Pre-computed interfaces

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JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1F6V chain A sc2

 

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 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
GLY
0.00
0.41
0.91
10
2
A
SER
0.91
0.36
0.87
10
3
A
ARG
1.00
0.51
0.84
10
4
A
ILE
0.65
0.64
0.81
10
5
A
ALA
0.79
0.38
0.73
10
6
A
LYS
0.68
0.25
0.80
10
7
A
ARG
0.55
0.51
0.74
10
8
A
THR
0.33
0.33
0.74
10
9
A
ALA
0.53
0.38
0.65
6
10
A
ILE
0.65
0.64
0.66
10
12
A
LYS
0.64
0.25
0.23
1
13
A
THR
0.53
0.33
0.60
7
14
A
LYS
0.76
0.25
0.71
10
15
A
LYS
0.32
0.25
0.75
10
17
A
ASP
1.00
0.32
0.47
10
18
A
VAL
0.79
0.56
0.53
10
22
A
ALA
0.82
0.38
0.45
4
24
A
ALA
1.00
0.38
0.25
2
25
A
TRP
1.00
0.99
0.15
9
27
A
ILE
0.46
0.64
0.54
7
28
A
ASN
0.26
0.39
0.72
4
29
A
GLY
0.56
0.41
0.69
4
30
A
GLU
0.37
0.33
0.77
1
33
A
LEU
0.30
0.70
0.67
5
34
A
GLU
0.29
0.33
0.68
4
35
A
LEU
0.59
0.70
0.43
10
36
A
LEU
0.70
0.70
0.43
10
37
A
GLN
0.40
0.43
0.69
10
38
A
GLN
0.31
0.43
0.68
10
39
A
ILE
0.91
0.64
0.42
4
40
A
ALA
0.67
0.38
0.47
10
41
A
GLN
0.51
0.43
0.64
10
42
A
LYS
0.52
0.25
0.62
2
43
A
PRO
0.76
0.47
0.47
6
44
A
GLY
1.00
0.41
0.55
8
45
A
ALA
0.74
0.38
0.49
10
46
A
LEU
0.82
0.70
0.26
10
47
A
ARG
0.97
0.51
0.53
10
48
A
ILE
0.45
0.64
0.54
10
49
A
LEU
0.62
0.70
0.30
10
51
A
HIS
0.48
0.60
0.44
10
53
A
LEU
0.90
0.70
0.00
7
54
A
ARG
0.60
0.51
0.41
9
56
A
ALA
1.00
0.38
0.16
8
57
A
ALA
0.45
0.38
0.43
8
58
A
MET
0.67
0.66
0.49
8
59
A
THR
0.36
0.33
0.62
8
60
A
ALA
1.00
0.38
0.68
8
61
A
HIS
0.33
0.60
0.57
8
62
A
GLY
0.81
0.41
0.74
8
63
A
LYS
0.29
0.25
0.74
1
64
A
GLY
0.62
0.41
0.67
8
65
A
GLU
0.08
0.33
0.64
8
66
A
ARG
0.37
0.51
0.73
8
67
A
VAL
0.55
0.56
0.74
2
68
A
ASN
0.27
0.39
0.70
2
69
A
GLU
0.69
0.33
0.65
4
70
A
ASP
0.27
0.32
0.64
2
71
A
TYR
0.50
0.80
0.47
8
73
A
ARG
0.43
0.51
0.53
10
74
A
GLN
0.22
0.43
0.60
8
76
A
PHE
0.40
1.00
0.25
10
77
A
ARG
0.46
0.51
0.56
10
79
A
LEU
0.71
0.70
0.56
8
80
A
ASP
0.49
0.32
0.63
2
81
A
LEU
0.32
0.70
0.46
7
82
A
ASP
0.53
0.32
0.67
2
83
A
VAL
0.49
0.56
0.73
2
85
A
ILE
0.16
0.64
0.47
7
87
A
THR
0.18
0.33
0.71
2
89
A
LEU
0.42
0.70
0.74
1
1
A
GLY
0.00
0.41
0.91
10
2
A
SER
0.91
0.36
0.91
10
3
A
ARG
1.00
0.51
0.88
10
4
A
ILE
0.65
0.64
0.84
10
5
A
ALA
0.79
0.38
0.76
10
6
A
LYS
0.68
0.25
0.81
10
7
A
ARG
0.55
0.51
0.71
10
8
A
THR
0.33
0.33
0.73
10
9
A
ALA
0.53
0.38
0.64
10
10
A
ILE
0.65
0.64
0.62
10
13
A
THR
0.53
0.33
0.52
10
14
A
LYS
0.76
0.25
0.59
10
15
A
LYS
0.32
0.25
0.69
10
17
A
ASP
1.00
0.32
0.37
10
18
A
VAL
0.79
0.56
0.48
10
22
A
ALA
0.82
0.38
0.40
5
25
A
TRP
1.00
0.99
0.15
10
26
A
GLN
0.35
0.43
0.57
10
27
A
ILE
0.46
0.64
0.52
9
28
A
ASN
0.26
0.39
0.70
8
29
A
GLY
0.56
0.41
0.68
8
30
A
GLU
0.37
0.33
0.77
2
32
A
GLU
0.74
0.33
0.51
1
33
A
LEU
0.30
0.70
0.68
6
34
A
GLU
0.29
0.33
0.67
9
35
A
LEU
0.59
0.70
0.42
10
36
A
LEU
0.70
0.70
0.46
10
37
A
GLN
0.40
0.43
0.70
10
38
A
GLN
0.31
0.43
0.67
10
39
A
ILE
0.91
0.64
0.41
10
40
A
ALA
0.67
0.38
0.51
10
41
A
GLN
0.51
0.43
0.67
10
42
A
LYS
0.52
0.25
0.61
10
43
A
PRO
0.76
0.47
0.49
10
44
A
GLY
1.00
0.41
0.57
10
45
A
ALA
0.74
0.38
0.46
10
46
A
LEU
0.82
0.70
0.28
10
47
A
ARG
0.97
0.51
0.57
10
48
A
ILE
0.45
0.64
0.50
10
49
A
LEU
0.62
0.70
0.26
10
50
A
ASN
0.42
0.39
0.30
1
51
A
HIS
0.48
0.60
0.46
10
54
A
ARG
0.60
0.51
0.47
10
56
A
ALA
1.00
0.38
0.22
9
57
A
ALA
0.45
0.38
0.48
10
58
A
MET
0.67
0.66
0.54
10
59
A
THR
0.36
0.33
0.66
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.58
10
62
A
GLY
0.81
0.41
0.73
10
63
A
LYS
0.29
0.25
0.76
1
65
A
GLU
0.08
0.33
0.63
10
66
A
ARG
0.37
0.51
0.72
3
67
A
VAL
0.55
0.56
0.72
3
68
A
ASN
0.27
0.39
0.68
3
70
A
ASP
0.27
0.32
0.61
8
71
A
TYR
0.50
0.80
0.48
10
73
A
ARG
0.43
0.51
0.52
10
74
A
GLN
0.22
0.43
0.58
3
77
A
ARG
0.46
0.51
0.52
10
79
A
LEU
0.71
0.70
0.57
1
80
A
ASP
0.49
0.32
0.61
2
81
A
LEU
0.32
0.70
0.43
6
82
A
ASP
0.53
0.32
0.66
2
83
A
VAL
0.49
0.56
0.73
2
85
A
ILE
0.16
0.64
0.47
10
87
A
THR
0.18
0.33
0.73
2
89
A
LEU
0.42
0.70
0.74
1
90
A
ARG
0.23
0.51
0.86
1
1
A
GLY
0.00
0.41
0.90
10
2
A
SER
0.91
0.36
0.85
10
3
A
ARG
1.00
0.51
0.86
10
4
A
ILE
0.65
0.64
0.75
10
5
A
ALA
0.79
0.38
0.71
10
6
A
LYS
0.68
0.25
0.80
10
7
A
ARG
0.55
0.51
0.66
9
8
A
THR
0.33
0.33
0.76
10
9
A
ALA
0.53
0.38
0.69
10
10
A
ILE
0.65
0.64
0.68
10
12
A
LYS
0.64
0.25
0.24
1
13
A
THR
0.53
0.33
0.57
6
14
A
LYS
0.76
0.25
0.58
10
15
A
LYS
0.32
0.25
0.69
10
17
A
ASP
1.00
0.32
0.39
6
18
A
VAL
0.79
0.56
0.49
10
22
A
ALA
0.82
0.38
0.43
1
25
A
TRP
1.00
0.99
0.19
10
26
A
GLN
0.35
0.43
0.59
10
27
A
ILE
0.46
0.64
0.55
10
28
A
ASN
0.26
0.39
0.73
9
29
A
GLY
0.56
0.41
0.71
9
30
A
GLU
0.37
0.33
0.80
3
31
A
LYS
0.23
0.25
0.74
3
33
A
LEU
0.30
0.70
0.71
5
34
A
GLU
0.29
0.33
0.71
10
35
A
LEU
0.59
0.70
0.48
10
36
A
LEU
0.70
0.70
0.52
10
37
A
GLN
0.40
0.43
0.74
10
38
A
GLN
0.31
0.43
0.73
10
39
A
ILE
0.91
0.64
0.48
10
40
A
ALA
0.67
0.38
0.57
10
41
A
GLN
0.51
0.43
0.72
10
42
A
LYS
0.52
0.25
0.68
9
43
A
PRO
0.76
0.47
0.54
10
44
A
GLY
1.00
0.41
0.60
10
45
A
ALA
0.74
0.38
0.47
9
46
A
LEU
0.82
0.70
0.30
10
47
A
ARG
0.97
0.51
0.56
10
48
A
ILE
0.45
0.64
0.47
10
49
A
LEU
0.62
0.70
0.23
10
51
A
HIS
0.48
0.60
0.43
10
54
A
ARG
0.60
0.51
0.47
10
56
A
ALA
1.00
0.38
0.26
10
57
A
ALA
0.45
0.38
0.51
10
58
A
MET
0.67
0.66
0.55
10
59
A
THR
0.36
0.33
0.66
10
60
A
ALA
1.00
0.38
0.72
10
61
A
HIS
0.33
0.60
0.60
10
62
A
GLY
0.81
0.41
0.76
10
63
A
LYS
0.29
0.25
0.75
4
64
A
GLY
0.62
0.41
0.64
10
66
A
ARG
0.37
0.51
0.72
10
67
A
VAL
0.55
0.56
0.75
4
68
A
ASN
0.27
0.39
0.72
4
69
A
GLU
0.69
0.33
0.62
3
70
A
ASP
0.27
0.32
0.63
5
73
A
ARG
0.43
0.51
0.51
10
74
A
GLN
0.22
0.43
0.57
10
77
A
ARG
0.46
0.51
0.51
10
78
A
GLU
0.39
0.33
0.59
10
79
A
LEU
0.71
0.70
0.54
10
80
A
ASP
0.49
0.32
0.58
1
81
A
LEU
0.32
0.70
0.40
2
85
A
ILE
0.16
0.64
0.45
10
1
A
GLY
0.00
0.41
0.84
10
2
A
SER
0.91
0.36
0.85
10
3
A
ARG
1.00
0.51
0.90
10
4
A
ILE
0.65
0.64
0.81
10
5
A
ALA
0.79
0.38
0.85
10
6
A
LYS
0.68
0.25
0.76
10
7
A
ARG
0.55
0.51
0.69
10
8
A
THR
0.33
0.33
0.72
6
9
A
ALA
0.53
0.38
0.64
9
10
A
ILE
0.65
0.64
0.62
10
13
A
THR
0.53
0.33
0.55
10
14
A
LYS
0.76
0.25
0.67
10
15
A
LYS
0.32
0.25
0.69
10
17
A
ASP
1.00
0.32
0.40
4
18
A
VAL
0.79
0.56
0.52
10
22
A
ALA
0.82
0.38
0.40
2
27
A
ILE
0.46
0.64
0.52
2
33
A
LEU
0.30
0.70
0.68
5
34
A
GLU
0.29
0.33
0.66
9
36
A
LEU
0.70
0.70
0.47
10
37
A
GLN
0.40
0.43
0.70
10
38
A
GLN
0.31
0.43
0.68
10
39
A
ILE
0.91
0.64
0.42
10
40
A
ALA
0.67
0.38
0.53
10
41
A
GLN
0.51
0.43
0.68
10
42
A
LYS
0.52
0.25
0.60
9
43
A
PRO
0.76
0.47
0.49
10
44
A
GLY
1.00
0.41
0.55
10
45
A
ALA
0.74
0.38
0.44
10
46
A
LEU
0.82
0.70
0.27
10
47
A
ARG
0.97
0.51
0.56
10
48
A
ILE
0.45
0.64
0.51
10
49
A
LEU
0.62
0.70
0.27
10
50
A
ASN
0.42
0.39
0.30
1
51
A
HIS
0.48
0.60
0.46
10
54
A
ARG
0.60
0.51
0.44
10
56
A
ALA
1.00
0.38
0.19
8
57
A
ALA
0.45
0.38
0.45
9
58
A
MET
0.67
0.66
0.53
9
59
A
THR
0.36
0.33
0.64
9
60
A
ALA
1.00
0.38
0.70
9
61
A
HIS
0.33
0.60
0.59
9
62
A
GLY
0.81
0.41
0.74
9
63
A
LYS
0.29
0.25
0.74
1
64
A
GLY
0.62
0.41
0.63
9
65
A
GLU
0.08
0.33
0.62
9
66
A
ARG
0.37
0.51
0.73
7
69
A
GLU
0.69
0.33
0.63
2
73
A
ARG
0.43
0.51
0.51
9
74
A
GLN
0.22
0.43
0.58
7
77
A
ARG
0.46
0.51
0.51
9
78
A
GLU
0.39
0.33
0.61
7
79
A
LEU
0.71
0.70
0.57
7
80
A
ASP
0.49
0.32
0.62
2
81
A
LEU
0.32
0.70
0.44
3
82
A
ASP
0.53
0.32
0.67
2
83
A
VAL
0.49
0.56
0.74
2
85
A
ILE
0.16
0.64
0.48
9
86
A
SER
0.37
0.36
0.65
2
87
A
THR
0.18
0.33
0.75
2
89
A
LEU
0.42
0.70
0.73
1
90
A
ARG
0.23
0.51
0.83
1
1
A
GLY
0.00
0.41
0.89
10
2
A
SER
0.91
0.36
0.87
10
3
A
ARG
1.00
0.51
0.88
10
4
A
ILE
0.65
0.64
0.81
10
5
A
ALA
0.79
0.38
0.79
10
6
A
LYS
0.68
0.25
0.79
10
7
A
ARG
0.55
0.51
0.66
9
8
A
THR
0.33
0.33
0.72
7
9
A
ALA
0.53
0.38
0.66
10
10
A
ILE
0.65
0.64
0.65
10
13
A
THR
0.53
0.33
0.57
9
14
A
LYS
0.76
0.25
0.67
10
15
A
LYS
0.32
0.25
0.71
10
17
A
ASP
1.00
0.32
0.40
7
18
A
VAL
0.79
0.56
0.50
10
22
A
ALA
0.82
0.38
0.44
3
25
A
TRP
1.00
0.99
0.18
10
26
A
GLN
0.35
0.43
0.58
10
27
A
ILE
0.46
0.64
0.54
7
28
A
ASN
0.26
0.39
0.72
6
29
A
GLY
0.56
0.41
0.70
6
30
A
GLU
0.37
0.33
0.78
2
31
A
LYS
0.23
0.25
0.73
2
32
A
GLU
0.74
0.33
0.53
1
33
A
LEU
0.30
0.70
0.70
6
34
A
GLU
0.29
0.33
0.69
10
35
A
LEU
0.59
0.70
0.44
10
36
A
LEU
0.70
0.70
0.50
10
37
A
GLN
0.40
0.43
0.72
10
38
A
GLN
0.31
0.43
0.70
10
39
A
ILE
0.91
0.64
0.46
9
40
A
ALA
0.67
0.38
0.55
10
41
A
GLN
0.51
0.43
0.71
10
42
A
LYS
0.52
0.25
0.64
10
43
A
PRO
0.76
0.47
0.52
10
44
A
GLY
1.00
0.41
0.57
10
45
A
ALA
0.74
0.38
0.43
9
46
A
LEU
0.82
0.70
0.27
10
47
A
ARG
0.97
0.51
0.54
10
48
A
ILE
0.45
0.64
0.48
10
49
A
LEU
0.62
0.70
0.26
10
51
A
HIS
0.48
0.60
0.45
10
54
A
ARG
0.60
0.51
0.45
10
56
A
ALA
1.00
0.38
0.22
10
57
A
ALA
0.45
0.38
0.47
10
58
A
MET
0.67
0.66
0.53
10
59
A
THR
0.36
0.33
0.65
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.61
10
62
A
GLY
0.81
0.41
0.76
10
63
A
LYS
0.29
0.25
0.78
10
64
A
GLY
0.62
0.41
0.67
10
65
A
GLU
0.08
0.33
0.65
10
66
A
ARG
0.37
0.51
0.74
10
67
A
VAL
0.55
0.56
0.75
1
68
A
ASN
0.27
0.39
0.70
1
69
A
GLU
0.69
0.33
0.63
1
70
A
ASP
0.27
0.32
0.63
3
73
A
ARG
0.43
0.51
0.51
10
74
A
GLN
0.22
0.43
0.58
10
77
A
ARG
0.46
0.51
0.51
10
79
A
LEU
0.71
0.70
0.56
10
80
A
ASP
0.49
0.32
0.61
1
81
A
LEU
0.32
0.70
0.44
2
82
A
ASP
0.53
0.32
0.66
1
83
A
VAL
0.49
0.56
0.72
1
85
A
ILE
0.16
0.64
0.47
10
87
A
THR
0.18
0.33
0.70
10
88
A
LEU
0.34
0.70
0.77
1
89
A
LEU
0.42
0.70
0.77
3
1
A
GLY
0.00
0.41
0.79
10
2
A
SER
0.91
0.36
0.81
10
3
A
ARG
1.00
0.51
0.73
10
4
A
ILE
0.65
0.64
0.85
10
5
A
ALA
0.79
0.38
0.76
10
6
A
LYS
0.68
0.25
0.82
10
7
A
ARG
0.55
0.51
0.76
10
8
A
THR
0.33
0.33
0.78
10
9
A
ALA
0.53
0.38
0.67
10
10
A
ILE
0.65
0.64
0.66
10
13
A
THR
0.53
0.33
0.63
9
14
A
LYS
0.76
0.25
0.71
10
15
A
LYS
0.32
0.25
0.74
10
17
A
ASP
1.00
0.32
0.47
8
18
A
VAL
0.79
0.56
0.54
10
22
A
ALA
0.82
0.38
0.44
4
26
A
GLN
0.35
0.43
0.54
7
28
A
ASN
0.26
0.39
0.71
1
33
A
LEU
0.30
0.70
0.67
2
34
A
GLU
0.29
0.33
0.68
2
35
A
LEU
0.59
0.70
0.43
10
36
A
LEU
0.70
0.70
0.44
8
37
A
GLN
0.40
0.43
0.70
8
38
A
GLN
0.31
0.43
0.69
10
40
A
ALA
0.67
0.38
0.47
7
41
A
GLN
0.51
0.43
0.65
10
42
A
LYS
0.52
0.25
0.62
9
43
A
PRO
0.76
0.47
0.48
10
44
A
GLY
1.00
0.41
0.56
10
45
A
ALA
0.74
0.38
0.50
10
46
A
LEU
0.82
0.70
0.27
10
47
A
ARG
0.97
0.51
0.56
10
48
A
ILE
0.45
0.64
0.54
10
49
A
LEU
0.62
0.70
0.31
10
51
A
HIS
0.48
0.60
0.45
10
54
A
ARG
0.60
0.51
0.40
9
56
A
ALA
1.00
0.38
0.15
7
57
A
ALA
0.45
0.38
0.42
7
58
A
MET
0.67
0.66
0.49
7
59
A
THR
0.36
0.33
0.61
7
60
A
ALA
1.00
0.38
0.68
7
61
A
HIS
0.33
0.60
0.59
7
62
A
GLY
0.81
0.41
0.74
7
64
A
GLY
0.62
0.41
0.64
7
65
A
GLU
0.08
0.33
0.61
7
66
A
ARG
0.37
0.51
0.73
2
67
A
VAL
0.55
0.56
0.72
1
68
A
ASN
0.27
0.39
0.69
1
69
A
GLU
0.69
0.33
0.62
1
70
A
ASP
0.27
0.32
0.64
2
73
A
ARG
0.43
0.51
0.53
10
74
A
GLN
0.22
0.43
0.59
4
76
A
PHE
0.40
1.00
0.25
10
77
A
ARG
0.46
0.51
0.57
1
78
A
GLU
0.39
0.33
0.63
3
79
A
LEU
0.71
0.70
0.58
2
80
A
ASP
0.49
0.32
0.64
2
81
A
LEU
0.32
0.70
0.47
3
82
A
ASP
0.53
0.32
0.67
2
83
A
VAL
0.49
0.56
0.73
2
85
A
ILE
0.16
0.64
0.47
2
87
A
THR
0.18
0.33
0.68
7
88
A
LEU
0.34
0.70
0.77
1
89
A
LEU
0.42
0.70
0.77
1
1
A
GLY
0.00
0.41
0.85
10
2
A
SER
0.91
0.36
0.89
10
3
A
ARG
1.00
0.51
0.88
10
4
A
ILE
0.65
0.64
0.79
10
5
A
ALA
0.79
0.38
0.73
10
6
A
LYS
0.68
0.25
0.82
10
7
A
ARG
0.55
0.51
0.73
10
8
A
THR
0.33
0.33
0.73
10
9
A
ALA
0.53
0.38
0.63
10
10
A
ILE
0.65
0.64
0.65
10
12
A
LYS
0.64
0.25
0.23
2
13
A
THR
0.53
0.33
0.59
10
14
A
LYS
0.76
0.25
0.68
10
15
A
LYS
0.32
0.25
0.75
10
16
A
ALA
0.26
0.38
0.56
2
17
A
ASP
1.00
0.32
0.45
10
18
A
VAL
0.79
0.56
0.54
10
22
A
ALA
0.82
0.38
0.44
2
25
A
TRP
1.00
0.99
0.15
10
26
A
GLN
0.35
0.43
0.55
10
27
A
ILE
0.46
0.64
0.52
9
28
A
ASN
0.26
0.39
0.70
8
29
A
GLY
0.56
0.41
0.67
8
30
A
GLU
0.37
0.33
0.77
1
31
A
LYS
0.23
0.25
0.71
1
33
A
LEU
0.30
0.70
0.67
1
34
A
GLU
0.29
0.33
0.68
4
35
A
LEU
0.59
0.70
0.43
10
36
A
LEU
0.70
0.70
0.44
10
37
A
GLN
0.40
0.43
0.69
6
38
A
GLN
0.31
0.43
0.66
8
39
A
ILE
0.91
0.64
0.41
4
40
A
ALA
0.67
0.38
0.47
6
41
A
GLN
0.51
0.43
0.63
4
42
A
LYS
0.52
0.25
0.60
7
43
A
PRO
0.76
0.47
0.46
10
44
A
GLY
1.00
0.41
0.54
10
45
A
ALA
0.74
0.38
0.47
10
46
A
LEU
0.82
0.70
0.25
10
47
A
ARG
0.97
0.51
0.54
10
48
A
ILE
0.45
0.64
0.52
10
49
A
LEU
0.62
0.70
0.29
10
50
A
ASN
0.42
0.39
0.28
1
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.43
10
56
A
ALA
1.00
0.38
0.17
10
57
A
ALA
0.45
0.38
0.43
10
58
A
MET
0.67
0.66
0.52
10
59
A
THR
0.36
0.33
0.63
10
60
A
ALA
1.00
0.38
0.68
10
61
A
HIS
0.33
0.60
0.58
10
62
A
GLY
0.81
0.41
0.74
10
63
A
LYS
0.29
0.25
0.75
10
64
A
GLY
0.62
0.41
0.67
10
65
A
GLU
0.08
0.33
0.64
10
66
A
ARG
0.37
0.51
0.73
10
67
A
VAL
0.55
0.56
0.75
2
68
A
ASN
0.27
0.39
0.70
2
70
A
ASP
0.27
0.32
0.64
3
71
A
TYR
0.50
0.80
0.48
10
73
A
ARG
0.43
0.51
0.56
10
74
A
GLN
0.22
0.43
0.59
10
76
A
PHE
0.40
1.00
0.24
10
77
A
ARG
0.46
0.51
0.56
8
79
A
LEU
0.71
0.70
0.58
10
80
A
ASP
0.49
0.32
0.62
3
81
A
LEU
0.32
0.70
0.45
4
85
A
ILE
0.16
0.64
0.47
10
1
A
GLY
0.00
0.41
0.92
10
2
A
SER
0.91
0.36
0.88
10
3
A
ARG
1.00
0.51
0.89
10
4
A
ILE
0.65
0.64
0.80
10
5
A
ALA
0.79
0.38
0.73
10
6
A
LYS
0.68
0.25
0.80
10
7
A
ARG
0.55
0.51
0.71
10
8
A
THR
0.33
0.33
0.73
7
9
A
ALA
0.53
0.38
0.66
10
10
A
ILE
0.65
0.64
0.62
10
13
A
THR
0.53
0.33
0.57
9
14
A
LYS
0.76
0.25
0.60
10
15
A
LYS
0.32
0.25
0.71
10
17
A
ASP
1.00
0.32
0.40
10
18
A
VAL
0.79
0.56
0.51
10
22
A
ALA
0.82
0.38
0.43
5
24
A
ALA
1.00
0.38
0.27
3
27
A
ILE
0.46
0.64
0.54
6
31
A
LYS
0.23
0.25
0.74
7
33
A
LEU
0.30
0.70
0.71
7
34
A
GLU
0.29
0.33
0.70
9
35
A
LEU
0.59
0.70
0.46
10
36
A
LEU
0.70
0.70
0.51
10
37
A
GLN
0.40
0.43
0.73
10
38
A
GLN
0.31
0.43
0.71
10
39
A
ILE
0.91
0.64
0.46
10
40
A
ALA
0.67
0.38
0.56
10
41
A
GLN
0.51
0.43
0.71
10
42
A
LYS
0.52
0.25
0.64
9
43
A
PRO
0.76
0.47
0.53
10
44
A
GLY
1.00
0.41
0.59
10
45
A
ALA
0.74
0.38
0.47
10
46
A
LEU
0.82
0.70
0.31
10
47
A
ARG
0.97
0.51
0.54
10
48
A
ILE
0.45
0.64
0.47
10
49
A
LEU
0.62
0.70
0.24
10
50
A
ASN
0.42
0.39
0.30
1
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.45
10
56
A
ALA
1.00
0.38
0.22
9
57
A
ALA
0.45
0.38
0.48
9
58
A
MET
0.67
0.66
0.54
9
59
A
THR
0.36
0.33
0.65
9
60
A
ALA
1.00
0.38
0.71
9
61
A
HIS
0.33
0.60
0.59
9
62
A
GLY
0.81
0.41
0.74
9
63
A
LYS
0.29
0.25
0.73
2
65
A
GLU
0.08
0.33
0.63
9
73
A
ARG
0.43
0.51
0.53
10
76
A
PHE
0.40
1.00
0.20
10
79
A
LEU
0.71
0.70
0.54
2
80
A
ASP
0.49
0.32
0.59
1
81
A
LEU
0.32
0.70
0.41
1
82
A
ASP
0.53
0.32
0.63
1
83
A
VAL
0.49
0.56
0.71
1
85
A
ILE
0.16
0.64
0.46
9
87
A
THR
0.18
0.33
0.74
1
89
A
LEU
0.42
0.70
0.73
9
1
A
GLY
0.00
0.41
0.76
10
2
A
SER
0.91
0.36
0.76
10
3
A
ARG
1.00
0.51
0.78
10
4
A
ILE
0.65
0.64
0.80
10
5
A
ALA
0.79
0.38
0.80
10
6
A
LYS
0.68
0.25
0.72
10
7
A
ARG
0.55
0.51
0.82
10
8
A
THR
0.33
0.33
0.74
9
9
A
ALA
0.53
0.38
0.68
10
10
A
ILE
0.65
0.64
0.66
10
13
A
THR
0.53
0.33
0.63
9
14
A
LYS
0.76
0.25
0.72
10
15
A
LYS
0.32
0.25
0.76
9
17
A
ASP
1.00
0.32
0.46
9
18
A
VAL
0.79
0.56
0.55
9
22
A
ALA
0.82
0.38
0.45
2
25
A
TRP
1.00
0.99
0.16
9
26
A
GLN
0.35
0.43
0.56
8
27
A
ILE
0.46
0.64
0.54
5
28
A
ASN
0.26
0.39
0.72
3
29
A
GLY
0.56
0.41
0.69
3
30
A
GLU
0.37
0.33
0.79
1
33
A
LEU
0.30
0.70
0.69
4
35
A
LEU
0.59
0.70
0.47
8
36
A
LEU
0.70
0.70
0.47
10
37
A
GLN
0.40
0.43
0.72
8
38
A
GLN
0.31
0.43
0.71
8
39
A
ILE
0.91
0.64
0.46
10
40
A
ALA
0.67
0.38
0.50
6
41
A
GLN
0.51
0.43
0.67
10
42
A
LYS
0.52
0.25
0.66
3
43
A
PRO
0.76
0.47
0.51
10
44
A
GLY
1.00
0.41
0.59
10
45
A
ALA
0.74
0.38
0.51
9
46
A
LEU
0.82
0.70
0.28
10
47
A
ARG
0.97
0.51
0.56
10
48
A
ILE
0.45
0.64
0.53
10
49
A
LEU
0.62
0.70
0.30
10
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.41
8
56
A
ALA
1.00
0.38
0.18
8
57
A
ALA
0.45
0.38
0.44
8
58
A
MET
0.67
0.66
0.51
8
59
A
THR
0.36
0.33
0.60
8
60
A
ALA
1.00
0.38
0.67
8
61
A
HIS
0.33
0.60
0.57
8
62
A
GLY
0.81
0.41
0.73
8
64
A
GLY
0.62
0.41
0.67
8
66
A
ARG
0.37
0.51
0.73
7
67
A
VAL
0.55
0.56
0.74
1
68
A
ASN
0.27
0.39
0.70
1
69
A
GLU
0.69
0.33
0.65
2
70
A
ASP
0.27
0.32
0.63
2
73
A
ARG
0.43
0.51
0.55
9
74
A
GLN
0.22
0.43
0.58
7
76
A
PHE
0.40
1.00
0.22
9
77
A
ARG
0.46
0.51
0.55
3
79
A
LEU
0.71
0.70
0.56
7
80
A
ASP
0.49
0.32
0.62
1
81
A
LEU
0.32
0.70
0.44
2
82
A
ASP
0.53
0.32
0.66
1
83
A
VAL
0.49
0.56
0.72
1
85
A
ILE
0.16
0.64
0.46
8
87
A
THR
0.18
0.33
0.70
8
1
A
GLY
0.00
0.41
0.86
10
2
A
SER
0.91
0.36
0.86
10
3
A
ARG
1.00
0.51
0.91
10
4
A
ILE
0.65
0.64
0.81
10
5
A
ALA
0.79
0.38
0.81
10
6
A
LYS
0.68
0.25
0.78
10
7
A
ARG
0.55
0.51
0.65
10
8
A
THR
0.33
0.33
0.71
5
9
A
ALA
0.53
0.38
0.65
9
10
A
ILE
0.65
0.64
0.65
10
12
A
LYS
0.64
0.25
0.22
1
13
A
THR
0.53
0.33
0.57
3
14
A
LYS
0.76
0.25
0.62
3
15
A
LYS
0.32
0.25
0.69
4
17
A
ASP
1.00
0.32
0.38
2
18
A
VAL
0.79
0.56
0.51
4
22
A
ALA
0.82
0.38
0.43
2
24
A
ALA
1.00
0.38
0.26
1
25
A
TRP
1.00
0.99
0.18
10
26
A
GLN
0.35
0.43
0.58
9
27
A
ILE
0.46
0.64
0.53
6
28
A
ASN
0.26
0.39
0.72
4
29
A
GLY
0.56
0.41
0.70
4
30
A
GLU
0.37
0.33
0.79
1
33
A
LEU
0.30
0.70
0.71
3
34
A
GLU
0.29
0.33
0.71
8
35
A
LEU
0.59
0.70
0.47
10
36
A
LEU
0.70
0.70
0.52
10
37
A
GLN
0.40
0.43
0.74
10
38
A
GLN
0.31
0.43
0.72
10
39
A
ILE
0.91
0.64
0.47
10
40
A
ALA
0.67
0.38
0.57
10
41
A
GLN
0.51
0.43
0.71
10
42
A
LYS
0.52
0.25
0.65
10
43
A
PRO
0.76
0.47
0.52
10
44
A
GLY
1.00
0.41
0.55
10
45
A
ALA
0.74
0.38
0.42
8
46
A
LEU
0.82
0.70
0.28
10
47
A
ARG
0.97
0.51
0.54
10
48
A
ILE
0.45
0.64
0.46
10
49
A
LEU
0.62
0.70
0.24
10
50
A
ASN
0.42
0.39
0.30
2
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.47
9
56
A
ALA
1.00
0.38
0.24
8
57
A
ALA
0.45
0.38
0.49
9
58
A
MET
0.67
0.66
0.54
9
59
A
THR
0.36
0.33
0.66
9
60
A
ALA
1.00
0.38
0.72
9
61
A
HIS
0.33
0.60
0.61
9
62
A
GLY
0.81
0.41
0.76
9
63
A
LYS
0.29
0.25
0.75
9
64
A
GLY
0.62
0.41
0.66
9
65
A
GLU
0.08
0.33
0.62
9
66
A
ARG
0.37
0.51
0.73
7
67
A
VAL
0.55
0.56
0.74
1
68
A
ASN
0.27
0.39
0.71
1
70
A
ASP
0.27
0.32
0.63
2
71
A
TYR
0.50
0.80
0.49
9
73
A
ARG
0.43
0.51
0.52
7
74
A
GLN
0.22
0.43
0.58
7
77
A
ARG
0.46
0.51
0.52
7
79
A
LEU
0.71
0.70
0.56
8
80
A
ASP
0.49
0.32
0.60
2
81
A
LEU
0.32
0.70
0.42
2
82
A
ASP
0.53
0.32
0.65
2
83
A
VAL
0.49
0.56
0.71
2
85
A
ILE
0.16
0.64
0.47
9
87
A
THR
0.18
0.33
0.72
2
88
A
LEU
0.34
0.70
0.76
2
89
A
LEU
0.42
0.70
0.76
6
1
A
GLY
0.00
0.41
0.88
10
2
A
SER
0.91
0.36
0.82
10
3
A
ARG
1.00
0.51
0.85
10
4
A
ILE
0.65
0.64
0.79
10
5
A
ALA
0.79
0.38
0.78
10
6
A
LYS
0.68
0.25
0.77
10
7
A
ARG
0.55
0.51
0.69
10
8
A
THR
0.33
0.33
0.78
10
9
A
ALA
0.53
0.38
0.67
10
10
A
ILE
0.65
0.64
0.65
10
13
A
THR
0.53
0.33
0.57
3
14
A
LYS
0.76
0.25
0.66
10
15
A
LYS
0.32
0.25
0.73
10
17
A
ASP
1.00
0.32
0.41
5
18
A
VAL
0.79
0.56
0.51
10
25
A
TRP
1.00
0.99
0.19
9
26
A
GLN
0.35
0.43
0.58
9
27
A
ILE
0.46
0.64
0.55
5
28
A
ASN
0.26
0.39
0.73
5
29
A
GLY
0.56
0.41
0.71
5
30
A
GLU
0.37
0.33
0.80
1
33
A
LEU
0.30
0.70
0.72
1
35
A
LEU
0.59
0.70
0.47
10
36
A
LEU
0.70
0.70
0.53
10
37
A
GLN
0.40
0.43
0.74
10
38
A
GLN
0.31
0.43
0.72
10
39
A
ILE
0.91
0.64
0.47
6
40
A
ALA
0.67
0.38
0.57
10
41
A
GLN
0.51
0.43
0.72
10
42
A
LYS
0.52
0.25
0.66
10
43
A
PRO
0.76
0.47
0.52
10
44
A
GLY
1.00
0.41
0.58
10
45
A
ALA
0.74
0.38
0.45
7
46
A
LEU
0.82
0.70
0.29
10
47
A
ARG
0.97
0.51
0.54
10
48
A
ILE
0.45
0.64
0.46
10
49
A
LEU
0.62
0.70
0.24
10
51
A
HIS
0.48
0.60
0.43
10
54
A
ARG
0.60
0.51
0.45
10
56
A
ALA
1.00
0.38
0.24
9
57
A
ALA
0.45
0.38
0.49
9
58
A
MET
0.67
0.66
0.54
9
59
A
THR
0.36
0.33
0.67
9
60
A
ALA
1.00
0.38
0.71
9
61
A
HIS
0.33
0.60
0.60
9
62
A
GLY
0.81
0.41
0.75
9
63
A
LYS
0.29
0.25
0.74
9
64
A
GLY
0.62
0.41
0.66
9
65
A
GLU
0.08
0.33
0.65
9
66
A
ARG
0.37
0.51
0.72
7
67
A
VAL
0.55
0.56
0.76
1
68
A
ASN
0.27
0.39
0.71
1
69
A
GLU
0.69
0.33
0.64
1
70
A
ASP
0.27
0.32
0.63
1
71
A
TYR
0.50
0.80
0.49
9
73
A
ARG
0.43
0.51
0.51
10
74
A
GLN
0.22
0.43
0.59
7
77
A
ARG
0.46
0.51
0.54
10
79
A
LEU
0.71
0.70
0.56
7
80
A
ASP
0.49
0.32
0.60
2
81
A
LEU
0.32
0.70
0.42
2
82
A
ASP
0.53
0.32
0.65
2
83
A
VAL
0.49
0.56
0.71
2
85
A
ILE
0.16
0.64
0.46
9
87
A
THR
0.18
0.33
0.70
2
88
A
LEU
0.34
0.70
0.75
2
1
A
GLY
0.00
0.41
0.92
10
2
A
SER
0.91
0.36
0.90
10
3
A
ARG
1.00
0.51
0.85
10
4
A
ILE
0.65
0.64
0.85
10
5
A
ALA
0.79
0.38
0.82
10
6
A
LYS
0.68
0.25
0.76
10
7
A
ARG
0.55
0.51
0.58
8
8
A
THR
0.33
0.33
0.71
6
9
A
ALA
0.53
0.38
0.63
10
10
A
ILE
0.65
0.64
0.60
10
13
A
THR
0.53
0.33
0.53
3
14
A
LYS
0.76
0.25
0.64
10
15
A
LYS
0.32
0.25
0.70
10
17
A
ASP
1.00
0.32
0.38
5
18
A
VAL
0.79
0.56
0.49
10
22
A
ALA
0.82
0.38
0.40
3
26
A
GLN
0.35
0.43
0.55
8
35
A
LEU
0.59
0.70
0.44
8
36
A
LEU
0.70
0.70
0.47
8
37
A
GLN
0.40
0.43
0.71
8
38
A
GLN
0.31
0.43
0.69
10
40
A
ALA
0.67
0.38
0.52
10
41
A
GLN
0.51
0.43
0.68
10
42
A
LYS
0.52
0.25
0.63
10
43
A
PRO
0.76
0.47
0.53
10
44
A
GLY
1.00
0.41
0.56
10
45
A
ALA
0.74
0.38
0.50
10
46
A
LEU
0.82
0.70
0.32
10
47
A
ARG
0.97
0.51
0.57
10
48
A
ILE
0.45
0.64
0.50
10
49
A
LEU
0.62
0.70
0.26
10
51
A
HIS
0.48
0.60
0.46
10
54
A
ARG
0.60
0.51
0.46
10
56
A
ALA
1.00
0.38
0.20
7
57
A
ALA
0.45
0.38
0.47
8
58
A
MET
0.67
0.66
0.52
8
59
A
THR
0.36
0.33
0.65
8
60
A
ALA
1.00
0.38
0.71
8
61
A
HIS
0.33
0.60
0.61
8
62
A
GLY
0.81
0.41
0.75
8
63
A
LYS
0.29
0.25
0.74
8
65
A
GLU
0.08
0.33
0.63
8
73
A
ARG
0.43
0.51
0.50
8
77
A
ARG
0.46
0.51
0.52
8
80
A
ASP
0.49
0.32
0.62
1
81
A
LEU
0.32
0.70
0.44
2
82
A
ASP
0.53
0.32
0.67
1
83
A
VAL
0.49
0.56
0.73
1
85
A
ILE
0.16
0.64
0.48
8
86
A
SER
0.37
0.36
0.65
1
87
A
THR
0.18
0.33
0.72
1
90
A
ARG
0.23
0.51
0.80
8
1
A
GLY
0.00
0.41
0.91
10
2
A
SER
0.91
0.36
0.85
10
3
A
ARG
1.00
0.51
0.83
10
4
A
ILE
0.65
0.64
0.83
10
5
A
ALA
0.79
0.38
0.76
10
6
A
LYS
0.68
0.25
0.72
10
7
A
ARG
0.55
0.51
0.73
10
8
A
THR
0.33
0.33
0.73
10
9
A
ALA
0.53
0.38
0.67
10
10
A
ILE
0.65
0.64
0.63
10
13
A
THR
0.53
0.33
0.49
2
14
A
LYS
0.76
0.25
0.55
10
15
A
LYS
0.32
0.25
0.67
5
17
A
ASP
1.00
0.32
0.32
8
18
A
VAL
0.79
0.56
0.47
10
22
A
ALA
0.82
0.38
0.39
6
24
A
ALA
1.00
0.38
0.25
2
25
A
TRP
1.00
0.99
0.15
10
26
A
GLN
0.35
0.43
0.57
10
27
A
ILE
0.46
0.64
0.52
10
28
A
ASN
0.26
0.39
0.71
7
29
A
GLY
0.56
0.41
0.68
7
30
A
GLU
0.37
0.33
0.77
2
32
A
GLU
0.74
0.33
0.51
1
33
A
LEU
0.30
0.70
0.68
8
36
A
LEU
0.70
0.70
0.52
9
37
A
GLN
0.40
0.43
0.72
9
38
A
GLN
0.31
0.43
0.71
9
39
A
ILE
0.91
0.64
0.47
10
40
A
ALA
0.67
0.38
0.58
10
41
A
GLN
0.51
0.43
0.72
10
42
A
LYS
0.52
0.25
0.62
4
43
A
PRO
0.76
0.47
0.54
10
44
A
GLY
1.00
0.41
0.59
10
45
A
ALA
0.74
0.38
0.45
10
46
A
LEU
0.82
0.70
0.33
10
47
A
ARG
0.97
0.51
0.57
10
48
A
ILE
0.45
0.64
0.48
10
49
A
LEU
0.62
0.70
0.23
10
51
A
HIS
0.48
0.60
0.45
10
53
A
LEU
0.90
0.70
0.00
7
54
A
ARG
0.60
0.51
0.48
10
56
A
ALA
1.00
0.38
0.23
10
57
A
ALA
0.45
0.38
0.49
10
58
A
MET
0.67
0.66
0.54
10
59
A
THR
0.36
0.33
0.65
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.60
10
62
A
GLY
0.81
0.41
0.75
10
64
A
GLY
0.62
0.41
0.66
10
65
A
GLU
0.08
0.33
0.64
10
66
A
ARG
0.37
0.51
0.71
7
67
A
VAL
0.55
0.56
0.74
4
68
A
ASN
0.27
0.39
0.68
4
69
A
GLU
0.69
0.33
0.61
7
70
A
ASP
0.27
0.32
0.60
7
71
A
TYR
0.50
0.80
0.47
10
73
A
ARG
0.43
0.51
0.48
10
74
A
GLN
0.22
0.43
0.56
9
77
A
ARG
0.46
0.51
0.49
10
79
A
LEU
0.71
0.70
0.57
7
81
A
LEU
0.32
0.70
0.40
7
85
A
ILE
0.16
0.64
0.47
10
1
A
GLY
0.00
0.41
0.92
10
2
A
SER
0.91
0.36
0.90
10
3
A
ARG
1.00
0.51
0.88
10
4
A
ILE
0.65
0.64
0.86
10
5
A
ALA
0.79
0.38
0.78
10
6
A
LYS
0.68
0.25
0.75
10
7
A
ARG
0.55
0.51
0.63
8
8
A
THR
0.33
0.33
0.72
1
9
A
ALA
0.53
0.38
0.65
8
10
A
ILE
0.65
0.64
0.67
10
13
A
THR
0.53
0.33
0.57
6
14
A
LYS
0.76
0.25
0.61
5
15
A
LYS
0.32
0.25
0.70
6
17
A
ASP
1.00
0.32
0.38
5
18
A
VAL
0.79
0.56
0.48
6
22
A
ALA
0.82
0.38
0.42
1
25
A
TRP
1.00
0.99
0.17
9
26
A
GLN
0.35
0.43
0.57
9
27
A
ILE
0.46
0.64
0.53
7
28
A
ASN
0.26
0.39
0.71
7
29
A
GLY
0.56
0.41
0.70
7
30
A
GLU
0.37
0.33
0.78
1
31
A
LYS
0.23
0.25
0.73
1
33
A
LEU
0.30
0.70
0.69
3
34
A
GLU
0.29
0.33
0.69
5
35
A
LEU
0.59
0.70
0.45
10
36
A
LEU
0.70
0.70
0.44
10
37
A
GLN
0.40
0.43
0.70
10
38
A
GLN
0.31
0.43
0.69
10
39
A
ILE
0.91
0.64
0.43
10
40
A
ALA
0.67
0.38
0.49
8
41
A
GLN
0.51
0.43
0.66
10
42
A
LYS
0.52
0.25
0.63
10
43
A
PRO
0.76
0.47
0.52
10
44
A
GLY
1.00
0.41
0.55
10
45
A
ALA
0.74
0.38
0.50
10
46
A
LEU
0.82
0.70
0.31
10
47
A
ARG
0.97
0.51
0.56
10
48
A
ILE
0.45
0.64
0.47
10
49
A
LEU
0.62
0.70
0.24
10
51
A
HIS
0.48
0.60
0.44
10
53
A
LEU
0.90
0.70
0.00
4
54
A
ARG
0.60
0.51
0.47
9
56
A
ALA
1.00
0.38
0.24
9
57
A
ALA
0.45
0.38
0.49
9
58
A
MET
0.67
0.66
0.54
9
59
A
THR
0.36
0.33
0.66
9
60
A
ALA
1.00
0.38
0.71
9
61
A
HIS
0.33
0.60
0.60
9
62
A
GLY
0.81
0.41
0.76
9
63
A
LYS
0.29
0.25
0.75
1
64
A
GLY
0.62
0.41
0.66
9
65
A
GLU
0.08
0.33
0.65
9
66
A
ARG
0.37
0.51
0.73
8
70
A
ASP
0.27
0.32
0.61
1
73
A
ARG
0.43
0.51
0.51
8
74
A
GLN
0.22
0.43
0.58
8
76
A
PHE
0.40
1.00
0.20
9
77
A
ARG
0.46
0.51
0.52
7
78
A
GLU
0.39
0.33
0.60
8
79
A
LEU
0.71
0.70
0.56
8
81
A
LEU
0.32
0.70
0.42
4
85
A
ILE
0.16
0.64
0.47
9
89
A
LEU
0.42
0.70
0.77
1
1
A
GLY
0.00
0.41
0.90
10
2
A
SER
0.91
0.36
0.86
10
3
A
ARG
1.00
0.51
0.80
10
4
A
ILE
0.65
0.64
0.80
10
5
A
ALA
0.79
0.38
0.69
10
6
A
LYS
0.68
0.25
0.78
10
7
A
ARG
0.55
0.51
0.75
10
8
A
THR
0.33
0.33
0.77
9
9
A
ALA
0.53
0.38
0.68
10
10
A
ILE
0.65
0.64
0.67
10
12
A
LYS
0.64
0.25
0.23
2
13
A
THR
0.53
0.33
0.53
5
14
A
LYS
0.76
0.25
0.58
7
15
A
LYS
0.32
0.25
0.71
7
17
A
ASP
1.00
0.32
0.38
5
18
A
VAL
0.79
0.56
0.48
7
22
A
ALA
0.82
0.38
0.44
1
25
A
TRP
1.00
0.99
0.19
10
26
A
GLN
0.35
0.43
0.59
10
27
A
ILE
0.46
0.64
0.55
10
28
A
ASN
0.26
0.39
0.73
8
29
A
GLY
0.56
0.41
0.71
8
30
A
GLU
0.37
0.33
0.80
3
32
A
GLU
0.74
0.33
0.54
1
33
A
LEU
0.30
0.70
0.71
5
35
A
LEU
0.59
0.70
0.46
10
36
A
LEU
0.70
0.70
0.52
10
37
A
GLN
0.40
0.43
0.74
10
38
A
GLN
0.31
0.43
0.73
10
39
A
ILE
0.91
0.64
0.49
7
40
A
ALA
0.67
0.38
0.58
10
41
A
GLN
0.51
0.43
0.73
10
42
A
LYS
0.52
0.25
0.67
10
43
A
PRO
0.76
0.47
0.54
10
44
A
GLY
1.00
0.41
0.56
10
45
A
ALA
0.74
0.38
0.43
8
46
A
LEU
0.82
0.70
0.30
10
47
A
ARG
0.97
0.51
0.55
10
48
A
ILE
0.45
0.64
0.46
10
49
A
LEU
0.62
0.70
0.24
10
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.46
10
56
A
ALA
1.00
0.38
0.25
8
57
A
ALA
0.45
0.38
0.50
10
58
A
MET
0.67
0.66
0.52
10
59
A
THR
0.36
0.33
0.66
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.59
10
62
A
GLY
0.81
0.41
0.74
10
65
A
GLU
0.08
0.33
0.64
10
66
A
ARG
0.37
0.51
0.74
3
67
A
VAL
0.55
0.56
0.75
3
68
A
ASN
0.27
0.39
0.71
5
69
A
GLU
0.69
0.33
0.64
5
70
A
ASP
0.27
0.32
0.62
3
71
A
TYR
0.50
0.80
0.49
10
73
A
ARG
0.43
0.51
0.49
10
74
A
GLN
0.22
0.43
0.57
3
77
A
ARG
0.46
0.51
0.48
10
79
A
LEU
0.71
0.70
0.55
1
80
A
ASP
0.49
0.32
0.59
2
81
A
LEU
0.32
0.70
0.40
4
82
A
ASP
0.53
0.32
0.64
2
83
A
VAL
0.49
0.56
0.71
2
85
A
ILE
0.16
0.64
0.46
10
86
A
SER
0.37
0.36
0.63
2
87
A
THR
0.18
0.33
0.73
2
88
A
LEU
0.34
0.70
0.79
1
89
A
LEU
0.42
0.70
0.76
1
1
A
GLY
0.00
0.41
0.88
10
2
A
SER
0.91
0.36
0.82
10
3
A
ARG
1.00
0.51
0.90
10
4
A
ILE
0.65
0.64
0.80
10
5
A
ALA
0.79
0.38
0.85
10
6
A
LYS
0.68
0.25
0.78
10
7
A
ARG
0.55
0.51
0.78
10
9
A
ALA
0.53
0.38
0.64
10
10
A
ILE
0.65
0.64
0.60
10
13
A
THR
0.53
0.33
0.52
5
14
A
LYS
0.76
0.25
0.56
10
15
A
LYS
0.32
0.25
0.70
3
17
A
ASP
1.00
0.32
0.36
2
18
A
VAL
0.79
0.56
0.49
10
22
A
ALA
0.82
0.38
0.43
3
25
A
TRP
1.00
0.99
0.18
9
26
A
GLN
0.35
0.43
0.59
9
27
A
ILE
0.46
0.64
0.54
7
28
A
ASN
0.26
0.39
0.72
5
29
A
GLY
0.56
0.41
0.70
5
30
A
GLU
0.37
0.33
0.78
2
31
A
LYS
0.23
0.25
0.74
5
33
A
LEU
0.30
0.70
0.69
5
35
A
LEU
0.59
0.70
0.46
10
36
A
LEU
0.70
0.70
0.49
10
37
A
GLN
0.40
0.43
0.72
10
38
A
GLN
0.31
0.43
0.71
10
39
A
ILE
0.91
0.64
0.46
10
40
A
ALA
0.67
0.38
0.54
10
41
A
GLN
0.51
0.43
0.70
10
42
A
LYS
0.52
0.25
0.66
10
43
A
PRO
0.76
0.47
0.56
10
44
A
GLY
1.00
0.41
0.59
10
45
A
ALA
0.74
0.38
0.52
10
46
A
LEU
0.82
0.70
0.33
10
47
A
ARG
0.97
0.51
0.59
10
48
A
ILE
0.45
0.64
0.48
10
49
A
LEU
0.62
0.70
0.24
10
50
A
ASN
0.42
0.39
0.31
2
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.48
10
56
A
ALA
1.00
0.38
0.23
6
57
A
ALA
0.45
0.38
0.49
9
58
A
MET
0.67
0.66
0.53
9
59
A
THR
0.36
0.33
0.66
9
60
A
ALA
1.00
0.38
0.72
9
61
A
HIS
0.33
0.60
0.60
9
62
A
GLY
0.81
0.41
0.75
9
63
A
LYS
0.29
0.25
0.76
2
64
A
GLY
0.62
0.41
0.64
9
66
A
ARG
0.37
0.51
0.74
6
67
A
VAL
0.55
0.56
0.74
2
68
A
ASN
0.27
0.39
0.71
2
69
A
GLU
0.69
0.33
0.64
4
70
A
ASP
0.27
0.32
0.62
4
71
A
TYR
0.50
0.80
0.50
9
73
A
ARG
0.43
0.51
0.50
7
74
A
GLN
0.22
0.43
0.57
6
77
A
ARG
0.46
0.51
0.52
7
79
A
LEU
0.71
0.70
0.57
6
80
A
ASP
0.49
0.32
0.60
2
81
A
LEU
0.32
0.70
0.41
7
90
A
ARG
0.23
0.51
0.77
9
91
A
ASN
0.00
0.39
0.88
2
1
A
GLY
0.00
0.41
0.93
10
2
A
SER
0.91
0.36
0.91
10
3
A
ARG
1.00
0.51
0.87
10
4
A
ILE
0.65
0.64
0.84
10
5
A
ALA
0.79
0.38
0.79
10
6
A
LYS
0.68
0.25
0.74
10
7
A
ARG
0.55
0.51
0.66
4
8
A
THR
0.33
0.33
0.76
9
9
A
ALA
0.53
0.38
0.67
9
10
A
ILE
0.65
0.64
0.66
10
13
A
THR
0.53
0.33
0.59
7
14
A
LYS
0.76
0.25
0.67
10
15
A
LYS
0.32
0.25
0.71
9
17
A
ASP
1.00
0.32
0.41
7
18
A
VAL
0.79
0.56
0.52
9
22
A
ALA
0.82
0.38
0.45
2
24
A
ALA
1.00
0.38
0.28
2
25
A
TRP
1.00
0.99
0.19
10
26
A
GLN
0.35
0.43
0.58
10
27
A
ILE
0.46
0.64
0.55
7
28
A
ASN
0.26
0.39
0.72
6
29
A
GLY
0.56
0.41
0.70
6
30
A
GLU
0.37
0.33
0.79
2
33
A
LEU
0.30
0.70
0.70
3
34
A
GLU
0.29
0.33
0.70
7
35
A
LEU
0.59
0.70
0.45
10
36
A
LEU
0.70
0.70
0.51
10
37
A
GLN
0.40
0.43
0.72
10
38
A
GLN
0.31
0.43
0.70
10
39
A
ILE
0.91
0.64
0.44
7
40
A
ALA
0.67
0.38
0.55
10
41
A
GLN
0.51
0.43
0.69
10
42
A
LYS
0.52
0.25
0.61
7
43
A
PRO
0.76
0.47
0.48
10
44
A
GLY
1.00
0.41
0.55
10
45
A
ALA
0.74
0.38
0.46
10
46
A
LEU
0.82
0.70
0.29
10
47
A
ARG
0.97
0.51
0.53
10
48
A
ILE
0.45
0.64
0.47
10
49
A
LEU
0.62
0.70
0.25
10
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.43
10
56
A
ALA
1.00
0.38
0.23
10
57
A
ALA
0.45
0.38
0.48
10
58
A
MET
0.67
0.66
0.54
10
59
A
THR
0.36
0.33
0.65
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.60
10
62
A
GLY
0.81
0.41
0.74
10
63
A
LYS
0.29
0.25
0.74
1
64
A
GLY
0.62
0.41
0.63
10
65
A
GLU
0.08
0.33
0.63
10
66
A
ARG
0.37
0.51
0.73
8
70
A
ASP
0.27
0.32
0.65
2
73
A
ARG
0.43
0.51
0.53
9
74
A
GLN
0.22
0.43
0.60
8
76
A
PHE
0.40
1.00
0.22
10
77
A
ARG
0.46
0.51
0.54
6
78
A
GLU
0.39
0.33
0.61
9
79
A
LEU
0.71
0.70
0.56
9
89
A
LEU
0.42
0.70
0.73
1
1
A
GLY
0.00
0.41
0.89
10
2
A
SER
0.91
0.36
0.85
10
3
A
ARG
1.00
0.51
0.76
10
4
A
ILE
0.65
0.64
0.77
10
5
A
ALA
0.79
0.38
0.65
10
6
A
LYS
0.68
0.25
0.74
10
7
A
ARG
0.55
0.51
0.75
10
8
A
THR
0.33
0.33
0.78
10
9
A
ALA
0.53
0.38
0.70
10
10
A
ILE
0.65
0.64
0.64
10
13
A
THR
0.53
0.33
0.58
1
15
A
LYS
0.32
0.25
0.70
1
18
A
VAL
0.79
0.56
0.50
3
22
A
ALA
0.82
0.38
0.40
3
24
A
ALA
1.00
0.38
0.25
7
26
A
GLN
0.35
0.43
0.55
1
27
A
ILE
0.46
0.64
0.53
7
28
A
ASN
0.26
0.39
0.72
1
29
A
GLY
0.56
0.41
0.69
1
31
A
LYS
0.23
0.25
0.73
8
33
A
LEU
0.30
0.70
0.71
8
34
A
GLU
0.29
0.33
0.70
8
35
A
LEU
0.59
0.70
0.47
10
36
A
LEU
0.70
0.70
0.51
10
37
A
GLN
0.40
0.43
0.73
10
38
A
GLN
0.31
0.43
0.72
10
40
A
ALA
0.67
0.38
0.56
10
41
A
GLN
0.51
0.43
0.71
10
42
A
LYS
0.52
0.25
0.66
9
43
A
PRO
0.76
0.47
0.50
10
44
A
GLY
1.00
0.41
0.60
10
45
A
ALA
0.74
0.38
0.53
10
46
A
LEU
0.82
0.70
0.33
10
47
A
ARG
0.97
0.51
0.58
10
48
A
ILE
0.45
0.64
0.49
10
49
A
LEU
0.62
0.70
0.25
10
51
A
HIS
0.48
0.60
0.44
10
54
A
ARG
0.60
0.51
0.47
10
56
A
ALA
1.00
0.38
0.22
10
57
A
ALA
0.45
0.38
0.48
10
58
A
MET
0.67
0.66
0.54
10
59
A
THR
0.36
0.33
0.65
10
60
A
ALA
1.00
0.38
0.71
10
61
A
HIS
0.33
0.60
0.59
10
62
A
GLY
0.81
0.41
0.74
10
63
A
LYS
0.29
0.25
0.74
2
64
A
GLY
0.62
0.41
0.63
10
65
A
GLU
0.08
0.33
0.62
10
66
A
ARG
0.37
0.51
0.72
9
67
A
VAL
0.55
0.56
0.72
1
68
A
ASN
0.27
0.39
0.70
1
73
A
ARG
0.43
0.51
0.49
3
74
A
GLN
0.22
0.43
0.57
9
76
A
PHE
0.40
1.00
0.20
10
78
A
GLU
0.39
0.33
0.60
9
79
A
LEU
0.71
0.70
0.55
9
81
A
LEU
0.32
0.70
0.42
1
87
A
THR
0.18
0.33
0.72
10
89
A
LEU
0.42
0.70
0.74
2
1
A
GLY
0.00
0.41
0.92
10
2
A
SER
0.91
0.36
0.87
10
3
A
ARG
1.00
0.51
0.90
10
4
A
ILE
0.65
0.64
0.82
10
5
A
ALA
0.79
0.38
0.83
10
6
A
LYS
0.68
0.25
0.78
10
7
A
ARG
0.55
0.51
0.64
9
8
A
THR
0.33
0.33
0.73
10
9
A
ALA
0.53
0.38
0.62
9
10
A
ILE
0.65
0.64
0.58
10
12
A
LYS
0.64
0.25
0.18
1
13
A
THR
0.53
0.33
0.51
1
14
A
LYS
0.76
0.25
0.60
6
15
A
LYS
0.32
0.25
0.67
6
17
A
ASP
1.00
0.32
0.39
2
18
A
VAL
0.79
0.56
0.47
6
26
A
GLN
0.35
0.43
0.54
10
27
A
ILE
0.46
0.64
0.51
3
28
A
ASN
0.26
0.39
0.70
3
29
A
GLY
0.56
0.41
0.68
2
30
A
GLU
0.37
0.33
0.77
1
31
A
LYS
0.23
0.25
0.71
1
32
A
GLU
0.74
0.33
0.51
1
33
A
LEU
0.30
0.70
0.69
2
34
A
GLU
0.29
0.33
0.69
2
35
A
LEU
0.59
0.70
0.44
9
36
A
LEU
0.70
0.70
0.46
10
37
A
GLN
0.40
0.43
0.71
10
38
A
GLN
0.31
0.43
0.69
10
40
A
ALA
0.67
0.38
0.51
8
41
A
GLN
0.51
0.43
0.68
10
42
A
LYS
0.52
0.25
0.64
10
43
A
PRO
0.76
0.47
0.53
10
44
A
GLY
1.00
0.41
0.58
10
45
A
ALA
0.74
0.38
0.51
10
46
A
LEU
0.82
0.70
0.32
10
47
A
ARG
0.97
0.51
0.57
10
48
A
ILE
0.45
0.64
0.50
10
49
A
LEU
0.62
0.70
0.26
10
50
A
ASN
0.42
0.39
0.31
3
51
A
HIS
0.48
0.60
0.46
10
54
A
ARG
0.60
0.51
0.46
10
56
A
ALA
1.00
0.38
0.20
10
57
A
ALA
0.45
0.38
0.47
10
58
A
MET
0.67
0.66
0.52
10
59
A
THR
0.36
0.33
0.64
10
60
A
ALA
1.00
0.38
0.70
10
61
A
HIS
0.33
0.60
0.58
10
62
A
GLY
0.81
0.41
0.73
10
63
A
LYS
0.29
0.25
0.74
1
65
A
GLU
0.08
0.33
0.61
10
66
A
ARG
0.37
0.51
0.71
1
67
A
VAL
0.55
0.56
0.71
1
68
A
ASN
0.27
0.39
0.69
2
69
A
GLU
0.69
0.33
0.58
1
70
A
ASP
0.27
0.32
0.60
1
71
A
TYR
0.50
0.80
0.46
10
73
A
ARG
0.43
0.51
0.51
1
74
A
GLN
0.22
0.43
0.57
2
76
A
PHE
0.40
1.00
0.20
10
77
A
ARG
0.46
0.51
0.52
2
78
A
GLU
0.39
0.33
0.60
2
79
A
LEU
0.71
0.70
0.56
2
80
A
ASP
0.49
0.32
0.61
4
81
A
LEU
0.32
0.70
0.43
5
82
A
ASP
0.53
0.32
0.65
4
83
A
VAL
0.49
0.56
0.72
4
85
A
ILE
0.16
0.64
0.47
5
86
A
SER
0.37
0.36
0.64
4
87
A
THR
0.18
0.33
0.72
4
89
A
LEU
0.42
0.70
0.76
2
1
A
GLY
0.00
0.41
0.91
10
2
A
SER
0.91
0.36
0.88
10
3
A
ARG
1.00
0.51
0.91
10
4
A
ILE
0.65
0.64
0.85
10
5
A
ALA
0.79
0.38
0.82
10
6
A
LYS
0.68
0.25
0.75
9
7
A
ARG
0.55
0.51
0.64
10
8
A
THR
0.33
0.33
0.70
8
9
A
ALA
0.53
0.38
0.64
10
10
A
ILE
0.65
0.64
0.63
10
14
A
LYS
0.76
0.25
0.55
7
18
A
VAL
0.79
0.56
0.46
7
22
A
ALA
0.82
0.38
0.39
1
25
A
TRP
1.00
0.99
0.14
10
26
A
GLN
0.35
0.43
0.56
10
27
A
ILE
0.46
0.64
0.51
7
28
A
ASN
0.26
0.39
0.70
7
29
A
GLY
0.56
0.41
0.69
7
30
A
GLU
0.37
0.33
0.77
3
32
A
GLU
0.74
0.33
0.51
1
33
A
LEU
0.30
0.70
0.69
7
35
A
LEU
0.59
0.70
0.42
10
36
A
LEU
0.70
0.70
0.48
10
37
A
GLN
0.40
0.43
0.70
10
38
A
GLN
0.31
0.43
0.68
10
40
A
ALA
0.67
0.38
0.53
10
41
A
GLN
0.51
0.43
0.68
10
42
A
LYS
0.52
0.25
0.61
9
43
A
PRO
0.76
0.47
0.48
10
44
A
GLY
1.00
0.41
0.58
10
45
A
ALA
0.74
0.38
0.53
10
46
A
LEU
0.82
0.70
0.34
10
47
A
ARG
0.97
0.51
0.58
10
48
A
ILE
0.45
0.64
0.49
10
49
A
LEU
0.62
0.70
0.24
10
51
A
HIS
0.48
0.60
0.45
10
54
A
ARG
0.60
0.51
0.47
10
56
A
ALA
1.00
0.38
0.22
10
57
A
ALA
0.45
0.38
0.48
10
58
A
MET
0.67
0.66
0.55
10
59
A
THR
0.36
0.33
0.65
10
60
A
ALA
1.00
0.38
0.70
10
61
A
HIS
0.33
0.60
0.60
10
62
A
GLY
0.81
0.41
0.76
10
63
A
LYS
0.29
0.25
0.74
10
64
A
GLY
0.62
0.41
0.68
10
65
A
GLU
0.08
0.33
0.62
10
66
A
ARG
0.37
0.51
0.72
9
70
A
ASP
0.27
0.32
0.61
1
71
A
TYR
0.50
0.80
0.47
10
73
A
ARG
0.43
0.51
0.47
7
74
A
GLN
0.22
0.43
0.57
9
77
A
ARG
0.46
0.51
0.50
7
79
A
LEU
0.71
0.70
0.55
9
80
A
ASP
0.49
0.32
0.59
1
81
A
LEU
0.32
0.70
0.41
1
85
A
ILE
0.16
0.64
0.47
9