
0.47
0.49
10
3
A
LEU
0.13
0.70
0.34
10
6
A
MET
0.21
0.66
0.47
10
7
A
ASP
0.18
0.32
0.60
10
8
A
SER
0.20
0.36
0.59
10
11
A
GLU
0.24
0.33
0.61
10
13
A
TYR
0.75
0.80
0.31
10
14
A
ARG
0.83
0.51
0.30
10
16
A
ASN
0.77
0.39
0.18
10
33
A
ARG
0.88
0.51
0.44
10
34
A
LEU
0.46
0.70
0.55
10
35
A
ASP
0.70
0.32
0.65
10
36
A
ILE
0.48
0.64
0.59
10
37
A
PRO
0.45
0.47
0.66
10
38
A
ASP
0.43
0.32
0.63
10
40
A
TRP
0.98
0.99
0.40
10
41
A
GLN
0.92
0.43
0.23
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.21
10
46
A
GLY
0.95
0.41
0.30
10
47
A
ILE
0.68
0.64
0.36
10
49
A
GLU
0.45
0.33
0.66
10
50
A
GLY
0.74
0.41
0.66
10
51
A
GLU
1.00
0.33
0.58
10
59
A
ARG
1.00
0.51
0.53
10
60
A
GLU
1.00
0.33
0.32
10
63
A
GLU
1.00
0.33
0.46
10
64
A
GLU
1.00
0.33
0.30
10
66
A
GLY
0.85
0.41
0.42
10
73
A
ILE
0.51
0.64
0.51
10
77
A
PRO
0.67
0.47
0.54
10
78
A
TYR
0.39
0.80
0.48
10
79
A
TRP
0.84
0.99
0.33
10
82
A
TYR
0.95
0.80
0.24
10
83
A
ASP
0.84
0.32
0.29
10
84
A
PHE
0.83
1.00
0.38
10
85
A
PRO
0.94
0.47
0.55
10
86
A
PRO
0.43
0.47
0.68
10
87
A
LYS
0.46
0.25
0.74
10
88
A
VAL
0.61
0.56
0.54
10
89
A
ARG
0.47
0.51
0.50
10
92
A
LEU
0.45
0.70
0.43
10
94
A
ILE
0.34
0.64
0.54
10
95
A
GLN
0.40
0.43
0.63
10
96
A
TRP
0.71
0.99
0.42
10
97
A
GLY
0.50
0.41
0.68
10
98
A
SER
0.59
0.36
0.67
10
99
A
ASP
0.48
0.32
0.62
10
100
A
TRP
0.64
0.99
0.44
10
103
A
GLN
0.95
0.43
0.14
10
105
A
GLN
0.95
0.43
0.06
10
112
A
PHE
0.75
1.00
0.44
10
115
A
GLN
0.33
0.43
0.69
10
116
A
ASP
0.58
0.32
0.57
10
117
A
GLN
0.39
0.43
0.71
10
119
A
ILE
0.71
0.64
0.41
10
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.57
10
130
A
GLU
0.98
0.33
0.40
10
131
A
PHE
0.96
1.00
0.30
10
132
A
GLY
0.68
0.41
0.49
1
134
A
TRP
0.86
0.99
0.41
10
136
A
TRP
0.90
0.99
0.44
10
145
A
LEU
0.56
0.70
0.53
10
147
A
VAL
0.66
0.56
0.38
10
149
A
PHE
0.83
1.00
0.37
10
150
A
LYS
0.85
0.25
0.20
6
2
A
PRO
0.07
0.47
0.55
3
3
A
LEU
0.13
0.70
0.34
3
6
A
MET
0.21
0.66
0.48
3
7
A
ASP
0.18
0.32
0.62
3
8
A
SER
0.20
0.36
0.61
3
9
A
PRO
0.46
0.47
0.50
3
13
A
TYR
0.75
0.80
0.32
10
14
A
ARG
0.83
0.51
0.33
3
16
A
ASN
0.77
0.39
0.21
3
24
A
ASN
0.30
0.39
0.66
3
33
A
ARG
0.88
0.51
0.42
3
34
A
LEU
0.46
0.70
0.55
9
36
A
ILE
0.48
0.64
0.56
3
37
A
PRO
0.45
0.47
0.64
3
38
A
ASP
0.43
0.32
0.63
3
40
A
TRP
0.98
0.99
0.41
10
41
A
GLN
0.92
0.43
0.23
10
44
A
GLN
0.94
0.43
0.10
10
45
A
GLY
1.00
0.41
0.22
10
46
A
GLY
0.95
0.41
0.32
10
47
A
ILE
0.68
0.64
0.39
3
49
A
GLU
0.45
0.33
0.69
10
50
A
GLY
0.74
0.41
0.71
10
51
A
GLU
1.00
0.33
0.61
10
54
A
ARG
0.43
0.51
0.48
10
58
A
ILE
0.43
0.64
0.42
10
59
A
ARG
1.00
0.51
0.52
10
60
A
GLU
1.00
0.33
0.33
10
63
A
GLU
1.00
0.33
0.48
10
64
A
GLU
1.00
0.33
0.31
10
66
A
GLY
0.85
0.41
0.43
3
73
A
ILE
0.51
0.64
0.53
3
77
A
PRO
0.67
0.47
0.54
3
78
A
TYR
0.39
0.80
0.49
3
79
A
TRP
0.84
0.99
0.34
10
82
A
TYR
0.95
0.80
0.25
10
83
A
ASP
0.84
0.32
0.29
3
84
A
PHE
0.83
1.00
0.37
3
85
A
PRO
0.94
0.47
0.55
3
86
A
PRO
0.43
0.47
0.67
3
87
A
LYS
0.46
0.25
0.76
3
88
A
VAL
0.61
0.56
0.53
3
90
A
GLU
0.45
0.33
0.67
3
91
A
LYS
0.56
0.25
0.64
1
92
A
LEU
0.45
0.70
0.38
10
94
A
ILE
0.34
0.64
0.62
3
95
A
GLN
0.40
0.43
0.57
3
96
A
TRP
0.71
0.99
0.46
10
97
A
GLY
0.50
0.41
0.71
3
98
A
SER
0.59
0.36
0.65
3
99
A
ASP
0.48
0.32
0.56
3
100
A
TRP
0.64
0.99
0.43
10
103
A
GLN
0.95
0.43
0.18
10
105
A
GLN
0.95
0.43
0.08
10
112
A
PHE
0.75
1.00
0.45
3
115
A
GLN
0.33
0.43
0.68
3
116
A
ASP
0.58
0.32
0.58
3
117
A
GLN
0.39
0.43
0.71
3
119
A
ILE
0.71
0.64
0.41
3
121
A
LEU
0.71
0.70
0.40
10
122
A
LEU
0.32
0.70
0.58
10
130
A
GLU
0.98
0.33
0.40
9
134
A
TRP
0.86
0.99
0.41
3
136
A
TRP
0.90
0.99
0.44
3
145
A
LEU
0.56
0.70
0.54
3
147
A
VAL
0.66
0.56
0.37
3
149
A
PHE
0.83
1.00
0.32
10