Pre-computed interfaces

How to use JET2 Viewer

References

Contact

JET2 Viewer

Pre-computed interfaces from JET2

PDB Structure: 1G84 chain A sc2

 

Download file

 

 Residue 
 Chain 
 Type 
 Evolutionary conservation
TJET 
 Physico-chemical properties
PC 
 Circular variance
CV 
 #detections 
1
A
SER
0.05
0.36
0.83
1
2
A
ARG
0.03
0.51
0.76
1
3
A
ASP
0.03
0.32
0.70
1
4
A
PHE
0.16
1.00
0.59
10
6
A
PRO
0.39
0.47
0.57
10
7
A
PRO
0.99
0.47
0.43
9
9
A
VAL
0.94
0.56
0.27
9
10
A
LYS
0.62
0.25
0.49
9
11
A
ILE
0.55
0.64
0.33
9
12
A
LEU
0.71
0.70
0.45
9
13
A
GLN
0.73
0.43
0.44
8
14
A
SER
0.82
0.36
0.45
8
15
A
SER
0.88
0.36
0.48
8
16
A
SER
0.51
0.36
0.64
8
17
A
ASP
0.63
0.32
0.64
8
18
A
GLY
0.68
0.41
0.64
8
19
A
GLY
0.73
0.41
0.69
8
20
A
GLY
0.31
0.41
0.75
8
21
A
HIS
0.47
0.60
0.79
8
22
A
PHE
0.60
1.00
0.70
8
23
A
PRO
0.63
0.47
0.62
5
29
A
LEU
0.85
0.70
0.31
9
31
A
LEU
0.68
0.70
0.36
9
36
A
THR
0.72
0.33
0.41
6
37
A
PRO
0.99
0.47
0.56
10
38
A
GLY
0.57
0.41
0.54
9
40
A
ILE
0.67
0.64
0.28
10
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.28
9
44
A
TRP
1.00
0.99
0.06
9
45
A
LEU
0.81
0.70
0.47
1
47
A
ASP
0.76
0.32
0.55
1
48
A
GLY
0.78
0.41
0.58
1
49
A
GLN
0.60
0.43
0.65
1
50
A
VAL
0.60
0.56
0.55
1
55
A
LEU
0.67
0.70
0.42
5
57
A
THR
0.70
0.33
0.40
4
59
A
SER
0.55
0.36
0.50
7
60
A
THR
0.67
0.33
0.55
10
61
A
THR
0.61
0.33
0.58
10
62
A
GLN
0.61
0.43
0.73
10
63
A
GLU
0.78
0.33
0.62
10
64
A
GLY
0.74
0.41
0.71
10
65
A
GLU
0.65
0.33
0.66
10
66
A
LEU
0.70
0.70
0.54
10
68
A
SER
0.79
0.36
0.44
9
70
A
GLN
0.76
0.43
0.41
9
72
A
GLU
0.69
0.33
0.30
1
84
A
ARG
0.35
0.51
0.45
1
91
A
THR
0.58
0.33
0.45
9
92
A
TYR
0.86
0.80
0.35
10
93
A
GLN
0.68
0.43
0.59
10
94
A
GLY
0.68
0.41
0.64
10
95
A
HIS
0.42
0.60
0.57
10
96
A
THR
0.49
0.33
0.55
9
97
A
PHE
0.45
1.00
0.46
9
1
A
SER
0.05
0.36
0.85
1
2
A
ARG
0.03
0.51
0.77
1
3
A
ASP
0.03
0.32
0.68
10
4
A
PHE
0.16
1.00
0.56
10
6
A
PRO
0.39
0.47
0.59
9
7
A
PRO
0.99
0.47
0.47
3
8
A
THR
0.50
0.33
0.46
1
9
A
VAL
0.94
0.56
0.32
4
10
A
LYS
0.62
0.25
0.52
7
11
A
ILE
0.55
0.64
0.32
8
12
A
LEU
0.71
0.70
0.45
7
13
A
GLN
0.73
0.43
0.48
5
14
A
SER
0.82
0.36
0.46
5
15
A
SER
0.88
0.36
0.48
4
16
A
SER
0.51
0.36
0.62
2
17
A
ASP
0.63
0.32
0.63
4
18
A
GLY
0.68
0.41
0.68
3
19
A
GLY
0.73
0.41
0.74
3
20
A
GLY
0.31
0.41
0.75
2
24
A
PRO
0.47
0.47
0.57
2
29
A
LEU
0.85
0.70
0.32
9
31
A
LEU
0.68
0.70
0.36
9
36
A
THR
0.72
0.33
0.40
3
37
A
PRO
0.99
0.47
0.54
10
38
A
GLY
0.57
0.41
0.53
10
40
A
ILE
0.67
0.64
0.29
10
42
A
ILE
0.81
0.64
0.31
10
44
A
TRP
1.00
0.99
0.09
7
45
A
LEU
0.81
0.70
0.48
2
47
A
ASP
0.76
0.32
0.59
2
48
A
GLY
0.78
0.41
0.62
2
49
A
GLN
0.60
0.43
0.68
2
50
A
VAL
0.60
0.56
0.60
2
51
A
MET
0.48
0.66
0.58
2
52
A
ASP
0.39
0.32
0.72
2
53
A
VAL
0.57
0.56
0.62
2
55
A
LEU
0.67
0.70
0.44
4
57
A
THR
0.70
0.33
0.41
3
59
A
SER
0.55
0.36
0.51
7
60
A
THR
0.67
0.33
0.54
10
61
A
THR
0.61
0.33
0.59
10
62
A
GLN
0.61
0.43
0.71
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.71
10
65
A
GLU
0.65
0.33
0.65
10
66
A
LEU
0.70
0.70
0.54
10
68
A
SER
0.79
0.36
0.44
9
70
A
GLN
0.76
0.43
0.42
10
78
A
LYS
0.38
0.25
0.63
2
79
A
HIS
0.51
0.60
0.49
2
80
A
TRP
0.89
0.99
0.36
2
81
A
LEU
0.42
0.70
0.63
2
82
A
SER
0.63
0.36
0.64
2
83
A
ASP
0.73
0.32
0.61
2
85
A
THR
0.76
0.33
0.46
2
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.65
10
95
A
HIS
0.42
0.60
0.60
10
96
A
THR
0.49
0.33
0.58
8
97
A
PHE
0.45
1.00
0.41
4
103
A
LYS
0.43
0.25
0.65
2
104
A
SER
0.32
0.36
0.61
2
105
A
ALA
0.20
0.38
0.66
3
4
A
PHE
0.16
1.00
0.59
10
6
A
PRO
0.39
0.47
0.59
9
7
A
PRO
0.99
0.47
0.45
9
9
A
VAL
0.94
0.56
0.30
9
10
A
LYS
0.62
0.25
0.52
9
11
A
ILE
0.55
0.64
0.31
9
12
A
LEU
0.71
0.70
0.43
9
13
A
GLN
0.73
0.43
0.45
7
14
A
SER
0.82
0.36
0.45
5
16
A
SER
0.51
0.36
0.59
3
17
A
ASP
0.63
0.32
0.67
4
18
A
GLY
0.68
0.41
0.77
4
19
A
GLY
0.73
0.41
0.75
4
20
A
GLY
0.31
0.41
0.67
4
21
A
HIS
0.47
0.60
0.72
4
22
A
PHE
0.60
1.00
0.74
4
24
A
PRO
0.47
0.47
0.60
3
29
A
LEU
0.85
0.70
0.31
9
31
A
LEU
0.68
0.70
0.36
9
36
A
THR
0.72
0.33
0.42
7
37
A
PRO
0.99
0.47
0.58
10
38
A
GLY
0.57
0.41
0.56
9
40
A
ILE
0.67
0.64
0.28
9
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.30
9
44
A
TRP
1.00
0.99
0.09
7
45
A
LEU
0.81
0.70
0.48
3
47
A
ASP
0.76
0.32
0.57
3
48
A
GLY
0.78
0.41
0.58
3
49
A
GLN
0.60
0.43
0.70
3
50
A
VAL
0.60
0.56
0.58
3
51
A
MET
0.48
0.66
0.75
3
52
A
ASP
0.39
0.32
0.61
3
53
A
VAL
0.57
0.56
0.67
1
55
A
LEU
0.67
0.70
0.45
6
57
A
THR
0.70
0.33
0.41
5
59
A
SER
0.55
0.36
0.50
7
60
A
THR
0.67
0.33
0.54
9
61
A
THR
0.61
0.33
0.60
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.66
10
64
A
GLY
0.74
0.41
0.76
10
65
A
GLU
0.65
0.33
0.69
10
66
A
LEU
0.70
0.70
0.56
10
68
A
SER
0.79
0.36
0.45
9
70
A
GLN
0.76
0.43
0.38
9
72
A
GLU
0.69
0.33
0.31
2
78
A
LYS
0.38
0.25
0.64
3
79
A
HIS
0.51
0.60
0.46
3
80
A
TRP
0.89
0.99
0.35
3
81
A
LEU
0.42
0.70
0.60
3
82
A
SER
0.63
0.36
0.61
3
83
A
ASP
0.73
0.32
0.60
3
91
A
THR
0.58
0.33
0.45
9
92
A
TYR
0.86
0.80
0.36
9
93
A
GLN
0.68
0.43
0.59
10
94
A
GLY
0.68
0.41
0.64
9
95
A
HIS
0.42
0.60
0.58
9
96
A
THR
0.49
0.33
0.55
9
97
A
PHE
0.45
1.00
0.38
9
103
A
LYS
0.43
0.25
0.61
3
104
A
SER
0.32
0.36
0.69
3
105
A
ALA
0.20
0.38
0.66
3
1
A
SER
0.05
0.36
0.81
1
2
A
ARG
0.03
0.51
0.77
1
3
A
ASP
0.03
0.32
0.64
10
4
A
PHE
0.16
1.00
0.64
10
5
A
THR
0.28
0.33
0.57
9
6
A
PRO
0.39
0.47
0.58
10
7
A
PRO
0.99
0.47
0.41
9
8
A
THR
0.50
0.33
0.51
9
9
A
VAL
0.94
0.56
0.31
9
10
A
LYS
0.62
0.25
0.51
9
11
A
ILE
0.55
0.64
0.32
9
12
A
LEU
0.71
0.70
0.48
9
13
A
GLN
0.73
0.43
0.46
9
14
A
SER
0.82
0.36
0.46
9
15
A
SER
0.88
0.36
0.49
2
16
A
SER
0.51
0.36
0.61
6
17
A
ASP
0.63
0.32
0.67
5
18
A
GLY
0.68
0.41
0.75
5
19
A
GLY
0.73
0.41
0.74
5
20
A
GLY
0.31
0.41
0.72
5
21
A
HIS
0.47
0.60
0.79
5
22
A
PHE
0.60
1.00
0.71
2
23
A
PRO
0.63
0.47
0.61
2
27
A
GLN
0.63
0.43
0.38
9
29
A
LEU
0.85
0.70
0.31
9
31
A
LEU
0.68
0.70
0.39
9
37
A
PRO
0.99
0.47
0.59
10
38
A
GLY
0.57
0.41
0.53
10
41
A
ASN
0.45
0.39
0.47
8
42
A
ILE
0.81
0.64
0.30
10
44
A
TRP
1.00
0.99
0.08
9
45
A
LEU
0.81
0.70
0.49
3
47
A
ASP
0.76
0.32
0.58
2
48
A
GLY
0.78
0.41
0.60
2
49
A
GLN
0.60
0.43
0.68
2
50
A
VAL
0.60
0.56
0.58
2
51
A
MET
0.48
0.66
0.63
2
55
A
LEU
0.67
0.70
0.43
7
57
A
THR
0.70
0.33
0.41
7
59
A
SER
0.55
0.36
0.51
3
60
A
THR
0.67
0.33
0.58
10
61
A
THR
0.61
0.33
0.60
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.62
10
64
A
GLY
0.74
0.41
0.72
10
65
A
GLU
0.65
0.33
0.69
10
66
A
LEU
0.70
0.70
0.54
10
68
A
SER
0.79
0.36
0.44
8
70
A
GLN
0.76
0.43
0.41
9
72
A
GLU
0.69
0.33
0.32
5
79
A
HIS
0.51
0.60
0.47
2
80
A
TRP
0.89
0.99
0.33
8
81
A
LEU
0.42
0.70
0.62
2
82
A
SER
0.63
0.36
0.62
2
83
A
ASP
0.73
0.32
0.61
2
85
A
THR
0.76
0.33
0.46
1
93
A
GLN
0.68
0.43
0.58
10
94
A
GLY
0.68
0.41
0.63
7
95
A
HIS
0.42
0.60
0.56
10
96
A
THR
0.49
0.33
0.56
5
97
A
PHE
0.45
1.00
0.43
10
104
A
SER
0.32
0.36
0.70
2
105
A
ALA
0.20
0.38
0.67
2
1
A
SER
0.05
0.36
0.86
1
2
A
ARG
0.03
0.51
0.76
1
3
A
ASP
0.03
0.32
0.71
1
4
A
PHE
0.16
1.00
0.58
10
6
A
PRO
0.39
0.47
0.56
10
7
A
PRO
0.99
0.47
0.42
2
9
A
VAL
0.94
0.56
0.26
7
10
A
LYS
0.62
0.25
0.47
9
11
A
ILE
0.55
0.64
0.28
9
12
A
LEU
0.71
0.70
0.41
10
13
A
GLN
0.73
0.43
0.43
8
14
A
SER
0.82
0.36
0.44
6
15
A
SER
0.88
0.36
0.44
6
16
A
SER
0.51
0.36
0.60
6
17
A
ASP
0.63
0.32
0.67
6
18
A
GLY
0.68
0.41
0.59
6
19
A
GLY
0.73
0.41
0.67
6
20
A
GLY
0.31
0.41
0.75
6
21
A
HIS
0.47
0.60
0.80
6
22
A
PHE
0.60
1.00
0.66
6
23
A
PRO
0.63
0.47
0.56
6
29
A
LEU
0.85
0.70
0.30
10
31
A
LEU
0.68
0.70
0.32
10
36
A
THR
0.72
0.33
0.42
4
37
A
PRO
0.99
0.47
0.58
10
38
A
GLY
0.57
0.41
0.57
10
40
A
ILE
0.67
0.64
0.29
10
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.30
10
43
A
THR
0.61
0.33
0.36
1
44
A
TRP
1.00
0.99
0.08
9
45
A
LEU
0.81
0.70
0.46
9
47
A
ASP
0.76
0.32
0.54
7
48
A
GLY
0.78
0.41
0.56
7
49
A
GLN
0.60
0.43
0.68
7
50
A
VAL
0.60
0.56
0.67
7
51
A
MET
0.48
0.66
0.73
7
52
A
ASP
0.39
0.32
0.72
3
53
A
VAL
0.57
0.56
0.52
7
55
A
LEU
0.67
0.70
0.43
9
57
A
THR
0.70
0.33
0.42
9
58
A
ALA
0.61
0.38
0.29
2
59
A
SER
0.55
0.36
0.51
9
60
A
THR
0.67
0.33
0.56
10
61
A
THR
0.61
0.33
0.59
10
62
A
GLN
0.61
0.43
0.73
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.75
10
65
A
GLU
0.65
0.33
0.70
10
66
A
LEU
0.70
0.70
0.57
10
68
A
SER
0.79
0.36
0.44
9
70
A
GLN
0.76
0.43
0.39
10
72
A
GLU
0.69
0.33
0.34
9
77
A
GLN
0.66
0.43
0.48
3
78
A
LYS
0.38
0.25
0.64
8
79
A
HIS
0.51
0.60
0.46
8
80
A
TRP
0.89
0.99
0.35
9
81
A
LEU
0.42
0.70
0.62
8
82
A
SER
0.63
0.36
0.61
8
83
A
ASP
0.73
0.32
0.60
8
85
A
THR
0.76
0.33
0.43
5
91
A
THR
0.58
0.33
0.45
9
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.62
10
95
A
HIS
0.42
0.60
0.53
10
96
A
THR
0.49
0.33
0.55
10
97
A
PHE
0.45
1.00
0.44
8
105
A
ALA
0.20
0.38
0.68
8
1
A
SER
0.05
0.36
0.87
1
2
A
ARG
0.03
0.51
0.75
1
3
A
ASP
0.03
0.32
0.71
1
4
A
PHE
0.16
1.00
0.59
10
6
A
PRO
0.39
0.47
0.58
10
7
A
PRO
0.99
0.47
0.46
10
9
A
VAL
0.94
0.56
0.30
9
10
A
LYS
0.62
0.25
0.51
9
11
A
ILE
0.55
0.64
0.32
9
12
A
LEU
0.71
0.70
0.42
9
13
A
GLN
0.73
0.43
0.42
9
14
A
SER
0.82
0.36
0.47
6
15
A
SER
0.88
0.36
0.48
7
16
A
SER
0.51
0.36
0.64
7
17
A
ASP
0.63
0.32
0.72
7
18
A
GLY
0.68
0.41
0.65
6
19
A
GLY
0.73
0.41
0.68
4
20
A
GLY
0.31
0.41
0.59
4
21
A
HIS
0.47
0.60
0.75
4
22
A
PHE
0.60
1.00
0.74
4
23
A
PRO
0.63
0.47
0.55
7
24
A
PRO
0.47
0.47
0.62
2
27
A
GLN
0.63
0.43
0.42
5
29
A
LEU
0.85
0.70
0.30
9
31
A
LEU
0.68
0.70
0.38
9
37
A
PRO
0.99
0.47
0.56
10
38
A
GLY
0.57
0.41
0.55
10
40
A
ILE
0.67
0.64
0.28
9
42
A
ILE
0.81
0.64
0.30
9
44
A
TRP
1.00
0.99
0.07
9
45
A
LEU
0.81
0.70
0.46
6
47
A
ASP
0.76
0.32
0.57
6
48
A
GLY
0.78
0.41
0.57
6
49
A
GLN
0.60
0.43
0.51
6
50
A
VAL
0.60
0.56
0.72
6
51
A
MET
0.48
0.66
0.76
6
52
A
ASP
0.39
0.32
0.60
6
53
A
VAL
0.57
0.56
0.66
1
55
A
LEU
0.67
0.70
0.46
8
57
A
THR
0.70
0.33
0.41
8
58
A
ALA
0.61
0.38
0.29
1
59
A
SER
0.55
0.36
0.51
9
60
A
THR
0.67
0.33
0.54
8
61
A
THR
0.61
0.33
0.58
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.72
10
65
A
GLU
0.65
0.33
0.67
10
66
A
LEU
0.70
0.70
0.53
10
68
A
SER
0.79
0.36
0.42
9
70
A
GLN
0.76
0.43
0.42
9
72
A
GLU
0.69
0.33
0.32
3
77
A
GLN
0.66
0.43
0.51
3
78
A
LYS
0.38
0.25
0.63
6
79
A
HIS
0.51
0.60
0.49
6
80
A
TRP
0.89
0.99
0.33
6
81
A
LEU
0.42
0.70
0.57
7
82
A
SER
0.63
0.36
0.61
6
83
A
ASP
0.73
0.32
0.60
6
85
A
THR
0.76
0.33
0.44
2
91
A
THR
0.58
0.33
0.45
9
93
A
GLN
0.68
0.43
0.61
10
94
A
GLY
0.68
0.41
0.65
10
95
A
HIS
0.42
0.60
0.58
10
96
A
THR
0.49
0.33
0.56
9
97
A
PHE
0.45
1.00
0.44
10
104
A
SER
0.32
0.36
0.69
6
105
A
ALA
0.20
0.38
0.65
6
1
A
SER
0.05
0.36
0.83
1
2
A
ARG
0.03
0.51
0.78
1
3
A
ASP
0.03
0.32
0.68
9
4
A
PHE
0.16
1.00
0.58
10
6
A
PRO
0.39
0.47
0.58
10
7
A
PRO
0.99
0.47
0.43
8
8
A
THR
0.50
0.33
0.45
1
9
A
VAL
0.94
0.56
0.29
9
10
A
LYS
0.62
0.25
0.50
9
11
A
ILE
0.55
0.64
0.29
9
12
A
LEU
0.71
0.70
0.38
9
13
A
GLN
0.73
0.43
0.44
9
14
A
SER
0.82
0.36
0.44
9
15
A
SER
0.88
0.36
0.47
9
16
A
SER
0.51
0.36
0.62
9
17
A
ASP
0.63
0.32
0.64
9
18
A
GLY
0.68
0.41
0.68
9
19
A
GLY
0.73
0.41
0.79
9
20
A
GLY
0.31
0.41
0.80
9
21
A
HIS
0.47
0.60
0.78
9
22
A
PHE
0.60
1.00
0.64
9
23
A
PRO
0.63
0.47
0.62
9
29
A
LEU
0.85
0.70
0.29
9
31
A
LEU
0.68
0.70
0.35
9
36
A
THR
0.72
0.33
0.42
8
37
A
PRO
0.99
0.47
0.56
10
38
A
GLY
0.57
0.41
0.56
9
40
A
ILE
0.67
0.64
0.28
9
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.32
10
44
A
TRP
1.00
0.99
0.09
9
45
A
LEU
0.81
0.70
0.46
7
48
A
GLY
0.78
0.41
0.57
1
50
A
VAL
0.60
0.56
0.58
3
51
A
MET
0.48
0.66
0.75
2
52
A
ASP
0.39
0.32
0.61
2
53
A
VAL
0.57
0.56
0.66
3
55
A
LEU
0.67
0.70
0.45
8
57
A
THR
0.70
0.33
0.42
8
58
A
ALA
0.61
0.38
0.31
3
59
A
SER
0.55
0.36
0.52
9
60
A
THR
0.67
0.33
0.56
10
61
A
THR
0.61
0.33
0.60
10
62
A
GLN
0.61
0.43
0.74
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.74
10
65
A
GLU
0.65
0.33
0.69
10
66
A
LEU
0.70
0.70
0.56
10
68
A
SER
0.79
0.36
0.45
9
70
A
GLN
0.76
0.43
0.42
9
72
A
GLU
0.69
0.33
0.32
8
78
A
LYS
0.38
0.25
0.66
1
80
A
TRP
0.89
0.99
0.37
6
81
A
LEU
0.42
0.70
0.65
1
82
A
SER
0.63
0.36
0.64
1
83
A
ASP
0.73
0.32
0.63
1
91
A
THR
0.58
0.33
0.46
4
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.62
9
95
A
HIS
0.42
0.60
0.55
9
96
A
THR
0.49
0.33
0.56
6
97
A
PHE
0.45
1.00
0.46
7
103
A
LYS
0.43
0.25
0.65
1
104
A
SER
0.32
0.36
0.62
1
105
A
ALA
0.20
0.38
0.64
1
1
A
SER
0.05
0.36
0.85
1
2
A
ARG
0.03
0.51
0.76
1
3
A
ASP
0.03
0.32
0.71
1
4
A
PHE
0.16
1.00
0.57
10
6
A
PRO
0.39
0.47
0.58
10
7
A
PRO
0.99
0.47
0.43
7
8
A
THR
0.50
0.33
0.44
2
9
A
VAL
0.94
0.56
0.30
8
10
A
LYS
0.62
0.25
0.51
8
11
A
ILE
0.55
0.64
0.31
8
12
A
LEU
0.71
0.70
0.44
8
13
A
GLN
0.73
0.43
0.45
8
14
A
SER
0.82
0.36
0.46
6
15
A
SER
0.88
0.36
0.45
3
16
A
SER
0.51
0.36
0.61
7
17
A
ASP
0.63
0.32
0.71
3
18
A
GLY
0.68
0.41
0.67
3
19
A
GLY
0.73
0.41
0.67
3
20
A
GLY
0.31
0.41
0.66
3
21
A
HIS
0.47
0.60
0.72
3
22
A
PHE
0.60
1.00
0.77
3
23
A
PRO
0.63
0.47
0.63
3
24
A
PRO
0.47
0.47
0.59
3
29
A
LEU
0.85
0.70
0.31
9
31
A
LEU
0.68
0.70
0.37
9
37
A
PRO
0.99
0.47
0.58
10
38
A
GLY
0.57
0.41
0.57
10
40
A
ILE
0.67
0.64
0.29
10
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.27
10
44
A
TRP
1.00
0.99
0.07
9
45
A
LEU
0.81
0.70
0.47
7
47
A
ASP
0.76
0.32
0.58
7
48
A
GLY
0.78
0.41
0.57
5
50
A
VAL
0.60
0.56
0.71
5
51
A
MET
0.48
0.66
0.71
6
52
A
ASP
0.39
0.32
0.63
6
53
A
VAL
0.57
0.56
0.64
4
55
A
LEU
0.67
0.70
0.44
9
57
A
THR
0.70
0.33
0.41
9
59
A
SER
0.55
0.36
0.51
10
60
A
THR
0.67
0.33
0.55
10
61
A
THR
0.61
0.33
0.60
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.65
10
64
A
GLY
0.74
0.41
0.76
10
65
A
GLU
0.65
0.33
0.71
10
66
A
LEU
0.70
0.70
0.56
10
68
A
SER
0.79
0.36
0.45
9
70
A
GLN
0.76
0.43
0.37
9
72
A
GLU
0.69
0.33
0.29
8
78
A
LYS
0.38
0.25
0.66
4
79
A
HIS
0.51
0.60
0.50
6
80
A
TRP
0.89
0.99
0.37
6
81
A
LEU
0.42
0.70
0.64
4
82
A
SER
0.63
0.36
0.64
4
83
A
ASP
0.73
0.32
0.61
5
85
A
THR
0.76
0.33
0.46
3
91
A
THR
0.58
0.33
0.44
1
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.63
10
95
A
HIS
0.42
0.60
0.56
10
96
A
THR
0.49
0.33
0.55
10
97
A
PHE
0.45
1.00
0.40
9
103
A
LYS
0.43
0.25
0.65
4
104
A
SER
0.32
0.36
0.62
4
105
A
ALA
0.20
0.38
0.62
4
1
A
SER
0.05
0.36
0.81
1
2
A
ARG
0.03
0.51
0.79
1
3
A
ASP
0.03
0.32
0.69
1
4
A
PHE
0.16
1.00
0.57
10
6
A
PRO
0.39
0.47
0.58
10
7
A
PRO
0.99
0.47
0.43
4
9
A
VAL
0.94
0.56
0.28
3
10
A
LYS
0.62
0.25
0.49
1
11
A
ILE
0.55
0.64
0.33
9
12
A
LEU
0.71
0.70
0.46
9
13
A
GLN
0.73
0.43
0.49
9
14
A
SER
0.82
0.36
0.48
9
15
A
SER
0.88
0.36
0.49
9
16
A
SER
0.51
0.36
0.62
9
17
A
ASP
0.63
0.32
0.70
9
18
A
GLY
0.68
0.41
0.68
9
19
A
GLY
0.73
0.41
0.72
9
20
A
GLY
0.31
0.41
0.75
9
21
A
HIS
0.47
0.60
0.81
9
22
A
PHE
0.60
1.00
0.68
9
23
A
PRO
0.63
0.47
0.60
4
27
A
GLN
0.63
0.43
0.40
2
29
A
LEU
0.85
0.70
0.33
9
31
A
LEU
0.68
0.70
0.38
9
36
A
THR
0.72
0.33
0.42
4
37
A
PRO
0.99
0.47
0.57
10
38
A
GLY
0.57
0.41
0.55
9
40
A
ILE
0.67
0.64
0.29
9
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.31
9
44
A
TRP
1.00
0.99
0.07
9
45
A
LEU
0.81
0.70
0.48
2
47
A
ASP
0.76
0.32
0.57
2
48
A
GLY
0.78
0.41
0.59
2
49
A
GLN
0.60
0.43
0.73
2
50
A
VAL
0.60
0.56
0.47
2
51
A
MET
0.48
0.66
0.68
1
55
A
LEU
0.67
0.70
0.44
7
57
A
THR
0.70
0.33
0.41
7
59
A
SER
0.55
0.36
0.51
6
60
A
THR
0.67
0.33
0.56
10
61
A
THR
0.61
0.33
0.56
8
62
A
GLN
0.61
0.43
0.73
10
63
A
GLU
0.78
0.33
0.65
10
64
A
GLY
0.74
0.41
0.74
10
65
A
GLU
0.65
0.33
0.69
10
66
A
LEU
0.70
0.70
0.56
10
68
A
SER
0.79
0.36
0.42
8
70
A
GLN
0.76
0.43
0.42
9
72
A
GLU
0.69
0.33
0.31
3
79
A
HIS
0.51
0.60
0.44
2
80
A
TRP
0.89
0.99
0.36
1
81
A
LEU
0.42
0.70
0.61
1
82
A
SER
0.63
0.36
0.60
2
83
A
ASP
0.73
0.32
0.59
2
84
A
ARG
0.35
0.51
0.47
2
85
A
THR
0.76
0.33
0.46
1
89
A
GLN
0.45
0.43
0.37
9
93
A
GLN
0.68
0.43
0.58
10
94
A
GLY
0.68
0.41
0.62
8
95
A
HIS
0.42
0.60
0.56
9
96
A
THR
0.49
0.33
0.55
8
97
A
PHE
0.45
1.00
0.45
2
103
A
LYS
0.43
0.25
0.63
1
104
A
SER
0.32
0.36
0.68
1
105
A
ALA
0.20
0.38
0.63
1
1
A
SER
0.05
0.36
0.77
8
2
A
ARG
0.03
0.51
0.77
5
3
A
ASP
0.03
0.32
0.75
1
4
A
PHE
0.16
1.00
0.66
10
6
A
PRO
0.39
0.47
0.58
9
7
A
PRO
0.99
0.47
0.47
6
9
A
VAL
0.94
0.56
0.29
6
10
A
LYS
0.62
0.25
0.49
4
11
A
ILE
0.55
0.64
0.32
8
12
A
LEU
0.71
0.70
0.49
7
13
A
GLN
0.73
0.43
0.48
7
14
A
SER
0.82
0.36
0.48
7
15
A
SER
0.88
0.36
0.50
7
16
A
SER
0.51
0.36
0.65
7
17
A
ASP
0.63
0.32
0.72
7
18
A
GLY
0.68
0.41
0.70
7
19
A
GLY
0.73
0.41
0.71
7
20
A
GLY
0.31
0.41
0.66
7
21
A
HIS
0.47
0.60
0.77
7
22
A
PHE
0.60
1.00
0.75
7
23
A
PRO
0.63
0.47
0.62
7
29
A
LEU
0.85
0.70
0.34
9
31
A
LEU
0.68
0.70
0.37
9
36
A
THR
0.72
0.33
0.40
2
37
A
PRO
0.99
0.47
0.55
7
38
A
GLY
0.57
0.41
0.53
7
40
A
ILE
0.67
0.64
0.28
9
41
A
ASN
0.45
0.39
0.47
6
42
A
ILE
0.81
0.64
0.26
7
44
A
TRP
1.00
0.99
0.08
8
45
A
LEU
0.81
0.70
0.46
1
55
A
LEU
0.67
0.70
0.43
6
57
A
THR
0.70
0.33
0.43
6
59
A
SER
0.55
0.36
0.53
7
60
A
THR
0.67
0.33
0.56
8
61
A
THR
0.61
0.33
0.57
8
62
A
GLN
0.61
0.43
0.67
8
63
A
GLU
0.78
0.33
0.61
8
64
A
GLY
0.74
0.41
0.72
8
65
A
GLU
0.65
0.33
0.67
8
66
A
LEU
0.70
0.70
0.56
8
68
A
SER
0.79
0.36
0.40
5
70
A
GLN
0.76
0.43
0.44
7
91
A
THR
0.58
0.33
0.45
6
93
A
GLN
0.68
0.43
0.59
8
94
A
GLY
0.68
0.41
0.65
7
95
A
HIS
0.42
0.60
0.58
10
96
A
THR
0.49
0.33
0.55
4
97
A
PHE
0.45
1.00
0.44
6
1
A
SER
0.05
0.36
0.84
1
2
A
ARG
0.03
0.51
0.74
1
3
A
ASP
0.03
0.32
0.70
1
4
A
PHE
0.16
1.00
0.60
10
6
A
PRO
0.39
0.47
0.60
10
7
A
PRO
0.99
0.47
0.45
9
8
A
THR
0.50
0.33
0.45
5
9
A
VAL
0.94
0.56
0.27
9
10
A
LYS
0.62
0.25
0.51
9
11
A
ILE
0.55
0.64
0.26
9
12
A
LEU
0.71
0.70
0.39
8
13
A
GLN
0.73
0.43
0.44
8
14
A
SER
0.82
0.36
0.44
5
15
A
SER
0.88
0.36
0.46
3
16
A
SER
0.51
0.36
0.60
5
17
A
ASP
0.63
0.32
0.64
5
18
A
GLY
0.68
0.41
0.74
5
19
A
GLY
0.73
0.41
0.82
5
20
A
GLY
0.31
0.41
0.77
5
21
A
HIS
0.47
0.60
0.69
5
22
A
PHE
0.60
1.00
0.75
5
23
A
PRO
0.63
0.47
0.58
5
24
A
PRO
0.47
0.47
0.60
4
29
A
LEU
0.85
0.70
0.28
9
31
A
LEU
0.68
0.70
0.36
9
34
A
GLY
0.60
0.41
0.40
1
36
A
THR
0.72
0.33
0.40
9
37
A
PRO
0.99
0.47
0.56
10
38
A
GLY
0.57
0.41
0.55
9
40
A
ILE
0.67
0.64
0.27
9
41
A
ASN
0.45
0.39
0.45
9
42
A
ILE
0.81
0.64
0.29
9
44
A
TRP
1.00
0.99
0.09
9
45
A
LEU
0.81
0.70
0.47
1
50
A
VAL
0.60
0.56
0.58
1
55
A
LEU
0.67
0.70
0.44
9
57
A
THR
0.70
0.33
0.42
9
58
A
ALA
0.61
0.38
0.29
2
59
A
SER
0.55
0.36
0.51
8
60
A
THR
0.67
0.33
0.55
10
61
A
THR
0.61
0.33
0.59
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.65
10
64
A
GLY
0.74
0.41
0.74
10
65
A
GLU
0.65
0.33
0.70
10
66
A
LEU
0.70
0.70
0.56
10
68
A
SER
0.79
0.36
0.45
9
70
A
GLN
0.76
0.43
0.43
9
72
A
GLU
0.69
0.33
0.33
6
91
A
THR
0.58
0.33
0.43
3
92
A
TYR
0.86
0.80
0.34
9
93
A
GLN
0.68
0.43
0.58
9
94
A
GLY
0.68
0.41
0.63
9
95
A
HIS
0.42
0.60
0.56
9
96
A
THR
0.49
0.33
0.53
9
97
A
PHE
0.45
1.00
0.34
9
3
A
ASP
0.03
0.32
0.66
9
4
A
PHE
0.16
1.00
0.57
9
6
A
PRO
0.39
0.47
0.60
9
7
A
PRO
0.99
0.47
0.44
3
9
A
VAL
0.94
0.56
0.26
4
10
A
LYS
0.62
0.25
0.50
9
11
A
ILE
0.55
0.64
0.30
9
12
A
LEU
0.71
0.70
0.48
10
13
A
GLN
0.73
0.43
0.44
9
14
A
SER
0.82
0.36
0.49
10
15
A
SER
0.88
0.36
0.50
9
16
A
SER
0.51
0.36
0.62
10
17
A
ASP
0.63
0.32
0.69
10
18
A
GLY
0.68
0.41
0.68
10
19
A
GLY
0.73
0.41
0.78
10
20
A
GLY
0.31
0.41
0.80
10
21
A
HIS
0.47
0.60
0.80
10
22
A
PHE
0.60
1.00
0.65
10
23
A
PRO
0.63
0.47
0.55
9
24
A
PRO
0.47
0.47
0.58
9
27
A
GLN
0.63
0.43
0.43
9
29
A
LEU
0.85
0.70
0.35
10
31
A
LEU
0.68
0.70
0.38
9
36
A
THR
0.72
0.33
0.39
1
37
A
PRO
0.99
0.47
0.54
9
38
A
GLY
0.57
0.41
0.53
9
40
A
ILE
0.67
0.64
0.28
9
42
A
ILE
0.81
0.64
0.30
9
44
A
TRP
1.00
0.99
0.07
9
45
A
LEU
0.81
0.70
0.48
3
47
A
ASP
0.76
0.32
0.55
2
53
A
VAL
0.57
0.56
0.61
1
55
A
LEU
0.67
0.70
0.44
5
57
A
THR
0.70
0.33
0.43
4
59
A
SER
0.55
0.36
0.52
5
60
A
THR
0.67
0.33
0.57
9
61
A
THR
0.61
0.33
0.56
7
62
A
GLN
0.61
0.43
0.70
9
63
A
GLU
0.78
0.33
0.66
9
64
A
GLY
0.74
0.41
0.74
9
65
A
GLU
0.65
0.33
0.68
9
66
A
LEU
0.70
0.70
0.56
9
68
A
SER
0.79
0.36
0.42
8
70
A
GLN
0.76
0.43
0.46
9
72
A
GLU
0.69
0.33
0.36
3
80
A
TRP
0.89
0.99
0.31
9
81
A
LEU
0.42
0.70
0.56
1
93
A
GLN
0.68
0.43
0.57
9
94
A
GLY
0.68
0.41
0.62
5
95
A
HIS
0.42
0.60
0.55
5
96
A
THR
0.49
0.33
0.55
3
97
A
PHE
0.45
1.00
0.46
2
1
A
SER
0.05
0.36
0.84
1
2
A
ARG
0.03
0.51
0.77
1
3
A
ASP
0.03
0.32
0.67
9
4
A
PHE
0.16
1.00
0.60
10
6
A
PRO
0.39
0.47
0.60
10
7
A
PRO
0.99
0.47
0.44
6
9
A
VAL
0.94
0.56
0.27
6
10
A
LYS
0.62
0.25
0.50
9
11
A
ILE
0.55
0.64
0.30
9
12
A
LEU
0.71
0.70
0.48
9
13
A
GLN
0.73
0.43
0.47
9
14
A
SER
0.82
0.36
0.48
9
15
A
SER
0.88
0.36
0.50
9
16
A
SER
0.51
0.36
0.66
9
17
A
ASP
0.63
0.32
0.66
9
18
A
GLY
0.68
0.41
0.68
9
19
A
GLY
0.73
0.41
0.70
9
20
A
GLY
0.31
0.41
0.74
9
21
A
HIS
0.47
0.60
0.81
9
22
A
PHE
0.60
1.00
0.72
9
23
A
PRO
0.63
0.47
0.61
3
29
A
LEU
0.85
0.70
0.33
9
31
A
LEU
0.68
0.70
0.39
9
36
A
THR
0.72
0.33
0.43
5
37
A
PRO
0.99
0.47
0.58
10
38
A
GLY
0.57
0.41
0.56
9
40
A
ILE
0.67
0.64
0.27
9
41
A
ASN
0.45
0.39
0.47
9
42
A
ILE
0.81
0.64
0.31
9
44
A
TRP
1.00
0.99
0.10
9
45
A
LEU
0.81
0.70
0.47
9
47
A
ASP
0.76
0.32
0.56
9
48
A
GLY
0.78
0.41
0.55
9
49
A
GLN
0.60
0.43
0.67
9
50
A
VAL
0.60
0.56
0.59
9
51
A
MET
0.48
0.66
0.73
9
52
A
ASP
0.39
0.32
0.59
6
53
A
VAL
0.57
0.56
0.61
2
55
A
LEU
0.67
0.70
0.45
9
57
A
THR
0.70
0.33
0.44
9
59
A
SER
0.55
0.36
0.53
9
60
A
THR
0.67
0.33
0.57
10
61
A
THR
0.61
0.33
0.60
10
62
A
GLN
0.61
0.43
0.72
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.75
10
65
A
GLU
0.65
0.33
0.71
10
66
A
LEU
0.70
0.70
0.58
10
68
A
SER
0.79
0.36
0.45
9
70
A
GLN
0.76
0.43
0.44
9
72
A
GLU
0.69
0.33
0.33
6
79
A
HIS
0.51
0.60
0.44
9
80
A
TRP
0.89
0.99
0.37
9
81
A
LEU
0.42
0.70
0.60
3
82
A
SER
0.63
0.36
0.61
3
83
A
ASP
0.73
0.32
0.60
8
85
A
THR
0.76
0.33
0.45
3
89
A
GLN
0.45
0.43
0.36
9
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.62
10
95
A
HIS
0.42
0.60
0.56
10
96
A
THR
0.49
0.33
0.55
8
97
A
PHE
0.45
1.00
0.45
4
104
A
SER
0.32
0.36
0.72
3
105
A
ALA
0.20
0.38
0.77
3
4
A
PHE
0.16
1.00
0.62
10
6
A
PRO
0.39
0.47
0.48
9
7
A
PRO
0.99
0.47
0.45
10
9
A
VAL
0.94
0.56
0.24
7
10
A
LYS
0.62
0.25
0.50
8
11
A
ILE
0.55
0.64
0.32
9
12
A
LEU
0.71
0.70
0.46
9
13
A
GLN
0.73
0.43
0.43
9
14
A
SER
0.82
0.36
0.48
9
15
A
SER
0.88
0.36
0.51
3
16
A
SER
0.51
0.36
0.63
3
17
A
ASP
0.63
0.32
0.69
3
18
A
GLY
0.68
0.41
0.67
3
19
A
GLY
0.73
0.41
0.75
3
20
A
GLY
0.31
0.41
0.78
3
21
A
HIS
0.47
0.60
0.80
3
22
A
PHE
0.60
1.00
0.69
3
23
A
PRO
0.63
0.47
0.60
2
29
A
LEU
0.85
0.70
0.36
9
31
A
LEU
0.68
0.70
0.40
9
36
A
THR
0.72
0.33
0.41
4
37
A
PRO
0.99
0.47
0.56
10
38
A
GLY
0.57
0.41
0.55
10
40
A
ILE
0.67
0.64
0.30
10
42
A
ILE
0.81
0.64
0.32
9
44
A
TRP
1.00
0.99
0.09
9
45
A
LEU
0.81
0.70
0.48
1
47
A
ASP
0.76
0.32
0.58
1
48
A
GLY
0.78
0.41
0.58
1
49
A
GLN
0.60
0.43
0.66
1
50
A
VAL
0.60
0.56
0.73
1
51
A
MET
0.48
0.66
0.66
1
55
A
LEU
0.67
0.70
0.43
6
57
A
THR
0.70
0.33
0.43
6
59
A
SER
0.55
0.36
0.52
9
60
A
THR
0.67
0.33
0.58
10
61
A
THR
0.61
0.33
0.57
9
62
A
GLN
0.61
0.43
0.71
10
63
A
GLU
0.78
0.33
0.64
10
64
A
GLY
0.74
0.41
0.74
10
65
A
GLU
0.65
0.33
0.68
10
66
A
LEU
0.70
0.70
0.54
10
68
A
SER
0.79
0.36
0.44
9
70
A
GLN
0.76
0.43
0.45
10
72
A
GLU
0.69
0.33
0.37
1
79
A
HIS
0.51
0.60
0.46
1
80
A
TRP
0.89
0.99
0.35
4
81
A
LEU
0.42
0.70
0.61
1
82
A
SER
0.63
0.36
0.63
1
83
A
ASP
0.73
0.32
0.61
1
93
A
GLN
0.68
0.43
0.60
10
94
A
GLY
0.68
0.41
0.60
10
95
A
HIS
0.42
0.60
0.63
10
96
A
THR
0.49
0.33
0.57
10
97
A
PHE
0.45
1.00
0.46
10
103
A
LYS
0.43
0.25
0.65
1
104
A
SER
0.32
0.36
0.59
1
105
A
ALA
0.20
0.38
0.60
1
4
A
PHE
0.16
1.00
0.58
9
6
A
PRO
0.39
0.47
0.58
9
7
A
PRO
0.99
0.47
0.44
9
9
A
VAL
0.94
0.56
0.29
8
10
A
LYS
0.62
0.25
0.50
5
11
A
ILE
0.55
0.64
0.29
6
12
A
LEU
0.71
0.70
0.45
2
13
A
GLN
0.73
0.43
0.44
1
14
A
SER
0.82
0.36
0.44
1
17
A
ASP
0.63
0.32
0.63
2
18
A
GLY
0.68
0.41
0.72
2
19
A
GLY
0.73
0.41
0.81
2
20
A
GLY
0.31
0.41
0.80
2
21
A
HIS
0.47
0.60
0.76
2
22
A
PHE
0.60
1.00
0.68
2
24
A
PRO
0.47
0.47
0.59
2
29
A
LEU
0.85
0.70
0.32
9
31
A
LEU
0.68
0.70
0.37
9
34
A
GLY
0.60
0.41
0.39
2
37
A
PRO
0.99
0.47
0.56
9
38
A
GLY
0.57
0.41
0.55
9
40
A
ILE
0.67
0.64
0.26
9
41
A
ASN
0.45
0.39
0.46
9
42
A
ILE
0.81
0.64
0.30
9
44
A
TRP
1.00
0.99
0.09
7
45
A
LEU
0.81
0.70
0.47
2
47
A
ASP
0.76
0.32
0.56
1
48
A
GLY
0.78
0.41
0.57
1
49
A
GLN
0.60
0.43
0.69
1
50
A
VAL
0.60
0.56
0.55
1
51
A
MET
0.48
0.66
0.73
1
52
A
ASP
0.39
0.32
0.64
1
55
A
LEU
0.67
0.70
0.44
7
57
A
THR
0.70
0.33
0.41
7
58
A
ALA
0.61
0.38
0.28
4
59
A
SER
0.55
0.36
0.50
9
60
A
THR
0.67
0.33
0.54
9
61
A
THR
0.61
0.33
0.56
9
62
A
GLN
0.61
0.43
0.73
9
63
A
GLU
0.78
0.33
0.65
9
64
A
GLY
0.74
0.41
0.74
9
65
A
GLU
0.65
0.33
0.69
9
66
A
LEU
0.70
0.70
0.57
9
68
A
SER
0.79
0.36
0.42
9
70
A
GLN
0.76
0.43
0.41
9
72
A
GLU
0.69
0.33
0.32
1
78
A
LYS
0.38
0.25
0.63
2
79
A
HIS
0.51
0.60
0.48
1
80
A
TRP
0.89
0.99
0.35
3
81
A
LEU
0.42
0.70
0.62
2
82
A
SER
0.63
0.36
0.62
1
83
A
ASP
0.73
0.32
0.60
1
91
A
THR
0.58
0.33
0.43
1
92
A
TYR
0.86
0.80
0.32
9
93
A
GLN
0.68
0.43
0.56
9
94
A
GLY
0.68
0.41
0.58
9
95
A
HIS
0.42
0.60
0.61
9
96
A
THR
0.49
0.33
0.54
8
97
A
PHE
0.45
1.00
0.44
8
102
A
LYS
0.36
0.25
0.59
1
104
A
SER
0.32
0.36
0.70
2
105
A
ALA
0.20
0.38
0.67
2